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Parkinson's diseaseback to top. As Parkinson's disease progresses, it often results in a progressive dementia similar to dementia with Lewy bodies or Alzheimer's. Symptoms: Problems with movement are common symptoms of the disease. If dementia develops, symptoms are often similar to dementia with Lewy bodies. Brain changes: Alpha-synuclein clumps are likely to begin in an area deep in the brain called the substantia nigra.
Early LBD symptoms are often confused with similar symptoms found in other brain diseases like Alzheimerâs. Also, LBD can occur alone or along with Alzheimerâs or Parkinsonâs disease. There are two types of LBD â dementia with Lewy bodies and Parkinsonâs disease dementia. The earliest signs of these two diseases differ but reflect the same biological changes in the brain.