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Your feet and legs swell when fluid builds up in the space between the cells of your body. There are many reasons this can happen, some quite serious and many minor or transient. You should consult your doctor to determine the cause of your swelling, which you may hear referred to as edema.
Make sure to talk to your doctor if you suspect that your medication is causing swelling in your lower extremities. Donât stop taking your medication until you speak with your doctor. Other possible causes for foot, leg, and ankle swelling include certain medical conditions or body changes, such as: Natural hormonal changes: Fluctuating levels of estrogen and progesterone can cause reduced circulation in the legs, resulting in swelling.