Alport syndrome or hereditary nephritis is a genetic disorder characterized by glomerulonephritis, end-stage kidney disease, and hearing loss. Alport syndrome can also affect the eyes, causing eye abnormalities including cataracts, lenticonus, kerataconus, as well as retinal flecks in the macula and mid-periphery.utations in any of these genes prevent the proper production or assembly of the type IV collagen network, which is an important structural component of basement membranes in the kidney, inner ear, and eye. Basement membranes are thin, sheet-like structures that separate and support cells in many tissues.
A corporate portfolio analysis may determine a company's future direction. Comstock/Comstock/Getty Images. A corporate portfolio analysis takes a close look at a companyâs services and products.Each segment of a companyâs product line is evaluated including sales, market share, cost of production and potential market strength. The analysis categorizes the companyâs products and looks at the competition. corporate portfolio analysis may determine a company's future direction. Comstock/Comstock/Getty Images. A corporate portfolio analysis takes a close look at a companyâs services and products.
Once the general expectation of performance in an industry is understood, it is possible to compare that expectation with the company's current level of performance. This comparison becomes the gap analysis. Such analysis can be performed at the strategic or at the operational level of an organization. Gap analysis is a formal study of what a business is doing currently and where it wants to go in the future. It can be conducted, in different perspectives, as follows: Organization (e.g., Human Resources) Business direction.