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Midol is a combination, over-the-counter (OTC) drug used to relieve menstrual symptoms, including cramps and bloating.Combination OTC drugs for menstrual symptoms generally include both a pain reliever and a diuretic -- a medication that relieves bloating by causing your body to release excess fluids.Midol contains acetaminophen as a pain reliever and caffeine as a diuretic.Midol is a brand name medication, though generic equivalents are available as well.ombination OTC drugs for menstrual symptoms generally include both a pain reliever and a diuretic -- a medication that relieves bloating by causing your body to release excess fluids.
A: According to the Midol website, depending on the product, the main ingredients in Midol are either acetaminophen or a nonsteroidal anti-inflammatory drug, such as ibuprofen or naproxen sodium. Each of the formulations available as of October 2014 contains additional ingredients, including caffeine, antihistamines, diuretics and sleep aids.