Depot injection. A depot injection is an injection, usually subcutaneous, intradermal, or intramuscular, that deposits a drug in a localized mass, called a depot, from which it is gradually absorbed by surrounding tissue. Such injection allows the active compound to be released in a consistent way over a long period.
The Vanquish TM is a tunable, focused bipolar radiofrequency device which is FDA-approved for deep tissue heating. The deep tissue heating preferentially focuses in on the fat layer, and causes it to shrink by causing most of the fat cells to die off.
The U.S. FDA has accepted for review a supplemental Biologics Licence Application (sBLA) seeking the approval of Keytruda (pembrolizumab) in combination with Alimta (pemetrexed) and Paraplatin (carboplatin) for patients with metastatic or advanced non-squamous non-small cell lung cancer (NSCLC) without mutations in EGFR or ALK genes.