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This indicates that after youâve taken a gabapentin dose, approximately 50% will have been cleared from your system within 5 to 7 hours (on average). Using this information, we can determine that gabapentin will stay in your system for an estimated 1.15 to 1.60 days after your final dose. In other words, you shouldnât expect any of the gabapentin to remain in systemic circulation after 2 days (48 hours) post-ingestion.
Gabapentin withdrawal occurs when stopping use of the drug after becoming physically dependent on it. It is possible to become physically dependent on gabapentin even when using the medication only as prescribed, particularly if it is used on a long-term basis.