1 Spread of the cancer to other parts of the body: Pain caused by cancer itself is more common in people who have metastatic (or advanced) disease, in which the breast cancer spreads to other parts of the body.
Toxicological Effects: 1  Acute toxicity: Atrazine is slightly to moderately toxic to humans and other animals. 2  Chronic toxicity: Some 40% of rats receiving oral doses of 20 mg/kg/day for 6 months died with signs of respiratory distress and paralysis of the limbs.
The mechanism of action of amantadine in the treatment of Parkinsonâs disease and drug-induced extrapyramidal reactions is not known. Data from earlier animal studies suggest that Symmetrel may have direct and indirect effects on dopamine neurons.