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While the supplement may help you add calorie-burning muscle, some women may notice the number on the scale go up after taking creatine. That's because creatine supplementation causes your muscles to retain water, which may add extra weight.
Once in the muscle, some of the creatine is spontaneously converted to creatinine. The amount of both creatine and creatinine depend on muscle mass, so men usually have higher levels than women. Creatine is now available as a dietary supplement.