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A high white blood cell count may be caused by a wide range of conditions, which include normal physiological responses to stress, allergic reactions, infection and serious conditions such as cancer. Treatment usually depends on the cause or disease.
Bacterial and viral infections are the most common causes of a high white blood cell count. Fungal or parasitic infections can also increase the number of white blood cells in the blood. The increase in WBCs due to infection is caused by a normal immune system response that stimulates the bone marrow to release stored white blood cells.