Approximately 30 motor freight companies serve the area. The Virginia Inland Port is located in Front Royal off Interstate 81, just 85 miles north of Waynesboro. The International Port Hampton Roads (185 miles) is the largest natural deep water harbor in the world.
The organic nitrates, including nitroglycerin, isosorbide dinitrate and isosorbide mononitrate, act as prodrugs for nitric oxide (NO) which is a potent vasodilator gas. Nitric oxide activates guanylyl-cyclase in vascular endothelial cells, which increases intracellular cyclic GMP and thereby reduces intracellular calcium concentrates and dephosphorylates myosin light chains causing relaxation of smooth muscle cells.
Nitrate (NO 3 1-) is a polyatomic ion. It is made up of one nitrogen and three oxygen atoms. It is part of many important molecules. Potassium nitrate is a common nitrate, used in fertilizers because plants need nitrates to live and grow.Some nitrates are explosive. People make large amounts of nitrates from ammonia.Nitrates are similar to nitrites. Nitric acid has the formula HNO 3 and has no overall charge, because the hydrogen ion is positive.otassium nitrate is a common nitrate, used in fertilizers because plants need nitrates to live and grow. Some nitrates are explosive. People make large amounts of nitrates from ammonia.