(sabkÉnËtrÓktÉ) , ((American) sabËkontraktÉr) noun. a person who undertakes work for a contractor and is therefore not directly employed by the person who wants such work done. The building contractor has employed several subcontractors to build the block of flats.
Furthermore, three unrelated fragile X patients were found with a C-to-T point mutation at the 14th nucleotide in intron 10 with normal length CGGÂ·CCG repeats (Fig. 1F) (42). Clearly, these point mutations are sufficient for the development of the fragile X syndrome.
Fragile X syndrome carrier status is often diagnosed in these three ways: 1  evaluation for cause of POI. 2  cascade testing when a family member is found to have Fragile X syndrome, FXPOI, or FXTAS. 3  preconception or prenatal carrier testing.