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Practical aspects of Ab assays Each Ab assay has its own characteristic advantages and disadvantages based on technical difficulty, intra- and interassay variability (i.e., precision), sensitivity for measuring Abs, specificity for the target protein or ligand, susceptibility to false-positive or false-negative results, and cost.
For the detection of VZV specific IgG, IgM and IgA, ELISA is the method of choice. With the SERION ELISA classic Varicella-. Zoster Virus ELISAs, evaluation of antibody activity is measured in international Units and, therefore, comparison of results from different tests is possible.