An IRB/IEC should have: 1  At least five members. 2  Members with varying backgrounds. 3  At least one member must represent a non-scientific area (a lay member) 4  At least one member must not be affiliated with the institution or the trial site (an independent member)
Vesicles and Vacuoles Vesicles and vacuoles are membrane-bound sacs that function in storage and transport. Vacuoles are somewhat larger than vesicles, and the membrane of a vacuole does not fuse with the membranes of other cellular components. Vesicles can fuse with other membranes within the cell system (Figure 1).
Vacuoles may also containsolutions of enzymes and occasionally solid particles that have been engulfed. There is no typical size or shape for a vacuole, theysimply vary depending on what the individual cell needs. They're formed by the fusion of several different vesicles. Vacuoles can serve a wide variety of functions in a cell, and their importance depends on what role they play within the cell.