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Cervical cancer is caused by severe abnormal changes in the cells of the cervix. Most precancerous or cancerous cell changes occur in the cervix at the transformation zone, because these cells normally undergo constant change.
Every year, cervical cancer affects an estimated 500,000 women worldwide. According to the American Cancer Society, infection with human papilloma virus (HPV) is the main risk factor for cervical cancer.hile virtually all women with cervical cancer are infected with HPV, very few women with HPV actually develop cervical cancer. For this reason, it is believed that other factors contribute to the development of cervical cancer.