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Oral thrush is the most common reason to use Diflucan for infants. Back to list. What is the Diflucan Infants Dosage? For oral thrush (oral candidiasis): The dose of Fluconazole is 6 mg/kg/day for the first dose and then 3 mg/kg/day for further doses. The whole course should last at least 7 days and can be given for up to 2 weeks. A 3.5 kg (about 7 1/2 pounds - 8 pounds) baby would need about 20 mg as the first dose (given just once in the day) and for the next 6-13 days would need 10 mg a day (given just once). The Diflucan oral solution comes as 40mg/ml so 20 mg is 0.5 ml and 10 mg is 0.25 ml.
What Happens. Most cases of thrush are mild and clear up with the use of an antifungal mouth rinse or lozenges. Very mild cases of thrush may clear up without medical treatment. It usually takes about 14 days of treatment with an oral antifungal medicine to cure more severe thrush infections. In some cases, thrush may last several weeks even with treatment.