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A: NADPH, or nicotinamide adenine dinucleotide phosphate, is essential for photosynthetic organism carbohydrates. This reduced coenzyme is a high energy molecule and a reduced form of NADP+ that plays a key role in driving the Calvin cycle.
Quick Answer. The difference between NADH and NADPH is that NADPH has an extra phosphate group. While NADH is used primarily to power cellular reactions such as aerobic cellular respiration and glycolysis, during which molecules are broken down, NADPH is used to power photosynthesis.