Kuali Financial System. Become a KFS User. Make sure you have an Acceptable Use Agreement on file. If you have not completed one before, you can do so at: http://protect.iu.edu/agreement. Your department must submit a KFS System User Role document, located in the Chart of Accounts module of KFS.
A change in. the content of the genetic messageâthe base sequence of. one or more genesâis referred to as a mutation. Some mu-. tations alter the identity of a particular nucleotide, while. others remove or add nucleotides to a gene.
The mutation changes the gene's instructions for making a protein, so the protein does not work properly or is missing entirely. This can cause a medical condition called a genetic disorder. You can inherit a gene mutation from one or both parents. A mutation can also happen during your lifetime. There are three types of genetic disorders: 1  Single-gene disorders, where a mutation affects one gene. 2  Chromosomal disorders, where chromosomes (or parts of chromosomes) are missing or changed. 3  Complex disorders, where there are mutations in two or more genes.