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Here's how to enlarge your veins and arteries for plasma donation: 1  Heat up your arm. When veins become overheated, they expand, and draw closer to the skin. 2  Hold off on drinking and smoking. Both smoking and drinking alcoholic beverages makes veins and arteries smaller and harder. 3  Hold off on the caffeine.
Antioxidants, like the ones found in grape seed, help protect blood vessels from damage. Damaged blood vessels can lead to higher blood pressure. In several animal studies, grape seed extract substantially reduced blood pressure.