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Answer: Ischemic white matter disease refers to small blood vessels in the brain that are clogging up a bit. This is usually not a serious condition unless the amount of small vessel disease gets to a moderate or severe degree.It is often caused by high blood pressure, diabetes, high cholesterol, or smoking.nswer: Ischemic white matter disease refers to small blood vessels in the brain that are clogging up a bit. This is usually not a serious condition unless the amount of small vessel disease gets to a moderate or severe degree.
White matter tissue of the freshly cut brain appears pinkish white to the naked eye because myelin is composed largely of lipid tissue veined with capillaries. Its white color in prepared specimens is due to its usual preservation in formaldehyde.he white matter is white because of the fatty substance (myelin) that surrounds the nerve fibers (axons). This myelin is found in almost all long nerve fibers, and acts as an electrical insulation.