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Many medicines can cause acute kidney injury (acute renal failure), such as: Antibiotics. These include aminoglycosides, cephalosporins, amphotericin B, bacitracin, and vancomycin. Some blood pressure medicines. One example is ACE inhibitors, such as lisinopril and ramipril. Another is angiotensin receptor blockers.
Drugs can cause liver disease in several ways. Some drugs are directly injurious to the liver; others are transformed by the liver into chemicals that can be injurious to the liver directly or indirectly. There are three types of liver toxicity: dose-dependent toxicity, idiosyncratic toxicity, and drug allergy. Drugs that cause dose-dependent toxicity can cause liver disease in most people if enough of the drug is taken. The most important example of dose-dependent toxicity is acetaminophen (Tylenol) overdose.