Pulmonary arterial hypertension (PAH) is a progressive condition that affects the heart and lungs. It is characterized by abnormally high blood pressure (hypertension) in the pulmonary artery, the blood vessel that carries blood from the heart to the lungs.
The Protein Complexes of the Electron Transport Chain. Many years of effort have been devoted to the study of the remarkable processes in the mitochondria. The electron transport chain is the final stage of aerobic respiration leading to the forming of ATP in the inner membrane of the mitochondrion. The emergent picture is that of coupled reactions through five protein structures associated with that inner membrane.
In eukaryotes, an important electron transport chain is found in the inner mitochondrial membrane where it serves as the site of oxidative phosphorylation through the use of ATP synthase. It is also found in the thylakoid membrane of the chloroplast in photosynthetic eukaryotes.n mitochondria, it is the conversion of oxygen to water, NADH to NAD + and succinate to fumarate that are required to generate the proton gradient. Electron transport chains are major sites of premature electron leakage to oxygen, generating superoxide and potentially resulting in increased oxidative stress.