Actinic keratoses that develop on the lips are referred to as actinic cheilitis. The clinical appearance of an actinic keratosis is that of a small (several millimeters), red scaly papule or plaque, with induration and thickening of the epidermis.
1 Location: Ideally, the probe should be in close proximity to the forward or reverse primer, but should not overlap with a primer-binding site on the same strand. 2  Probes can be designed to bind to either strand of the target. 3  Melting temperature (Tm): Preferably, probes should have a Tm 6â8Â°C higher than the primers.
Falling deep into its gravity well will accelerate Juno to a velocity of about 160,000 miles per hour relative to the planet, before it can swing by, drop speed, and get into its mission orbit. In 2018 though, a new NASA mission â Solar Probe Plus â will be launched. Designed to come as close as 8.5 solar radii to the Sun (thatâs about about 5.9 million kilometers or 3.7 million miles), it will hit orbital velocities as high as 200 kilometers a second (450,000 miles an hour).