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Answers. Best Answer: Alprazolam (xanax) has a half life of 6 - 12 hours so half of the drug will be gone in about 9 hours and then it will be down to a quarter of your dose in 18 hours etc. It should be completely undetectable within 3 - 5 days.
Xanax duration of action. The half-life of Xanax is a lengthy 11 hours. Xanax reaches peak levels in the blood within 2 hours. However, despite taking several days to leave the body, the effects of Xanax tend to wear off after about 4 hours, so it may need to be taken several times throughout the day. How long Xanax stays in the body is rather long, relative to other drugs.