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The pancreas detects this rise in blood glucose and starts to secrete insulin. Insulin works by improving the uptake of glucose from the blood across cell membranes and into the cells of the body, and so takes glucose out of the bloodstream.
A counterregulatory hormone that works against the action of insulin. Most people with diabetes know that insulin is secreted by the beta cells of the pancreas. What many donât know is that other cells in the pancreas called alpha cells secrete the hormone glucagon. Glucagon is one of the counterregulatory hormones that helps the body regulate blood glucose levels. In people who donât have diabetes, when blood glucose levels fall, the beta cells secrete less insulin. In addition, the alpha cells secrete more glucagon.