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ESBL stands for Extended-Spectrum beta-Lactamase. Beta lactamases are enzymes that are produced by many types of bacteria (germs) which make them more resistant to antibiotics and can make the infection harder to treat.
The sulfonylureas, like glucose, induce closure of KATP channels and stimulate insulin secretion. The beta-cell KATP channel is a complex octameric unit of 2 different proteins: the sulfonylurea receptor (SUR-1) and an inward rectifier (Kir6.2).