NSAIDs interact with the endocannabinoid system and its endocannabinoids, as COX2 have been shown to utilize endocannabinoids as substrates, and may have a key role in both the therapeutic and adverse effects of NSAIDs, as well as in NSAIDs-induced placebo responses.
Definition: An independent variable is the variable that is changed or controlled in a scientific experiment. Independent variables are the variables that the experimenter changes to test their dependent variable.
The scientific definition of scientific inquiry is the ongoing  process of discovery in science. It is the diverse way in which  scientists study the natural world and its pâ¦rocesses to come up  with facts to back up their theories.