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Take pain medication. Taking an over-the-counter medication is one of the most effective ways to make cramps go away. Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and Tylenol work quickly to take away the pain. You can find them in most drug stores.
How Can You Get Rid of Menstrual Cramps? If you are one of the unlucky ones who gets cramps, here are some tips to ease the pain: Heat: With your first line of defense, you can apply a heating pad to the cramping areas of your stomach. For some women, that is enough.