The drugs they looked at were heroin, cannabis, nicotine, alcohol, methadone, amphetamine and MDMA. As described in Scientific Reports, they found that, at the level of individual use, four substances were classified as high risk: alcohol, nicotine, cocaine and heroin.
Prepping the brisket. Start with a brisket in the 10- to 12-pound range, which is just the right size to fit on the grill. Trim off the excess top fat or âfat cap,â but leave a Â¼-thick layer of fat to keep the meat moist during the long cooking process. Sprinkle on a few tablespoons of rub, spreading it evenly on both sides of the brisket.
Brisket is rubbed with spices and liquid smoke and then cooked in a slow cooker with barbeque sauce until tender and juicy. This calls for just enough barbecue sauce for that smoky flavor while still allowing the flavor of the meat to come through. Hint: It's even better if you marinate it in the dry rub overnight..