The most common cause of renal artery stenosis is atherosclerosis, the same condition that causes narrowing of the arteries in coronary heart disease and stroke, and the risk factors are the same as well. Cholesterol plaques build up along the walls of the renal artery and gradually cause narrowing.
Oxytocin is a commonly used uterotonic that can cause significant and even fatal hypotension, particularly when given as a bolus. The resulting hypotension can be produced by a decrease in systemic vascular resistance or cardiac output through a decrease in venous return.
Causes of Hypotension. Normal blood pressure is between 100 to 140 mm of Hg for systolic pressure and 60 to 90 mm of Hg for diastolic blood pressure. With advancing age the normal blood pressure, and specifically the systolic pressure, increases but within a certain limit.