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Best Answer: There is only a .2% change in the DNA of all breeds and that change is all in appearance... Anyway, the three breeds that are the closest to a wolf have to be a German Shepherd, Husky, and an Alaskan Malamute... Source(s): Capt. Jack Sparrow Â· 6 years ago.
Wolf Hybrid. Wolf / Domestic Dog Cross. As of about 1990 the correct term for a mix of a wolf and a domestic dog is âwolfdog.â The dog was reclassified as a sub-species of wolf (canis lupus familiaris) and as such, it is impossible to have a hybrid as they are two of the same species.t is a cross between a domestic dog and a wolf. The best way to determine the temperament of a mixed breed is to look up all breeds in the cross and know you can get any combination of any of the characteristics found in either breed.