My other thought is that some medications have short term memory problems as a side effect. Is your brother on any medications ? If her is, he could go to www.drugs.com , type in the name of the drug and see if memory issues are a side effect. Finally, is your brother having sleeping problems ?
For some vehicles, you're advised to change the coolant every 30,000 miles. For others, changing the coolant isn't even on the maintenance schedule. For example, Hyundai says the coolant (what many refer to as antifreeze) in most of its models should be replaced after the first 60,000 miles, then every 30,000 miles after that. The interval is every 30,000 miles on some Mercedes-Benz models, but on others it's 120,000 miles or 12 years.
It is a good practice to change the coolant every 25,000-40,000 miles. Replacing the coolant will ensure it is free of contaminants such as rust or scale that can block it from flowing through the radiator and engine. Given high engine temperatures, it is inevitable that the tanks in the radiator will eventually crack.