A weighted rein refers to a rein that is heavier on one or both ends. Naturally weighted reins are cut from hides that are specifically chosen for their weights and thicknesses. No extra leather or additional materials are added to the them. Notice in the picture the difference in the thicknesses of the tail, center and bit ends of this pair of reins.
Mitomycin C is a potent DNA crosslinker. A single crosslink per genome has shown to be effective in killing bacteria. This is accomplished by reductive activation of mitomycin to form a mitosene, which reacts successively via N-alkylation of two DNA bases.
Mitomycin is a cancer medication that interferes with the growth and spread of cancer cells in the body. Mitomycin is used in combination with other cancer medications to treat cancer of the stomach and pancreas. Mitomycin treats only the symptoms of stomach or pancreatic cancer but does not treat the cancer itself. Mitomycin may also be used for purposes not listed in this medication guide. Mitomycin can lower blood cells that help your body fight infections and help your blood to clot.