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nodule - (mineralogy) a small rounded lump of mineral substance (usually harder than the surrounding rock or sediment) mineralogy - the branch of geology that studies minerals: their structure and properties and the ways of distinguishing them.
A macule is a small (up to 1cm in diameter), circumscribed, flat, and thus nonpalpable change in the pigmentation of the skin. When I say flat, I mean that a macule is neither raised from the skin, like a mole, nor depressed into the skin like stretch marks. That's why it's nonpalpable.