There was a significant delay in time to clinical worsening in the bosentan-treated group (hazard ratio 0.227, P = .0114) as shown in the Figure, a finding largely driven by a reduction in progression of symptomatic PAH in the bosentan-treated group (1%) vs the placebo group (10%).
Trading, on the other hand, involves the more frequent buying and selling of stock, commodities, currency pairs or other instruments, with the goal of generating returns that outperform buy-and-hold investing. While investors may be content with a 10 to 15% annual return, traders might seek a 10% return each month.
DEFINITION of 'Trade'. A basic economic concept that involves multiple parties participating in the voluntary negotiation and then the exchange of one's goods and services for desired goods and services that someone else possesses.he advent of money as a medium of exchange has allowed trade to be conducted in a manner that is much simpler and effective compared to earlier forms of trade, such as bartering. In financial markets, trading also can mean performing a transaction that involves the selling and purchasing of a security.