A debt-to-GDP ratio of 60% is quite often noted as a prudential limit for developed countries. This suggests that crossing this limit will threaten fiscal sustainability. For developing and emerging economies, 40% is the suggested debt-to-GDP ratio that should not be breached on a long-term basis.
1 Telomerase is found in high levels in germline cells (egg and sperm) and stem cells. 2  In these cells telomere length is maintained after DNA replication and the cells do not show signs of ageing. 3  Telomerase is also found in high levels in cancer cells.
Telomerase is a large multisubunit RNP. Telomerase is a reverse transcriptase that adds telomere repeats to chromosome ends. The minimal catalytic core is composed of TERT, the telomerase reverse transcriptase, and TERC, the telomerase RNA, which acts as the template for telomere addition.elomeres protect chromosome ends. Telomeres are TTAGGG double-stranded DNA repeats culminating in a single-stranded overhang. The shelterin protein complex protects telomeres, facilitates replication and controls access of telomerase.