In humans (n = 10) infused with 1.0â1.3 mmol sodium dl-lactate/(kg Â· h), â¼90% of d-lactate was metabolized, and 10% excreted in the urine (12). At higher infusion rates of 3.0â4.6 mmol/(kg Â· h), metabolism decreased to â¼75% of overall clearance (12).
Deaths from alcohol poisoning as a contributing cause peaked for those between ages 35 and 44 (average age at death was 39.9 years). When the age-specific rate was calculated using deaths with any mention of alcohol poisoning, the rate was highest at ages 35 to 44 (1.33 deaths per 100,000 population).
Nearly 4% of all deaths are related to alcohol. Most alcohol-related deaths are caused by alcohol result from injuries, cancer, cardiovascular diseases and liver cirrhosis. 6.2% of male deaths are related to alcohol, compared to 1.1% of female deaths. 320 000 young people aged 15-29 years die annually, from alcohol-related causes, resulting in 9% of all deaths in that age group. Almost 50% of men and two-thirds of women do not consume alcohol.