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Here's how to enlarge your veins and arteries for plasma donation: 1  Heat up your arm. When veins become overheated, they expand, and draw closer to the skin. 2  Hold off on drinking and smoking. Both smoking and drinking alcoholic beverages makes veins and arteries smaller and harder. 3  Hold off on the caffeine.
Best Answer: Blood vessels become damaged, you bleed (which washes out debris) and it fills the wound, the blood vessels constrict & blood flow slows down. Platelets in the blood stick to collagen fibres that make up the vessel wall and this acts as a plug.From this point on enzymes (proteins called clotting factors) trigger a chain of events takes place to form a clot: Prothrombin converts to thrombin, calcium is required for this.est Answer: Blood vessels become damaged, you bleed (which washes out debris) and it fills the wound, the blood vessels constrict & blood flow slows down. Platelets in the blood stick to collagen fibres that make up the vessel wall and this acts as a plug.