RAS/MAPK signaling helps control the growth and division (proliferation) of cells, the process by which cells mature to carry out specific functions (differentiation), cell movement (migration), and the self-destruction of cells (apoptosis). The RAF1 gene belongs to a class of genes known as oncogenes.
Raigad Fort has a historical significance in India and Maharashtra. Also known as capital of Swarajya(Freedom), this fort was the capital of Chhatrapati Shivaji Maharaj, one of the great heros of India. Shivaji Maharaj,Founder and King of the Maratha Empire, fought against various rulers to defend freedom in the 17th Century. He chose rairi fort as his capital and renamed it to Raigad.
Attacked Mughal contingent & captured the fort but looses his life. Shivaji salutes Tanaji's bravery & names kondhana as Sinhgad(Lion fort). Birth of Rajaram(24-02-1670). Shivaji's second wife Soyarabai gave birth to Rajaram, Shivaji's second son. Kalyan captured by Shivaji maharaj(15-03-1670). 1670 was the year of great action. After Kondhana Shivaji maharaj never looked back & captured all the forts & land he had surrendered to Aurangzeb.