The great white shark is notable for its size, with mature female individuals growing up to 6.1 m (20 ft) in length and 1,950 kg (4,300 lb) in weight. However most are smaller, males measuring 3.35 to 3.96 m (11 ft 0 in to 13 ft 0 in) and females 4.57 to 4.88 m (15 ft 0 in to 16 ft 0 in) on average.
For most ALS genes, only one mutated copy is needed to cause disease. This is called a âdominantâ gene. For other genes, both copies must be mutated to cause disease. This is called a ârecessiveâ gene. During formation of eggs and sperm, gene pairs split up, so that an egg (or sperm) contains only one gene copy.
The cancer risk caused by BRCA1 and BRCA2 mutations are inherited in a dominant fashion even though usually only one mutated allele is directly inherited. This is because people with the mutation are likely to acquire a second mutation, leading to dominant expression of the cancer.