Back to TopCauses. Injury or surgery involving the leg, ankle, or foot can cause swelling. Swelling may also occur after pelvic surgery, especially for cancer. Long airplane flights or car rides, as well as standing for long periods of time, often lead to some swelling in the feet and ankles.
Medical Definition of Serotonin. Serotonin: A neurotransmitter that is involved in the transmission of nerve impulses. Serotonin can trigger the release of substances in the blood vessels of the brain that in turn cause the pain of migraine. Serotonin is also key to mood regulation; pain perception; gastrointestinal function, including perception of hunger and satiety; and other physical functions.
Not to be confused with SSRI discontinuation syndrome. Serotonin syndrome (SS) is a group of symptoms that may occur following use of certain serotonergic medications or drugs. The degree of symptoms can range from mild to severe. Symptoms include high body temperature, agitation, increased reflexes, tremor, sweating, dilated pupils, and diarrhea.