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Best Answer: There is only a .2% change in the DNA of all breeds and that change is all in appearance... Anyway, the three breeds that are the closest to a wolf have to be a German Shepherd, Husky, and an Alaskan Malamute... Source(s): Capt. Jack Sparrow Â· 6 years ago.
The Borzoi (/ËbÉrzÉÉª/ , literally fast), also called the Russian wolfhound (Russian: ÑÑÌÑÑÐºÐ°Ñ Ð¿ÑÐ¾Ð²Ð°Ñ Ð±Ð¾ÑÐ·Ð°Ñ), is a breed of domestic dog (Canis lupus familiaris). Descended from dogs brought to Russia from central Asian countries, it is similar in shape to a greyhound, and is also a member of the sighthound family.