Letâs look at ferns as an example of alternation of generations. The fern plants you see out in the woods, or in a garden, or by a river are sporophytes. They produce spores. If you turn over a fern frond (thatâs just a fancy word for leaf), sometimes youâll see little circles all over the underside of the leaf.
Tricyclic Antidepressant (TCA) Overdose. California Poison Control 1-800-876-4766. Pediatric considerations. Low toxicity threshold of TCAs. Therapeutic doses range from 2-4 mg/kg/d. Toxicity is observed at doses of 10-20 mg/kg. Ingestion of only two 50-mg tablets in a 10-kg toddler can be sufficient. to produce symptoms of toxicity.
1. Theory. TCA is an analog of acetic acid in which the three hydrogen atoms of the methyl carbon have been replaced with chlorine atoms. TCA is a relatively weak acid so it cannot hydrolyze the peptide bonds of proteins, but it does maintain an acidic pH in water.Addition of TCA to proteins in an aqueous solution disrupts the hydrogen-bonded water molecules (hydration sphere) surrounding a protein.These protein molecules no longer remain soluble and can be recovered by centrifugation.. Theory. TCA is an analog of acetic acid in which the three hydrogen atoms of the methyl carbon have been replaced with chlorine atoms. TCA is a relatively weak acid so it cannot hydrolyze the peptide bonds of proteins, but it does maintain an acidic pH in water.