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At onset of muscle contraction, myoglobin (Mb) immediately releases its bound O 2 to the mitochondria. Accordingly, intracellular O 2 tension (P mb O 2) markedly declines in order to increase muscle O 2 uptake (m O 2).t onset of muscle contraction, myoglobin (Mb) immediately releases its bound O 2 to the mitochondria. Accordingly, intracellular O 2 tension (P mb O 2) markedly declines in order to increase muscle O 2 uptake (m O 2).
Muscle contraction is powered by the uptake of oxygen into the muscles. Oxygen is taken in through the lungs and carried to the rest of the body through hemoglobin in the blood. Each hemoglobin molecule carries four molecules of oxygen.