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The initial symptoms of liver failure are often ones that can be due to any number or conditions. Because of this, liver failure may be initially difficult to diagnose. Early symptoms include: 1  Nausea. 2  Loss of appetite. 3  Fatigue.he initial symptoms of liver failure are often ones that can be due to any number or conditions. Because of this, liver failure may be initially difficult to diagnose. Early symptoms include: 1  Nausea. 2  Loss of appetite. 3  Fatigue.
Men and women experience similar signs and symptoms of liver disease. Some men and women exhibiting signs of liver disease may have bloody, tar-colored or pale stool color and a tendency to bruise easily, explains Mayo Clinic. Persistent symptoms of liver disease should be reported to a physician.