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Mar 13, '09. The headache comes because Morphine produces vasodilation. This is why we give Morphine for chest pain patients. The vasodilation is great to reduce constriction due to angina, but it causes headaches due to the vasodilation.
It's sold under several brand names, including Roxanol, Kadian, and Avinza. Morphine is part of a class of drugs called opiate (narcotic) analgesics, or opioid agonists, which block the transmission of pain signals to the brain by binding to nervous system proteins called opioid receptors.