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Definition. Protein characteristic of the postsynaptic membrane. In a chemical synapse, the postsynaptic membrane is the membrane that receives a signal (binds neurotransmitter) from the presynaptic cell and responds via depolarisation or hyperpolarisation. The postsynaptic membrane is separated from the presynaptic membrane by the synaptic cleft.
The necessary precursor enzymes must be present in the neuron. There must be enough of the chemical present to actually have an effect on the postsynaptic neuron. The chemical must be released by the presynaptic neuron, and the postsynaptic neuron must contain receptors that the chemical will bind to.