Ras Pathway. Ras is a membrane-associated guanine nucleotide-binding protein that is normally activated in response to the binding of extracellular signals, such as growth factors, RTKs (Receptor Tyrosine Kinases), TCR (T-Cell Receptors) and PMA (Phorbol-12 Myristate-13 Acetate).
Sicily Description. Sicily is Italy's largest island and the largest island in theMediterranean Sea. It's also a geographical and political region of Italy, famed for its beautiful beaches, cuisine, and fascinating history.
History of Sicily and the Origins of the Mafia. Like the entomology of the word 'mafia', the history of Sicily and its relationship with the Mafia is very eclectic. Because of its geographic location, Sicily is a desirable location for trade and colonization.