1 4/2 and 4/8 are also simple quadruple. 2  Notice that a time signature in simple meter will always have a 2, 3, or 4 for the top number. 3  While beats in simple meter are divided into two notes, beats in compound meter are divided into three. 4  To demonstrate this, we will examine 6/8 time.
The Discovery and Isolation of Caffeine. Caffeine has been used as a medicinal and recreational drug since before recorded history, by consumption of caffeine bearing plants. However, the discovery of the chemical did not occur until a young physician called Friedlieb Ferdinand Runge isolated and purified the white crystalline substance in 1819.
Tsui led the research team that first isolated the cystic fibrosis gene in 1989, and the Toronto researchers contributed samples of DNA from people with known CF mutations, as well as control samples known to have no mutations on that gene. Those samples were used to test the value of PNA as a genetic probe.