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After completion of an intra-luminal procedure and removal of the procedural device, a vascular closure system is used to close arteriotomy 132, as follows. As shown in FIG. 2, a guiding system including a pair of stabilization wire guides 114 is inserted into sheath 106, which may be indwelling at the end of the procedure, or inserted anew, or sheath 106 may replace a sheath that was used during the procedure.
Conversely, in neonates suffering from severe complex congenital heart defects in which an open ductus arteriosus could be beneficial, injections of prostaglandins have been used to keep the channel open. Patent ductus arteriosus. The shunt is from aorta to pulmonary artery.