Hoffman practices method acting, and is widely considered a pain in the ass to work with. He is renowned for his big ego and in-depth character research, and for demands of directors, suggestions for co-stars and scriptwriters, endless ideas for plot revisions, and numerous fights with studio executives.
Heart disease remains the leading cause of death in the U.S., accounting for almost 1 in every 4 deaths, and affecting significantly more men than women. 1  Annually there are around 2,626,418 deaths registered in the U.S. with the leading top 10 causes accounting for nearly 75 percent of all deaths.
If the higher estimates are used, the deaths due to iatrogenic causes would range from 230,000 to 284,000. In any case, 225,000 deaths per year constitutes the third leading cause of death in the United States, after deaths from heart disease and cancer. Even if these figures are overestimated, there is a wide margin between these numbers of deaths and the next leading cause of death (cerebrovascular disease).