Another related concept is that neoadjuvant therapy acts on micrometastatic disease. The downstaging is then a surrogate marker of efficacy on undetected dissemination, resulting in improved longtime survival compared to the surgery-alone strategy.
Mexican-American Cesar Chavez (1927-1993) was a prominent union leader and labor organizer. Hardened by his early experience as a migrant worker, Chavez founded the National Farm Workers Association in 1962. His union joined with the Agricultural Workers Organizing Committee in its first strike against grape growers in California, and the two organizations later merged to become the United Farm Workers.
During this time, Dolores met Cesar Chavez, a fellow CSO official, who had become its director. In 1962, both Huerta and Chavez lobbied to have the CSO expand its efforts to help farm workers, but the organization was focused on urban issues and couldnât move in that direction.