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1. stoichiometry - (chemistry) the relation between the quantities of substances that take part in a reaction or form a compound (typically a ratio of whole integers).
sterâ¢eâ¢oâ¢chemâ¢isâ¢try. the branch of chemistry that deals with the determination of the relative positions in space of the atoms or groups of atoms in a compound and with the effects of these positions on the properties of the compound.