Boucle yarn is a loose, three ply yarn with a characteristic curly appearance. Used in weaving, knitting, and crocheting, boucle...
Cold agglutinins are antibodies that cause clumping or agglutination of RBCs at cold temperatures in individuals with certain conditions or who are infected by particular organisms. Cold agglutinins are associated with Mycoplasma pneumoniae infection. M. pneumoniae has i antigen specificity to human RBC membranes. Fetal cells largely contain i antigens, but by 18 mo most cells carry the I antigen.
In cold agglutinin disease, the antibody is an IgM, usually monoclonal, with kappa (Îº) or lambda (Î») light chains. In chronic cold agglutinin disease, the antibody is usually directed against the I antigen on the membrane of normal adult RBCs.