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No, not necessarily, but it can cause a minor issue. iPhones use a Lithium-Ion battery for its power, using while it's charging won't necessarily ruin the battery, but if you're using the phone while the battery is in the charging process, it can cause the phone to think it has more power than it actually has.
1 I can feel my phone get hot when charging from a wall adapter but my phone does not get hot when charging from a computer. 2  Slower charging typically will allow the battery to store more charge than a fast charge. 3  It's easier to stop the charging process at ~80% when you use a computer USB due to the slower charging. I can feel my phone get hot when charging from a wall adapter but my phone does not get hot when charging from a computer. 2  Slower charging typically will allow the battery to store more charge than a fast charge. 3  It's easier to stop the charging process at ~80% when you use a computer USB due to the slower charging.