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Approximate Cost of Botox for migraine. The cost of a 100 unit vial of Botox is approximately $525. Note that a typical dose of Botox for migraine treatment is 155 units.
5 quick things you should know about BOTOXÂ® treatment. 1It prevents headaches and migraines before they even start. BOTOXÂ® prevents on average 8 or 9 headache days and migraine/probable migraine days a month (vs 6 to 7 for placebo) at 24 weeks. 2It's given every 12 weeks.