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http://www.consumergenetics.com/caffeine_test.php. The lethal dose of caffeine is 2 grams of caffeine per day, that is, 80-100 cups of coffee a day.For slow metabolizers of caffeine, the lethal dose of caffeine can be lower.t's dependent on weight & individual sensitivity & estimated to be about 150-200 milligrams/kilogram of body mass. ChaCha on! [ Source: http://www.chacha.com/question/what-is-a-lethal-dose-of-caffeine ]. More Answers to  What is a lethal dose of caffeine .
Details. Created on Friday, 04 October 2013 21:17. Nicotine lethal dose in humans: a common argument by regulatory authorities, based on poor science. By Dr Farsalinos. I am sure everyone has heard the âmagic numberâ: 60mg is the nicotine lethal dose in adults.Ï his is a very low level, which would categorize nicotine as one of the most toxic substances available. always wondered how the lethal dose level was defined, because everyone mentioned that the lethal dose was just theoretical and was never really tested. In animals the lethal dose may be from 3mg/kg in mice to 50mg/kg in rats, while a 60mg dose means a 0.8mg/kg in humans.