Itâs happened before. An otherwise healthy 29-year-old mother of three made news in 2014 when she died of the flu and, according to data from the [Centers for Disease Control and Prevention (CDC), between 3,000 and 49,000 Americans die of the flu each year.
Other causes of nosebleeds include: 1  Acute sinusitis. 2  Allergies. 3  Aspirin use. 4  Bleeding disorders, such as hemophilia. 5  Blood thinners (anticoagulants), such as warfarin and heparin. 6  Chemical irritants, such as ammonia. 7  Chronic sinusitis. 8  Cocaine use.
Reactions included anaphylaxis (the most severe type of allergic reaction), acute asthma attacks, severe urticaria (hives) and swelling. Four were hospitalized and Echinacea was the only implicated medication in 15 cases. Over half were known to have other allergies.