1 Spread of the cancer to other parts of the body: Pain caused by cancer itself is more common in people who have metastatic (or advanced) disease, in which the breast cancer spreads to other parts of the body.
Toxicological Effects: 1  Acute toxicity: Atrazine is slightly to moderately toxic to humans and other animals. 2  Chronic toxicity: Some 40% of rats receiving oral doses of 20 mg/kg/day for 6 months died with signs of respiratory distress and paralysis of the limbs.
Long-term Effects of Fentanyl. Some long-term psychosocial effects of Fentanyl abuse may be showing signs of poor judgment in both work and personal situations. Additionally, with sustained fentanyl abuse, you can: Increase your risk for anoxic injury (damage due to significantly decreased oxygen in the body tissues) and multiple organ system damage.