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Januvia Substitutes. If JanuviaÂ® (sitagliptin) is not working for you, or if it is causing bothersome side effects, you may want to ask your healthcare provider about substituting another medication. Several alternatives to Januvia are available for type 2 diabetes. These include other oral diabetes drugs, such as:
If you have problems with metformin then you will have the same ones with Janumet, it's a combo pill of Januvia and metformin. There is no other drug currently that does the same thing as Januvia although there are several ones in the pipeline and one undergoing FDA approval.