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The main feature of nephrotic syndrome is that the kidneys leak a lot of protein. Normally, urine contains virtually no protein. In nephrotic syndrome the urine contains large amounts of protein. What happens is that filters in the kidneys (the glomeruli) become 'leaky' and protein, instead of remaining in the blood, leaks out into the urine. Protein in the urine is called proteinuria. The other key features of nephrotic syndrome are: A low level of protein in the blood as a result of protein loss in the urine. Although there is a drop in many of the proteins normally found in the bloodstream, the main protein that leaks from the blood into the urine is called albumin.
More than ninety-five percent of kidney disease is caused by immune disorder, while kidney disease can also affect immune system in turn. Thereby, how does kidney disease affect immune system? Direct reasons related to kidney disease: As we know, patientsâ kidney structure is often damaged by their disease, which often cause patients to have protein in their urine. While protein is an important substance to our immunity, because some important immune substances like enzyme, antibody, etc, mainly consist of protein.