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In neuroanatomy, a gyrus (pl. gyri) is a ridge on the cerebral cortex. It is generally surrounded by one or more sulci (depressions or furrows; sg. sulcus). Gyri and sulci create the folded appearance of the brain in humans and other mammals.
The surface of hemisphere is made up of grey matter containing many layers of nerve cells, the cerebral cortex. 1  A gyrus is a ridge on the cerebral cortex. 2  The depression between the Gyri is termed sulci. 3  Three deep wide sulci, called fissures, divide each hemisphere into four lobes.