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If you have a spinal or epidural procedure while you use Eliquis, tell your doctor at once if you notice any symptoms of nerve problems (eg, back pain, numbness [especially in the legs and feet], tingling, muscle weakness, paralysis, loss of bowel or bladder control).
The recommended dose of ELIQUIS is 2.5 mg taken orally twice daily. The initial dose. should be taken 12 to 24 hours after surgery. â¢ In patients undergoing hip replacement surgery, the recommended duration of. treatment is 35 days. â¢ In patients undergoing knee replacement surgery, the recommended duration of.