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The infusion time should not exceed 4 hours. Platelets, plasma and cryoprecipitate generally are transfused at a rate of 10 ml per minute. In order for a patient to receive maximum benefit platelets need to be transfused rapidly to get control of bleeding.
Platelet transfusions are often ineffective in immune thrombocytopenic purpura (ITP) and should be reserved for patients with life- or limb-threatening bleeding, in which case platelets should be maintained above 50 x 109/L. Patients with ITP with a platelet count <10 x 109/L should be transfused only in the setting of serious bleeding.