Category: Prescription Drugs. Vitamin D3 is the form of vitamin D called cholecalciferol. Cholecalciferol is the most widely known of the vitamin D series and is a fat soluble vitamin that is stored to some degree in the body.
This dilation of the vein may cause pain, cause the legs to swell, ache, feel tired, heavy or full. Reflux of blood into the leg vein branches near the skin can also cause visible changes to the legs including spider veins, varicose veins, thickening and discoloration of the skin, and ulcers. Any impairment of blood flow back to the heart is referred to as venous reflux or venous insufficiency. Occasionally blockage of leg veins, due to blood clots or scarring, may alter normal blood flow. Reflux of the superficial veins is the most common form of venous disease. In superficial venous insufficiency, the deep veins are usually normal. Blood from the deep veins may escape through refluxing perforator veins into the dilated superficial veins causing increased venous pressure in the superficial veins. Changes in the legs due to venous reflux (varicose veins, spider veins, ulcers, pain, aching, etc) are typically caused by larger refluxing veins below the skin that may not be visible without specialized equipment.
Weakness or damage to veins in your legs. Chronic venous insufficiency, in which the one-way valves in your leg veins are weakened or damaged, allows blood to pool in the leg veins and cause swelling. Abrupt onset of swelling in one leg accompanied by pain in your calf can be due to a clot in one of your leg veins.