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Freebase(0.00 / 0 votes)Rate this definition: Hydronephrosis â literally water inside the kidney â refers to distension and dilation of the renal pelvis and calyces, usually caused by obstruction of the free flow of urine from the kidney. Untreated, it leads to progressive atrophy of the kidney.
Hydronephrosis is the swelling of a kidney due to a build-up of urine. It happens when urine cannot drain out from the kidney to the bladder from a blockage or obstruction. Hydronephrosis can occur in one or both kidneys. The main function of the urinary tract is to remove wastes and fluid from the body.