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Approximate Cost of Botox for migraine. The cost of a 100 unit vial of Botox is approximately $525. Note that a typical dose of Botox for migraine treatment is 155 units.
The average cost for a round of BotoxÂ® is about $500, but the specifics will obviously vary a lot from patient to patient. Some patients pay as little as $200 and some pay upwards of $900.