Sphere of influence. In the field of international relations, a sphere of influence (SOI) is a spatial region or concept division over which a state or organization has a level of cultural, economic, military, or political exclusivity, accommodating to the interests of powers outside the borders of the state that controls it.
Multiple myeloma is named for the clock face appearance of these cancer cells when seen under a microscope. They infiltrate virtually all of a patient's bone marrow. In x-ray images of multiple myeloma, it looks like holes have been punched out of the bone.
What is Smoldering Myeloma? Smoldering multiple myeloma (SMM) is a precancerous form of myeloma, a cancer of plasma cells in the bone marrow. SMM is characterized by the presence in the blood of an abnormal protein produced by plasma cells and the presence of free light chains in the blood or urine. The abnormal protein is referred to as an Mâprotein or paraprotein.