However, it is a known DNA mutagen, and this in turn could lead to carcinogenic effects. Acrolein has also been been linked with heart disease as a contributor, and is one of the most abundant chemicals in cigarette smoke.
1 Steroid hormones pass through the cell membrane of the target cell. 2  The steroid hormone binds with a specific receptor in the cytoplasm. 3  The receptor bound steroid hormone travels into the nucleus and binds to another specific receptor on the chromatin.teroid hormones cause changes within a cell by first passing through the cell membrane of the target cell. Steroid hormones, unlike non-steroid hormones, can do this because they are fat-soluble.
Another term used to describe this entire process is signal transduction. Receptors for steroid and thyroid hormones are located inside target cells, in the cytoplasm or nucleus, and function as ligand-dependent transcription factors.That is to say, the hormone-receptor complex binds to promoter regions of responsive genes and stimulate or sometimes inhibit transcription from those genes.eceptors for steroid and thyroid hormones are located inside target cells, in the cytoplasm or nucleus, and function as ligand-dependent transcription factors.