A debt-to-GDP ratio of 60% is quite often noted as a prudential limit for developed countries. This suggests that crossing this limit will threaten fiscal sustainability. For developing and emerging economies, 40% is the suggested debt-to-GDP ratio that should not be breached on a long-term basis.
1 Telomerase is found in high levels in germline cells (egg and sperm) and stem cells. 2  In these cells telomere length is maintained after DNA replication and the cells do not show signs of ageing. 3  Telomerase is also found in high levels in cancer cells.
Why are telomeres important? Telomeres allow cells to distinguish chromosome ends from broken DNA If DNA is broken there are two options after the cell cycle is stopped: Repair or Death Repair can occur in two ways: Homologous Recombination (HR) -- Error-free but need homologue nearby.