manifest. 1  readily perceived by the eye or the understanding; evident; obvious; apparent; plain: a manifest error. 2  Psychoanalysis. of or relating to conscious feelings, ideas, and impulses that contain repressed psychic material: the manifest content of a dream as opposed to the latent content that it conceals.
In medicine, an adverse effect is an undesired harmful effect resulting from a medication or other intervention such as surgery. An adverse effect may be termed a  side effect , when judged to be secondary to a main or therapeutic effect.
As with most drugs, chemotherapy drugs do have side effects. Side effects of chemotherapy are unwanted things that happen as a direct result of taking a drug. It is easy to confuse drug side effects with symptoms of cancer.Symptoms are the things that happen as a direct result of the cancer and have nothing to do with the drug.he side effects of chemotherapy can be unpleasant. But it can help to try to see the problems in relation to the benefits of the treatment. Chemotherapy does not cause side effects in everyone. It causes different reactions in different people. Remember-almost all side effects are temporary.