manifest. 1  readily perceived by the eye or the understanding; evident; obvious; apparent; plain: a manifest error. 2  Psychoanalysis. of or relating to conscious feelings, ideas, and impulses that contain repressed psychic material: the manifest content of a dream as opposed to the latent content that it conceals.
In medicine, an adverse effect is an undesired harmful effect resulting from a medication or other intervention such as surgery. An adverse effect may be termed a  side effect , when judged to be secondary to a main or therapeutic effect.
Side Effects. Drug information provided by: Micromedex. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: Less common. Confusion.