Bismuth subsalicylate may cause ringing in the ears, but that side effect is rare. Possible side effects from loperamide include skin rash, constipation, drowsiness, dizziness, tiredness, dry mouth, nausea, vomiting, and swelling, pain, and discomfort in the abdomen.
In the United States, the annual cost of soil erosion for both on-site and off-site effects has been estimated at 44 billion dollars a year (Pimentel et al., 1995). In the European Union, the figure is 38 billion Euros a year (Montanarella, 2007).
In the US in 2007, about 83% of all herbicide usage, determined by weight applied, was in agriculture. : 12 In 2007, world pesticide expenditures totaled about $39.4 billion; herbicides were about 40% of those sales and constituted the biggest portion, followed by insecticides, fungicides, and other types.