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It is named after John Langdon Down, the British doctor who fully described the syndrome in 1866. Some aspects of the condition were described earlier by Jean-Ãtienne Dominique Esquirol in 1838 and Ãdouard SÃ©guin in 1844. In 1957, the genetic cause of Down syndrome, an extra copy of chromosome 21, was discovered.
Eddie BauerâVerified account @eddiebauer Apr 13. Eddie Bauer Retweeted Costume Society UK. Eddie actually invented the first quilted down jacket in 1936; in 1940, it became the first patented down jacket in America. #themoreyouknowhttps://twitter.com/costume_society/status/814810780973473792 â¦.