Definition of sociopolitical. : of, relating to, or involving a combination of social and political factors.
Beta-1 receptors are found in the heart, and when stimulated will increase herat rate and cardiac contractility. Beta-2 receptors are found on vascular smooth muscle located in the heart and skeletal muscle, and when they are activated, they dilate and decrease SVR.
Histamine affects several receptors found in different tissues. Sometimes blocking the receptor and sometimes adding to it. Smooth muscle around bronchi in the lungs and within the intestinal tract respond to histamine stimulation by contraction, although the magnitude of response varies considerably among species. These effects also depend on which receptor is being bound by histamine; for example, the H2 receptor mediates bronchodilation.