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A lupus flare up is a temporary worsening of the symptoms that are related to the disease. When a SLE flare is imminent, there may be certain ways to tell. Patients with lupus may notice changes in their body before the flare actually occurs. They may notice subtle changes in their symptoms, or new symptoms could occur.
1 Drug-induced lupus is a form of lupus caused by certain medicines. 2  The symptoms of drug-induced lupus are like those of systemic lupus, but only rarely affect major organs. 3  Symptoms can include joint pain, muscle pain, and fever, and are mild for most people. Common symptoms include fatigue, hair loss, sensitivity to the sun (photosensitivity), painful and swollen joints, unexplained fever, skin rashes, and kidney problems. 2  In general the diagnosis of lupus is based off of a combination of physical symptoms and laboratory results.