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The main target organs where parathyroid hormone exerts its effects are the bones and the kidneys. When needed, parathyroid hormone is released by the parathyroid glands into the blood and causes the bones to release calcium and increase levels in the bloodstream.
Parathyroid glands. The parathyroid glands are located on the posterior of the thyroid gland. The parathyroid glands produce parathyroid hormone (PTH) which increases blood calcium concentrations when calcium ion levels fall below normal. One of the parathyroid glands' most important functions is to regulate the body's calcium and phosphorus levels.