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When itâs time to spay your dog. She can be spayed any time after eight weeks of age, and preferably before her first heat for the best health benefits. The first heat cycle occurs somewhere around six months of age, depending on the breed.he benefits to your dog are considerable: 1  Spaying reduces risk of certain illnesses, such as pyometra (a common, life-threatening infection of the uterus) or mammary gland cancer. 2  Spaying reduces pet overpopulation. 3  Millions of dogs are put down every year because there arenât enough homes for them.
The average female dog has her first cycle about six months of age. A few dogs start earlier and few dogs later, even as late as 14-months. If you have a new female puppy, you should watch her and note when she has her first cycle. If shes 14-months old and still hasnt been in heat, you should take her to a veterinarian. 4.