Tretinoin was co-developed for its use in acne by James Fulton and Albert Kligman when they were at University of Pennsylvania in the late 1960s. The University of Pennsylvania held the patent for Retin-A, which it licensed to pharmaceutical companies.
/ËÊnËkÉËnstÉËtuËÊÉnlÌ/ /ËÊnËkÉnstÉËtjuËÊÉnlÌ/. adjective. Learner's definition of UNCONSTITUTIONAL. : not allowed by the constitution of a country or government: not constitutional.ËÊnËkÉËnstÉËtuËÊÉnlÌ/ /ËÊnËkÉnstÉËtjuËÊÉnlÌ/. adjective. Learner's definition of UNCONSTITUTIONAL. : not allowed by the constitution of a country or government: not constitutional.
The accordance of an act, law, or procedure with the provisions of a constitution. In the US, only the Supreme Court has the right of judicial review; that is, the authority to review and take action against any legislationâlocal, state, or federalâit deems to be unconstitutional.