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The cause of itai-itai disease was determined to be cadmium poisoning in the drinking water from the Jinzugawa River basin. The source of cadmium was discovered to be from Mitsui Mining and Smelting Company. Mitsui Mining began to discharge cadmium into the Jinzugawa River in 1910.
Causes of red itchy bumps. Red itchy bumps all over the body can result from various disease conditions like: Scabies - This is a parasitic infection caused by Sarcoptes scabiei. It is contagious and is characterized by extreme itchiness on the skin. The burrow tracks of the mite appear to be similar to the bites of a typical mosquito.