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Effects of substituents on the acidity of phenols: Existence of electron attracting group, (for example-NO2, -X, - NR, -CN, -CHO, -COOH) on the benzene ring increases the acidity of phenol since it enables the ring to draw much more electrons from the phenoxy oxygen and so releasing easily the proton.
While there are thousands of distinct phytochemicals, most studies about the health effects of phytochemicals focus on carotenoids and polyphenols. (FYIâ¦among polyphenols, flavonoids, isoflavonid and lignans are probably the most well-known subclasses)