Research has demonstrated that many individuals with Crohnâs ileitis share a genetic mutation that may play a significant role in disease development. A hypersensitive immuno-response to a pathogenic presence, such as bacteria, within the gastrointestinal tract is also suspected of contributing to the disease's onset.
Secondary osteoarthritis occurs less frequently than primary (also known as idiopathic) osteoarthritis. Primary osteoarthritis means that there is no known cause for the joint breakdown.
osteoarthritis. a noninflammatory degenerative joint disease marked by degeneration of the articular cartilage, hypertrophy of bone at the margins, and changes in the synovial membrane.Primary osteoarthritis, as part of the normal aging process, is most likely to strike the joints that receive the most use or stress over the years.EDICAL: Bone Disease and Arthropathies With Major CC. Degenerative joint disease (DJD), or osteoarthritis, is a nonsystemic, noninflammatory, progressive disorder of movable joints that is associated with aging and accumulated trauma.