Note 2: Denaturation can occur when proteins and nucleic acids are subjected to elevated temperature or to extremes of pH, or to nonphysiological concentrations of salt, organic solvents, urea, or other chemical agents. Note 3: An enzyme loses its catalytic activity when it is denaturized.ote 2: Denaturation can occur when proteins and nucleic acids are subjected to elevated temperature or to extremes of pH, or to nonphysiological concentrations of salt, organic solvents, urea, or other chemical agents. Note 3: An enzyme loses its catalytic activity when it is denaturized.
List of Major League Baseball single-game hits leaders. Wilbert Robinson (left) and Rennie Stennett (not pictured) hold the record for most hits in a nine-inning game with seven, while Cal McVey (right) amassed six hits in each of two consecutive games.
Two Mariners players currently hold Major League Baseball records. Ichiro holds the record for most single-season hits and singles, obtaining both in 2004. Mike Cameron is tied with 14 others for the most home runs in a game, with four.