1 To establish the maximum tolerable dose of betahistine dihydrochloride (betahistine) within the range of 50 mg to 300 mg/day that appears to be effective for atypical depression. Are at significant risk of suicide as indicated by a score of 3 or greater on item number 11 on the HAM-D 28. 2  Have received any investigational product within 28 days of Screening. 3  Have used any antidepressant within 7 days of Screening (14 days for MAOIs; 21 days for fluoxetine).
Boulder Creek, California. Boulder Creek is a census-designated place (CDP) in Santa Cruz County, California, with a population of 4,923 as of the 2010 census.
Riverbank is a city in Stanislaus County, California, United States. The population was 22,678 at the 2010 census, up from 15,826 at the 2000 census. It is part of the Modesto Metropolitan Statistical Area.