A regulatory framework Although common in other process manufacturing industries (e.g., food and chemicals), continuous processing is at a nascent stage in the pharmaceutical industry, where batch manufacturing is the prevailing mode.
When the motor neurons in the brainstem are affected (bulbar ALS), the muscles used in speech and swallowing are impaired. ALS only affects muscles that are moved voluntarily (such as those in the mouth or arm) and does not impact those muscles involved in involuntary movements, such as digestion.
1 When ALS affects the muscles involved in eating: i.e. chewing, moving food in your mouth and swallowing. 2  When eating leads to fatigue and one has difficulty eating enough to sufficiently nourish your body.  When noticeable weight loss, malnutrition and dehydration are present.