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The sciatic nerve is the longest and largest nerve in the body; it measures three-quarters of an inch in diameter. It originates in the sacral plexus; a network of nerves in the low back (lumbosacral spine). The lumbosacral spine refers to the lumbar spine and the sacrum combined.he sciatic nerve starts in your low back, which is called your lumbar spine. The nerve roots are at the L4 and L5 vertebrae (the 'L' means lumbar, and the numbers indicate the level of the vertebraâwhere it is in your back). The sciatic nerve also travels through your pelvic region (sacrum).
The sciatic nerve forms from the merger of the fourth and fifth lumbar nerves with the first, second, and third sacral nerves.... Click to read more below. The sciatic nerve is the largest and longest spinal nerve in the human body.Extending from the lumbar and sacral plexuses in the lower back, the sciatic nerve runs through the buttocks and into the thighs. It delivers nerve signals to and from the muscles and skin of the thighs, lower legs and feet.he sciatic nerve forms from the merger of the fourth and fifth lumbar nerves with the first, second, and third sacral nerves.... Click to read more below. The sciatic nerve is the largest and longest spinal nerve in the human body.