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What Is Atripla? Atripla is a tablet that contains three antiretroviral drugs (ARVs) used to fight HIV: efavirenz (Sustiva), emtricitabine (Emtriva), and tenofovir (Viread). Atripla is manufactured by Gilead and Bristol-Myers Squibb. It is the first tablet that includes a complete antiretroviral regimen.
What are Protease Inhibitors (PIs)? When HIV infects a CD4 cell in a person's body, it copies its own genetic code into the cell's DNA. The CD4 cell is then programmed to make new HIV genetic material and HIV proteins. The proteins must be cut up by the HIV proteaseâa protein-cutting enzymeâto make functional new HIV particles.