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What is epigastric distress? A: According to Dictionary.com the word epigastric is used to describe the upper middle part of the abdomen, the area above the navel and below the breast. Epigastric distress, therefore, simply describes pain or discomfort in the upper part of the abdomen. More than 25 different conditions can cause this type of discomfort, according to MedicineNet.
Shares & Saves. Save. Epigastric pain is an ache or soreness in the upper and middle portions of the abdomen, just below the sternum. There are a variety of causes for abdominal pain, and it is often difficult to pinpoint the exact cause without extensive testing.Gastroesophageal reflux disease, lactose intolerance, gallstones and pancreatitis are a few of the most common causes of epigastric pain.here are a variety of causes for abdominal pain, and it is often difficult to pinpoint the exact cause without extensive testing. Gastroesophageal reflux disease, lactose intolerance, gallstones and pancreatitis are a few of the most common causes of epigastric pain.