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The common cold is a viral infectious disease that infects the upper respiratory system. It is also known as acute viral rhinopharyngitis, or acute coryza. Being the most common infectious disease in humans, the cold is mainly caused by coronaviruses or rhinoviruses. The human body can never build up resistance to all the viruses that can cause the common cold.
Definition. 1  The common cold is a viral infection of the upper respiratory system, including the nose, throat, sinuses, eustachian tubes, trachea, larynx, and bronchial tubes. Although more than 200 different viruses can cause a cold, 30-50% are caused by a group known as rhinoviruses.