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Androgenic and anabolic steroids have been implicated in four distinct forms of liver injury: transient serum enzyme elevations, an acute cholestatic syndrome, chronic vascular injury to the liver (peliosis hepatis) and hepatic tumors including adenomas and hepatocellular carcinoma.ndrogenic and anabolic steroids have been implicated in four distinct forms of liver injury: transient serum enzyme elevations, an acute cholestatic syndrome, chronic vascular injury to the liver (peliosis hepatis) and hepatic tumors including adenomas and hepatocellular carcinoma.
Liver Damage. Chronic use of some drugs, such as heroin, inhalants, and steroids (appearance- and performance-enhancing drugs), may lead to significant damage to the liver. This damage can be worse when these drugs are combined with alcohol or other drugs. Drugs that can cause liver damage: 1  DXM. 2  heroin. 3  inhalants. steroids (appearance- and performance-enhancing drugs)