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Alprazolam (Xanax) is a drug that relieves anxiety within about half an hour of oral intake. Most people who use Xanax say that a single dose kicks in 15- 30 minutes and its anti-anxiety effects last for a few hours.Taking it with food does not seem to affect its effects.Generally, a 0.25 mg dose is enough, but some variations among individuals may occur.ost people who use Xanax say that a single dose kicks in 15- 30 minutes and its anti-anxiety effects last for a few hours. Taking it with food does not seem to affect its effects. Generally, a 0.25 mg dose is enough, but some variations among individuals may occur.
Peak levels and half life of Xanax. Xanax is absorbed quickly in the body and reaches its peak levels in the blood within one or two hours. These plasma blood levels vary depending on the dose taken, but range from 8-37 ng/mL. The half life of Xanax in healthy adults averages 11 hours. In elderly subjects the half life of Xanax is higher, about 16 hours.