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Alprazolam (Xanax) is a drug that relieves anxiety within about half an hour of oral intake. Most people who use Xanax say that a single dose kicks in 15- 30 minutes and its anti-anxiety effects last for a few hours.Taking it with food does not seem to affect its effects.Generally, a 0.25 mg dose is enough, but some variations among individuals may occur.ost people who use Xanax say that a single dose kicks in 15- 30 minutes and its anti-anxiety effects last for a few hours. Taking it with food does not seem to affect its effects. Generally, a 0.25 mg dose is enough, but some variations among individuals may occur.
A. Alprazolam (Xanax) is an anxiety-relieving medicine that starts to work within about an hour after taking the pill. The level of drug reaches a peak in the bloodstream after one to two hours, and its felt effects last on average about 5 hours.owever, Xanax remains in the bloodstream long after its anti-anxiety effects have worn off. Xanaxâs average half-life is 11 hours. This means that it takes an average of 11 hours for the body to eliminate half the Xanax dose.