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Cause (including risk factors) Charcot foot occurs in patients with peripheral neuropathy resulting from diverse conditions including diabetes mellitus, leprosy, syphilis, poliomyelitis, chronic alcoholism or syringomyelia. Repetitive microtrauma that exceeds the rate of healing may cause fractures and dislocations.
Delays in diagnosing Charcot foot may be owed to: 1  The symptoms, which are non-specific, are also signs of infection or arthritic conditions. 2  People with neuropathy may lose sensation in their feet and not feel the pain of fractured or dislocated bones.