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n. Any of numerous olfactory filaments in the olfactory portion of the nasal mucosa that enter the olfactory bulb, where they terminate in synaptic contact with mitral cells, tufted cells, and granule cells. Also called first cranial nerve.
The olfactory nerve is sensory in nature and originates on the olfactory mucosa in the upper part of the nasal cavity. From the olfactory mucosa, the nerve (actually many small nerve fascicles) travels up through the cribriform plate of the ethmoid bone to reach the surface of the brain.esions to the olfactory nerve can occur because of blunt trauma, such as coup-contra-coup damage, meningitis, and tumors of the frontal lobe. They often lead to a reduced ability to taste and smell. However, lesions of the olfactory nerve do not lead to a reduced ability to sense pain from the nasal epithelium.