Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis (MTB).[1] Tuberculosis generally affects the lungs, but can also affect other parts of the body. Most infections do not have symptoms, in which case it is known as latent tuberculosis.
Partial foot amputation (. ) is a common sequel to advanced vascular disease secondary to diabetes and its complications but may also occur due to injury, infection, or birth defect. affects about 2 per 1000 head of population in industrialised countries making it the most common type of amputation surgery.
Overall, amputations of the toe and mid-foot were the most frequent (99 out of 140 patients with amputations receiving canagliflozin in the two trials); however, amputations involving the leg, below and above the knee, were also observed (41 out of 140 patients with amputations receiving canagliflozin in the two trials).