Acromegaly (hypersomatotropism) is an endocrine disorder characterized by progestin-induced hypersecretion of growth hormone (GH) by mammary hyperplasia, with resultant overgrowth of the soft tissue, bone, and viscera. In humans and cats, acromegaly is commonly caused by pituitary adenomas producing GH. Rare cases of pituitary adenomas resulting in acromegaly have been reported in dogs, but acromegaly is usually caused by GH production at hyperplastic mammary glands or mammary adenocarcinoma.
These pro-early neuter studies were not carried out long enough to evaluate the risk of cancer. In my experience, dogs neutered under 6 months develop less obesity and donât establish some of the âmaleâ behaviors that neutering is meant to treat. They are also less likely to jump a fence, fight, or get hit by a car.
In general, dogs neutered before they go into puberty grow a bit bigger than those neutered after puberty because testosterone is involved in bone growth; sometimes that growth is preferable and sometimes itâs not. Most dogs are sexually mature by the age of five or six months (the blink of an eye).n general, dogs neutered before they go into puberty grow a bit bigger than those neutered after puberty because testosterone is involved in bone growth; sometimes that growth is preferable and sometimes itâs not. Most dogs are sexually mature by the age of five or six months (the blink of an eye).