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Definition: A rhytid, (riâ²tid), is a wrinkle in the skin. The skin is composed of three layers: the epidermis, the dermis, and subcutaneous fat. The epidermis, the top layer of the skin, produces melanin, which gives the skin its color.
Thiazide diuretics. What are Thiazide diuretics. Thiazide diuretics are a type of diuretic (a drug that increases urine flow). They act directly on the kidneys and promote diuresis (urine flow) by inhibiting the sodium/chloride cotransporter located in the distal convoluted tubule of a nephron (the functional unit of a kidney).