The TARDBP gene provides instructions for making a protein called transactive response DNA binding protein 43 kDa (TDP-43). This protein is found within the cell nucleus in most tissues and is involved in many of the steps of protein production.
(CNN)Sookie St. James, say it isn't so! Superstar comedian Melissa McCarthy says she wasn't asked to return to the Netflix revival of Gilmore Girls, the show on which she played the super-talented chef sidekick to Lauren Graham's character, Lorelai Gilmore. McCarthy may be the best-known graduate of Gilmore Girls, which premiered in 2000 and aired for seven years.
Sadly, we still have half the month of September left. So we have no choice but to indulge in as much Gilmore nostalgia as possible. From Alexis Bledel's actual coffee intake to the creators' original plans for Luke Danes (Scott Patterson), here are 12 facts about Gilmore Girls that might surprise you. 1. A Jess Mariano spinoff almost happened. When Rory's (Bledel) bad boy boyfriend ran away to L.A., everyone was pretty bummed out.