The TARDBP gene provides instructions for making a protein called transactive response DNA binding protein 43 kDa (TDP-43). This protein is found within the cell nucleus in most tissues and is involved in many of the steps of protein production.
Jess Mariano is a recurring character on CW drama Gilmore Girls. He is portrayed by Milo Ventimiglia. Jess is the troubled love-interest of Rory Gilmore, son of Liz Danes and Jimmy Mariano, and nephew of Luke Danes. Jess is incredibly smart, quick-witted, and interested in the arts, but not academically motivated.
Emily Gilmore, played by Kelly Bishop, is the mother of Lorelai and grandmother to Rory. Emily had very limited contact with her daughter for most of her adult life, and though they have gotten to know each other better as adults, they still have a somewhat strained relationship.