First we must appreciate that genes do not act in isolation. The genome in which a genotype is found can affect the expression of that genotype, and the environment can affect the phenotype.Not all pairs of alleles will have the same phenotype: dominance when AA = Aa in phenotype, A is dominant, a is recessive.irst we must appreciate that genes do not act in isolation. The genome in which a genotype is found can affect the expression of that genotype, and the environment can affect the phenotype.
Mannitol may also be used for purposes not listed in this medication guide. You should not receive mannitol if you have severe kidney disease, lung swelling or congestion, severe dehydration, bleeding in your brain not caused by surgery, or if your kidneys have already shut down and you are unable to urinate.o make sure mannitol is safe for you, tell your doctor if you have: 1  a history of kidney disease; 2  heart disease; or. 3  an electrolyte imbalance (such as low levels of potassium or magnesium in your blood).
Common side effects from medical use include electrolyte problems and dehydration. Other serious side effects may include worsening heart failure and kidney problems. It is unclear if use is safe in pregnancy. Mannitol is in the osmotic diuretic family of medications and works by pulling fluid from the brain and eyes.