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We also hear from many women with concerns about âestrogen dominanceâ â a state of high estrogen levels blamed for a wide range of distressing symptoms as well as fibroids, endometriosis, hypothyroidism and breast cancer, too.
Causes of High Estrogen Levels. There are many factors that can cause high estrogen levels in women, with pregnancy and the lead up to menopause being common hormonal triggers. Another cause is a woman's menstrual cycle. Levels of the estrogen, estradiol, have been recorded at an average of 400pg/ml for most women during ovulation.