Tweet. : a pathological accumulation of paired helical filaments composed of abnormally formed tau protein that is found chiefly in the cytoplasm of neurons of the brain and especially the cerebral cortex and hippocampus and that occurs typically in Alzheimer's disease.weet. : a pathological accumulation of paired helical filaments composed of abnormally formed tau protein that is found chiefly in the cytoplasm of neurons of the brain and especially the cerebral cortex and hippocampus and that occurs typically in Alzheimer's disease.
Not only trade but also the production of goods increased as a result of new ways of organizing production. Merchants, entrepreneurs, and bankers accumulated and manipulated capital in unprecedented volume. Most historians locate in the 16th century the beginning, or at least the maturing, of Western capitalism.
Banks and banking. The thriving British economy after 1660 was made possible mainly because of Britain's financial institutions. Trading houses, insurance companies and banks emerged to underpin Britain's overseas trade and empire. The expansion of overseas trade, especially in the Atlantic, relied on credit, and bills of credit (like modern travellers cheques), which were at the heart of the slave trade.