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â¢ As you go through this topic, keep in mind this flow chart, which outlines the factors affecting blood pressure: Factors Affecting Blood Pressure Peripheral Resistance Vessel Elasticity Blood Volume Cardiac Output Page 2. Goals â¢ To understand the factors that affect peripheral resistance, and therefore blood pressure. â¢ To understand how vessel elasticity, blood volume, and cardiac output affect blood pressure. Page 3. Sources of Peripheral Resistance â¢ One of the main factors that affects blood pressure is peripheral resistance.
High blood pressure can affect your health in four main ways: 1  Hardening of the arteries. 2  Pressure inside your arteries can cause the muscles that line the walls of the arteries to thicken, thus narrowing the passage. 3  A heart attack or stroke can occur if a blood clot blocks blood flow to your heart or brain. Enlarged heart. 2  High blood pressure increases the amount of work for your heart. 3  Like any heavily exercised muscle in your body, your heart grows bigger (enlarges) to handle the extra workload. 4  The bigger your heart is, the more it demands oxygen-rich blood but the less able it is to maintain proper blood flow.