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Hyperammonemia Hyperammonemia is a metabolic disturbance characterised by an excess of ammonia in the blood. It is a dangerous condition that may lead to encephalopathy and death.
HHH = hyperornithinemia-hyperammonemia-homocitrullinuria; MELAS = mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes. *â Inborn errors of metabolism can induce disease manifestations in any organ at various stages of life, from newborn to adulthood.