Drug therapy is warranted for many dogs with liver disease. Glucocorticoids (âsteroidsâ) have been used to prolong survival times in dogs with liver disease due to their anti-inflammatory and immunosuppressive properties, although their use and appropriate dosage protocols are somewhat controversial.
chiasma. pl. chiasmata [L., Gr.] chiasm; in genetics, the points at which members of a chromosome pair are in contact during the prophase of meiosis and because of which recombination, or crossing over, occurs on separation.
Chiasma (genetics) In genetics, a chiasma (pl. chiasmata) is the point of contact, the physical link, between two (non-sister) chromatids belonging to homologous chromosomes. At a given chiasma, an exchange of genetic material can occur between both chromatids, what is called a chromosomal crossover, but this is much more frequent during meiosis than mitosis. In meiosis, absence of a chiasma usually result in improper chromosomal segregation and aneuploidy.