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Changes in the urinary system during pregnancy. The body goes through many changes during pregnancy. Significant anatomical changes occur in the urinary system. Under the influence of the hormone progesterone, the kidneys and the ureters dilate. This can lead to a slow down in the flow of urine through the ureters and therefore an increased risk of urinary infection in pregnancy.
Renal tubular dysgenesis is characterized by abnormal kidney development before birth, the inability to produce urine (anuria), and severe low blood pressure (hypotension). These problems result in a reduction of amniotic fluid (oligohydramnios), which leads to a set of birth defects known as the Potter sequence.