A sponsor seeking orphan designation for a drug must submit a request for designation to OOPD with the information required in 21 CFR 316.20 and 316.21. Each designation request must stand on its own merit.afety and effectiveness of a drug must be established through adequate and well-controlled studies. The Orphan Drug Act (ODA) provides for granting special status to a drug or biological product (âdrugâ) to treat a rare disease or condition upon request of a sponsor.
Missouri Valley, Harrison County, IA Foreclosures. Search for foreclosed homes for sale in Missouri Valley, Harrison County, Iowa.
The City of Grain Valley had a population of 13,418 as of July 1, 2015. Grain Valley ranks in the upper quartile for Population Density and Diversity Index when compared to the other cities, towns and Census Designated Places (CDPs) in Missouri.