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Irritating Skin Rashes: 13 Possible Causes. Not typically serious, but always irritating and embarrassing, skin rashes can be caused by a number of factorsâsuch as environment, infection, stress, heat, allergens, immune system disorders, and medication.
Allergies and autoimmune disorders are other possible causes of a genital rash: 1  Contact dermatitis is a common type of rash caused when skin comes into contact with an allergen or with an irritant like a harsh chemical substance. Contact dermatitis is a common type of rash caused when skin comes into contact with an allergen or with an irritant like a harsh chemical substance. 2  Latex is an allergen that may produce a rash in the genital area because many condoms are made of this material. 3  Psoriasis is a common skin condition.