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Do not take more than eight Midol PMS capsules in a 24 hour period. Each Midol PMS tablet contains 500 milligrams (mg) of acetaminophen. The recommended daily adult dose for acetaminophen is four grams (4000 mg), or 1000 mg in a single dose.
The usual recommended starting dose of midodrine for adults is 2.5 mg 3 times daily, taken with or without food. Midodrine may also be taken as frequently as 6 times a day, as long as the maximum daily dose of 30 mg is not exceeded. The last midodrine dose of the day should be taken at least 4 hours before bedtime.