ONJ has not been linked with the routine use of bisphosphonates taken by mouth as treatment for osteoporosis. Thus, people should still use oral bisphosphonates as prescribed. However, when possible, any necessary oral surgery should be done before use of bisphosphonates is begun.
Remove nozzle tips and screens, and clean them using a cleaning solution. Use a brush with plastic bristles to clean the nozzle tips. Rinse the cleaning solution off all parts with clean water. Many nozzle manufacturers have brushes designed specifically for cleaning out nozzles.
Remove any mucus in the nasal passages by blowing your nose. Shake the bottle of nose spray and remove the cap. Tilt your head down (look towards the floor). Hold the spray bottle in the palm of one hand and place the tip of the nozzle in the opposite nostril.