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Approximate Cost of Botox for migraine. The cost of a 100 unit vial of Botox is approximately $525. Note that a typical dose of Botox for migraine treatment is 155 units.
BotoxÂ® is approved by FDA and Health Canada for treatment and prevention of chronic migraine. Health Canada approved BotoxÂ® for the treatment of chronic migraines in 2011. More studies exploring BotoxÂ® benefits in migraine and other types of headaches, are ongoing. The average dose is 100-200 units.