That's a little more than the typical 125 milligrams found in a cup of coffee. About 13 percent of the men reported leaky bladder, but only 4.5 percent had a problem considered moderate or severe - which is more than a few drops of urine leakage during the course of a month.
Irritability can be the result of a wide variety of other conditions, diseases or disorders that directly or indirectly affect the functioning of the brain and nervous system. These include intellectual decline, hypoxia and chronic pain. For more details about causes, see causes of irritability.
1 Anxiety causes profound muscle tension all throughout the day, and often this causes a similar drained feeling that makes your body tired.  Mental Tiredness Some of that tiredness is entirely mental, simply because your brain - like a muscle - can also run out of strength. Anxiety can cause a host of rapid, stressful thoughts. When it does, your brain is incredibly active.