In accordance with FAR 52.232-22 paragraph (f)(1) âThe Government is not obligated to reimburse the Contractor for costs incurred in excess of the total amount allotted by the Government to this contract.â FYXX funding has not yet been received.
Myofibrils account for roughly 80% of cellular volume, and are the contractile elements of the muscle cell. Myofibrils consist of repeating units called sarcomeres (the contractile unit of the myofibril), which have overlapping myofilaments connected to Z discs at either end of the sarcomere.
The sarcomere is the fundamental unit of muscle structure. Its capacity for contraction is the essential trait that makes muscles work.It has two primary components (1) thin filaments (each of which contains two strands of actin and a single strand of regulatory protein); and (2) thick filaments made of myosin (see diagram right).uring muscle contraction the thick filaments quickly slide along the thin filaments to shorten the myofibrils. The myofilaments themselves, however, do not contract. This is the action that give muscles their physical force.