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If you have a spinal or epidural procedure while you use Eliquis, tell your doctor at once if you notice any symptoms of nerve problems (eg, back pain, numbness [especially in the legs and feet], tingling, muscle weakness, paralysis, loss of bowel or bladder control).
1 ELIQUIS can cause a skin rash or severe allergic reaction. 2  Call your doctor or get medical help right away if you have any of the following symptoms: 3  chest pain or tightness. 4  swelling of your face or tongue. 5  trouble breathing or wheezing. 6  feeling dizzy or faint.