Can you reverse the progression of coronary heart disease? Yes. Healthy lifestyle changes can halt plaque build-up in the arteries. They can also lower risk of type 2 diabetes and hypertension, and help shed excess weight. Plaque build-up in our arteries usually happens over many years.
The Descendants of Cosimo deâ Medici. Lorenzo was a poet himself, and supported the work of such Renaissance masters as Botticelli, Leonardo da Vinci and Michelangelo (whom the Medicis commissioned to complete their family tombs in Florence).
Another branch of the family, descended from Silvestroâs distant cousin Giovanni di Bicci deâ Medici, would begin the great Medici dynasty. Giovanniâs elder son, Cosimo (1389-1464), rose to political power in 1434 and ruled Florence as an uncrowned monarch for the rest of his life.