WHAT IS SIMULATION? Computer simulation is the discipline of designing a model of an actual or theoretical physical system, executing the model on a digital computer, and analyzing the execution output.
Efficacy is defined as the maximum effect a drug can produce, regardless of the dose. Potency is related to the amount of drug needed to produce a given effect; it is often quantified by the ED50 or EC50, which are respectively the drug dose or concentration that causes 50% of the maximum effect. Affinity is defined as a drug's ability to bind to a receptor.
Drug Substance Development In order to maximize your success in drug substance development, understanding of the active pharmaceutical ingredient (API) solid-form, its control in manufacturing, and consistent production is necessary.olymorphism is defined as the ability of a drug substance to exist as two or more crystalline phases that have different arrangements and /or conformations of the molecules in the crystal lattices [3]. Sometimes the properties of two solid forms of a drug are quite similar.