A new model of liver regeneration. When the Hippo pathway is inactivated, mature liver cells revert back to a stem cell-like state. Picture shows a group of cells transitioning from a mature cell type (green) to a stem cell type (red).White cells are the cells where Hippo is being inactivated.(Credit: Dean Yimlamai/Boston Children's Hospital).his means the cells turn back the clock to become stem-cell like again, thus allowing them to give rise to functional progenitor cells that can regenerate a diseased liver. The liver has been a model of regeneration for decades, and itâs well known that mature liver cells can duplicate in response to injury.
Sclerotherapy is a medical procedure whereby a chemical, the sclerosant, is injected into a vein to entirely obliterate it. The sclerosant damages the innermost lining of the vessel, resulting in a clot that blocks the blood circulation in the vein beyond. Veins carry unoxygenated blood from the peripheral tissues back to the heart. Since the blood pressure in the veins is low, the blood is pumped by forward by contractions of the heart. To prevent back-flow, most veins have valves that only allow blood only to flow in the direction of the heart.
What is cryotherapy and how does it work? Cryotherapy is a pain treatment that uses a method of localized freezing temperatures to deaden an irritated nerve. Cryotherapy is also used as a method of treating localized areas of some cancers (called cryosurgery), such as prostate cancer and to treat abnormal skin cells by dermatologists. In this article we only discuss its use in nerve conditions. In cryotherapy, a probe is inserted into the tissue next to the affected nerve.