Stickler syndrome or hereditary progressive arthro-ophthalmopathy[1] (ORPHA828) is a connective tissue disorder affecting about 1/7,500 to 1/9,000 newborns[2]. It is characterized by ocular, skeletal, orofacial, and auditory abnormalities.
Mayflower Park â Downtown Seattle Hotel. Mayflower Park â downtown Seattle Hotel â Welcome to the historic Mayflower Park Hotel. Ideally located in thriving downtown Seattle, the Mayflower Park is in the heart of the city. Built in 1927, the classic Mayflower Park Hotel has been lovingly restored with crystal chandeliers, gleaming brass and period antiques that offer an inviting European elegance to this historic Seattle hotel.
Signing the covenant were 41 of the ship's 101 passengers, while the Mayflower was anchored in what is now Provincetown Harbor within the hook at the northern tip of Cape Cod.