In bacteria, transcription begins with the binding of RNA polymerase to the promoter in DNA. RNA polymerase is a core enzyme consisting of five subunits: 2 Î± subunits, 1 Î² subunit, 1 Î²' subunit, and 1 Ï subunit.
Untreated gout can cause a risk for diabetes and heart disease. Chronic gout can also cause kidney stones. Gout is caused by a buildup of uric acid in the blood. It cristalizes in the joints, with the big toe being the location in half of the cases. This is called podagra.
Health Impact of Stress. Stress can negatively affect the bodyâs normal functions including the digestive and waste systems. Stress has also been shown to deplete vitamin B5 from the body. Vitamin B5 helps the body to excrete excess uric acid from the body. Therefore, stress may trigger a gout attack.