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Numb Big Toe. Numbness in the toes is can be caused by from nerve damage due to disease, but more commonly certain biomechanical conditions can put pressure on the nerves on the side of the foot and lead to numbness of the big toe. If the issue is physical stress, it can be easily remedied to restore sensation.
Gout, a form of acute arthritis, most commonly occurs in the big toe. It is caused by high levels of uric acid in the blood, in which urate crystals settle in the tissues of the joints and produce severe pain and swelling. to take a sample of fluid from the joint and test it for urate crystals.