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Klassen was born in Winnipeg, Manitoba, Canada, in 1981 and grew up in Niagara Falls and Toronto, Ontario. He studied animation at Sheridan College, graduated in 2005, and moved to Los Angeles. That year he made an animated short with Daniel Rodrigues, An Eye for Annai.
Van Susteren (Dutch for from Susteren) was born in Appleton, Wisconsin. Her father, Urban Van Susteren, was of Dutch descent. Her mother, born Margery (Conway), was a homemaker of Irish descent. Van Susteren's father was a longtime friend of future U.S. Senator Joseph McCarthy. McCarthy was best man at Greta Van Susteren's parents' wedding. Urban Van Susteren, an elected judge, served as a campaign strategist for McCarthy, although Urban later broke with him. Van Susteren's sister, Lise, is a forensic psychiatrist in Bethesda, Maryland.