References. 1  Shmerling RH. Approach to the patient with myalgia. http://www.uptodate.com/home. 2  LeBlond RF, et al., eds. The spine, pelvis and extremities. 3  Muscle cramps. Merck Manual Professional Version. 4  Sprains, strains and other soft tissue injuries. American Academy of Orthopaedic Surgeons.
Freebase(0.00 / 0 votes)Rate this definition: Hydronephrosis â literally water inside the kidney â refers to distension and dilation of the renal pelvis and calyces, usually caused by obstruction of the free flow of urine from the kidney. Untreated, it leads to progressive atrophy of the kidney.
Necrosis - renal tubular; ATN; Necrosis - acute tubular. Acute tubular necrosis (ATN) is usually caused by a lack of oxygen to the kidney tissues (ischemia of the kidneys). It may also occur if the kidney cells are damaged by a poison or harmful substance. The internal structures of the kidney, particularly the tissues of the kidney tubule, become damaged or destroyed.