Tweet. : a pathological accumulation of paired helical filaments composed of abnormally formed tau protein that is found chiefly in the cytoplasm of neurons of the brain and especially the cerebral cortex and hippocampus and that occurs typically in Alzheimer's disease.weet. : a pathological accumulation of paired helical filaments composed of abnormally formed tau protein that is found chiefly in the cytoplasm of neurons of the brain and especially the cerebral cortex and hippocampus and that occurs typically in Alzheimer's disease.
Not only trade but also the production of goods increased as a result of new ways of organizing production. Merchants, entrepreneurs, and bankers accumulated and manipulated capital in unprecedented volume. Most historians locate in the 16th century the beginning, or at least the maturing, of Western capitalism.
The economic history of the United Kingdom deals with the economic history of the United Kingdom of Great Britain after its formation in 1707.(For earlier periods see Economy of England in the Middle Ages and Economic history of Scotland).y 1900, the United States and Germany had developed large-scale industries; Britain's comparative economic advantage had lessened. London did remain the financial and entrepreneurial capital of the world, until challenged by New York after 1918.