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Down syndrome and trisomy 18. Benefits of first trimester screening include earlier identification of the pregnancy. at risk for fetal aneuploidy and anatomic defects, in particular, cardiac anomalies, and the option of earlier. diagnosis by chorionic villus sampling, if available.
There are four basic types of screening tests for Down syndrome. Some of these tests need to be done early in the pregnancy, while one is not done until 15 to 18 weeks of pregnancy (at around 4 months). âFirst-trimester screening is typically done at 11 to 13 weeks of pregnancy.