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Those of us who are deficient and start on a vitamin D supplement usually take five to six weeks to reach the recommended level of vitamin D. If you're in doubt, it's always best to have a chat with your GP who might arrange a blood test. The B vitamins and vitamin C are all water soluble.
How well vitamin D works depends on the amount of other vitamins and minerals that are present in your body. The other vitamins and minerals needed to help vitamin D work well are called cofactors. To get the most benefit from vitamin D, you must have other cofactors in your body. Vitamin D has a number of cofactors; the ones listed below are the most important. Magnesium.