Ground substance is the background material within which all other connective tissue elements are embedded. In ordinary connective tissue, the ground substance consists mainly of water whose major role is to provide a route for communication and transport (by diffusion) between tissues.
Definitions for tiredness. Here are all the possible meanings and translations of the word tiredness. Princeton's WordNet(0.00 / 0 votes)Rate this definition: fatigue, weariness, tiredness(noun) temporary loss of strength and energy resulting from hard physical or mental work. he was hospitalized for extreme fatigue; growing fatigue was apparent from the decline in the execution of their athletic skills; weariness overcame her after twelve hours and she fell asleep.
Fatigue is a feeling of tiredness, exhaustion, or lack of energy. You may feel mildly fatigued because of overwork, poor sleep, worry, boredom, or lack of exercise. Any illness, such as a cold or the flu, may cause fatigue, which usually goes away as the illness clears up. Guillain-Barre barrÃ©, syndrome a rare nerve disorder that causes weakness in the, legs, arms and other muscles and that can progress to complete. 2  Paralysis myasthenia, gravis a, rare chronic disorder that causes weakness and rapid muscle.  fatigue