In summary, the relative refractory period is a time in which the neuron can fire an action potential, but it needs a greater stimulus. During an action potential, voltage-gated sodium channels open to let in positive ions - sodium. These depolarize the cell.
On average, reciting five Mysteries of the Rosary typically takes about 15-20 minutes depending on whether the optional prayers are also recited. Additionally, some people may take longer than 20 minutes if they decide to devote extra time for reflection and meditation on any of the Mysteries.
Many non-Catholic Christians believe that it is wrong to pray to the saints, claiming that our prayers should be directed to God alone. Some Catholics, responding to this criticism, have argued that we do not pray to the saints but with them.