Generally, anisocoria is caused by impaired dilation (a sympathetic response) or impaired constriction (a parasympathetic response) of pupils. An injury or lesion in either pathway may result in changes in pupil size.
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Medications: i would not take motrin with lisinopril. motrin can affect kidney function, and lisinopril modulates kidney function to regulate blood pressure. you can induce a mild kidney injury depending on how much motrin you take a day. i would use the muscle relaxer, and use tylenol (acetaminophen) extra strength instead.