1 Glyburide can cause low blood sugar (hypoglycemia) in some people. 2  This has been more common in elderly people and in people with adrenal, pituitary, liver, or kidney problems, as well as during fasting before surgery and after prolonged exercise. Glyburide is considered a pregnancy Category B or C medication, depending on the type of glyburide prescribed. 2  This means that the drug may or may not be safe for use during pregnancy. 3  Talk to your healthcare provider before using glyburide during pregnancy (see Glyburide and Pregnancy) .
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