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Quantitation of changes in cell shape using computerized image analysis demonstrated that PDGF doubled the total projected area of lamellipodia formed by each cell within 5 min of addition and increased it by almost 10-fold at 30 min (Fig. 3 â A).o determine relative changes in lamellipodia length in different regions of the cell, corners were defined as parts of the square perimeter within 6 Î¼m from the intersection of the two sides; sides were defined as the 18 Î¼m interval between these corner regions.
Pseudopodia are formed by microtubule and filament structures. The cell surface projects a membrane process called the lamellipodium, which is supported inside by filaments that form at the leading edge, turning into networks as they merge. Cytoplasm flows into the lamellipodium, forming the pseudopodia.t is supposed that actin polymerization is at the origin of the force propelling the cell forward. Pseudopodia (false foot) are temporary cytoplasm-filled projections of the cell membrane that certain eukaryotic cells use for motion or for ingesting nutrients.