Trailhead North provides dedicated desks, conference rooms and integrated space for entrepreneurs. Located in the 8th Street Marketplace in the heart of BoDo and Boise's tech corridor.
1. In some cases, the cofactor completes the active site of the enzyme or modifies it in such a manner that substrate binding can ensue. 2. The cofactor acts as a donor of electrons or atoms to the substrate and following the reaction is returned to its former state.
Enzyme changes shape by induced fit upon substrate binding to form enzyme-substrate complex. Hexokinase has a large induced fit motion that closes over the substrates adenosine triphosphate and xylose. Binding sites in blue, substrates in black and Mg2+ cofactor in yellow.