Ehlers-Danlos syndrome facts. Ehlers-Danlos syndromes are a group of disorders which share common features including easy bruising, joint hypermobility (loose joints), skin that stretches easily (skin hyperelasticity or laxity), and weakness of tissues.
Definition of metamorphism. : a change in the constitution of rock; specifically : a pronounced change effected by pressure, heat, and water that results in a more compact and more highly crystalline condition.
Polymorphism refers to the occurrence of different crystalline forms of the same drug substance. Polymorphism in this commentary is defined as in the International Conference on Harmonization (ICH) Guideline Q6A (2), to include solvation products and amorphous forms.