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The Missouri Compromise of 1820 was important because it played a significant role in the relationship between the North and the South. It resulted in the admission of Missouri to the Union as a slave state.he Missouri Compromise of 1820 admitted Missouri as a slave state,  and Maine as a free state, to keep the balance of slave/non-slave  states equal in Congress.
The Missouri Compromise was a United States federal statute devised by Henry Clay. It regulated slavery in the country's western territories by prohibiting the practice in the former Louisiana Territory north of the parallel 36Â°30â² north, except within the boundaries of the proposed state of Missouri.he United States in 1819 (the light orange and light green areas were not then part of the United States). The Missouri Compromise prohibited slavery in the unorganized territory of the Great Plains (upper dark green) and permitted it in Missouri (yellow) and the Arkansas Territory (lower blue area).