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Januvia Substitutes. If JanuviaÂ® (sitagliptin) is not working for you, or if it is causing bothersome side effects, you may want to ask your healthcare provider about substituting another medication. Several alternatives to Januvia are available for type 2 diabetes. These include other oral diabetes drugs, such as:
Given that Januvia costs $190 a month and glipizide costs $4 a month (on many pharmacy generic drug savings plans) it's worth taking a closer look at the statistics. Safety and Efficacy of Treatment with Sitagliptin or Glipizide in Patients with Type 2 Diabetes Inadequately Controlled on Metformin: A 2-year Study.