Crime: The crime rate fell every year that Clinton was president and was at a 26-year low by the end of his two terms. He got funding for 100,000 new police officers nationwide. He signed the 1993 Brady Bill requiring a waiting period and background check to purchase handguns.
Ns-NSAIDs and coxibs reduce proteinuria without reduction of blood pressure. Their possible role as an adjunct in individualised treatment strategies, particularly for individual patients resistant or intolerant to current therapy, will be discussed.
COX-1 vs COX-2 selectivity of NSAIDs. IC50 (amount needed to inhibit 50% of enzyme activity) If IC50 of COX2/IC50 of COX1 is greater than 1 (as in Aspirin, 166), the NSAID is COX-1 selective (so much more aspirin is needed to inhibit COX2) If IC50 of COX2/IC50 of COX1 is less than 1 (as in Nimesulide, 0.018), the NSAID is COX-2 selective (more Nimesulide is required to inhibit COX1)