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An enlarged heart is medically known as cardiomegaly. Cardiomegaly can be caused by a number of different conditions, including diseases of the heart muscle or heart valves, high blood pressure, arrhythmias, and pulmonary hypertension. Cardiomegaly can also sometimes accompany longstanding anemia and thyroid diseases, among other conditions. Infiltrative diseases of the heart, for example, in which abnormal proteins (amyloidosis) or excess iron (hemochromatosis) accumulate within the tissues of the heart, can also cause an enlargement of the heart.
Genetic disorders that cause fat, protein, or other substances to build up; Abnormal growths may cause an enlarged liver. These may be due to: Cysts; Tumors that start in or spread to the liver; A problem with blood flow. This may be due to a variety of conditions such as: Congestive heart failure, a condition where the heart doesn't pump blood well