1 The most common causes of pleural effusion are congestive heart failure, pneumonia, malignancies and pulmonary embolism. 2  Signs and symptoms of pleural effusion include: 3  Shortness of breath. 4  Chest pain. 5  Associate symptoms of pleural effusion due to an underlying disease include: 6  Night sweats. 7  Coughing up blood. 8  Fever.
Leg Pain. Varicose vein disease is a common and often underappreciated cause of leg pain. Varicose veins may be overlooked as a cause of leg pain because not all varicose veins bulge on the surface; some are invisible and located deeper in the leg. Leaking varicose veins cause blood to pool and waste products to accumulate in the leg.
Varicose veins and venous insufficiency. Varicose veins are swollen, twisted, and enlarged veins that you can see under the skin. They are often red or blue in color. They usually appear in the legs, but can occur in other parts of the body. Normally, one-way valves in your leg veins keep blood moving up toward the heart. When the valves do not work properly, they allow blood to back up into the vein. The vein swells from the blood that collects there, which causes varicose veins.