In other words: A Permutation is an ordered Combination. There are basically two types of permutation: 1  Repetition is Allowed: such as the lock above. It could be 333.  No Repetition: for example the first three people in a running race. You can't be first and second.
For this reason, the idea that collagen supplementation can be an effective treatment for joint pain, osteoarthritis, or any other condition, is highly implausible, if not impossible in principle.
Collagen certainly is necessary for the body to survive. Without it, all the connective tissues in the body suffer â the muscles, tendons, ligaments, cartilage and bones. Even the tissues that surround the internal organs and hold them together need collagen.