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A diaphragmatic hernia that occurs through this opening is called a hiatus hernia. The cause of hiatus hernia is usually unknown, but it may be caused by stretching of the bands of tissue that are attached between the esophagus and diaphragm at the hiatus. The condition is more common among people who are older than 50, who are overweight (particularly women), or who smoke.
Infections â Infections in the esophagus also can cause esophagitis. They usually occur in people with a weak immune system. Esophagitis from infections is common in people who have HIV infection, use steroid medicines long-term, have had organ transplants, or have been treated with chemotherapy for cancer. Only a few types of infection are common in the esophagus, such as: yeast.