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Extramedullary disease (EMD) occurs when myeloma. cells form tumors outside the bone marrow in the soft. tissues or organs of the body. While myeloma resides mainly within the bone. marrow, EMD can be present at the time of initial. diagnosis or at the time of disease relapse following. treatment-induced remission.
extrapyramidal system a functional, rather than anatomical, unit comprising the nuclei and fibers (excluding those of the pyramidal tract) involved in motor activities; they control and coordinate especially the postural, static, supporting, and locomotor mechanisms.ee extrapyramidal system (below). extrapyramidal system. a functional, rather than anatomical, unit comprising the nuclei and fibers (excluding those of the pyramidal tract) involved in motor activities; they control and coordinate especially the postural, static, supporting and locomotor mechanisms.