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Causes. Nodules can be caused by a simple overgrowth of normal thyroid tissue, fluid-filled cysts, inflammation (thyroiditis), or a tumor (either benign or cancerous). Most nodules were surgically removed until the 1980s.
What causes lung nodules? Quick Answer. According to the Seattle Cancer Care Alliance, lung, or pulmonary, nodules have numerous causes, including fungal or bacterial infection, sarcoidosis, lymphoma, lung cancer and cancers metastasized from other organs.