DMD is caused by a mutation in the dystrophin gene -- usually a large, out-of-frame deletion. Dystrophin is a structural protein associated with the support scaffolding of plasma membrane in muscle cells. Absent dystrophin causes a weakening of muscles, particularly skeletal and cardiac muscle.
The bottom portion of Pesky's Pole, with the Green Monster in the background and Fenway Park 's right field seats in the foreground. Pesky's Pole in the late innings of Boston's 11-6 win over the Oakland Athletics on September 26, 2009. Pesky's Pole, commonly referred to as The Pesky Pole, is the nickname for the right field foul pole at Fenway Park, home of the Boston Red Sox.
The question Will it play in Peoria? has now become a metaphor for whether something appeals to the American mainstream public. Peoria is the home of Ray LaHood, now serving as Secretary of Transportation in President Obama's cabinet. It is also headquarters for Caterpillar Inc., one of the 30 companies composing the Dow Jones Industrial Average.