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Approximate Cost of Botox for migraine. The cost of a 100 unit vial of Botox is approximately $525. Note that a typical dose of Botox for migraine treatment is 155 units.
Botox Common Migraine Treatment. Best known as a cosmetic therapy to banish facial frown lines, botulinum toxin type A, or Botox, was approved to prevent migraines in 2010, but only for patients who experience 15 or more migraine headaches a month.mong chronic sufferers who had at least 15 migraines a month, the treatment prevented, on average, about two headaches a month. Botox was no more effective than some of the most widely prescribed drugs used for migraines when the treatments were compared.