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The development of each chain is controlled at a separate genetic locus. Changes in the amino acid sequence of these chains results in abnormal hemoglobins. For example, hemoglobin S is found in sickle-cell disease, a severe type of anemia in which the red cells become sickle-shaped when oxygen is in short supply.
Hb, Hbg, Hgb. The iron-containing pigment of red blood cells (RBCs) that carries oxygen from the lungs to the tissues. The amount of hemoglobin in the blood averages 12 to 16 g/100 ml in women, 14 to 18 g/100 ml in men, and somewhat less in children.emoglobin releases the carboxyhemoglobin in the lungs for excretion and picks up more oxygen for transport to the cells. Also spelled haemoglobin. See also carboxyhemoglobin, complete blood count, differential white blood cell count, erythrocyte, erythropoiesis, heme, hemoglobinopathy, hemolysin, oxyhemoglobin.