frameshift mutation / frame-shift mutation; frameshift. A frameshift mutation is a genetic mutation caused by a deletion or insertion in a DNA sequence that shifts the way the sequence is read. A DNA sequence is a chain of many smaller molecules called nucleotides.
As for Flexeril (cyclobenzaprine) is is not a controlled substance under US, Canadian, or international law. Some drugs used as muscle relaxants ARE controlled substances like Valium and many US states and countries have listed Soma (carisoprodol) as a controlled substance (or prohibited it).
Can I take Flexiril? Flexeril (cyclobenzaprine) does not have any ill effects on the kidney. Before you take this medication with chronic kidney disease, you must make sure that there this medication does not interfere with any other medication that you are taking. You should discuss this with your physician who knows all of the medication that you are taking.