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The channel has a large diameter of 0.8x1.1nm, and is non-selective for small ions. However, it has an upper exclusion size limit corresponding to molecular weights of about 600 Dalton of permeants. Because most metabolites have molecular weights lower than 600 Da and have been shown to pass through porin channels, porins are called general diffusion pores.
Ion channel receptors are usually multimeric proteins located in the plasma membrane. Each of these proteins arranges itself so that it forms a passageway or pore extending from one side of the membrane to the other.hen an ion channel is open, ions move into or out of the cell in single-file fashion. Individual ion channels are specific to particular ions, meaning that they usually allow only a single type of ion to pass through them.