Stickler syndrome or hereditary progressive arthro-ophthalmopathy[1] (ORPHA828) is a connective tissue disorder affecting about 1/7,500 to 1/9,000 newborns[2]. It is characterized by ocular, skeletal, orofacial, and auditory abnormalities.
Mayflower Park â Downtown Seattle Hotel. Mayflower Park â downtown Seattle Hotel â Welcome to the historic Mayflower Park Hotel. Ideally located in thriving downtown Seattle, the Mayflower Park is in the heart of the city. Built in 1927, the classic Mayflower Park Hotel has been lovingly restored with crystal chandeliers, gleaming brass and period antiques that offer an inviting European elegance to this historic Seattle hotel.
In the heart of the charming historic district in Charleston sits The Elliott House Inn, one of the most beloved historic Charleston hotels. Nestled beneath centuries-old oaks, this Charleston bed-and-breakfast is a welcoming respite from everyday life that is beloved by visitors and locals alike.