Our Companies. The Main Street America Group was established in 1923 with the founding of National Grange Mutual Insurance Company (NGM), which was created to provide affordable insurance coverage to Grange Fraternity members in New Hampshire.
Autoimmune progesterone dermatitis is a rare disease caused by an autoimmune response to endogenous progesterone in women during their reproductive years [1]. Skin lesions typically occur due to increases in progesterone during the luteal phase of the menstrual cycle [2].
This is when the blood level of the sex-hormone progesterone rises. The skin rash happens as an autoimmune response to the body's own progesterone, hence its name. Within a few days of menstruation when progesterone level falls, there is partial to complete resolution of the rash. It will recur during the next cycle.