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Facilitated diffusion requires. enzymes. carrier proteins. lipid carriers. carbohydrate carriers. lipid or carbohydrate carriers. 2. Facilitated diffusion occurs. into the cell only. out of the cell only.
Often, they will change shape in response to binding of their target molecule, with the shape change moving the molecule to the opposite side of the membrane. The carrier proteins involved in facilitated diffusion simply provide hydrophilic molecules with a way to move down an existing concentration gradient (rather than acting as pumps).