You and your healthcare provider should talk regularly (for example, every 3 to 6 months) about the dose you are taking and whether you still need treatment with Estrace Vaginal Cream. Long-term, continuous administration of estrogen, with and without progestin, in women with and without a uterus, has shown an increased risk of endometrial cancer, breast cancer, and ovarian cancer.
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Despite more sales of pickups and SUVs, gas mileage of new vehicles climbed last month for the first time since August, the University of Michigan Transportation Research Institute reports. The average gas mileage of all cars and trucks sold in the U.S. in January was 25.4 miles per gallon. While that was up from 25.1 mpg in December, it was down from August's all-time high of 25.8 mpg. As gas prices have slid, more people have been buying larger, more fuel-thirsty vehicles.