Confidence votes 406. Muscle contraction is regulated by calcium ions, which will change thin filament into an activated state by binding to troponin. The binding of calcium to the troponin changes it's shape so the myosin binding sites on the actin (thin filament) are exposed. bind to regulatory sites on troponin to remove contraction inhibition.
By Mayo Clinic Staff. A high uric acid level, or hyperuricemia, is an excess of uric acid in your blood. Uric acid is produced during the breakdown of purines, which are found in certain foods and are also formed by your body. Once produced, uric acid is carried in your blood and passes through your kidneys, where most of it is filtered out into the urine. About one in five people has a high uric acid level.
Excessive salt craving may indicate an underlying medical condition, such as Addison's disease.