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The results of a trial suggest that combining pregabalin (Lyrica), an anti-seizure drug, with duloxetine (Cymbalta), an antidepressant, can safely improve outcomes in fibromyalgia, including not only pain relief, but also physical function and overall quality of life. Until now, these drugs have been proven, individually, to treat fibromyalgia pain.
in january 2009 the fda approved savella to help manage fibromyalgia in adults available by prescription it is the first drug introduced just for this purpose previous drugs approved to manage fibromyalgia include lyrica pregabalin a nerve pain and epilepsy drug and cymbalta duloxetine another snri