Kuali Financial System. Become a KFS User. Make sure you have an Acceptable Use Agreement on file. If you have not completed one before, you can do so at: http://protect.iu.edu/agreement. Your department must submit a KFS System User Role document, located in the Chart of Accounts module of KFS.
A change in. the content of the genetic messageâthe base sequence of. one or more genesâis referred to as a mutation. Some mu-. tations alter the identity of a particular nucleotide, while. others remove or add nucleotides to a gene.
A gene mutation is a permanent alteration in the DNA sequence that makes up a gene, such that the sequence differs from what is found in most people. Mutations range in size; they can affect anywhere from a single DNA building block (base pair) to a large segment of a chromosome that includes multiple genes.or example, some mutations alter a geneâs DNA sequence but do not change the function of the protein made by the gene. Often, gene mutations that could cause a genetic disorder are repaired by certain enzymes before the gene is expressed and an altered protein is produced.