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Take Synthroid with water only on an empty stomach. Take Synthroid 4 hours before or after. taking iron or calcium supplements, or antacids. Soy, cottonseed meal, walnuts, fiber, and. grapefuit juice can affect the absorption of Synthroid.
When you start taking Synthroid, itâs very important for the doctor to monitor you closely. Your Synthroid dose may need to be adjusted over the course of several weeks before the doctor finds the dose thatâs right for you. Throughout your lifetime, the doctor may also need to adjust your dosage. This is because the amount of thyroid hormone you need may change over time or with major life changes such as pregnancy and menopause. NEXT: Side effects of Synthroid.