As outlined in Chapter 4, you begin the proposal development process. with an understanding of the need or problem as the basis for conceptual-. izing your proposed program or intervention. Likewise, when you begin. writing the proposal, the needs/problem statement is typically the first. section completed.
An example of this is Down syndrome. Down syndrome is a disease in which the chromosomes failed to separate properly during meiosis leading to three chromosomes of type 21 instead of two. A person with the condition therefore has a total of 47 chromosomes instead of 46. The non-disjunction can take place either in the formation of the egg or the sperm.
Down syndrome is a lifelong condition. But with care and support, children who have Down syndrome can grow up to have healthy, happy, productive lives. Down syndrome is caused by a problem with a baby's chromosomes. Normally, a person has 46 chromosomes.But most people with Down syndrome have 47 chromosomes.ost children with Down syndrome have: 1  Distinctive facial features, such as a flat face, small ears, slanting eyes, and a small mouth. 2  A short neck and short arms and legs. 3  Low muscle tone and loose joints. 4  Muscle tone usually improves by late childhood.