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How alcohol and ecstasy affect ADH. Alcohol suppresses ADH production. This causes the kidneys to produce more dilute urine. It can lead to dehydration. Ecstasy increases ADH production. This causes the kidneys to reabsorb water. It can result in the body having too much water.
There are a variety of disorders, conditions, and medications that can affect either the amount of ADH released or the kidneys' response to it. ADH deficiency and excess can cause acute and chronic symptoms that, in rare cases, may become life-threatening.If there is too little ADH or the kidneys do not respond to ADH, then too much water is lost through the kidneys, the urine produced is more dilute than normal, and the blood becomes more concentrated.DH is normally released by the pituitary in response to sensors that detect an increase in blood osmolality (number of dissolved particles in the blood) or decrease in blood volume. The kidneys respond to ADH by conserving water and producing urine that is more concentrated.