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The pericardium (from the Greek ÏÎµÏÎ¯, around and ÎºÎ¬ÏÎ´Î¹Î¿Î½, heart) is a double-walled sac containing the heart and the roots of the great vessels. The pericardial sac has two layers, a serous layer and a fibrous layer. It encloses the pericardial cavity which contains pericardial fluid. The pericardium fixes the heart to the mediastinum, gives protection against infection, and provides the lubrication for the heart.
1 The following is true concerning the endocardium. 2  the endocardium can also be called the pericardial sac. 3  the endocardium lines the inner surface of the sac that surrounds the heart.  the endocardium is a two-layered structure: the parietal and visceral layers.