what causes liver and spleen swelling 1 One of the most likely causes of an enlarged spleen is an infection, since swelling in the spleen signifies an increase in white blood cells that are trying to attack something threatening. 2  Leishmaniasis, a type of parasitic disease found in parts of the tropics, subtropics and southern Europe, can lead to an enlarged spleen. more information...
Do not take Tylenol and ibuprofen together if you are taking any other medications for pain without first checking with a doctor. Some medicines, like cold medicine, contain ibuprofen or acetaminophen, and taking more puts you at risk for an overdose.
1 Motrin may not be given more than four times within 24 hours. 2  Tylenol may not be given more than six times within 24 hours. 3  Check for interactions between Tylenol and Motrin and any other medications you may be taking with an interaction checker such as the one found on drugs.com.  Tylenol dosage and safety.