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Lithium has been used for over half a century for the treatment of bipolar disorder as the archetypal mood stabilizer, and has a wealth of empirical evidence supporting its efficacy in this role. Despite this, the specific mechanisms by which lithium exerts its mood-stabilizing effects are not well understood.
It helps make mania less severe and more rare. And it may also help relieve or prevent bipolar depression in some people. Studies show that lithium can lower the risk of suicide among people with bipolar disorder. It also helps prevent future manic episodes. Doctors may prescribe it for long periods of time as maintenance therapy. What It Is: Lithium is a drug that acts on the brain and spinal cord.