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Introduction. BCG, or bacille Calmette-Guerin, is a vaccine for tuberculosis (TB) disease. Many foreign-born persons have been BCG-vaccinated. BCG is used in many countries with a high prevalence of TB to prevent childhood tuberculous meningitis and miliary disease.CG, or bacille Calmette-Guerin, is a vaccine for tuberculosis (TB) disease. Many foreign-born persons have been BCG-vaccinated.
The BCG vaccine is not generally recommended for use in the United States because of the low risk of infection with tuberculosis bacteria, the variable effectiveness of the vaccine against adult pulmonary tuberculosis, and the vaccine's potential interference with TB skin test reactivity.n the parts of the world where tuberculosis is common, infants may receive a vaccine called BCG (Bacille Calmette Guerin) for prevention of the disease.