Today's true sports drinks are still the classic Gatorade -- packed with the electrolytes potassium, magnesium, calcium, and sodium to provide energy during intense workouts -- as well as competitors such as Cytomax, Allsport, and Accelerade.
Certain medications can also cause Charley horse as a result of their side effects. Drugs such as statins or medicines prescribed for lowering cholesterol, blood pressure, diuretics, asthma medicines like terbutaline and salbutamol, morphine and lithium can trigger muscle spasms.
Some of the common causes of Charlieâs Horses in legs are: 1  Mineral deficiency: Low levels of mineral such as potassium and calcium may lead to cramping. Low levels of minerals causes the muscle to contract but prevents it from relaxing. 2  Low levels of body fluids while doing strenuous exercise may lead to Charlie Horses.