Any passenger who does not present the required documentation will not be allowed to board the ship and the cruise line will not issue a refund. Following is a brief summary of the most common documentation requirements in effect at the time of this writing.
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PICOT Defined. (P) â Population refers to the sample of subjects you wish to recruit for your study. There may be a fine balance between defining a sample that is most likely to respond to your intervention (e.g. no co-morbidity) and one that can be generalized to patients that are likely to be seen in actual practice.