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The Missouri Compromise of 1820 was important because it played a significant role in the relationship between the North and the South. It resulted in the admission of Missouri to the Union as a slave state.he Missouri Compromise of 1820 admitted Missouri as a slave state,  and Maine as a free state, to keep the balance of slave/non-slave  states equal in Congress.
The Missouri Compromise was put forth by Senator Henry Clay in an attempt to prevent the addition of the new territory of Missouri, as a slave slate, from tipping the balance â¦ of power in Congress to Southern States.