Dangers and Long-Term Effects of Cocaine Abuse. Risk of overdose, damage to the nose and nasal passages, what are the long term effects of use? Cocaine addicts can develop a chronic runny nose and find that their ability to smell is impaired, and their ability to taste also decreased.
A cerebral vasospasm is the term used to describe when a brain artery or smaller brain blood vessels narrow. A blood vesselâs central lumen becomes narrow in response to the vessel wall contraction. This constriction prohibits blood flow.
Vasospasm is directed by local. and humoral responses, with resultant arterial con-. striction and blood flow reduction. Thrombocytes. contact damaged endothelium, and platelet adhesion. and aggregation begin. Intravascular velocity is altered. by cannula diameter and platelet adhesion.