Signs of physical and emotional exhaustion: 1  Chronic fatigue. 2  In the early stages, you may feel a lack energy and feel tired most days. 3  In the latter stages, you feel physically and emotionally exhausted, drained, and depleted, and you may feel a sense of dread for what lies ahead on any given day. 4  Insomnia.
Clinical Trials. Itraconazole is effective and safe in the treatment of vulvovaginal candidiasis 8-15 (see Table 1). Treatment regimens of itraconazole 200mg/day for 3 consecutive days 8,9,11 or 200mg given twice in one day 9,12,14 have resulted in a high mycological and clinical cure.able 1: Studies evaluating the efficacy of itraconazole in the treatment of vulvovaginal candidiasis. Table 2: Studies evaluating the efficacy of itraconazole in the prophylactic treatment of vulvovaginal candidiasis.
One such study was done on 20 patients to assess the therapeutic efficacy of itraconazole in vaginal candidiasis. 15 In this study, an oral dose of itraconazole 100mg was given twice a day once a week for three consecutive weeks.After receiving the treatment, only 45% patients had mild itching and burning.onclusion: Itraconazole was found to be more effective in the treatment of vulvovaginal candidiasis compared to fluconazole with high cure and low relapse rate. Keywords: Itraconazole, Fluconazole, Vaginal candidiasis, Efficacy. (JPMA 62: 1049; 2012).