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How to Take PRISTIQ. Most people start with a once-daily 50-mg dose of PRISTIQ (taken with or without food). Your doctor may keep you on your starting dose throughout your treatment.Talk to your doctor about any health conditions you may have, as your dose might be affected.PRISTIQ should be taken at the same time each day and always swallowed whole, since the tablets are time released.our doctor may keep you on your starting dose throughout your treatment. Talk to your doctor about any health conditions you may have, as your dose might be affected. PRISTIQ should be taken at the same time each day and always swallowed whole, since the tablets are time released.
1 Initiate aspirin (75â325 mg once daily) and continue in combination with Plavix [see Clinical Studies (14.1)] . 2  For patients with STEMI, the recommended dose of Plavix is 75 mg once daily orally, administered in combination with aspirin (75â325 mg once daily), with or without thrombolytics.