A debt-to-GDP ratio of 60% is quite often noted as a prudential limit for developed countries. This suggests that crossing this limit will threaten fiscal sustainability. For developing and emerging economies, 40% is the suggested debt-to-GDP ratio that should not be breached on a long-term basis.
1 Telomerase is found in high levels in germline cells (egg and sperm) and stem cells. 2  In these cells telomere length is maintained after DNA replication and the cells do not show signs of ageing. 3  Telomerase is also found in high levels in cancer cells.
Telomeres are buffer regions of non-coding DNA at the ends of chromosomes that prevent the loss of protein-coding DNA when cells divide. Telomeres get slightly shorter each time a chromosome replicates during cell division, but stress can also cause them to shorten. Shorter telomeres are associated with a raft of diseases in adults from diabetes to dementia.