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Chronic pancreatitis is progressive inflammatory process in the pancreas that causes fibrosis (scarring of tissue), calcifications or stones, and dilated pancreatic duct. Adapted from Gorelick F, Pandol, SJ, Topazian M. Pancreatic physiology, pathophysiology, acute and chronic pancreatitis.
In the case of recurring pancreatitis, however, long-term damage to the pancreas is common, sometimes leading to malnutrition and diabetes. Necrotizing pancreatitis (in which pancreatic tissue dies) can lead to cyst-like pockets and abscesses. Because of the location of the pancreas, inflammation spreads easily.