Carotid arteries: When you have clogged arteries in your brain, it is a condition called carotid artery disease. Plaque will block or narrow the carotid arteries, and signs of a stroke may be present. Symptoms include breathing problems, sudden weakness, confusion, severe headaches, loss of consciousness, blurry vision, trouble with speech, paralysis, trouble walking, dizziness, unexplained falls, and loss of coordination or balance.
In addition, taking metformin in the long run can lead to kidney failure, digestive disease, diarrhea, etc.so, despite of no kidney problems, patients with diabetes should not rely on metformin in the long term. As a consequent, we can know that metformin has side effects on kidney, doing harm to kidney function.
Gastrointestinal side effects are common with metformin therapy and significant diarrhea or vomiting, particularly when there is underlying chronic renal disease, can lead to severe dehydration and acute renal failure.xList reports the most common side effects associated with metformin, occurring in more than 5 percent of patients using the drug, are diarrhea, nausea, vomiting, flatulence, diffuse lack of strength, headache, indigestion and abdominal discomfort. Metformin-induced renal side effects are rare but can be lethal.