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Pituitary dependent hypercortisolism, more commonly known as Cushing's disease, is caused by a pituitary tumor (non-cancerous) that triggers excessive levels of the stress hormone cortisol.
A 12-Month Phase 3 Study of Pasireotide in Cushing's Disease Cushing's disease is a rare disorder of chronic hypercortisolism due to a corticotropin-secreting pituitary adenoma. This study assessed pasireotide, a somatostatin-receptorâbinding analogue, at two dose levels for the treatment of Cushing's disease.