Extinction _____. only happens above the species level cannot happen to more than one species at a time has happened to over 99% of species that ever lived on earth happens when a species or population dies out.
Nivolumab is also used to treat advanced renal cell carcinoma (RCC, a type of cancer that begins in the cells of the kidneys) that worsened after treatment with other chemotherapy medications. Nivolumab is in a class of medications called monoclonal antibodies.
Nivolumab binds PD-1 with high affinity (KD 2.6 nmol/l by Scatchard analysis to polyclonally activated human T cells) and blocks its interactions with both B7-H1 and B7-DC. It effectively inhibits the interaction between PD-1 and its ligands.