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The most common Topamax side effects when taken alone by children aged 10 to 16 with epilepsy are: 1  Weight loss. 2  Upper respiratory tract infection. 3  Tingling of the arms and legs.  A loss of appetite 1  (anorexia) Diarrhea.  Mood problems.
Weight-Loss Success. Weight loss was one of the most common side effects of Topamax, occurring in between 11 and 26 percent of patients taking the drug. According to Ortho-McNeil's Topamax website, some patients lose weight while taking Topamax, and the amount of weight loss varies according to the dosage taken.