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It has been recognized for over 50 years that combined oral contraceptives (COCs) are also capable of offering health benefits beyond contraception through the treatment and prevention of several gynaecological and medical disorders.
The advantages of nasal delivery include. (1) lower doses, (2) rapid local therapeutic. effect, (3) rapid systemic therapeutic blood levels, (4) rapid onset of pharmacological activity, and (5) relatively few side effects. ln addition to the nasal. decongestants, saline and other routine locally actÂ­.