Erythropoiesis = formation of erythrocytes. 1  the body must produce about 2.5 million new RBCs every second. 2  in adults, erythropoiesis occurs mainly in the marrow of the sternum, ribs, vertebral processes, and skull bones. 3  begins with a cell called a hemocytoblast or stem cell (below)  rate is regulated by oxygen levels:
1 Second Intention Healing â A wound that is extensive and involves considerable tissue loss, and in which the edges cannot be brought together heals in this manner. 2  This is how pressure ulcers heal. 3  Secondary intention healing differs from primary intention healing in three ways:
Healing by secondary intention In this form of healing the wound is left open and allowed to heal by granulation.It is appropriate to use secondary healing when there is tissue loss and a woundcan not be closed because the edges will not approximate.