In other words: A Permutation is an ordered Combination. There are basically two types of permutation: 1  Repetition is Allowed: such as the lock above. It could be 333.  No Repetition: for example the first three people in a running race. You can't be first and second.
For this reason, the idea that collagen supplementation can be an effective treatment for joint pain, osteoarthritis, or any other condition, is highly implausible, if not impossible in principle.
Bone Health. Several studies on collagen, which represents 90% of organic bone mass, suggest that orally administering collagen peptides may provide beneficial effects on bone metabolism, especially in the calcium-deficient condition such as osteopenia, without obvious undesirable effects.