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If you cook chuck roast long enough, it will be very tender and delicious. Many folks tend to take it out of the oven too soon, resulting in a tough piece of meat. You really need about 1 hour of cooking per pound of chuck roast.lace dutch oven in a preheated 300 degree oven and cook for about 60 minutes per pound of beef. My 2 1/2 pound roast took about 2 3/4 hours to become tender and delicious.
Place the seasoned roast in your roasting pan with the fat side up. It will drip down and improve the flavor of the lean meat. 3. Multiply the weight of the roast by 30 minutes to find your cooking time. For example, a two and a half pound (1.1kg) roast will need 75 minutes or 1.25 hours.A five pound roast (2.3kg) will need 150 minutes or 2.5 hours.1  If you want it to be medium rare, use 25 minutes per pound.or example, a two and a half pound (1.1kg) roast will need 75 minutes or 1.25 hours. A five pound roast (2.3kg) will need 150 minutes or 2.5 hours. 1  If you want it to be medium rare, use 25 minutes per pound.