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Answers. Best Answer: Alprazolam (xanax) has a half life of 6 - 12 hours so half of the drug will be gone in about 9 hours and then it will be down to a quarter of your dose in 18 hours etc. It should be completely undetectable within 3 - 5 days.
That is, after this length of time, one half of the taken dose is still present in your system. After another 6 to 12 hours, a half of this half is still present, and so on. <br /> How long Xanax will stay in your system cannot be predicted for sure.