The cause of irritable bowel syndrome is unknown. Antibiotic-associated colitis usually occurs in people receiving antibiotics. Inflammatory bowel diseases is a common cause of bowel inflammation and low back pain. There are two major forms: Crohns disease and ulcerative colitis. The causes are unknown. â¢Genetic: There is a high similarity of symptoms among identical twins, particularly with Crohn disease.
An effective dose (ED) in pharmacology is the dose or amount of drug that produces a therapeutic response or desired effect in some fraction of the subjects taking it.D50 [edit]. The median effective dose is the dose that produces a quantal effect (all or nothing) in 50% of the population that takes it (median referring to the 50% population base). It is also sometimes abbreviated as the ED50, meaning effective dose, for 50% of people receiving the drug.
Almost 20 years ago, Emami et al. presented a comprehensive set of dose tolerance limits for normal tissue organs to therapeutic radiation, which has proven essential to the field of radiation oncology.t must be noted that dose tolerance limits and dose-volume histogram (DVH) analysis only show part of the overall situation. The location where the high dose occurred could sometimes be more important than how high the dose is.