The City of Holy Cross had a population of 393 as of July 1, 2017. Holy Cross ranks in the upper quartile for Population Density and the lower quartile for Diversity Index when compared to the other cities, towns and Census Designated Places (CDPs) in Iowa. See peer rankings below. The primary coordinate point for Holy Cross is located at latitude 42.6007 and longitude -90.9961 in Dubuque County. The formal boundaries for the City of Holy Cross (see map below) encompass a land area of 0.31 sq. miles and a water area of 0 sq. miles. Dubuque County is in the Central time zone (GMT -6). The elevation is 1,207 feet.
The methylenetetrahydrofolate reductase (MTHFR) mutation test is used to detect two relatively common mutations in the MTHFR gene that are associated with elevated levels of homocysteine in the blood.he MTHFR mutation test may sometimes be ordered when a person has elevated homocysteine levels, especially when the person has a personal or family history of premature cardiovascular disease or thrombosis.
The enzyme is coded by the gene with the symbol MTHFR on chromosome 1 location p36.3 in humans. There are DNA sequence variants (genetic polymorphisms) associated with this gene. In 2000 a report brought the number of polymorphisms up to 24.he MTHFR nucleotide at position 677 in the gene has two possibilities: C (cytosine) or T (thymine). C at position 677 (leading to an alanine at amino acid 222) is the normal allele.