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The term ' segmentation gene ' is a classification given to a broad class of genes that are further subdivided into three smaller classes of genes. Within the segmentation gene group, there are gap genes, pair-rule genes and segment polarity genes.They control development in this order.These segmentation genes control the development of segments, or small repeated regions of a body that make up specific structures. If you were to look at a fly embryo during development, you'd quickly notice these segments along their bodies.hey control development in this order. These segmentation genes control the development of segments, or small repeated regions of a body that make up specific structures. If you were to look at a fly embryo during development, you'd quickly notice these segments along their bodies.
The gene responsible for HGPS is called LMNA (pronounced âlamin-aâ). Within this gene there is a change in one piece of DNA that is responsible for Progeria. This type of gene change is called a point mutation. The LMNA gene makes a protein called Lamin A, which is an important protein for most cells of our bodies. Lamin A is found in the cell nucleus (the part of each cell that contains the DNA), and helps maintain the shape and function of the cell. The point mutation compromises that cell integrity, causing Progeria.