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Distribution of edema: Unilateral. leg edema is generally due to a local cause such as deep vein thrombosis, venous insufficiency, or lymphedema. Bilateral. edema can be due to a local cause or systemic disease, such as heart failure or kidney disease. Generalized. edema is due to systemic disease.
Non-filarial elephantiasis is non-parasitic and is caused by the exposure to intense form of volcanic ashes. People who walk barefoot on the soil may receive the poisonous chemicals present in the soil which would eventually affect the lymphatic system and cause swelling.