When central nervous system involvement occurs, making an accurate diagnosis of the condition can be challenging, especially given the current definition for definite neurosarcoidosis requires histologic confirmation of the affected tissue (brain biopsy).
There is no disputing it. The oldest hamburger restaurant chain in the United States is White Castle. The first White Castle restaurant opened in Wichita, Kansas, in 1921. The first McDonald's didn't open until 1948, by comparison.
What is the oldest bar in Chicago? Schaller's Pump at 3417 S. South Halsted, has been in existence since 1889. It got the name pump from the fact that the Ambrosia brewery was located next door and the beer w â¦ as simply pumped in.