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Answer: Ischemic white matter disease refers to small blood vessels in the brain that are clogging up a bit. This is usually not a serious condition unless the amount of small vessel disease gets to a moderate or severe degree.It is often caused by high blood pressure, diabetes, high cholesterol, or smoking.nswer: Ischemic white matter disease refers to small blood vessels in the brain that are clogging up a bit. This is usually not a serious condition unless the amount of small vessel disease gets to a moderate or severe degree.
Gray and white matter. The brain of humans consists of gray matter and white matter. The gray matter contains the nerve cells. White matter-myelin. The white matter of the brain is composed of nerve fibers and myelin. The nerve fibers form the connections between the nerve cells. Myelin is a fatty sheath wrapped around nerve fibers. The myelin sheath has two functions: insulation and acceleration of impulse conduction.