As more and more people move into cities and towns, a number of factors cause pollution: 1  the physical disturbance of land due to construction of houses, industries, roads, etc.; 2  chemical pollution from industries, mines, etc.; 3  inadequate sewage collection and treatment; 4  increase in fertilisers to grow more food. 5  litter, which causes disease and ...
In the knee joint, operations to exchange the original implant (prosthesis) with a new one have a good chance of success. The decision to do a revision surgery depends in part on the type of bacteria that has infected the joint. In some uncommon cases, the type of bacteria is so harmful that a revision is not possible.
In the clinical trials, amputations of the toe and mid-foot occurred most frequently; however, amputations involving the leg, below and above the knee, also occurred. Lower limb infections, gangrene, diabetic foot ulcers, and ischemia were the most common precipitating medical events leading to the need for an amputation.