Onii can end with 3 different Japanese honourifics, -San, -Chan, or -Sama. -San is the basic ending for the basic big bro. -Sama is a bit of a formal ending for big brother, nothing too special. I really love my Onii-Chan!
Almost 300 million people suffer from acute malaria each year. 40 % of the worldâs population live in areas with malaria risk. Malaria, seen as a consequence of poverty, is also a major cause of poverty and its prevention is an important part of poverty alleviation.
Human malaria is caused by infection with intracellular parasites of the genus Plasmodium that are transmitted by Anopheles mosquitoes. Of the four species of Plasmodium that infect humans, Plasmodium falciparum is the most lethal. Resistance to anti-malarial drugs and insecticides, the decay of public health infrastructure, population movements, political unrest, and environmental changes are contributing to the spread of malaria.