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General Pharmacology. Beta-adrenoceptor agonists (Î²-agonists) bind to Î²-receptors on cardiac and smooth muscle tissues. They also have important actions in other tissues, especially bronchial smooth muscle (relaxation), the liver (stimulate glycogenolysis) and kidneys (stimulate renin release). Beta-adrenoceptors normally bind to norepinephrine released by sympathetic adrenergic nerves, and to circulating epinephrine.
Norepinephrine. In addition to epinephrine, we see norepinephrine, which is a second hormone secreted by the adrenal medulla that increases heart rate, blood pressure, cardiac output and blood glucose levels.So we see that norepinephrine is very similar to epinephrine.t the center of the adrenal glands we see the adrenal medulla. This portion of the gland is stimulated by the sympathetic nervous system to secrete catecholamines, which are hormones that help you deal with short-term stress. There are two catecholamines. One is called epinephrine or adrenaline.