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Hemolytic disease of the newborn (HDN) is a disease in which there is hemolysis in a newborn or fetus caused by blood-group incompatibility between mother and child. There are a bunch of related terms: Immune hydrops (Hydrops means accumulation of edema fluid in the fetus during intrauterine growth.
Updated April 13, 2016. Hemolytic Disease of the Newborn (HDN) is a condition of red blood cell mismatch between a mother and her baby. This occurs when the mother's blood type is Rh negative and the baby is Rh positive. During the pregnancy the mother produces antibodies that attack and destroy red blood cells, resulting in anemia in the fetus.