Calcium is required by two proteins, troponin and tropomyosin, that regulate muscle contraction by blocking the binding of myosin to filamentous actin. In a resting sarcomere, tropomyosin blocks the binding of myosin to actin.In the above analogy of pulling shelves, tropomyosin would get in the way of your hand as it tried to hold the actin rope. For myosin to bind actin, tropomyosin must rotate around the actin filaments to expose the myosin-binding sites.he contraction of myosin's S1 region is called the power stroke (Figure 3). The power stroke requires the hydrolysis of ATP, which breaks a high-energy phosphate bond to release energy.
Each round of hyaluronidase costs between $100-$200 for the enzyme injection, depending on how much is needed. It may require more than one session to achieve adequate filler dissolving. Adding any additional fillers would cost the regular prices of those syringes, on another day.
the science of clinically using hyaluronidase is still being worked out. How long it lasts is questionable. I would wait at least a week if not a month before injecting more filler to even it out. Otherwise, injecting the new filler in an area injected with hyaluronidase too soon, may produce more thinning than desired of the new filler.