The distinction between graduate school and professional school is somewhat like the distinction between basic science and applied science; the differences lie in the focus. In graduate school, students focus primarily on mastering a particular field of study.
Protein deglycase DJ-1, also known as Parkinson disease protein 7, is a protein which in humans is encoded by the PARK7 gene.ARK7 belongs to the peptidase C56 family of proteins. The protein structures of human protein DJ-1, Escherichia coli chaperone Hsp31 and an Archaea protease are evolutionarily conserved.
Four chromosomal loci (PARK2, PARK6, PARK7, and PARK9) associated with autosomal recessive, early onset parkinsonism are known. We mapped the PARK7 locus to chromosome 1p36 in a large family from a genetically isolated population in the Netherlands, and confirmed this linkage in an Italian family.By positional cloning within the refined PARK7 critical region we recently identified mutations in the DJ-1 gene in the two PARK7-linked families.J-1(PARK7), a novel gene for autosomal recessive, early onset parkinsonism. Bonifati V, Rizzu P, Squitieri F, Krieger E, Vanacore N, van Swieten JC, Brice A, van Duijn CM, Oostra B, Meco G, Heutink P.