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Although many medications are used in Advanced life support, the only medication with proven efficacy in pediatric resuscitation is epinephrine. Despite numerous investigations, the optimal dose remains controversial.
Alteplase is approved for the management of occluded catheters in children and infants.[ In the Cathflo Activase Pediatric Study (CAPS), 310 patients between the ages of 2 weeks and 17 years with a weight distribution of 2.2â107 kg were treated for central venous catheter occlusion (see Dosage).