Biography and career. Satterfield was born Louis Edward in Shaw, Mississippi, a city in Bolivar and Sunflower counties, Mississippi, in the Mississippi Delta region, on April 3, 1937.
Excitation-contraction coupling (ECC) is the process whereby an action potential triggers a myocyte to contract.When a myocyte is depolarized by an action potential, calcium ions enter the cell during phase 2 of the action potential through L-type calcium channels located on the sarcolemma.hen calcium binds to the TN-C, this induces a conformational change in the regulatory complex such that troponin-I (TN-I) exposes a site on the actin molecule that is able to bind to the myosin ATPase located on the myosin head.
See Excitation-contraction coupling. T-tubules are the major sites for the coupling of excitation and contraction, which is the process whereby the spreading depolarization is converted into force production by muscle fibers.ransverse tubules are invaginations of the sarcolemma. Though the invaginations are normally perpendicular to the length of the fiber, many T-tubules can lie axial to the long-axis of the fiber, both wrapping around and running alongside myofilament bundles.