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Distance from Clayton, MO to Indianapolis, IN. The total distance from Clayton, MO to Indianapolis, IN is 237 miles. This is equivalent to 381 kilometers or 206 nautical miles. Your trip begins in Clayton, Missouri. It ends in Indianapolis, Indiana. Your flight direction from Clayton, MO to Indianapolis, IN is East (70 degrees from North).
Clayton Weather Forecast for Monday, August 14. The Clayton, ID forecast for Aug 14 is 71 degrees and Overcast . There is 78 percentage chance of rain and 3 mph winds from the Southeast.