Related Content: Abstract: Efficient tools for profiling DNA methylation in specific genes are essential for epigenetics and clinical diagnostics. Current DNA methylation profiling techniques have been limited by inconvenient implementation, requirements of specific reagents, and ...
Autosomal Trisomy Chromosome Diseases. The 22 non-sex autosome chromosomes (autosomes) can also exhibit disorders, of which the most common is trisomy (having 3 copies rather than a pair). Because these are disorders of the autosomes and not the sex chromosomes, these disorders can occur with males or females.
Gene mutations are the alterations of the nucleotide sequence of a gene. Gene mutation may alter the function of proteins in the body. Chromosomal mutations can be either an alteration of chromosome structure or chromosome number. The influence of chromosomal mutations is higher than gene mutations. The main difference between gene mutation and chromosomal mutation is the magnitude of alterations that occur in the genetic material by each type of mutation. Reference: 1.Bailey, Regina.