However, some people who have early-onset Alzheimer's don't have mutations in these three genes. That suggests that this early-onset form of Alzheimer's disease is linked to other genetic mutations that haven't been identified yet.
Early history Cigars, cigarettes Cancer by the carton Legal history Surgeon General's warning. (CNN) -- Tobacco was first used by the peoples of the pre-Columbian Americas. Native Americans apparently cultivated the plant and smoked it in pipes for medicinal and ceremonial purposes.
Later, Shakespeare bought a signifcant tract of land in Stratford and made a significant profit from its resale. FAQ #22: What is The First Folio? The First Folio of 1623, compiled by Shakespeareâs close friends and fellow actors, John Hemminges and Henry Condell, was the first publication of Shakespeareâs plays.