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Abstract. All eukaryotes have three different RNA polymerases (RNAPs) which transcribe different types of genes. RNA polymerase I transcribes rRNA genes, RNA polymerase II transcribes mRNA, miRNA, snRNA, and snoRNA genes, and RNA polymerase III transcribes tRNA and 5S rRNA genes.Here, we use an in silico approach to identify putative functional differences between these three RNAPs.NA polymerase I transcribes rRNA genes, RNA polymerase II transcribes mRNA, miRNA, snRNA, and snoRNA genes, and RNA polymerase III transcribes tRNA and 5S rRNA genes. Here, we use an in silico approach to identify putative functional differences between these three RNAPs.
In the nucleus of eukaryotes, transcription is carried out by three different RNA polymerases, RNA polymerase I, II and III (Pol I, II and III) (1). Each of them is dedicated to the transcription of distinct sets of genes, but none is able to recognize its target promoters independently.n the nucleus of eukaryotes, transcription is carried out by three different RNA polymerases, RNA polymerase I, II and III (Pol I, II and III) (1). Each of them is dedicated to the transcription of distinct sets of genes, but none is able to recognize its target promoters independently.