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Answers. Best Answer: Alprazolam (xanax) has a half life of 6 - 12 hours so half of the drug will be gone in about 9 hours and then it will be down to a quarter of your dose in 18 hours etc. It should be completely undetectable within 3 - 5 days.
Xanax has an elimination half-life that ranges from 9 hours to 16 hours in healthy adults. This means that it will take most people within the span of 9 to 16 hours (post-ingestion) to eliminate 50% of the drug from their body. On average (among most users), the half-life of Xanax is around 12 hours. This means that most people will have fully eliminated (100%) the drug from their system within 4 days.