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When it's used as a treatment to increase your HDL cholesterol or correct a vitamin deficiency, niacin is sold in higher doses that are prescribed by your doctor. Prescription-strength niacin includes such drugs as Niacor and Niaspan. Niacin is also available as an over-the-counter supplement.
High doses (50 mg or more) of niacin can cause side effects. The most common side effect is called niacin flush, which is a burning, tingling sensation in the face and chest, and red or flushed skin.Taking an aspirin 30 minutes prior to the niacin may help reduce this symptom.he most common side effect is called niacin flush, which is a burning, tingling sensation in the face and chest, and red or flushed skin. Taking an aspirin 30 minutes prior to the niacin may help reduce this symptom.