1 Cover tightly. 2  Preheat oven to 425 degrees F for 15 minutes. 3  Place the roast in the oven and immediately reduce the temperature down to 200 degrees F. 4  Roast for about 4 hours or until the meat is falling-apart tender (cooking time will vary depending on the size of the roast).
intrinsic. adj. 1. of or relating to the essential nature of a thing; inherent. 2. (Anatomy) anatomy situated within or peculiar to a part: intrinsic muscles. [C15: from Late Latin intrinsecus from Latin, inwardly, from intrÄ within + secus alongside; related to sequÄ« to follow].
Intrinsic muscles. Definition. noun. A group of muscles located within or situated deeper in a structure, in contrast to extrinsic muscles located rather superficially. Supplement. Based on the above definition, the intrinsic muscles refer to the muscles closest to the axial and appendicular skeleton.For example, the intrinsic muscles of the hand are those lying deeper in the hand, such as the interossei and lumbrical muscles.ased on the above definition, the intrinsic muscles refer to the muscles closest to the axial and appendicular skeleton. For example, the intrinsic muscles of the hand are those lying deeper in the hand, such as the interossei and lumbrical muscles.