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The push-up requires many muscle groups, but the primary muscle groups are the chest muscles, the pectoralis major and minor. These are the two large chest muscles and mainly the pushing muscle group of the upper body. When pushing and lowering the body during a push up, the pectoralis major is doing most of the work.
The pushup chiefly targets the chest, shoulders and triceps, the muscles on the back of the upper arm. In the chest area, pushups work the pectoralis major, the thick, slab-like muscles that span from the collarbone to the upper ribcage. As the shoulders drive the motion of raising and lowering your body, the pushup focuses on the main muscle of this body part, the deltoids.