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Here's how to enlarge your veins and arteries for plasma donation: 1  Heat up your arm. When veins become overheated, they expand, and draw closer to the skin. 2  Hold off on drinking and smoking. Both smoking and drinking alcoholic beverages makes veins and arteries smaller and harder. 3  Hold off on the caffeine.
A blood clot is an organized clump of hardened blood. Normal blood clotting helps stop blood loss, such as when you get a minor cut or scrape. However, a blood clot that forms inside a blood vessel (artery or vein) or in the heart is called a thrombus and is a serious medical condition. Blood clots can form in the superficial veins just below your skin, or they can form in the deeper, large veins (deep vein thrombosis).