The drugs they looked at were heroin, cannabis, nicotine, alcohol, methadone, amphetamine and MDMA. As described in Scientific Reports, they found that, at the level of individual use, four substances were classified as high risk: alcohol, nicotine, cocaine and heroin.
Prepping the brisket. Start with a brisket in the 10- to 12-pound range, which is just the right size to fit on the grill. Trim off the excess top fat or âfat cap,â but leave a Â¼-thick layer of fat to keep the meat moist during the long cooking process. Sprinkle on a few tablespoons of rub, spreading it evenly on both sides of the brisket.
Remove from the grill, cover the brisket with foil tightly sealed to the pan, and let the brisket sit for 45-60 minutes, during which time it will re-absorb a lot of the juices and also undergo tenderization. This resting period is very important for juicy, tender brisket.