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Actos (pioglitazone) is an oral diabetes medicine that helps control blood sugar levels. Actos is for people with type 2 diabetes. Actos is not for treating type 1 diabetes. You should not use Actos if you have severe or uncontrolled heart failure, active bladder cancer, or diabetic ketoacidosis (call your doctor for treatment with insulin). This medicine is not for treating type 1 diabetes.
If any of the following signs or symptoms are seen upon treatment with Actos, patients are advised to contact their physicians or health care professionals as these symptoms may potentially indicate bladder cancer: 1  Blood in the urine or red-colored urine. 2  New or increasing urge to urine. 3  Pain when urinating.