Ionized calcium binds to negatively charged sites on protein molecules, competing with hydrogen ions for the same binding sites on albumin and other calcium-binding proteins.This binding is pH dependent and alters the level of ionized calcium in the blood.An increase in pH, alkalosis, promotes increased protein binding, which decreases free calcium levels.onized calcium is interpreted in conjunction with the total serum calcium measurement. An ionized calcium value within the reference range implies adequate calcium homeostasis, as this is a direct measure of calcium in its active form.
For other uses, see Manifesto (disambiguation). A manifesto is a published verbal declaration of the intentions, motives, or views of the issuer, be it an individual, group, political party or government. A manifesto usually accepts a previously published opinion or public consensus or promotes a new idea with prescriptive notions for carrying out changes the author believes should be made.
preÂ·view. n. 1. An advance showing, as of a movie or art exhibition, to which a selected audience is invited before public presentation begins. 2. also preÂ·vue An advance viewing or exhibition, especially the presentation of several scenes advertising a forthcoming movie; a trailer.