Stickler syndrome or hereditary progressive arthro-ophthalmopathy[1] (ORPHA828) is a connective tissue disorder affecting about 1/7,500 to 1/9,000 newborns[2]. It is characterized by ocular, skeletal, orofacial, and auditory abnormalities.
Mayflower Park â Downtown Seattle Hotel. Mayflower Park â downtown Seattle Hotel â Welcome to the historic Mayflower Park Hotel. Ideally located in thriving downtown Seattle, the Mayflower Park is in the heart of the city. Built in 1927, the classic Mayflower Park Hotel has been lovingly restored with crystal chandeliers, gleaming brass and period antiques that offer an inviting European elegance to this historic Seattle hotel.
History of Plymouth Rock The Mayflower arrived in Plymouth Harbor in 1620, after first stopping near today's Provincetown. According to oral tradition, Plymouth Rock was the site where William Bradford and other Pilgrims first set foot on land.