The system, to be established by the US Securities and Exchange Commission (SEC) and the North American Securities Administrators Association (NASAA)(1), will be based on technology used in the new Web-based Central Registration Depository (CRD) coming on line later this month.
Minivelle is currently the smallest estrogen patch available at 2.48cm 2 per patch (about 34% smaller than Vivelle-Dot). Minivelle contains bioidentical estradiol, a plant-based estrogen that is chemically identical to the estrogen produced naturally by a woman's body.
150 pg/mL is the guideline, if CTx is low, then discontinue the medication with physician approval and retest in 3 months. However, in random samples in the same patient, the value of CTx varied widely, so the accuracy of a sample may not be absolute. So this test is not an absolute necessity, just a guideline.