Bismuth subsalicylate may cause ringing in the ears, but that side effect is rare. Possible side effects from loperamide include skin rash, constipation, drowsiness, dizziness, tiredness, dry mouth, nausea, vomiting, and swelling, pain, and discomfort in the abdomen.
In the United States, the annual cost of soil erosion for both on-site and off-site effects has been estimated at 44 billion dollars a year (Pimentel et al., 1995). In the European Union, the figure is 38 billion Euros a year (Montanarella, 2007).
BY Valerie Paris, OECD February 7, 2014 at 12:15 PM EDT. Photo by Flickr user Images_of_Money. The United States spends almost $1,000 per person per year on pharmaceuticals. Thatâs around 40 percent more than the next highest spender, Canada, and more than twice as much as than countries like France and Germany spend.eneric penetration is high in the U.S. and their use spreads quickly: within six months of a patent expiring on a drug, generics typically account for 80 percent of the market. Generics now account for 28 percent of pharmaceutical spending and 84 percent of drugs dispensed in the U.S., which is high by OECD standards.