However, it is a known DNA mutagen, and this in turn could lead to carcinogenic effects. Acrolein has also been been linked with heart disease as a contributor, and is one of the most abundant chemicals in cigarette smoke.
1 Steroid hormones pass through the cell membrane of the target cell. 2  The steroid hormone binds with a specific receptor in the cytoplasm. 3  The receptor bound steroid hormone travels into the nucleus and binds to another specific receptor on the chromatin.teroid hormones cause changes within a cell by first passing through the cell membrane of the target cell. Steroid hormones, unlike non-steroid hormones, can do this because they are fat-soluble.
location of receptors, mechanism by which binding induces effect of hormone, varies. â¢ hydrophilic peptides, catecholamines, not able to pass â lipid membranes, bind with receptors on cell surface â¢ lipophilic steroids, thyroid hormone easily pass â surface membrane, bind with specific receptors inside target cell.teroid hormones. penetrate plasma membrane â¢ Bind to intracellular receptors-in cytoplasm or nucleus â¢ Hormone binding activates receptor-forms complexes with other proteins-binds to specific receptor sites (hormone response elements) on DNA to initiate protein synthesis-hormone then cleared from cell.