As the gene test is not dependent on gluten intake, it can be used when people have already commenced a gluten free diet. If the gene test is positive, then a gluten challenge followed by small bowel biopsy will be required to test for coeliac disease.he gene test on its own cannot diagnose coeliac disease â only 1 in 30 people who have HLA DQ2 or HLA DQ8 will develop coeliac disease. A gluten free diet should only be started after confirmation of coeliac disease by small bowel biopsy.
This is how to interpret what these gliadin antibodies mean: A positive old test (IgG-gliadin antibody) usually means gluten sensitivity. A positive new test (DGP-IgG and DGP-IgA) means celiac disease. A negative old test usually means that gluten is unlikely to be a problem. A negative new test means that celiac disease is unlikely at the time of the test, but it does not rule out gluten sensitivity. As you can see, there is gliadin antibody confusion. The same name is being used for both tests, but they have different interpretations.
What It Is. An IgA test measures the blood level of immunoglobulin A, one of the most common antibodies in the body. Antibodies are proteins made by the immune system to fight bacteria, viruses, and toxins.IgA is found in high concentrations in the body's mucous membranes, particularly the respiratory passages and gastrointestinal tract, as well as in saliva and tears.IgA also plays a role in allergic reactions.ntibodies are proteins made by the immune system to fight bacteria, viruses, and toxins. IgA is found in high concentrations in the body's mucous membranes, particularly the respiratory passages and gastrointestinal tract, as well as in saliva and tears. IgA also plays a role in allergic reactions.