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Hand cramps are a result of hand muscles and nerve condition. A  common cause of cramping is dehydration, heat exhaustion, fatigue,  and injury or trauma of nerves. This is â¦also common in people with  diabetes and to any condition that affects the nerves outside the  brain and spinal cord. David BÃ¤ckman.
Muscle Cramping (Hemodialysis) Muscle cramping of the hands, feet, and legs is fairly common on hemodialysis. The cause of muscle cramping is unknown. However, three conditions that seem to increase cramping are: 1) hypotension; 2) the patient being below dry weight; and 3) use of low sodium dialysis solution. Muscle cramps are more commonly associated with low blood pressure.