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Prevalance of Scleroderma: Estimates for the number of people in the United States with systemic sclerosis range from 40,000 to 165,000. By contrast, a survey that included all scleroderma-related disorders, including Raynaud's phenomenon, suggested a number between 250,000 and 992,500.bout prevalence and incidence statistics: The term 'prevalence' of Scleroderma usually refers to the estimated population of people who are managing Scleroderma at any given time.
Werner syndrome is extremely rare, with a prevalence rate of approximately 1:1,000,000 - 1:10,000,000. Regions that have shown a higher frequency of Werner syndrome include Japan (1:100,000) and Sardinia (1:200,000), although these estimates should be observed with caution due to small sample sizes (5).