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Rating Newest Oldest. Best Answer: Nucleotides are the building blocks of DNA, these nucleotides are formed by three parts: 1) A Nitrogenous Base, that are divided in Purines (Adenine, Guanine) and Pyrimidines ( Cytosine, Thymine, Uracil) 2) 1 Molecule of Phosporic Acid (in its Phosphate form) joined by ester bonds to 3) below.
blocks thymidylate synthase, which is an enzyme that catalyzes the conversion of deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP). dTMP is one of the three nucleotides (dTMP, dTTP, and dTDP) that form thymine. when this process is inhibited, DNA damage occurs, and cancer cell can die.