1 The most common causes of pleural effusion are congestive heart failure, pneumonia, malignancies and pulmonary embolism. 2  Signs and symptoms of pleural effusion include: 3  Shortness of breath. 4  Chest pain. 5  Associate symptoms of pleural effusion due to an underlying disease include: 6  Night sweats. 7  Coughing up blood. 8  Fever.
Leg Pain. Varicose vein disease is a common and often underappreciated cause of leg pain. Varicose veins may be overlooked as a cause of leg pain because not all varicose veins bulge on the surface; some are invisible and located deeper in the leg. Leaking varicose veins cause blood to pool and waste products to accumulate in the leg.
The excess blood in the failed veins then makes the veins swell, and the swollen veins can leak blood and fluid into the surrounding tissue of the leg. This blood and fluid that has leaked into the surrounding tissue of the leg often causes skin discoloration, itching, and inflammation of the leg tissue. This inflammation and leakage of the blood and fluid into the leg tissue can cause the leg skin to feel a hot or burning sensation. The vein problem âVenous Refluxâ that often causes the veins to fail and causes the hot and burning sensation to be experienced is now easily treated with modern vein procedures.