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Irritant contact dermatitis. Irritant contact dermatitis occurs when your skin comes into direct contact with a substance that damages the outer layer of your skin, causing redness, itching, and a burning or stinging sensation.
A common cause of severe itching is allergic reaction. Contact dermatitis is caused by irritants such as detergents, soaps, fabrics or chemicals. A physician can recommend the appropriate topical or oral preparation for this condition. Medications such as antibiotics can cause itching as well.