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The leaves become bitter and the plants begin to bolt as the stem elongates into a tall bloom stalk. Leaf lettuce varieties take about 40 days from seeding to harvest while head types may take 70 days. This is another reason the head types are more of a challenge. To get more from your garden space, consider interplanting your lettuce with slower maturing crops.
Step 4. Save the seeds of lettuce by letting your lettuce plant go to seed. Allow the seed heads to dry for two to three weeks after flowering. Cut the entire top off of the plant and hang it upside down to dry. Harvest the seeds by gently shaking or rubbing them off of the stalk.