Signs of physical and emotional exhaustion: 1  Chronic fatigue. 2  In the early stages, you may feel a lack energy and feel tired most days. 3  In the latter stages, you feel physically and emotionally exhausted, drained, and depleted, and you may feel a sense of dread for what lies ahead on any given day. 4  Insomnia.
Clinical Trials. Itraconazole is effective and safe in the treatment of vulvovaginal candidiasis 8-15 (see Table 1). Treatment regimens of itraconazole 200mg/day for 3 consecutive days 8,9,11 or 200mg given twice in one day 9,12,14 have resulted in a high mycological and clinical cure.able 1: Studies evaluating the efficacy of itraconazole in the treatment of vulvovaginal candidiasis. Table 2: Studies evaluating the efficacy of itraconazole in the prophylactic treatment of vulvovaginal candidiasis.
The women were enrolled prospectively in separate, sequential, nonrandomized clinical trials and treated with nystatin vaginal suppository at 20 MU per day for 7 days or two 1,200-mg doses of miconazole vaginal suppositories 72 hours apart or oral fluconazole two 150-mg doses 72 hours apart or oral itraconazole 200 mg two times for 1 day.