The field is familiar with the five conditions of collective impact, but what are the... Update: The Spanish-language version of this article, Encauzamiento del cambio: cÃ³mo lograr que el impacto colectivo funcione, is now added to this page for download.
The tetanus toxin affects the site of interaction between the nerve and the muscle that it stimulates.This region is called the neuromuscular junction.The tetanus toxin amplifies the chemical signal from the nerve to the muscle, which causes the muscles to tighten up in a continuous (tetanic or tonic) contraction or spasm.This results in either localized or generalized muscle spasms.he tetanus toxin amplifies the chemical signal from the nerve to the muscle, which causes the muscles to tighten up in a continuous (tetanic or tonic) contraction or spasm. This results in either localized or generalized muscle spasms.
Muscles will contract or relax when they receive signals from the nervous system. The neuromuscular junction is the site of the signal exchange. The steps of this process in vertebrates occur as follows:(`) The action potential reaches the axon terminal.(2) Voltage-dependent calcium gates open, allowing calcium to enter the axon terminal.he neuromuscular junction is where a neuron activates a muscle to contract. Upon the arrival of an action potential at the presynaptic neuron terminal, voltage-dependent calcium channels open and Ca 2+ ions flow from the extracellular fluid into the presynaptic neuron's cytosol.