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pepsinogen. a zymogen secreted by the chief cells of the gastric glands and converted into pepsin in the presence of gastric acid or of pepsin itself.plasma pepsinogen. high levels are indicative of extensive mucosal damage in the abomasum, as in ostertagiasis in ruminants. proenzyme formed and secreted by the chief cells of the gastric mucosa; the acidity of the gastric juice and pepsin itself remove 42 amino acid residues from pepsinogen to form active pepsin. Synonym(s): propepsin. [ pepsin + G. -gen, producing].
Pepsinâs main function is to break down proteins that are found in protein rich foods such as meat, eggs etc. It breaks them into smaller pieces called polypeptides. Interesting thing about pepsin is that it breaks proteins only at certain points so that the protein is not digested completely to the amino acid level.epsinogen is a pro-form zymogen of pepsin. It is released in the stomach by its chief cells. This zymogen is activated by hydrochloric acid released from parietal cells in the stomach linings.