1 The most common causes of pleural effusion are congestive heart failure, pneumonia, malignancies and pulmonary embolism. 2  Signs and symptoms of pleural effusion include: 3  Shortness of breath. 4  Chest pain. 5  Associate symptoms of pleural effusion due to an underlying disease include: 6  Night sweats. 7  Coughing up blood. 8  Fever.
Leg Pain. Varicose vein disease is a common and often underappreciated cause of leg pain. Varicose veins may be overlooked as a cause of leg pain because not all varicose veins bulge on the surface; some are invisible and located deeper in the leg. Leaking varicose veins cause blood to pool and waste products to accumulate in the leg.
It causes swelling (edema) of the legs. It can also cause sores on the legs. Muscles in your feet and legs help your veins move blood to the heart against gravity. The veins also have one-way valves that keep the blood from flowing backwards. The valves work like one-way gates.