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A lupus flare up is a temporary worsening of the symptoms that are related to the disease. When a SLE flare is imminent, there may be certain ways to tell. Patients with lupus may notice changes in their body before the flare actually occurs. They may notice subtle changes in their symptoms, or new symptoms could occur.
Fatigue: Lupus causes mild to extreme fatigue. Even mild cases of lupus make it hard to do daily activities and exercise. Increased fatigue is a classic sign that a symptom flare is about to occur. Joint and muscle pain: Joints may be painful, red, and warm. They may swell. Morning stiffness may also be felt.