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It is safe to take penicillin while pregnant. Penicillin falls in the pregnancy category B. The medicine has been around for a long time and shows no adverse effect on pregnant women. Doctors usually prescribe penicillin to treat strep throat or a UTI.
In the treatment of late syphilis by weekly injections, missing a dose of penicillin for a period of 10-14 days does not require restarting the entire course of injections. The exception to this is in the case of pregnant women in whom there is no latitude for missing a dose of penicillin.