People who take opioids for pain relief for extended periods of time may need higher doses to ease their pain. They may develop tolerance to the drug and experience withdrawal symptoms if the medication is abruptly stopped. They become physically dependent on the drug.
Antibiotics most likely to cause C. diff infections are clindamycin, amoxicillin, ampicillin, and cephalosporins, and to a lesser extent, penicillin, erythromycin, and quinolones.
Clostridium difficile, also known as C. difficile or C. diff, is a bacterium that can infect the bowel and cause diarrhoea. The infection most commonly affects people who have recently been treated with antibiotics, but can spread easily to others.