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Goiter: A noncancerous enlargement of the thyroid gland. With a goiter, the levels of thyroid hormones may be normal (euthyroid), elevated (hyperthyroidism), or decreased (hypothyroidism). Last Editorial Review: 5/13/2016.
A Major Player in Regulating Your Metabolism. 1  Goiters: A goiter is a bulge in the neck. A toxic goiter is associated with hyperthyroidism, and a non-toxic goiter, also known as a simple or endemic goiter, is caused by iodine deficiency. 2  Hyperthyroidism: Hyperthyroidism is caused by too much thyroid hormone.