1 People usually develop type 2 diabetes after age 45, but in recent years the average age of onset has been lower. 2  Type 2 is also starting to show up in children. 3  Gestational diabetes increases a woman's chance of developing type 2 diabetes later in life by almost 40 percent.ther risk factors to be aware of: 1  People usually develop type 2 diabetes after age 45, but in recent years the average age of onset has been lower. 2  Type 2 is also starting to show up in children. 3  Gestational diabetes increases a woman's chance of developing type 2 diabetes later in life by almost 40 percent.
Clinical Significance Statistical significance focuses on the null value of the effect. More important is clinical significance defined by the smallest clinically beneficial and harmful values of the effect. These values are usually equal and opposite in sign.
In clinical research is not only important to assess the significance of the differences between the evaluated groups but also it is recommended, if possible, to measure how meaningful the outcome is (for instance, to evaluate the effectiveness and efficacy of an intervention).tatistical significance does not provide information about the effect size or the clinical relevance. Because of that, researchers often misinterpret statistically significance as clinical one. On one hand, a large sample size study may have a statistically significant result but a small effect size.