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Take pain medication. Taking an over-the-counter medication is one of the most effective ways to make cramps go away. Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and Tylenol work quickly to take away the pain. You can find them in most drug stores.
Thankfully, there are lots of ways you can stop the pain of a muscle cramp, and even stop them from occurring in the first place. These methods are almost entirely natural, and below youâll find a list of the top eight methods for soothing muscle pain and preventing any further involuntary contractions. 1. Ginger.