The drugs they looked at were heroin, cannabis, nicotine, alcohol, methadone, amphetamine and MDMA. As described in Scientific Reports, they found that, at the level of individual use, four substances were classified as high risk: alcohol, nicotine, cocaine and heroin.
Prepping the brisket. Start with a brisket in the 10- to 12-pound range, which is just the right size to fit on the grill. Trim off the excess top fat or âfat cap,â but leave a Â¼-thick layer of fat to keep the meat moist during the long cooking process. Sprinkle on a few tablespoons of rub, spreading it evenly on both sides of the brisket.
Instructions. 1  Trim meat side of brisket so there is almost no fat. 2  Trim fat cap down to about 1/4 inch thickness. 3  Marinade brisket overnight.  Remove from marinade, pat dry, and sprinkle a heavy coat of rub all 1  over. Smoke brisket for at least 4 hours using a mix of hickory and fruit woods. If possible, place an aluminum pan underneath the brisket to catch the delicious natural juices. Place brisket in a pan with natural juices and a cup of the reserved marinade. Cover and cook until internal temp hits at least 200.