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Answer: Ischemic white matter disease refers to small blood vessels in the brain that are clogging up a bit. This is usually not a serious condition unless the amount of small vessel disease gets to a moderate or severe degree.It is often caused by high blood pressure, diabetes, high cholesterol, or smoking.nswer: Ischemic white matter disease refers to small blood vessels in the brain that are clogging up a bit. This is usually not a serious condition unless the amount of small vessel disease gets to a moderate or severe degree.
Less blood flow means that the brain tissue can be irreversibly injured, which is referred to as ischemic injury.. Some MRI reports may state that perivascular chronic ischemic white matter disease of aging is seen.We do know that we see increasing amount of these changes with age and see greater amounts of change in patients who have high blood pressure and diabetes.hite matter change is a very common finding on an MRI scan. Frequently, these changes are seen in patients who have/have had hypertension, stroke, migraine headaches, or other medical conditions.