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RH isoimmunization, also referred to as erythroblastosis fetalis is an incompatibility between an infantâs blood and the blood type of the mother.
Rh type is needed during pregnancy to assess the risk of hemolytic disease of the newborn (HDN). In this condition, fetal red blood cells are destroyed by antibodies that are formed in the pregnant woman and that cross the placenta and into the fetal blood.