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Dexamethasone commonly is used in horses to treat allergic reactions such as respiratory allergies, chronic obstructive pulmonary disease (heaves), hives, itching and inflammatory diseases including arthritis.
Dexamethasone is also used in some diagnostic tests, including the Low-Dose Dexamethasone Suppression test (LDDS). This test involves an initial baseline blood sample, an injection of the Dexamethasone, and two subsequent blood draws 4 and 8 hours later. Dexamethasone will suppress the amount of cortisol in a healthy dog, and the cortisol levels will be less than the level before the injection.