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A cortisol test measures the level of the hormone cortisol in a 24-hour sample of urine. The cortisol level may show problems with the adrenal glands or the pituitary gland. Cortisol is made by the adrenal glands.
Cortisol is a steroid hormone produced by the zona fasciculata, the middle of three layers of the adrenal cortex located in the kidneys, and regulated by the pituitary gland in the brain. This hormone is important for the immune system, regulating blood pressure, the cardiovascular system, metabolism, and more.ow Cortisol Symptoms, Causes, and Treatments. March 16, 2014 by C. Paris. Cortisol, or hydrocortisone, is a steroid hormone (glucocorticoid) that is vital to the endocrine system released by the adrenal cortex to combat stress. Maintaining healthy levels of cortisol is essential to keeping in good health.