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This indicates that after youâve taken a gabapentin dose, approximately 50% will have been cleared from your system within 5 to 7 hours (on average). Using this information, we can determine that gabapentin will stay in your system for an estimated 1.15 to 1.60 days after your final dose. In other words, you shouldnât expect any of the gabapentin to remain in systemic circulation after 2 days (48 hours) post-ingestion.
Thread: How long does gabapentin take to kick in? How long does gabapentin take to kick in? 05-08-2011 05:33 Every 15 minutes for the last 55 minutes, I've been taking doses of gabapentin (Neurontin). My total dosage is now up to 2100mg and I don't feel anything. For those who are experienced with this substance: how long does it usually take for this substance to take effect when the doses are staggered in this way? Also, I am on a semi-full stomach (I know absorption is increased with a full stomach).