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The initial symptoms of liver failure are often ones that can be due to any number or conditions. Because of this, liver failure may be initially difficult to diagnose. Early symptoms include: 1  Nausea. 2  Loss of appetite. 3  Fatigue.he initial symptoms of liver failure are often ones that can be due to any number or conditions. Because of this, liver failure may be initially difficult to diagnose. Early symptoms include: 1  Nausea. 2  Loss of appetite. 3  Fatigue.
Some common liver disease symptoms include the following, each of which are described briefly below: 1  Jaundice. A yellowing of the skin and eyes. 2  Cholestasis. 3  Liver enlargement.  Portal 1  hypertension. Esophageal varices.  Ascites. A fluid buildup in the abdominal 1  cavity. Liver encephalopathy.  Liver failure.