Borderline personality disorder (BPD) is a serious mental illness that can be challenging for everyone involved, including the individuals with the illness, as well their friends and family members.
Acute CCK2 receptor blockade inhibits gastrin-evoked but not histamine-induced acid secretion. Studies both in vivo/in situ and in vitro have suggested that while acetylcholine seems capable of activating parietal cells, it does not affect histamine secretion from ECL cells.astric acid secretion is under nervous and hormonal control. Gastrin, the major circulating stimulus of acid secretion, probably does not stimulate the parietal cells directly but acts to mobilize histamine from the ECL cells in the oxyntic mucosa. Histamine stimulates the parietal cells to secrete HCl.
The effect of hemicholinium on behavior and on brain acetylcholine and choline in the rat.Freeman JJ, Choi RL, Jenden DJ. Behavior and whole brain acetylcholine and choline levels were studied in rats following intraventricular administration of hemicholinium-3.There was an 80% decrease in the content of acetylcholine after 2 hours. The depletion was associated with a decreased turnover of acetylcholine and aggressive behavior.The acetylcholine level did not return to control values until 72 hours after injection, when hemicholinium was still detectable as determined by fluorescence assay.reeman JJ, Choi RL, Jenden DJ. Behavior and whole brain acetylcholine and choline levels were studied in rats following intraventricular administration of hemicholinium-3. There was an 80% decrease in the content of acetylcholine after 2 hours.