Many congenital brain defects cause minor neurological impairment. People with these types of congenital brain defects can grow to function independently. Other defects are so severe that they are fatal before or shortly after birth. Some cause significant disabilities.
I am looking into this for a friend as well. The pancreas deals with digestive juices and insulin. Have a look at your medications to see if they may have gastrointestinal effects. I can tell you that Tramadol does affect the production of enzymes in the intestine.
Januvia, Janumet Linked to Risk of Pancreatic Injury. Concerns about the safety of Januvia and Janumet arose in February 2013 after a study was published by the journal JAMA Internal Medicine. The study revealed that patients taking Januvia and Janumet or similar medications were twice as likely to develop acute pancreatitis.