Bismuth subsalicylate may cause ringing in the ears, but that side effect is rare. Possible side effects from loperamide include skin rash, constipation, drowsiness, dizziness, tiredness, dry mouth, nausea, vomiting, and swelling, pain, and discomfort in the abdomen.
In the United States, the annual cost of soil erosion for both on-site and off-site effects has been estimated at 44 billion dollars a year (Pimentel et al., 1995). In the European Union, the figure is 38 billion Euros a year (Montanarella, 2007).
1 Soils, even at organic farms, become depleted of vitamins and minerals after years of cultivation.  Soils are much more depleted than they were even 30 years ago as pesticide use and chemical fertilizers, contributing to soil depletion, have increased in use over the years.