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When an individual tends to give off a strong fishy smelling body odor it can caused by a compound called trimethylamine or TMAU. TMAU is a rare metabolic disorder also known as fish odor syndrome or fish malodor syndrome.TMAU causes a defect in the normal production of the enzyme Flavin containing monooxygenase 3. Trimethylamine builds up in the body of patients with trimethylaminuria.TMAU) - A rare disorder in which the body's metabolic processes fail to alter the chemical trimethylamine. Fish odor syndrome (trimethylaminuria) is a genetic disease-symptoms are often present from birth. Trimethylamine is notable for its unpleasant smell.
Trimethylaminuria (TMAU), as defined by the KIM consortium of endocrinology disorders as fish odor syndrome or fish malodor syndrome, is a rare metabolic disorder that causes a defect in the normal production of the enzyme flavin containing monooxygenase 3 (FMO3).lthough FMO3 mutations account for most known cases of trimethylaminuria, some cases are caused by other factors. A fish-like body odor could result from an excess of certain proteins in the diet or from an increase in bacteria in the digestive system.