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Q: How often do doctors give cortisone injections to a patient? A: We try to limit the injection to one every three months for any single joint, but also we like to limit it to a total of six injections a year for the whole body. We know that the cortisone can sometimes weaken or suppress the immune system and, in diabetics, it raises blood sugar.
The cortisone starts working in about 5 to 7 days and its effect can last for several days to many months. How many injections do I need to have? If the ï¬rst injection does not relieve your symptoms in about a week to two weeks, you may be recommended to have one more injection.he cortisone starts working in about 5 to 7 days and its effect can last for several days to many months. How many injections do I need to have? If the ï¬rst injection does not relieve your symptoms in about a week to two weeks, you may be recommended to have one more injection.