The central volume of distribution (Vc) is a hypothetical volume into which a drug initially distributes upon administration. This compartment can be thought of as the blood in vessels and tissues which are highly perfused by blood. The peripheral volume is the sum of all tissue spaces outside the central compartment.
Knot Note: Start thinking about bridesmaid dresses about six months before your wedding to allow enough time to decide on, order, and fit the dresses. It takes two to three months for the dresses to arrive, and four to six weeks for alterations.
So before you say a big yes to the bridesmaid dress, take note of the four things you will be asked to pay for as one of the bride's go-to gal pals for her wedding day. 1. Wedding Pre-Parties. Everyone knows that weddings are super expensive, but nobody really talks about how expensive all of the wedding pre-parties can be.