Alport syndrome or hereditary nephritis is a genetic disorder characterized by glomerulonephritis, end-stage kidney disease, and hearing loss. Alport syndrome can also affect the eyes, causing eye abnormalities including cataracts, lenticonus, kerataconus, as well as retinal flecks in the macula and mid-periphery.utations in any of these genes prevent the proper production or assembly of the type IV collagen network, which is an important structural component of basement membranes in the kidney, inner ear, and eye. Basement membranes are thin, sheet-like structures that separate and support cells in many tissues.
A corporate portfolio analysis may determine a company's future direction. Comstock/Comstock/Getty Images. A corporate portfolio analysis takes a close look at a companyâs services and products.Each segment of a companyâs product line is evaluated including sales, market share, cost of production and potential market strength. The analysis categorizes the companyâs products and looks at the competition. corporate portfolio analysis may determine a company's future direction. Comstock/Comstock/Getty Images. A corporate portfolio analysis takes a close look at a companyâs services and products.
1 Portfolio theory: A strategy based primarily on diversification through acquisition. 2  The corporation shifts resources among the units and monitors the performance of each business unit and its leaders. 3  Each unit generally runs autonomously, with limited interference from the corporate center provided goals are met.