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Mar 13, '09. The headache comes because Morphine produces vasodilation. This is why we give Morphine for chest pain patients. The vasodilation is great to reduce constriction due to angina, but it causes headaches due to the vasodilation.
Another time-release version is Kadian. The other common oral drug that contains morphine is MS IR, which is the immediate-release version. Morphine is more commonly given in intravenious form, especially in a hospital setting, especially in a time-drip release form.But the other drugs listed above do NOT contain morphine.OxyContin, Oxydone, Endone and another drug, OxyIR contain oxycodone, not morphine.orphine is more commonly given in intravenious form, especially in a hospital setting, especially in a time-drip release form. But the other drugs listed above do NOT contain morphine. OxyContin, Oxydone, Endone and another drug, OxyIR contain oxycodone, not morphine.