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Liposarcoma is a malignant tumor that arises in fat cells in deep soft tissue, such as that inside the thigh or in the retroperitoneum. Liposarcoma is a rare type of cancer that bears a resemblance to fat cells when examined under a microscope. dedifferentiated liposarcoma has a poorly differentiated component, that is not identifiable as a liposarcoma (left edge of image), and a differentiated component with lipoblasts and increased vascularity (right of image).
Retroperitoneal liposarcoma is a sub type of liposarcoma, a malignant tumour of mesenchymal origin that may arise in any fat-containing region of the body.It is one of the most common primary retroperitoneal neoplasms 2. There are five histological types:1  well-differentiated: ~54%, low grade.2  lipoma-like.3  inflammatory.etroperitoneal liposarcoma is a sub type of liposarcoma, a malignant tumour of mesenchymal origin that may arise in any fat-containing region of the body.