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Freebase(0.00 / 0 votes)Rate this definition: Cork cambium. Cork cambium is a tissue found in many vascular plants as part of the periderm. The cork cambium is a lateral meristem and is responsible for secondary growth that replaces the epidermis in roots and stems.
Mature cork cells are dead; their cell walls contain suberine, a fatty substance that repels water. The layer of cork provides protection against desiccation, but it also isolates tissues in the inner parts of the stem or trunk so thoroughly that exchange of gas with the outer world is impeded.