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The most common Topamax side effects when taken with other medicines by children with epilepsy are: 1  Fatigue. 2  Sleepiness. 3  Lack of appetite (anorexia) 4  Nervousness. Problems concentrating or paying attention.  Memory 1  problems. Aggressiveness.  Weight loss.
The most common side effects associated with Topamax include sleepiness, dizziness, fatigue, nervousness, incoordination and unsteadiness, slowing of movement, speech problems, memory difficulties, behavior problems, confusion, difficulty concentrating, depression, decrease in blood bicarbonate levels, loss of appetite, nausea, weight loss, tingling, pricking, or numbness of the skin, abnormal vision, abnormal eye movements, upper respiratory tract infection, and injury.