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Von Willebrand disease, type 2B: Introduction. Von Willebrand disease, type 2B: A rare inherited blood coagulation disorder characterized by a defect in plasma protein called the von Willebrand factor which leads to bleeding problems. Type 2 vWD is further subdivided into 4 subtypes, each with a different underlying genetic defect.
Von Willebrand Disease. Find out more about von Willebrand disease (VWD), the most common bleeding disorder, affecting up to 1% of the US population. Here you will find information on how factor deficiencies I, II, V, VII, X, XI, XII and XIII are inherited, identified and managed.