Definition. Rickets (in children) and osteomalacia (in adults) are two forms of a metabolic bone disease resulting from vitamin D deficiency. Both cause softening and weakening of bones because of defective or inadequate bone mineralization. Rickets. Copyright Â© Nucleus Medical Media, Inc.
The flow from west to east: Disease. In terms of diseases, the Columbian Exchange was a wildly unequal affair, and the Americas got the worst of it. The flow of disease from the Americas eastward into Eurasia and Africa was either trivial or consisted of a single important infection.
Long Term Effects and Synthesis Long Term Effects and Synthesis One long term effect of the Columbian Exchange was the creation of the Triangular Trade, which brought new crops to Europe and started the Middle Passage, which would ship Africans across the the Atlantic to America as the Native Americans died out due to influenza, small pox, and shingles.