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The time it takes for the body to eliminate one half of a caffeine dose is normally between 3 to 12 hours. It is called the half-life of caffeine. Several factors can shorten or lengthen the half life of caffeine. Smoking, medications and diseases are some factors.
Effects on the Body: Hormones- You can feel the effects of caffeine in your system within a few minutes of ingesting it, and it stays on your system for many hoursâit has a half-life of four to six hours in your body. While in your body, caffeine affects the following hormones: