Many congenital brain defects cause minor neurological impairment. People with these types of congenital brain defects can grow to function independently. Other defects are so severe that they are fatal before or shortly after birth. Some cause significant disabilities.
I am looking into this for a friend as well. The pancreas deals with digestive juices and insulin. Have a look at your medications to see if they may have gastrointestinal effects. I can tell you that Tramadol does affect the production of enzymes in the intestine.
Other Drugs. While other cardiovascular drugs can slow the heart rate -- such as clonidine (Catapres) and sotalol (Betapace) -- some drugs were specifically designed to exert their effects via specialized actions on specific parts of the heart, including its intricate electrical conduction system. This system controls and coordinates the heart rate.