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The infusion time should not exceed 4 hours. Platelets, plasma and cryoprecipitate generally are transfused at a rate of 10 ml per minute. In order for a patient to receive maximum benefit platelets need to be transfused rapidly to get control of bleeding.
1 A dose of 1 random donor platelet concentrate per 10 kg body weight can be expected to increase the platelet count by 5000/uL in a non-refractory patient. 2  One random donor platelet concentrate is expected to increase the platelet count by 5000 to 10,000/uL in a 70 kg patient who is not refractory.