âIn normal development, the lips form during the seventh week of pregnancy and then the palate forms by week 12. Our study suggests this gene is required for lip formation early on and then again, later, for palate formation,â Moreno adds. Although the study suggests that FOXE1 abnormalities contribute to cleft lip and cleft palate, the researchers have not yet found the exact mutation in the gene that causes clefting. Instead, they have identified a variation in the genetic code that acts as a marker for the mutation.
Classical Antiquity in Greece was preceded by the Greek Dark Ages (c. 1200 â c. 800 BC), archaeologically characterised by the protogeometric and geometric styles of designs on pottery. Following the Dark Ages was the Archaic Period, beginning around the 8th century BC.
Petrarch, who conceived the idea of a European Dark Age. From Cycle of Famous Men and Women, Andrea di Bartolo di Bargilla, c. 1450. The Dark Ages is a historical periodization traditionally referring to the Middle Ages. It emphasizes the demographic, cultural and economic deterioration that supposedly occurred in Western Europe following the decline of the Roman Empire, and the relative scarcity of written records from the period.