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How long does a BOTOXÂ® injection last? You can expect the effect of your BOTOXÂ® treatment to last anywhere from four to six months. As acetylcholine production returns to normal, your muscles will once again begin to contract and the wrinkles will reappear. That's the bad news. The good news is that your wrinkles may be less prominent after BOTOXÂ® treatment because your muscles may be somewhat trained to be in the more relaxed state. As the wrinkles reappear, you will have to have repeat BOTOXÂ® treatments to get them to disappear again.
Not for Me - Toledo, OH. I tried botox as a last result for chronic migraines. The day after the botox treatment I had a migraine for 2 days all day long, along with a stiff neck. The stiff neck continued for three days with no relief except for taking a muscle relaxant at night but then I would wake up still with a... READ MORE.