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What is metronomic chemotherapy? Metronomic chemotherapy (or low dose chemotherapy) is a treatment option for dogs and cats with a. variety of cancers. It may be used instead of or in addition to conventional chemotherapy. Metronomic. chemotherapy involves the use of low dose daily chemotherapy including the drugs cyclophosphamide (Cytoxan) and a non-steroidal anti-inflammatory medication (ie Piroxicam, Previcox, Deramaxx, Metacam).
Treatment of Canine Lymphoma Lymphoma is the canine tumor most frequently treated with chemotherapy. It is the most common hematopoietic neoplasia of dogs (see Canine Lymphoma) and cats and is also among the most responsive to chemotherapy. Four antineoplastic agents, vincristine, cyclophosphamide, doxorubicin, and prednisone, form the basis for many lymphoma treatment protocols. Treatments based on these four drugs are often abbreviated as CHOP (cyclophosphamide, hydroxydaunorubicin [doxorubicin], OncovinÂ® [a trade name of vincristine], and prednisone) protocols.