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Main symptom is pain in the abdomen, often on the right side. A blockage inside of the appendix causes appendicitis and can lead to increased pressure, problems with blood flow and inflammation. The appendix can become blocked by feces, a foreign object, or rarely, a tumor. If the blockage is not treated, the appendix can burst and spread infection into the abdomen.
Less common causes of primary adrenal insufficiency are chronic infections, mainly fungal infections; cancer cells spreading from other parts of the body to the adrenal glands; amyloidosis; and surgical removal of the adrenal glands. Each of these causes is discussed in more detail below. Secondary Adrenal Insufficiency. This form of Addisons disease can be traced to a lack of ACTH, which causes a drop in the adrenal glands production of cortisol but not aldosterone.