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Definition: A rhytid, (riâ²tid), is a wrinkle in the skin. The skin is composed of three layers: the epidermis, the dermis, and subcutaneous fat. The epidermis, the top layer of the skin, produces melanin, which gives the skin its color.
See thiazide diuretics. /thiÂ·aÂ·zide/ (thiÂ´ah-zÄ«d) any of a group of diuretics that act by inhibiting the reabsorption of sodium in the proximal renal tubule and stimulating chloride excretion, with resultant increase in excretion of water.