Chase Nipple, 1/2 Inch, Material: Zinc Die Cast, For Use With a Conduit Coupling to Connect Conduit to a Box, or With a Locknut to Connect Two Boxes
The effect of acetylcholine depletion on behavior following traumatic brain injury. Robinson SE, Martin RM, Davis TR, Gyenes CA, Ryland JE, Enters EK.hese results confirm cholinergic involvement in the production of both transient and longer-lasting behavioral deficits following traumatic brain injury. Furthermore, traumatic brain injury may allow plasma constituents to gain access to the central nervous system.
Acetylcholine is released from a presynaptic neuron into the synaptic cleft. Once in the synaptic gap, acetylcholine can: - Bind to presynaptic receptors: presynaptic activation or inhibition leads to automodulation of the presynaptic cholinergic neuron.- Be degradated by acetylcholinesterase: activity of this enzime on acetylcholine triggers its degradation into choline and acetyl coenzime A, thus terminating its effect. number of drugs target acetylcholine receptors, blockade of these receptors is associated with anticholinergic (parasympatholytic) effect, while stimulation causes activation of cholinergic (parasympathomimetic) effects. This articles overviews the key concepts on the pharmacology of acetylcholine receptors, such as: