Tweet. : a pathological accumulation of paired helical filaments composed of abnormally formed tau protein that is found chiefly in the cytoplasm of neurons of the brain and especially the cerebral cortex and hippocampus and that occurs typically in Alzheimer's disease.weet. : a pathological accumulation of paired helical filaments composed of abnormally formed tau protein that is found chiefly in the cytoplasm of neurons of the brain and especially the cerebral cortex and hippocampus and that occurs typically in Alzheimer's disease.
Not only trade but also the production of goods increased as a result of new ways of organizing production. Merchants, entrepreneurs, and bankers accumulated and manipulated capital in unprecedented volume. Most historians locate in the 16th century the beginning, or at least the maturing, of Western capitalism.
England is a highly industrialized economy with a well established trade infrastructure. Ever since colonization started, trade has been the most prominent factor of Englandâs economy.The legacy has been continued into the New World as well, with strong trading relations with the EU and other western countries.ngland is a highly industrialized economy with a well established trade infrastructure. Ever since colonization started, trade has been the most prominent factor of Englandâs economy.