A cardinal feature of sarcoidosis is the presence of CD4+ T cells that interact with antigen-presenting cells to initiate the formation and maintenance of granulomas (Figure 2 Figure 2 Hypothesized Immunopathogenesis of Sarcoidosis.
Offset may refer to: 1  Offset (film), a 2006 film featuring RÄzvan Vasilescu and Alexandra Maria Lara. 2  Offset (law), a reduction in the amount to be paid by a losing party on the basis of debt owed by the prevailing party. 3  Offset agreement, a trade practice in the aerospace and defense industry.
Motorcycle offset. The distance between a line drawn through the centre of the steering stem/ headstock axis and the centre line of the front fork tubes. Typically the offset inversely affects trail, if offset increases then the trail will decrease.ake, offset, trail etc] regarding the ride of a bike. I suspect that small changes in yoke angle could have a significant affect on the handling of a bike. Reply. Posted. Altering the rake angle will change the stability/agility of your bike.