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At onset of muscle contraction, myoglobin (Mb) immediately releases its bound O 2 to the mitochondria. Accordingly, intracellular O 2 tension (P mb O 2) markedly declines in order to increase muscle O 2 uptake (m O 2).t onset of muscle contraction, myoglobin (Mb) immediately releases its bound O 2 to the mitochondria. Accordingly, intracellular O 2 tension (P mb O 2) markedly declines in order to increase muscle O 2 uptake (m O 2).
This process is known as the sliding filament model of muscle contraction because the actin filaments slide over the myosin filaments. The muscular system works with the nervous system to produce the contraction. Neurons (nerve cells) form connections to one or more muscle cells. A chemical, acetylcholine, is released when an impulse is sent which allows the myosin-actin bridge to form.