1 To establish the maximum tolerable dose of betahistine dihydrochloride (betahistine) within the range of 50 mg to 300 mg/day that appears to be effective for atypical depression. Are at significant risk of suicide as indicated by a score of 3 or greater on item number 11 on the HAM-D 28. 2  Have received any investigational product within 28 days of Screening. 3  Have used any antidepressant within 7 days of Screening (14 days for MAOIs; 21 days for fluoxetine).
Boulder Creek, California. Boulder Creek is a census-designated place (CDP) in Santa Cruz County, California, with a population of 4,923 as of the 2010 census.
Gold River is a census-designated place (CDP) in Sacramento County, California. The population was 7,812 at the 2010 census, down from 8,023 at the 2000 census. Gold River is part of the Sacramento â Arden-Arcade â Roseville Metropolitan Statistical Area. With a median family income of over $117,000, Gold River is the highest-income place in Sacramento County.