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Although the starting dose for people with panic disorder, post-traumatic stress disorder, or social anxiety disorder is typically 25 mg daily, healthcare providers often increase that dose to 50 mg daily.fter a week, your healthcare provider will likely increase the dose to 50 mg of Zoloft once a day. He or she may also choose to increase the Zoloft dosage if symptoms continue, or decrease the dose if side effects occur.
How long does Zoloft stay in your body?   Zoloft has a half-life of 1 day - that means for every day that passes without taking zoloft, the level in the blood falls by 50%. So, after one day, the blood level woâ¦uld be reduced by 50%; after 2 days, 25%; after 3 days, 12.5%, and so on.