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Prescription drugs that may cause bullous pemphigoid include penicillin, etanercept (Enbrel), sulfasalazine (Azulfidine) and furosemide (Lasix). Light and radiation. Ultraviolet light therapy to treat certain skin conditions may trigger bullous pemphigoid, as can radiation therapy to treat cancer.
Bullous pemphigoid is an autoimmune disease that causes blistering of the skin. 1  Bullous pemphigoid occurs when the immune system attacks the skin and causes blistering. 2  People develop large, itchy blisters with areas of inflamed skin.