However, some people who have early-onset Alzheimer's don't have mutations in these three genes. That suggests that this early-onset form of Alzheimer's disease is linked to other genetic mutations that haven't been identified yet.
Early history Cigars, cigarettes Cancer by the carton Legal history Surgeon General's warning. (CNN) -- Tobacco was first used by the peoples of the pre-Columbian Americas. Native Americans apparently cultivated the plant and smoked it in pipes for medicinal and ceremonial purposes.
The plant family Nicotiana and the word nicotine is named after Jean Nicot who brought tobacco seeds to Europe in 1560. He introduced snuff (tobacco that is inhaled) to the French court and from here the use of the product spread around Europe.owever, the tobacco that is most commonly grown as a cash crop today originated in the Americas where it had long been cultivated and used by the native people. Christopher Columbus was the first European to be introduced to the plant on his first voyage to the New World.