Cristiano Ronaldo is highest-paid player, Lionel Messi second - Forbes. Real Madrid remain the most valuable football team in the world for a fourth consecutive year, according to Forbes. Cristiano Ronaldo was the world's highest-paid footballer -- and highest-paid team athlete -- last year, according to US business magazine Forbes. Real Madrid star Ronaldo was said to have earned a total of $82 million (Â£56.7m), with an annual salary of $53m (Â£36.7m) and $29m (Â£20m) in endorsements.
A chromosome deletion is also possible, where an entire section of a chromosome is deleted. Diseases that can be caused by deletion mutation can include 22q11.2 deletion syndrome, cystic fibrosis, Turner syndrome, and Williams syndrome.
Insertion or deletion of one or more nucleotides during replication can also lead to another type of mutation known as a frameshift mutation. The outcome of a frameshift mutation is complete alteration of the amino acid sequence of a protein. This alteration occurs during translation because ribosomes read the mRNA strand in terms of codons, or groups of three nucleotides. These groups are called the reading frame.