The infectious agents associated with neonatal sepsis have changed since the mid-20th century. During the 1950s, S aureus and E coli were the most common bacterial pathogens among neonates in the United States.
Common diphenhydramine side effects may include: 1  dizziness, drowsiness, loss of coordination; 2  dry mouth, nose, or throat; 3  constipation, upset stomach;  dry eyes, blurred vision; 1  or. day-time drowsiness or hangover feeling after night-time  use.
Due to its strong anticholinergic effects, diphenhydramine is on the  Beers list  of drugs to avoid in the elderly. Diphenhydramine is category B in the FDA Classification of Drug Safety During Pregnancy. It is also excreted in breast milk. Paradoxical reactions to diphenhydramine have been documented, in particular among children, and it may cause excitation instead of sedation.