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Causes. Nodules can be caused by a simple overgrowth of normal thyroid tissue, fluid-filled cysts, inflammation (thyroiditis), or a tumor (either benign or cancerous). Most nodules were surgically removed until the 1980s.
Causes of pulmonary nodules include: 1. Infection of the lungs, including infections by tuberculosis, parasites or fungi that may have happened years or even decades ago. 2. Exposure to certain types of lung irritants, such as coal dust or silica. 3.