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Common signs and symptoms of post-acute withdrawal can include:4. 1  Anxiety. 2  Depression. 3  Changes in mood.  Low 1  energy. Insomnia.  Poor 1  concentration. Low libido.  Unexplainable physical pain.
Symptoms of opiate withdrawal usually begin within 12 hours of the last heroin use or within 30 hours of the last methodone use. Initial withdrawal symptoms peak after about three days and tend to last for five days.Flu-like symptoms generally subside after ten days. Many people try to quit heroin and opiate use alone.This is often a very dangerous and potentially fatal decision. The major symptoms* of acute withdrawal are: 1  Depression. 2  Insomnia. 3  Nausea. 4  Vomiting. 5  Diarrhea. 6  Abdominal cramps.any people try to quit heroin and opiate use alone. This is often a very dangerous and potentially fatal decision. The major symptoms* of acute withdrawal are: 1  Depression. 2  Insomnia. 3  Nausea. 4  Vomiting. 5  Diarrhea.