Lymphoid tissue: T-lymphocytes and the Thymus. The thymus is a primary lymphoid organ found within the superior mediatinum, behind the upper part of the sternum. This organ is active in children, but at the start of puberty, until old age, it starts to atrophy, producing fewer T-cells.
Long Term Effects of Oxycodone on Your Health. 1  Unintentional Overdose. 2  Tolerance and Increased Abuse. 3  Addiction to Oxycodone. 4  Respiratory Problems. 5  Cardiovascular Problems. 6  Long Term Effects in Brain Functioning and Systems. 7  Other Organ Impairments. 8  Withdrawals and Relapse.
Dependence and withdrawal: As with other opioid medications (narcotics), this medication may become habit-forming if taken for long periods of time. Misuse of oxycodone is usually not a problem when it is used appropriately for pain relief. Physical dependence, or tolerance (a need to take regular doses to prevent physical symptoms) has been associated with narcotic analgesics such as oxycodone.