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Allocation ratio-The ratio of intended numbers of participants in each of the comparison groups. For two group trials, the allocation ratio is usually 1:1, but unequal allocation (such as 1:2) is sometimes used.
Several considerations can influence the decision about the allocation ratio: 1  Available patients â patients limited â equal groups. 2  Cost of treatment â one treatment very expensive â more on cheaper treatment. 3  Resources for treatment â resources limited â more on unlimited treatment.