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Fig. 1. Differing mechanisms by which conjugated bile acids inhibit bacterial overgrowth of the human small intestine. In the proximal small intestine (duodenum and jejunum), conjugated bile acids (and accompanying fatty acids) inhibit bacterial growth directly because of their pharmacological properties.
Phospholipid-derived fatty acids (PLFA) are widely used in microbial ecology as chemotaxonomic markers of bacteria and other organisms.Phospholipids are the primary lipids composing cellular membranes. Phospholipids can be saponified, which releases the fatty acids contained in their diglyceride tail.ach phospholipid consists of a polar hydrophilic head (red) and two hydrophobic fatty acid tails. The fatty acid structure affects the bilayer structure. Fatty acids with an unsaturated tail (blue) disrupt the packing of those with only saturated tails (black).