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1. The DNA double helix is held together by two types of bonds, covalent andhydrogen. Covalent bonds occur within each linear strand and strongly bond thebases, sugars, and phosphate groups (both within each component and betweencomponents).Hydrogen bonds occur between the two strands and involve a basefrom one strand with a base from the second in complementary pairing.ovalent bonds occur within each linear strand and strongly bond thebases, sugars, and phosphate groups (both within each component and betweencomponents). Hydrogen bonds occur between the two strands and involve a basefrom one strand with a base from the second in complementary pairing.
1 Adenine, Thymine, and Uracil can form TWO hydrogen bonds. 2  Guanine and Cytosine can form THREE hydrogen bonds. 3  In nucleic acids (DNA and RNA), nitrogenous bases can bind to each other by hydrogen bonding.4  Guanine binds to Cytosine, and Cytosine binds to Guanine. 5  In DNA, Adenine binds to Thymine. In RNA, Adenine binds to Uracil. 2  These hydrogen-bond interactions between nucleotides C-G and A-T or A-U are referred to as base-pairing or complementary base-pairing. 3  Base-pairing holds the double-stranded DNA molecule together. 4  Base-pairing is necessary for DNA synthesis, RNA synthesis, and Protein synthesis to occur.