Most identifiersin the Java(TM) programming environment have either class or local scope. Instance and classvariables and methods have class scope; they can be used outside the class and its subclasses onlyby prefixing them with an instance of the class or (for class variables and methods) with the classname.
Acyclovir was the first successful antiviral agent in the world. It was originally synthesized in 1974 by Howard Schaeffer at Wellcome Research Laboratories (now GlaxoSmithKline).
It was initially approved by the FDA in 2012 for patients with metastatic HER2-positive breast cancer, and pertuzumab is the first drug approved by the FDA for the neoadjuvant treatment of breast cancer. The FDA also largely based the accelerated approval on data from the NeoSphere study.