Dangers and Long-Term Effects of Cocaine Abuse. Risk of overdose, damage to the nose and nasal passages, what are the long term effects of use? Cocaine addicts can develop a chronic runny nose and find that their ability to smell is impaired, and their ability to taste also decreased.
A cerebral vasospasm is the term used to describe when a brain artery or smaller brain blood vessels narrow. A blood vesselâs central lumen becomes narrow in response to the vessel wall contraction. This constriction prohibits blood flow.
The Fas receptor is a death receptor on the surface of cells that leads to programmed cell death (apoptosis). It is one of two apoptosis pathways, the other being the mitochondrial pathway. FasR is located on chromosome 10 in humans and 19 in mice.revious reports have identified as many as eight splice variants, which are translated into seven isoforms of the protein. Apoptosis-inducing Fas receptor is dubbed isoform 1 and is a type 1 transmembrane protein. Many of the other isoforms are rare haplotypes that are usually associated with a state of disease.