Angelman syndrome (AS) is a rare neuro-genetic disorder that occurs in one in 15,000 live births. Angelman syndrome is often misdiagnosed as cerebral palsy or autism due to lack of awareness. Characteristics of the disorder include developmental delay, lack of speech, seizures, and walking and balance disorders. Individuals with Angelman syndrome will require life-long care.
Description of Estrogen receptor assay. Estrogen receptor assay: A laboratory test that evaluates the benefits of hormone treatment for a patient diagnosed with breast cancer.
During androgen-independent progression, prostate cancer relies on various cellular pathways, some involving the androgen receptor and others bypassing it. In the former type of pathway, a mutated androgen receptor may be activated by various ligands.he androgen dihydrotestosterone binds to the androgen receptor, dissociating it from heat-shock proteins. The dihydrotestosterone-bound androgen receptor translocates into the nucleus, dimerizes, and binds to the androgen-response elements, thereby activating genes involved in cell growth.