Province of Alicante. Alicante (Spanish: [aliËkante]), or Alacant (Valencian: [alaËkant]), is a province of eastern Spain, in the southern part of the Valencian Community. The second and third biggest cities in the Valencian Community (Alicante and Elche, respectively) are located in this province. Alicante is bordered by the provinces of Murcia on the southwest, Albacete on the west, Valencia on the north, and the Mediterranean Sea on the east. The province is named after its capital, the city of Alicante
Quinidine is a pharmaceutical agent that acts as a class I antiarrhythmic agent (Ia) in the heart. It is a stereoisomer of quinine, originally derived from the bark of the cinchona tree.
Quinine was the first effective Western treatment for malaria caused by Plasmodium falciparum, appearing in therapeutics in the 17th century.It remained the antimalarial drug of choice until the 1940s, when other drugs, such as chloroquine, that have fewer unpleasant side effects replaced it.uinine can, in therapeutic doses, cause cinchonism; in rare cases, it may even cause death (usually by pulmonary edema). The development of mild cinchonism is not a reason for stopping or interrupting quinine therapy, and the patient should be reassured.