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High HDL. High levels of good, or HDL, cholesterol can significantly decrease a person's risk for heart disease. According to the latest guidelines, a level of 60 mg/dL and above is considered high.. In most cases, the cause is unknown, but it does seem to run in families. High HDL levels can also be caused by certain cholesterol medications, aerobic exercise, and regular alcohol consumption.
Interpreting HDL Cholesterol Levels. HDL levels below 40 mg/dL are associated with an increased risk of CAD, even in people whose total cholesterol and LDL cholesterol levels are normal. HDL levels between 40 and 60 mg/dL are considered normal, and do not very much affect the risk of CAD one way or the other.