Rheumatoid arthritis is a serious autoimmune disease that attacks the joints and other body parts. But RA can be tough to diagnose. Symptoms can mimic other illnesses, or they may flare, then fade, only to flare again somewhere else. Lab tests arenât perfectyou can test negative for RA factors and still have it.heumatoid arthritis is a serious autoimmune disease that attacks the joints and other body parts. But RA can be tough to diagnose. Symptoms can mimic other illnesses, or they may flare, then fade, only to flare again somewhere else. Lab tests arenât perfectyou can test negative for RA factors and still have it.
People with pyruvate dehydrogenase deficiency usually have neurological problems as well. Most have delayed development of mental abilities and motor skills such as sitting and walking. Other neurological problems can include intellectual disability, seizures, weak muscle tone (hypotonia), poor coordination, and difficulty walking.
What are the symptoms of dehydration? The degree of dehydration is graded according to signs and symptoms that reflect the amount of fluid lost: In the early stages of dehydration, there are no signs or symptoms.Early features are difficult to detect but include dryness of mouth and thirst. As dehydration increases, signs and symptoms develop.These include: thirst, restless or irritable behaviour, decreased skin turgor, dry mucous membranes, sunken eyes, sunken fontanelle (in infants), and absence of tears when crying vigorously. Symptoms of early or mild dehydration include:1  flushed face. 2  extreme thirst, more than normal or unable to drink. 3  dry, warm skin. 4  cannot pass urine or reduced amounts, dark, yellow. 5  dizziness made worse when you are standing. 6  weakness. 7  cramping in the arms and legs. 8  crying with few or no tears.ymptoms of early or mild dehydration include: 1  flushed face. 2  extreme thirst, more than normal or unable to drink. 3  dry, warm skin. 4  cannot pass urine or reduced amounts, dark, yellow. 5  dizziness made worse when you are standing. 6  weakness.