Not enough sleep or disruptions to the sleep-wake cycle (such as those that may occur with shift work or travelling to a different time zone) cause the physiological state known as fatigue. Staying awake for 24 hours leads to a reduced hand-to-eye coordination that is similar to having a blood alcohol content of 0.1.
There are 13 hearts in a standard 52 card deck. There are also 13 diamonds, 13 spades and 13 clubs.
The number of ways to have two hearts and one other card that is not a heart is $({}_{13} C_2)({}_{39} C_1) = 78 \times 39 = 3328$. In this computation, we chose 2 of the 13 available hearts, and one of the other 39 cards to make up the hand.