Norepinephrine is synthesized from dopamine by dopamine Î²-hydroxylase.[7] It is released from the adrenal medulla into the blood as a hormone, and is also a neurotransmitter in the central nervous system and sympathetic nervous system where it is released from noradrenergic neurons. The actions of norepinephrine are carried out via the binding
Insomnia symptoms may include: 1  Difficulty falling asleep at night. 2  Waking up during the night. 3  Waking up too early.  Not feeling well-rested after a night's 1  sleep. Daytime tiredness or sleepiness.  Irritability, depression or 1  anxiety. Difficulty paying attention, focusing on tasks or remembering.  Increased errors or accidents.
The four major signs and symptoms of narcolepsy are extreme daytime sleepiness, cataplexy (muscle weakness) while awake, and hallucinations and sleep paralysis during sleep. If you have narcolepsy, you may have one or more of these symptoms. They can range from mild to severe.