1 Spread of the cancer to other parts of the body: Pain caused by cancer itself is more common in people who have metastatic (or advanced) disease, in which the breast cancer spreads to other parts of the body.
Effects on aquatic organisms: Atrazine is slightly toxic to fish and other aquatic life. Atrazine has a low level of bioaccumulation in fish. In whitefish, atrazine accumulates in the brain, gall bladder, liver, and gut [16]. Effects on other organisms: Atrazine is not toxic to bees [16].
Nearly all Arimidex side effects are resultant of its effect on the body in reduction of total circulating Estrogen levels as a result of the inhibition of the aromatase enzyme. The following are all of the major potential Arimidex side effects associated with Estrogen reduction.