Pulmonary arterial hypertension is a rare but severe disease with an estimated five-year survival rate of only 57% after diagnosis, according to the Registry to Evaluate Early And Long-term PAH disease management (REVEAL), which registers data from patients in the United States.
Concentration of elements in the ocean relative to the total concentration in the bulk silicate Earth (BSE). Of all the elements, only Cl and Br have a significant fraction in the ocean (see inset), indicating the extreme hydrophilic character for the heavier halogens.
Bromine is rarer than about three-quarters of elements in the Earth 's crust. The high solubility of bromide ions has caused its accumulation in the oceans, and commercially the element is easily extracted from brine pools, mostly in the United States, Israel and China.romine is rarer than about three-quarters of elements in the Earth 's crust. The high solubility of bromide ions has caused its accumulation in the oceans, and commercially the element is easily extracted from brine pools, mostly in the United States, Israel and China.