When central nervous system involvement occurs, making an accurate diagnosis of the condition can be challenging, especially given the current definition for definite neurosarcoidosis requires histologic confirmation of the affected tissue (brain biopsy).
There is no disputing it. The oldest hamburger restaurant chain in the United States is White Castle. The first White Castle restaurant opened in Wichita, Kansas, in 1921. The first McDonald's didn't open until 1948, by comparison.
White Castle is an American regional fast-food hamburger chain. It is the first American hamburger fast food restaurant chain.[1] White Castle is known for small square burgers, sometimes referred to, and today trademarked as âSlyders.â[2] They were priced at five cents until the 1940s, and remained at ten cents for years thereafter while shrinking.