Noble County comprises the Kendallville, IN Micropolitan Statistical Area and is included in the Fort Wayne-Huntington-Auburn, IN Combined Statistical Area.
Current HIV/AIDS Guidelines Recommend. 1  If your T-cell count is above 500, you can hold off on HIV medications, but many experts feel it's good to start, just to be safe. 2  If your CD4 count is between 350 and 500, you should begin treatment to protect your immune system from future damage. If your T-cell count is below 350, or if you've ever had an AIDS-defining illness, you should start treatment immediately to avoid serious health problems.
The life cycle of HIV begins with viral entry, a multi-step interaction between the HIV envelope. and the host target cell surface receptors. In the initial step of entry, the HIV gp120 protein binds. to the host target cell CD4 receptor, thereby anchoring HIV to the host cell.