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VERY DIFFERENT: Parkinson's is disease of misfolded protein usually occurring in older males, associated with tremor, stiffness, loss of balance, etc. Multiple sclerosis is an autoimmune mediated disorder of people in their 20's and 30's, occas in childhood, and typically a pattern of ...Read more.
These are common symptoms of Parkinson disease: 1  Tremors that affect the face and jaw, legs, arms, and hands. 2  Slow, stiff walking. 3  Trouble maintaining balance.  Problems with 1  coordination. A stiff feeling in arms, legs, and torso area.  Changes in handwriting.