Tissue homeostasis can also depend on the maintenance of body functions like digestion, respiration, urination, and lymphatic control. The health of the skin is typically important, along with normal skeletal support, muscle movement, and responses between the nervous system and muscles.
Practice Essentials. Angioedema is the swelling of deep dermis, subcutaneous, or submucosal tissue due to vascular leakage.Acute episodes often involve the lip, eyes, and face (see the image below); however, angioedema may affect other parts of body, including respiratory and gastrointestinal (GI) mucosa.
Hives and angioedema are reactions of the skin to histamine and other chemicals such as bradykinin, leukotriene C4, and prostaglandin D2. These chemicals act on blood vessels and other tissues to produce the clinical signs of hives and angioedema. This process is often, although not always, due to an allergic reaction.