Research has demonstrated that many individuals with Crohnâs ileitis share a genetic mutation that may play a significant role in disease development. A hypersensitive immuno-response to a pathogenic presence, such as bacteria, within the gastrointestinal tract is also suspected of contributing to the disease's onset.
Secondary osteoarthritis occurs less frequently than primary (also known as idiopathic) osteoarthritis. Primary osteoarthritis means that there is no known cause for the joint breakdown.
Osteoarthritis (OA) is a chronic disease process affecting synovial joints, particularly large weight-bearing joints.OA is particularly common in older patients but can occur in younger patients either through a genetic mechanism or, more commonly, because of previous joint trauma.steoarthritis (OA) is a chronic disease process affecting synovial joints, particularly large weight-bearing joints.