Nicotinic receptor activation causes the opening of the channel formed by the receptor. This increases the Na+ movement into the target cell, leading to depolarization and generation of the action potential. This rapidly developing change, termed a fast EPSP, is illustrated in Figures 4.3, and 6.2.
Just like red pepper, black pepper has a thermogenic effect when ingested. The spice stimulates your metabolism and thus temporarily increases body heat. A higher basal metabolic rate means higher energy expenditure or more calories burned.
Best Answer: I would not wish you to contradict your elder relatives. Pepper is a spice I cannot digest dur to diverticular disease. I believe were it to settle, it would be in the appendix. In my case, it aggravates the intestinal tract. My father peppered his food more than anyone, but suffered no ill effects. Should you wish to research further, check human digestive system.