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Addiction is defined as a chronic, relapsing brain disease that is characterized by compulsive drug seeking and use, despite harmful consequences. â  It is considered a brain disease because drugs change the brainâthey change its structure and how it works.
Addiction is defined as a chronic, relapsing brain disease that is characterized by compulsive drug seeking and use, despite harmful consequences.â  It is considered a brain disease because drugs change the brainâthey change its structure and how it works.. Volkow and H. Schelbert. Addiction is a lot like other diseases, such as heart disease. Both disrupt the normal, healthy functioning of the underlying organ, have serious harmful consequences, and are preventable and treatable, but if left untreated, can last a lifetime.