What is it: A Process Control Plan (PCP) is a summary of defect prevention and reactive detection techniques. The overall intent of the PCP is to control the product characteristics and the associated process variables to ensure capability (around the identified target or nominal) and stability of the product over time.
Various compounds can reduce the activity of enzymes. They may act in a variety of different ways, and indeed may be reversible or irreversible inhibitors of the enzyme. An irreversible inhibitor causes covalent modification of the enzyme, so that its activity is permanently reduced.
Structural Biochemistry/Enzyme/Active Site - Irreversible Inhibitors. 1  Irreversible inhibitors covalently bind to an enzyme, cause chemical changes to the active sites of enzymes, and cannot be reversed. A main role of irreversible inhibitors include modifying key amino acid residues needed for enzymatic activity.