Periodontal Ehlers-Danlos syndrome Periodontal EDS (pEDS) causes dental problems, particularly inflamed or absent gums and poor tooth development, on top of typical features of cEDS. It is rare but can be inherited from one parent only, as only one faulty gene is needed to develop the condition.
Ribs 1, 2, 11 and 12 can be describes as âatypicalâ â they have features that are not common to all the ribs. Rib 1 is shorter and wider than the other ribs. It only has one facet on its head for articulation with its corresponding vertebrae (there isnât a thoracic vertebrae above it).
Three variants are known to exist, FAP and attenuated FAP (originally called âhereditary flat adenoma syndrome) are caused by APC gene defects and autosomal recessive FAP (or MYH-associated polyposis) is caused by MUTYH gene defects.nternational polyposis registries exists that track known cases of FAP or APC gene defects, for research and clinical purposes. Mutation of APC also occurs commonly in incident cases of colorectal carcinoma, emphasizing its importance in this form of cancer.