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Signs and symptoms of Leiomyosarcoma. People with early leiomyosarcoma often do not have any symptoms. Most leiomyosarcomas are diagnosed after a person develops symptoms. These may include: 1  a lump or swelling. 2  abdominal discomfort or bloatedness.3  swelling or pain in any area of the body.eiomyosarcoma. A leiomyosarcoma belongs to a group of rare cancers called soft tissue sarcomas. Sarcomas are cancers that develop in the supporting or connective tissues of the body, such as muscle, fat, nerves, blood vessels, bone and cartilage.
From Wikipedia, the free encyclopedia. A leiomyoma (plural leiomyomas or leiomyomata) (leio- + myo- + -oma, smooth-muscle tumor) is a benign smooth muscle neoplasm that very rarely becomes cancer (0.1%). They can occur in any organ, but the most common forms occur in the uterus, small bowel, and the esophagus.Leiomyoma enucleated from a uterus.s other leiomyomata, they are benign, but may lead to excessive menstrual bleeding (menorrhagia), often cause anemia and may lead to infertility. A rare form of these tumors is uterine lipoleiomyoma-benign tumors consisting of a mixture of adipocytes and smooth muscle cells.