Approximately 30 motor freight companies serve the area. The Virginia Inland Port is located in Front Royal off Interstate 81, just 85 miles north of Waynesboro. The International Port Hampton Roads (185 miles) is the largest natural deep water harbor in the world.
The organic nitrates, including nitroglycerin, isosorbide dinitrate and isosorbide mononitrate, act as prodrugs for nitric oxide (NO) which is a potent vasodilator gas. Nitric oxide activates guanylyl-cyclase in vascular endothelial cells, which increases intracellular cyclic GMP and thereby reduces intracellular calcium concentrates and dephosphorylates myosin light chains causing relaxation of smooth muscle cells.
Silver nitrate is used in many ways in organic synthesis, e.g. for deprotection and oxidations. Ag+ binds alkenes reversibly, and silver nitrate has been used to separate mixtures of alkenes by selective absorption.The resulting adduct can be decomposed with ammonia to release the free alkene.lbertus Magnus, in the 13th century, documented the ability of nitric acid to separate gold and silver by dissolving the silver. Magnus noted that the resulting solution of silver nitrate could blacken skin.