(sabkÉnËtrÓktÉ) , ((American) sabËkontraktÉr) noun. a person who undertakes work for a contractor and is therefore not directly employed by the person who wants such work done. The building contractor has employed several subcontractors to build the block of flats.
Furthermore, three unrelated fragile X patients were found with a C-to-T point mutation at the 14th nucleotide in intron 10 with normal length CGGÂ·CCG repeats (Fig. 1F) (42). Clearly, these point mutations are sufficient for the development of the fragile X syndrome.
There are two main forms of mutations associated with prion disease: point changes (i.e. single nucleotide substitutions or transversions) which cause an amino acid change (missense mutation) or less commonly cause the coding to prematurely terminate (stop or nonsense mutation).here are two main forms of mutations associated with prion disease: point changes (i.e. single nucleotide substitutions or transversions) which cause an amino acid change (missense mutation) or less commonly cause the coding to prematurely terminate (stop or nonsense mutation).