Van Pelt in Jumanji: The Animated Series. Van Pelt returns as a recurring villain in the animated series based on the movie. He is revealed to be a part of the game, and when he actually dies in an episode, Peter starts to become him little by little, but is saved by Alan and Judy.
http://www.chacha.com/question/which-episode-of-grey's-anatomy-does-izzy-get-diagnosed-with-cancer. Izzie discovers she has metastatic melanoma (Stage IV) in season 5 episode 17 I Will Follow You Into the Dark of Grey's Anatomy.
When Isaac, the hospital lab tech, has an inoperable tumor wrapped around his spine, he turns to Dr. Derek Shepherd to do the impossible, and Derek tests the Chief's authority when Richard objects to moving forward with the risky surgery.