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An E-box (enhancer box) is a DNA response element found in some eukaryotes that acts as a protein-binding site and has been found to regulate gene expression in neurons, muscles, and other tissues.
This article is about boxes for depositing letters. For video framing, see letterbox. For the type of interprocess communication, see MailSlot. A letter box, letterbox, letter plate, letter hole, mail slot or mailbox is a receptacle for receiving incoming mail at a private residence or business. For the opposite purpose of collecting outgoing mail, a post box is generally used instead.