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Haptoglobin, bilirubin, and liver function tests. When red blood cells break down, they release hemoglobin into the bloodstream. The hemoglobin combines with a chemical called haptoglobin. A low level of haptoglobin in the bloodstream is a sign of hemolytic anemia.
Hi Anjum, Unfortunately kidney disease can cause low hemoglobin levels when all those elements you mentioned are in the optimum range (B6, B12, folic acid, iron, etc). This is because the kidneys produce a hormone called erythropoietin (EPO), which signals the bone marrow to produce red blood cells.