Home >> Signaling Pathways >> GPCR/G protein >> Somatostatin Receptor Somatostatin Receptor Somatostatin receptor is a G protein-coupled receptor that includes five known somatostatin receptors.
Drugs Causing Lowering of Sodium Level or Hyponatremia. Drugs are one of the causes implicated in the development of lowering of sodium level or hyponatremia. Diuretics: Thiazides, bumetanide, indapamide, ethacrynic acid, furosemide. Diuretics affect the balance between sodium and water and are among the most common drugs implicated in the development of hyponatremia. Antidepressants: Selective serotonin reuptake inhibitors, tricyclic antidepressants (amitriptyline, protriptyline, desipramine), monoamine oxidase inhibitors, venlafaxine.
Too little water may lead to high sodium levels in the blood. The Merck Manual characterizes a high sodium level, or hypernatremia, as too much sodium in the body in relation to the amount of water. Sodium is found in the blood and the fluid around the cells and is regulated by the kidneys.