Medicines that normally reach your bloodstream in very small to moderate amounts are more likely to have significant interactions with grapefruit. This is because the effect of grapefruit can cause much larger amounts of the medicine to get into your bloodstream and cause side effects.
Safety of weight-loss drugs. Drugs for short-term use. Diethylpropion (Tenuate), phentermine (Adipex-P), benzphetamine (Didrex) and phendimetrazine are approved for only short-term use â generally less than 12 weeks. These drugs are classified as controlled substances because they have the potential to be abused.
Alternate weight descriptors such as ideal body weight, adjusted body weight, fat-free weight, and lean body weight are used to prevent drug overexposure with weight-based dosing, but their benefits and limitations must be understood.