In summary, the relative refractory period is a time in which the neuron can fire an action potential, but it needs a greater stimulus. During an action potential, voltage-gated sodium channels open to let in positive ions - sodium. These depolarize the cell.
On average, reciting five Mysteries of the Rosary typically takes about 15-20 minutes depending on whether the optional prayers are also recited. Additionally, some people may take longer than 20 minutes if they decide to devote extra time for reflection and meditation on any of the Mysteries.
The particular manner in which we now pray the Rosary was brought into vogue by St. Dominic. This is attested by the tradition of six centuries. Twelve Popes bear witness to this fact. We will now speak of the introduction by St. Dominic, and will also refer to the great efficacy of this devotion since its inception.