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Uday Devgan, M.D. T opical steroid use can have certain unwanted side effects. The main risks are a rise in intraocular pressure (IOP), posterior subcapsular cataracts, and increased infection.Increased pressure is a serious problem, as it could inadvertently give patients glaucoma.day Devgan, M.D. T opical steroid use can have certain unwanted side effects. The main risks are a rise in intraocular pressure (IOP), posterior subcapsular cataracts, and increased infection.
Then I had THE WORST breakout of my life. Being on prednisone has such bad side effects.. among the others listed by the person above, it can cause diabetes, glaucoma, weight gain, appitite increase, sleeplessness (the list goes on)... with long-term use. To me, it simply isnt worth it for moderate acne.