Background. Dupuytren disease is a fibrosing disorder, which results in slowly progressive thickening and shorting of the palmar fascia leading to debilitating digital contractures, particularly of the metacarpophalangeal (MCP) joints or the proximal interphalangeal (PIP) joints.upuytren contracture is most commonly observed in persons of Northern European descent and affects 4-6% of Caucasians worldwide. Many individuals have bilateral disease (45%); in unilateral cases, the right side is more often affected.
Making the world better, one answer at a time. One difference between epithelial cells and muscle cells is their location in the human body. Epithelial cells are skin cells on the outside of the body.Muscle cells are located in the muscle under the skin.aking the world better, one answer at a time. One difference between epithelial cells and muscle cells is their location in the human body. Epithelial cells are skin cells on the outside of the body.
How is the skin, the largest organ in the body, constructed? The skin has two layers: the upper layer is the epidermis, and the lower layer is the dermis. Below the dermis is the hypodermis, or subcutaneous layer, composed of fat or other connective tissue. The epidermis itself is an epithelium made up of sublayers.The outermost portion consists of many layers of flat, dead, dry epithelial cells called keratinocytes. Clearly this barrier of dead cells needs no blood supply. The waxy surface coating of these cells allows the skin to be waterproof and dry.he epidermis itself is an epithelium made up of sublayers. The outermost portion consists of many layers of flat, dead, dry epithelial cells called keratinocytes. Clearly this barrier of dead cells needs no blood supply. The waxy surface coating of these cells allows the skin to be waterproof and dry.