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VERY DIFFERENT: Parkinson's is disease of misfolded protein usually occurring in older males, associated with tremor, stiffness, loss of balance, etc. Multiple sclerosis is an autoimmune mediated disorder of people in their 20's and 30's, occas in childhood, and typically a pattern of ...Read more.
What Are the Motor Symptoms of Parkinson's Disease? People are usually more familiar with the motor symptoms of PD, as these are the signs of the disease that are noticeable from the outside. These symptoms, known as the cardinal symptoms of PD, include: 1  Bradykinesia (slowness of movement) -- slowing down and loss of spontaneous and voluntary movement. 2  Rigidity -- unusual stiffness in a limb or other body part.