There are other ways your doctor can look for the cause of your enlarged liver. He may use an ERCP, a scope that checks for problems in the ducts (tubes) that carry bile. An MRCP, a special type of MRI, also helps spot that kind of trouble.
Cholestasis of pregnancy, also known as obstetric cholestasis or intrahepatic cholestasis of pregnancy, usually occurs during the last trimester of pregnancy, and triggers severe itching, especially on the hands and feet. On rare occasions symptoms may appear before the third trimester.
The sex of the patient does not seem to be associated with pruritus in systemic diseases. Certain causes of cholestasis are more common in women than in men. These include primary biliary cirrhosis (90% of patients are women) and cholestasis of pregnancy.