Lack of control of the environment is often pinpointed as a cause of frustration and stress in confined animals. When the animal cannot control things, such as the feeding time or the lighting program, and when it cannot escape from things it finds unpleasant, it often behaves in a manner that indicates frustration.
Cavitation can also cause excessive pump vibration, which could damage pump bearings, wearing rings, and seals. A small number of centrifugal pumps are designed to operate under conditions where cavitation is unavoidable.
It is true that transient increases in creatinine can be caused by dehydration. Patients with one kidney such as transplant recipients or kidney donors seem to be particularly susceptible to the effect of dehydration on creatinine.