When central nervous system involvement occurs, making an accurate diagnosis of the condition can be challenging, especially given the current definition for definite neurosarcoidosis requires histologic confirmation of the affected tissue (brain biopsy).
There is no disputing it. The oldest hamburger restaurant chain in the United States is White Castle. The first White Castle restaurant opened in Wichita, Kansas, in 1921. The first McDonald's didn't open until 1948, by comparison.
And it worked. Just two years later, White Castle expanded to El Dorado, KS, and then Omaha, NE, to feed customers sacks of 5-cent small burgers (now commonly known as âslidersâ), becoming the first fast food hamburger chain in the world, according to the companyâs own historical account.