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Answer: Ischemic white matter disease refers to small blood vessels in the brain that are clogging up a bit. This is usually not a serious condition unless the amount of small vessel disease gets to a moderate or severe degree.It is often caused by high blood pressure, diabetes, high cholesterol, or smoking.nswer: Ischemic white matter disease refers to small blood vessels in the brain that are clogging up a bit. This is usually not a serious condition unless the amount of small vessel disease gets to a moderate or severe degree.
Ischemia is the condition or state in which a tissue such as brain is subjected to hypoxia or low oxygen because of an obstruction of the arterial blood supply or inadequate blood flow. Brain ischemia can be broadly divided into two main classifications, global ischemia and focal ischemia. Global ischemia is the condition or state in which blood flow to the entire brain is transiently blocked, which results in delayed, selective neuronal death.