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In genetics, a biomarker (identified as genetic marker) is a DNA sequence that causes disease or is associated with susceptibility to disease. They can be used to create genetic maps of whatever organism is being studied.ne example of a commonly used biomarker in medicine is prostate-specific antigen (PSA). This marker can be measured as a proxy of prostate size with rapid changes potentially indicating cancer.
In general, geneticists use random primers in their search for DNA markers, but that process is often long and arbitrary, and it can result in researchers spending a lot of time and money to identify just one DNA marker. A PCR-based DNA marker for detection of mutant and normal alleles of thr Wx-D1 gene of wheat. Identification of a null allele at the Wx-B1 locus in some of Iranian bread wheat genotypes. Identification of a closely linked DNA marker, DXS 178, to further refine the X-linked agammaglobulinemia locus.