Examples. 1  Contract research businesses such as Covance conduct many clinical trials and focus on improving efficiency at every step of the process. Eli Lilly Signs R&D Pact With Covance.
Excessive running or walking. Over-use of the thigh and hip muscles leading to the muscle weakness and excessive pressure in kneecap leading to the pain in knee. Wearing wrong shoes causes excessive stress on ligament, cartilage and knee cap resulting in early wear and tear.
LAWRENCE: She has arthritis in the joint right at top, and when she wears a shoe or anything, it hurts, because arthritis, there is a bursitis that goes along with... L. KING: So if she weren't wearing shoes, she wouldn't have the pain. LAWRENCE: She'll have less pain if she doesn't have the shoe rubbing over it.