Actinic keratoses that develop on the lips are referred to as actinic cheilitis. The clinical appearance of an actinic keratosis is that of a small (several millimeters), red scaly papule or plaque, with induration and thickening of the epidermis.
1 Location: Ideally, the probe should be in close proximity to the forward or reverse primer, but should not overlap with a primer-binding site on the same strand. 2  Probes can be designed to bind to either strand of the target. 3  Melting temperature (Tm): Preferably, probes should have a Tm 6â8Â°C higher than the primers.
Selected probes must be sufficiently small in caliber to fit inside the endoscopic channel and must be sufficiently long to traverse the shaft of the endoscope. The endoscopist should specify the settings on the electro-cautery machine when using the BICAP or Gold Probeâ¢. The water pump is generally set to maximum strength. The nurse should test the pump before inserting it down the endoscopic channel.