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The sugar in RNA is ribose, whereas the sugar in DNA is deoxyribose. The only difference between the two is that in deoxyribose, there is an oxygen missing from the 2' carbon â¦ (there is a H there instead of an OH).
Pentose Sugars. The pentose sugars ribose and deoxyribose are part of the nucleotides that make up the crucial nucleic acids like DNA and RNA. The highlighted area shows the difference between the two sugars.This sketch indicates how a sugar binds with a phosphate and a nitrogenous base to form a nucleotide.entose Sugars. The pentose sugars ribose and deoxyribose are part of the nucleotides that make up the crucial nucleic acids like DNA and RNA. The highlighted area shows the difference between the two sugars.