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All-or-none Response: Phenomenon in which a muscle fiber contracts completely when exposed to a threshold stimulus, or not at all. When a skeletal muscle is stimulated to contract by a motor neuron a minimum amount of stimulus is needed to start the process of muscle contraction.
A single action potential in a motor neuron is sufficient to produce an action potential in a skeletal-muscle fiber. Table 11-2 summarizes the events leading to the contraction of a skeletal-muscle fiber. Muscle fibers form ATP by the transfer of phosphate from creatine phosphate to ADP, by oxidative phosphorylation of ADP in mitochondria, and by substrate-level phosphorylation of ADP in the glycolytic pathway. 2  At the beginning of exercise, muscle glycogen is the major fuel consumed.