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Problem #1: Osteoarthritis. Often referred to as the âwear and tearâ arthritis, osteoarthritis is caused by the wearing down of the protective cartilage that covers the ends of your bones. On your foot, it is most likely to strike at the joints where your toes meet your foot (metatarso-phalangeal or inter-phalangeal).
Infections Between the Toes. When a rash or wound develops between toes, there are a few possible causes. In most cases, the cause is a fungal infectionâthe same organism that causes athlete's foot. Another cause is a bacterial infection, which is one reason that some foot infections don't seem to heal with anti-fungal creams.