At usual clinical doses and dosing schedules of metformin, steady state plasma concentrations of metformin are reached within 24 to 48 hours and are generally <1 Âµg/mL. During controlled clinical trials of metformin, maximum metformin plasma levels did not exceed 5 Âµg/mL, even at maximum doses.
FBI Director Christopher Wray offered a spirited defense of his agency before Congress on Thursday, four days after President Donald Trump said its reputation was in tatters. Wray, who was appointed by Trump to succeed James Comey, appeared before the House Judiciary Committee and was clearly prepared for questions about the tweet. Asked about it, he spoke for two minutes without notes.
Teupen Group has appointed David Kesser as executive vice president of Teupen USA, the companyâs North American sales and service office located in Charlotte, N.C. Kesser has been a member of the Teupen USA team since 2010, most recently as national sales manager. In his new leadership role as executive vice president, Kesser will assume the tasks of Teupen USAâs former president, Scott Reynolds.