Assignment of Medicare-Approved Amount. In most instances, Medicare pays 80% of the approved amount of doctor bills; you or your medigap plan pay the remaining 20%, if your doctor accepts assignment of that amount as the full amount of your bill. Most doctors who treat Medicare patients will accept assignment.
1 Dominant diseases: single gene disorders that occur when an individual has one altered copy of the relevant gene and one healthy copy. For example, Huntingtonâs disease.  Recessive diseases: single gene disorders that only occur when an individual has two altered versions of the relevant gene.
In single-gene diseases, a mutation in just one of these genes is responsible for disease. Single-gene diseases run in families and can be dominant or recessive, and autosomal or sex-linked.Pedigree analyses of large families with many affected members are very useful for determining the inheritance pattern of single-gene diseases. Table 1 includes some examples of single-gene diseases.n single-gene diseases, a mutation in just one of these genes is responsible for disease. Single-gene diseases run in families and can be dominant or recessive, and autosomal or sex-linked.