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Although it is no bigger than a pea, the pituitary gland, located at the base of the brain just beneath the hypothalamus, is considered the most important part of the endocrine system. It's often called the master gland because it makes hormones that control several other endocrine glands.
What brain structure controls the pituitary gland? The portion of the brain that controls the pituitary gland is known  as the hypothalamus. The pituitary gland is responsible for all the  functions in the body.