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1 Heart failure can also cause swelling in your abdomen. Sometimes it can cause fluid to accumulate in your lungs (pulmonary edema), which can lead to shortness of breath.  Cirrhosis. Fluid may accumulate in your abdominal cavity (ascites) and in your legs as a result of liver damage (cirrhosis).
Trauma, rupture of blood vessels or bleeding disorders could result in the accumulation of blood in the abdominal cavity. Heart disease, in which there is failure of the right side of the heart, can also cause fluid buildup in the abdomen as the heart loses its capacity to pump blood. This results in a buildup of pressure in the abdominal cavity and causes fluid accumulation as a result of portal hypertension. Liver disease, inflammation of the kidneys or a decrease in the blood albumin levels are other conditions that result in abdominal fluid buildup.