Sphere of influence. In the field of international relations, a sphere of influence (SOI) is a spatial region or concept division over which a state or organization has a level of cultural, economic, military, or political exclusivity, accommodating to the interests of powers outside the borders of the state that controls it.
Multiple myeloma is named for the clock face appearance of these cancer cells when seen under a microscope. They infiltrate virtually all of a patient's bone marrow. In x-ray images of multiple myeloma, it looks like holes have been punched out of the bone.
Multiple Myeloma Symptoms. Multiple myeloma symptoms may vary by patient, with the early stages of myeloma often presenting no visible symptoms or signs. When present, the symptoms of multiple myeloma may be vague or similar to those of the other conditions. Certain multiple myeloma symptoms may also be associated with complications of the disease.