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Largest organ. Your skin is your largest organ. It covers your entire body and has a surface area of around 2 square metres. Its thickness varies from 0.5mm on your eyelids to 4mm or more on the palms of your hands and the soles of your feet. In total, it accounts for around 16 percent of your body weight.
The skin is the largest organ of the body, with a total area of about 20 square feet. The skin protects us from microbes and the elements, helps regulate body temperature, and permits the sensations of touch, heat, and cold.Skin has three layers: 1  The epidermis, the outermost layer of skin, provides a waterproof barrier and creates our skin tone.2  The dermis, beneath the epidermis, contains tough connective tissue, hair follicles, and sweat glands. 3  The deeper subcutaneous tissue (hypodermis) is made of fat and connective tissue.he skin protects us from microbes and the elements, helps regulate body temperature, and permits the sensations of touch, heat, and cold. Skin has three layers: 1  The epidermis, the outermost layer of skin, provides a waterproof barrier and creates our skin tone.