Too frequently, they use the term loosely to invoke the concept of innovation in support of whatever it is they wish to do. Many researchers, writers, and consultants use âdisruptive innovationâ to describe any situation in which an industry is shaken up and previously successful incumbents stumble.
Alendronic acid (INN) or alendronate sodium (USAN) â sold as Fosamax by Merck â is a bisphosphonate drug used for osteoporosis and several other bone diseases.It is marketed alone as well as in combination with vitamin D (2,800 IU and 5,600 IU, under the name Fosamax+D).Merck's U.S. patent on alendronate expired in 2008 and the drug is now available as a generic.lendronic acid (INN) or alendronate sodium (USAN) â sold as Fosamax by Merck â is a bisphosphonate drug used for osteoporosis and several other bone diseases.
A report published in the New England Journal of Medicine (NEJM) found that patients who took a three drug regimen using oral generic drugs saw just as much improvement in their symptoms as those who underwent a costlier biologic treatment using Enbrel, an injectable brand name drug sold by Amgen (NASDAQ: AMGN).he 48-week, double-blind study randomly assigned 353 patients with rheumatoid arthritis to a triple regimen of disease-modifying anti-rheumatic drugs or Enbrel (etanercept) plus methotrexate.