Most identifiersin the Java(TM) programming environment have either class or local scope. Instance and classvariables and methods have class scope; they can be used outside the class and its subclasses onlyby prefixing them with an instance of the class or (for class variables and methods) with the classname.
Acyclovir was the first successful antiviral agent in the world. It was originally synthesized in 1974 by Howard Schaeffer at Wellcome Research Laboratories (now GlaxoSmithKline).
NRTIs inhibit the reverse transcriptase (RT), an enzyme that controls the replication of the genetic material of the human immunodeficiency virus (HIV).The first NRTI was zidovudine, approved by the U.S. Food and Drug Administration (FDA) in 1987, which was the first step towards treatment of HIV.he first nucleoside reverse-transcriptase inhibitor with in vitro anti-HIV activity was zidovudine. Since zidovudine was approved in 1987, six nucleosides and one nucleotide reverse-transcriptase inhibitor (NRTI) have been approved by FDA.