Sphere of influence. In the field of international relations, a sphere of influence (SOI) is a spatial region or concept division over which a state or organization has a level of cultural, economic, military, or political exclusivity, accommodating to the interests of powers outside the borders of the state that controls it.
Multiple myeloma is named for the clock face appearance of these cancer cells when seen under a microscope. They infiltrate virtually all of a patient's bone marrow. In x-ray images of multiple myeloma, it looks like holes have been punched out of the bone.
This term is used to mean early myeloma that is not causing any symptoms or problems. People with smoldering myeloma have some signs of multiple myeloma, such as any of the following. 1  Plasma cells in the bone marrow between 10 and 60%. 2  High level of monoclonal immunoglobulin (M protein) in the blood.eople with smoldering myeloma have some signs of multiple myeloma, such as any of the following. 1  Plasma cells in the bone marrow between 10 and 60%. 2  High level of monoclonal immunoglobulin (M protein) in the blood.