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Approximate Cost of Botox for migraine. The cost of a 100 unit vial of Botox is approximately $525. Note that a typical dose of Botox for migraine treatment is 155 units.
Typically, treatments run $300-$1,200 depending on how much you need and who administers it. Treatments may be every 3 months. A nurse administering Botox in a mall on average costs $9-$12 per unit, or $200-$300 per area (with 20-30 units), which can run $200-$600 for a typical treatment.