Sphere of influence. In the field of international relations, a sphere of influence (SOI) is a spatial region or concept division over which a state or organization has a level of cultural, economic, military, or political exclusivity, accommodating to the interests of powers outside the borders of the state that controls it.
Multiple myeloma is named for the clock face appearance of these cancer cells when seen under a microscope. They infiltrate virtually all of a patient's bone marrow. In x-ray images of multiple myeloma, it looks like holes have been punched out of the bone.
Melanoma is a kind of skin cancer. It isn't as common as other types of skin cancer, but it is the most serious. Melanoma usually looks like a flat mole with uneven edges and a shape that is not the same on both sides. It may be black, brown, or more than one color.Most melanomas show up as a new spot or skin growth.ut they can form in an existing mole or other mark on the skin. Melanoma can affect your skin only, or it may spread to your organs and bones. As with other cancers, treatment for melanoma works best when the cancer is found early.