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They can weigh anywhere from 110 pounds to the 343 pounds of Zorba, the world's largest dog, although most Mastiff males weigh around 160-230 pounds and females around 120-170 pounds.
Generally, at 3 months of age a male English Mastiff puppy weighs around â¦ 45 pounds, and a female around 39 pounds.Your vet would be able to tell you if your puppy was over or under weight.2 people found this useful.our puppy's size really depends on the size of it's parents, and if your puppy is male, or female. Generally, at 3 months of age a male English Mastiff puppy weighs around â¦ 45 pounds, and a female around 39 pounds. Your vet would be able to tell you if your puppy was over or under weight. 2 people found this useful.