Phosphorylation of signal transduction molecules is a major activating event that leads to dramatic changes in tumor growth. Some TKs, such as epidermal growth factor receptor (EGFR)-TK, can autophosphorylate when activated, as well as phosphorylating other signaling molecules [2].
Risk indexes Definition: Categories of risk used to calculate fundamental beta, including (1) market variability, (2) earnings variability, (3) low valuation, (4) immaturity and smallness, (5) growth orientation, and (6) financial risk.
Type of risk: Value at Risk measures the likelihood of losses to an asset or portfolio due to market risk. Implicit in this definition is the narrow definition of risk, at least in conventional VaR models. First, risk is almost always considered to be a negative in VaR.