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3 doctors weighed in: When during pregnancy should you stop laying on your back? 3 doctors weighed in Want a second opinion? At approximately 24 weeks you should avoid laying on your back for prolonged periods of time in order to avoid compression of veins (vena cava). In brief: 6 months.
Most people change positions quite often during their sleep and it's highly unlikely you'd spend the whole night sleeping on your back. Also, during the third trimester, the majority of women awaken two or three times during the night to use the restroom. This means you're not spending enough time sleeping on your back to cause any risk. If you must sleep on your back, however, it's best to place a pillow under your knees.