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L-arginine has unpredictable effects on insulin and cholesterol-lowering agents. L-arginine may increase the effects of isosorbide mononitrate and other nitric oxide donors, such as glyceryl trinitrate and sodium nitroprusside. Side Effects. L-arginine has few reported adverse reactions. Nausea and diarrhea have been reported infrequently.
Metformin long term side effects. Common Questions and Answers about Metformin long term side effects. glucophage. Yes, one nasty side effect of Metformin is nausea. He should have been aware of this from reading the pharmaceutical paperwork that accompanied the Metformin bottle, or by his Pharmacist.