1 Junior-Used by his father, even in Indy's adulthood. 2  After discovering that he had a son in 1957, Indiana Jones jokingly referred to Henry Jones III as Junior. 3  Indiana-Taken from the name of his childhood dog, Indiana, often shortened to Indy.
second-site mutation. see suppressor mutation. silent mutation. one in which there is a base change but because of the redundancy of the genetic code the same amino acid is coded, or one in which there is an amino acid substitution in the protein which has no detectable effect on the phenotype.
Mutations in the RAS gene family (HRAS, KRAS, and NRAS) have been observed in a variety of cancers (Table 1). They are activating mutations that result in continual signal transduction, stimulating downstream signaling pathways involved in cell growth, proliferation, invasion, and metastasis.