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Congenital disorder, also known as congenital disease, birth defect or anomaly, is a condition existing at or before birth regardless of cause. Of these diseases, those characterized by structural deformities are termed congenital anomalies and involve defects in a developing fetus. Birth defects vary widely in cause and symptoms. Any substance that causes birth defects is known as a teratogen.
Children who have genetic disorders, such as Down syndrome, often have congenital heart defects. In fact, half of all babies who have Down syndrome have congenital heart defects. Smoking during pregnancy also has been linked to several congenital heart defects, including septal defects. Researchers continue to search for the causes of congenital heart defects.