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Coagulase is a protein enzyme produced by several microorganisms that enables the conversion of fibrinogen to fibrin. In the laboratory, it is used to distinguish between different types of Staphylococcus isolates. Importantly, S. aureus is generally coagulase-positive, meaning that coagulase negativity usually excludes S. aureus. However it is now known that not all S. aureus are coagulase-positive.
Microbiology is the study of microscopic organisms, such as fungi and bacteria. A microbiologist works primarily in a laboratory, analyzing the structure and processes of microorganisms, cellular tissue, proteins, and biological medicines.