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Doxycycline is the drug of choice for Rocky Mountain spotted fever (RMSF). It inhibits protein synthesis and, consequently, bacterial growth by binding to 30S and possibly 50S ribosomal subunits of susceptible bacteria.
Types of ticks. Rocky Mountain spotted fever is caused by infection with the organism Rickettsia rickettsii. Ticks carrying R. rickettsii are the most common source of infection. If an infected tick attaches itself to your skin and feeds on your blood for six to 10 hours, you may pick up the infection.ocky Mountain spotted fever is caused by infection with the organism Rickettsia rickettsii. Ticks carrying R. rickettsii are the most common source of infection.