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1 During the first half of the 20th century, no effective treatment was available. 2  Streptomycin, the first antibiotic to fight TB, was introduced in 1946, and isoniazid (Laniazid, Nydrazid), originally an antidepressant medication, became available in 1952. 3  M. tuberculosis is a rod-shaped, slow-growing bacterium.
But some TB infections need to be treated for up to 2 years. Tuberculosis is either latent or active. 1  Latent TB means that you have the TB bacteria in your body, but your body's defenses (immune system) are keeping it from turning into active TB.2  Active TB means that the TB bacteria are growing and causing symptoms.ut some TB infections need to be treated for up to 2 years. Tuberculosis is either latent or active. 1  Latent TB means that you have the TB bacteria in your body, but your body's defenses (immune system) are keeping it from turning into active TB.