What is canavan disease? Canavan deteriorates the white matter (myelin) in the brain. White  matter is responsible for forming a protective coating around every  nerve in the brain and spinal cord tâ¦o ensure that nerve impulses  are properly transmitted from one part of the body to another.
Pruning Knock OutÂ® Roses. June 12th, 2013. Prune your rose bush in early spring, never in the fall and never in the winter. Check your rose bush from time to time as spring moves along and when you start to see new shoots growing from the canes on your rose bush, thatâs a good sign that it is time to prune.
A common question with these roses is, âDo I need to prune Knock Out roses?â The short answer is that you donât need to, but they will perform better if you do some pruning. Letâs look at what goes into pruning Knock Out roses. Pruning Tips for Knock Out Roses When it comes to pruning Knock Out rose bushes, I recommend the best time when to prune Knock Out roses is in the early spring just as with any other rose bushes. Prune out the broken canes from the winter snows or wind whipping of the bushes.