(kÄn'sÉr) 1  A disease characterized by any of various malignant neoplasms composed of abnormal cells that tend to proliferate rapidly and invade surrounding tissue. Without treatment such as chemotherapy or radiation, cancer cells can metastasize to other body sites and cause organ failure and death. 2  A malignant tumor.
Dosage and Administration (2.6, 2.7) 8/2016. Warnings and Precautions (5.10) 8/2016. INDICATIONS AND USAGE Gleevec is a kinase inhibitor indicated for the treatment of: Newly diagnosed adult and pediatric patients with Philadelphia chromosome positive chronic myeloid leukemia (Ph+ CML) in chronic phase (1.1)
GleevecÂ® (imatinib mesylate) in the treatment of GIST: Gleevec is a type of targeted therapy that works by inhibiting a protein called tyrosine kinase. Tyrosine kinase is overproduced in GIST cells and is responsible for helping the cancer cells survive and grow.