From 1839 to 1859, Presque Isle grew large enough to support a hotel, a school, newspapers, churches, and various stores; moreover the extension of the military road to Presque Isle together with a growing population made it possible for mail to be delivered to the area in 1842.
Hormone, erythropoietin: Erythropoietin is a substance produced by the kidney that leads to the formation of red blood cells in the bone marrow. Abbreviated: EPO.The kidney cells that make EPO are specialized and are sensitive to low oxygen levels in the blood coming into the kidney.hese cells release erythropoietin when the oxygen level is low in the kidney. Erythropoietin stimulates the bone marrow to produce more red blood cells which in turn increases the oxygen-carrying capacity of the blood.
Erythropoiesis = formation of erythrocytes. 1  the body must produce about 2.5 million new RBCs every second. 2  in adults, erythropoiesis occurs mainly in the marrow of the sternum, ribs, vertebral processes, and skull bones. 3  begins with a cell called a hemocytoblast or stem cell (below)  rate is regulated by oxygen levels: