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The leaves become bitter and the plants begin to bolt as the stem elongates into a tall bloom stalk. Leaf lettuce varieties take about 40 days from seeding to harvest while head types may take 70 days. This is another reason the head types are more of a challenge. To get more from your garden space, consider interplanting your lettuce with slower maturing crops.
Harvest leaves from the outside of your lettuce, without cutting into the central growth, after about 40 to 50 days have passed. Continuously harvest from each plant, as needed, by simply bending an outer leaf downward and cutting the leaf off 1 to 2 inches above the soil. Look for signs of insect damage (chewed leaves, small holes in leaves, brown or yellow spots) as well as that of hungry mammals (large bites or rips in the leaves).