1 10/14/2015 4:30 pm - 5:30 pm. 2  BRWN 4102. 3  Dissertation Seminar.  4  Design and Development of Non-Linear Optical Microscopy Data Acquisition and Analysis Techniques  by Shane Sullivan (Simpson Group).
DNA polymerase II (also known as DNA Pol II or Pol II) is a prokaryotic DNA-Dependent DNA polymerase encoded by the PolB gene.DNA Polymerase II is an 89.9-kDa protein and is a member of the B family of DNA polymerases.It was originally isolated by Thomas Kornberg in 1970, and characterized over the next few years.NA Pol II is not the most studied polymerase so there are many proposed functions of this enzyme which are all likely functions but are ultimately unconfirmed. These are: repair of DNA damaged by UV irradiation, replication restart in UV-irradiated E. coli, adaptive mutagenesis, and long-term survival.
[1] RNA polymerase II (RNAP II and Pol II) is an enzyme found in eukaryotic cells. It catalyzes the transcription of DNA to synthesize precursors of mRNA and most snRNA and microRNA. [2][3] A 550 kDa complex of 12 subunits, RNAP II is the most studied type of RNA polymerase.ubunits The eukaryotic core RNA polymerase II was first purified using transcription assays. [4] The purified enzyme has typically 10-12 subunits (12 in humans and yeast) and is incapable of specific promoter recognition. [5] Many subunit-subunit interactions are known.