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What Does Extended Release Mean in Medications? Over-the-counter pills come in many formulas, such as time release, controlled release, extended release, delayed release or sustained release. How does time release work, and what are the advantages and disadvantages to it? What should you know before choosing a standard or time release formula?
Use of Niacin extended-release tablets in patients with renal or hepatic impairment has not been studied. Niacin extended-release tablets is contraindicated in patients with significant or unexplained hepatic dysfunction. Niacin extended-release tablets should be used with caution in patients with renal impairment [see Warnings and Precautions (5)].