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Venice and Florence, two of Italy's big three art cities, are joined by a fast and efficient rail service, as well as a fast toll road called the Autostrada. The distance between Venice and Florence is about 258 kilometers, or about 160 miles. See also: Four-Day Tour of Venice, Florence and Pisa. Popular Stops en Route
The geographic midpoint between Florence and Rome is in 72.67 mi (116.95 km) distance between both points in a bearing of 153.39Â°. It is located in Italia, Tuscany, Siena, San Casciano dei Bagni (Italia, Toscana, Siena, San Casciano dei Bagni).