Adrenal insufficiency - Causes. 1  Causes of acute adrenal insufficiency are mainly sudden withdrawal of long-term corticosteroid therapy, Waterhouse-Friderichsen syndrome, and stress in people with underlying chronic adrenal insufficiency.
Lipoatrophy is a common complication of protease inhibitor administration in HIV patients. These are antiretroviral medications that may lead to central fat accumulation and fat tissue loss in other parts of the body. Lipoatrophy caused by HIV medications are usually generalized or total.
Lipogenesis is the process by which acetyl-CoA is converted to fatty acids.The former is an intermediate stage in metabolism of simple sugars, such as glucose, a source of energy of living organisms. Through lipogenesis and subsequent triglyceride synthesis, the energy can be efficiently stored in the form of fats.nsulin stimulates lipogenesis primarily by activating two enzymatic pathways. Pyruvate dehydrogenase (PDH), converts pyruvate into acetyl-CoA. Acetyl-CoA carboxylase (ACC), converts acetyl-CoA produced by PDH into malonyl-CoA.