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Leukotriene modifier. Montelukast (Singulair) can ease both allergy and asthma symptoms. Called a leukotriene modifier, this daily pill helps control immune system chemicals released during an allergic reaction. In rare cases, montelukast has been linked to psychological reactions, including suicidal thinking.
Class Summary. Alternative to oral antihistamine to treat allergic rhinitis. One of the leukotriene receptor antagonists, montelukast (Singulair), has been approved in the United States for treatment of seasonal and perennial allergic rhinitis.When used as single agent, produces modest improvement in allergic rhinitis symptoms.