However, some people who have early-onset Alzheimer's don't have mutations in these three genes. That suggests that this early-onset form of Alzheimer's disease is linked to other genetic mutations that haven't been identified yet.
Early history Cigars, cigarettes Cancer by the carton Legal history Surgeon General's warning. (CNN) -- Tobacco was first used by the peoples of the pre-Columbian Americas. Native Americans apparently cultivated the plant and smoked it in pipes for medicinal and ceremonial purposes.
Archaeologists have discovered tomb paintings of bundles of prickly lettuce and these have been dated to be 4,500 years old1. The first written records of lettuce cultivation and consumption was by the first ancient Greek historian, Herodotus. He recorded that lettuce appeared on the tables of the royal family of Persia in 550 BC.