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Answers. Best Answer: Alprazolam (xanax) has a half life of 6 - 12 hours so half of the drug will be gone in about 9 hours and then it will be down to a quarter of your dose in 18 hours etc. It should be completely undetectable within 3 - 5 days.
In order to address your particular concerns and questions regarding this medication, I recommend that you schedule an appointment to speak with your doctor, so that he or she can address your individual case. Having said that, the average half-life of xanax is approximately 11 hours. This means that half of the medication will have left the body by that time. On the other hand, it is important to note that everyone metabolizes medications differently, so this half-life can range from 6 to 26 hours, depending on the person and the dose and frequency of the use of the medication.