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The driving distance between Knoxville, TN and Birmingham, AL is approximately 255 miles. The driving time would be approximately 4 hours 15 minutes if you were to travel non- â¦ stop in good driving conditions.
There are 73.92 miles from Birmingham to Piedmont in northeast direction and 86 miles (138.40 kilometers) by car, following the I-59 route. Birmingham and Piedmont are 1 hour 42 mins far apart, if you drive non-stop. This is the fastest route from Birmingham, AL to Piedmont, AL. The halfway point is Ashville, AL. Birmingham, AL and Piedmont, AL are in the same time zone (Central Daylight Time). Current time in both locations is 1:27 am.