Johann Sebastian Bach born, 21 March, at Eisenach. Youngest child of Johann Ambrosius Bach, town and court musician, and his wife Maria Elisabetha, nÃ©e LÃ¤mmerhirt. Baptised, 23 March.
â¢Parkinson disease 11 (PARK11): Type 11 Parkinson disease is linked to a genetic mutation on chromosome 2q21.2. Parkinson's disease is a chronic, progressive, degenerative brain disorder characterized by tremors, muscle rigidity and slowed movements.
However, only about 10 percent of Parkinson's cases have been linked to a genetic cause. Most cases of Parkinson's are called idiopathic or sporadic, meaning the cause is unknown, and researchers believe onset is due to a combination of genetic and environmental factors. Another gene that plays a role in some people's Parkinson's is LRRK2.