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Hand cramps are a result of hand muscles and nerve condition. A  common cause of cramping is dehydration, heat exhaustion, fatigue,  and injury or trauma of nerves. This is â¦also common in people with  diabetes and to any condition that affects the nerves outside the  brain and spinal cord. David BÃ¤ckman.
The median nerve, which runs through the arm and hand, can cause swelling pain and numbness if injured. Damage to the ulnar nerve causes swelling, pain and numbness in the forearm, hand, and ring and little fingers. Hypoparathyroidism is a rare condition that can cause muscle twitches, seizures, cramps, tingling, and more. Dupuytren's contracture is a condition of the hand tissue that causes the fingers to curl. Diabetic neuropathy is a nerve condition of the extremities causing numbness, tingling, and pain. Scleroderma is an uncommon immune disorder that causes collagen to build up in the tissue, making it harden. Tetany is a mineral imbalance causing painful muscle cramps and twitches in the hands, feet, face, and larynx.