Examples. 1  Contract research businesses such as Covance conduct many clinical trials and focus on improving efficiency at every step of the process. Eli Lilly Signs R&D Pact With Covance.
Excessive running or walking. Over-use of the thigh and hip muscles leading to the muscle weakness and excessive pressure in kneecap leading to the pain in knee. Wearing wrong shoes causes excessive stress on ligament, cartilage and knee cap resulting in early wear and tear.
Experts disagree on whether tight, high-heeled or too-narrow shoes cause bunions or whether footwear simply contributes to bunion development. Bunions might be associated with certain types of arthritis, particularly inflammatory types, such as rheumatoid arthritis.