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Hypertrophic cardiomyopathy (HCM) is a disease in which a portion of the myocardium (heart muscle) is enlarged without any obvious cause, creating functional impairment of the heart. It is the leading cause of sudden death in young athletes.
hypertrophy. increase in volume of a tissue or organ produced entirely by enlargement of existing cells. See also hyperplasia and proliferation. adj., adj hypertroÂ´phic. asymmetrical septal hypertrophy. 1. hypertrophic cardiomyopathy.2. the term is sometimes limited to cases of hypertrophic cardiomyopathy in which the hypertrophy is localized to the interventricular septum. See also hypertrophic obstructive cardiomyopathy. a hypertrophy denotes an increase in the size or number of constituent fibers of a muscle. Any other condition such as inflammation, tumor, and fatty infiltration that increases the size of a muscle is called. pseudohypertrophy. True or physiologic hypertrophy results from excessive activity of muscle.