1 Regular eye exams are the only way to catch silent diseases in their early stages, when they're more easily treated. 2  One-size-fits-all reading glasses do not work well for people who have a different prescription in each eye, or whose eyes are not centered in the lens. 3  Headaches are a common problem in those cases.
People who take a blood thinner medicine (anticoagulant) like ELIQUIS, and have medicine injected into their spinal and epidural area, or have a spinal puncture have a risk of forming a blood clot that can cause long-term or permanent loss of the ability to move (paralysis).
CYP3A4 and P-gp inhibitors: When ELIQUIS is coadministered with drugs that are strong dual. inhibitors of cytochrome P450 3A4 (CYP3A4) and P-glycoprotein (P-gp) (e.g., ketoconazole, itraconazole, ritonavir, clarithromycin), the recommended dose is 2.5 mg twice daily [see. Clinical Pharmacology (12.3)].