Drug distribution refers to the movement of a drug to and from the blood and various tissues of the body (for example, fat, muscle, and brain tissue) and the relative proportions of drug in the tissues. After a drug is absorbed into the bloodstream (see Drug Absorption), it rapidly circulates through the body.
The estimated minimum potassium requirements for women and men are 2000 mg per day. As children get older, they need more potassium and this increase can go up to 3800 â 4800 mg per day. A deficiency may cause muscular cramps, twitching, irregular heartbeat, kidney and lung failure and insomnia too.Daily potassium requirements: Potassium helps to maintain a healthy fluid balance in our body.s children get older, they need more potassium and this increase can go up to 3800 â 4800 mg per day. A deficiency may cause muscular cramps, twitching, irregular heartbeat, kidney and lung failure and insomnia too. Daily potassium requirements: Potassium helps to maintain a healthy fluid balance in our body.
The U.S. Centers for Disease Control and Prevention recommend that everyone limit sodium intake to below 2,300 mg per day and that everyone should also get at least 4,700 mg of potassium a day to help balance their levels of sodium and potassium in the body.he National Heart Lung and Blood Association reports that 500 mg is a safe daily minimum intake of sodium. This amount will be enough to maintain the bodily functions that require sodium. In an average temperate climate, a normal adult may be able to thrive with as little as 115 mg of sodium each day.