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Atherosclerosis is a disease in which plaque builds up inside your arteries. Arteries are blood vessels that carry oxygen-rich blood to your heart and other parts of your body. Plaque is made up of fat, cholesterol, calcium, and other substances found in the blood. Over time, plaque hardens and narrows your arteries.This limits the flow of oxygen-rich blood to your organs and other parts of your body. Atherosclerosis can lead to serious problems, including heart attack, stroke, or even death.oronary Heart Disease. Coronary heart disease (CHD), also called coronary artery disease, occurs when plaque builds up in the coronary arteries. These arteries supply oxygen-rich blood to your heart. Plaque narrows the coronary arteries and reduces blood flow to your heart muscle.
The heart wall is composed of three layers. The middle layer, the myocardium, is responsible for the heartâs pumping action. Cardiac muscle, found only in the myocardium, contracts in response to signals from the cardiac conduction system to make the heart beat. Cardiac muscle is made from cells called cardiocytes. Like skeletal muscle cells cardiocytes have a striated appearance, but their overall structure is shorter and thicker.