Stickler syndrome or hereditary progressive arthro-ophthalmopathy[1] (ORPHA828) is a connective tissue disorder affecting about 1/7,500 to 1/9,000 newborns[2]. It is characterized by ocular, skeletal, orofacial, and auditory abnormalities.
Mayflower Park â Downtown Seattle Hotel. Mayflower Park â downtown Seattle Hotel â Welcome to the historic Mayflower Park Hotel. Ideally located in thriving downtown Seattle, the Mayflower Park is in the heart of the city. Built in 1927, the classic Mayflower Park Hotel has been lovingly restored with crystal chandeliers, gleaming brass and period antiques that offer an inviting European elegance to this historic Seattle hotel.
Highlights. 1  Book a stay at our centrally located hotel in Downtown Phoenix, AZ. 2  The planet-friendly light rail is just outside our front doors. 3  Our Downtown Phoenix hotel is just blocks from Comerica Theatre, known for hosting a variety of world-class concerts and comedy acts.