1 4/2 and 4/8 are also simple quadruple. 2  Notice that a time signature in simple meter will always have a 2, 3, or 4 for the top number. 3  While beats in simple meter are divided into two notes, beats in compound meter are divided into three. 4  To demonstrate this, we will examine 6/8 time.
The Discovery and Isolation of Caffeine. Caffeine has been used as a medicinal and recreational drug since before recorded history, by consumption of caffeine bearing plants. However, the discovery of the chemical did not occur until a young physician called Friedlieb Ferdinand Runge isolated and purified the white crystalline substance in 1819.
Lactic acid was first isolated in 1780 in Sweden by a chemist, Carl Wilhelm Scheele. Carl Wilhelm Scheele first isolated the lactic acid from sour milk as an impure brown syru â¦ p.