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Enteroendocrine cells of the intestine are the most numerous endocrine cells of the body. They constitute an enteric endocrine system as a subset of the endocrine system just as the enteric nervous system is a subset of the nervous system.
The endocrine part of the pancreas, the Islets of Langerhans, produces and secretes insulin, the hormone that regulates blood sugar levels. Unniappan's findings indicate that the protein stimulates insulin secretion from the pancreas, a glandular organ, which contains clusters of cells called the islets of Langerhans.