Alport syndrome or hereditary nephritis is a genetic disorder characterized by glomerulonephritis, end-stage kidney disease, and hearing loss. Alport syndrome can also affect the eyes, causing eye abnormalities including cataracts, lenticonus, kerataconus, as well as retinal flecks in the macula and mid-periphery.utations in any of these genes prevent the proper production or assembly of the type IV collagen network, which is an important structural component of basement membranes in the kidney, inner ear, and eye. Basement membranes are thin, sheet-like structures that separate and support cells in many tissues.
A corporate portfolio analysis may determine a company's future direction. Comstock/Comstock/Getty Images. A corporate portfolio analysis takes a close look at a companyâs services and products.Each segment of a companyâs product line is evaluated including sales, market share, cost of production and potential market strength. The analysis categorizes the companyâs products and looks at the competition. corporate portfolio analysis may determine a company's future direction. Comstock/Comstock/Getty Images. A corporate portfolio analysis takes a close look at a companyâs services and products.
This environmental analysis is a three-step process in which a company first identifies environmental factors that affect its business. For example, the company might consider if a market is âdifficultâ because of its remote geographic location or the area's unfavorable economic conditions.The company then gathers information about the selected set of environmental factors that are most likely to impact business operations.his analysis identifies the opportunities and threats in a business environment in terms of a company's strengths and weaknesses. For example, a company may consider the impact of operating in a communist country and the threats posed by government-controlled resources.