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Androgenic and anabolic steroids have been implicated in four distinct forms of liver injury: transient serum enzyme elevations, an acute cholestatic syndrome, chronic vascular injury to the liver (peliosis hepatis) and hepatic tumors including adenomas and hepatocellular carcinoma.ndrogenic and anabolic steroids have been implicated in four distinct forms of liver injury: transient serum enzyme elevations, an acute cholestatic syndrome, chronic vascular injury to the liver (peliosis hepatis) and hepatic tumors including adenomas and hepatocellular carcinoma.
Anabolic steroids have long been used by athletes to improve their performance [ 12 ]. They have potent anabolic effects on the musculoskeletal system, including an increase in lean body mass, a dose-related hypertrophy of muscle fibers, and an increase in muscle strength and mass [ 13 ].nabolic steroids have been used by athletes for half a century. Most of those athletes self administered high doses. Effects and side effects of those supraphysiologic doses are well documented in the literature [ 34 ].