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A joint effusion is the presence of increased intra-articular fluid. It may affect any joint. Commonly it involves the knee.
1 Gout and pseudo-gout can also cause fluid on the knee. 2  Uric acid crystals can accumulate in the knee through gout, leading to the knee jointâs inflammation and swelling, while there also could be the formation of calcium crystals in the knee through pseudo-gout.he treatment method when your knee has fluid on it depends on how the fluid built up around or in the knee joint. These are some of the methods that may be considered: 1  Rest â The pain experienced in the knee will reduce with adequate rest, especially if fluid on the knee was caused by a traumatic injury.