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As a general rule, antibiotics do not cause a decrease of white blood cells (WBCs). WBCs are one of the main ways the body fights infection. Because your son had a recent illness the WBC count most likely increased during that period in order to fight his infection.
Antibiotics differ in the types of bacteria they work against. Antibiotics that affect a wide range of bacteria are called broad spectrum antibiotics (e.g. amoxycillin and gentamicin). Antibiotics that affect only a few types of bacteria are called narrow spectrum antibiotics (e.g. penicillin).