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But different painkillers work better for different types of pain. For pain associated with inflammation, such as back pain or headaches, paracetamol and anti-inflammatory painkillers work best.If the pain is caused by sensitive or damaged nerves, as is the case with shingles or sciatica, it is usually treated with tablets that are also used for epilepsy and depression.ach of these tablets can also be used to treat pain caused by nerve sensitivity or nerve damage, such as shingles, diabetes nerve pain and sciatica. You donât have to have depression or epilepsy for these tablets to help your nerve pain. Amitriptyline and gabapentin both have to be prescribed by a GP.
In fact, many of the following nine nerve pain relief treatments are used in combination for greater success. For acute nerve pain, doctors often suggest the most powerful prescription option availableâopioid painkillers. These not only work fast at providing pain relief, but also often work when lower dose treatments fail to quell discomfort.