On average, the life expectancy of peritoneal mesothelioma patients is 12 months. However, multiple studies have shown that patients who have cytoreduction with HIPEC experience significantly longer survival times. Many patients now survive up to 5 years and some even live beyond 7 years.
It was written by co-creator Mark Gatiss, who also portrays Mycroft Holmes, Sherlock's brother in the series, and was directed by Paul McGuigan. The episode is a contemporary adaptation of The Hound of the Baskervilles, one of Sir Arthur Conan Doyle 's most famous works.
In the climax to the three-part series, Sherlock Holmes, played by Tinker Tailor Soldier Spy star Benedict Cumberbatch, stood on the roof of St Bartholomewâs hospital in central London and telephoned his best friend and side-kick Dr Watson, played by The Officeâs Martin Freeman, to bid him farewell.