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The most common Topamax side effects when taken alone by children aged 10 to 16 with epilepsy are: 1  Weight loss. 2  Upper respiratory tract infection. 3  Tingling of the arms and legs.  A loss of appetite 1  (anorexia) Diarrhea.  Mood problems.
Hi The abnormal metallic taste sensation or taste perversion is a common side effect seen after Topamax use. These tablets have a bitter taste and lose their effectiveness quickly when broken, so you should swallow them whole. Chewing the tablet may leave a bitter taste. Hence, do not split, chew, or crush them.