In other words: A Permutation is an ordered Combination. There are basically two types of permutation: 1  Repetition is Allowed: such as the lock above. It could be 333.  No Repetition: for example the first three people in a running race. You can't be first and second.
For this reason, the idea that collagen supplementation can be an effective treatment for joint pain, osteoarthritis, or any other condition, is highly implausible, if not impossible in principle.
Overview. Collagen is a fibrous protein that functions as a building block for skin, tendons, joints, other connective tissues and bones. Collagen also keeps skin, bones, teeth and blood vessels healthy. Taking collagen supplements helps replenish and replace natural collagen, which decreases with age.