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Vasopressin is a peptide hormone that increases water permeability of the kidney's collecting duct and distal convoluted tubule by inducing translocation of aquaporin-CD water channels in the plasma membrane of collecting duct cells.asopressin released within the brain has many actions: 1  Vasopressin is released into the brain in a circadian rhythm by neurons of the suprachiasmatic nucleus. 2  Vasopressin released from centrally projecting hypothalamic neurons is involved in aggression, blood pressure regulation, and temperature regulation.
Aquaporin-2 is the protein which is the vasopressin responsive water channel in the collecting duct. It is inserted into the apical membrane in reponse to cyclic AMP. The protein forms a tetrameric complex that spans the membrane and forms a channel which allows rapid water movement in response to an osmolar gradient.DH is a nonapeptide produced in the supraoptic and paraventricular nuclei and other areas of the hypothalamus. Its major role is in the regulation of water balance by its effect on the kidneys. ADH is also known as vasopressin because of the vasopressor response to pharmacological doses.