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VERY DIFFERENT: Parkinson's is disease of misfolded protein usually occurring in older males, associated with tremor, stiffness, loss of balance, etc. Multiple sclerosis is an autoimmune mediated disorder of people in their 20's and 30's, occas in childhood, and typically a pattern of ...Read more.
Parkinson's disease symptoms and signs may vary from person to person. Early signs may be mild and may go unnoticed. Symptoms often begin on one side of your body and usually remain worse on that side, even after symptoms begin to affect both sides.Parkinson's signs and symptoms may include: 1  Tremor. 2  A tremor, or shaking, usually begins in a limb, often your hand or fingers.arkinson's signs and symptoms may include: 1  Tremor. 2  Slowed movement (bradykinesia). 3  Rigid muscles. 4  Impaired posture and balance. 5  Loss of automatic movements. 6  Speech changes. 7  Writing changes.