The creditor and issuer of these cards is U.S. Bank National Association, pursuant to a license from Visa U.S.A. Inc. Â© 2016 H-D or its affiliates. HARLEY-DAVIDSON, HARLEY, H-D, and the Bar and Shield Logo are among the trademarks of H-D U.S.A., LLC. Third-party trademarks are the property of their respective owners.
Inhibitors are a serious medical problem that can occur when a person with hemophilia has an immune response to treatment with clotting factor concentrates. The immune system defends the body from harmful germs and viruses.
a molecule that prevents an enzyme from catalysing a reaction. Such inhibitors can compete with the normal substrate (see COMPETITIVE INHIBITION or can block the active site, preventing entry of the substrate (see NONCOMPETITIVE INHIBITION). Inhibition may be reversible or irreversible. Enzyme inhibitors often form part of a FEEDBACK MECHANISM to regulate a biochemical pathway.