Communication of information between neurons is accomplished by movement of chemicals across a small gap called the synapse. Chemicals, called neurotransmitters, are released from one neuron at the presynaptic nerve terminal.
Follow Trail 12 until it runs back into trail 1 and familiar sights and then you are only about 200 yards from the great Cumberland Falls. To the best of my guessing ability I would say this loop was about 8.5 miles long which took us about 3 hours and 45 minutes.
Hikers can reach the top of Nevada Fall by continuing 1.3 miles (2.1 km) along the Mist Trail (from Vernal Fall). The John Muir Trail also leads to the top of Nevada Fall (bypassing Vernal Fall). The portion of the John Muir Trail between Clark Point and the top of Nevada Fall is closed in winter.