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Causes of Human Skin Hyperpigmentation. The color of human skin is due primarily to the production of melanin by specialized cells in the skin called melanocytes. Melanin produced by these cells both absorbs and scatters UV radiation and thus protects skin from the damaging and mutagenic effects of the solar radiation.
Melanocyte-stimulating hormone levels are also raised during pregnancy and in women using birth control pills, which can cause hyperpigmentation of the skin. Cushingâs syndrome, due to an excess production of adrenocorticotropic hormone, can also lead to hyperpigmentation.rint | Email article to a friend | Last updated: March 31, 2015. Melanocyte-stimulating hormone describes a group of hormones produced by the pituitary gland, hypothalamus and skin cells. It is important for protecting the skin from UV rays, development of pigmentation and control of appetite.