In bacteria, transcription begins with the binding of RNA polymerase to the promoter in DNA. RNA polymerase is a core enzyme consisting of five subunits: 2 Î± subunits, 1 Î² subunit, 1 Î²' subunit, and 1 Ï subunit.
Untreated gout can cause a risk for diabetes and heart disease. Chronic gout can also cause kidney stones. Gout is caused by a buildup of uric acid in the blood. It cristalizes in the joints, with the big toe being the location in half of the cases. This is called podagra.
Gout Due To Kidney Failure. Kidney failure can cause high uric acid in blood due to diminished filtration ability and this can lead to gout. Gout can cause patients to have fatigue, joint pain, fever, chill, headache, nausea, uratoma, etc. If left untreated, gout will inturn worsen kidney damages and gout is often accompanied by high blood pressure, high blood lipid, type 2 diabetes and cardiovascular lesions.