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Lithium has been used for over half a century for the treatment of bipolar disorder as the archetypal mood stabilizer, and has a wealth of empirical evidence supporting its efficacy in this role. Despite this, the specific mechanisms by which lithium exerts its mood-stabilizing effects are not well understood.
Lithium (EskalithÂ®, Eskalith CRÂ®, LithobidÂ®) is a mood-stabilizing medication that is available by prescription only. Lithium products are used to treat bipolar disorder. Specifically, the medicine is approved to treat manic episodes (but not depressive episodes). It is also approved as a maintenance treatment, which is a long-term treatment to help prevent episodes of mania or depression.