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It is named after John Langdon Down, the British doctor who fully described the syndrome in 1866. Some aspects of the condition were described earlier by Jean-Ãtienne Dominique Esquirol in 1838 and Ãdouard SÃ©guin in 1844. In 1957, the genetic cause of Down syndrome, an extra copy of chromosome 21, was discovered.
Sir John Franklin. Sir John Franklin was a famous British explorer who went to the Arctic in search of the North-West Passage, dying on his last attempt in 1847. John Franklinâs early North-West Passage expeditions 1819â27. Sir John Franklin is one of the famous explorers who went in search of the North-West Passage.