Onii can end with 3 different Japanese honourifics, -San, -Chan, or -Sama. -San is the basic ending for the basic big bro. -Sama is a bit of a formal ending for big brother, nothing too special. I really love my Onii-Chan!
Almost 300 million people suffer from acute malaria each year. 40 % of the worldâs population live in areas with malaria risk. Malaria, seen as a consequence of poverty, is also a major cause of poverty and its prevention is an important part of poverty alleviation.
Most deaths from malaria are caused by P. falciparum, which causes severe disease. Before P. falciparum malaria causes a red blood cell to burst, it can make the surface of the cell stick to other cells like it. This causes the blood to clot within small blood vessels, which can severely damage organs.