This model is based on the in vitro skin model Skin2 [5] which had been discontinued in October 1996. It was further proposed by industry to apply the model in a tiered strategy to identify those chemicals that are predicted to be likely to be phototoxic in the 3T3-NRU-PT but are negative in vivo [6].
401(k) contribution rules. On a pretax basis, employees can't contribute above certain limits. In 2015, for instance, the limit is $18,000; those 50 and older can make additional catch-up contributions of $6,000.This money is not counted toward income, and all gains are tax-deferred. The limits are the same for Roth 401(k)s, though the contributions do count toward income and all gains are tax-free.But employees can sock away a lot more retirement cash if their company plan offers an after-tax option in a traditional 401(k).he limits are the same for Roth 401(k)s, though the contributions do count toward income and all gains are tax-free. But employees can sock away a lot more retirement cash if their company plan offers an after-tax option in a traditional 401(k).
Employer Sponsored 401(k) and 403(b) Plans. 2015 401(k) contribution limits, which also applies to 403b, 457 plans, and the federal governmentâs Thrift Savings Plan, rose by $500 from 2014 standard contribution limits. This is a result of final inflation figures per the latest cost of living adjustment (COLA) figures.or those over 50, SIMPLE IRA or SIMPLE 401(k) plans may permit catch-up contributions up to $2,500. This is above the standard $11,500 contribution limit for SIMPLE IRA plans. You can also make catch-up contributions of up to $1,000 to your Traditional or Roth IRA.