An IRB/IEC should have: 1  At least five members. 2  Members with varying backgrounds. 3  At least one member must represent a non-scientific area (a lay member) 4  At least one member must not be affiliated with the institution or the trial site (an independent member)
Vesicles and Vacuoles Vesicles and vacuoles are membrane-bound sacs that function in storage and transport. Vacuoles are somewhat larger than vesicles, and the membrane of a vacuole does not fuse with the membranes of other cellular components. Vesicles can fuse with other membranes within the cell system (Figure 1).
The contractile vacuole enlarges as water enters then abruptly contracts, forcing the water out of the cell through a special pore structure. Vacuoles work with the cell membrane to move materials in and out of the cell. They also work with the lysosomes of a cell to digest cellular materials. Vesicle Vacuoles are basically vesicles filled with mostly water. A vesicle is a small bubble in a cell. This bubble is similar to a plasma membrane, consisting of a lipid bi-layer.