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Diverticular Disease. Definition & Facts. Diverticulosis is a condition that occurs when small pouches, or sacs, form and push outward through weak spots in the wall of your colon. In diverticulitis, one or a few of the pouches in the wall of your colon become inflamed.
Diverticulosis indicates the presence of multiple diverticula and generally implies an absence of symptoms (Fig. 1). Diverticular disease implies any clinical state caused by diverticula, including hemorrhage, inflammation, or their complications.Diverticulitis describes the presence of an inflammatory process associated with diverticula. Its pathogenesis is attributed to genetic and environmental factors (Box 1).he fiber content of the diet plays a large role in the pathogenesis of diverticular disease. Fiber has been found to be protective. Most fiber in the human diet is of plant origin and this type of fiber binds water and salt in the colon, leading to bulkier and more voluminous stools.