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The cause of itai-itai disease was determined to be cadmium poisoning in the drinking water from the Jinzugawa River basin. The source of cadmium was discovered to be from Mitsui Mining and Smelting Company. Mitsui Mining began to discharge cadmium into the Jinzugawa River in 1910.
toxic effects and lethality can occur. occupational settings in which workers are exposed to toxic metals. 1. power plants that burn coal, metal smelters, industrial facilities emit cadmium and arsenic. 2. incinerators constructed to dispose of wastes emit cadmium and mercury. 3. gold mines release arsenic, cinnabar mines release mercury. methods for prevention of exposure to toxic metals.