If ACTH independent, it is due to the autonomous function of one or both adrenal glands, including adrenal adenomas, adrenocortical carcinomas, and micronodular or macronodular hyperplasia. The clinical manifestations of Cushing's syndrome are protean and reflect the catabolic actions of cortisol on skin, muscle, bone, liver, and fat.
The words effacement, being effaced and effacing are terms that you will hear often as you approach your last trimester. These terms are used to describe the process that the cervix prepares itself for delivery and it is measured by percentage.
Your doctor may be monitoring your progress during the last few weeks of pregnancy. She may tell you that you have begun to dilate or efface. Dilation is the opening of the cervix where effacement is the thinning out of the cervix. Both are a good sign that labor may start soon.