What is Quad Screening? Quad Screening is a prenatal test to determine the likelihood that a fetus (unborn baby) is affected with trisomy 21 (Down syndrome), trisomy 18, and certain types of birth defects (open neural tube defect or abdominal wall defects). Chromosome abnormalities (e.g. trisomy 21, trisomy 18) occur more frequently as a woman ages.
(From bottom left to bottom right) Michael Fishman as D.J. Conner, Sara Gilbert as Darlene Conner, Roseanne Barr as Roseanne Conner, John Goodman as Dan Conner and Sarah Chalke as Becky Conner. The following is a list of major characters in the television series Roseanne.
Main article: Roseanne Conner. Played by Roseanne Barr. Roseanne, in a takeoff of her stand-up comedic and presumed real-life persona, is a bossy, loud, caustic, overweight, and dominant woman. She constantly tries to control the lives of her sister, husband, children, co-workers, and friends.