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This indicates that after youâve taken a gabapentin dose, approximately 50% will have been cleared from your system within 5 to 7 hours (on average). Using this information, we can determine that gabapentin will stay in your system for an estimated 1.15 to 1.60 days after your final dose. In other words, you shouldnât expect any of the gabapentin to remain in systemic circulation after 2 days (48 hours) post-ingestion.
Neurontin/Gabapentin for Opiate Withdrawal. If youâve experienced a back injury that left you in excruciating pain, your doctor may have prescribed an opiate, such as Vicodin, oxycodone or hydrocodone to relieve the pain.Itâs not uncommon for people to become addicted to opiates even after the source of the pain is gone.Neurontin â or its generic form, gabapentin â is currently being tested as a treatment for opiate withdrawal conditions.ne of Neurontinâs benefits is its ability to mimic opiate effects in the body. This means a person can stop taking opiates without suffering harsh withdrawal effects. Part of Neurontinâs mimicking ability is due to how it affects substance P chemical releases in the brain.