uk â /ËhaÉªÉrÉËki/ us â plural hierarchies. âº a system in which the people within a company or organization are organized into levels according to the authority they have: Every organization has a hierarchy, and trying to understand that, and the systems and processes of the organization, is important. corporate/management/organizational/political, etc. hierachy Many kinds of work are more easily and cheaply managed in corporate hierarchies than by individuals doing deals in the market.
The most common cause of acute histamine toxicity is the result of inadequate refrigeration or spoiled fish. This causes an overgrowth of bacteria which converts histidine to high levels of histamine. Individuals who have unusually low levels of the enzyme diamine oxidase may be more susceptible to histamine toxicity.
The actual mechanism of histamine intolerance (HIT) is under investigation but is thought to be related to a build up of histamine. In a healthy individual, histamine is broken down on a regular basis by two enzymes: DAO and HNMT.hat to do if you think histamine may be a problem for you. If you think you may have histamine intolerance, speak to your physician to evaluate other possible âlook-alikeâ conditions such as true allergies, mast cell disorders or underlying digestive disorders.