Related Content: Abstract: Efficient tools for profiling DNA methylation in specific genes are essential for epigenetics and clinical diagnostics. Current DNA methylation profiling techniques have been limited by inconvenient implementation, requirements of specific reagents, and ...
Autosomal Trisomy Chromosome Diseases. The 22 non-sex autosome chromosomes (autosomes) can also exhibit disorders, of which the most common is trisomy (having 3 copies rather than a pair). Because these are disorders of the autosomes and not the sex chromosomes, these disorders can occur with males or females.
Sex-linked disorders. Genetic diseases or conditions caused by a mutation on the sex chromosomes. Patterns of inheritance tend to be gender-specific. Single gene disorders. Genetic diseases or conditions caused by a mutation in a single gene or DNA sequence. Also known as Mendelian, Classical and Monogenic disorders.They are usually passed from one generation to the next. Somatic cells. Non-sex cells (not ova or sperm).Somatic or sporadic mutation.he predicted course and outcome of a disease. Recessive disorders. Genetic disease or condition caused by a mutation on both genes in a pair (homozygous). The disease or condition only arises when both parents pass on a copy of the faulty gene.