anything done or to be done; anything requiring action or effort; business; concern: an affair of great importance. 2. affairs, matters of commercial or public interest or concern; the transactions of public or private business or finance:
Hyperlactatemia is defined as a persistent, mild to moderate (2-4 mmol/L) increase in blood lactate concentration without metabolic acidosis, whereas lactic acidosis is characterized by persistently increased blood lactate levels (usually >5 mmol/L) in association with metabolic acidosis.
Clinical Significance. Lactic acid is the endproduct of the anaerobic metabolism of glucose. The blood lactic acid concentration is affected by its production in muscle cells and erythrocytes and its rate of metabolism in the liver.During exercise, blood lactate can increase up to ten times of normal levels.To view specimen requirements and codes please Select a regional laboratory.linical Significance. Lactic acid is the endproduct of the anaerobic metabolism of glucose. The blood lactic acid concentration is affected by its production in muscle cells and erythrocytes and its rate of metabolism in the liver.