There are many reasons that a breast biopsy could be inconclusive. This could be because the amount of tissue that was obtained was not sufficient to reach a conclusion (for example, if you had a needle biopsy, this can sometimes happen).lternatively, it could be because the tissue had some abnormalities or irregularities in it that were of unclear significance. Your doctor will work closely with the pathologist who examined the biopsy sample and also potentially with a surgeon to determine what the next step is.
PRALUENT is to be used in the following two groups of patients: 1) patients with an inherited condition called heterozygous familial hypercholesterolemia (HeFH) or 2) patients who have had complications of having too much cholesterol, such as heart attacks and strokes.
The efficacy of PRALUENT was investigated in five double-blind, placebo-controlled trials that enrolled 3499 patients. Table 2 below summarizes the results for the primary efficacy endpoint, which was the mean percent change in LDL-C from baseline to week 24 for PRALUENT compared with placebo, for each trial.