Akt Signaling. Akt (v-Akt Murine Thymoma Viral Oncogene)/ PKB (Protein Kinase-B) is a Serine/threonine Kinase that is involved in mediating various biological responses, such as inhibition of Apoptosis and stimulation of cell proliferation. Three mammalian isoforms are currently known: Akt1/PKB- Alpha, Akt2/PKB-Beta and Akt3/PKB-Gamma.
Vascular: Relating to blood vessels. For example, the vascular system in the body includes all of the veins and arteries. And, a vascular surgeon is an expert at evaluating and treating problems of the veins and arteries.
Vascular dementia is a term for dementia associated with problems in the circulation of blood to the brain (cerebrovascular disease). It encompasses a wide range of diseases or disorders, the principal feature of which is loss of intellectual abilities. Binswanger's Disease Binswangerâs Disease is a subcortical vascular dementia which was once considered rare but is now being reassessed, and may be relatively common.