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(January 2013). Gonadotropin-releasing hormone (GnRH), also known as luteinizing hormone-releasing hormone (LHRH) and luliberin, as well as gonadorelin (INN), is a trophic peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary.January 2013). Gonadotropin-releasing hormone (GnRH), also known as luteinizing hormone-releasing hormone (LHRH) and luliberin, as well as gonadorelin (INN), is a trophic peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary.
FSH stimulates the maturation of germ cells within the testes and ovaries. In the female it also stimulates follicular development and oestradiol synthesis. In the male FSH also stimulates the secretion of inhibin which has a negative feedback directly to the anterior pituitary.SH is a type of glycoprotein that is produced in the anterior pituitary via gonadotroph cells. FSH secretion is regulated by GnRH from the hypothalamus. The target tissue of FSH in males are the sertoli cells within the testes and in the female the granulosa cells of the ovary.