1 Spread of the cancer to other parts of the body: Pain caused by cancer itself is more common in people who have metastatic (or advanced) disease, in which the breast cancer spreads to other parts of the body.
Effects on aquatic organisms: Atrazine is slightly toxic to fish and other aquatic life. Atrazine has a low level of bioaccumulation in fish. In whitefish, atrazine accumulates in the brain, gall bladder, liver, and gut [16]. Effects on other organisms: Atrazine is not toxic to bees [16].
Metabolic side effects including hypokalemia, hypomagnesemia, and an increase in serum uric acid, have been relatively common especially with higher doses. Although less common than with thiazide diuretics, mild hyperlipidemia and hypercholesterolemia have been associated with the use of furosemide.