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1 If you are coming off a high dose of Subutex or Suboxone, cold turkey, the acute phase may not creep in until around the week mark. 2  Usually after 12 to 14 days you will see light at the end of the tunnel but some lingering withdrawals will last for up to six weeks, although these are more of a burden than a debility. Both Subutex and Suboxone have a 36 hour mean half-life which means half the drug will be out your system in 36 hours but this does not mean the other half will be gone 36 hours after this.
HK171. I took my last dose of suboxone 5 days ago. Symptoms started on day 2...similar to the symptoms that I experienced coming off of Percocet, oxycontin, dilauded, etc, but not as bad. Still, I've missed two days of work, can't sleep, muscles are achy...feels like my bones are growing and my skin is shrinking. was on 24 mg for 11 months and tapered out to 2mg before stopping. Day 2 also started the fun for me as well in contrast to what my doctor advised me. It took 7 days before I could lay still in bed and get 5 hours of sleep.