Cytomegalovirus (CMV) is a prevalent pathogen, with 40 to 100 percent of the general population showing prior exposure by serology.1 Up to 20 percent of children in the United States will have contracted CMV before puberty.
The concept of the Sousaphone was created by the American composer and bandmaster John Philip Sousa, putting it in a category with the Wagner tubaâa horn conceptualized by German composer Richard Wagnerâand the Saxophone, one of the numerous inventions of Belgian instrument maker Adolphe Sax.
Invented around 1690, the clarinet is a single-reed woodwind instrument with a cylindrical tube. The clarinet evolved from an earlier instrument called the chalumeau, the first true single reed instrument. Johann Christoph Denner of Nuremburg with the help of his son Jacob improved the chalumeau, creating a new instrument called the clarinet.