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Many medicines can cause acute kidney injury (acute renal failure), such as: Antibiotics. These include aminoglycosides, cephalosporins, amphotericin B, bacitracin, and vancomycin. Some blood pressure medicines. One example is ACE inhibitors, such as lisinopril and ramipril. Another is angiotensin receptor blockers.
If the drug is not taken following your healthcare provider's instructions, or if it is an illegal substance, it can cause injury to the kidneys. Your kidneys could be damaged if you take large amounts of over-the-counter medications, such as aspirin, acetaminophen and ibuprofen.