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The 153 in the treatment group were also given monthly injections of extended-release naltrexone, a non-narcotic opioid antagonist that works by blocking opioid receptors. Heroin or any other opioid would have no effect while the person is using the blocker medication, sold under the brand name Vivitrol.
1 A long-acting (extended-release) opioid pain medicine that can put you at risk for overdose and death. 2  Even if you take your dose correctly as prescribed you are at risk for opioid addiction, abuse, and misuse that can lead to death. 3  Not for use to treat pain that is not around-the-clock. A long-acting (extended-release) opioid pain medicine that can put you at risk for overdose and death. 2  Even if you take your dose correctly as prescribed you are at risk for opioid addiction, abuse, and misuse that can lead to death. 3  Not for use to treat pain that is not around-the-clock.