The field is familiar with the five conditions of collective impact, but what are the... Update: The Spanish-language version of this article, Encauzamiento del cambio: cÃ³mo lograr que el impacto colectivo funcione, is now added to this page for download.
The tetanus toxin affects the site of interaction between the nerve and the muscle that it stimulates.This region is called the neuromuscular junction.The tetanus toxin amplifies the chemical signal from the nerve to the muscle, which causes the muscles to tighten up in a continuous (tetanic or tonic) contraction or spasm.This results in either localized or generalized muscle spasms.he tetanus toxin amplifies the chemical signal from the nerve to the muscle, which causes the muscles to tighten up in a continuous (tetanic or tonic) contraction or spasm. This results in either localized or generalized muscle spasms.
A neuromuscular disease is a disorder that affects the peripheral nervous system.The peripheral nervous system includes muscles, the nerve-muscle (neuromuscular) junction, peripheral nerves in the limbs, and the motor-nerve cells in the spinal cord.Other spinal cord or brain diseases are not considered âneuromuscularâ diseases.Patients with neuromuscular diseases can have weakness, loss of muscle bulk, muscle twitching, cramping, numbness, tingling, and a host of other symptoms.Problems with the nerve-muscle junction can also cause droopy eyelids, double vision, and weakness that worsen with activity.ther spinal cord or brain diseases are not considered âneuromuscularâ diseases. Patients with neuromuscular diseases can have weakness, loss of muscle bulk, muscle twitching, cramping, numbness, tingling, and a host of other symptoms.