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A lupus flare up is a temporary worsening of the symptoms that are related to the disease. When a SLE flare is imminent, there may be certain ways to tell. Patients with lupus may notice changes in their body before the flare actually occurs. They may notice subtle changes in their symptoms, or new symptoms could occur.
Easing Joint and Muscle Pain. For many people, joint pain and stiffness are the first symptoms of lupus, or a sign that a flare is coming on. Joints in the hands, wrists and feet get stiff and painful to move, sometimes so much so that it is hard to get up from a chair or button a shirt.or many people, joint pain and stiffness are the first symptoms of lupus, or a sign that a flare is coming on. Joints in the hands, wrists and feet get stiff and painful to move, sometimes so much so that it is hard to get up from a chair or button a shirt.