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1 If you are coming off a high dose of Subutex or Suboxone, cold turkey, the acute phase may not creep in until around the week mark. 2  Usually after 12 to 14 days you will see light at the end of the tunnel but some lingering withdrawals will last for up to six weeks, although these are more of a burden than a debility. Both Subutex and Suboxone have a 36 hour mean half-life which means half the drug will be out your system in 36 hours but this does not mean the other half will be gone 36 hours after this.
You will know it is working when you will feel suppression from using the opioid. Coming back to how long does suboxone block opiates; the half life of this drug is 37 hours and is excreted out via urine. Having a half life of 37 hours means that when 37 hours are done, there will be only 50% amount left in the body.With every dosage there will be an increment of 50%.So if we do the math, the time for how long does suboxone block opiates is about a week!ame is the case with Suboxone. If you do not know that how long does it take for the suboxone to work, how to take it and how long does suboxone block opiates then you need to carry on reading this article without taking any doses of it.