James Best as Deputy Roscoe P. Coltrane in âThe Dukes of Hazzard,â hugging Flash. James Best, whose prolific career included 83 movies and 600 TV shows but is best remembered for portraying Rosco P. Coltrane, the bumbling sheriff of Hazzard County, died late Monday in Hickory at age 88.
1 Arthritis and osteoarthritis of small joints may affect the thumb joint. It may lead to thumb swelling, pain and restricted thumb movement. Together with thumb, other fingers may also get affected with Arthritis.  Thumb tendonitis and bursitis can also cause inflammation and pain in the thumb.
This phenomenon, known as peripheral neuropathy, can also sometimes cause hand pain. DeQuervain's disease is a swelling and inflammation of the tendon around the thumb, causing pain in the thumb and lower arm. Trauma or injury to any of the structures in the hand is another common cause of hand pain. Medically Reviewed by a Doctor on 3/2/2017.