Genetic variation comes from several sources. Genetic variation comes from two main sources: mutation and recombination. â¢ Mutation A mutation is a random change in the DNA of a gene. This change can form a new allele. Mutations in reproductive cells can be passed on to offspring. This increases the genetic variation in the gene pool.
The medial collateral ligament (MCL) is a broad, thick band that runs down the inner part of the knee, from the femur (thighbone) to about four to six inches from the top of the tibia (shinbone).The MCL's primary function is to prevent the leg from over-extending inward, but it also is part of the mechanism that stabilizes the knee and allows it to ...
MCL Knee Ligament Injury Explained. The Medial Collateral Ligament is the knee ligament located on the inner side of the knee joint. It links the thigh bone and the shin bone. A knee ligament injury is referred to as a sprain, and this knee injury can occur if the knee is twisted or subject to force from an opponent during sport. The Medial Collateral Ligament is the large ligament on the inside of the knee that links the thigh bone and the shin bone. 1  A first degree sprain is damage to only a few ligament fibres.  A second degree sprain is damage to a more extensive number of ligament fibres, but the ligament remains intact.