1 A person may or may not have any symptoms previously, but all of the sudden a plaque ruptures, triggering a chain of events and a sudden heart attack.  The other is a more gradual progression of coronary disease. In these patients, an artery is getting narrower over time.
Knee pain at night causes. Common causes of knee pain at night include sprains and strains, anterior knee pain, menisci or cartilage damage, osteoarthritis tendonitis, bursitis, torn ligaments or tendons, bleeding into the joint, Osgood Shatlerâs disease, gout, septic arthritis, overuse, and obesity.
'It is not clear why shingles pain gets worse at night, but it could be to do with levels of neurotransmitters, chemicals that transmit signals from a neuron to target cells, and hormones involved in pain perception, rising at night,' says John Oxford, a professor of virology at Queen Mary College University of London.