1 Spread of the cancer to other parts of the body: Pain caused by cancer itself is more common in people who have metastatic (or advanced) disease, in which the breast cancer spreads to other parts of the body.
Toxicological Effects: 1  Acute toxicity: Atrazine is slightly to moderately toxic to humans and other animals. 2  Chronic toxicity: Some 40% of rats receiving oral doses of 20 mg/kg/day for 6 months died with signs of respiratory distress and paralysis of the limbs.
Kratom effects. While acting as a stimulant at low doses, at higher doses Kratom has more of a sedative opiate-like effect. What gives it these properties are the alkaloids it contains, more specifically two, mitragynine and 7-hydroxymitragynine. Mitragynine is an opioid agonist, as are the ârealâ opiates such as heroin.