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Long-term treatment with ibuprofen at a dose of 1200 mg/day does not increase the risk of renal impairment in elderly people (Griffin et al, 2000). Ibuprofen is associated with a low risk of renal toxicity in overdose (Jenkinson et al, 1988; Volans and Fitzpatrick, 1999).
Â· just now. Report Abuse. the maximum recommended dose of ibuprofen is 2400 mg per day. Taking 3000 mg will cause stomach upset and can cause stomach bleeding, but shouldn't cause long term lasting damage to organs, unless consumed on a continuous basis. just now. Report Abuse. the maximum recommended dose of ibuprofen is 2400 mg per day. Taking 3000 mg will cause stomach upset and can cause stomach bleeding, but shouldn't cause long term lasting damage to organs, unless consumed on a continuous basis.