Lone Rock Beach and Horseshoe Bend in Page, Arizona. After we left Holbrook, we headed over towards Flagstaff, Arizona to stock up on some supplies and do some housekeeping.
Glycolysis involves nine distinct reactions that convert glucose into pyruvate. In this section, we will cover the first four of these reactions, which convert glucose into glyceraldehyde-3-phosphate.
Pyruvate enters the Krebs cycle via an intermediate called acetyl CoA. Pyruvate is formed in the cytoplasm as the end product of glycolysis. Pyruvate enters a mitochondrion, in the matrix of which it encounters the enzyme pyruvate dehydrogenase. This enzyme catalyzes the reaction of pyruvate with coenzyme A to form acetyl CoA. This reaction is sometimes called the link reaction, as it links glycolysis to the Krebs cycle (= citric acid cycle, or tricarboxylic acid cycle).