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Best Answer: There is only a .2% change in the DNA of all breeds and that change is all in appearance... Anyway, the three breeds that are the closest to a wolf have to be a German Shepherd, Husky, and an Alaskan Malamute... Source(s): Capt. Jack Sparrow Â· 6 years ago.
1. The species Canis lupus covers a lot of dogs. There are 39 subspecies, one of them being all domestic dog breeds. Thirty-seven of these subspecies are wolves, the largest and most common being the Eurasian gray wolf (Canis lupus lupus), the common ancestor of domestic dog breeds.The gray wolf is found throughout the Northern Hemisphere and comes in black, brown, grey, and white, or a combination of these colors.hirty-seven of these subspecies are wolves, the largest and most common being the Eurasian gray wolf (Canis lupus lupus), the common ancestor of domestic dog breeds. The gray wolf is found throughout the Northern Hemisphere and comes in black, brown, grey, and white, or a combination of these colors.