RAS/MAPK signaling helps control the growth and division (proliferation) of cells, the process by which cells mature to carry out specific functions (differentiation), cell movement (migration), and the self-destruction of cells (apoptosis). The RAF1 gene belongs to a class of genes known as oncogenes.
Raigad Fort has a historical significance in India and Maharashtra. Also known as capital of Swarajya(Freedom), this fort was the capital of Chhatrapati Shivaji Maharaj, one of the great heros of India. Shivaji Maharaj,Founder and King of the Maratha Empire, fought against various rulers to defend freedom in the 17th Century. He chose rairi fort as his capital and renamed it to Raigad.
During the winters, the vigrahas (deities) from Kedarnath temple are brought to Ukhimath and worshiped there for six months. Lord Shiva is worshiped as Kedarnath, the 'Lord of Kedar Khand', the historical name of the region.The unstable temple is not directly accessible by road and has to be reached by a 14 kilometres (8.7 mi) uphill trek from Gaurikund.Pony and manchan service is available to reach the structure.emple and past significance [edit]. The temple, at an height of 3,583 m (11,755 ft), 223 km from Rishikesh, on the shores of Mandakini river, a tributary of Ganga, is an impressive stone edifice of unknown date. The structure is believed to have been constructed in the 8th century AD, when Adi Shankara visited.