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Definition. Protein characteristic of the postsynaptic membrane. In a chemical synapse, the postsynaptic membrane is the membrane that receives a signal (binds neurotransmitter) from the presynaptic cell and responds via depolarisation or hyperpolarisation. The postsynaptic membrane is separated from the presynaptic membrane by the synaptic cleft.
1 The part of the synapse that belongs to the receiving neuron is called the postsynaptic membrane. 2  The space between the two is called the synaptic cleft. 3  It is approximately 20 nm wide (20 x 10 -9 m). 4  Presynaptic terminals contain numerous synaptic vesicles.he transmission of information is accomplished in two ways: 1  Electrically: the neuron is directly adjacent to other neurons. 2  Chemically: there is a space (the synaptic cleft) between the axon terminus and the adjacent neuron.