Acute interstitial nephritis is an important cause of acute renal failure resulting from immune-mediated tubulointerstitial injury, initiated by medications, infection, and other causes. Acute interstitial nephritis may be implicated in up to 15 percent of patients hospitalized for acute renal failure.
The first player places one of their dominoes (right-side up) on the table. The second player tries to put a domino on the table that matches one side of what's already there. If a player cannot go, the player picks a domino from the pile and skips that turn. The chain of the played dominoes develops randomly, and can look a lot like a snake.
Just about any game you can play with a normal set of dominoes, you can play with this set. Since there are 49 dominoes in this set instead of 28, you can have larger groups of kids involved in the fraction activity. On the other hand, smaller groups will work just as well as they do for ordinary dominoes.