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Anatomy and Physiology. Internal derangement of the knee is a mechanical disorder of the knee which interferes with normal joint motion and/or mobility. A fragment of soft tissue or bone that suddenly becomes interposed between the articular surfaces is the classic cause of internal derangement.natomy and Physiology. Internal derangement of the knee is a mechanical disorder of the knee which interferes with normal joint motion and/or mobility. A fragment of soft tissue or bone that suddenly becomes interposed between the articular surfaces is the classic cause of internal derangement.
1 Gout and pseudo-gout can also cause fluid on the knee. 2  Uric acid crystals can accumulate in the knee through gout, leading to the knee jointâs inflammation and swelling, while there also could be the formation of calcium crystals in the knee through pseudo-gout.he treatment method when your knee has fluid on it depends on how the fluid built up around or in the knee joint. These are some of the methods that may be considered: 1  Rest â The pain experienced in the knee will reduce with adequate rest, especially if fluid on the knee was caused by a traumatic injury.