In other words: A Permutation is an ordered Combination. There are basically two types of permutation: 1  Repetition is Allowed: such as the lock above. It could be 333.  No Repetition: for example the first three people in a running race. You can't be first and second.
For this reason, the idea that collagen supplementation can be an effective treatment for joint pain, osteoarthritis, or any other condition, is highly implausible, if not impossible in principle.
This is because collagen molecules are too big to be absorbed through the skin. That doesnât mean collagen isnât really beneficial though, just that we have to get it from the inside out. Collagen (and gelatin) are naturally found in high quality broth and in cuts of meat that contain skin or bone. If youâve ever made bone broth and had it âgelâ when it cooled, this is due to the gelatin and collagen naturally present in the bones. The particular amino acids in collagen are said to be especially beneficial in the body for: 1  Supporting hair, skin and nails. 2  For joint health. 3  To encourage skin elasticity and reduce the signs of aging. 4  Improving digestion. 5  As a protein source.