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How alcohol and ecstasy affect ADH. Alcohol suppresses ADH production. This causes the kidneys to produce more dilute urine. It can lead to dehydration. Ecstasy increases ADH production. This causes the kidneys to reabsorb water. It can result in the body having too much water.
Alcohol inhibits the pituitary secretion of anti-diuretic hormone (ADH), which acts on the kidney to reabsorb water. Alcohol acts on the hypothalamus/pituitary to reduce the circulating levels of ADH. When ADH levels drop, the kidneys do not reabsorb as much water; consequently, the kidneys produce more urine. 1. 2. â¦.