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Anaphylactic reactions are excluded by the presence of red plasma or urine, discordant pretransfusion and posttransfusion ABO blood types, or a positive direct antiglobulin (Coombs) test result. Demonstration of anti-IgA in a pretransfusion sample of the recipient's serum or plasma establishes the diagnosis.
A blood transfusion is a procedure used to give you blood through an IV. The IV is placed into a large vein, usually in your arm. You may get only part of the blood, such as red blood cells, platelets, or plasma. Transfusions are usually done in the hospital or in a transfusion center.