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Muscle spasms and cramps. Cramps are caused by muscle spasms, involuntary contractions of one or more muscles. In addition to the foot and calf muscles, other muscles prone to spasms include the front and back of the thigh, the hands, arms, abdomen and muscles along the ribcage.uscle cramps can have many possible causes. They include: 1  Poor blood circulation in the legs. 2  Overexertion of the calf muscles while exercising. 3  Insufficient stretching before exercise.
Muscle twitches, also called fasciculations, usually only affect a single muscle. They're characterized by tiny contractions inside the muscle, caused by a nerve impulse. Muscle spasms, also called muscle cramps, affect multiple muscle tissues and are brought on by a chemical imbalance in the body.isorders of the nervous system can also cause muscles to twitch. These include nerve damage, fibromyalgia, muscular dystrophy and Lou Gehrig's disease. Along with muscle twitching, weakness in the muscles accompanies these disorders.