References. âµ 1  Zipes DP, Wellens HJ. Sudden cardiac death. âµ 2  Myerburg RJ, Interian AJ, Mitrani RM, Kessler KM, Castellanos A. Frequency of sudden cardiac death and profiles of risk. âµ 3  Connolly SJ, Hallstrom AP, Cappato R, Schron EB, Kuck KH, Zipes DP, Greene HL, Boczor S, Domanski M, Follmann D, Gent M, Roberts RS.
Rotavirus is a virus that causes diarrhea, mostly in babies and young children. The diarrhea can be severe, and lead to dehydration. Vomiting and fever are also common in babies with rotavirus. Before rotavirus vaccine, rotavirus disease was a common and serious health problem for children in the United States.
Genome Structure. The genome of the rotavirus is segmented and consists of eleven segments of linear double-stranded RNA. The complete genome is 16500-21000 nucleotides long. The 5'-terminal sequence has conserved regions; 5'-end of the genome has a methylated nucleotide cap.