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A Bakerâs cyst is also known as a popliteal cyst or synovial cyst. It is a soft, fluid-filled lump that forms on the back of the knee. The lump is sometimes mistaken for a blood clot, but it is not a blood clot.A Bakerâs cyst usually develops because of damage to the knee. Bakerâs cyst is also known as a popliteal cyst or synovial cyst. It is a soft, fluid-filled lump that forms on the back of the knee. The lump is sometimes mistaken for a blood clot, but it is not a blood clot.
Pilonidal (say py-luh-NY-dul) disease is a chronic skin infection in the crease between the buttocks. People with this condition have one or more cysts in that area that tend to get inflamed and infected. A pilonidal cyst may look like a small dimple (called a pit or sinus).xperts think pilonidal cysts may form in one of three ways: 1  A hair follicle in the skin becomes irritated or stretched. 2  A loose hair may get trapped in the crease between the buttocks. 3  Some cysts may be present at birth (congenital).