Acromegaly (hypersomatotropism) is an endocrine disorder characterized by progestin-induced hypersecretion of growth hormone (GH) by mammary hyperplasia, with resultant overgrowth of the soft tissue, bone, and viscera. In humans and cats, acromegaly is commonly caused by pituitary adenomas producing GH. Rare cases of pituitary adenomas resulting in acromegaly have been reported in dogs, but acromegaly is usually caused by GH production at hyperplastic mammary glands or mammary adenocarcinoma.
These pro-early neuter studies were not carried out long enough to evaluate the risk of cancer. In my experience, dogs neutered under 6 months develop less obesity and donât establish some of the âmaleâ behaviors that neutering is meant to treat. They are also less likely to jump a fence, fight, or get hit by a car.
Spay ing and neutering puppies is the responsible thing to do, and it's important to know when to neuter a puppy. When love is in the air, the dogs know it. Girl pups mature more quickly than you might think. They can become pregnant as early as five or six months of age, and most dogs can produce two litters a year.