Approximately 30 motor freight companies serve the area. The Virginia Inland Port is located in Front Royal off Interstate 81, just 85 miles north of Waynesboro. The International Port Hampton Roads (185 miles) is the largest natural deep water harbor in the world.
The organic nitrates, including nitroglycerin, isosorbide dinitrate and isosorbide mononitrate, act as prodrugs for nitric oxide (NO) which is a potent vasodilator gas. Nitric oxide activates guanylyl-cyclase in vascular endothelial cells, which increases intracellular cyclic GMP and thereby reduces intracellular calcium concentrates and dephosphorylates myosin light chains causing relaxation of smooth muscle cells.
Calcium nitrate is used as a quick-release organic fertilizer that adds both calcium and nitrogen to soil. Quick-release fertilizer usually dissolves into the soil in four to six weeks. Slow-release fertilizers, typically coated with resin or sulfur, are available to plants over weeks or months.alcium nitrate is used as a quick-release organic fertilizer that adds both calcium and nitrogen to soil. Quick-release fertilizer usually dissolves into the soil in four to six weeks. Slow-release fertilizers, typically coated with resin or sulfur, are available to plants over weeks or months.