Lymphoid tissue: T-lymphocytes and the Thymus. The thymus is a primary lymphoid organ found within the superior mediatinum, behind the upper part of the sternum. This organ is active in children, but at the start of puberty, until old age, it starts to atrophy, producing fewer T-cells.
Long Term Effects of Oxycodone on Your Health. 1  Unintentional Overdose. 2  Tolerance and Increased Abuse. 3  Addiction to Oxycodone. 4  Respiratory Problems. 5  Cardiovascular Problems. 6  Long Term Effects in Brain Functioning and Systems. 7  Other Organ Impairments. 8  Withdrawals and Relapse.
Both oxycodone bioavailability and peak plasma oxycodone concentration are significantly altered by consumption of a high-fat meal. In other words, your body absorbs more oxycodone and will feel the effects of oxycodone longer when you take immediate release oxycodone with high fat. Finally, special populations need to take care when considering oxycodone for therapeutic use.