The signal transduction pathway is the mechanism by which the energy of a photon signals a mechanism in the cell that leads to its electrical polarization. 1  This polarization ultimately leads to either the transmittance or inhibition of a neural signal that will be fed to the brain via the optic nerve.
The Inland Empire (I.E.) is a metropolitan area and region of Southern California. It is situated directly east of the Los Angeles metropolitan area.
Inland Empire is the first Lynch feature to be completely shot in digital video; it was shot with a Sony DSR-PD150. Lynch has stated that he will no longer use film to make motion pictures. In an NPR interview, Laura Dern recounted a conversation she had with one of the movie's new producers.