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Cytosine (/ËsaÉªtÉËsiËn, -ËziËn, -ËsÉªn/;[2][3] C) is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA). It is a pyrimidine derivative, with a heterocyclic aromatic ring and two substituents attached (an amine group at position 4 and a keto group at position 2).
Cytosine is also a pyrimidine base. It binds to guanine in the DNA structure. Cytosine consists of oxygen, hydrogen, carbon and nitrogen. Like all pyrimidine bases, cytosine has a one-ring structure with six members. Cytosine, like thymine, can be converted to uracil in RNA, and cytosine is the most unstable of the four nucleotides. Because it is unstable, the bond between cytosine and guanine is the bond most easily broken within the DNA strand.