Examples. 1  Contract research businesses such as Covance conduct many clinical trials and focus on improving efficiency at every step of the process. Eli Lilly Signs R&D Pact With Covance.
Excessive running or walking. Over-use of the thigh and hip muscles leading to the muscle weakness and excessive pressure in kneecap leading to the pain in knee. Wearing wrong shoes causes excessive stress on ligament, cartilage and knee cap resulting in early wear and tear.
Women and Bunions. Women are more frequently affected with bunions because of tight, pointed, flat or high-heeled shoes. Unsupportive shoes place excessive pressure through the joint causing the bunion deformity. Tight shoes aggravate the condition. Wearing high-heeled shoes is especially stressful on the joints of the foot.