The field is familiar with the five conditions of collective impact, but what are the... Update: The Spanish-language version of this article, Encauzamiento del cambio: cÃ³mo lograr que el impacto colectivo funcione, is now added to this page for download.
The tetanus toxin affects the site of interaction between the nerve and the muscle that it stimulates.This region is called the neuromuscular junction.The tetanus toxin amplifies the chemical signal from the nerve to the muscle, which causes the muscles to tighten up in a continuous (tetanic or tonic) contraction or spasm.This results in either localized or generalized muscle spasms.he tetanus toxin amplifies the chemical signal from the nerve to the muscle, which causes the muscles to tighten up in a continuous (tetanic or tonic) contraction or spasm. This results in either localized or generalized muscle spasms.
A neuromuscular junction is a chemical synapse formed by the contact between a motor neuron and a muscle fiber. It is at the neuromuscular junction that a motor neuron is able to transmit a signal to the muscle fiber, causing muscle contraction. Muscles require innervation to functionâand even just to maintain muscle tone, avoiding atrophy. Synaptic transmission at the neuromuscular junction begins when an action potential reaches the presynaptic terminal of a motor neuron, which activates ...