That's a little more than the typical 125 milligrams found in a cup of coffee. About 13 percent of the men reported leaky bladder, but only 4.5 percent had a problem considered moderate or severe - which is more than a few drops of urine leakage during the course of a month.
Irritability can be the result of a wide variety of other conditions, diseases or disorders that directly or indirectly affect the functioning of the brain and nervous system. These include intellectual decline, hypoxia and chronic pain. For more details about causes, see causes of irritability.
Unexpected occurrence of the frustration also increases the likelihood of aggression. Frustration does not always lead to aggression, particularly when we deliberately suppress it because either we know that it is wrong or we fear the social consequences of being aggressive (eg.or such people, frustration is more likely to that lead directly to aggression than for other people with a calmer disposition or greater self-control.