Erythropoiesis = formation of erythrocytes. 1  the body must produce about 2.5 million new RBCs every second. 2  in adults, erythropoiesis occurs mainly in the marrow of the sternum, ribs, vertebral processes, and skull bones. 3  begins with a cell called a hemocytoblast or stem cell (below)  rate is regulated by oxygen levels:
1 Second Intention Healing â A wound that is extensive and involves considerable tissue loss, and in which the edges cannot be brought together heals in this manner. 2  This is how pressure ulcers heal. 3  Secondary intention healing differs from primary intention healing in three ways:
When body tissue is damaged by trauma, surgery, hypoxia, or other destructive processes, it quickly reacts to protect itself and begin the process of healing. Clean surgical wounds closed by primary intention heal rapidly and do not usually require additional medical intervention and support. Chronic wounds and those left to heal by secondary intention will require more attention from the medical team.