Onii can end with 3 different Japanese honourifics, -San, -Chan, or -Sama. -San is the basic ending for the basic big bro. -Sama is a bit of a formal ending for big brother, nothing too special. I really love my Onii-Chan!
Almost 300 million people suffer from acute malaria each year. 40 % of the worldâs population live in areas with malaria risk. Malaria, seen as a consequence of poverty, is also a major cause of poverty and its prevention is an important part of poverty alleviation.
1 P. malariae, found worldwide, is the only human malaria parasite species that has a quartan cycle (three-day cycle). ( 2 The three other species have a tertian, two-day cycle.) If untreated, P. malariae causes a long-lasting, chronic infection that in some cases can last a lifetime. P. falciparum can cause severe malaria because it multiples rapidly in the blood, and can thus cause severe blood loss (anemia). 2  In addition, the infected parasites can clog small blood vessels. 3  When this occurs in the brain, cerebral malaria results, a complication that can be fatal.