manifest. 1  readily perceived by the eye or the understanding; evident; obvious; apparent; plain: a manifest error. 2  Psychoanalysis. of or relating to conscious feelings, ideas, and impulses that contain repressed psychic material: the manifest content of a dream as opposed to the latent content that it conceals.
In medicine, an adverse effect is an undesired harmful effect resulting from a medication or other intervention such as surgery. An adverse effect may be termed a  side effect , when judged to be secondary to a main or therapeutic effect.
Constipation, increased thirst or increased gas levels in the body or known side effects which are associated with the use of this medication. It is important that if you do encounter any side effect whilst using this medication, that you inform your doctor immediately and consult them for further advice and guidance.