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As a general rule, antibiotics do not cause a decrease of white blood cells (WBCs). WBCs are one of the main ways the body fights infection. Because your son had a recent illness the WBC count most likely increased during that period in order to fight his infection.
Antibiotics in the macrolide group affect ribosomes, the cellâs protein-building machines. Ribosomes build proteins in both bacteria and human cells, but there are differences between bacterial and human ribosomes. Macrolides block only bacterial ribosomes and prevent them from building proteins.