Peripheral artery disease (P.A.D.) is a disease in which plaque builds up in the arteries that carry blood to your head, organs, and limbs. Plaque is made up of fat, cholesterol, calcium, fibrous tissue, and other substances in the blood.
Painless swelling may affect both legs and may include the calves or even the thighs. The effect of gravity makes the swelling most noticeable in the lower part of the body. Foot, leg, and ankle swelling is common when the person also: Is overweight.
But there are other reasons your calf may suddenly cause you pain. Calf Muscle Cramp -A far less severe, but often painful, cause of calf pain is the muscle cramp or spasm. This involuntary contraction of a muscle is short-lived, but in may be so strong that it causes a bruise.