The liver is the largest internal organ of the body and is located in the right upper quadrant of the abdomen, beneath the diaphragm and is protected by the lower right ribs. It also extends across the midline toward the left upper quadrant of the abdomen.he liver is the largest internal organ of the body and is located in the right upper quadrant of the abdomen, beneath the diaphragm and is protected by the lower right ribs. It also extends across the midline toward the left upper quadrant of the abdomen.
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