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Addisonâs disease most commonly affects female dogs around four or five years old. This condition is typically caused by injury to the adrenal glandsâ tissue from infection, hemorrhaging, or autoimmune disorders. If your pet is coming off of steroid treatment, the steroid withdrawal may also be causing an imbalance.
In dogs, diabetes mellitus is caused by the failure of the pancreas to produce enough insulin to regulate blood sugar. This is Insulin Dependent Diabetes Mellitus (also called Type 1 Diabetes). This type of diabetes usually results from destruction of most or all of the beta-cells that produce insulin in the pancreas. As the name implies, dogs with this type of diabetes require insulin injections to stabilize blood sugar levels.