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Answers. Best Answer: Alprazolam (xanax) has a half life of 6 - 12 hours so half of the drug will be gone in about 9 hours and then it will be down to a quarter of your dose in 18 hours etc. It should be completely undetectable within 3 - 5 days.
Posts. 30. It will take about 4 half-lives to get a drug out of your system. xanax is around 12 hours so figure 2 days. but it depends on how much you take, how good your liver is at clearing and how sensitive the test is. it also matters what time of day you take test and how much water you drink and void out first.