After the transcription factor binds the DNA, co-regulatory molecules will bind the transcription factor. As with the DBD, transcription factors do not bind to just any co-regulatory proteins.The TAD region of the transcription factor interacts with co-regulatory proteins and it too, has unique sequences.These sequences are only recognized by certain co-regulatory proteins.n summary, transcription factors regulate gene expression. They do this by interacting directly with a target gene through the DBD. Once the transcription factor binds to DNA, co-regulatory molecules bind the transcription factor at the TAD.
In order to successfully stain a deck, the surface must be completely dry and clear of debris. Working on a sunny day with no forecast for rain, start by sweeping deck with broom. TIP: New decks simply need sweeping prior to staining.
1 For best results, avoid staining at midday or in direct sunlight. 2  If a second coat is required, wait 4 hours between applications. 3  Depending on temperature and humidity, allow 24 - 48 hours of dry time before using your beautifully restored deck or porch. Working with the wood grain, apply an even coat of stain using a 4-inch brush. 2  If available, you may also use a roller to first apply the stain, then work it into the wood with your brush. 3  For best results, avoid staining at midday or in direct sunlight. 4  If a second coat is required, wait 4 hours between applications.