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The cause of itai-itai disease was determined to be cadmium poisoning in the drinking water from the Jinzugawa River basin. The source of cadmium was discovered to be from Mitsui Mining and Smelting Company. Mitsui Mining began to discharge cadmium into the Jinzugawa River in 1910.
In this article, weâll explore the common causes of brittle nails and explore some nutritional cures. Common Causes of Brittle Nails. Low Thyroid (Hypothyroidism) â Brittle nails are sometimes a sign of a more serious illness. One of the most common causes of brittle and breaking nails is low thyroid, also called hypothyroidism. In hypothyroidism, your body does not produce enough of the thyroid hormone, leading to symptoms such as weakness, fatigue, dry skin, brittle nails, depression, constipation, memory trouble, and irregular periods.