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Answers. Best Answer: Alprazolam (xanax) has a half life of 6 - 12 hours so half of the drug will be gone in about 9 hours and then it will be down to a quarter of your dose in 18 hours etc. It should be completely undetectable within 3 - 5 days.
Xanax doesnât clear the body as quickly as many other drugs. In fact, Xanax can be detectable in urine for up to 6 weeks in heavy users. Plus, the main ingredient in Xanax (alprazolam) takes a fairly long time to absorb once itâs in the body, so even small doses can be detectable for over a week.anax is absorbed quickly in the body and reaches its peak levels in the blood within one or two hours. These plasma blood levels vary depending on the dose taken, but range from 8-37 ng/mL. The half life of Xanax in healthy adults averages 11 hours. In elderly subjects the half life of Xanax is higher, about 16 hours.