1 Low zinc intake seems to be linked to lower bone mass. 2  Taking a zinc supplement in combination with copper, manganese, and calcium might also decrease bone loss in postmenopausal women. 3  Treating an inherited disorder called acrodermatitis enteropathica. 4  Leprosy, when used with other medications.
Creatinine: A chemical waste molecule that is generated from muscle metabolism. Creatinine is produced from creatine, a molecule of major importance for energy production in muscles. Approximately 2% of the body's creatine is converted to creatinine every day.
Calorie restriction (CR), or caloric restriction, is a dietary regimen that is based on low calorie intake. Low can be defined relative to the subject's previous intake before intentionally restricting calories, or relative to an average person of similar body type.