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A lupus flare up is a temporary worsening of the symptoms that are related to the disease. When a SLE flare is imminent, there may be certain ways to tell. Patients with lupus may notice changes in their body before the flare actually occurs. They may notice subtle changes in their symptoms, or new symptoms could occur.
Any trigger that creates an inflammatory response can/will cause a flare up - especially if you are not on maintenance medications. For some patients - even ones in remission, triggers such as GI infection, systemic illness, significant change in diet and activity, or severe emotional stress can result in a flare up.