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Assessment of Depression in Advanced Illness. What Symptoms to Look for and How to Assess. Somatic symptoms (e.g., changes in appetite, weight, energy level, libido, or sleeping) are almost invariably present in patients with advanced illness.
The scale was administered to 259 patients, with the results indicating that the assessment tool was a useful measurement for further study of uncertainty in illness (Mishel, 1981). Mishel continued to research uncertainty, publishing multiple papers on the theory as applied to patients with cancer.