Actinic keratoses that develop on the lips are referred to as actinic cheilitis. The clinical appearance of an actinic keratosis is that of a small (several millimeters), red scaly papule or plaque, with induration and thickening of the epidermis.
1 Location: Ideally, the probe should be in close proximity to the forward or reverse primer, but should not overlap with a primer-binding site on the same strand. 2  Probes can be designed to bind to either strand of the target. 3  Melting temperature (Tm): Preferably, probes should have a Tm 6â8Â°C higher than the primers.
Diode is an unipolar device, i.e. it has a p-type side and a n-type side, and their connection matters. Forward Bias: When the p-type side of the diode is connected to a higher potential than the n-type side, the diode is said to be forward biased, because it enhances the capability of the diode to conduct forward current.