A: The function of the cartilaginous rings of the trachea is to stabilize the trachea and keep it rigid while allowing the trachea to expand and lengthen when the person breathes. If the trachea was not supported in this way, it would simply collapse because of the pressure of the chest.
HCM remains the most common cardiovascular genetic disorder, occurring in at least 1 in 500 people in the general population. 7 HCM is a primary inherited disorder of the myocardium characterized by hypertrophy, usually of the left ventricle, in the absence of other loading conditions such as hypertension.
Genetic risk factors. About 5% to 10% of breast cancer cases are thought to be hereditary, meaning that they result directly from gene defects (called mutations) inherited from a parent. BRCA1 and BRCA2: The most common cause of hereditary breast cancer is an inherited mutation in the BRCA1 and BRCA2 genes. People with this syndrome have an increased risk of breast cancer, as well as several other cancers such as leukemia, brain tumors, and sarcomas (cancers of bones or connective tissue). 2  This is a rare cause of breast cancer. 3  CHEK2: The Li-Fraumeni syndrome can also be caused by inherited mutations in the CHEK2 gene.