As the gene test is not dependent on gluten intake, it can be used when people have already commenced a gluten free diet. If the gene test is positive, then a gluten challenge followed by small bowel biopsy will be required to test for coeliac disease.he gene test on its own cannot diagnose coeliac disease â only 1 in 30 people who have HLA DQ2 or HLA DQ8 will develop coeliac disease. A gluten free diet should only be started after confirmation of coeliac disease by small bowel biopsy.
This is how to interpret what these gliadin antibodies mean: A positive old test (IgG-gliadin antibody) usually means gluten sensitivity. A positive new test (DGP-IgG and DGP-IgA) means celiac disease. A negative old test usually means that gluten is unlikely to be a problem. A negative new test means that celiac disease is unlikely at the time of the test, but it does not rule out gluten sensitivity. As you can see, there is gliadin antibody confusion. The same name is being used for both tests, but they have different interpretations.
A positive ANA test means autoantibodies are present. By itself, a positive ANA test does not indicate the presence of an autoimmune disease or the need for therapy. Some medications cause a positive ANA. Tell your doctor all prescription, over-the-counter, and street drugs you take. ANA testing can produce a positive result without any actual disease process.