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Born Alessandro di Mariano Filipepi in Florence in 1445, Botticelli was apprenticed to a goldsmith. Later he was a pupil of the painter Fra Filippo Lippi. He spent all his life in Florence except for a visit to Rome in 1481-82. There he painted wall frescoes in the Sistine Chapel of the Vatican. In Florence, Botticelli was a protege of several members of the powerful Medici family.
Born out of wedlock to a notary, Piero da Vinci, and a peasant woman, Caterina, in Vinci in the region of Florence, Leonardo was educated in the studio of the renowned Florentine painter Andrea del Verrocchio.Much of his earlier working life was spent in the service of Ludovico il Moro in Milan.n 1482 Leonardo, who according to Vasari was a most talented musician, created a silver lyre in the shape of a horse's head. Lorenzo de' Medici sent Leonardo to Milan, bearing the lyre as a gift, to secure peace with Ludovico Sforza, Duke of Milan.