1 Cover tightly. 2  Preheat oven to 425 degrees F for 15 minutes. 3  Place the roast in the oven and immediately reduce the temperature down to 200 degrees F. 4  Roast for about 4 hours or until the meat is falling-apart tender (cooking time will vary depending on the size of the roast).
intrinsic. adj. 1. of or relating to the essential nature of a thing; inherent. 2. (Anatomy) anatomy situated within or peculiar to a part: intrinsic muscles. [C15: from Late Latin intrinsecus from Latin, inwardly, from intrÄ within + secus alongside; related to sequÄ« to follow].
intrinsic muscles. Definitions: 1. muscles fully contained (origin, belly, and insertion) within the structure under consideration. For example, the interossei and lumbrical muscles are intrinsic muscles of the hand.The definition information for intrinsic muscles is provided by Stedman's.You can search our medical dictionary here.efinitions: 1. muscles fully contained (origin, belly, and insertion) within the structure under consideration. For example, the interossei and lumbrical muscles are intrinsic muscles of the hand. The definition information for intrinsic muscles is provided by Stedman's.