Residents of the District of Columbia lack full democratic representation in the U. S. Senate or the U.S. House of Representatives. Representation in Congress is limited to a non-voting delegate to the House of Representatives and a shadow Senator.
Huntington's disease is a progressive brain disorder caused by a single defective gene on chromosome 4 â one of the 23 human chromosomes that carry a personâs entire genetic code. This defect is dominant, meaning that anyone who inherits it from a parent with Huntington's will eventually develop the disease.
Huntington's disease (HD) is caused by a mutated form of the huntingtin gene, where excessive (more than 36) CAG repeats result in formation of an unstable protein. These expanded repeats lead to production of a huntingtin protein that contains an abnormally long polyglutamine tract at the N-terminus.