Midazolam is ineffective for pain and has no analgesic effect during conscious sedation. The drug is a primary choice for conscious sedation because midazolam causes patients to have no recollection of the medical procedure.
Saffron is a plant. The dried stigmas (thread-like parts of the flower) are used to make saffron spice. It can take 75,000 saffron blossoms to produce a single pound of saffron spice. Saffron is largely cultivated and harvested by hand. Due to the amount of labor involved in harvesting, saffron is considered one of the world's most expensive spices. The stigmas are also used to make medicine. Saffron is used for asthma, cough, whooping cough (pertussis), and to loosen phlegm (as an expectorant).
Side effects. Using saffron supplements in the short-term seems safe for most people. They may cause side effects like anxiety, appetite changes, upset stomach, sleepiness, and headache. Using saffron in high doses or for long periods of time may be risky. Some people are also allergic to saffron.