Standardized uptake value. The standardized uptake value (SUV) is a nuclear medicine term, used in positron emission tomography (PET) as well as in modern calibrated Single Photon Emission Tomography (SPECT) imaging for a (semi)quantitative analysis. Its use is particularly common in the analysis of F]fluorodeoxyglucose (F]FDG) images of cancer patients.
1). tumor-specific antigen. tumor-specific antigen (TSA) any cell-surface antigen of a tumor that does not occur on normal cells of the same origin. V antigen (Vi antigen) an antigen contained in the sheath of a bacterium, as Salmonella typhosa (the typhoid bacillus), and thought to contribute to its virulence.. any of several antigens, coded for by the viral genome, associated with transformation of infected cells by certain DNA tumor viruses. Called also tumor antigen. 2. an antigen present on human erythrocytes that is exposed by treatment with neuraminidase or contact with certain bacteria.
Many of these antigens consist of peptides that are presented to T cells by HLA molecules; they represent potential targets for cancer immunotherapy. Melan-A (also designated MART-1) is a melanocyte differentiation antigen that is specific to melanomas, melanocyte cell lines and retina.Melan-A peptide is recognized by most HLA-A2-restricted tumor-specific tumor-infiltrating lymphocytes in patients with melanoma.Antimelanoma cytotoxic T lymphocytes can be generated with a Melan-A peptide, implicating Melan-A as a potential candidate for antigen-specific immunotherapy in melanoma patients.any of these antigens consist of peptides that are presented to T cells by HLA molecules; they represent potential targets for cancer immunotherapy. Melan-A (also designated MART-1) is a melanocyte differentiation antigen that is specific to melanomas, melanocyte cell lines and retina.