Johann Sebastian Bach born, 21 March, at Eisenach. Youngest child of Johann Ambrosius Bach, town and court musician, and his wife Maria Elisabetha, nÃ©e LÃ¤mmerhirt. Baptised, 23 March.
â¢Parkinson disease 11 (PARK11): Type 11 Parkinson disease is linked to a genetic mutation on chromosome 2q21.2. Parkinson's disease is a chronic, progressive, degenerative brain disorder characterized by tremors, muscle rigidity and slowed movements.
Parkinson disease-caused by mutations in the SNCA gene. At least 18 mutations in the SNCA gene have been found to cause Parkinson disease, a condition characterized by progressive problems with movement and balance.everal common variations in the SNCA gene have been found to increase the risk of multiple system atrophy, a progressive brain disorder that affects movement and balance and disrupts the function of the autonomic nervous system.