Causes of Granuloma. A granuloma is most often caused by inflammation of a small area of tissue from injury or infection. List of causes of Granuloma. Following is a list of causes or underlying conditions (see also Misdiagnosis of underlying causes of Granuloma) that could possibly cause Granuloma includes: Granuloma annulare - a skin condition.
Bisphosphonates and cancer. Bisphosphonates are drugs that slow down or prevent bone damage. They also lower calcium levels. How cancer can affect the bones. Some cancers can cause bone pain and weakness. These are most often cancers that have started in another part of the body and have spread to the bone (secondary bone cancer).
Rare, but serious side effects include: Kidney problems; Osteonecrosis of the jaw (damage to the jawbone) Unusual types of bone fractures; Kidney problems have been seen in patients taking intravenously administered bisphosphonates for long periods of time. The risk of kidney problems may be increased in patients who are taking other drugs that affect the kidney (e.g. Thalomid, non-steroidal anti-inflammatory drugs also known as NSAIDs) or have other conditions associated with kidney problems such as hypertension or diabetes mellitus.