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When Milan was the capital of the west, it surpassed Rome in importance because the imperial court was there. Christianity was made the state religion of the empire with the Edict of Milan. Two fathers of the Catholic church worked in Milan.
Justinian's monuments in Istanbul include the domed churches of Hagia Sophia and Hagia Irene, but there is also an earlier, smaller church of Saints Sergius and Bacchus (locally referred to as Little Hagia Sophia), which might have served as a model for both in that it combined the elements of a longitudinal basilica with those of a centralized building.