Drug distribution refers to the movement of a drug to and from the blood and various tissues of the body (for example, fat, muscle, and brain tissue) and the relative proportions of drug in the tissues. After a drug is absorbed into the bloodstream (see Drug Absorption), it rapidly circulates through the body.
The estimated minimum potassium requirements for women and men are 2000 mg per day. As children get older, they need more potassium and this increase can go up to 3800 â 4800 mg per day. A deficiency may cause muscular cramps, twitching, irregular heartbeat, kidney and lung failure and insomnia too.Daily potassium requirements: Potassium helps to maintain a healthy fluid balance in our body.s children get older, they need more potassium and this increase can go up to 3800 â 4800 mg per day. A deficiency may cause muscular cramps, twitching, irregular heartbeat, kidney and lung failure and insomnia too. Daily potassium requirements: Potassium helps to maintain a healthy fluid balance in our body.
To prevent potassium loss or replace potassium lost by the body: Adults and teenagersâ5 to 10 mEq taken two to four times a day. However, most people will not take more than 100 mEq a day. To prevent potassium loss: Adults and teenagersâ16 to 24 mEq a day, divided into two or three smaller doses during the day. Your doctor may change the dose if needed.  ChildrenâDose is based on body weight and must be determined by your doctor. The usual dose is 1 to 3 mEq of potassium per kilogram (kg) (0.45 to 1.36 mEq per pound) of body weight taken in smaller doses during the day. The solution should be well mixed in water or juice. For oral dosage form (powder for solution): To prevent potassium loss or replace potassium lost by the body: Adults and teenagersâ20 milliequivalents (mEq) mixed into one-half glass of cold water or juice, taken two to four times a day. Your doctor may change the dose if needed.