A: The function of the cartilaginous rings of the trachea is to stabilize the trachea and keep it rigid while allowing the trachea to expand and lengthen when the person breathes. If the trachea was not supported in this way, it would simply collapse because of the pressure of the chest.
HCM remains the most common cardiovascular genetic disorder, occurring in at least 1 in 500 people in the general population. 7 HCM is a primary inherited disorder of the myocardium characterized by hypertrophy, usually of the left ventricle, in the absence of other loading conditions such as hypertension.
Congenital. 1  The most common inherited sideroblastic anaemia is X-linked sideroblastic anaemia (XLSA) caused by mutations of the erythroid-specific delta-aminolevulinic acid synthase 2 gene (ALAS2). 2  Congenital causes of sideroblastic anaemia also include Wolfram's syndrome. There are two types, each caused by a genetic error on a different chromasome. Wolfram's syndrome 1 is characterised by DIDMOAD (= Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy and Deafness).