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Signs and symptoms of knee effusion include: 1  Puffiness and swelling in the knee. 2  Pain when bearing weight. 3  Stiffness or reduced range of motion due to increased fluid.  One knee appears noticeably larger than the 1  other. May feel warm to the touch.
1 Knee effusion: Fluid buildup inside the knee, usually from inflammation. 2  Any form of arthritis or injury may cause a knee effusion. 3  Meniscal tear: Damage to a meniscus, the cartilage that cushions the knee, often occurs with twisting the knee. 4  Large tears may cause the knee to lock. Knee effusion: Fluid buildup inside the knee, usually from inflammation. 2  Any form of arthritis or injury may cause a knee effusion. 3  Meniscal tear: Damage to a meniscus, the cartilage that cushions the knee, often occurs with twisting the knee. 4  Large tears may cause the knee to lock.