1 Examples are morphine and heroin. 2  Worldwide, an estimated 69 000 people die from opioid overdose each year.  There are an estimated 15 million people who suffer from opioid dependence (i.e. an addiction to opioids).
Berberine is a natural alkaloid found in a wide variety of traditional herbs including goldenseal, barberry and Oregon grape. Many herbalists credit this unique alkaloid for the benefits of ancient herbal tonics used by native populations throughout the world.
Thiamine is a vitamin, also called vitamin B1. Vitamin B1 is found in many foods including yeast, cereal grains, beans, nuts, and meat. It is often used in combination with other B vitamins, and found in many vitamin B complex formulations.hiamine is a vitamin, also called vitamin B1. Vitamin B1 is found in many foods including yeast, cereal grains, beans, nuts, and meat. It is often used in combination with other B vitamins, and found in many vitamin B complex formulations.