What is a migraine with aura, and what causes it? Scientists arenât sure what causes migraines with aura. Itâs thought that at least two brain chemicals called serotonin and dopamine play a role. According to the theory, something goes awry in the way these chemicals regulate brain function. This may cause the brain and the bodyâs immune system to overreact.
The 1899 Spiders set the major league record for most consecutive losses in a season (24, from July 26 to September 16), and had six losing streaks of 10 games or more.
In 2012 the Cardinals became the first NFL franchise to lose 700 games since its inception. The franchise's all-time win-loss record (including regular season and playoff games) at the conclusion of the 2014 season is 528â729â39 (522â721â39 in the regular season, 6â8 in the playoffs).