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Short-acting insulin covers your insulin needs during meals. It is taken about 30 minutes to an hour before a meal to help control blood sugar levels. This type of insulin takes effect in about 30 minutes to one hour, and peaks after two to four hours. Its effects tend to last about five to eight hours.
Best Answer: Regular human insulin starts in 30 minutes and lasts about four hours with a peak between 1 and two hours. There are faster rapid insulins that work in 10 minutes. Common brands of regular human insulin are Novolog, type R, Humalog, and Novolin. Intermediate insulin like NPH takes two hours to start working, rises steadily to a peak in 9 hours and back down at the same rate for a total of 18 hours.