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Take Synthroid with water only on an empty stomach. Take Synthroid 4 hours before or after. taking iron or calcium supplements, or antacids. Soy, cottonseed meal, walnuts, fiber, and. grapefuit juice can affect the absorption of Synthroid.
I have been on synthroid since I was 18, and at the age of 38, had most of my thyroid removed. I used to know every restroom, on any given route I used, from Virginia, to Florida. I found the drug, 'Lomotil, somewhere, and asked my doc for a script. He was really stingy with it.