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Best Answer: There is only a .2% change in the DNA of all breeds and that change is all in appearance... Anyway, the three breeds that are the closest to a wolf have to be a German Shepherd, Husky, and an Alaskan Malamute... Source(s): Capt. Jack Sparrow Â· 6 years ago.
The grey wolf (Canis lupus), or just wolf, is a mammal of the order Carnivora, and the ancestor of the domestic dog. It is sometimes called timber wolf. A recent study found that the domestic dog is descended from wolves tamed less than 16,300 years ago south of the Yangtze River in China. There are many different wolf subspecies, such as the Arctic wolf.