From Wikipedia, the free encyclopedia. An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B cells, or T cells. conformational epitope is composed of discontinuous sections of the antigen's amino acid sequence. These epitopes interact with the paratope based on the 3-D surface features and shape or tertiary structure of the antigen. The proportion of epitopes that are conformational is unknown.
Dear fortysomething: Yes, we do get questions about itchy nipples or burning nipples. The least common causes, but the most serious, would be inflammatory breast cancer or Paget's Disease (another type of breast cancer).
Tweezer type of Nipple clamp. Clover clamps. A nipple clamp is a clamp that can be applied to the nipples of any type of body. It is a sex toy which can be attached to the nipples to create pain by restricting blood flow from erect nipples by applying pressure to them. Some people derive erotic pleasure from seeing nipple clamps applied.