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Irritating Skin Rashes: 13 Possible Causes. Not typically serious, but always irritating and embarrassing, skin rashes can be caused by a number of factorsâsuch as environment, infection, stress, heat, allergens, immune system disorders, and medication.
Impetigo is common bacterial infection that also can cause a rash on the face, often affecting the mouth and lips. Oral thrush (overgrowth of yeast in the mouth) can also cause lip irritation. Most dermatologists will easily be able to diagnose these types of lip rashes that are caused by pathogens.