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NSAIDs are also used to treat non-inflammatory conditions such as migraine, period pain and postoperative pain, and to reduce fever. Aspirin is an NSAID with âblood-thinningâ properties. It can be used in low doses to reduce the risk of heart attack and stroke in high-risk patients.
NSAIDs also may cause swelling of the arms and legs due to the retention of fluid from their renal effects. The most serious side effects are ulcers, bleeding, kidney failure, and, rarely, liver failure. Individuals allergic to NSAIDs may experience shortness of breath after taking an NSAID and may experience a similar reaction when other NSAIDs are taken.