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A biopsy is the only way to diagnose non-Hodgkin lymphoma. There are several types of biopsies. Doctors choose which one to use based on each personâs situation. Excisional or incisional biopsy: This is the most common type of biopsy if lymphoma is suspected.any symptoms of non-Hodgkin lymphoma are not specific enough to say for certain if they are being caused by cancer. Most of them can also be caused by non-cancerous problems, like infections, or by other kinds of cancers.
Tests, investigations and surgery. Various tests are used to diagnose lymphoma and to assess its aggressiveness and spread. While initial tests may reveal lymphoma, further tests may be needed to determine which of several types of Hodgkin or non-Hodgkin lymphoma it is. Patients with lumps or enlarged lymph nodes usually have a biopsy.