22q11.2 deletion syndrome is caused by the deletion of a small section of chromosome 22. It results in a cleft palate, heart defects, autoimmune disorders, and more. The symptoms vary wildly and can be accompanied by learning disabilities and mental illness. Cystic fibrosis is caused by a point deletion.
The melody of Happy Birthday to You comes from the song  Good Morning to All , which has been attributed to American siblings Patty Hill and Mildred J. Hill in 1893, although the claim that the sisters composed the tune is disputed.
Celebrate your birthday all year long with these cheerful Happy Birthday Mugs by Konitz. The big, brightly-colored balloons both outside and inside each mug, along with the bold birthday greeting, will put a smile to your face all 365 days of the year.