From Wikipedia, the free encyclopedia. An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B cells, or T cells. conformational epitope is composed of discontinuous sections of the antigen's amino acid sequence. These epitopes interact with the paratope based on the 3-D surface features and shape or tertiary structure of the antigen. The proportion of epitopes that are conformational is unknown.
Dear fortysomething: Yes, we do get questions about itchy nipples or burning nipples. The least common causes, but the most serious, would be inflammatory breast cancer or Paget's Disease (another type of breast cancer).
1 Breast abscess. 2  Breast cancer. 3  Breast duct cancer. 4  Breast duct papilloma-bleeding from nipple. 5  Breast feeding. 6  Paget's disease of nipple-can cause a bloody nipple discharge. 7  Piercing. 8  See causes of nipple discharge, breast pain, breast lump, or other breast symptoms.