If a person's cell have the antigen, the antibody should NOT be present in that person's serum. If an antibody to a blood group antigen is present in the serum of a person, his or her cells should lack that antigen. The antigens are on the cells and the antibodies are in the serum.
Therapy-related myeloid leukemia (t-MDS/t-AML) is a well-recognized clinical syndrome occurring as a late complication following cytotoxic therapy.1â5 The term âtherapy-relatedâ leukemia is descriptive and based on a patientâs history of exposure to cytotoxic agents.
The relationships between clonal architecture and functional heterogeneity in acute myeloid leukemia (AML) samples are not yet clear. We used targeted sequencing to track AML subclones identified by whole-genome sequencing using a variety of experimental approaches.