Most inflamed muscles cause a burning and cramping sensation when strained. The abdominal muscles make the abdominal wall so any injury to these muscles are felt superficially. There are some deep lying muscles that can also be strained and may therefore be the cause of a deeper burning sensation in the abdomen.
Six to eight cycles of chemotherapy (anthracycline or non-anthracycline-containing regimen) with Perjeta and Herceptin, followed by Perjeta and Herceptin every three weeks for a total of one year (52 weeks) of treatment.
1 Advise patients of these risks and the need for effective contraception.  Based on its mechanism of action and findings in animal studies, PERJETA can cause fetal harm when administered to a pregnant woman. PERJETA is a HER2/neu receptor antagonist. Cases of oligohydramnios and oligohydramnios sequence manifesting as pulmonary hypoplasia, skeletal abnormalities, and neonatal death have been reported with use of another HER2/neu receptor antagonist (trastuzumab) during pregnancy.