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Pituitary dependent hypercortisolism, more commonly known as Cushing's disease, is caused by a pituitary tumor (non-cancerous) that triggers excessive levels of the stress hormone cortisol.
Cushing's syndrome Cushing's syndrome - a disease where too much cortisol is being made is named after Harvey Cushing, a famous neurosurgeon at Johns Hopkins Hospital who first described it. Patients who have Cushing's syndrome have too much cortisol Cortisol - a glucocorticoid that controls glucose production and suppresses the immune system or steroid in their blood.