Note 2: Denaturation can occur when proteins and nucleic acids are subjected to elevated temperature or to extremes of pH, or to nonphysiological concentrations of salt, organic solvents, urea, or other chemical agents. Note 3: An enzyme loses its catalytic activity when it is denaturized.ote 2: Denaturation can occur when proteins and nucleic acids are subjected to elevated temperature or to extremes of pH, or to nonphysiological concentrations of salt, organic solvents, urea, or other chemical agents. Note 3: An enzyme loses its catalytic activity when it is denaturized.
List of Major League Baseball single-game hits leaders. Wilbert Robinson (left) and Rennie Stennett (not pictured) hold the record for most hits in a nine-inning game with seven, while Cal McVey (right) amassed six hits in each of two consecutive games.
All told, when you add together Minnie Minoso's Major League (1,963), minor league (429), Cuban League (838), Mexican League (715) and Negro League hits (at least 128 documented), he winds up with a career total of 4,073 professional hits.