Angelman syndrome (AS) is a rare neuro-genetic disorder that occurs in one in 15,000 live births. Angelman syndrome is often misdiagnosed as cerebral palsy or autism due to lack of awareness. Characteristics of the disorder include developmental delay, lack of speech, seizures, and walking and balance disorders. Individuals with Angelman syndrome will require life-long care.
Description of Estrogen receptor assay. Estrogen receptor assay: A laboratory test that evaluates the benefits of hormone treatment for a patient diagnosed with breast cancer.
1 Once inside a target cell, the hormone (pink) binds to a receptor (purple) - similar to a hand sliding in a glove or mitten-and forms what is known as a hormone-receptor complex between the ligand and receptor.2  A ligand is any molecule that binds to a specific site on a protein or other molecule. In this case, the estrogen hormone 17-beta-estradiol is the ligand, and the estrogen receptor is the protein. 2  Binding turns on, or activates, a hormone receptor. 3  Activation sets in motion cell signaling systems that trigger gene expression and lead to responses typical of a particular hormone.