1 4/2 and 4/8 are also simple quadruple. 2  Notice that a time signature in simple meter will always have a 2, 3, or 4 for the top number. 3  While beats in simple meter are divided into two notes, beats in compound meter are divided into three. 4  To demonstrate this, we will examine 6/8 time.
The Discovery and Isolation of Caffeine. Caffeine has been used as a medicinal and recreational drug since before recorded history, by consumption of caffeine bearing plants. However, the discovery of the chemical did not occur until a young physician called Friedlieb Ferdinand Runge isolated and purified the white crystalline substance in 1819.
The virus was first isolated in 1947 from a rhesus monkey in the Zika Forest of Uganda, Africa and was isolated for the first time from humans in 1968 in Nigeria.he first well documented case of Zika virus was in 1964, beginning with a mild headache and progressing to a maculopapular rash, fever, and back pain. Within 2 days, the rash was fading, and within 3 days, the fever was gone and only the rash remained.