People who take opioids for pain relief for extended periods of time may need higher doses to ease their pain. They may develop tolerance to the drug and experience withdrawal symptoms if the medication is abruptly stopped. They become physically dependent on the drug.
Antibiotics most likely to cause C. diff infections are clindamycin, amoxicillin, ampicillin, and cephalosporins, and to a lesser extent, penicillin, erythromycin, and quinolones.
C. DIFFICILE RISK FACTORS. A number of factors can increase a person's risk of becoming infected with C. difficile: Current or recent antibiotic use â Certain antibiotics increase the risk of becoming infected with C. difficile more than others .