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Answer: Ischemic white matter disease refers to small blood vessels in the brain that are clogging up a bit. This is usually not a serious condition unless the amount of small vessel disease gets to a moderate or severe degree.It is often caused by high blood pressure, diabetes, high cholesterol, or smoking.nswer: Ischemic white matter disease refers to small blood vessels in the brain that are clogging up a bit. This is usually not a serious condition unless the amount of small vessel disease gets to a moderate or severe degree.
White matter disease. White matter disease also offers an insight into the importance of white matter in the brain. White matter disease targets small blood vessels deep inside white matter in the brain.In turn, these tiny arteries are then hardened, making it difficult for nutrients to access cells in the white matter.hite matter disease targets small blood vessels deep inside white matter in the brain. In turn, these tiny arteries are then hardened, making it difficult for nutrients to access cells in the white matter.