Cytomegalovirus (CMV) is a prevalent pathogen, with 40 to 100 percent of the general population showing prior exposure by serology.1 Up to 20 percent of children in the United States will have contracted CMV before puberty.
The concept of the Sousaphone was created by the American composer and bandmaster John Philip Sousa, putting it in a category with the Wagner tubaâa horn conceptualized by German composer Richard Wagnerâand the Saxophone, one of the numerous inventions of Belgian instrument maker Adolphe Sax.
The invention of the multi-key piccolo is attributed to the flute teacher from Prague, Michael Janusch, who developed the instrument in 1824. This instrument was equivalent to the flute with six keys customary at the time.