Because the potatoes grow inside the hay bale, the bale can be positioned in areas where the soil is unsuitable for gardening or even on top of paved areas. However, water does drain from the bottom of the bale, so choose an area where this is not an issue.
Bacteria have exhibited colistin resistance in the past, but this time it is different: Previous forms of the resistance weakened the microbes, and the resistance genes were located on DNA that was not easily shared among bacteria.
Mitochondria divide by simple fission, splitting in two just as bacterial cells do, and although the DNA replication strategies are a little different, forming displacement or D-loop structures, they partition their circular DNA in much the same way as do bacteria.