The TARDBP gene provides instructions for making a protein called transactive response DNA binding protein 43 kDa (TDP-43). This protein is found within the cell nucleus in most tissues and is involved in many of the steps of protein production.
(CNN)Sookie St. James, say it isn't so! Superstar comedian Melissa McCarthy says she wasn't asked to return to the Netflix revival of Gilmore Girls, the show on which she played the super-talented chef sidekick to Lauren Graham's character, Lorelai Gilmore. McCarthy may be the best-known graduate of Gilmore Girls, which premiered in 2000 and aired for seven years.
'Gilmore Girls' Scott Patterson on the Future of Luke and Lorelai. I had to take a walk around Stars Hollow and re-live things and smell it and sense it and feel it.. When Gilmore Girls ended in 2007, Scott Patterson didn't feel finished with the show. The actor, who played grouchy diner owner Luke Danes for seven seasons, actively campaigned to reboot the series after its conclusion. I was very, very determined to bring it back, Patterson told ELLE.com at Entertainment Weekly's pre-Emmy bash last night.