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A pinched sciatic nerve â or the nerve that originates in the lower part of your spine and runs the length of your leg â is the condition that arises when pressure is applied to this nerve. The sciatic nerve is the longest and thickest nerve in your body, so sciatic symptoms can be severe and debilitating.
What Is Sciatica? Sciatica is a severe pain in the leg caused by compression, irritation, or inflammation of the sciatic nerve. The sciatic nerves are the largest and longest nerves in the body, reaching about the size of your thumb in diameter, and running down the back of each leg.