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Cortisol- the major glucocorticoid produced in humans, which is commonly known as the stress hormone 9. Hans Selye- proposed a three-stage model to describe the changes in physiology that occurs during exposure to severe stressors.
Stress is thought to be an important factor in many health problems. Early stress researchers found that regardless of the environmental stressor, a generalized physiological response was activated in the organism called the fight or flight, or stress response and termed the General Adaptation Syndrome by Hans Selye.