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Cirrhosis: Vasoconstrictor Medicines for Variceal Bleeding. Cirrhosis: Vasoconstrictor Medicines for Variceal Bleeding. Medicines that constrict small blood vessels and reduce blood flow to the portal vein are used to treat sudden (acute) bleeding from enlarged veins (varices) in the digestive tract (variceal bleeding). Octreotide is the main medicine used in the United States to treat variceal bleeding.
Vasoconstriction. 1  There are muscles around all the major arteries of our body that automatically constrict or relax in order to decrease or increase blood flow. This allows the body to send more blood and warmth to the critical organs of your body (like the heart, lungs and brain), temporarily decreasing the blood flow to your hands and feet. Cold hand diseases that occur from vasoconstriction happen when these muscles apply pressure to the arteries for too long, which decreases blood flow.