With venom capable of killing a full gown elephant, the King Cobra is the most poisonous snake known to the world. The King cobraâs venom also contains a unique protein called ohanin. Ohanin is being used today in the form of a painkiller that is 20 times more potent than morphine.
Eluxadoline is a Î¼- and Îº-opioid receptor agonist and Î´-opioid receptor antagonist that acts locally in the enteric nervous system, possibly decreasing adverse effects on the central nervous system.ollowing a 100 mg dose of eluxadoline, the Cmax was about 2 to 4 ng/ml and AUC was 12-22 ng.h/ml. Eluxadoline has linear pharmacokinetics with no accumulation upon repeated twice daily dosing. Its plasma protein binding was 81% and its half life was 3.7 to 6 hours and it was excreted mainly in feces.
Facebook Twitter Pinterest. DUBLIN, May 27, 2015 /PRNewswire/ -- Actavis plc (NYSE: ACT) announced today that VIBERZIâ¢ (eluxadoline) was approved by the Food and Drug Administration (FDA) as a twice-daily, oral treatment for adults suffering from irritable bowel syndrome with diarrhea (IBS-D).he FDA's approval of VIBERZI is the first step to providing physicians with a new, evidence-based, treatment option for their adult patients with IBS-D, said David Nicholson, Executive Vice President, Actavis Global Brands R&D.