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Causes of Menorrhagia. There are many possible causes of heavy menstrual bleeding. They include: 1  Hormonal imbalance, particularly in estrogen and progesterone; this is most common in adolescents who recently began their periods and women who are getting close to menopause.
A hormonal imbalance during adolescence or menopause is the most common cause of heavy menstrual bleeding. During adolescence, after girls have their first periods and for several years before the onset of menopause, our hormone levels are fluctuating, which often leads to excessive uterine bleeding during our periods.