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Introduction. BCG, or bacille Calmette-Guerin, is a vaccine for tuberculosis (TB) disease. Many foreign-born persons have been BCG-vaccinated. BCG is used in many countries with a high prevalence of TB to prevent childhood tuberculous meningitis and miliary disease.CG, or bacille Calmette-Guerin, is a vaccine for tuberculosis (TB) disease. Many foreign-born persons have been BCG-vaccinated.
Even if you have had BCG vaccine, you can have a TB skin test. 1  People who have had BCG vaccine still can get latent TB infection and active TB disease. 2  BCG vaccine may help protect young children from getting very sick with TB. 3  This protection goes away as people get older.