Cristiano Ronaldo is highest-paid player, Lionel Messi second - Forbes. Real Madrid remain the most valuable football team in the world for a fourth consecutive year, according to Forbes. Cristiano Ronaldo was the world's highest-paid footballer -- and highest-paid team athlete -- last year, according to US business magazine Forbes. Real Madrid star Ronaldo was said to have earned a total of $82 million (Â£56.7m), with an annual salary of $53m (Â£36.7m) and $29m (Â£20m) in endorsements.
A chromosome deletion is also possible, where an entire section of a chromosome is deleted. Diseases that can be caused by deletion mutation can include 22q11.2 deletion syndrome, cystic fibrosis, Turner syndrome, and Williams syndrome.
They may cause a frameshift in the reading of the messenger RNA so that the amino acid sequence is incorrect and the protein product is prematurely terminated by encountering a stop codon. Mutations can be caused by defects in DNA replication. DNA repair systems, or they may be the result of environmental mutagens.