Primary cold agglutinin disease is usually associated with monoclonal cold-reacting autoantibodies. Primary cold agglutinin disease is chronic and occurs after the fifth decade of life, with a peak incidence in the seventh and eighth decades. (See Epidemiology.) Secondary cold agglutinin disease may be associated with either monoclonal or polyclonal cold-reacting autoantibodies.
Microsoft was founded by Paul Allen and Bill Gates on April 4, 1975, to develop and sell BASIC interpreters for Altair 8800. It rose to dominate the personal computer operating system market with MS-DOS in the mid-1980s, followed by Microsoft Windows.
This famous photo, taken in 1978, shows the early Microsoft employees in Albuquerque, before the company moved to Washington in 1979. Top row, left to right: Steve Wood, Bob Wallace and Jim Lane. Middle: Bob O'Rear, Bob Greenburg, Marc McDonald and Gordon Letwin. Bottom: Bill Gates, Andrea Lewis, Marla Wood and Paul Allen. This famous photo, taken in 1978, shows the early Microsoft employees in Albuquerque, before the company moved to Washington in 1979. Top row, left to right: Steve Wood, Bob Wallace and Jim Lane.