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The biggest cause, however, for the throat lump, and for the sensation that something is stuck there, is ANXIETY â including anxiety over bulbar-onset ALS. Anxiety begets the lumpy feeling in the throat. This is why, in many novels, for example, a character whoâs nervous is described as feeling âa lump in her throat.â.
Several conditions can cause a sore throat. Sore throats may be caused by a viral illness, such as: 1  The common cold, the most common type of viral infection. 2  Infection of the voice box (laryngitis).3  Mononucleosis (mono, the kissing disease), a viral infection that tends to cause a persistent sore throat.everal conditions can cause a sore throat. Sore throats may be caused by a viral illness, such as: 1  The common cold, the most common type of viral infection. 2  Infection of the voice box (laryngitis).