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Answer: Ischemic white matter disease refers to small blood vessels in the brain that are clogging up a bit. This is usually not a serious condition unless the amount of small vessel disease gets to a moderate or severe degree.It is often caused by high blood pressure, diabetes, high cholesterol, or smoking.nswer: Ischemic white matter disease refers to small blood vessels in the brain that are clogging up a bit. This is usually not a serious condition unless the amount of small vessel disease gets to a moderate or severe degree.
Unlike Alzheimer's disease, which shrinks the hippocampus causing progressive memory loss, white matter disease is a more diffuse mind-robbing condition that targets small blood vessels deep within the brain's white matter. The disease hardens the tiny arteries, gradually restricting nutrients to white matter -- the connections between brain regions involved in executive abilities such as planning, organizing, problem-solving, and attention.