(kÄn'sÉr) 1  A disease characterized by any of various malignant neoplasms composed of abnormal cells that tend to proliferate rapidly and invade surrounding tissue. Without treatment such as chemotherapy or radiation, cancer cells can metastasize to other body sites and cause organ failure and death. 2  A malignant tumor.
Dosage and Administration (2.6, 2.7) 8/2016. Warnings and Precautions (5.10) 8/2016. INDICATIONS AND USAGE Gleevec is a kinase inhibitor indicated for the treatment of: Newly diagnosed adult and pediatric patients with Philadelphia chromosome positive chronic myeloid leukemia (Ph+ CML) in chronic phase (1.1)
Using Gleevec for Leukemia. Leukemia is a cancer that affects the blood and bone marrow. The bone marrow normally produces blood cells in amounts the body needs. However, in leukemia, the bone marrow produces a large amount of abnormal blood cells that grow out of control and eventually crowd out the normal, healthy blood cells.