The central volume of distribution (Vc) is a hypothetical volume into which a drug initially distributes upon administration. This compartment can be thought of as the blood in vessels and tissues which are highly perfused by blood. The peripheral volume is the sum of all tissue spaces outside the central compartment.
Knot Note: Start thinking about bridesmaid dresses about six months before your wedding to allow enough time to decide on, order, and fit the dresses. It takes two to three months for the dresses to arrive, and four to six weeks for alterations.
Per general etiquette, the mother of the bride buys her wedding day outfit first, then notifies the mother of the groom about the color, length and overall formality of her choice. But if the groom's mom doesn't get word by the four-month mark, she should touch base with the bride-to-be about what to do.