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Vocal fold polyps (VFPs) are generally unilateral and have a broad spectrum of appearances, from hemorrhagic to edematous, pedunculated to sessile, and gelatinous to hyalinized. Vocal fold polyps (VFPs) are believed to result from phonotrauma; however, they are also recognized to potentially arise from a single episode of hemorrhage.
These two layers have poor differentiated boundary but are increasingly stiffer than SLLPs. The intermediate and deep layers of LPs compose the vocal ligaments which are enclosed within the vocal folds and are responsible for strain in phonation. Within the ECM community of vocal ligament, fibrous proteins such as elastin and collagen are pivotal in maintaining the proper elastic biomechanical property of vocal fold.