According to the book of Exodus, it was treatment like this that caused Moses to kill an Egyptian and run away from Egypt. 15th Century B.C. Egyptian tomb fresco This fresco, or wall painting, is from a 15th century B.C. tomb in Egypt.
The most common sites of myocardial infarction are in the left ventricle, that chamber of the heart which has the greatest workload. Tissue changes that occur in the myocardium are related to the extent to which the cells have been deprived of oxygen.
The death of myocardial cells first occurs in the area of myocardium most distal to the arterial blood supply: the endocardium. As the duration of the occlusion increases, the area of myocardial cell death enlarges, extending from the endocardium to the myocardium and ultimately to the epicardium.