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1 For a medium rare roast: Cook the roast for 20 minutes for every pound. 2  If you were cooking a 5 pound roast, you would cook it for 100 minutes. 3  For a medium roast: Allow 22 minutes of cooking time for every pound.
Photo Credit Diane Shear/Demand Media. Lower heat to 325 F, and continue cooking the pork roast. According to the U.S. Department of Agriculture, you should figure on cooking bone-in pork roasts for 20 to 25 minutes per pound.A 5-pound roast, for example, will need between 100 and 125 minutes of total cooking time, which includes the searing time.hoto Credit Diane Shear/Demand Media. Lower heat to 325 F, and continue cooking the pork roast. According to the U.S. Department of Agriculture, you should figure on cooking bone-in pork roasts for 20 to 25 minutes per pound.