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The lactate threshold (LT) (or lactate inflection point (LIP) or anaerobic threshold (AT)) is the exercise intensity at which lactate (more specifically, lactic acid) starts to accumulate in the blood stream.
Purpose: Increased bloodâbrain barrier (BBB) permeability is radiologically detectable in regions affected by drug-resistant epileptogenic lesions. Brain penetration of antiepileptic drugs (AEDs) may be affected by BBB damage.ack of significant effect of bloodâbrain barrier disruption (BBBD) on brain water content and modest effect of parenchymal edema on drug uptake. (A) Calibration curve for the determination of water content and determination of water brain content ...