1 Spread of the cancer to other parts of the body: Pain caused by cancer itself is more common in people who have metastatic (or advanced) disease, in which the breast cancer spreads to other parts of the body.
Effects on aquatic organisms: Atrazine is slightly toxic to fish and other aquatic life. Atrazine has a low level of bioaccumulation in fish. In whitefish, atrazine accumulates in the brain, gall bladder, liver, and gut [16]. Effects on other organisms: Atrazine is not toxic to bees [16].
Adverse effects. Memantine is, in general, well-tolerated. Common adverse drug reactions (â¥1% of people) include confusion, dizziness, drowsiness, headache, insomnia, agitation, and/or hallucinations. Less common adverse effects include vomiting, anxiety, hypertonia, cystitis, and increased libido. Like many other NMDA antagonists, memantine behaves as a dissociative anesthetic at supratherapeutic doses. Despite isolated reports, recreational use of memantine is rare due to the drug's long duration and limited availability.