compensatory mechanisms are ineffective to maintain blood pressure & tissue perfusion. renin causes vasoconstriction & tissue hypoxia. brain & heart are protected by lipids being used as energy by the heart and glycogen transformed to glucose to be used by the brain.
A: The side effects of Effexor (venlafaxine) are similar to those of other antidepressants. Patients typically notice side effects when they're first starting Effexor, especially in the first two weeks of treatment. But they usually develop a tolerance for the drug, and the side effect symptoms improve.
It is recommended that a dose of 37.5 mg/day of prolonged-release venlafaxine be used for 7 days. Dosage should then be increased to 75 mg/day. Patients not responding to the 75 mg/day dose may benefit from dose increases up to a maximum dose of 225 mg/day.