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A: If your room temperature goes above about 80 degrees Fahrenheit, you would be safer to keep your insulin in the refrigerator. Q: I use an insulin pen. I have heard I should keep my pen at room temperature for only two weeks. But insulin in vials can be kept at room temperature up to 28 days.
Keeping Insulin Cool. Firstly, check if you do need to keep your insulin cool. While itâs best to be prepared, insulin can handle short trips when not refrigerated. Itâs the exposure to extremes of heat that can deactivate it. Keep insulin in hand luggage if you are taking a plane - if it goes in the cargo hold with the luggage it might freeze which will deactivate it.