People who take opioids for pain relief for extended periods of time may need higher doses to ease their pain. They may develop tolerance to the drug and experience withdrawal symptoms if the medication is abruptly stopped. They become physically dependent on the drug.
Antibiotics most likely to cause C. diff infections are clindamycin, amoxicillin, ampicillin, and cephalosporins, and to a lesser extent, penicillin, erythromycin, and quinolones.
C. diff (Clostridium Difficile) is a bacterial infection of the colon. It is caused by an imbalance in the bacterial levels that normally exist in the colon. The imbalance could be a result of heavy antibiotic usage, which can disrupt the bacterial levels that are found normally in the colon.