Other mutations in the COL4A3 gene severely decrease or prevent the production of alpha3(IV) chains. As a result, there is a serious deficiency of the type IV collagen alpha3-4-5 network in the basement membranes of the kidney, inner ear, and eye.hese networks make up a large portion of basement membranes, which are thin sheet-like structures that separate and support cells in many tissues. Type IV collagen alpha3-4-5 networks play an especially important role in the basement membranes of the kidney, inner ear, and eye.
Net Financial Debt. View Financial Glossary Index. Financial debt of a company after its ending cash balance has been subtracted. If a company has 50 million in financial debt, but 30 million in cash, the net financial debt is 20 million in financial debt.
What Is Sovereign Debt? Definition: Sovereign debt is how much a country's government owes. It means the same thing as national debt, country debt or government debt because the word sovereign also means national government. It often refers to how much the country owes to outside creditors, which is why it is often used interchangeably with public debt. Sovereign debt is an accumulation of a government's annual deficits. Therefore, it shows how much more a government spends than it receives in revenue over time. Governments usually finance their debt through bonds, such as U.S. Treasury notes. These bonds have terms from three months to 30 years.