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Liposarcoma is a malignant tumor that arises in fat cells in deep soft tissue, such as that inside the thigh or in the retroperitoneum. Liposarcoma is a rare type of cancer that bears a resemblance to fat cells when examined under a microscope. dedifferentiated liposarcoma has a poorly differentiated component, that is not identifiable as a liposarcoma (left edge of image), and a differentiated component with lipoblasts and increased vascularity (right of image).
Osteosarcoma is a type of bone cancer that develops in undifferentiated cells and occurs at the ends of long bones, especially around the knee. Approximately 900 new cases of osteosarcoma are reported each year in the U.S., occurring most often in children, adolescents, and young adults.