Boucle yarn is a loose, three ply yarn with a characteristic curly appearance. Used in weaving, knitting, and crocheting, boucle...
Cold agglutinins are antibodies that cause clumping or agglutination of RBCs at cold temperatures in individuals with certain conditions or who are infected by particular organisms. Cold agglutinins are associated with Mycoplasma pneumoniae infection. M. pneumoniae has i antigen specificity to human RBC membranes. Fetal cells largely contain i antigens, but by 18 mo most cells carry the I antigen.
Clumped red cells and those that are not clumped but are in the vicinity spread poorly on peripheral smears and may resemble spherocytes. The cold agglutinin titer was positive at 1:640 000 and was the âMâ component noted above. A diagnosis of cold agglutinin hemolytic anemia was made.