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Several vaccines are available to help prevent disease caused by Borrelia burgdorferi, the Lyme disease organism. An initial vaccination is followed by a booster vaccine 2 to 4 weeks later (in accordance with label recommendations) and annual boosters as long as the risk for disease exposure remains. Even dogs that receive year-round tick control products and donât spend a lot of time outside may be at risk for exposure to tick-borne diseases. 2  The Lyme disease vaccine helps prevent disease caused by Borrelia burgdorferi, the Lyme disease organism.
3) Vaccination for Lyme disease. We have a highly effective Lyme vaccine that can be given to pets 9 weeks and older. Although some studies indicate our Lyme vaccine is nearly 100% efficacious, we also recommend using a tick prevention product as outlined above.revious vaccination for Lyme disease does not interfere with these test results (a vaccinated dog will not be positive for Lyme simply because it has received the Lyme vaccine in the past). It takes a few weeks from the time of exposure for the development of a positive antibody Lyme test.