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A pulse oximeter probe applied to a person's finger. A pulse oximeter is a medical device that indirectly monitors the oxygen saturation of a patient's blood (as opposed to measuring oxygen saturation directly through a blood sample) and changes in blood volume in the skin, producing a photoplethysmogram.ulse oximetry is a non-invasive method for monitoring a person's O 2 saturation.
What does a pulse oximeter measure? 1  The oxygen saturation of haemoglobin in arterial blood-which is a measure of the average amount of oxygen bound to each haemoglobin molecule. 2  The percentage saturation is given as a digital readout. 3  The pulse rate-in beats per minute, averaged over 5 to 20 seconds. The oxygen saturation of haemoglobin in arterial blood-which is a measure of the average amount of oxygen bound to each haemoglobin molecule. 2  The percentage saturation is given as a digital readout. 3  The pulse rate-in beats per minute, averaged over 5 to 20 seconds.