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Causes. Wheezing results from a narrowing of the airways and typically indicates some difficulty breathing. The narrowing of the airways can be caused by inflammation from asthma, an infection, an allergic reaction, or by a physical obstruction, such as a tumor or a foreign object that's been inhaled.he most common cause of recurrent wheezing is asthma. Possible causes of wheezing include: 1  Allergies. 2  Anaphylaxis (a severe allergic reaction, such as to an insect bite or medication). 3  Asthma.
While wheezing most often is caused by an obstruction or narrowing of the small bronchial tubes in the chest, it can also be caused by an obstruction in the larger airways or vocal chords. Wheezing is most obvious when a person is breathing out (exhaling), but can also be heard when breathing in (inhaling).he causes of wheezing widely vary. They range from chronic, usually manageable conditions such as asthma to very serious conditions that include heart failure. The most common causes of wheezing include: 1  Asthma (a chronic respiratory condition that causes spasms in the bronchial tubes).