The most common cause of a pulmonary embolism is a blood clot (thrombus) in a large leg vein of the leg that breaks off and travels to the lungs (embolus).An embolus may be from clots in other parts of the body.Or they may be made up of other solids, liquids, or gases that travel to the lungs.he most common cause of a pulmonary embolism is a blood clot (thrombus) in a large leg vein of the leg that breaks off and travels to the lungs (embolus).
Ambrisentan is an endothelin receptor antagonist indicated for pulmonary arterial hypertension in patients with WHO class II or III symptoms. It improves exercise ability and decreases progression of clinical symptoms.
Pulmonary Arterial Hypertension. Pulmonary arterial hypertension (PAH) is a rare form of high blood pressure. It occurs in the pulmonary arteries that flow from your heart and through your lungs. Constricted and narrowed arteries prevent your heart from pumping adequate blood. When constriction occurs, the heart will need to work harder to compensate.