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Causes of strokes include ischemia (loss of blood supply) or hemorrhage (bleeding) in the brain occurs. People at risk for stroke include those who have high blood pressure, high cholesterol, diabetes, and those who smoke. People with heart rhythm disturbances, especially atrial fibrillation are also at risk.
A Scripps Health answered. A stroke occurs when blood flow to the brain is disrupted, either by a blood clot blocking a blood vessel or when a blood vessel tears. Deprived of the oxygen carried by blood, brain cells begin to die, causing brain damage. If the brain is without oxygen for too long, a stroke can be fatal.