Medical Definition of configuration. 1  1a: relative arrangement of parts or elementsb: the stable structural makeup of a chemical compound especially with reference to the space relations of the constituent atoms. 2  2: gestalt personality configuration.
Infections with multi-drug resistant E. coli, which is also known as ESBL (extended spectrum beta-lactamase), have been assumed to be a hospital phenomenon.
In many respects, this activity is so dramatic, and the genes so versatile and dispersed, that it truly rivals science fiction. The recognition that bacteria could become multidrug-resistant came as a surprise in the late 1950s and early 1960s.Over the span of a few decades, resistance to single antibiotics has been replaced with multidrug resistance.hen confronted with an antibiotic, they can destroy it with enzymes, rendering it harmless. Some can transport the antibiotic out of a cell via what are called efflux pumps, thereby protecting the inner cell. Alternatively, they can substitute a drug-resistant target for one that is susceptible to the antibiotic.