Pay the fee. As of April 2015, an adult renewal is $110. If you need you passport fast and wish to have it expedited, it will cost an extra $60. If you have to file a DS-11 rather than a DS-82, you will also have to pay a $25 acceptance fee.
Over the past 25 years, a new class of drugs has become available to boost marrow function: the hematopoietic growth factors (HGFs).
The primary role of TNF is in the regulation of immune cells. TNF, being an endogenous pyrogen, is able to induce fever, apoptotic cell death, cachexia, inflammation and to inhibit tumorigenesis and viral replication and respond to sepsis via IL1 & IL6 producing cells.