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A: According to MedicineNet, a low granulocyte count can be caused by bacterial or viral infections, certain cancers, chemotherapy drugs, radiation treatment or certain autoimmune disorders. A low granulocyte count can also occur in healthy people without any known cause. Granulocytes are immune cells that are filled with toxic granules.
The eosinophil count can decrease with stress, with the use of Î²-blockers or corticosteroids, and sometimes during bacterial or viral infections. The count can increase with allergic disorders, during certain infections (typically parasitic), and as a result of numerous other causes (see Eosinophilia). The circulating half-life of eosinophils is 6 to 12 h, with most eosinophils residing in tissues (eg, the upper respiratory and GI tracts, skin, uterus).