Note 2: Denaturation can occur when proteins and nucleic acids are subjected to elevated temperature or to extremes of pH, or to nonphysiological concentrations of salt, organic solvents, urea, or other chemical agents. Note 3: An enzyme loses its catalytic activity when it is denaturized.ote 2: Denaturation can occur when proteins and nucleic acids are subjected to elevated temperature or to extremes of pH, or to nonphysiological concentrations of salt, organic solvents, urea, or other chemical agents. Note 3: An enzyme loses its catalytic activity when it is denaturized.
List of Major League Baseball single-game hits leaders. Wilbert Robinson (left) and Rennie Stennett (not pictured) hold the record for most hits in a nine-inning game with seven, while Cal McVey (right) amassed six hits in each of two consecutive games.
Ichiro set the single-season mark for most hits in a season back in 2004 with 262. That surpassed the previous record, established back in 1920 by George Sisler. Ichiro has recorded 10 seasons of at least 200 hits in his career, tied for the most in baseball history with Pete Rose.