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Distance from Clayton, MO to Indianapolis, IN. The total distance from Clayton, MO to Indianapolis, IN is 237 miles. This is equivalent to 381 kilometers or 206 nautical miles. Your trip begins in Clayton, Missouri. It ends in Indianapolis, Indiana. Your flight direction from Clayton, MO to Indianapolis, IN is East (70 degrees from North).
The distance from Detroit to Indianapolis is 463 km or 287 miles. A typical flight between Detroit, and Indianapolis would have a flying time of about 29 mins. This assumes an average flight speed for a commercial airliner of 500 mph, which is equivalent to 805 km/hr or 434 knots.