Other helpful Mandarin phrases: While Mandarin has a wealth of generalized insults for the intellectually stunted (Sha gua means retard--literally stupid melon), it really brings the heat with insults that don't sound at all insulting.
frameshift mutation / frame-shift mutation; frameshift. A frameshift mutation is a genetic mutation caused by a deletion or insertion in a DNA sequence that shifts the way the sequence is read. A DNA sequence is a chain of many smaller molecules called nucleotides.
This type of mutation is a change in one DNA base pair that results in the substitution of one amino acid for another in the protein made by a gene.rameshift mutation (illustration). This type of mutation occurs when the addition or loss of DNA bases changes a geneâs reading frame. A reading frame consists of groups of 3 bases that each code for one amino acid. A frameshift mutation shifts the grouping of these bases and changes the code for amino acids.