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The median nerve is one of the main nerves in the hand. It originates as a group of nerve roots in the neck. These roots come together to form a single nerve in the arm. The median nerve goes down the arm and forearm, passes through the carpal tunnel at the wrist, and goes into the hand. The nerve provides feeling in the thumb and index, middle, and ring fingers. The nerve also controls the muscles around the base of the thumb.
Carpal tunnel syndrome is a hand and arm condition that causes numbness, tingling and other symptoms. Carpal tunnel syndrome is caused by pressure on the median nerve in the carpal tunnel in your hand. The median nerve gives feeling to your thumb, and index, middle and ring fingers. When tissues in the carpal tunnel, such as ligaments and tendons, get swollen or inflamed, they press against the median nerve.