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Skin, mouth, genital symptoms â One characteristic feature of acute HIV infection is open sores or ulcers. These sores or ulcers can develop in the mouth, the esophagus (the tube that extends from the mouth to the stomach), the anus, or the penis. The ulcers are usually painful.
Signs and Symptoms. HIV initially causes an acute illness with non-specific, flu-like symptoms such as fever, fatigue, headache, sore throat, rash, and enlarged lymph nodes. Some people do not experience any noticeable symptoms. In most people, the initial symptoms go away after a few weeks.