Kuali Financial System. Become a KFS User. Make sure you have an Acceptable Use Agreement on file. If you have not completed one before, you can do so at: http://protect.iu.edu/agreement. Your department must submit a KFS System User Role document, located in the Chart of Accounts module of KFS.
A change in. the content of the genetic messageâthe base sequence of. one or more genesâis referred to as a mutation. Some mu-. tations alter the identity of a particular nucleotide, while. others remove or add nucleotides to a gene.
A change to the DNA in a gene can alter a protein's amino acid sequence, thereby changing its shape and function and rendering the protein ineffective or even malignant (e.g. sickle cell anemia). Changes to genes are called mutations. single 'gene' is most similar to a single 'word' in the English language. The nucleotides (molecules) that make up genes can be seen as 'letters' in the English language. Nucleotides are named according to which of the four nitrogenous bases they contain. The four bases are cytosine, guanine, adenine, and thymine.