People who take opioids for pain relief for extended periods of time may need higher doses to ease their pain. They may develop tolerance to the drug and experience withdrawal symptoms if the medication is abruptly stopped. They become physically dependent on the drug.
Antibiotics most likely to cause C. diff infections are clindamycin, amoxicillin, ampicillin, and cephalosporins, and to a lesser extent, penicillin, erythromycin, and quinolones.
Standard C. diff treatment protocols are usually the antibiotics metronidazole or vancomycin. Some strains of the C. diff bacteria are not responding to antibiotic therapy and are a growing cause of concern around the world.