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A person should try clozapine for at least four to six weeks. Some symptoms, such as hallucinations, anxiety, paranoia, and bizarre behavior, should improve within that time; other symptoms may take longer. Additional improvements may be noticed over six to twelve months.here have been no confirmed cases of TD directly caused by clozapine alone, but patients should be regularly monitored for the development of TD. While agranulocytosis usually occurs most commonly within the first 4â6 months of treatment, you are at risk of this rare adverse effect for as long as you take clozapine.
Clozapine can also cause seizures, especially in higher doses. Let your doctor or pharmacist know if you have ever had seizures. While taking this medication, avoid driving or other activities during which a sudden loss of consciousness could be dangerous (e.g., operating heavy machinery, swimming).efore taking clozapine, tell your doctor or pharmacist if you are allergic to it or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.