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DMT is a powerful hallucinogen, meant to be carefully administered in a calm environment to someone who has prior experience with other psychedelic drugs. The drug is relatively rare due to the lack of commercial demand and the scarcity of people with the knowledge and motivation to isolate it from plants.
For instance, 5-MeO-DMT rarely produces the visual effects typical of other psychedelics and ibogaine (a 'complex tryptamine') is also an NMDA receptor antagonist and Îº-opioid receptor agonist in addition to being an agonist for the 5-HT2A receptors, resulting in dissociative effects as well (see dissociatives below).