(sabkÉnËtrÓktÉ) , ((American) sabËkontraktÉr) noun. a person who undertakes work for a contractor and is therefore not directly employed by the person who wants such work done. The building contractor has employed several subcontractors to build the block of flats.
Furthermore, three unrelated fragile X patients were found with a C-to-T point mutation at the 14th nucleotide in intron 10 with normal length CGGÂ·CCG repeats (Fig. 1F) (42). Clearly, these point mutations are sufficient for the development of the fragile X syndrome.
Fragile X syndrome is caused because people with the disease donât make a particular protein, FMRP. Sometimes someone asks why we canât just feed a person with Fragile X more protein. The problem is not lack of protein; a bunch of proteins wonât help someone who is missing FMRP. It is a specific protein that is missing, not proteins in general.