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Leukotriene modifier. Montelukast (Singulair) can ease both allergy and asthma symptoms. Called a leukotriene modifier, this daily pill helps control immune system chemicals released during an allergic reaction. In rare cases, montelukast has been linked to psychological reactions, including suicidal thinking.
Singulair is available as oral tablets, oral granules, or chewable tablets. Side effects of Singulair can include skin rash, mood changes, tremors, headache, stomach pain, heartburn, upset stomach, nausea, diarrhea, tooth pain, tiredness, fever, stuffy nose, sore throat, cough, and hoarseness.Singulair may interact with phenobarbital or rifampin.ess serious side effects may include: 1  headache; 2  stomach pain, heartburn, upset stomach, nausea, diarrhea; 3  tooth pain; 4  tired feeling; 5  fever, stuffy nose, sore throat, cough, hoarseness; or.