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The initial symptoms of liver failure are often ones that can be due to any number or conditions. Because of this, liver failure may be initially difficult to diagnose. Early symptoms include: 1  Nausea. 2  Loss of appetite. 3  Fatigue.he initial symptoms of liver failure are often ones that can be due to any number or conditions. Because of this, liver failure may be initially difficult to diagnose. Early symptoms include: 1  Nausea. 2  Loss of appetite. 3  Fatigue.
1 The early symptoms of liver damage include fatigue, weakness, lack of appetite, loss of energy, weight loss and nausea. 2  A damaged liver cannot remove bilirubin from the blood. 3  The skin and the white part of the eyes become yellow due to its presence in the blood.