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Search form. Causes. The cause or causes of lymphoma are largely a mystery. There may be some genetic predisposition, or it may be caused by an environmental trigger such as pollution. There is not, however, sufficient evidence to provide a definitive answer.
Causes of Lymphogranuloma. LGV is spread by direct sexual contact with the genitals, rectum, or mouth. Once in the body, bacteria reproduce in the lymph nodes. It may be most closely associated with anal sex and men who have sex with men. Newborns can contract the disease from infected mothers during birth.