Peripheral artery disease (P.A.D.) is a disease in which plaque builds up in the arteries that carry blood to your head, organs, and limbs. Plaque is made up of fat, cholesterol, calcium, fibrous tissue, and other substances in the blood.
Painless swelling may affect both legs and may include the calves or even the thighs. The effect of gravity makes the swelling most noticeable in the lower part of the body. Foot, leg, and ankle swelling is common when the person also: Is overweight.
Baker's Cyst: A Baker's cyst is not a true cyst. Rather, it is a collection of knee-joint fluid that has pooled in the back of the knee. When excessive amounts of fluid accumulate, it can cause pain in the back of the leg. Occasionally, the Baker's cyst will rupture, causing the fluid to enter the calf region. Blood Clots: A blood clot needs to be considered as a cause of calf pain, especially when the calf pain is not the immediate result of an injury. Blood clots can form in the deep veins of the leg, causing a blockage in circulation. This may cause swelling and pain in the calf.