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The reduction in the rate of systolic ejection following elevation of aortic pressure leads to changes in cardiac output opposite to alteration in peripheral resistance, thus tending to maintain a relatively constant arterial pressure.
What is Blood doping effect on blood flow? A large infusion of red blood cells (and resulting increase in cellular concentration) could increase blood viscosity and bring about a decrease in cardiac output, a decrease â¦in blood flow velocity, and a reduction in peripheral oxygen content - all of which would reduce aerobic capacity (#7).