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Meconium aspiration syndrome (MAS) also known as neonatal aspiration of meconium is a medical condition affecting newborn infants.econium passage into the amniotic fluid occurs in about 5â20 percent of all births and is more common in overdue births. Of the cases where meconium is found in the amniotic fluid, meconium aspiration syndrome develops less than 5 percent of the time.
Meconium aspiration syndrome is respiratory distress in a newborn who has breathed (aspirated) meconium into the lungs before or around the time of birth.Fetuses may pass stools (meconium) in response to stress, such as a lack of oxygen.econium aspiration syndrome is often most severe in postmature newborns because they have a smaller volume of amniotic fluid so the meconium is concentrated in a smaller amount of amniotic fluid (see Postmaturity).