When central nervous system involvement occurs, making an accurate diagnosis of the condition can be challenging, especially given the current definition for definite neurosarcoidosis requires histologic confirmation of the affected tissue (brain biopsy).
There is no disputing it. The oldest hamburger restaurant chain in the United States is White Castle. The first White Castle restaurant opened in Wichita, Kansas, in 1921. The first McDonald's didn't open until 1948, by comparison.
World's Oldest Hamburger? McDonald's Burger From 1999 Almost Looks New (VIDEO) Utah man David Whipple has managed to hang on to a hamburger from McDonald's since 1999. The extraordinary part isn't the fact that he didn't throw the burger out, though -- it's that the burger barely looks like it has aged.