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1. Polycystic Ovarian Syndrome (PCOS). This is one of the more common causes of high testosterone in women. Not only does this disease affect 5-10% of American women, it can also cause testosterone levels to skyrocket, resulting in a variety of symptoms.
The exact cause of the age-related reduction in testosterone levels is not known; it is probably the result of a combination of factors, including: 1  Increasing body fat (especially belly fat, and therefore increasing aromatase activity). 2  Oxidative damage to tissues responsible for the production of testosterone.