A cardinal feature of sarcoidosis is the presence of CD4+ T cells that interact with antigen-presenting cells to initiate the formation and maintenance of granulomas (Figure 2 Figure 2 Hypothesized Immunopathogenesis of Sarcoidosis.
Offset may refer to: 1  Offset (film), a 2006 film featuring RÄzvan Vasilescu and Alexandra Maria Lara. 2  Offset (law), a reduction in the amount to be paid by a losing party on the basis of debt owed by the prevailing party. 3  Offset agreement, a trade practice in the aerospace and defense industry.
Offset has a significant effect on many elements of a vehicle's suspension, including suspension geometry, clearance between the tire and suspension elements, the scrub radius of the steering system, and visually, the width of the wheel faces relative to the car's bodywork. Left: Offset 30, right Offset 40.