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Leukotriene modifier. Montelukast (Singulair) can ease both allergy and asthma symptoms. Called a leukotriene modifier, this daily pill helps control immune system chemicals released during an allergic reaction. In rare cases, montelukast has been linked to psychological reactions, including suicidal thinking.
In clinical studies, Singulair (monteleukast) and other leukotriene modifiers: 1  Provide clinical benefit when added to an inhaled steroid. 2  Have allowed for a lower dose of an inhaled steroid. 3  Improve FEV1.  Decrease nocturnal asthma 1  symptoms. Improved quality of life.