Definition of sociopolitical. : of, relating to, or involving a combination of social and political factors.
Beta-1 receptors are found in the heart, and when stimulated will increase herat rate and cardiac contractility. Beta-2 receptors are found on vascular smooth muscle located in the heart and skeletal muscle, and when they are activated, they dilate and decrease SVR.
Fibroblast growth factors (fgfs) are widely believed to activate their receptors by mediating receptor dimerization. Here we show, however, that the FGF receptors form dimers in the absence of ligand, and that these unliganded dimers are phosphorylated. We further show that ligand binding triggers structural changes in the FGFR dimers, which increase FGFR phosphorylation.