Periodontal Ehlers-Danlos syndrome Periodontal EDS (pEDS) causes dental problems, particularly inflamed or absent gums and poor tooth development, on top of typical features of cEDS. It is rare but can be inherited from one parent only, as only one faulty gene is needed to develop the condition.
Ribs 1, 2, 11 and 12 can be describes as âatypicalâ â they have features that are not common to all the ribs. Rib 1 is shorter and wider than the other ribs. It only has one facet on its head for articulation with its corresponding vertebrae (there isnât a thoracic vertebrae above it).
Collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital) , also known as COL2A1, is a human gene that provides instructions for the production of the pro-alpha1(II) chain of type II collagen. Stickler syndrome: Several of the mutations in the COL2A1 gene result in the production of an abnormally short protein that cannot be incorporated into a type II collagen fiber. 2  Most of the mutations in COL2A1 that cause Stickler syndrome, however, have a premature stop signal in one copy of the gene.