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Best Answer: There is only a .2% change in the DNA of all breeds and that change is all in appearance... Anyway, the three breeds that are the closest to a wolf have to be a German Shepherd, Husky, and an Alaskan Malamute... Source(s): Capt. Jack Sparrow Â· 6 years ago.
Extraordinary images that show just how similar we are to our closest living relative â the bonobo: Affectionate primates share 98.7% of human DNA right down to hair loss. Species is usually found in the Congo, but they are classed as endangered due to conflict and other atrocities