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While the supplement may help you add calorie-burning muscle, some women may notice the number on the scale go up after taking creatine. That's because creatine supplementation causes your muscles to retain water, which may add extra weight.
DHEA levels are lower in women who have lupus (an autoimmune disorder that affects the skin and organs). DHEA may boost immune function. Several trials report that DHEA may lack an effect on SLE disease activity, though there is some evidence supporting its use in addition to regular treatment.