Appendicitis is when the appendix becomes inflamed, often because of a blockage within it. The blockage causes the appendix to swell and it can easily become infected by bacteria. In many children the exact cause is not obvious, even at operation.
The worldwide pioneer in the creation of interactive entertainment, Nintendo Co., Ltd., of Kyoto, Japan, manufactures and markets hardware and software for its Wii Uâ¢ and Wiiâ¢ home consoles, Nintendo 3DSâ¢ and Nintendo DSâ¢ family of portable systems.
As of 31 March 2014, Nintendo has cumulative sales of over 670.43 million hardware units and 4.23 billion software units. The company has created some of the most well known and best-selling video game franchises in the industry, such as Mario, The Legend of Zelda, and Metroid, while also owning The PokÃ©mon Company.