Acromegaly (hypersomatotropism) is an endocrine disorder characterized by progestin-induced hypersecretion of growth hormone (GH) by mammary hyperplasia, with resultant overgrowth of the soft tissue, bone, and viscera. In humans and cats, acromegaly is commonly caused by pituitary adenomas producing GH. Rare cases of pituitary adenomas resulting in acromegaly have been reported in dogs, but acromegaly is usually caused by GH production at hyperplastic mammary glands or mammary adenocarcinoma.
These pro-early neuter studies were not carried out long enough to evaluate the risk of cancer. In my experience, dogs neutered under 6 months develop less obesity and donât establish some of the âmaleâ behaviors that neutering is meant to treat. They are also less likely to jump a fence, fight, or get hit by a car.
We recommend that puppies be neutered at five to six months of age. Ifthe puppy is to be shown or used for breeding, it should still be neutered at five or six years old. Male dogs have been known to wander many miles from their neighborhoods, led instinctively by their attraction to female dogs in heat.e recommend that puppies be neutered at five to six months of age. Ifthe puppy is to be shown or used for breeding, it should still be neutered at five or six years old. Male dogs have been known to wander many miles from their neighborhoods, led instinctively by their attraction to female dogs in heat.