1 The first bomb dropped on Hiroshima was made from uranium. 2  The bomb dropped on Nagasaki was made from plutonium, which was even more powerful than uranium. 3  It is thought that at least 135,000 people died from the Hiroshima explosion and another 70,000 in Nagasaki.
Pharmacokinetic parameters of paclitaxel following 3- and 24-hour infusions of TAXOL at dose levels of 135 and 175 mg/m2 were determined in a Phase 3 randomized study in ovarian cancer patients and are summarized in the following table.
Following endoscopic haemostasis, patients received either 80 mg esomeprazole as an intravenous infusion over 30 minutes followed by a continuous infusion of 8 mg per hour or placebo for 72 hours. After the initial 72 hour period, all patients received open label 40 mg oral Nexium for 27 days for acid suppression.