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Best Answer: There is only a .2% change in the DNA of all breeds and that change is all in appearance... Anyway, the three breeds that are the closest to a wolf have to be a German Shepherd, Husky, and an Alaskan Malamute... Source(s): Capt. Jack Sparrow Â· 6 years ago.
The dog, Canis familiaris, is a direct descendent of the gray wolf, Canis lupus: In other words, dogs as we know them are domesticated wolves. Not only their behavior changed; domestic dogs are different in form from wolves, mainly smaller and with shorter muzzles and smaller teeth.Darwin was wrong about dogs.he dog, Canis familiaris, is a direct descendent of the gray wolf, Canis lupus: In other words, dogs as we know them are domesticated wolves. Not only their behavior changed; domestic dogs are different in form from wolves, mainly smaller and with shorter muzzles and smaller teeth.