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While the supplement may help you add calorie-burning muscle, some women may notice the number on the scale go up after taking creatine. That's because creatine supplementation causes your muscles to retain water, which may add extra weight.
For the use of creatine to increase athletic performance, see Creatine supplements. Not to be confused with creatinine. Creatine (/ËkriËÉtiËn/ or /ËkriËÉtÉªn/) is a nitrogenous organic acid that occurs naturally in vertebrates and helps to supply energy to all cells in the body, primarily muscle.This is achieved by increasing the formation of adenosine triphosphate (ATP).ynthesis primarily takes place in the kidney and liver, with creatine then being transported to the muscles via the blood. Approximately 95% of the human body's total creatine is located in skeletal muscle.