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Elderberry Side Effects Elderberry side effects include gastrointestinal distress and interactions with other herbs, supplements, and drugs. This article provides some information on the same. Elderberry or Sambucus is a genus of about 30 known species of shrubs or small trees.
Do not confuse elderberry with American Elder, Elderflower, or Dwarf Elder. Elderberry is used for âthe flu â (influenza), H1N1 swine flu, HIV /AIDS, and boosting the immune system. It is also used for sinus pain, back and leg pain (sciatica), nerve pain (neuralgia), and chronic fatigue syndrome (CFS) .Y MOUTH 1  : The flu: one tablespoon (15 mL) 4 times daily of a specific elderberry juice-containing syrup (Sambucol, Natureâs Way) daily for 3-5 days. 2  A dose of 15 mL (1 tablespoon) twice daily for 3 days has been used in children.