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Best Answer: There is only a .2% change in the DNA of all breeds and that change is all in appearance... Anyway, the three breeds that are the closest to a wolf have to be a German Shepherd, Husky, and an Alaskan Malamute... Source(s): Capt. Jack Sparrow Â· 6 years ago.
Taxonomy and Species of Wolf. Wolves are part of the canine family, also known as Canidae. Within the Canidae, seven species are termed 'wolf', of which only four are considered 'true' wolves. The most threatened wolf species include the Red wolf and Ethiopian wolf. - the Grey Wolf (Canis lupus), - the Red Wolf (Canis rufus),