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Here's how to enlarge your veins and arteries for plasma donation: 1  Heat up your arm. When veins become overheated, they expand, and draw closer to the skin. 2  Hold off on drinking and smoking. Both smoking and drinking alcoholic beverages makes veins and arteries smaller and harder. 3  Hold off on the caffeine.
There are three major types of blood vessels: the arteries, which carry the blood away from the heart; the capillaries, which enable the actual exchange of water and chemicals between the blood and the tissues; and the veins, which carry blood from the capillaries back toward the heart.here is a layer of muscle surrounding the arteries and the veins which help contract and expand the vessels. This creates enough pressure for blood to be pumped around the body. Blood vessels are part of the circulatory system, together with the heart and the blood.