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The initial symptoms of liver failure are often ones that can be due to any number or conditions. Because of this, liver failure may be initially difficult to diagnose. Early symptoms include: 1  Nausea. 2  Loss of appetite. 3  Fatigue.he initial symptoms of liver failure are often ones that can be due to any number or conditions. Because of this, liver failure may be initially difficult to diagnose. Early symptoms include: 1  Nausea. 2  Loss of appetite. 3  Fatigue.
Either the liver or the brain can be harmed first, with signs as early as 4 years, or as late as 70 years of age. 1  Symptoms of liver disease include: 2  Jaundice, which is when the skin or the white part of the eye turns yellow. 3  Fatigue. 4  Loss of appetite. 5  Swelling in the abdomen. 6  Easy bruising.