However, some people who have early-onset Alzheimer's don't have mutations in these three genes. That suggests that this early-onset form of Alzheimer's disease is linked to other genetic mutations that haven't been identified yet.
Early history Cigars, cigarettes Cancer by the carton Legal history Surgeon General's warning. (CNN) -- Tobacco was first used by the peoples of the pre-Columbian Americas. Native Americans apparently cultivated the plant and smoked it in pipes for medicinal and ceremonial purposes.
Report Abuse. Sir Walter Raleigh brought tobacco back to England after he discovered the North American Natives growing and smoking it. From all accounts it appears to have its started in Central and South America and gradually its cultivation and use was spread by the natives into the United States.eport Abuse. Sir Walter Raleigh brought tobacco back to England after he discovered the North American Natives growing and smoking it. From all accounts it appears to have its started in Central and South America and gradually its cultivation and use was spread by the natives into the United States.