Objective To assess the association of candesartan vs losartan with all-cause mortality in patients with HF. Design, Setting, and Patients An HF registry (the Swedish Heart Failure Registry) of 30 254 unique patients registered from 62 hospitals and 60 outpatient clinics between 2000 and 2009.A total of 5139 patients (mean [SD] age, 74 [11] years; 39% women) were treated with candesartan (n = 2639) or losartan (n = 2500).he HRs for losartan vs candesartan were similar for an LVEF of less than 40% and an LVEF of 40% or more, and similar to the whole population (all were statistically significant in favor of candesartan).
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