In the hepatic 17-ketosteroid pathway of testosterone metabolism, testosterone is converted in the liver by 5Î±-reductase and 5Î²-reductase into 5Î±-DHT and the inactive 5Î²-DHT, respectively. Then, 5Î±-DHT and 5Î²-DHT are converted by 3Î±-HSD into 3Î±,5Î±-androstanediol and 3Î±,5Î²-androstanediol, respectively.
Gardasil is approved for males ages 9 through 26 and Gardasil 9 is approved for use in males ages 9 through 15. The HPV vaccine does not treat or cure an HPV infection in women or men who are already infected by one of these HPV types.PV infection usually causes no symptoms, but can cause genital warts and anal cancer in both women and men. HPV can also cause throat cancer. In women, HPV infection can cause cells in the cervix to grow abnormally. In a small fraction of women, these HPV-induced changes will develop into cervical cancer.
In men, HPV can also cause cancer of the penis. HPV infection is found in about 6 out of 10 penile cancers. Itâs more common in men with HIV and those who have sex with other men. Thereâs no approved screening test to find early signs of penile cancer.here are vaccines that can be used to prevent infection with certain types of HPV. All HPV vaccines help prevent infections with HPV types 16 and 18. Some protect against other types, including types that can cause anal and genital warts.