Cervical spine fractures can occur secondary to exaggerated flexion or extension, or because of direct trauma or axial loading. Pathology. The cervical spine is susceptible to injury because it is highly mobile with relatively small vertebral bodies and supports the head which is both heavy and acts as a lever.
The inactive molecule pepsinogen is cleaved in a strongly acidic environment to give off the active enzyme, pepsin. Pepsinogen is produced in the stomach by chief cells.
Pepsin is expressed as a pro-form zymogen, pepsinogen, whose primary structure has an additional 44 amino acids. In the stomach, chief cells release pepsinogen.epsin will digest up to 20% of ingested amide bonds by cleaving preferentially after the N-terminal of aromatic amino acids such as phenylalanine, tryptophan, and tyrosine.