The disease begins in the palm and moves towards the fingers, with the metacarpophalangeal (MCP) joints affected before the proximal interphalangeal (PIP) joints. In Dupuytren's contracture, the palmar fascia within the hand becomes abnormally thick, which can cause the fingers to curl and can impair finger function.
dicyclomine is a medication that relieves spasms in involuntary smooth muscles like those that line the gastrointestinal tract several companies produce dicyclomine in capsule syrup tablet and intramuscular injection formulationsicyclomine is a medication that relieves spasms in involuntary smooth muscles like those that line the gastrointestinal tract several companies produce dicyclomine in capsule syrup tablet and intramuscular injection formulations
Methylene diphenyl diisocyanate, most often abbreviated as MDI, is an aromatic diisocyanate. Three isomers are common, varying by the positions of the isocyanate groups around the rings: 2,2'-MDI, 2,4'-MDI, and 4,4'-MDI. The 4,4' isomer is most widely used. This isomer is also known as Pure MDI. MDI reacts with polyols in the manufacture of polyurethane.