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Lithium has been used for over half a century for the treatment of bipolar disorder as the archetypal mood stabilizer, and has a wealth of empirical evidence supporting its efficacy in this role. Despite this, the specific mechanisms by which lithium exerts its mood-stabilizing effects are not well understood.
Purpose. Lithium is commonly used to treat mania and bipolar depression (manic-depression or bipolar disorder). Less commonly, lithium is used to treat certain mood disorders, such as schizoaffective disorder and aggressive behavior and emotional instability in adults and children.urpose. Lithium is commonly used to treat mania and bipolar depression (manic-depression or bipolar disorder). Less commonly, lithium is used to treat certain mood disorders, such as schizoaffective disorder and aggressive behavior and emotional instability in adults and children.