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Birth defects (or congenital defects) are defects in a baby at birth, or which develop in the first month of life. There are two main types of congenital defect. The first is caused by genetic abnormalities, which are hereditary. The second is caused by conditions (such as infectious diseases) which a baby gets from its mother. Sometimes doctors can find out that a baby has a congenital disorder before its birth.
Neural tube defects (NTDs) are among the most common birth defects contributing to infant mortality and serious disability. NTDs, which include anencephaly, spina bifida, and encephalocele, occur in approximately 1 of 1000 births in the United States. An estimated 4000 pregnancies are affected with NTDs each year.