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1. Polycystic Ovarian Syndrome (PCOS). This is one of the more common causes of high testosterone in women. Not only does this disease affect 5-10% of American women, it can also cause testosterone levels to skyrocket, resulting in a variety of symptoms.
In general, estradiol causes cells to proliferate and progesterone causes cells to differentiate and grow up. Estradiol causes the femaleness in women. It causes the breasts to grow and the hips to round out. However, too much estradiol can cause an increased incidence of breast cancer. Women who have menarche early and have menopause later are at a greater risk of breast cancer.