Vaccine Adverse Events. The smallpox vaccine is generally safe and effective, but some people do experience side effects and adverse reactions. Severe adverse reactions are more common in people who are being vaccinated for the first time and among young children (<5 years of age). CDC has published criteria to use for surveillance case definition and classification for smallpox vaccine (vaccinia) adverse reactions.
According to the American Express survey, the average wedding gift is $144 for a family member and $97 for a close friend. More affluent wedding guests give an average wedding gift worth $251 for any wedding they attend, while co-workers come in at the low end of the scale at an average of $66.
While $31,213 is the average cost of weddings through the entire U.S., weddings in some cities cost more than double that figure. The biggest spenders hosted weddings in Manhattan, where the average wedding cost $76,328. Next up was Long Island with a cost of $55,327, followed by New Jersey ($53,986) and the Westchester/Hudson Valley area ($52,954) of New York. Chicago weddings rounded out the top five with an average cost of $50,934.