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Canker sores may also occur because of certain conditions and diseases, such as: 1  Celiac disease, a serious intestinal disorder caused by a sensitivity to gluten, a protein found in most grains. 2  Inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis.
1 Canker sores are small, painful ulcers on the inside of the mouth, tongue, lips, or throat. 2  Symptoms of canker sores include small, painful, crater-like ulcers.3  See a doctor if canker sores are accompanied by fever, last more than three weeks, or the affected individual has difficulty swallowing. Symptoms of canker sores include small, painful, crater-like ulcers. 2  See a doctor if canker sores are accompanied by fever, last more than three weeks, or the affected individual has difficulty swallowing.