Biography and career. Satterfield was born Louis Edward in Shaw, Mississippi, a city in Bolivar and Sunflower counties, Mississippi, in the Mississippi Delta region, on April 3, 1937.
Excitation-contraction coupling (ECC) is the process whereby an action potential triggers a myocyte to contract.When a myocyte is depolarized by an action potential, calcium ions enter the cell during phase 2 of the action potential through L-type calcium channels located on the sarcolemma.hen calcium binds to the TN-C, this induces a conformational change in the regulatory complex such that troponin-I (TN-I) exposes a site on the actin molecule that is able to bind to the myosin ATPase located on the myosin head.
Second region âthat generates a signal when the hormone binds to it. The dual function of binding and coupling (signal generation) ultimately defines a receptor. It is the coupling of hormone binding to signal transduction called, receptor â effector coupling.This is the first step in the amplification of hormonal response. This dual purpose also distinguishes the receptor from the plasma protein that also bind hormone but do not generate signal.Chemical Nature of Receptor. Receptors are proteins. Several classes of peptide receptors have been identified.ormone âreceptor interaction occurs that results in the generation of an intracellular signal. Intracellular signal can either regulate the activity of a select set of genes, leading to alteration in the amount of certain proteins in the target cell.