Recent News: The Deep. Natalie Farrow was recently cast on Freeform's new pilot The Deep. They are waiting to see if it get's picked up, Catch Natalie Farrow's interview, talking all things iZombie and what it was like to play Ginger.
Caffeine can increase blood pressure; long term consumption at sufficiently high doses has been associated with chronic arterial stiffness. Blood pressure increases are mediated by adenosine receptor antagonism. Caffeine can cause vasoconstriction. It is unclear if caffeine causes increased heart rate as a side effect.
Caffeine causes calcium to be excreted in the urine and feces. For every 150 mg of caffeine ingested, about the amount in one cup of coffee, 5 mg of calcium is lost. This effect occurs even hours after the consumption of caffeine. One study of postmenopausal women found that those who consumed more than 300 mg of caffeine lost more bone in the spine than women who consumed less.