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Anatomy and Physiology. Internal derangement of the knee is a mechanical disorder of the knee which interferes with normal joint motion and/or mobility. A fragment of soft tissue or bone that suddenly becomes interposed between the articular surfaces is the classic cause of internal derangement.natomy and Physiology. Internal derangement of the knee is a mechanical disorder of the knee which interferes with normal joint motion and/or mobility. A fragment of soft tissue or bone that suddenly becomes interposed between the articular surfaces is the classic cause of internal derangement.
Joints in your body are cushioned by cartilage to prevent bone ends from rubbing together or cause friction. The most common location of chondral injury or damage is the knee joint. The cartilage covers the ends of bones in a joint.