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From Wikipedia, the free encyclopedia. The urea cycle (also known as the ornithine cycle) is a cycle of biochemical reactions occurring in many animals that produces urea ((NH2)2CO) from ammonia (NH3). This cycle was the first metabolic cycle discovered (Hans Krebs and Kurt Henseleit, 1932), five years before the discovery of the TCA cycle. In mammals, the urea cycle takes place primarily in the liver, and to a lesser extent in the kidney.
The urea cycleA metabolic process in which waste (nitrogen) from the breakdown of proteins in the body is changed by the liver into urea, which is excreted in the urine. is part of the process that happens in the body to turn food into energy. Those amino acids are used to build muscle, skin, blood cells, and more. This is what helps you grow and remain healthy. However, the urea cycle turns the rest of itâwhat your body doesnât needâinto ammoniaA waste product of protein digestion that is removed by the urea cycle process. and other waste products.