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The driving distance between Knoxville, TN and Birmingham, AL is approximately 255 miles. The driving time would be approximately 4 hours 15 minutes if you were to travel non- â¦ stop in good driving conditions.
Answer     Detroit is a city in Michigan. The driving distance between Knoxville, TN and Atlanta, GA is approximately 215 miles. 66 miles. its about 150ish miles and takes approximately 2.5-3 hours. The driving distance from Detroit to the Tennessee state line is about 500 road miles.