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Cirrhosis: Vasoconstrictor Medicines for Variceal Bleeding. Cirrhosis: Vasoconstrictor Medicines for Variceal Bleeding. Medicines that constrict small blood vessels and reduce blood flow to the portal vein are used to treat sudden (acute) bleeding from enlarged veins (varices) in the digestive tract (variceal bleeding). Octreotide is the main medicine used in the United States to treat variceal bleeding.
A: Peripheral vasoconstriction is the constriction of peripheral blood vessels. When constriction of blood vessels occurs, the diameter of the blood vessel decreases, causing a decrease in blood flow. Peripheral blood vessels are those blood vessels which do not supply blood to major organs or skeletal muscles. A good example of the function of peripheral blood vessels is the blood supply to the skin. Peripheral vasoconstriction, and its opposite, vasodilation, are key to the way in which the human body regulates temperature.