The most common cause of renal artery stenosis is atherosclerosis, the same condition that causes narrowing of the arteries in coronary heart disease and stroke, and the risk factors are the same as well. Cholesterol plaques build up along the walls of the renal artery and gradually cause narrowing.
Oxytocin is a commonly used uterotonic that can cause significant and even fatal hypotension, particularly when given as a bolus. The resulting hypotension can be produced by a decrease in systemic vascular resistance or cardiac output through a decrease in venous return.
The release of oxytocin is stimulated by the digestion of fat. When your small intestine digests fat, it releases a chemical called CCK. CCK signals the brain to release oxytocin, which causes the smooth muscles of your gut to contract. This helps create the feeling of satiety after eating.