Cushing's syndrome, or hypercortisolism, is a relatively rare hormonal disorder caused by prolonged exposure of the body's tissues to high levels of the hormone cortisol. Symptoms include: upper body obesity, rounded face, increased fat around the neck, thinning arms and legs, fatigue, weakness, high blood pressure, and. mood disorders.
In brief: Uniform standered. Pt is prothrombin time, inr is international normalized ratio, both measure cloting tendency in disease and in health. In pt each time you need contol which varies place to place and some what unpredictble. So inr solves the problem by uniform standred all over the world.
As for addition, the result has the same attribute as the input datetime, and no time zone adjustments are done even if the input is aware. This isnât quite equivalent to datetime1 + (-timedelta), because-timedelta in isolation can overflow in cases where datetime1 - timedelta does not.