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The damage to the femoral nerve can be caused by compression, trauma, and disease such as diabetes. Patients suffering from femoral neuropathy complain of pain that radiates into the front of the thigh and the mid-calf and is associated with weakness of the quadriceps muscle causing the knee to buckle.he damage to the femoral nerve can be caused by compression, trauma, and disease such as diabetes. Patients suffering from femoral neuropathy complain of pain that radiates into the front of the thigh and the mid-calf and is associated with weakness of the quadriceps muscle causing the knee to buckle.
Click to read more below. The femoral nerve is the major nerve that serves the tissues of the thigh and leg, including the muscles and skin. While the much larger sciatic nerve also passes through the thigh on its way to the lower leg and foot, only the femoral nerve innervates the tissues of the thigh.Nerve signals carried by the femoral nerve are crucial to the function of the legs, including standing, walking, and running.hile the much larger sciatic nerve also passes through the thigh on its way to the lower leg and foot, only the femoral nerve innervates the tissues of the thigh. Nerve signals carried by the femoral nerve are crucial to the function of the legs, including standing, walking, and running.