Nicotinic receptor activation causes the opening of the channel formed by the receptor. This increases the Na+ movement into the target cell, leading to depolarization and generation of the action potential. This rapidly developing change, termed a fast EPSP, is illustrated in Figures 4.3, and 6.2.
And, anecdotally at least, they act as an overall stimulant, producing a titillating, awakening effect and increasing the acuity of the senses. Peppers, especially the hot capsicum (chili) peppers, produce a burning sensation on the skin and mucous membranes, including the inside of the mouth. For the uninitiated, a relatively mild hot pepper can seem intolerably strong and truly hot peppers may even cause blistering of the lips and palate.
Hot Peppers. Hot peppers, Capsicum annuum, also called chili peppers, are toxic. Chili peppers are commonly used in the garden and the kitchen for their hot, spicy flavor. The hot flavor is actually a result of the mildly poisonous nature of the plant.The leaves and fruits of chili peppers are toxic when touched and eaten. The burning sensation you get when you handle or eat hot peppers is the toxicity of the plant.When large quantities of pepper are consumed, you will feel a burning of the throat, tongue, eyes and skin.he hot flavor is actually a result of the mildly poisonous nature of the plant. The leaves and fruits of chili peppers are toxic when touched and eaten. The burning sensation you get when you handle or eat hot peppers is the toxicity of the plant.