Story at-a-glance 1  +. Canine leptospirosis, or âlepto,â is an infection caused by at least four species (serovars) of Leptospira bacteria. 2  However, there are over 20 different serovars that are potentially infectious to dogs.3  Leptospirosis isnât a new disease â in fact, itâs ancient.tory at-a-glance 1  +. Canine leptospirosis, or âlepto,â is an infection caused by at least four species (serovars) of Leptospira bacteria. 2  However, there are over 20 different serovars that are potentially infectious to dogs.
Philip Morris, a London-based cigarette manufacturer, created a New York subsidiary in 1902 to sell several of its cigarette brands, including Marlboro. By 1924 they were advertising Marlboro as a woman's cigarette based on the slogan Mild As May.
On the average, people smoked about 40 cigarettes a year. The first commercial cigarettes were made in 1865 by Washington Duke on his 300-acre farm in Raleigh, North Carolina. His hand-rolled cigarettes were sold to soldiers at the end of the Civil War.