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Distance from Clayton, MO to Indianapolis, IN. The total distance from Clayton, MO to Indianapolis, IN is 237 miles. This is equivalent to 381 kilometers or 206 nautical miles. Your trip begins in Clayton, Missouri. It ends in Indianapolis, Indiana. Your flight direction from Clayton, MO to Indianapolis, IN is East (70 degrees from North).
Claypool-area historical tornado activity is near Indiana state average. It is 88% greater than the overall U.S. average. On 4/11/1965, a category F4 (max. wind speeds 207-260 mph) tornado 28.8 miles away from the Claypool town center killed 31 people and injured 252 people.