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When Milan was the capital of the west, it surpassed Rome in importance because the imperial court was there. Christianity was made the state religion of the empire with the Edict of Milan. Two fathers of the Catholic church worked in Milan.
The western part's capital was Rome, and the eastern's was Byzantium. Rome remained capital of the western part, although the western part declined while the eastern flourished. Byzantium was later renamed Constantinople in order to honur Constantine.robably one of the biggest effects of Constantine moving east to what became known as Constantinople was that the Pope became important as a secular ruler; which was to have all kinds of unforeseen and unpleasant consequences for the Church.