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Take pain medication. Taking an over-the-counter medication is one of the most effective ways to make cramps go away. Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and Tylenol work quickly to take away the pain. You can find them in most drug stores.
Foot cramps are not only painful and annoying, but they can interfere with your sleep, which in turn has a negative effect on your entire health. Among the things that you can do to help combat foot cramps is to increase your intake of certain vitamins or take over-the-counter supplements. Vitamin B-12, also known as cobalamin, is one substance that may help with the cramping; however, check with your doctor before adding it to your diet.