Phosphorylation of signal transduction molecules is a major activating event that leads to dramatic changes in tumor growth. Some TKs, such as epidermal growth factor receptor (EGFR)-TK, can autophosphorylate when activated, as well as phosphorylating other signaling molecules [2].
Risk indexes Definition: Categories of risk used to calculate fundamental beta, including (1) market variability, (2) earnings variability, (3) low valuation, (4) immaturity and smallness, (5) growth orientation, and (6) financial risk.
We refer to this phenomenon as the âbond risk premiumâ (the bond risk. premium is also sometimes called the term premium or the maturity premium). The bond risk premium is closely related to the more familiar concept of the. equity risk premium. Equities are a relatively risky asset class, with high volatility.