Gothic fiction, which is largely known by the subgenre of Gothic horror, is a genre or mode of literature that combines fiction, horror, death and Romanticism.ts origin is attributed to English author Horace Walpole, with his 1764 novel The Castle of Otranto, subtitled (in its second edition) A Gothic Story.. The effect of Gothic fiction feeds on a pleasing sort of terror, an extension of Romantic literary pleasures that were relatively new at the time of Walpole's novel.
The pituitary gland, a small gland at the base of the brain, makes and secretes a hormone known as adrenocorticotropic hormone, or ACTH. Secretion of ACTH signals the adrenal glands to increase cortisol production and secretion.The pituitary, in turn, receives signals from the hypothalamus of the brain in the form of the hormone CRH, or corticotrophin-releasing hormone, which signals the pituitary to release ACTH.he marker used to measure stress is the adrenal steroid hormone, cortisol. Stress, whether physical or emotional in origin, provokes a response by the adrenal glands. Many hormonal imbalances are the direct result of adrenal insufficiency. The adrenal glands produce two primary hormones, DHEA and cortisol.
The adrenal gland has a center gland (medulla) that produces adrenaline and an outer gland (the cortex) that produces several hormones, such as cortisol an aldosterone. This page is about cortisol overproduction by the adrenal cortex.Causes of Cushing's Syndrome.t is now known that these symptoms characterize Cushing's syndrome, which is the result of excess production of cortisol by the adrenal glands. Cortisol is a powerful steroid hormone, and excess cortisol has detrimental effects on many cells throughout the body.