Centers on Maddie, a party girl and a highly functioning addict who makes the difficult decision to live with other recovering addicts at a rehab facility, while facing the daily pressures of her teenage life.
In biology, a mutation is the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements.
Point mutations are single base changes in a gene's DNA sequence. They can be further categorized: 1  Missense mutations cause a single amino acid change within the protein. 2  Nonsense mutations create a premature stop codon, causing the protein to be shortened. 3  Silent mutations do not cause amino acid changes.