1 Roadmap for Quality Measurement in the Traditional Medicare Fee-for-Service Program [PDF, 3MB]. 2  Roadmap for Implementing Value Driven Healthcare in the Traditional Medicare Fee-for-Service Program [PDF, 3MB]. 3  Medicare Resource Use Measurement Plan [PDF, 3MB].
When a nerve signal, or impulse, reaches the ends of its axon, it has traveled as an action potential, or a pulse of electricity. However, there is no cellular continuity between one neuron and the next; there is a gap called synapse.
Unlike wires in your home, nerve cells do not touch, but come close together at synapses. At the synapse, the two nerve cells are separated by a tiny gap, or synaptic cleft. The sending neuron is called the presynaptic cell, while the receiving one is called the postsynaptic cell.Nerve cells send chemical messages with neurotransmitters in a one-way direction across the synapse from presynaptic cell to postsynaptic cell. Some get taken up by specific transporters on the presynaptic cell (reuptake). 2  In the presynaptic cell, MAO and COMT destroy the absorbed serotonin molecules. 3  This enables the nerve signal to be turned off and readies the synapse to receive another action potential.