Sebastiano /se-bas-tia-no/ [4 sylls.] as a boys' name. Sebastiano's root is Greek, and the meaning of the name Sebastiano is revered. Sebastiano is an alternate spelling of Sebastian (Greek).
All of the aforementioned drugs can be used in combination, to control symptoms, prevent future attacks, and maintain healthy uric acid levels. Krystexxa (pegloticase) is a biologic drug. It works by breaking down uric acid. It is used in gout patients who either failed or cannot tolerate conventional gout medications.
Allopurinol helps to lower uric acid levels by inhibiting the enzyme (xanthine oxidase) responsible for converting purines into uric acid, which reduces the production of uric acid. However, allopurinol is not a painkiller and will have no effect during an attack of gout.