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RH isoimmunization, also referred to as erythroblastosis fetalis is an incompatibility between an infantâs blood and the blood type of the mother.
The Rh blood group system (including the Rh factor) is one of thirty-five current human blood group systems. It is the second most important blood group system, after ABO, and it consists of 50 defined blood-group antigens, among which the five antigens D, C, c, E, and e are the most important. The commonly used terms Rh factor, Rh positive and Rh negative refer to the D antigen only.