Paul Walker has topped the Google UK Zeitgeist chart of the most searched for people on the internet in 2013. The late Fast & Furious star, who died in a car crash on 30 November, was laid to rest during a funeral on Sunday.
Understanding First Pass Metabolism. The drug is absorbed from the GI tract and passes via the portal vein into the liver where some drugs are metabolised. Sometimes the result of first pass metabolism means that only a proportion of the drug reaches the circulation. First pass metabolism can occur in the gut and the liver. For example, first pass metabolism occurs in the gut for benzylpenicillin and insulin and in the liver for propranolol, lignocane, chloromethiasole and GTN.
Probably not. There is such a thing as a slow metabolism. But slow metabolism is rare, and it's usually not what's behind being overweight or obese â that's ultimately a result of interactions among genetics, diet, physical activity and other factors. Metabolism is the process by which your body converts what you eat and drink into energy. Even when you're at rest, your body needs energy for functions such as breathing, circulating blood and repairing cells. The number of calories your body uses for these basic functions is known as your basal metabolic rate.