In other words: A Permutation is an ordered Combination. There are basically two types of permutation: 1  Repetition is Allowed: such as the lock above. It could be 333.  No Repetition: for example the first three people in a running race. You can't be first and second.
For this reason, the idea that collagen supplementation can be an effective treatment for joint pain, osteoarthritis, or any other condition, is highly implausible, if not impossible in principle.
Collagen is a protein that is part of cartilage, bone, and other tissues in animals and humans. People use collagen from chickens for medicine. Chicken collagen is used to treat joint pain associated with many types of arthritis and surgery, as well as back pain, neck pain, and pain following injury.Chicken collagen is said to work by causing the body to produce substances that fight pain and swelling (inflammation), but this is unproven.ince collagen type II contains chondroitin and glucosamine, large doses might lead to the same side effects as those seen with chondroitin and glucosamine supplements. These side effects include nausea, heartburn, diarrhea and constipation, drowsiness, skin reactions, and headache.