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The initial symptoms of liver failure are often ones that can be due to any number or conditions. Because of this, liver failure may be initially difficult to diagnose. Early symptoms include: 1  Nausea. 2  Loss of appetite. 3  Fatigue.he initial symptoms of liver failure are often ones that can be due to any number or conditions. Because of this, liver failure may be initially difficult to diagnose. Early symptoms include: 1  Nausea. 2  Loss of appetite. 3  Fatigue.
1 The liver is the body's largest internal organ. 2  Many different disease processes can occur in the liver, including infections such as hepatitis, cirrhosis (scarring), cancers, and damage by medications or toxins.  Symptoms of liver disease can include.