During Larry Nassar's sexual abuse trial and sentencing, victims' harrowing stories have brought to light Ehlers-Danlos Syndrome (EDS), a condition that is common among gymnasts, but poorly understood.
A mechanism by which different forms of mature mRNAs are generated from the same gene. Alternative splicing is a regulatory mechanism by which variations in the incorporation of the exons, or coding regions, into mRNA leads to the production of more than one related protein, or isoform. RNA interference.
Think of it like a search-and-rescue mission for DNA. Crispr uses guide RNA as a homing device; it's designed in a lab to match up with a section of DNA designated for editing. In therapeutic uses, this could be a genetic abnormality that causes disease. That guide molecule is joined with an enzyme known as Cas9 (CRISPR's fuller name is actually CRISPR-Cas9). The enzyme acts like scissors, making a cut in the DNA where the RNA guided. By adding DNA with the correct sequence, scientists hope to be able to correct the underlying genetic defects that cause disease.