Peripheral artery disease (P.A.D.) is a disease in which plaque builds up in the arteries that carry blood to your head, organs, and limbs. Plaque is made up of fat, cholesterol, calcium, fibrous tissue, and other substances in the blood.
Painless swelling may affect both legs and may include the calves or even the thighs. The effect of gravity makes the swelling most noticeable in the lower part of the body. Foot, leg, and ankle swelling is common when the person also: Is overweight.
A Bakers Cyst is a common cause of upper calf pain caused by inflammation of the popliteal bursa (fluid filled sac) that sits behind the knee joint. It can cause calf muscle pain, particularly if the cyst bursts resulting in the fluid tracking down the leg into the triceps surae.