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A: If your room temperature goes above about 80 degrees Fahrenheit, you would be safer to keep your insulin in the refrigerator. Q: I use an insulin pen. I have heard I should keep my pen at room temperature for only two weeks. But insulin in vials can be kept at room temperature up to 28 days.
Insulin loses it's effectiveness and potency at room temperature. Unopened bottles or pen cartridges should be kept in the fridge. Once a bottle or pen cartridge is open and in use, it can be kept at room temperature until it's either used up or 30 days has passed, whichever comes first. Thirty days is the maximum time that insulin can be kept at room temperature.