Penalty for Non-Qualified Distributions. Distributions not used for qualified medical expenses are includable in gross income and, for applicants under age 65, subject to an additional 10% tax.
General Pharmacology. Beta-adrenoceptor agonists (Î²-agonists) bind to Î²-receptors on cardiac and smooth muscle tissues. They also have important actions in other tissues, especially bronchial smooth muscle (relaxation), the liver (stimulate glycogenolysis) and kidneys (stimulate renin release). Beta-adrenoceptors normally bind to norepinephrine released by sympathetic adrenergic nerves, and to circulating epinephrine.
Serotonin-norepinephrine reuptake inhibitors (SNRIs) also inhibit the reuptake of serotonin. In addition, they inhibit the re-absorption of another neurotransmitter called nor-epinephrine. Just like serotonin is associated with positive feelings, nor-epinephrine is associated with alertness and energy.