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Non-Hodgkin Lymphoma and the Environment. Non-Hodgkin's lymphomas are a group of cancers that start in lymphoid tissue, also called lymph or lymphatic tissue. The causes of Non-Hodgkin lymphomas are mostly unknown. Specific viruses, immune deficiency, and specific autoimmune conditions have been implicated in increased risk. However, some environmental issues, including exposures to pesticides and solvents, are also being investigated.
Inflammatory and immunologic causes of swollen lymph nodes include diseases such as rheumatoid arthritis and lupus, as well as sensitivity to some medications. Many cancers can also cause swelling of lymph nodes. These may be cancers that originate from the lymph nodes or blood cells, such as lymphomas and leukemias.