Other causes of chronic ankle pain include: 1  An injury to the nerves that pass through the ankle. 2  A torn or inflamed tendon. 3  Arthritis of the ankle joint.  A fracture in one of the bones that make up the ankle 1  joint. An inflammation of the joint lining (synovium)  The development of scar tissue in the ankle after a sprain.
Down syndrome can affect the nervous system of the body by causing the nerves to slow down or misfire at different times; it can also cause seizures to occur. While it can be detrimental on the nervous system, it is often more detrimental to the developmental systems of the body and the other systems which work to make the body function properly.
Trisomy 21: About 95% of people with Down syndrome have Trisomy 21. With this type of Down syndrome, each cell in the body has 3 separate copies of chromosome 21 instead of the usual 2 copies. Translocation Down syndrome: This type accounts for a small percentage of people with Down syndrome (about 3%).