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It uses a synthetic version of the hormone progesterone to achieve these results. Unlike the Pill, your physician will give you a shot, usually in the arm or buttocks. If Depo-Provera shots are received on a recommended basis, pregnancy is highly unlikely.
Depo âThe Shotâ. The Depo shot (DMPA) is a long acting progesterone contraceptive injection. This method of birth control is effective, convenient, and lasts three months. DMPA is safe even for women who can not take estrogen.It works by stopping ovulation and thickening cervical mucus which helps to prevent sperm from reaching the female egg.his method of birth control is effective, convenient, and lasts three months. DMPA is safe even for women who can not take estrogen. It works by stopping ovulation and thickening cervical mucus which helps to prevent sperm from reaching the female egg.