Epidemiologic data on the incidence of different types of pyelonephritis are limited. It is known that the incidence of acute pyelonephritis is highest in otherwise healthy women between 15 and 29 years of age, followed by infants and older persons.
The other kind of Diastat syringe contains a small dose that is appropriate for young children (Diastat 2.5 mg) and does not need to be set. The largest Diastat AcuDial syringe (20 mg) comes with a rectal tip that is too large for most children.
In the management of ACS, initiate BRILINTA treatment with a 180 mg loading dose. Administer 90 mg twice daily during the first year after an ACS event. After one year administer 60 mg twice daily. Do not administer BRILINTA with another oral P2Y12 platelet inhibitor. Use BRILINTA with a daily maintenance dose of aspirin of 75-100 mg [see Warnings and Precautions (5.2) and Clinical Studies (14.1)]. A patient who misses a dose of BRILINTA should take one tablet (their next dose) at its scheduled time.