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IMPORTANT SAFETY INFORMATION. Indication: SoolantraÂ® (ivermectin) Cream, 1% is indicated for the treatment of inflammatory lesions of rosacea. Adverse Events: In clinical trials with SoolantraÂ® Cream, the most common adverse reactions (incidence â¤1%) included skin burning sensation and skin irritation.
1 Efficacy and safety of ivermectin 1% cream in treatment of papulopustular rosacea: results of two randomized, double-blind, vehicle-controlled pivotal studies. 2  J Drugs Dermatol. 2014;13:316-323. 3  Soolantra (ivermectin) cream, 1%, for topical use [prescribing information].