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The pericardium (from the Greek ÏÎµÏÎ¯, around and ÎºÎ¬ÏÎ´Î¹Î¿Î½, heart) is a double-walled sac containing the heart and the roots of the great vessels. The pericardial sac has two layers, a serous layer and a fibrous layer. It encloses the pericardial cavity which contains pericardial fluid. The pericardium fixes the heart to the mediastinum, gives protection against infection, and provides the lubrication for the heart.
The fibroserous sac enclosing the heart and the roots of the great vessels, consisting of two layers: the visceral layer or epicardium, immediately surrounding the heart; and the outer parietal layer, which forms the sac and is lined with a serous membrane. Also called heart sac, theca cordis.arietal pericardium. the parietal layer of the serous pericardium, which is in contact with the fibrous pericardium. serous pericardium. the inner, serous portion of pericardium, consisting of two layers, visceral and parietal; the space between the layers is the pericardial cavity.