(kÄn'sÉr) 1  A disease characterized by any of various malignant neoplasms composed of abnormal cells that tend to proliferate rapidly and invade surrounding tissue. Without treatment such as chemotherapy or radiation, cancer cells can metastasize to other body sites and cause organ failure and death. 2  A malignant tumor.
Dosage and Administration (2.6, 2.7) 8/2016. Warnings and Precautions (5.10) 8/2016. INDICATIONS AND USAGE Gleevec is a kinase inhibitor indicated for the treatment of: Newly diagnosed adult and pediatric patients with Philadelphia chromosome positive chronic myeloid leukemia (Ph+ CML) in chronic phase (1.1)
Gleevec should be taken with food and a large glass of water to minimize the risk of stomach gastrointestinal irritation. The recommended dosage of Gleevec is 400 mg per day for patients in chronic phase CML and 600 mg per day for patients in accelerated phase or blast crisis.