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Anaphylactic reactions are excluded by the presence of red plasma or urine, discordant pretransfusion and posttransfusion ABO blood types, or a positive direct antiglobulin (Coombs) test result. Demonstration of anti-IgA in a pretransfusion sample of the recipient's serum or plasma establishes the diagnosis.
Autoantibodies have been noted after transfusion and can present in. American Proficiency Institute â 2010 1 st Test Event EDUCATIONAL COMMENTARY â WARM AUTOANTIBODIES AND TRANSFUSION (cont.) patients weeks to months later as a delayed transfusion reaction.