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It is safe to take penicillin while pregnant. Penicillin falls in the pregnancy category B. The medicine has been around for a long time and shows no adverse effect on pregnant women. Doctors usually prescribe penicillin to treat strep throat or a UTI.
Length of treatment depends on how severe the syphilis is, and factors such as the patient's overall health. To treat syphilis during pregnancy, penicillin is the drug of choice. Tetracycline cannot be used for treatment because it is dangerous to the unborn baby.