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Approximate Cost of Botox for migraine. The cost of a 100 unit vial of Botox is approximately $525. Note that a typical dose of Botox for migraine treatment is 155 units.
People who get migraines or chronic headaches that last for at least four hours and occur 15 or more days out of the month may be recommended for Botox treatment. In most cases, patients who have chosen to receive the injections experience dramatic relief.