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Lithium has been used for over half a century for the treatment of bipolar disorder as the archetypal mood stabilizer, and has a wealth of empirical evidence supporting its efficacy in this role. Despite this, the specific mechanisms by which lithium exerts its mood-stabilizing effects are not well understood.
Lithium is a drug used by doctors and psychiatrists to treat patients with manic-depressive disorder, also known as bipolar depression. This is a very volatile mental condition, and Lithium often helps regulate the mood of the patient. Mike Tyson is a famous lithium patient.