A debt-to-GDP ratio of 60% is quite often noted as a prudential limit for developed countries. This suggests that crossing this limit will threaten fiscal sustainability. For developing and emerging economies, 40% is the suggested debt-to-GDP ratio that should not be breached on a long-term basis.
1 Telomerase is found in high levels in germline cells (egg and sperm) and stem cells. 2  In these cells telomere length is maintained after DNA replication and the cells do not show signs of ageing. 3  Telomerase is also found in high levels in cancer cells.
Telomerase replaces short bits of DNA known as telomeres, which are otherwise shortened when a cell divides via mitosis. In normal circumstances, absent telomerase, if a cell divides recursively, at some point the progeny reach their Hayflick limit, which is believed to be between 50â70 cell divisions.elomerase is a reverse transcriptase enzyme that carries its own RNA molecule (with the pattern of  C C C A A U C C C  in vertebrates), which is used as a template when it elongates telomeres.