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Equally important and coupled with DNA methylation is DNA demethylation, the removal of a methyl group. The demethylation process is necessary for epigenetic reprogramming of genes and is also directly involved in many important disease mechanisms such as tumor progression.
DNA Ligase Defined. DNA ligase is an enzyme that has a very critical role in the process of DNA replication and DNA repair. There are two different things going on when DNA is replicated. Let's revisit this process very briefly.