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When Milan was the capital of the west, it surpassed Rome in importance because the imperial court was there. Christianity was made the state religion of the empire with the Edict of Milan. Two fathers of the Catholic church worked in Milan.
Constantinople is a city founded, and named after, Constantine the Great as a second capital of the Roman Empire. After the division of the Roman Empire, Constantinople became the capital of the Byzantine Empire.yzantine Mosaic of Emperor Constantine I and the Hagia Sophia. Constantine I was declared Roman Emperor in 306 AD, but officially held the office from 324 until his death in 337 AD. He change the city's former name, Byzantium to Constantinople, the City of Constantine, on November 26th 326 AD.