SAMe (s-adenosyl-L-methionine). Several studies suggest SAMe can help reduce OA pain. In one study, SAMe relieved pain as well as NSAIDs. In another study of people with knee OA, SAMe worked as well as Celebrex in lessening pain and improving joint function, although it took longer to feel the benefits.
Heartburn is felt when stomach acid flows back up into the esophagus (food pipe or gullet), down which food moves from the mouth to the stomach. At least 15 million Americans experience heartburn - the symptom of acid reflux - every day, according to estimates from the American College of Gastroenterology.
Heartburn is most commonly caused when the esophageal sphincter relaxes more often than it is supposed to, allowing stomach acid to flow up into the esophagus. That causes a burning sensation behind the breastbone or acidic fluid surging up into the mouth.