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The main target organs where parathyroid hormone exerts its effects are the bones and the kidneys. When needed, parathyroid hormone is released by the parathyroid glands into the blood and causes the bones to release calcium and increase levels in the bloodstream.
The thyroid gland regulates the bodyâs metabolism, while parathyroid glands regulate calcium levels and have no effect on metabolism. Parathyroid Hormone. Parathyroid hormone (PTH) has a very powerful influence on the cells of your bones by causing them to release their calcium into the bloodstream.