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Causes of Menorrhagia. There are many possible causes of heavy menstrual bleeding. They include: 1  Hormonal imbalance, particularly in estrogen and progesterone; this is most common in adolescents who recently began their periods and women who are getting close to menopause.
The causes of menorrhagia can vary greatly between women, but some problems are commonly root causes of the unusually heavy bleeding. Such things as fibroids, low progesterone relative to estrogen (both common in perimenopause), polycystic ovary syndrome (PCOS), or other hormonal imbalances are usually to blame.he causes of menorrhagia can vary greatly between women, but some problems are commonly root causes of the unusually heavy bleeding. Such things as fibroids, low progesterone relative to estrogen (both common in perimenopause), polycystic ovary syndrome (PCOS), or other hormonal imbalances are usually to blame.