Midazolam is ineffective for pain and has no analgesic effect during conscious sedation. The drug is a primary choice for conscious sedation because midazolam causes patients to have no recollection of the medical procedure.
Saffron is a plant. The dried stigmas (thread-like parts of the flower) are used to make saffron spice. It can take 75,000 saffron blossoms to produce a single pound of saffron spice. Saffron is largely cultivated and harvested by hand. Due to the amount of labor involved in harvesting, saffron is considered one of the world's most expensive spices. The stigmas are also used to make medicine. Saffron is used for asthma, cough, whooping cough (pertussis), and to loosen phlegm (as an expectorant).
In India, Tibet, and China, saffron has been used to produce the yellow-red color of robes for Hindu and Buddhist monks. The main dye component, crocin, a flavonoid, has also been found in the less expensive gardenia fruit, which is now being developed as an alternative source for dye purposes in China.n some countries, such as Spain, Iran, and India, people know that saffron is worth its price and make good use of it. To meet the demand, world annual production is about 265 tons per year, which is grown on about 90,000 acres of land (if efficiently cultivated, each acre produces about 6 pounds of saffron a year).