So what is it, exactly? The rotator cuff is a group of four tendons and muscles that converge around the shoulder joint at the top of the humerus, the upper arm bone above the elbow. Together, they form a ''cuff'' that both holds your arm in place and allows it to move in different directions.hile your shoulder is one of your most mobile joints, it's also somewhat weak. Too much stress -- or too many fastballs -- can cause partial tears and swelling in the tendons of the rotator cuff. Abrupt stress may even cause one of the tendons to pull away from the bone or tear in the middle of the tendon.
A gene mutation is a permanent alteration in the DNA sequence that makes up a gene, such that the sequence differs from what is found in most people.Mutations range in size; they can affect anywhere from a single DNA building block (base pair) to a large segment of a chromosome that includes multiple genes. gene mutation is a permanent alteration in the DNA sequence that makes up a gene, such that the sequence differs from what is found in most people.
The word mutation means a change in the genetic composition of a cell. Mutations can be divided into two main groups. The first group is gene mutations. These are chemical changes in the DNA [DNA: The material inside the nucleus of cells, carrying genetic information.DNA stands for Deoxyribonucleic Acid.] of the cell. A gene mutation is a change in the order of bases on a strand of DNA.riginal gene structure. This shows the normal order of the bases for one of the strands in the area highlighted in the DNA molecule. Only one of the strands of DNA is involved in protein synthesis. A change from the normal order of bases leads to different types of gene mutation.