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Patients with cardiomyopathy, a stiffening and thickening of the heart muscle that weakens it, may develop an enlarged heart as it labors to pump an adequate supply of blood to the body. Coronary artery disease, in which plaque in the arteries interferes with the flow of blood, can cause the heart to enlarge.
What causes heart block? Heart block can be caused by: Scarring (fibrosis) of the heart's electrical system caused by aging. This is the most common cause of heart block. Heart attacks. Infection of the heart valves (endocarditis). Complication of Lyme disease. Sarcoidosis or hemochromatosis.