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Main symptom is pain in the abdomen, often on the right side. A blockage inside of the appendix causes appendicitis and can lead to increased pressure, problems with blood flow and inflammation. The appendix can become blocked by feces, a foreign object, or rarely, a tumor. If the blockage is not treated, the appendix can burst and spread infection into the abdomen.
For chronic adrenal insufficiency, the major contributors are autoimmune adrenalitis (Addison's Disease), tuberculosis, AIDS, and metastatic disease. Minor causes of chronic adrenal insufficiency are systemic amyloidosis, fungal infections, hemochromatosis, and sarcoidosis.