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DEFICIENCY SYMPTOMS: Symptoms and signs of lysine deficiency include: anemia, apathy, bloodshot eyes, depression, edema, fatigue, fever blisters, hair loss, inability to concentrate, infertility, irritability, lethargy, liver damage, loss of energy, muscle loss, retarded growth, stomach ulcers, and weakness.
1 Canker sores. 2  Early research suggests that taking 500 mg of lysine daily prevents canker sores and 4000 mg daily decreases the length of canker sores. 3  Diabetes. 4  Some evidence shows that taking lysine daily for 2 months does not affect blood sugar levels in people with diabetes.