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Eczema, or atopic dermatitis, may also be a long-term condition affecting the skin. It occurs because of a hypersensitivity reaction (similar to an allergy), in which the skin reacts to triggers, such as dyes, fabrics, soaps, animals, and other irritants.czema appears on the hands very commonly. This is because soaps, lotions, and contact with certain fabric, animals, and other allergens or irritants that the hands come in contact with can cause a reaction in people with hypersensitive skin.
When the eczema is very active (during a âflare-upâ) you may develop small water blisters on the hands and feet, or the affected areas of your skin may become moist and weepy. In areas that are repeatedly scratched, the skin may thicken up (a process known as lichenification), and become even more itchy.n people with atopic eczema, the function of their skin as a barrier to the outside world does not work well, so that irritant and allergy-inducing substance enter their skin, and may cause dryness and inflammation. Atopic eczema is not catching.