In other words: A Permutation is an ordered Combination. There are basically two types of permutation: 1  Repetition is Allowed: such as the lock above. It could be 333.  No Repetition: for example the first three people in a running race. You can't be first and second.
For this reason, the idea that collagen supplementation can be an effective treatment for joint pain, osteoarthritis, or any other condition, is highly implausible, if not impossible in principle.
Collagen is used to restore elasticity to the joints. Stiff joints are one of the side effects of aging, but an increase in collagen can reduce stiffness and even help arthritis symptoms fade by reducing inflammation and improving joint elasticity.