Definition. Rickets (in children) and osteomalacia (in adults) are two forms of a metabolic bone disease resulting from vitamin D deficiency. Both cause softening and weakening of bones because of defective or inadequate bone mineralization. Rickets. Copyright Â© Nucleus Medical Media, Inc.
The flow from west to east: Disease. In terms of diseases, the Columbian Exchange was a wildly unequal affair, and the Americas got the worst of it. The flow of disease from the Americas eastward into Eurasia and Africa was either trivial or consisted of a single important infection.
The long-term effects of the Columbian exchange included the swap of food, crops, and animals between the New World and Old World, and the start of the transoceanic trade. In order to produce a profit, Portuguese explorers were the first to established sugar cane plantations in Brazil.