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myalgia myÂ·alÂ·giÂ·a (mÄ«-Äl'jÄ-É, -jÉ) n. Muscular pain or tenderness, especially when diffuse and nonspecific. Also called myodynia.
Editor's Note: Myalgia is the most common adverse effect associated with the use of statins, which renders those who are intolerant of the symptoms unable to avail themselves of the drugs' potential benefits.