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SIDE EFFECTS: Nausea, tiredness, flu-like symptoms (e.g., fever, chills, muscle/joint aches), dizziness, headache, or pain/redness/swelling at the injection site may occur. Most of these side effects are mild and occur within 3 days of treatment.
Cortisone Injection Side Effects. Both localized atrophy of the subcutaneous tissues and discoloration are well known side effects of cortisone injections. Sometimes these are the desired effects of the injection, as when we inject steroids around nerve entrapments, with the intent that the atrophy will decrease the pressure on the nerve.