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TRH stimulation test. Prior to the availability of sensitive TSH assays, thyrotropin releasing hormone (TRH) stimulation tests were relied upon for confirming and assessing the degree of suppression in suspected hyperthyroidism. Typically, this stimulation test involves determining basal TSH levels and levels 15 to 30 minutes after an intravenous bolus of TRH.
thyrotropin. a hormone secreted by the anterior lobe of the pituitary gland that has an affinity for and specifically stimulates the thyroid gland. Called also thyroid-stimulating hormone (TSH).hyrotropin releasing hormone (TRH). a tripeptide produced in the hypothalamus and released into the hypothalamohypophyseal portal circulation to reach the adenohypophysis where it triggers the release of thyroid-stimulating hormone.