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Macules may be of. any size or color. A macule greater than 2 cm. in diameter is called a patch. Ex: cafÃ©-au-lait: Mongolian spot; freckle. 2. Papule: Papule is a solid, elevated lesion with no visible fluid which may be up to Â½. cm. in diameter. The elevation may be accounted for by metabolic deposits, infiltrates, or hyperplasia of cellular elements, etc. A papulosquamous lesion is a papule with desquamation (scaling). 3. Nodules: Nodules are forms of papules, but are larger and deeper.
Papules are a form of acne vulgaris that appear as small bumps on the face. The bumps reveal no visible pores as in blackheads, and they are not white like whiteheads. Instead, they are closed, red and surrounded by skin inflammation. The best acne treatment for papules typically resembles the best acne treatment for pustules, whiteheads, and blackheads, but it's important to remember that squeezing papules is not the right way to get rid of acne (as tempting as it may sometimes be).