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When the body is making and using ketones we say that the body is in a state of ketosis. Ketosis begins after about 48 hours (2 days) or water fast for women, or about 72 hours (3 days) of water fast for men.hen the body is making and using ketones we say that the body is in a state of ketosis. Ketosis begins after about 48 hours (2 days) or water fast for women, or about 72 hours (3 days) of water fast for men.
If ketosis continues for long periods of time, serious damage to the liver and kidneys can occur, which is why most low-carbohydrate, or ketogenic diets recommend only short-term use, typically 14 days.xcess ketones are then eliminated during urination. Ketosis occurs when the amount of carbohydrate fuel-the fuel that is needed to run the body-drops below a critical level, forcing the body to turn first to protein and then to fat reserves to do the work carbohydrates normally do.