1 4/2 and 4/8 are also simple quadruple. 2  Notice that a time signature in simple meter will always have a 2, 3, or 4 for the top number. 3  While beats in simple meter are divided into two notes, beats in compound meter are divided into three. 4  To demonstrate this, we will examine 6/8 time.
The Discovery and Isolation of Caffeine. Caffeine has been used as a medicinal and recreational drug since before recorded history, by consumption of caffeine bearing plants. However, the discovery of the chemical did not occur until a young physician called Friedlieb Ferdinand Runge isolated and purified the white crystalline substance in 1819.
However, this research study also reported that caffeine attains its maximum concentration in the blood 45 minutes after consumption. In previous studies, it was reported that people experienced increased alertness 30 to 45 minutes after consuming beverages containing caffeine.