Nicotinic receptor activation causes the opening of the channel formed by the receptor. This increases the Na+ movement into the target cell, leading to depolarization and generation of the action potential. This rapidly developing change, termed a fast EPSP, is illustrated in Figures 4.3, and 6.2.
Just like red pepper, black pepper has a thermogenic effect when ingested. The spice stimulates your metabolism and thus temporarily increases body heat. A higher basal metabolic rate means higher energy expenditure or more calories burned.
Story at-a-glance 1  +. The spicy chemical in peppers â capsaicin â and other compounds in spicy food can improve your health. 2  Capsaicin has been shown to activate cell receptors in your intestinal lining, creating a reaction that lowers the risk of tumors.