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A lupus flare up is a temporary worsening of the symptoms that are related to the disease. When a SLE flare is imminent, there may be certain ways to tell. Patients with lupus may notice changes in their body before the flare actually occurs. They may notice subtle changes in their symptoms, or new symptoms could occur.
About 1 in 10 people with discoid lupus eventually develop systemic lupus, and about 3 in 10 people with systemic lupus have discoid lupus rashes. Drug-induced lupus can develop with certain medicines. In a very small number of people, certain prescription medicines lead to the development of S.L.E. symptoms.