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Born Alessandro di Mariano Filipepi in Florence in 1445, Botticelli was apprenticed to a goldsmith. Later he was a pupil of the painter Fra Filippo Lippi. He spent all his life in Florence except for a visit to Rome in 1481-82. There he painted wall frescoes in the Sistine Chapel of the Vatican. In Florence, Botticelli was a protege of several members of the powerful Medici family.
There is also one Florentine painter who shows much of Masaccio's interest in modeling and space, Giovanni Toscani, and it is conceivable that Masaccio was one of his pupils. Other possible masters to Masaccio were Bicci di Lorenzo and Francesco di Antonio.