At usual clinical doses and dosing schedules of metformin, steady state plasma concentrations of metformin are reached within 24 to 48 hours and are generally <1 Âµg/mL. During controlled clinical trials of metformin, maximum metformin plasma levels did not exceed 5 Âµg/mL, even at maximum doses.
FBI Director Christopher Wray offered a spirited defense of his agency before Congress on Thursday, four days after President Donald Trump said its reputation was in tatters. Wray, who was appointed by Trump to succeed James Comey, appeared before the House Judiciary Committee and was clearly prepared for questions about the tweet. Asked about it, he spoke for two minutes without notes.
Which president appointed FBI Director James Comey? Answer Wiki. James Comey was appointed by to the office of the director of the Federal Bureau of Investigation by President Barack Obama in June of 2013, with rumors speculating that this would happen about a month earlier. He was confirmed by the Senate on July 29, 2013, and assumed the office at 4:32 pm on September 4th, 2013. he will serve a ten year term. Before being the director of the FBI, Comey was the United States Deputy Attorney General under George W. Bush and ran the day-to-day operations for the Department of Justice.