Another way to describe the two solutions in the example of above is to use the terms hypertonic and hypotonic. A hypertonic solution has more solutes and less water than a hypotonic solution. So, in the example above, the solution inside the cell is hypertonic to the solution outside the cell.
Body Blood Volume calculator Formula: Man: BV = 0.3669 Ã h3+ 0.03219 Ã w + 0.6041. Woman: BV = 0.3561 Ã h3 + 0.03308 Ã w + 0.1833. Where: h: Body height, in meters. w: Body weight, in kilograms. BV: Body Total Blood Volume, in liters.
Apparent volume of distribution, V. We can use Equation 5.7.1 to calculate the plasma concentration at any time when we know kel and Cp0. However, usually we don't know Cp0 ahead of time, but we do know the dose. A dose in mass units, maybe in mg. To calculate Cp0 we need to know the volume that the drug is distributed into. That is, the apparent volume of the mixing container, the body. This apparent volume of distribution is not a physiological volume. It won't be lower than blood or plasma volume but for some drugs it can be much larger than body volume.