Other helpful Mandarin phrases: While Mandarin has a wealth of generalized insults for the intellectually stunted (Sha gua means retard--literally stupid melon), it really brings the heat with insults that don't sound at all insulting.
frameshift mutation / frame-shift mutation; frameshift. A frameshift mutation is a genetic mutation caused by a deletion or insertion in a DNA sequence that shifts the way the sequence is read. A DNA sequence is a chain of many smaller molecules called nucleotides.
The earlier in the sequence the deletion or insertion occurs, the more altered the protein. A frameshift mutation is not the same as a single-nucleotide polymorphism in which a nucleotide is replaced, rather than inserted or deleted.A frameshift mutation will in general cause the reading of the codons after the mutation to code for different amino acids.The frameshift mutation will also alter the first stop codon (UAA, UGA or UAG) encountered in the sequence.The polypeptide being created could be abnormally short or abnormally long, and will most likely not be functional.he frameshift mutation will also alter the first stop codon (UAA, UGA or UAG) encountered in the sequence. The polypeptide being created could be abnormally short or abnormally long, and will most likely not be functional.