Nicotinic receptor activation causes the opening of the channel formed by the receptor. This increases the Na+ movement into the target cell, leading to depolarization and generation of the action potential. This rapidly developing change, termed a fast EPSP, is illustrated in Figures 4.3, and 6.2.
Just like red pepper, black pepper has a thermogenic effect when ingested. The spice stimulates your metabolism and thus temporarily increases body heat. A higher basal metabolic rate means higher energy expenditure or more calories burned.
Mupirocin Adverse Effects. The most common side effect of topical mupirocin treatment is mild skin irritation. In rare cases, patients may experience more serious skin irritations. Topically applied mupirocin is poorly absorbed into the blood stream and systemic reactions are rare.