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There are several types of acute nephritis: In interstitial nephritis, the spaces between the kidney tubules become inflamed. This inflammation causes the kidneys to swell. Pyelonephritis is an inflammation of the kidney, usually due to a bacterial infection. In the majority of cases, the infection starts within the bladder and then migrates up the ureters and into the kidneys. Ureters are two tubes that transport urine from each kidney to the bladder.
Pyelonephritis may start with similar symptoms. However, once the infection has spread to the kidney, signs of more severe illness usually result. They include: 1  Back pain or flank pain. 2  Fever (usually present) or chills. 3  Feeling sick (malaise). 4  Nausea and vomiting. 5  Confusion (especially in the elderly).