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Signs and symptoms of knee effusion include: 1  Puffiness and swelling in the knee. 2  Pain when bearing weight. 3  Stiffness or reduced range of motion due to increased fluid.  One knee appears noticeably larger than the 1  other. May feel warm to the touch.
Treat the cause of your knee effusion or excess fluid. Your doctor can remove the excess fluid in the knee through an aspiration procedure. The procedure also will relieve the pressure on your joint caused by fluid build-up. After the aspiration procedure, your doctor may inject corticosteroid into your knee joint.