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The Missouri Compromise of 1820 was important because it played a significant role in the relationship between the North and the South. It resulted in the admission of Missouri to the Union as a slave state.he Missouri Compromise of 1820 admitted Missouri as a slave state,  and Maine as a free state, to keep the balance of slave/non-slave  states equal in Congress.
The Missouri Compromise was an effort by Congress to defuse the sectional and political rivalries triggered by the request of Missouri late in 1819 for admission as a state in which slavery would be permitted. At the time, the United States contained twenty-two states, evenly divided between slave and free.