The pathogenesis of HIE in the newborn period involves the same key players that are also present in adults, namely energy crisis from hypoxia-ischemia, lactic acidosis, excitotoxicity, and free radicals, but there are some important modifiers, which account for different patterns of pathology in newborn babies.
Chordates (phylum Chordata) are a group of animals that includes all the vertebrates (subphylum Vertebrata), as well as two subphylum of invertebrates, the Urochordata (tunicates) and the Cephalochordata (lancelets).lso, the relationships of some chordate groups are not very well understood. 1  Phylum Chordata. 2  Subphylum Urochordata (Tunicates). 3  Subphylum Cephalochordata (Lancelets). 4  Class Myxini or Hyperotreti (hagfish). 5  Subphylum Vertebrata (Vertebrates-animals with backbones). 6  Class Conodonta (Conodonts).
The tunicates (subphylum Urochordata) are a group of about 1250 species of marine animals. Most of them are sessile as adults, with only the larvae having a notochord and nerve cord. As adults, they exhibit neither a major body cavity nor visible signs of segmentation. Most species occur in shallow waters, but some are found at great depths.