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Alka-Seltzer Plus Cold and Cough is a combination medicine that treats cold and flu symptoms. Aspirin relieves pain and reduces fever. Chlorpheniramine is an antihistamine that treats runny nose and watery eyes. Dextromethorphan is a cough suppressant. Phenylephrine is a decongestant that clears your sinuses.
Who Invented Alka Seltzer. The combination of baking soda and aspirin had been known for several years to be a beneficial remedy for several ailments. The only problem was that they were taken individually and Miles Laboratories wanted to be able to combine them in a way that would make it easy for people to take.