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Introduction. BCG, or bacille Calmette-Guerin, is a vaccine for tuberculosis (TB) disease. Many foreign-born persons have been BCG-vaccinated. BCG is used in many countries with a high prevalence of TB to prevent childhood tuberculous meningitis and miliary disease.CG, or bacille Calmette-Guerin, is a vaccine for tuberculosis (TB) disease. Many foreign-born persons have been BCG-vaccinated.
According to the Centers for Disease Control and Prevention (CDC) guidelines, IGRAs (e.g. the T-SPOT.TB test) may be used in place of a TST in most situations and are preferred for BCG vaccinated individuals and for those persons who are unlikely to return for the reading of the test results.Â².