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Rating Newest Oldest. Best Answer: the most active place for absorption is jejunum. it's not the colon of course because it's part of large intestin and not stomach because it's digestive part and not absorptive. although duodenum is also part of small intestin but duodenum and jejunum have differant anatomy.
It also occurs in the liver, when it produces bile to break down fat, and the liver also breaks down medicine, and small intestine, the small intestine is where the main chemical digestion occurs, the small intestine absorbs all the nutrients into the blood streams.+ 36 others found this useful.Marcus Haldane.hemical digestion occurs int he stomach where acids break down the food turning it into chyme, and also happens in the mouth where saliva mixed with enzymes break food into b â¦ olus.