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Doxycycline is the drug of choice for Rocky Mountain spotted fever (RMSF). It inhibits protein synthesis and, consequently, bacterial growth by binding to 30S and possibly 50S ribosomal subunits of susceptible bacteria.
The Symptoms Early symptoms of Rocky Mountain spotted fever, which start 2 to 14 days after the tick bite, include fever, deep muscle pain, severe headache, chills, and upset stomach or vomiting.Around the third day a red, spotted rash usually appears, beginning on the wrists and ankles.he Symptoms Early symptoms of Rocky Mountain spotted fever, which start 2 to 14 days after the tick bite, include fever, deep muscle pain, severe headache, chills, and upset stomach or vomiting.