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Submit. Â· just now. Report Abuse. The significance of the Human Genome project is to find out all of the genes in the Human DNA. Once scientist have found that out now they are using their new information to find out which genes cause which cancers and diseases and also for gene therapy. patricia Â· 9 years ago. Thumbs up.
It is considered a Mega Project because the human genome has approximately 3.3 billion base-pairs. With the sequence in hand, the next step was to identify the genetic variants that increase the risk for common diseases like cancer and diabetes.he project did not aim to sequence all the DNA found in human cells. It sequenced only euchromatic regions of the genome, which make up about 90% of the genome. The other regions, called heterochromatic are found in centromeres and telomeres, and were not sequenced under the project.