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1 Artificial Sweeteners Artificial sweeteners and sugar alcohols, particularly mannitol and sorbitol, can cause diarrhea in some people. 2  Mannitol and sorbitol linger in the stomach, Schiller says, which can result in bloating and diarrhea.
In fact, âaspartame depressionâ has long been cited as one of the results of consuming this artificial sweetener, along with other side effects such as migraines, seizures and memory loss.