If ACTH independent, it is due to the autonomous function of one or both adrenal glands, including adrenal adenomas, adrenocortical carcinomas, and micronodular or macronodular hyperplasia. The clinical manifestations of Cushing's syndrome are protean and reflect the catabolic actions of cortisol on skin, muscle, bone, liver, and fat.
Prior to pregnancy and into much of the third trimester your cervix is long and thick. As labor nears it begins to shorten and thin out. This action is referred to as effacement. Effacement is generally measured in percentages by doctors and midwives.
Understand the risks of obesity during pregnancy â plus steps to promote a healthy pregnancy. Being obese during pregnancy can have a major impact on your health and your baby's health. Find out about the possible complications, recommendations for weight gain and what you can do to promote a healthy pregnancy. Preeclampsia. 2  Women who are obese are at increased risk of developing a pregnancy complication characterized by high blood pressure and signs of damage to another organ system, often the kidneys (preeclampsia). 3  Infection. 4  Women who are obese during pregnancy are at increased risk of urinary tract infections.