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Experts believe bipolar disorder is partly caused by an underlying problem with specific brain circuits and the balance of brain chemicals called neurotransmitters. Three brain chemicals -- noradrenaline (norepinephrine), serotonin, and dopamine -- are involved in both brain and bodily functions.. A. Doctors don't completely understand the causes of bipolar disorder. But they've gained a greater understanding in recent years of the bipolar spectrum, which includes the elated highs of mania to the lows of major depression, along with various mood states between these two extremes.
Bipolar disorder and Manic Depression Disorder are two terms that describe the same condition. It is believed however that Bipolar is a bit more accurate because the condition â¦ is characterized as being mood swings that seem to swing from one extreme to the other, hence Bipolar. Bipolar disorder is a physiological disease, the levels of certain  chemicals in the brain, and the actual brain waves of bipolar  patients are different Bipolar disorder and Manic Depression  Disorder are two terms that describe the same condition.