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Follow Following Unfollow Pending Disabled. A answered. An alpha-blocker, also called alpha-adrenergic antagonist, is a substance that relaxes muscle tissue in blood vessels and in the prostate gland, which improves the flow of urine and blood.
Uses [edit]. It is used in the treatment of hypertension, and specifically that caused by pheochromocytoma. It has a slower onset and a longer lasting effect compared with other alpha blockers.linically, non-selective alpha antagonists block alpha receptors (but do not differentiate between alpha-1 and alpha-2). They are used as antihypertensives because they block alpha-receptor-mediated vasoconstriction. The block on alpha-2 receptors further potentiates beta-effects, increasing cardiac output.