DMD is caused by a mutation in the dystrophin gene -- usually a large, out-of-frame deletion. Dystrophin is a structural protein associated with the support scaffolding of plasma membrane in muscle cells. Absent dystrophin causes a weakening of muscles, particularly skeletal and cardiac muscle.
The bottom portion of Pesky's Pole, with the Green Monster in the background and Fenway Park 's right field seats in the foreground. Pesky's Pole in the late innings of Boston's 11-6 win over the Oakland Athletics on September 26, 2009. Pesky's Pole, commonly referred to as The Pesky Pole, is the nickname for the right field foul pole at Fenway Park, home of the Boston Red Sox.
One issue that can arise around the posterior pole is lesions, which may be caused by infections, degenerative eye disease, or congenital conditions. Areas of abnormal tissue in the posterior pole may limit a patientâs vision, particularly when they are located in the macular region.