Report Abuse. Yes, it is legally binding, providing that other statutes weren't broken in obtaining the IOU or in the agreement itself. If you threatened someone to get them to sign it, it's not legal. If it's for an illegal enterprise, it is not legal. If you are charging excessive interest, again, not legal.eport Abuse. Yes, it is legally binding, providing that other statutes weren't broken in obtaining the IOU or in the agreement itself. If you threatened someone to get them to sign it, it's not legal. If it's for an illegal enterprise, it is not legal. If you are charging excessive interest, again, not legal.
In the US (~320 million people), this amounts to about 320-500 patients at any one time. Acquired hemophilia can occur in association with other underlying conditions that involve the immune system, like cancer, other autoimmune diseases, pregnancy or even the use of certain medications (shown in pie chart below).
A female with one affected X chromosome is a carrier of hemophilia. Sometimes a female who is a carrier can have symptoms of hemophilia. In addition, she can pass the affected X chromosome with the clotting factor gene mutation on to her children.Learn more about the inheritance pattern for hemophilia.here are several different types of hemophilia. The following two are the most common: 1  Hemophilia A (Classic Hemophilia). 2  This type is caused by a lack or decrease of clotting factor VIII. 3  Hemophilia B (Christmas Disease). 4  This type is caused by a lack or decrease of clotting factor IX.