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It is named after John Langdon Down, the British doctor who fully described the syndrome in 1866. Some aspects of the condition were described earlier by Jean-Ãtienne Dominique Esquirol in 1838 and Ãdouard SÃ©guin in 1844. In 1957, the genetic cause of Down syndrome, an extra copy of chromosome 21, was discovered.
John Muir. John Muir (21 April 1838 â 24 December 1914) was a Scottish-American naturalist, author, environmental philosopher and early advocate of preservation of wilderness in the United States. His letters, essays, and books telling of his adventures in nature, especially in the Sierra Nevada of California, have been read by millions.