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Acetyl coenzyme A or acetyl-CoA is an important molecule in metabolism, used in many biochemical reactions.Its main function is to convey the carbon atoms within the acetyl group to the citric acid cycle (Krebs cycle) to be oxidized for energy production.he oxidative conversion of pyruvate into acetyl-CoA is referred to as the pyruvate dehydrogenase reaction. It is catalyzed by the pyruvate dehydrogenase complex. Other conversions between pyruvate and acetyl-CoA are possible.
Introduction: Under aerobic conditions the end product of glycolysis is pyruvic acid. The next step is the formation of acetyl coenzyme A (acetyl CoA) - this step is technically not a part of the citric acid cycle, but is shown on the diagram on the top left.Acetyl CoA, whether from glycolysis or the fatty acid spiral, is the initiator of the citric acid cycle.he initiating step of the citric acid cycle occurs when a four carbon compound (oxaloacetic acid) condenses with acetyl CoA (2 carbons) to form citric acid (6 carbons). The whole purpose of a turn of the citric acid cycle is to produce two carbon dioxide molecules.