If ACTH independent, it is due to the autonomous function of one or both adrenal glands, including adrenal adenomas, adrenocortical carcinomas, and micronodular or macronodular hyperplasia. The clinical manifestations of Cushing's syndrome are protean and reflect the catabolic actions of cortisol on skin, muscle, bone, liver, and fat.
The words effacement, being effaced and effacing are terms that you will hear often as you approach your last trimester. These terms are used to describe the process that the cervix prepares itself for delivery and it is measured by percentage.
In the last month of pregnancy the cervix will begin to stretch and thin. This is an indication that the lower portion of the uterus is getting prepared for delivery, as a thinner cervix dilates more easily. Your health care provider can check for effacement in the final two months of pregnancy.