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proteome (plural proteomes) (biochemistry, genetics) The complete set of proteins encoded by a particular genome. [from 20th c.]
The term proteomics is a large-scale comprehensive study of a specific proteome, including information on protein abundances, their variations and modifications, along with their interacting partners and networks, in order to understand cellular processes. Proteins are dynamic. 2  Proteins are continually undergoing changes, e.g., binding to the cell membrane, partnering with other proteins to form complexes, or undergoing synthesis and degradation. 3  The genome, on the other hand, is relatively static. 4  Proteins are co-and post-translationally modified.