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John Wayne Airport-Orange County Airport is located approximately 4,2 kilometers (2,6 miles) west of Irvine and about 6,1 kilometers (3,8 miles) northeast of Costa Mesa.
1 Mesa is 11 mi from Sky Harbor Intl Airport (Phoenix, AZ). 2  Right now, 65 airlines operate out of Sky Harbor Intl Airport. 3  Sky Harbor Intl Airport offers nonstop flights to 101 cities.  Every week, at least 9,184 domestic flights and 665 international flights depart from Sky Harbor Intl Airport.