Carotid arteries: When you have clogged arteries in your brain, it is a condition called carotid artery disease. Plaque will block or narrow the carotid arteries, and signs of a stroke may be present. Symptoms include breathing problems, sudden weakness, confusion, severe headaches, loss of consciousness, blurry vision, trouble with speech, paralysis, trouble walking, dizziness, unexplained falls, and loss of coordination or balance.
In addition, taking metformin in the long run can lead to kidney failure, digestive disease, diarrhea, etc.so, despite of no kidney problems, patients with diabetes should not rely on metformin in the long term. As a consequent, we can know that metformin has side effects on kidney, doing harm to kidney function.
Treatment with metformin can cause a serious condition called lactic acidosis (the accumulation of too much acid in the blood), which requires urgent hospital treatment. Its symptoms include muscle cramps, abdominal pain, breathlessness and a feeling of being very weak and unwell.