(IS, 4S)-4-(3, 4-dichlorophenyl)-l, .2, 3, 4- tetrahydro-N-metihyl-1-naphthalenamine, commonly known as Sertraline, is marketed in the form of its hydrochloride salt. Sertraline is used in the treatment of depression, obsessive-compulsive disorder and panic disorder.UMMARY OF THE INVENTION. The present invention discloses a novel method for the preparation of racemic sertraline starting from the known tetralone and cis(+) sertraline hydrochloride form II from cis(+) sertraline mandelate.
The mitral valve (also known as the bicuspid valve or left atrioventricular valve) is a dual-flap (bi-from the Latin, meaning double, and mitral-from the Latin, meaning shaped like a mitre) valve in the heart that lies between the left atrium (LA) and the left ventricle (LV).
mitral valve prolapse (MVP) a condition in which some portion of the mitral valve is pushed back into the left atrium during ventricular contraction.For reasons not fully understood (there is no evident disease process) there is redundant tissue on one or both leaflets of the valve.itral valve prolapse. n. Abbr. MVP. A condition in which there is excessive retrograde movement of the mitral valve into the left atrium during left ventricular systole, often allowing mitral regurgitation.