The TARDBP gene provides instructions for making a protein called transactive response DNA binding protein 43 kDa (TDP-43). This protein is found within the cell nucleus in most tissues and is involved in many of the steps of protein production.
(CNN)Sookie St. James, say it isn't so! Superstar comedian Melissa McCarthy says she wasn't asked to return to the Netflix revival of Gilmore Girls, the show on which she played the super-talented chef sidekick to Lauren Graham's character, Lorelai Gilmore. McCarthy may be the best-known graduate of Gilmore Girls, which premiered in 2000 and aired for seven years.
Gilmore Girls. Gilmore Girls is an American comedy-drama television series created by Amy Sherman-Palladino starring Lauren Graham and Alexis Bledel. Sherman-Palladino, her husband Daniel Palladino, David S. Rosenthal, and Gavin Polone served as the executive producers. The series debuted on October 5, 2000, on The WB and remained a tent-pole to the network until its move to The CW on September 26, 2006.