The TARDBP gene provides instructions for making a protein called transactive response DNA binding protein 43 kDa (TDP-43). This protein is found within the cell nucleus in most tissues and is involved in many of the steps of protein production.
(CNN)Sookie St. James, say it isn't so! Superstar comedian Melissa McCarthy says she wasn't asked to return to the Netflix revival of Gilmore Girls, the show on which she played the super-talented chef sidekick to Lauren Graham's character, Lorelai Gilmore. McCarthy may be the best-known graduate of Gilmore Girls, which premiered in 2000 and aired for seven years.
Lorelai Victoria Gilmore, played by Lauren Graham, is the only daughter of Richard and Emily Gilmore. She is the mother of Lorelai Rory Leigh Gilmore. She became pregnant at the age of 16 but refused to marry Christopher Hayden, Rory's father, because she felt that a marriage at such a young age would not work out.