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Distribution of edema: Unilateral. leg edema is generally due to a local cause such as deep vein thrombosis, venous insufficiency, or lymphedema. Bilateral. edema can be due to a local cause or systemic disease, such as heart failure or kidney disease. Generalized. edema is due to systemic disease.
Focal bone marrow edema isolated to a single bone is a common finding in the ankle. It is often posttraumatic, related to avulsion fracture or contusion, but other causes such as osteoarthrosis, inflammatory arthritides, and impingement can also produce focal bone marrow edema.one marrow edema secondary to bone impaction or bone contusions is likely the result of trabecular microfractures, edema, hemorrhage, or reaction after stress. This pattern is common after ankle inversion injuries and is often noted in the apposing medial malleolus and talus.