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Canker sores may also occur because of certain conditions and diseases, such as: 1  Celiac disease, a serious intestinal disorder caused by a sensitivity to gluten, a protein found in most grains. 2  Inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis.
The two main types of canker sores are complex canker sores and simple canker sores. Complex canker sores is the less common type of canker sore and tends to appear in people who have a history of canker sores. Simple canker sores are common among people aged 10 years old to 20 years old.