adjective. 1  regardless of sin reparar en; buy it regardless of the cost cÃ³mpralo, cueste lo que cueste; they shot them all regardless of rank los fusilaron a todos sin miramientos a su graduaciÃ³n; we did it regardless of the consequences lo hicimos sin tener en cuenta las consecuencias.
Yes, their are two active ingredients in tramacet. Tramadol hydrochloride and paracetamol. Tramadol hydrochloride is an opioid and is closely related to morphine. It is actually synthetic form of morphine.
Ultram contains tramadol, an opioid agonist and inhibitor of norepinephrine and serotonin re-uptake. Although the mode of action is not completely understood, the analgesic effect of tramadol is believed to be due to both binding to Âµ-opioid receptors and weak inhibition of re-uptake of norepinephrine and serotonin.