Per general etiquette, the mother of the bride buys her wedding day outfit first, then notifies the mother of the groom about the color, length and overall formality of her choice. But if the groom's mom doesn't get word by the four-month mark, she should touch base with the bride-to-be about what to do.
Genetics. The two main types of hemophilia are caused by gene mutations that affect the levels of clotting factors in the blood. Mutation of the FVIII gene leads to hemophilia A, also called classic hemophilia, while a mutations in the FIX gene leads to hemophilia B, also called Christmas disease.
Patients with Hemophilia B have a defect in their Factor IX gene, such as deletions of variable length or point mutations. Patients with mild hemophilia maintain low levels of the clotting factor (5%-40% of the normal level in blood).To treat patents with mild hemophilia, gene therapy. Currently, patients with severe hemophilia can be administered recombinant, or artificial, clotting factor at defined intervals as a preventative measure.atients with Hemophilia B have a defect in their Factor IX gene, such as deletions of variable length or point mutations. Patients with mild hemophilia maintain low levels of the clotting factor (5%-40% of the normal level in blood). To treat patents with mild hemophilia, gene therapy.