A regulatory framework Although common in other process manufacturing industries (e.g., food and chemicals), continuous processing is at a nascent stage in the pharmaceutical industry, where batch manufacturing is the prevailing mode.
When the motor neurons in the brainstem are affected (bulbar ALS), the muscles used in speech and swallowing are impaired. ALS only affects muscles that are moved voluntarily (such as those in the mouth or arm) and does not impact those muscles involved in involuntary movements, such as digestion.
Eventually, people with ALS lose control of their diaphragm, the muscles in the chest that help you breathe. Then they can't breathe on their own and will need to be on a breathing machine. The loss of breathing causes many people with ALS to die within 3 to 5 years after they're diagnosed. Yet some people can live more than 10 years with the disease. People with ALS can still think and learn. They have all of their senses -- sight, smell, hearing, taste, and touch.