Actinic keratoses that develop on the lips are referred to as actinic cheilitis. The clinical appearance of an actinic keratosis is that of a small (several millimeters), red scaly papule or plaque, with induration and thickening of the epidermis.
1 Location: Ideally, the probe should be in close proximity to the forward or reverse primer, but should not overlap with a primer-binding site on the same strand. 2  Probes can be designed to bind to either strand of the target. 3  Melting temperature (Tm): Preferably, probes should have a Tm 6â8Â°C higher than the primers.
If your chamber is very dirty your bolt may have trouble going all the way forward. The forward assist lets you push it to full lockup. It's debatable whether or not it's a good idea to chamber a round that won't go in on its own but I'd rather have it than not. Another use is for silent loading, where if you ride your charging handle home instead of letting it snap forward you can press the forward assist to close the bolt completely.