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From Wikipedia, the free encyclopedia. The urea cycle (also known as the ornithine cycle) is a cycle of biochemical reactions occurring in many animals that produces urea ((NH2)2CO) from ammonia (NH3). This cycle was the first metabolic cycle discovered (Hans Krebs and Kurt Henseleit, 1932), five years before the discovery of the TCA cycle. In mammals, the urea cycle takes place primarily in the liver, and to a lesser extent in the kidney.
Some of the digested protein is stored in your muscles and the rest is turned into waste that your body doesnât need. The urea cycleâs job is to turn ammonia into a nontoxic component called urea, which is then eliminated. Those amino acids are used to build muscle, skin, blood cells, and more. This is what helps you grow and remain healthy. However, the urea cycle turns the rest of itâwhat your body doesnât needâinto ammoniaA waste product of protein digestion that is removed by the urea cycle process. and other waste products.