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While the supplement may help you add calorie-burning muscle, some women may notice the number on the scale go up after taking creatine. That's because creatine supplementation causes your muscles to retain water, which may add extra weight.
In short, creatine can help you train heavier for more reps; it also draws water into the muscles, making you look full in appearance. The timing on the creatine is not critical. You can use it before or after your workout, or anytime throughout the day.