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Myopathy is a disease of muscle in which the muscle fibers do not function properly. This results in muscular weakness. Myopathy simply means muscle disease (Greek myo- muscle + patheia < -pathy suffering). This meaning implies that the primary defect is within the muscle, as opposed to the nerves (neuropathies or neurogenic disorders) or elsewhere (e.g., the brain).
A clinical diagnosis of myopathy is made when there is muscle pain or weakness accompanied by a creatine kinase (CK) level more than ten times the upper limit of normal. Rhabdomyolysis is a severe form of myopathy with muscle breakdown leading to myoglobinuria, which may result in renal failure and death. clinical diagnosis of myopathy is made when there is muscle pain or weakness accompanied by a creatine kinase (CK) level more than ten times the upper limit of normal. Rhabdomyolysis is a severe form of myopathy with muscle breakdown leading to myoglobinuria, which may result in renal failure and death.