Four notable events take place on the mountain each year. The Pikes Peak Ascent and Marathon, a 26-mile round trip foot race up Barr Trail and then back down each August, draws thousands of runners from all over the world. The current Pikes Peak Marathon record, which was set in 1993, is 3 hours 16 minutes 30 seconds. The second event, the Pikes Peak International Hill Climb is a race on the 12.42-mile road, which starts around the 6 1/2 mile mark on the highway. In 2013, Sebastian Loeb set a new record of 8 minutes 13.878 seconds.
In mammals, arachidonic acid is synthesized from linoleic acid. Biochemistry. A polyunsaturated omega-6 fatty acid, which is an essential dietary component for mammals and the precursor for biosynthesis of prostaglandins, thromboxanes and hydroxy-eicosatetraenoic acid derivatives (e.g., leukotrienes). polyunsaturated omega-6 fatty acid, which is an essential dietary component for mammals and the precursor for biosynthesis of prostaglandins, thromboxanes and hydroxy-eicosatetraenoic acid derivatives (e.g., leukotrienes).
Cytochrome P450 enzymes convert arachidonic acid to a variety of hydroperoxy, epoxy, and dihydroxy derivatives including racemic mixtures of 12(S)-HpETE and 12(R)-HpETE or 12(S)-HETE and 12(R)-HETE; the R stereoisomer predominates in these mixtures.n humans, Arachidonate 12-lipoxygenase (12-LO, 12-LOX, ALO12, or platelet type 12-lipoxygenase) is encoded by the ALOX12 gene and expressed primarily in platelets and skin.