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Answers. Best Answer: Alprazolam (xanax) has a half life of 6 - 12 hours so half of the drug will be gone in about 9 hours and then it will be down to a quarter of your dose in 18 hours etc. It should be completely undetectable within 3 - 5 days.
How long do Xanax effects last. The effects of Xanax donât last long. Typically Xanax effects will only last a bout 4 hours. This is why itâs not always the drug of choice for treating chronic anxiety disorders.or example, other drug metabolize and leave the blood within a few hours; Xanax leaves the blood after several days. Furthermore, Xanax is detectable in urine for at least a week after last dose. With chronic or heavy use, Xanax can still be detected a month and a half after the last dose taken.