A sponsor seeking orphan designation for a drug must submit a request for designation to OOPD with the information required in 21 CFR 316.20 and 316.21. Each designation request must stand on its own merit.afety and effectiveness of a drug must be established through adequate and well-controlled studies. The Orphan Drug Act (ODA) provides for granting special status to a drug or biological product (âdrugâ) to treat a rare disease or condition upon request of a sponsor.
Missouri Valley, Harrison County, IA Foreclosures. Search for foreclosed homes for sale in Missouri Valley, Harrison County, Iowa.
In 1926, Missouri City became the first town in the county to make use of natural gas. The town was incorporated on March 13, 1956, and a mayor and five city councilmen were elected. A council-manager government was adopted in 1974. The city has three fire stations. Its post office was built in 1959.