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Symptoms of primary coccidioidomycosis, in decreasing order of frequency, include fever, cough, chest pain, chills, sputum production, sore throat, and hemoptysis. Physical signs may be absent or limited to scattered rales with or without areas of dullness to percussion over lung fields.
The 4 main symptoms and signs are as follows: 1  Cutaneous mucosal symptoms - Glossitis, conjunctivitis, cheilosis. 2  CNS symptoms - Lethargy, decreased level of consciousness, anorexia, vomiting, seizures. 3  Ascending sensory polyneuropathy.  Anemia - Lymphopenia with eosinophilia.