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median lethal dose (LD 50) the quantity of an agent that will kill 50 per cent of the test subjects; in radiology, the amount of radiation that will kill, within a specified period, 50 per cent of individuals in a large group or population.ee also median effective dose. erythema dose that amount of radiation that, when applied to the skin, causes erythema (temporary reddening). fatal dose lethal dose.
Details. Created on Friday, 04 October 2013 21:17. Nicotine lethal dose in humans: a common argument by regulatory authorities, based on poor science. By Dr Farsalinos. I am sure everyone has heard the âmagic numberâ: 60mg is the nicotine lethal dose in adults.Ï his is a very low level, which would categorize nicotine as one of the most toxic substances available. always wondered how the lethal dose level was defined, because everyone mentioned that the lethal dose was just theoretical and was never really tested. In animals the lethal dose may be from 3mg/kg in mice to 50mg/kg in rats, while a 60mg dose means a 0.8mg/kg in humans.