DMD is caused by a mutation in the dystrophin gene -- usually a large, out-of-frame deletion. Dystrophin is a structural protein associated with the support scaffolding of plasma membrane in muscle cells. Absent dystrophin causes a weakening of muscles, particularly skeletal and cardiac muscle.
The bottom portion of Pesky's Pole, with the Green Monster in the background and Fenway Park 's right field seats in the foreground. Pesky's Pole in the late innings of Boston's 11-6 win over the Oakland Athletics on September 26, 2009. Pesky's Pole, commonly referred to as The Pesky Pole, is the nickname for the right field foul pole at Fenway Park, home of the Boston Red Sox.
pole. 1. either extremity of any axis, as of the fetal ellipse or a body organ. 2. either one of two points which have opposite physical qualities.poÂ´lar. animal pole. 1. the site of an oocyte to which the nucleus is approximated, and from which the polar bodies pinch off.ccipital pole the posterior end of the occipital lobe of the brain. pelvic pole the end of the fetal ellipse at which the breech of the fetus is situated. temporal pole the prominent anterior end of the temporal lobe of the brain.