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ESBL stands for Extended-Spectrum beta-Lactamase. Beta lactamases are enzymes that are produced by many types of bacteria (germs) which make them more resistant to antibiotics and can make the infection harder to treat.
Beta-lactam antibiotics include penicillins, cephalosporins and related compounds. As a group, these drugs are active against many gram-positive, gram-negative and anaerobic organisms.acterial resistance against beta-lactam antibiotics is increasing at a significant rate and has become a common problem in primary care medicine. There are several mechanisms of antimicrobial resistance to beta-lactam antibiotics.