Deletion. (Science: genetics) a chromosome abnormality in which part of a single chromosome has been lost. Please contribute to this project, if you have more information about this term feel free to edit this page. This page was last modified on 3 October 2005, at 21:16.This page has been accessed 49,284 times. What links here | Related changes | Permanent link.
A decade earlier, only 13 therapies were recognized as orphan treatments. Worldwide sales of orphan drugs amounted to less than $20 billion in 2000, but by 2020 are forecast to cost $176 billion, according to EvaluatePharma, a market research firm. By that year, the money spent on orphan drugs will account for about 19 percent of the worldâs total drug expense. Orphan drugs treat diseases that affect fewer than 200,000 people in the United States and cost an average of $137,000 a year. And treatments for so-called ultra-rare diseases, like the disorder that Synageva targets, generally cost much more.
Information on applications for orphan drug status can be found in the Applications for orphan drug designation. The quality, efficacy and safety of orphan drugs are assessed at the same standard as for other registered medicines.Drugs designated as orphan drugs by the TGA are shown in the table below.esignated orphan drugs are eligible for a waiver of their application and evaluation fees, but only if designation is received prior to submitting an application to register an orphan drug on the Australian Register of Therapeutic Goods (ARTG) .