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Cirrhosis: Vasoconstrictor Medicines for Variceal Bleeding. Cirrhosis: Vasoconstrictor Medicines for Variceal Bleeding. Medicines that constrict small blood vessels and reduce blood flow to the portal vein are used to treat sudden (acute) bleeding from enlarged veins (varices) in the digestive tract (variceal bleeding). Octreotide is the main medicine used in the United States to treat variceal bleeding.
vasoconstriction Active narrowing of small arteries as a result of contraction of the circular smooth muscle fibres in their walls. This severely reduces the flow of blood through them. Compare VASODILATATION. vasoconstriction