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1 Artificial Sweeteners Artificial sweeteners and sugar alcohols, particularly mannitol and sorbitol, can cause diarrhea in some people. 2  Mannitol and sorbitol linger in the stomach, Schiller says, which can result in bloating and diarrhea.
The artificial sweetener perhaps most associated with digestive problems is sorbitol. It's a hard-to-digest sugar found naturally in some fruits, including prunes, apples, and peaches, and is also used to sweeten gum and diet foods. Once sorbitol reaches the large intestine, it often creates gas, bloating, and diarrhea.