NLG919 is a potent IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor with Ki/EC50 of 7 nM/75 nM in cell-free assays.NCB024360 analogue is a potent, competitive IDO1 (indoleamine-(2,3)-dioxygenase) inhibitor with IC50 of 67 nM. Phase 2. S7756. Indoximod (NLG-8189ï¼. Indoximod (NLG-8189), a methylated tryptophan, acts as an IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor, and reverses IDO-mediated immune suppression.
Other symptoms of a cold can include: 1  Stuffy nose (nasal congestion) 2  Sore throat. 3  Cough. Headache.  Slight body aches.
Signs and symptoms of common cold vs. flu. Common symptoms of the flu include fever, cough, sore throat, runny or stuffy nose, muscle or body aches, headaches, fatigue, and in some cases nausea, vomiting, and diarrhea.