In contemporary standard English, these are the second-person pronouns: 1  you (singular and plural personal pronoun). 2  yours (singular and plural possessive pronoun). 3  yourself and yourselves (singular and plural reflexive / intensive pronouns).
A Cochrane review came to the result that in women starting hormone replacement therapy less than 10 years after menopause have a lower mortality and lower rate of coronary heart disease compared to placebo or no treatment, without any strong evidence of an effect on the risk of stroke.
But up to now, larger studies have not demonstrated that hormone replacement is beneficial to sleep despite many anecdotal stories of miraculous improvement. Estrogen is not sedating, but the brain experiences a withdrawal-like syndrome in menopause and the result can be surging levels of noradrenalin.