Adrenal insufficiency - Causes. 1  Causes of acute adrenal insufficiency are mainly sudden withdrawal of long-term corticosteroid therapy, Waterhouse-Friderichsen syndrome, and stress in people with underlying chronic adrenal insufficiency.
Lipoatrophy is a common complication of protease inhibitor administration in HIV patients. These are antiretroviral medications that may lead to central fat accumulation and fat tissue loss in other parts of the body. Lipoatrophy caused by HIV medications are usually generalized or total.
Some of these body changes are caused by the HIV medicines, but they rarely occur with the medicines that are most often used nowadays. Lipoatrophy is most common with medicines such as d4T (stavudine, Zerit) and AZT (ZDV, zidovudine), which are infrequently used in the United States at present.