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Pulmonary Surfactant. Surfactant is a complex substance containing phospholipids and a number of apoproteins. Surfactant reduces surface tension throughout the lung, thereby contributing to its general compliance. Pulmonary surfactant is a surface-active lipoprotein complex formed by type II alveolar cells.ottom left: the phospholipid 1-palmitoyl-2-oleoylphosphatidylcholine (POPC). Center right: sodium bis(2-ethylhexyl)sulfosuccinate (AOT) AOT is a rare surfactant-it is soluble and active in both oil and water. Botton right: pentaethylene glycol monodecyl ether (C12EO5), a non-ionic surfactant. Top of Page.
Without normal pulmonary surfactant present, the attractive forces of the water will cause the alveoli to collapse. Pulmonary surfactant is a complex substance in the lungs which reduces the surface tension of water and therefore, prevents the collapse of the alveoli.Surfactant also plays a role in defending the lungs from bacteria and viruses.ithout normal pulmonary surfactant present, the attractive forces of the water will cause the alveoli to collapse. Pulmonary surfactant is a complex substance in the lungs which reduces the surface tension of water and therefore, prevents the collapse of the alveoli.