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Best Answer: There is only a .2% change in the DNA of all breeds and that change is all in appearance... Anyway, the three breeds that are the closest to a wolf have to be a German Shepherd, Husky, and an Alaskan Malamute... Source(s): Capt. Jack Sparrow Â· 6 years ago.
Wolf hybrid aggression & features. A wolf hybrid is defined as an animal that is the immediate or remote descendant from the mating between a domestic dog and wolf. A wolf is not domesticated and therefore any dog mixed with wolf, known as a wolf hybrid, should not be considered âdomesticatedâ.