This is not a direct indication as to how commonly these diseases are the actual cause of Rheumatoid factor positive, but gives a relative idea as to how frequent these diseases are seen overall. 1  3 diseases that are common. 2  2 diseases that are very rare. 3  8 diseases without any prevalence information. Causes of Rheumatoid factor positive that are common The following causes of Rheumatoid factor positive are diseases or conditions that affect more than 1 million people in the USA: Connective tissue diseases.
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