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The Missouri Compromise of 1820 was important because it played a significant role in the relationship between the North and the South. It resulted in the admission of Missouri to the Union as a slave state.he Missouri Compromise of 1820 admitted Missouri as a slave state,  and Maine as a free state, to keep the balance of slave/non-slave  states equal in Congress.
March 3, 1820: Missouri Compromise. The Missouri Compromise was the first major legislative compromise passed to settle the slavery issue by drawing a line between slave and free territory. Speaker of the House Henry Clay promoted the deal, which admitted Maine to the Union as a free state and Missouri as a slave state.