a river in E Asia, forming most of the boundary between N Manchuria and the SE Russian Federation, flowing into the Sea of Okhotsk. About 2700 miles (4350 km) long.
High blood pressure is dangerous, partly because there are no symptoms, so organ damage can occur slowly without being recognized. Renal hypertension can cause chronic kidney disease. This is a slow decline in kidney function. Until the condition is well advanced, chronic kidney disease also causes no symptoms. Because there are usually no symptoms, a doctor may suspect renal hypertension when someone has uncontrolled high blood pressure despite multiple medications or has unexplained chronic kidney disease.
Damaged kidneys fail to regulate blood pressure. Healthy kidneys produce a hormone called aldosterone to help the body regulate blood pressure. Kidney damage and uncontrolled high blood pressure each contribute to a negative spiral. As more arteries become blocked and stop functioning, the kidneys eventually fail.