Note 2: Denaturation can occur when proteins and nucleic acids are subjected to elevated temperature or to extremes of pH, or to nonphysiological concentrations of salt, organic solvents, urea, or other chemical agents. Note 3: An enzyme loses its catalytic activity when it is denaturized.ote 2: Denaturation can occur when proteins and nucleic acids are subjected to elevated temperature or to extremes of pH, or to nonphysiological concentrations of salt, organic solvents, urea, or other chemical agents. Note 3: An enzyme loses its catalytic activity when it is denaturized.
List of Major League Baseball single-game hits leaders. Wilbert Robinson (left) and Rennie Stennett (not pictured) hold the record for most hits in a nine-inning game with seven, while Cal McVey (right) amassed six hits in each of two consecutive games.
Players to hit four home runs in a Major League Baseball game are highlighted in red. 1  John C. Crooks of the Omahogs went 5-5 with 4 home runs and a single. 2  Pawtucket first baseman Daniel F. Cronin had 4 home runs.  Robert L. Lowe of the Beaneaters had 4 home runs.