In humans (n = 10) infused with 1.0â1.3 mmol sodium dl-lactate/(kg Â· h), â¼90% of d-lactate was metabolized, and 10% excreted in the urine (12). At higher infusion rates of 3.0â4.6 mmol/(kg Â· h), metabolism decreased to â¼75% of overall clearance (12).
Deaths from alcohol poisoning as a contributing cause peaked for those between ages 35 and 44 (average age at death was 39.9 years). When the age-specific rate was calculated using deaths with any mention of alcohol poisoning, the rate was highest at ages 35 to 44 (1.33 deaths per 100,000 population).
That trend has only strengthened, with poisoning now the major cause of unintentional fatal injuries among working-age adults aged 25 to 64. In 18 states and Washington, D.C., poisoning is the leading cause of accidental death. Drugs both legal and illicit accounted for nearly 91 percent of poisoning deaths reported in 2010, the report found, with alcohol poisoning accounting for an additional 6 percent.