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The Missouri Compromise of 1820 was important because it played a significant role in the relationship between the North and the South. It resulted in the admission of Missouri to the Union as a slave state.he Missouri Compromise of 1820 admitted Missouri as a slave state,  and Maine as a free state, to keep the balance of slave/non-slave  states equal in Congress.
What does the Missouri compromise have to do with slavery? Missouri wanted to become a state in the US, but wanted slavery to be legal there. If they did so, it meant that there would be 2 more senators and then more representatives iâ¦n Congress that came from a slave state. Up to that point, Congress was split evenly between slave and free members.