Tretinoin was co-developed for its use in acne by James Fulton and Albert Kligman when they were at University of Pennsylvania in the late 1960s. The University of Pennsylvania held the patent for Retin-A, which it licensed to pharmaceutical companies.
/ËÊnËkÉËnstÉËtuËÊÉnlÌ/ /ËÊnËkÉnstÉËtjuËÊÉnlÌ/. adjective. Learner's definition of UNCONSTITUTIONAL. : not allowed by the constitution of a country or government: not constitutional.ËÊnËkÉËnstÉËtuËÊÉnlÌ/ /ËÊnËkÉnstÉËtjuËÊÉnlÌ/. adjective. Learner's definition of UNCONSTITUTIONAL. : not allowed by the constitution of a country or government: not constitutional.
1. (Historical Terms) history US a clause in the constitutions of several Southern states that waived electoral literacy requirements for lineal descendants of people voting before 1867, thus ensuring the franchise for illiterate White people: declared unconstitutional in 1915.