(kÄn'sÉr) 1  A disease characterized by any of various malignant neoplasms composed of abnormal cells that tend to proliferate rapidly and invade surrounding tissue. Without treatment such as chemotherapy or radiation, cancer cells can metastasize to other body sites and cause organ failure and death. 2  A malignant tumor.
Dosage and Administration (2.6, 2.7) 8/2016. Warnings and Precautions (5.10) 8/2016. INDICATIONS AND USAGE Gleevec is a kinase inhibitor indicated for the treatment of: Newly diagnosed adult and pediatric patients with Philadelphia chromosome positive chronic myeloid leukemia (Ph+ CML) in chronic phase (1.1)
Life Expectancy Improves. CML patients taking Gleevec (imatinib) were followed for up to eight years. In order to be enrolled in the study, patients needed to be incomplete remission after two years of starting the drug, and the study confirmed that they could expect to live as long as people without cancer.