Related Content: Abstract: Efficient tools for profiling DNA methylation in specific genes are essential for epigenetics and clinical diagnostics. Current DNA methylation profiling techniques have been limited by inconvenient implementation, requirements of specific reagents, and ...
Autosomal Trisomy Chromosome Diseases. The 22 non-sex autosome chromosomes (autosomes) can also exhibit disorders, of which the most common is trisomy (having 3 copies rather than a pair). Because these are disorders of the autosomes and not the sex chromosomes, these disorders can occur with males or females.
Down Syndrome is the most well known disease caused by chromosomal abnormalities. In this disorder there is a third copy of chromosome 21 (there are two copies of each chromosome in the cells of healthy humans). Chromosomal diseases can be also caused by segments and joins of parts of chromosomes.