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Cowden syndrome is a disorder characterized by multiple noncancerous, tumor-like growths called hamartomas and an increased risk of developing certain cancers. Almost everyone with Cowden syndrome develops hamartomas.
NUTRITIONAL CNS DISORDERS. The Wernicke-Korsakoff syndrome (WKS) is a combination of oculomotor abnormalities and mental symptoms seen in malnourished patients with vitamin B1 (thiamine) deficiency.he topography of the lesions in the WKS resembles the Leigh syndrome, a metabolic disorder caused by defects of the pyruvate dehydrogenase complex and the respiratory chain. This suggests that damage of sensitive CNS structures in the WKS is due to energy failure.