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Answer Wiki. One unit of packed red blood cells (PRBC) contains about 180 ml of actual RBC, and is 310 ml total (270-350 ml). PRBC will typically have a hematocrit of 57-58% (50-65%). (The unit of PRBC usually also still contains 30 ml of plasma (without coagulants), and 100 ml of Optisol.
That said, while most units of PRBCs run 325-375 mLs, I have had units with as little as 200mLs and as large 575mLs. Platelets vary even more. There are pheresis units vs pooled platelets (with from 4-9 units in a bag), washed platelets-the volume can vary between 150mLs for washed platelets to 600mLs for regular.