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Antibiotics for Ear Infections: An Overview Many antibiotics are approved by the Food and Drug Administration (FDA) to fight otitis media (ear infections), although most doctors rely on a few favorites. Most antibiotics for ear infections fall under four families:  penicillins, cephalosporins, sulfonamides, and erythromycins. Amoxicillin is the most common antibiotic used to treat ear infections. When using antibiotics for ear infections, remember to take each dose on schedule.
Ciprodex is a medication used to treat bacterial ear infections. Ciprodex contains a quinolone-type antibiotic (ciprofloxacin) and a steroid (dexamethasone). This medication is prepared as ear drops. Ciprodex is a brand version of the combination drug ciprofloxacin HCL/dexamethasone. The components of this drug have been available for years. In the treatment of ear infections, Ciprodex use is common.