Wrist sprains can vary in severity. A mild or grade 1 wrist sprain may involve the ligament being stretched. Moderate or grade 2 injuries are partial tears of a ligament and severe grade 3 injuries are full ruptures of one or more ligaments. Grade 3 injuries may also involve an avulsion fracture where a fragment of bone is pulled off with the ligament.
Basal forebrain cholinergic neurons (BFCNs) are a group of brain cells that are important for attention, learning and memory functions. BFCNs receive input from a protein produced in the hippocampus, called nerve growth factor (NGF).NGF plays a vital role in the well-being of BFCNs.e are happy to announce that the long awaited Down Syndrome Clinic at Stanford will open its doors on July 11th. The clinic is located in the Lucile Packard Childrenâs hospital. To make an appointment, please call the clinical coordinator at (650) 723-6858, extension 1.
Of interest in the context of AD, we have demonstrated that the BFCNs display a regionally and biochemically selective and substantial loss of CB in the course of normal aging in both the human and in non-human primates (Wu et al., 1997, Wu et al., 2003, Geula et al., 2003a and Geula et al., 2003b).n the studies reported here, a multi-use AAV vector system was employed for delivering the CB gene to the rat BFCNs. In one system, a cDNA encoding CB was inserted into pACP, a generic AAV vector in which expression is under the control of CMV immediate early gene promoter.