Inhibition of Adenylate Cyclase: The muscarinic receptor, through interaction with an inhibitory GTP-binding protein, acts to inhibit adenylyl cyclase. Reduced cAMP production leads to reduced activation of cAMP-dependent protein kinase, reduced heart rate, and contraction strength.
In someone suffering with scleroderma, collagen (a protein manufactured by the connective tissues of the body) is produced in excess. This over-production of collagen can be likened to the process of scarring, which is the way the body heals a wound. For persons with scleroderma, the scarring gets out of hand.
Collagen is a protein that works like glue to bind cells together. Itâs the most abundant of fibers in our connective tissue, which gives our bodies form and support. Collagen is found in the connective tissue of our skin, teeth, bones, organs, and cartilage.Collagen keeps our skin firm and resilient, protecting it from wrinkling. The role of vitamin C in the production of collagen is to interact with amino acids within collagen cells.It adds hydrogen and oxygen to those amino acids, so that they may do their part in collagen production. If you donât get the proper amount of vitamin C, collagen production will slow.ollagen keeps our skin firm and resilient, protecting it from wrinkling. The role of vitamin C in the production of collagen is to interact with amino acids within collagen cells. It adds hydrogen and oxygen to those amino acids, so that they may do their part in collagen production.