If ACTH independent, it is due to the autonomous function of one or both adrenal glands, including adrenal adenomas, adrenocortical carcinomas, and micronodular or macronodular hyperplasia. The clinical manifestations of Cushing's syndrome are protean and reflect the catabolic actions of cortisol on skin, muscle, bone, liver, and fat.
The words effacement, being effaced and effacing are terms that you will hear often as you approach your last trimester. These terms are used to describe the process that the cervix prepares itself for delivery and it is measured by percentage.
When it is 50 percent effaced, it is about two centimeters long. When it is 100 percent effaced, it is paper-thin.. Effacement can happen over days before labor starts. Or, it can happen over hours as labor progresses. With a first labor, it can take quite a while for the cervix to completely efface.