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The Missouri Compromise of 1820 was important because it played a significant role in the relationship between the North and the South. It resulted in the admission of Missouri to the Union as a slave state.he Missouri Compromise of 1820 admitted Missouri as a slave state,  and Maine as a free state, to keep the balance of slave/non-slave  states equal in Congress.
Henry Clay, a leading congressman, played a crucial role in brokering a two-part solution known as the Missouri Compromise. First, Missouri would be admitted to the union as a slave state, but would be balanced by the admission of Maine, a free state, that had long wanted to be separated from Massachusetts. Second, slavery was to be excluded from all new states in the Louisiana Purchase north of the southern boundary of Missouri. People on both sides of the controversy saw the compromise as deeply flawed.