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Hypersecretion of growth hormone causes gigantism in children and acromegaly in adults. Evaluation of growth hormone hypersecretion cannot be excluded with a single normal GH level due to diurnal variation.However, a random blood sample showing markedly elevated GH is adequate for diagnosis of GH hypersecretion.n humans, this condition is caused by over-production of growth hormone in childhood resulting in persons between 2.13 m (7 feet or 84 inches) and 2.74 m (9 feet or 108 inches) in height.
Acromegaly. A rare disease resulting from excessive growth hormone caused by a benign tumor. If such a tumor develops within the first 10 years of life, the result is gigantism (in which growth is accelerated) and not acromegaly. chronic metabolic condition in adults caused by oversecretion of growth hormones by the pituitary gland. It is characterized by gradual, marked soft tissue enlargement and widening and thickening of skeletal bones in the face, jaw, hands, and feet. Hypertrophy of the vocal cords leads to deepening of the voice.