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The infusion time should not exceed 4 hours. Platelets, plasma and cryoprecipitate generally are transfused at a rate of 10 ml per minute. In order for a patient to receive maximum benefit platelets need to be transfused rapidly to get control of bleeding.
Determined on basis of baseline platelet count, desired platelet count, and estimated blood volume. For 70 kg patient, 4 x 10 11 platelets (about 4 units WB platelets or 1 apheresis platelet), platelet increment of approximately 30,000/ul is expected in the absence of alloimmunization or excessive consumption.