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Thoracentesis is a procedure to remove fluid from the space between the lungs and the chest wall called the pleural space. It is done with a needle (and sometimes a plastic catheter) inserted through the chest wall. Ultrasound pictures are often used to guide the placement of the needle. This pleural fluid may be sent to a lab to determine what may be causing the fluid to build up in the pleural space.
A procedure called thoracentesis is used to get a sample of pleural fluid. The health care provider examines the sample to look for: 1  Cancerous (malignant) cells. 2  Other types of cells (for example blood cells)  Levels of glucose, protein and other chemicals.