An IRB/IEC should have: 1  At least five members. 2  Members with varying backgrounds. 3  At least one member must represent a non-scientific area (a lay member) 4  At least one member must not be affiliated with the institution or the trial site (an independent member)
Vesicles and Vacuoles Vesicles and vacuoles are membrane-bound sacs that function in storage and transport. Vacuoles are somewhat larger than vesicles, and the membrane of a vacuole does not fuse with the membranes of other cellular components. Vesicles can fuse with other membranes within the cell system (Figure 1).
Vesicles play many roles within a cell. Since vesicles are composed of a lipid bilayer, they can have a completely self-contained environment that is different from the inside of the cell. There are essentially four types of vesicles used by cells. They are vacuoles, lysosomes, transport vesicles, and secretory vesicles.