Maraviroc is an entry inhibitor. Specifically, maraviroc is a negative allosteric modulator of the CCR5 receptor, which is found on the surface of certain human cells. The chemokine receptor CCR5 is an essential co-receptor for most HIV strains and necessary for the entry process of the virus into the host cell.
January 14, 1742. Greenwich, England. Edmond Halley, Edmond also spelled Edmund (born Nov. 8, 1656, Haggerston, Shoreditch, near Londonâdied Jan. 14, 1742, Greenwich, near London) English astronomer and mathematician who was the first to calculate the orbit of a comet later named after him.
The most-recent appearance of Halleyâs Comet in 1986 was greatly anticipated. Astronomers first imaged the comet with the 200-inch Hale Telescope at Palomar Observatory in California on October 16, 1982, when it was still beyond the orbit of Saturn at 11.0 AU (1.65 billion km [1 billion miles]) from the Sun.