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median lethal dose (LD 50) the quantity of an agent that will kill 50 per cent of the test subjects; in radiology, the amount of radiation that will kill, within a specified period, 50 per cent of individuals in a large group or population.ee also median effective dose. erythema dose that amount of radiation that, when applied to the skin, causes erythema (temporary reddening). fatal dose lethal dose.
Lethal Dose Fifty (LD50) is one way the toxicity of chemicals are measured. LD50 is the amount of a pesticide that has killed half of the animals in a laboratory test. The LD50 is found for both dermal and oral routes of exposure.he acute toxicity of a pesticide is used as the basis for the warning statements on the label. Acute toxicity may be measured as acute oral toxicity, acute dermal toxicity, and acute inhalation toxicity. Chronic toxicity is the delayed poisonous effect from exposure to a substance.