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The research shows that when the rashes tend to disappear, the skin starts to peel off. Therefore, scarlet fever does not cause peeling of skin but causes the appearance of rashes. Tinea manuum; It is a fungal infection that affects the delicate skin of the hands and fingers. It later results in scaling and flaking of the skin.
Visage/Stockbyte/Getty Images. Psoriasis is an infection that often causes peeling of the hands, although it can occur on other parts of the body as well. The main symptom of psoriasis, other than peeling, is the presence of a scaly rash on the skin.