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When Milan was the capital of the west, it surpassed Rome in importance because the imperial court was there. Christianity was made the state religion of the empire with the Edict of Milan. Two fathers of the Catholic church worked in Milan.
The Cathedral of St. Peter in Chain's is also important as the location of the final resting place of former religious leaders of the church. In the early 1980's, a crypt was discovered under the church. Given the date of the burials, it was most likely constructed at the time of the original frame church at this site.