Genetic variation comes from several sources. Genetic variation comes from two main sources: mutation and recombination. â¢ Mutation A mutation is a random change in the DNA of a gene. This change can form a new allele. Mutations in reproductive cells can be passed on to offspring. This increases the genetic variation in the gene pool.
The medial collateral ligament (MCL) is a broad, thick band that runs down the inner part of the knee, from the femur (thighbone) to about four to six inches from the top of the tibia (shinbone).The MCL's primary function is to prevent the leg from over-extending inward, but it also is part of the mechanism that stabilizes the knee and allows it to ...
Causes and Risk Factors. Tears to the lateral collateral ligament most often occur from a direct blow to the inside of the knee. This can stretch the ligaments on the outside of the near too far and may cause them to tear.reatments. Lateral collateral ligament tears do not heal as well as medial collateral ligament tears do. Grade 3 lateral collateral ligament tears may require surgery. In some cases, all that is required is rest, wearing a brace, taking pain relievers such as ibuprofen and having physical therapy.