1 The clearance half-life of methadone averages 30 hours. Urinary methadone excretion is pH dependent; excretion is decreased with increased urinary pH.  Patients who are taking methadone for therapeutic purposes excrete both parent methadone and metabolite in their urine.
Erie Insurance Ceo balks at grim diagnosis as he continues to lead by example . Sunday, December 24, 2000. By Deborah Mendenhall, Post-Gazette Staff Writer . The first time Steve Milne laughed in the face of death was in the fall of 1998. He was flying back to Erie after a Boston business trip and a deafening blast rocked the commercial jet during takeoff. This can't be good, thought Milne, who travels frequently as president and chief executive officer for Erie Insurance. He had never before heard a sound like that. Steve Milne, CEO of Erie Insurance, is living with Amyotropic Lateral Sclerosis, more commonly known as ALS or Lou Gehrig's disease. (V.W.H. Campbell Jr., Post-Gazette) Moments later, a shaken flight attendant emerged and informed startled passengers that the plane had blown a tire and that it would undertake an emergency landing.
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