Peripheral artery disease (P.A.D.) is a disease in which plaque builds up in the arteries that carry blood to your head, organs, and limbs. Plaque is made up of fat, cholesterol, calcium, fibrous tissue, and other substances in the blood.
Painless swelling may affect both legs and may include the calves or even the thighs. The effect of gravity makes the swelling most noticeable in the lower part of the body. Foot, leg, and ankle swelling is common when the person also: Is overweight.
Causes of Calf Muscle Strain. A pulled calf muscle usually happens suddenly due to injury, but can develop gradually from overuse. A calf muscle strain most commonly affects the larger, more superficial gastrocnemius muscle but can affect the soleus muscle as well.