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Photo Credit Jupiterimages/Comstock/Getty Images. Vitamin B-12 can be good for anxiety if you have a B-12 deficiency. If you have a poor diet, are a vegetarian, are older than 50, or if you have celiac disease or Crohnâs disease, you are more likely to have a B-12 deficiency than the rest of the population.hoto Credit Jupiterimages/Comstock/Getty Images. Vitamin B-12 can be good for anxiety if you have a B-12 deficiency. If you have a poor diet, are a vegetarian, are older than 50, or if you have celiac disease or Crohnâs disease, you are more likely to have a B-12 deficiency than the rest of the population.
The main causes of vitamin B12 deficiency include vitamin B12 malabsorption from food, pernicious anemia, postsurgical malabsorption, and dietary deficiency [ 12 ]. However, in many cases, the cause of vitamin B12 deficiency is unknown. The following groups are among those most likely to be vitamin B12 deficient.itamin B12 deficiency is characterized by megaloblastic anemia, fatigue, weakness, constipation, loss of appetite, and weight loss [ 1, 3, 27 ]. Neurological changes, such as numbness and tingling in the hands and feet, can also occur [ 5, 28 ].