WHAT IS SIMULATION? Computer simulation is the discipline of designing a model of an actual or theoretical physical system, executing the model on a digital computer, and analyzing the execution output.
Efficacy is defined as the maximum effect a drug can produce, regardless of the dose. Potency is related to the amount of drug needed to produce a given effect; it is often quantified by the ED50 or EC50, which are respectively the drug dose or concentration that causes 50% of the maximum effect. Affinity is defined as a drug's ability to bind to a receptor.
Dose Intensification-Definition, Rationale, and Therapeutic Strategies. Dose intensity (DI) is a measure of the amount of drug delivered per unit of time, generally expressed as mg/m 2 /wk.Relative dose intensity (RDI) is the ratio of the delivered dose of a single drug (or of several drugs in a combination chemotherapy regimen) and the planned dose of the drug.It is calculated by dividing the DI of the administered regimen by the DI of the drug in the standard regimen.ose Intensification-Definition, Rationale, and Therapeutic Strategies. Dose intensity (DI) is a measure of the amount of drug delivered per unit of time, generally expressed as mg/m 2 /wk.