DMD is caused by a mutation in the dystrophin gene -- usually a large, out-of-frame deletion. Dystrophin is a structural protein associated with the support scaffolding of plasma membrane in muscle cells. Absent dystrophin causes a weakening of muscles, particularly skeletal and cardiac muscle.
The bottom portion of Pesky's Pole, with the Green Monster in the background and Fenway Park 's right field seats in the foreground. Pesky's Pole in the late innings of Boston's 11-6 win over the Oakland Athletics on September 26, 2009. Pesky's Pole, commonly referred to as The Pesky Pole, is the nickname for the right field foul pole at Fenway Park, home of the Boston Red Sox.
Kotzebue, Alaska sits on a 3-mile-long spit at the northwest end of Baldwin Peninsula in Kotzebue Sound and about 30 miles above the Arctic Circle. It may look isolated, but this town is the hub of commerce, culture and outdoor activity for the northwestern Arctic region. Kotzebue is a popular stop for visitors on airline package tours who want to see a bit of the Arctic landscape and visit the Innaigvik Education and Information Center to learn about the people. The northwest Arctic is a haven for wildlife and a heaven for who subsist on it or merely want to observe it.