I took clindamycin 150mg a week ago for an ear infection (twice ...I am generally very allergic to antibiotics. ...I am now a week later feeling worse, I'm tired and my left leg is feeling very tingly..
The exact cause is not known, but could be related to an allergy to sweat itself. Sweat triggers the release of histamine causing itchiness in the legs or other parts of the body. It may also present with warm skin and small (up to 2-3 mm) bumps, which usually persist from 30 minutes to 2 hours. Some people may respond with a positive patch test to their own sweat.
Another possible cause of burning legs is meralgia paresthetica, which is pain in the outer thigh due to compression of the lateral femoral cutaneous nerve, one of the main nerves within the thigh. Chronic conditions, such as multiple sclerosis, can also cause the sensation of burning in the legs.