Medical conditions known to cause swelling that affects both legs equally include heart disease, kidney disease, liver disease, and chronic sleep apnea, and complications of diabetes. Premenstrual syndrome (PMS) is also a well-known cause of swelling in the ankles and feet.
Definition of serendipity for English Language Learners. : luck that takes the form of finding valuable or pleasant things that are not looked for.
Principlism is a moral approach based on judgments that are generally accepted by most intellectual, cultural and religious traditions. For example, the Belmont Report defines 3 key principles by which to judge the ethicality of biomedical and behavioral research.