1 Junior-Used by his father, even in Indy's adulthood. 2  After discovering that he had a son in 1957, Indiana Jones jokingly referred to Henry Jones III as Junior. 3  Indiana-Taken from the name of his childhood dog, Indiana, often shortened to Indy.
second-site mutation. see suppressor mutation. silent mutation. one in which there is a base change but because of the redundancy of the genetic code the same amino acid is coded, or one in which there is an amino acid substitution in the protein which has no detectable effect on the phenotype.
Wilm's tumour tumor suppressor gene1 (WT1) causes an embryonic malignancy of the kidney, affecting around 1 in 10,000 infants. It occurs in both sporadic and hereditary forms. Inactivation of WT1 causes Wilm's tumour, and Denys-Drash syndrome (DDS), leading to nephropathy and genital abnormalities. The WT1 protein has been found to bind a host of cellular factors, e.g. p53, a known tumor suppressor.