Ras Pathway. Ras is a membrane-associated guanine nucleotide-binding protein that is normally activated in response to the binding of extracellular signals, such as growth factors, RTKs (Receptor Tyrosine Kinases), TCR (T-Cell Receptors) and PMA (Phorbol-12 Myristate-13 Acetate).
Sicily Description. Sicily is Italy's largest island and the largest island in theMediterranean Sea. It's also a geographical and political region of Italy, famed for its beautiful beaches, cuisine, and fascinating history.
By the time the Greeks were colonizing Syracuse and the rest of Sicily, the Phoenicians were already (9th century B.C.) a major power in the middle of the Mediterranean. The principal city of the Phoenicians, Carthage, was located near modern Tunis, on a promontory on the Northern Coast of Africa.