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Irritating Skin Rashes: 13 Possible Causes. Not typically serious, but always irritating and embarrassing, skin rashes can be caused by a number of factorsâsuch as environment, infection, stress, heat, allergens, immune system disorders, and medication.
Some rashes occur only on the breast. Causes of rash that occur only on the breast may include: 1  Breast abscess. 2  Inflammatory breast cancer. 3  Mammary duct ectasia.  Mastitis â an infection in breast tissue that most commonly affects women who are breast-feeding.