Larry Kehres is just barely the answer to this question and now has a .925 winning percentage (before 2010 season). If he were to lose two games in 2010, he would slip back behind the coach who held the record for half a century, Milburn Catfish Smith, who had a .924 winning percentage.
Platelets are small blood cells that help stop bleeding after injury to a blood vessel by forming a clot, or plug, in the vessel. Some medications impair platelet function, leading to increased bruising and bleeding. SSRIs decrease an important platelet component called serotonin, which may cause bleeding in some patients. SSRIs include fluoxetine (Prozac), sertraline (Zoloft), paroxetine (Paxil), fluvoxamine (Luvox) and citalopram (Celexa).
Most people take sertraline for at least 6 months. You and your doctor should talk about how long you need to take sertraline. 1  You will not get the full effect for 2-3 weeks. 2  You should take it for at least 6 months after you feel better-otherwise your symptoms can come back. If you have taken more sertraline than it said on the label, you must get help quickly â even if you do not feel any different. 2  Go to A&E. 3  Take your medicine with you, to show to the doctors. 4  Tell them how much you have taken.