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Uday Devgan, M.D. T opical steroid use can have certain unwanted side effects. The main risks are a rise in intraocular pressure (IOP), posterior subcapsular cataracts, and increased infection.Increased pressure is a serious problem, as it could inadvertently give patients glaucoma.day Devgan, M.D. T opical steroid use can have certain unwanted side effects. The main risks are a rise in intraocular pressure (IOP), posterior subcapsular cataracts, and increased infection.
Common side effects with long-term use include osteoporosis, cataracts, weakness, easy bruising, and yeast infections. Short-term use around the time of delivery is safe for the baby; however, long-term use during pregnancy may result in harm. Methylprednisolone is in the glucocorticoid family of medication.