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VERY DIFFERENT: Parkinson's is disease of misfolded protein usually occurring in older males, associated with tremor, stiffness, loss of balance, etc. Multiple sclerosis is an autoimmune mediated disorder of people in their 20's and 30's, occas in childhood, and typically a pattern of ...Read more.
The most common symptoms of Parkinsonâs disease include: (5) 1  Trembling: This is one of many changes in movement (motor) functions and usually affects the arms, jaw, legs and face. 2  Rigidity: Most patients experience stiffness of the bodyâs core (trunk area) as well as in their arms and legs.