Actinic keratoses that develop on the lips are referred to as actinic cheilitis. The clinical appearance of an actinic keratosis is that of a small (several millimeters), red scaly papule or plaque, with induration and thickening of the epidermis.
1 Location: Ideally, the probe should be in close proximity to the forward or reverse primer, but should not overlap with a primer-binding site on the same strand. 2  Probes can be designed to bind to either strand of the target. 3  Melting temperature (Tm): Preferably, probes should have a Tm 6â8Â°C higher than the primers.
A space probe is a spacecraft which travels into space with no people in it, usually in order to study the planets and send information about them back to earth. Its rings were discovered by telescope from Earth, but space probes later found that spectacular rings surround some other planets. The Pioneer probes have on board ultra-violet instruments which are measuring light that we can't measure on the earth.