Other mutations in the COL4A3 gene severely decrease or prevent the production of alpha3(IV) chains. As a result, there is a serious deficiency of the type IV collagen alpha3-4-5 network in the basement membranes of the kidney, inner ear, and eye.hese networks make up a large portion of basement membranes, which are thin sheet-like structures that separate and support cells in many tissues. Type IV collagen alpha3-4-5 networks play an especially important role in the basement membranes of the kidney, inner ear, and eye.
Net Financial Debt. View Financial Glossary Index. Financial debt of a company after its ending cash balance has been subtracted. If a company has 50 million in financial debt, but 30 million in cash, the net financial debt is 20 million in financial debt.
For example, if a company possesses $4 million in total assets and $600,000 in total liabilities, the company would have a debt ratio of 15%.This number signifies a great deal of information; the debt ratio is a fundamental calculation used to observe a companyâs riskiness or long-term positioning.or example, if a company possesses $4 million in total assets and $600,000 in total liabilities, the company would have a debt ratio of 15%.