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Macules may be of. any size or color. A macule greater than 2 cm. in diameter is called a patch. Ex: cafÃ©-au-lait: Mongolian spot; freckle. 2. Papule: Papule is a solid, elevated lesion with no visible fluid which may be up to Â½. cm. in diameter. The elevation may be accounted for by metabolic deposits, infiltrates, or hyperplasia of cellular elements, etc. A papulosquamous lesion is a papule with desquamation (scaling). 3. Nodules: Nodules are forms of papules, but are larger and deeper.
Causes of Papules. From the latin papula, which means pimple, the word papule refers to small solid bumps on the skin. The can be differentiated from pustules by the fact that papules contain no pus. They usually present themselves in clusters, most frequently with rashes. They often itch.