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RSI originated in the anesthesia literature to prevent aspiration in unprepped patients undergoing general anesthesia. From the first anecdotal reports of p-RSI in 1972, prehospital intubation has matured into widespread use. The often conflicting outcome data underscored the need to standardize the approach to p-RSI.
On October 16, William T. G. Morton (1819-1868) made history by being first in the world to publicly and successfully demonstrate the use of ether anesthesia for surgery. This occurred at what came to be called The Ether Dome, at Massachusetts General Hospital on patient Edward Gilbert Abbott.