manifest. 1  readily perceived by the eye or the understanding; evident; obvious; apparent; plain: a manifest error. 2  Psychoanalysis. of or relating to conscious feelings, ideas, and impulses that contain repressed psychic material: the manifest content of a dream as opposed to the latent content that it conceals.
In medicine, an adverse effect is an undesired harmful effect resulting from a medication or other intervention such as surgery. An adverse effect may be termed a  side effect , when judged to be secondary to a main or therapeutic effect.
Side Effects of Cold Medicine. While cold medicines are helpful in relieving many of the symptoms related to the common cold, they can cause a variety of side effects as well. Over-the-counter cold medicines are usually a combination of drugs depending on the symptoms. Each medication can cause a different range of side effects. Consult your physician before taking cold medicines if you suffer from a heart condition, kidney disease, glaucoma, or other medical condition.