It is the form of energy produced in the mitochondria and is the cell's engine responsible for all cell. function. b. It is the form of energy produced in the endoplasmic reticulum and is the cell's engine responsible for. all cell function.
Pepsinâs main function is to break down proteins that are found in protein rich foods such as meat, eggs etc. It breaks them into smaller pieces called polypeptides. Interesting thing about pepsin is that it breaks proteins only at certain points so that the protein is not digested completely to the amino acid level.epsinogen is a pro-form zymogen of pepsin. It is released in the stomach by its chief cells. This zymogen is activated by hydrochloric acid released from parietal cells in the stomach linings.
Pepsin cleaves Phe1Val, Gln4His, Glu13Ala, Ala14Leu, Leu15Tyr, Tyr16Leu, Gly23Phe, Phe24 in the insulin B chain. Pepsin exhibits maximal activity at pH 2.0 and is inactive at pH 6.5 and above, however pepsin is not fully denatured or irreversibly inactivated until pH 8.0. Therefore, pepsin in solution of up to pH 8.0 can be reactivated upon re-acidification. The stability of pepsin at high pH has significant implications on disease attributed to laryngopharyngeal reflux. Pepsin remains in the larynx following a gastric reflux event. At the mean pH of the laryngopharynx (pH = 6.8) pepsin would be inactive but could be reactivated upon subsequent acid reflux events resulting in damage to local tissues. In laryngopharyngeal reflux. Pepsin is one of the primary causes of mucosal damage during laryngopharyngeal reflux. Pepsin remains in the larynx (pH 6.8) following a gastric reflux event. While enzymatically inactive in this environment, pepsin would remain stable and could be reactivated upon subsequent acid reflux events.