Rosamaria Corona, MD, DSc. Dermoscopy is a noninvasive, in vivo technique primarily used for the examination of pigmented skin lesions; however, it can also assist observers in assessing many amelanotic lesions. Dermatoscopy, epiluminescence microscopy, incident light microscopy, and skin-surface microscopy are synonyms.
General Discussion. Marfan syndrome is a genetic disorder that affects connective tissue, which is the material between cells of the body that gives the tissues form and strength. Connective tissue is found all over the body and multiple organ systems may be affected in individuals with Marfan syndrome.arfan syndrome is a genetic disorder that affects connective tissue, which is the material between cells of the body that gives the tissues form and strength.
Connective tissue is made up of proteins. The protein that plays a role in Marfan syndrome is called fibrillin-1. Marfan syndrome is caused by a defect (or mutation) in the gene that tells the body how to make fibrillin-1. This mutation results in an increase in a protein called transforming growth factor beta, or TGF-Î².