According to Mayo Clinic, Down syndrome causes a distinct facial appearance, intellectual disability, developmental delays, and may be associated with thyroid or heart disease in a person. So calling people with this syndrome 'Mongoloid' is extremely vulgar and disrespectful to ethnic Mongolians. Likewise, how will the population react if Down Syndrome was associated with 'European' looks? If you use this term, you are automatically a xenophobic, in my opinion.
If any difference is noteworthy, it would probably be that an age is usually between two times, e.g. 1290-1450AD, whereas an era is less set - but that isn't a rule, its just a matter of usage. Synonyms would be epoch, or eon. Source(s):
Acute vs Chronic. The difference between acute and chronic when used for diseases is that acute means extremely severe pain, brief and dangerous disease whereas chronic refers to a medical condition that lasts over a long period. Chronic also means something always present and recurring or something habitual.