Definition. Rickets (in children) and osteomalacia (in adults) are two forms of a metabolic bone disease resulting from vitamin D deficiency. Both cause softening and weakening of bones because of defective or inadequate bone mineralization. Rickets. Copyright Â© Nucleus Medical Media, Inc.
The flow from west to east: Disease. In terms of diseases, the Columbian Exchange was a wildly unequal affair, and the Americas got the worst of it. The flow of disease from the Americas eastward into Eurasia and Africa was either trivial or consisted of a single important infection.
The Columbian Exchange named after Christopher Columbus happened during the 15th to 17th centuries. The explorers, settlers, and natives exchanged technology, animals, plants, and diseases among the Old World countries and the New World.