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Cover up any plants in your garden that you want to keep safe from Roundup. Any type of plastic covering, such as a tarp or old kitchen tablecloth, will do. Roundup is a nonselective herbicide, meaning it will kill any plants it comes into contact with.
How Roundup Works. The primary herbicidal compound in Roundup is glyphosate, which has the chemical name N-(phosphonomethyl) glycine. When you apply Roundup to a plant's foliage, the plant tissues absorb the glyphosate and it moves throughout the plantâs system.As it travels systemically, glyphosate hinders a plantâs ability to synthesize the amino acids that regulate plant growth and the plant dies.f youâre planting lawn grasses, herbs, fruits or vegetables, wait for three days after applying these Roundup products -- except for Roundup Weed & Grass Killer Sure Shot Foam -- before you replant the treated area.