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Alka-Seltzer Plus Cold and Cough is a combination medicine that treats cold and flu symptoms. Aspirin relieves pain and reduces fever. Chlorpheniramine is an antihistamine that treats runny nose and watery eyes. Dextromethorphan is a cough suppressant. Phenylephrine is a decongestant that clears your sinuses.
Alka-Seltzer is an effervescent antacid and pain reliever first marketed by the Dr. Miles Medicine Company of Elkhart, Indiana. It was developed by head chemist Maurice Treneer. Alka-Seltzer is marketed for relief of minor aches, pains, inflammation, fever, headache, heartburn, stomachache, indigestion, and hangovers, while neutralizing excess stomach acid. It was launched in 1931. A spin-off of Alka-Seltzer made to relieve colds and flu, Alka-Seltzer Plus, was later introduced.