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NSAIDs are also used to treat non-inflammatory conditions such as migraine, period pain and postoperative pain, and to reduce fever. Aspirin is an NSAID with âblood-thinningâ properties. It can be used in low doses to reduce the risk of heart attack and stroke in high-risk patients.
Even Naproxen Risky at High Dose. Our results suggest that all NSAIDs have harmful effects in heart-failure patients, even naproxen at high doses. Naproxen is probably the best of the bunch, but it still increases fluid retention, which is bad news for heart-failure patients, Gislason added.