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Many medicines can cause acute kidney injury (acute renal failure), such as: Antibiotics. These include aminoglycosides, cephalosporins, amphotericin B, bacitracin, and vancomycin. Some blood pressure medicines. One example is ACE inhibitors, such as lisinopril and ramipril. Another is angiotensin receptor blockers.
The list of individual drugs that cause kidney damage is so long that it's hard to decide on the top ten. So I've chosen to list them by type of drug: antibiotic, analgesic, etc. Top ten drugs that cause kidney damage: 1. Antibiotics, including ciprofloxacin, methicillin, vancomycin, sulfonamides.