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The pericardium (from the Greek ÏÎµÏÎ¯, around and ÎºÎ¬ÏÎ´Î¹Î¿Î½, heart) is a double-walled sac containing the heart and the roots of the great vessels. The pericardial sac has two layers, a serous layer and a fibrous layer. It encloses the pericardial cavity which contains pericardial fluid. The pericardium fixes the heart to the mediastinum, gives protection against infection, and provides the lubrication for the heart.
endocardium - the membrane that lines the cavities of the heart and forms part of the heart valves. pericardium - a serous membrane with two layers that surrounds the heart. epicardium, visceral pericardium - the innermost of the two layers of the pericardium. parietal pericardium - the tough outermost layer of the pericardium that is attached to the diaphragm and the sternum.