Carbapenems can only be given through an intravenous drip, which usually does not cause irritation at the injection site. If you have a severe allergy to penicillin, you generally should not be given a carbapenem. However, many patients with a mild or moderate allergy can tolerate carbapenems.
Alpha-1 adrenergic agonists. Alpha-1 adrenergic agonists stimulate alpha-1 receptors coupled to G proteins and phospholipase C. They can be classified in two groups: those which do not cross the blood-brain barrier and have peripheral effects and those which penetrate into the brain and have mainly central effects. Alpha-1 agonists with peripheral effects.
4. An agonist ties to a receptor site and causes a response whereas an antagonist works against the drug and blocks the response. 5. Agonists are also chemicals or reactions, which help in binding and also altering the function of the activity of receptors.