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Hepatitis B and infants In general, the hepatitis B vaccine schedule is flexible and can vary as long as ALL of the following minimum intervals are met: at least 4 weeks are needed between doses #1 and #2, at least 8 weeks between doses #2 and #3, and at least 16 weeks between doses #1 and #3.horter than the recommended interval, the minimum interval is the shortest time between two doses of a vaccine series in which an adequate immune response to the second dose can be expected. The concern is that a dose given too soon after the previous dose may reduce the response.
A vaccination for both hepatitis A and B can be given to those ages 18 and older; however, this vaccination is administered in three doses over six months. A hepatitis A vaccination consists of inactive virus; people 1 year old or older can receive the vaccine. It is highly effective.The first dose protects your body (for the short-term) in an estimated two to four weeks.Once you receive the second dose (about six to 12 months after the first), the vaccine should work for at least 20 years.Studies estimate, however, that the vaccine may last over the course of your lifetime.nce you receive the second dose (about six to 12 months after the first), the vaccine should work for at least 20 years. Studies estimate, however, that the vaccine may last over the course of your lifetime.