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No, not necessarily, but it can cause a minor issue. iPhones use a Lithium-Ion battery for its power, using while it's charging won't necessarily ruin the battery, but if you're using the phone while the battery is in the charging process, it can cause the phone to think it has more power than it actually has.
Please help! Bree 19.12.2012. If you're phone is completely dead and you're plugging it in to charge it, your best option is to charge it in a wall outlet because it chargers it faster. You're phone is not turning back on because it is dead.It needs enough juice to power on.