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Pituitary dependent hypercortisolism, more commonly known as Cushing's disease, is caused by a pituitary tumor (non-cancerous) that triggers excessive levels of the stress hormone cortisol.
Pituitary tumors are growths which impair the normal function of your pituitary gland. The pituitary gland is often considered the master gland.. It regulates most of the body's hormonal balance. One of the hormones created by the pituitary gland is growth hormone.If your pituitary gland produces too much adrenocorticotropic hormone (ACTH), this is called Cushing's disease. The symptoms of Cushing's disease include: 1  Fat accumulations in the face, above the clavicles, and the back of the neck. 2  Skin thinning.he pituitary gland is often considered the master gland.. It regulates most of the body's hormonal balance. One of the hormones created by the pituitary gland is growth hormone. If your pituitary gland produces too much adrenocorticotropic hormone (ACTH), this is called Cushing's disease.