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Causes of Menorrhagia. There are many possible causes of heavy menstrual bleeding. They include: 1  Hormonal imbalance, particularly in estrogen and progesterone; this is most common in adolescents who recently began their periods and women who are getting close to menopause.
See, can fibroids cause weight gain? 2. Heavy periods (menorrhagia) with blood clots as well as irregular periods (oligomenorrhea) or prolonged menstrual cycles which can lead to anemia. See, can fibroids cause heavy menstrual bleeding?