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Inhibitors are a serious medical problem that can occur when a person with hemophilia has an immune response to treatment with clotting factor concentrates. The immune system defends the body from harmful germs and viruses.
Inhibitors are drugs that work by forming an enzyme-inhibitor complex, which impedes the ability of the enzyme-substrate complex to form. The most successful treatments for HIV have resulted from using inhibitors for the two enzymes reverse transcriptase (step 3 above) and protease (step 7 above).his class of drug acts by inhibiting protease, the enzyme required by HIV to cut its protein into the proper segments to assemble new viral particles. Protease inhibitors, used in combination with two reverse transcriptase inhibitors, have proven to be quite successful.