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Many diseases and conditions can contribute to elevated liver enzymes. Your doctor determines the specific cause of your elevated liver enzymes by reviewing your medications, your signs and symptoms and, in some cases, other tests and procedures. More common causes of elevated liver enzymes include: Certain prescription medications, including statin drugs used to control cholesterol.
Other possible causes of high ALT and AST levels include Wilson's disease, cirrhosis, inflammation of the gallbladder and pancreatitis, explains Mayo Clinic. Most often, elevated liver enzymes are only slightly elevated and do not indicate a problem with the liver. This condition is normally only temporary.