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Cold sores/chapped lips accutane? i'm on accutane and i always get this cold sore or chapped lip scab on the right side of my lip. it's really annoying and it looks horrible.
Read More. Side effects often occur at the beginning of treatment then wear off as your body gets used to the medicine. However, there are other oral anti-biotics which may suit you better such as oxytetracycline or erythromycin. Accutane is a retinoid, and not related to anti-biotics so the side effects are different. However, the list of potential rare side effects of accutane is long and includes headaches, nausea, muscle pain and depression.