Practice Essentials. Psoriasis is a complex, chronic, multifactorial, inflammatory disease that involves hyperproliferation of the keratinocytes in the epidermis, with an increase in the epidermal cell turnover rate (see the image below).
I have gout and high blood pressure. My gout, which is not triggered by high uric acid levels, is controlled by daily colchicine.For my blood pressure, which uncontrolled would be in the 200 over 100+ range, I take nifedipine 60mg daily, atenolol 25 mg daily, and clonidine .1 mg at midnight and .05 mg at noon.My typical B.P. is 158 over 78, pulse 48.ead More. He has been on cyclosporine, imuran, toprol, clonidine, and many other drugs for 10 years. He is hospitalized at this this time and so far the doctors can not find a reason for his symptons. His breathing is very labored (breathing from his stomach) he had a severe case of gout in his hand and elbow.
1 Colchicine, to prevent flare-ups during the first months that you are taking medicines that lower uric acid.  Pegloticase (Krystexxa). This medicine is for gout that has lasted a long time and hasn't responded to other treatment.