Standardized uptake value. The standardized uptake value (SUV) is a nuclear medicine term, used in positron emission tomography (PET) as well as in modern calibrated Single Photon Emission Tomography (SPECT) imaging for a (semi)quantitative analysis. Its use is particularly common in the analysis of F]fluorodeoxyglucose (F]FDG) images of cancer patients.
1). tumor-specific antigen. tumor-specific antigen (TSA) any cell-surface antigen of a tumor that does not occur on normal cells of the same origin. V antigen (Vi antigen) an antigen contained in the sheath of a bacterium, as Salmonella typhosa (the typhoid bacillus), and thought to contribute to its virulence.. any of several antigens, coded for by the viral genome, associated with transformation of infected cells by certain DNA tumor viruses. Called also tumor antigen. 2. an antigen present on human erythrocytes that is exposed by treatment with neuraminidase or contact with certain bacteria.
Antibodies are proteins produced by the immune system that bind to a target antigen on the cell surface. The immune system normally uses them to fight pathogens. Each antibody is specific to one or a few proteins. Those that bind to tumor antigens treat cancer. Cell surface receptors are common targets for antibody therapies and include CD20, CD274 and CD279.