Pay the fee. As of April 2015, an adult renewal is $110. If you need you passport fast and wish to have it expedited, it will cost an extra $60. If you have to file a DS-11 rather than a DS-82, you will also have to pay a $25 acceptance fee.
Over the past 25 years, a new class of drugs has become available to boost marrow function: the hematopoietic growth factors (HGFs).
Thrombopoietin (THPO) also known as megakaryocyte growth and development factor (MGDF) is a protein that in humans is encoded by the THPO gene. Thrombopoietin is a glycoprotein hormone produced by the liver and kidney which regulates the production of platelets. It stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets.