Ground substance is the background material within which all other connective tissue elements are embedded. In ordinary connective tissue, the ground substance consists mainly of water whose major role is to provide a route for communication and transport (by diffusion) between tissues.
Definitions for tiredness. Here are all the possible meanings and translations of the word tiredness. Princeton's WordNet(0.00 / 0 votes)Rate this definition: fatigue, weariness, tiredness(noun) temporary loss of strength and energy resulting from hard physical or mental work. he was hospitalized for extreme fatigue; growing fatigue was apparent from the decline in the execution of their athletic skills; weariness overcame her after twelve hours and she fell asleep.
Fatigue is a feeling of exhaustion, tiredness, weariness or lack of energy. After TBI, you may have more than one kind of fatigue: 1  Physical fatigue: âIâm tired and I need to rest. 2  Iâm dragging today.â. 3  Psychological fatigue: âI just canât get motivated to do anything. 4  Being depressed wears me out; I just donât feel like doing anything.â.