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Chagas disease can be transmitted in five different ways: by a vector (through the faeces of an insect), through vertical or congenital transmission (from mother to her child during pregnancy), by way of blood transfusions or organ transplants, by ingesting contaminated food or drinks, or because of laboratory accidents.
Chronic symptomatic Chagas disease. Ten to 30% of persons with chronic Chagas disease develop clinical manifestations of the disease. The most common and serious problems are cardiac, which are caused by an inflammatory cardiopathy that results from the persistent presence of the parasites in the heart.cute phase. In most instances of acute T cruzi infection, a specific diagnosis is not made because of the nonspecific nature of the signs and symptoms and because most cases occur in poor people who have limited access to medical care. Acute Chagas disease carries a mortality rate of less than 5%.