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A: If your room temperature goes above about 80 degrees Fahrenheit, you would be safer to keep your insulin in the refrigerator. Q: I use an insulin pen. I have heard I should keep my pen at room temperature for only two weeks. But insulin in vials can be kept at room temperature up to 28 days.
Storing Insulin and Prefilling Syringes - Topic Overview. Insulin can become damaged and ineffective if it is not stored properly. Unopened insulin that is packaged in small glass bottles (vials) should be stored in the refrigerator.