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Hemolytic disease of the newborn (HDN) is a disease in which there is hemolysis in a newborn or fetus caused by blood-group incompatibility between mother and child. There are a bunch of related terms: Immune hydrops (Hydrops means accumulation of edema fluid in the fetus during intrauterine growth.
To prevent early HDNB (which occurs during the first 24 h of life), the CPS also recommended administration of vitamin K to expectant mothers who take drugs that impair vitamin K metabolism [3]. Classic HDNB (occurring in the first week of life) is rarely seen when vitamin K is given to newborn infants [11].