A new model of liver regeneration. When the Hippo pathway is inactivated, mature liver cells revert back to a stem cell-like state. Picture shows a group of cells transitioning from a mature cell type (green) to a stem cell type (red).White cells are the cells where Hippo is being inactivated.(Credit: Dean Yimlamai/Boston Children's Hospital).his means the cells turn back the clock to become stem-cell like again, thus allowing them to give rise to functional progenitor cells that can regenerate a diseased liver. The liver has been a model of regeneration for decades, and itâs well known that mature liver cells can duplicate in response to injury.
Sclerotherapy is a medical procedure whereby a chemical, the sclerosant, is injected into a vein to entirely obliterate it. The sclerosant damages the innermost lining of the vessel, resulting in a clot that blocks the blood circulation in the vein beyond. Veins carry unoxygenated blood from the peripheral tissues back to the heart. Since the blood pressure in the veins is low, the blood is pumped by forward by contractions of the heart. To prevent back-flow, most veins have valves that only allow blood only to flow in the direction of the heart.
What is immunotherapy? Immunotherapy refers to any treatment that uses the immune system to fight diseases, including cancer. Unlike chemotherapy, which kills cancer cells, immunotherapy acts on the cells of the immune system, to help them attack the cancer.