In bacteria, transcription begins with the binding of RNA polymerase to the promoter in DNA. RNA polymerase is a core enzyme consisting of five subunits: 2 Î± subunits, 1 Î² subunit, 1 Î²' subunit, and 1 Ï subunit.
Untreated gout can cause a risk for diabetes and heart disease. Chronic gout can also cause kidney stones. Gout is caused by a buildup of uric acid in the blood. It cristalizes in the joints, with the big toe being the location in half of the cases. This is called podagra.
Medications can also play a role in gout attacks. Diuretic pills used to treat blood pressure can be a cause of chronic gout. Medications that compromise your kidneys can also be a cause of gout pain. The symptoms of gout can be similar to other forms of arthritis. Here are 10 of the most common symptoms of gout. If you suffer from one or more of these symptoms, talk to your doctor.