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Certain heart diseases. Heart diseases, including aortic valve disease, left heart failure, mitral valve disease, and congenital heart disease, can also cause pulmonary hypertension. Thromboembolic disease. A blood clot in a large pulmonary artery can result in the development of pulmonary hypertension.
Pulmonary hypertension is diagnosed if the pressure in the right heart catheterization is greater than 25mmHg. Depending on how high the pressure is, the condition may be classified as mild, moderate, or severe pulmonary hypertension.