Appendicitis occurs when the appendix becomes blocked, often by stool, a foreign body, or cancer. Blockage may also occur from infection, since the appendix swells in response to any infection in the body.
A familial generation is a group of living beings constituting a single step in the line of descent from an ancestor. In developed nations the average familial generation length is in the high 20s and has even reached 30 years in some nations.
There is no specific definition. Many people use 20 years as a general estimate, but it varies. Some use 25 years and some are beginning to use 33 years. A father can be 60 years older than his son and that would make that generation 60 years.