A debt-to-GDP ratio of 60% is quite often noted as a prudential limit for developed countries. This suggests that crossing this limit will threaten fiscal sustainability. For developing and emerging economies, 40% is the suggested debt-to-GDP ratio that should not be breached on a long-term basis.
1 Telomerase is found in high levels in germline cells (egg and sperm) and stem cells. 2  In these cells telomere length is maintained after DNA replication and the cells do not show signs of ageing. 3  Telomerase is also found in high levels in cancer cells.
Telomerase RNA component, also known as TERC, is an ncRNA found in eukaryotes, that is a component of telomerase - The enzyme used to extend telomeres. TERC serves as a template for telomere replication by telomerase. Telomerase RNAs differ greatly in sequence and structure between vertebrates, ciliates and yeasts, but they share a 5' pseudoknot structure close to the template sequence. The vertebrate telomerase RNAs have a 3' H/ACA snoRNA-like domain.