Tweet. : a pathological accumulation of paired helical filaments composed of abnormally formed tau protein that is found chiefly in the cytoplasm of neurons of the brain and especially the cerebral cortex and hippocampus and that occurs typically in Alzheimer's disease.weet. : a pathological accumulation of paired helical filaments composed of abnormally formed tau protein that is found chiefly in the cytoplasm of neurons of the brain and especially the cerebral cortex and hippocampus and that occurs typically in Alzheimer's disease.
Not only trade but also the production of goods increased as a result of new ways of organizing production. Merchants, entrepreneurs, and bankers accumulated and manipulated capital in unprecedented volume. Most historians locate in the 16th century the beginning, or at least the maturing, of Western capitalism.
There, it was the work of Americans that attracted the most attention. By the end of the century, the United States was the world leader in manufacturing, unfolding what became known as the Second Industrial Revolution. The American economy had emerged as the largest and most productive on the globe.fter the 1850s, the Industrial Revolution entered a new phase as Belgium, France, Germany, the United States, and later Japan industrialized rapidly. The French government supported projects to improve transportation.