The signal transduction pathway is the mechanism by which the energy of a photon signals a mechanism in the cell that leads to its electrical polarization. 1  This polarization ultimately leads to either the transmittance or inhibition of a neural signal that will be fed to the brain via the optic nerve.
The Inland Empire (I.E.) is a metropolitan area and region of Southern California. It is situated directly east of the Los Angeles metropolitan area.
Fresno is the largest inland city in California. 6 Sacramento 489,488 Sacramento Sacramento has been the state capital of California since 1879. Once the state's second largest city, Sacramento was a major distribution center during the California Gold Rush and was the western terminus of the Pony Express.