Bond funds are subject to interest rate risk, which is the chance bond prices. overall will decline because of rising interest rates, and credit risk, which is the chance a bond issuer will. fail to pay interest and principal in a timely manner or that negative perceptions of the issuerâs ability to.
Lotronex (alosetron) blocks the action of a chemical called serotonin in the intestines. This slows the movement of stools (bowel movements) through the intestines. Lotronex is used to treat severe, chronic irritable bowel syndrome (IBS) in women who have had diarrhea as the main symptom for at least 6 months. Alosetron should be used only by women who have tried other IBS treatments without success. Alosetron not been shown to be effective in men with IBS.
Linzess Generic is linaclotide. Linaclotide works by increasing the secretion of chloride and water in the intestines, which can soften stools and stimulate bowel movements. Linaclotide is used to treat chronic constipation, or chronic irritable bowel syndrome (IBS) in people who have had constipation as the main symptom.