Appendicitis occurs when the appendix becomes blocked, often by stool, a foreign body, or cancer. Blockage may also occur from infection, since the appendix swells in response to any infection in the body.
A familial generation is a group of living beings constituting a single step in the line of descent from an ancestor. In developed nations the average familial generation length is in the high 20s and has even reached 30 years in some nations.
The length of a generation is not an arbitrary period of time that occurs within the life span of an individual or group of people. Joshua's age at the time of death, 110 years (including 9 months gestation), was the length of the generation he represented. Some of his generation died before him and some after him.