Polypharmacy, very common in the elderly, and the possibility of drug-drug interactions must be considered as a cause of agitation. Medications such as benzodiazepines, beta-blockers, selective serotonin reuptake inhibitors (SSRIs), neuroleptics and diphenhydramine can cause problems.
Sun Damage. Overexposure is one of the main factors in scalp wrinkles (and wrinkles elsewhere, too). UV radiation speeds the breakdown of elastin and collagen, two things that keep skin tight and firm. As these degenerate, skin begins to sag and wrinkle.
Hair loss is usually caused by problems with the natural hair cycle, but it may also be linked to your scalp health. One trigger is scalp ringworm, a fungal infection usually passed on by towels, brushes or sheets, which can cause scaly, bald patches. Your GP will treat it with oral medication and a medicated shampoo.