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The main target organs where parathyroid hormone exerts its effects are the bones and the kidneys. When needed, parathyroid hormone is released by the parathyroid glands into the blood and causes the bones to release calcium and increase levels in the bloodstream.
The parathyroid glands are four tiny glands located behind the thyroid gland. The parathyroid glands produce a substance (parathyroid hormone) that helps control the amount of calcium in the blood.