K9 Advantix is for use on dogs and puppies 7 weeks of age and older only. It is used for the relevant prevention and treatment of fleas, mosquitoes and ticks including deer ticks (the major carrier of Lyme disease), American dog ticks, Brown dog ticks and lone star ticks.
Piplup is a Water-type PokÃ©mon that evolves into Prinplup at level 16, which evolves into Empoleon starting at level 36. It is one of the options for a trainer's starter PokÃ©mon. Shiny Piplup is on the left, normal Piplup on the right. Left: Prinplup Center: Piplup Right: Empoleon.
In familial forms of prion disease, PRNP gene mutations result in the production of an abnormally shaped protein, known as PrPSc, from one copy of the gene. In a process that is not fully understood, PrPSc can attach (bind) to the normal protein (PrPC) and promote its transformation into PrPSc.