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Thyroxine is the main hormone secreted into the bloodstream by the thyroid gland. It plays vital roles in digestion, heart and muscle function, brain development and maintenance of bones. Alternative names for thyroxine T4; tetraiodothyronine; thyroxin.
1 Low levels of T4 produce hypothyroidism, and high levels produce hyperthyroidism. 2  Thyroxine converts to triiodothyronine (T3), which is a more biologically active hormone. 3  Only about 20% of triiodothyronine is actually formed in the thyroid gland. Thyroxine (T4) and Triiodothyronine (T3) . 2  Thyroxine (T4) is the key hormone produced in the thyroid gland. 3  Low levels of T4 produce hypothyroidism, and high levels produce hyperthyroidism. 4  Thyroxine converts to triiodothyronine (T3), which is a more biologically active hormone.