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The development of each chain is controlled at a separate genetic locus. Changes in the amino acid sequence of these chains results in abnormal hemoglobins. For example, hemoglobin S is found in sickle-cell disease, a severe type of anemia in which the red cells become sickle-shaped when oxygen is in short supply.
Definition. A high hemoglobin count indicates an above-average concentration of the oxygen-carrying protein hemoglobin in your blood. Hemoglobin (Hg or Hgb) is the main component of red blood cells. Hemoglobin count-also referred to as hemoglobin level-indicates your blood's oxygen-carrying capacity.A high hemoglobin count is somewhat different from a high red blood cell count, because each cell may not have the same amount of hemoglobin proteins.emoglobin (Hg or Hgb) is the main component of red blood cells. Hemoglobin count-also referred to as hemoglobin level-indicates your blood's oxygen-carrying capacity.