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Januvia Substitutes. If JanuviaÂ® (sitagliptin) is not working for you, or if it is causing bothersome side effects, you may want to ask your healthcare provider about substituting another medication. Several alternatives to Januvia are available for type 2 diabetes. These include other oral diabetes drugs, such as:
Januvia is primarily used for the treatment of type 2 diabetes. It can either be used alone or with other anti-diabetic drugs like metformin or a thiazolidinedione. It is a DDP-4 inhibitor and therefore inhibits the growth of the dipeptidyl peptidase 4 enzyme. There are some studies being conducted which link DDP-4 inhibitors with an increased chance of getting cancer. The Januvia drug helps control blood sugar in the body by regulating insulin levels after intake of food.