In other words: A Permutation is an ordered Combination. There are basically two types of permutation: 1  Repetition is Allowed: such as the lock above. It could be 333.  No Repetition: for example the first three people in a running race. You can't be first and second.
For this reason, the idea that collagen supplementation can be an effective treatment for joint pain, osteoarthritis, or any other condition, is highly implausible, if not impossible in principle.
Collagen helps shape tissue and keep it strong and firm. This fibrous protein is everywhere: in tendons, muscles, bone, cartilage and skin. Over time, the amount of collagen in the body decreases, leading to sagging skin and deteriorating bones. Collagen supplements are supposed to reverse this natural loss.