Do not take more than three doses (36 mg) of tizanidine in a 24-hour period. Too much of this medication can damage your liver. Cold or allergy medicine, narcotic pain medicine, sleeping pills, other muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by tizanidine.Tell your doctor if you need to use any of these other medicines together with tizanidine.Avoid drinking alcohol.old or allergy medicine, narcotic pain medicine, sleeping pills, other muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by tizanidine. Tell your doctor if you need to use any of these other medicines together with tizanidine. Avoid drinking alcohol.
If there are many more acidic residues than basic ones, the protein will have an overall negative charge. ....it is the phosphate groups that contain a negatively charged oxygen atom that make the DNA n RNA molecules negatively charged......
Salt, which is used along with ethanol to force DNA to precipitate, interacts with DNA molecules to make it much less hydrophilic. Ethanol makes it easier for this interaction to take place. DNA is hydrophilic because of the negatively charged phosphate groups found along its sugar phosphate backbone.