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Certain medications may also lead to a low white blood cell count because they can destroy white blood cells or damage the bone marrow. For example, taking antibiotics may sometimes cause an abnormal drop in neutrophils, a condition known as neutropenia.
A low white blood cell count, or leukopenia, is a decrease in disease-fighting cells (leukocytes) circulating in your blood. The threshold for a low white blood cell count varies from one medical practice to another.Some healthy people have white cell counts that are lower than what's considered normal.A count lower than 4,000 white blood cells per microliter of blood is generally considered a low white blood cell count. The threshold for a low white blood cell count in children varies with age and sex.1  Causes. low white blood cell count, or leukopenia, is a decrease in disease-fighting cells (leukocytes) circulating in your blood. The threshold for a low white blood cell count varies from one medical practice to another.