What is canavan disease? Canavan deteriorates the white matter (myelin) in the brain. White  matter is responsible for forming a protective coating around every  nerve in the brain and spinal cord tâ¦o ensure that nerve impulses  are properly transmitted from one part of the body to another.
Pruning Knock OutÂ® Roses. June 12th, 2013. Prune your rose bush in early spring, never in the fall and never in the winter. Check your rose bush from time to time as spring moves along and when you start to see new shoots growing from the canes on your rose bush, thatâs a good sign that it is time to prune.
Pruning Knockout Roses Pruning Tips. Start by giving the Knockout an overall pruning and grooming to give it a pleasing and attractive shape. When doing Knockout rose bush pruning, it's good to cut down the plant by 1/3 to 1/2, to ensure optimum flower production. If your knockouts tend to grow very tall, you could actually be more agressive when pruning, to about a foot off the ground.