Cotangent Function. The cosecant function given by. and its period, phase shift, asymptotes domain and range are explored interactively. An applet is used, where parameters a, b, c and d are changed to investigate their effects on the graph of f.
Muscles can also become weak and joint stiffness can occur. Because of the generalized, systemic nature of CREST syndrome, it can also affect almost any organ in the body, such as the heart, lungs, and kidneys. Symptoms can include chest pain and hematuria.
Autosomal dominant polycystic kidney disease (ADPKD) is a multisystemic and progressive disorder characterized by cyst formation and enlargement in the kidney (see the image below) and other organs (eg, liver, pancreas, spleen).Up to 50% of patients with ADPKD require renal replacement therapy by 60 years of age.utosomal dominant polycystic kidney disease (ADPKD) is one of the most common inherited disorders in humans. It is the most frequent genetic cause of renal failure in adults, accounting for 6-8% of patients on dialysis in the United States.