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Alcohol poisoning is a serious â and sometimes deadly â consequence of drinking large amounts of alcohol in a short period of time. Drinking too much too quickly can affect your breathing, heart rate, body temperature and gag reflex and potentially lead to a coma and death.
However, in overdose, local damage to the GI mucosa allows unregulated absorption, which leads to potentially toxic serum levels. Much of the pathophysiology of iron poisoning is a result of metabolic acidosis and its effect on multiple organ systems. Toxicity manifests as local and systemic effects.