That's a little more than the typical 125 milligrams found in a cup of coffee. About 13 percent of the men reported leaky bladder, but only 4.5 percent had a problem considered moderate or severe - which is more than a few drops of urine leakage during the course of a month.
Irritability can be the result of a wide variety of other conditions, diseases or disorders that directly or indirectly affect the functioning of the brain and nervous system. These include intellectual decline, hypoxia and chronic pain. For more details about causes, see causes of irritability.
Depression and anger go hand in hand and can cause a revolving cycle thatâs hard to break. Lashing out in anger can lead to alienation and feelings of guilt, which can lead to depression. Long-term depression can make it difficult to handle emotions, increasing the likelihood of anger outbursts.