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Alprazolam (Xanax) is a drug that relieves anxiety within about half an hour of oral intake. Most people who use Xanax say that a single dose kicks in 15- 30 minutes and its anti-anxiety effects last for a few hours.Taking it with food does not seem to affect its effects.Generally, a 0.25 mg dose is enough, but some variations among individuals may occur.ost people who use Xanax say that a single dose kicks in 15- 30 minutes and its anti-anxiety effects last for a few hours. Taking it with food does not seem to affect its effects. Generally, a 0.25 mg dose is enough, but some variations among individuals may occur.
25-07-2012 18:58. Hey guys, I have another post active but I wanted input into how long it should take for a Xanax to kick-in. I took 1mg about 6 hours ago and am yet to feel anything. Maybe a little sleepy but no more than usual.