From Wikipedia, the free encyclopedia. An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B cells, or T cells. conformational epitope is composed of discontinuous sections of the antigen's amino acid sequence. These epitopes interact with the paratope based on the 3-D surface features and shape or tertiary structure of the antigen. The proportion of epitopes that are conformational is unknown.
Dear fortysomething: Yes, we do get questions about itchy nipples or burning nipples. The least common causes, but the most serious, would be inflammatory breast cancer or Paget's Disease (another type of breast cancer).
Causes of inverted nipples - What are common causes of inverted nipples? Many causes. Inverted nipples maybe natural. Maybe due to previous episodes of infection/mastitis, physiological or secondary to an underlying malignancy. If you have noted inversion of your nipple, you need to have an evaluation by a health care provider experienced in breast care. Breast cancer needs to be ruled out.