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RH isoimmunization, also referred to as erythroblastosis fetalis is an incompatibility between an infantâs blood and the blood type of the mother.
Rhogam is human antibody to the Rh antigen. If any fetal blood cells escape into the maternal circulation, Rhogam binds to the Rh antigen and makes it âinvisibleâ to the motherâs immune system. One dose at 28 weeks, and another at the time of delivery is enough to prevent the mother becoming sensitized.