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Oral thrush is the most common reason to use Diflucan for infants. Back to list. What is the Diflucan Infants Dosage? For oral thrush (oral candidiasis): The dose of Fluconazole is 6 mg/kg/day for the first dose and then 3 mg/kg/day for further doses. The whole course should last at least 7 days and can be given for up to 2 weeks. A 3.5 kg (about 7 1/2 pounds - 8 pounds) baby would need about 20 mg as the first dose (given just once in the day) and for the next 6-13 days would need 10 mg a day (given just once). The Diflucan oral solution comes as 40mg/ml so 20 mg is 0.5 ml and 10 mg is 0.25 ml.
Quick Answer. Fluconazole, or Diflucan, begins to work in one to three days, and symptoms may take up to seven days to completely disappear, according to C-Health from MediResource. Fluconazole, sold and marketed by Pfizer, is an oral antifungal medication that treats vaginal yeast infections with 150-milligram doses.