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Cortisol- the major glucocorticoid produced in humans, which is commonly known as the stress hormone 9. Hans Selye- proposed a three-stage model to describe the changes in physiology that occurs during exposure to severe stressors.
Consultation with Medical Advisory should be considered. 1  Experiencing a severe stressor * before the clinical onset, or clinical worsening, of Posttraumatic Stress Disorder. * 2  A severe stressor is a direct personal experience of an event that involves actual or threatened death or serious injury, or other threat to one's physical integrity; or ...efinition. Posttraumatic Stress Disorder (PTSD) is characterized by the onset of psychiatric symptoms after exposure to a traumatic event.