Any disease that causes extensive damage to the pancreas may lead to diabetes (for example, chronic pancreatitis and cystic fibrosis). Diseases associated with excessive secretion of insulin-antagonistic hormones can cause diabetes (which is typically resolved once the hormone excess is removed). This form was previously referred to as insulin-dependent diabetes mellitus (IDDM) or juvenile diabetes. 2  The cause is unknown. 3  Type 2 DM begins with insulin resistance, a condition in which cells fail to respond to insulin properly. 4  As the disease progresses a lack of insulin may also develop.
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The recommended adult oral dose for erosive esophagitis is 40 mg once a day for up to eight weeks. An additional eight-week course may be considered for those patients who have not healed after eight weeks. The safety and efficacy of pantoprazole for maintenance therapy (beyond 16 weeks) have not been established.he recommended adult oral dose for erosive esophagitis is 40 mg once a day for up to eight weeks. An additional eight-week course may be considered for those patients who have not healed after eight weeks. The safety and efficacy of pantoprazole for maintenance therapy (beyond 16 weeks) have not been established.