The theoretical model builds on the concept of continental drift developed during the first few decades of the 20th century. The geoscientific community accepted plate-tectonic theory after seafloor spreading was validated in the late 1950s and early 1960s. The lithosphere, which is the rigid outermost shell of a planet (the crust and upper mantle), is broken up into tectonic plates.
These disorders are known as monogenetic disorders (disorders of a single gene). Some examples of monogenetic disorders include: 1  cystic fibrosis, 2  sickle cell anemia,3  Marfan syndrome, 4  Huntington's disease, and.5  hemochromatosis.ome examples of monogenetic disorders include: 1  cystic fibrosis, 2  sickle cell anemia, 3  Marfan syndrome, 4  Huntington's disease, and. 5  hemochromatosis.
Examples include: 1  Infectious diseases, such as AIDS, viral hepatitis, tuberculosis, and typhoid fever. 2  Autoimmune disorders, such as lupus. 3  Steroid therapy. 4  Blood cancer and other blood diseases, such as Hodgkin's disease and aplastic anemia. 5  Radiation and chemotherapy (treatments for cancer).