Inferior vena cava. The inferior vena cava (or IVC) (Latin: vena, vein, cavus, hollow) is a large vein that carries deoxygenated blood from the lower and middle body into the right atrium of the heart. Its walls are rigid and has valves so the blood does not flow down via gravity.
Tight Junctions The tight junction (also referred to as a zonula occludens) is a site where the membranes of two cells come very close together. In fact, the outer leaflets of the membranes of the contacting cells appear to be fused. Tight junctions, as their name implies, act as a barrier so that materials cannot pass between two interacting cells.
Imagine a largely waterproof zipper connecting the sides of two different jackets. That zipper is like a tight junction (TJ), also called an occluding junction. A TJ creates a small zone that occludes the extracellular space (the space between cells). This is why tight junctions are also called zonula occludens.