Mix the lemon juice, butter, salt and garlic powder in a bowl. Top the fillets with the mixture and add the paprika, oregano and capers. Preheat oven to 400 degrees Fahrenheit and bake the fish for 20 minutes to 30 minutes.lace the baking dish in the oven and cook for 30 minutes. Serve immediately. Easy Baked Tilapia. For this recipe, you need four tilapia fillets, three tablespoons melted butter, three tablespoons lemon juice, 1 Â½ teaspoons garlic powder and 1/8 teaspoon salt.
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