Can you reverse the progression of coronary heart disease? Yes. Healthy lifestyle changes can halt plaque build-up in the arteries. They can also lower risk of type 2 diabetes and hypertension, and help shed excess weight. Plaque build-up in our arteries usually happens over many years.
The Descendants of Cosimo deâ Medici. Lorenzo was a poet himself, and supported the work of such Renaissance masters as Botticelli, Leonardo da Vinci and Michelangelo (whom the Medicis commissioned to complete their family tombs in Florence).
Titian's equestrian portrait of Charles V, Holy Roman Emperor of 1548 applied the form again to a ruler. The Equestrian statue of Cosimo I de' Medici (1598) by Giambologna in the center of Florence was a life size representation of the Grand-Duke, erected by his son Ferdinand I.