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â¢ As you go through this topic, keep in mind this flow chart, which outlines the factors affecting blood pressure: Factors Affecting Blood Pressure Peripheral Resistance Vessel Elasticity Blood Volume Cardiac Output Page 2. Goals â¢ To understand the factors that affect peripheral resistance, and therefore blood pressure. â¢ To understand how vessel elasticity, blood volume, and cardiac output affect blood pressure. Page 3. Sources of Peripheral Resistance â¢ One of the main factors that affects blood pressure is peripheral resistance.
About 90% to 95% of all high blood pressure cases are what is called primary, or essential hypertension. That means the real cause of the high blood pressure is not known, but a number of factors contribute. You are at increased risk if you 1  -. Have a family history of high blood pressure. Pressure inside your arteries can cause the muscles that line the walls of the arteries to thicken, thus narrowing the passage. 2  A heart attack or stroke can occur if a blood clot blocks blood flow to your heart or brain. 3  Enlarged heart. 4  High blood pressure increases the amount of work for your heart.