In addition to the purchase price of a property in France, and the various expenses, commissions, and taxes that that purchase entails, there is a further series of outlays that will arise out of your purchase.
When an enzyme binds its substrate, it forms an enzyme-substrate complex. This complex lowers the activation energy of the reaction and promotes its rapid progression by providing certain ions or chemical groups that actually form covalent bonds with molecules as a necessary step of the reaction process.
In allosteric inhibition (a), an enzyme having a secondary active site called an allosteric site closes the active site, preventing the formation of the enzyme-substrate complex. In allosteric activation (b) the substrate binds to the allosteric site, allowing the active site to open.