This model is based on the in vitro skin model Skin2 [5] which had been discontinued in October 1996. It was further proposed by industry to apply the model in a tiered strategy to identify those chemicals that are predicted to be likely to be phototoxic in the 3T3-NRU-PT but are negative in vivo [6].
401(k) contribution rules. On a pretax basis, employees can't contribute above certain limits. In 2015, for instance, the limit is $18,000; those 50 and older can make additional catch-up contributions of $6,000.This money is not counted toward income, and all gains are tax-deferred. The limits are the same for Roth 401(k)s, though the contributions do count toward income and all gains are tax-free.But employees can sock away a lot more retirement cash if their company plan offers an after-tax option in a traditional 401(k).he limits are the same for Roth 401(k)s, though the contributions do count toward income and all gains are tax-free. But employees can sock away a lot more retirement cash if their company plan offers an after-tax option in a traditional 401(k).
3. No Roth Feature: A Solo 401(k) Plan can be made in pre-tax or Roth (after-tax) format. Whereas, in the case of a SIMPLE IRA, contributions can only be made in pre-tax format. In addition, a contribution of $18,000 ($24,00, if the plan participant is over the age of 50) can be made to a Solo 401(k) Roth account.hereas, in the case of a SIMPLE IRA, contributions can only be made in pre-tax format. In addition, a contribution of $18,000 ($24,00, if the plan participant is over the age of 50) can be made to a Solo 401(k) Roth account.