Leroy Satchel Paige was the longtime Negro League star who eventually received his due in the majors. He reportedly got his nickname working as a baggage porter in Mobile, Ala., where he became a satchel tree by carrying several bags at once. Satchel, the man, was literally ageless.
The diagnosis of AML requires the identification of 20% or more leukemic blasts in the bone marrow. Further analysis then must separate AML from acute lymphoblastic leukemia by showing evidence for commitment to the myeloid lineage.
Acute myeloid leukemia (AML) is a heterogeneous disease characterized by recurrent genetic aberrations. At present, survival rates in pediatric AML are approximately 60â70%. The most important factors predicting clinical outcome are genetic and molecular aberrations, and early response to treatment.