Boucle yarn is a loose, three ply yarn with a characteristic curly appearance. Used in weaving, knitting, and crocheting, boucle...
Cold agglutinins are antibodies that cause clumping or agglutination of RBCs at cold temperatures in individuals with certain conditions or who are infected by particular organisms. Cold agglutinins are associated with Mycoplasma pneumoniae infection. M. pneumoniae has i antigen specificity to human RBC membranes. Fetal cells largely contain i antigens, but by 18 mo most cells carry the I antigen.
Primary cold agglutinin disease is usually associated with monoclonal cold-reacting autoantibodies. Primary cold agglutinin disease is chronic and occurs after the fifth decade of life, with a peak incidence in the seventh and eighth decades. (See Epidemiology.) Secondary cold agglutinin disease may be associated with either monoclonal or polyclonal cold-reacting autoantibodies.