Onset of anisocoria: Old patient photographs often help to date anisocoria that is unaccompanied by other symptoms. Physical. Key aspects of the physical examination (eg, pupil size in light, pupil size in the dark, pupil reactivity to light and dark) help to localize the problem. Additional historical features such as pain, diplopia, ptosis, numbness, ataxia, dysarthria, or weakness help generate a differential diagnosis.
Mount Agung last erupted in 1963 (see information box in this article). This was one of the largest 20th century eruptions anywhere in the world. Historical eruptions of the volcano are poorly recorded, but there was certainly one in the 1820s.
Version 1.0. The largest eruption on Earth this century occurred at Novarupta Volcano, Alaska, in June 1912, creating Katmai Caldera and the Valley of Ten Thousand Smokes. Volcanic ash (more than from all other historical eruptions in Alaska combined) devastated areas hundreds of miles away.ersion 1.0. The largest eruption on Earth this century occurred at Novarupta Volcano, Alaska, in June 1912, creating Katmai Caldera and the Valley of Ten Thousand Smokes. Volcanic ash (more than from all other historical eruptions in Alaska combined) devastated areas hundreds of miles away.