Hippocrates did exist (although some scholars dispute even this) and was well known in the Greek world. Apparently born about 460 B.C. on the island of Cos, he died about 370 in Thessaly. He was a teacher on Cos, an itinerant practitioner of medicine, and the presumed author of a number of treatises.
Males: Castration is a relatively minor operation, which can be performed as soon as the testicles descend (10-12 weeks) although most vets wait until the rabbit is 4-5 months old. The testicles are removed via the scrotum or the lower abdomen.p to 80% of unsprayed female rabbits develop uterine cancer by the age of 5. Females who are not spayed when young and in good health may have to undergo the operation as an emergency in later life (e.g. cancer or pyometra) develops.
For Flemish Giants, this is 14 pounds, and a typical rabbit will reach this weight when they are about 9 months to one year. A Flemish Giant can take up to 1.5 years to reach their maximum weight and a breeder should wait until the rabbit is slightly over a year old before breeding. Females and males can become sexually mature at 4 months and 8 days.