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Quick Answer. According to Good Housekeeping, brands of toilet paper that dissolve especially quickly include Scott 1000 one-ply, Target Up & Up two-ply, Seventh Generation two-ply, Scott Naturals two-ply and White Cloud Ultra three-ply. Contrary to expectations, one-ply toilet paper did not dissolve fastest in Good Housekeeping's tests, as of 2014.
Besides orientation, toilet paper manufacturers and survey authors have studied other private practices around toilet paper: how much is used; whether it is torn off with one hand or two; whether it is torn off right-to-left or left-to-right; and whether it is crumpled or folded before use.