Hereditary neuropathies are diseases of the peripheral nerves that are genetically passed from parent to child. The most common of these is Charcot-Marie-Tooth disease type 1. It is characterized by weakness in the legs and, to a lesser degree, the arms -- symptoms that usually appear between mid-childhood and age 30.
1 Chlorine ions are colored yellow in the VRML model. 2  Sodium (Na +) and potassium (K +) are positive ions. 3  They are found on both sides of the membrane. 4  Na + ions are in greater concentration outside the neuron whereas K + ions are more concentrated inside the neuron. 5  Na + ions are colored pink in the VRML model.
Sodium and chloride also help to determine the resting potential. Sodium is positive and has a concentration gradient set up to flow INTO the cell, and chloride is negative and has a concentration gradient set up to flow INTO the cell. The resting conductance for these two ions is less than that of potassium, but is not zero. Their story (concentration gradient + electrical gradient) is very similar to that of potassium. These ions together determine the resting potential of the cell.