Each tissue type, such as liver, spleen or kidney, has a particular echogenicity in its normal state. In diseased states, the echogenicity of an organ can be altered, either more echogenic (hyperechoic) or less echogenic (hypoechoic) than usual.
burn up. v. 1. To destroy something or someone by fire or heat: She burned the contract up. He burned up all the photographs. 2. To be completely destroyed by fire or heat: The cabin burned up, leaving only ashes.
Pain that is 'burning' is usually associated with injury to the nerves. Sometimes burning pain down the thigh is caused by something called meralgia paresthetica which refers to compression of one of the big sensory nerves to your legs. I don't know if that can cause pain all down to your ankle or not.