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The vagus nerve (/ËveÉªÉ¡És/ VAY-gÉs), historically cited as the pneumogastric nerve, is the tenth cranial nerve or CN X, and interfaces with parasympathetic control of the heart, lungs and digestive tract. The vagus nerves are paired; however, they are normally referred to in the singular.
Parasympathetic (vagal) nerves leave the vagal nuclei within the medulla as preganglionic efferent vagal fibers. These preganglionic efferent fibers are relatively long and do not synapse until they reach their target organ (e.g., the heart).