Inhibition of Adenylate Cyclase: The muscarinic receptor, through interaction with an inhibitory GTP-binding protein, acts to inhibit adenylyl cyclase. Reduced cAMP production leads to reduced activation of cAMP-dependent protein kinase, reduced heart rate, and contraction strength.
Scleroderma, a rare autoimmune disease characterized by abnormal connective tissue growth, can wreak havoc on everything from the skin and heart to lungs, teeth, speech, and movement. The overproduction of collagen causes the skin and organs to harden, leading them to atrophy and possibly fail.
Collagen Mask Side Effects. While dangerous side effects from a collagen mask are rare, some people have reported itching, redness, irritation, and in some rare cases, bruising, from the use of these masks. The more sensitive or thin your skin is, the more likely you are to experience these side effects.