Report Abuse. Yes, it is legally binding, providing that other statutes weren't broken in obtaining the IOU or in the agreement itself. If you threatened someone to get them to sign it, it's not legal. If it's for an illegal enterprise, it is not legal. If you are charging excessive interest, again, not legal.eport Abuse. Yes, it is legally binding, providing that other statutes weren't broken in obtaining the IOU or in the agreement itself. If you threatened someone to get them to sign it, it's not legal. If it's for an illegal enterprise, it is not legal. If you are charging excessive interest, again, not legal.
In the US (~320 million people), this amounts to about 320-500 patients at any one time. Acquired hemophilia can occur in association with other underlying conditions that involve the immune system, like cancer, other autoimmune diseases, pregnancy or even the use of certain medications (shown in pie chart below).
People with hemophilia A do not have enough clotting factor VIII. Most people with hemophilia A have severe disease as manifested by bleeding into the large joints such as the knees or hips. . Hemophilia B is also known as Christmas disease. It is caused by a deficiency in clotting factor IX. It can be mild, moderate or severe. Hemophilia C is also called factor XI deficiency. It is uncommon in the United States. Hemophilia C is caused by a deficiency in clotting factor XI.