Pay the fee. As of April 2015, an adult renewal is $110. If you need you passport fast and wish to have it expedited, it will cost an extra $60. If you have to file a DS-11 rather than a DS-82, you will also have to pay a $25 acceptance fee.
Over the past 25 years, a new class of drugs has become available to boost marrow function: the hematopoietic growth factors (HGFs).
However, the liver and the bone marrow stromal cells are the primary sites of thrombopoietin production. Thrombopoietin regulates the differentiation of megakaryocytes and platelets, but studies on the removal of the thrombopoietin receptor show that its effects on hematopoiesis are more versatile.