The rough endoplasmic reticulum synthesizes proteins while the function of the smooth endoplasmic reticula is to synthesize steroids and lipids; regulate calcium concentration, drug metabolism, as well as attachment of receptors on cell membrane proteins; and metabolize steroids (but not lipids) and carbohydrates.
Developing New Polymer-Based Medicines for Undertreated Conditions. Relypsa is a biopharmaceutical company leading the discovery, development and commercialization of polymer-based medicines to treat conditions that are often overlooked and undertreated, but that can have a serious impact on patient lives or even be life-threatening. We are focused on developing medicines that will change treatment paradigms.
Line Operations Safety Audit (LOSA) is seen as an important way to help develop countermeasures to operational errors.It involves a structured programme of observation of front line activities built around the Threat and Error Management (TEM) concept.ole of ICAO. ICAO has promoted the potential of LOSA and acted as an enabling partner in the LOSA programme. ICAO has developed a manual (Doc 9803) that provides an introduction to the concept, methodology and tools of LOSA and to the potential remedial actions which can be undertaken using the data collected.