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Even if the substance is present in slightest amount in the bloodstream the test will detect its presence and indicate accordingly. Nicotine stays in your blood for maximum 3 days after the last nicotine product you consume.
Best Answer: How long does The Nicotine Stay in your System or Blood stream? Officially it is 48 hours but I say 72-96 hours. That's the thing with nicotine it acts fast but also leaves the body quickly.