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Macules may be of. any size or color. A macule greater than 2 cm. in diameter is called a patch. Ex: cafÃ©-au-lait: Mongolian spot; freckle. 2. Papule: Papule is a solid, elevated lesion with no visible fluid which may be up to Â½. cm. in diameter. The elevation may be accounted for by metabolic deposits, infiltrates, or hyperplasia of cellular elements, etc. A papulosquamous lesion is a papule with desquamation (scaling). 3. Nodules: Nodules are forms of papules, but are larger and deeper.
Picture 1 â Pompholyx Image. Source â avicenna. The term Pomphlolyx is a Greek derivative which means a bubble. It is a kind of skin eczema that is characterized by the occurrence of small itchy blisters on the hands and the feet. It also causes the inflammation and the drying up of the skin, thereby causing irritation.