Genetic variation comes from several sources. Genetic variation comes from two main sources: mutation and recombination. â¢ Mutation A mutation is a random change in the DNA of a gene. This change can form a new allele. Mutations in reproductive cells can be passed on to offspring. This increases the genetic variation in the gene pool.
The medial collateral ligament (MCL) is a broad, thick band that runs down the inner part of the knee, from the femur (thighbone) to about four to six inches from the top of the tibia (shinbone).The MCL's primary function is to prevent the leg from over-extending inward, but it also is part of the mechanism that stabilizes the knee and allows it to ...
Treatment of Collateral Ligament Injuries. Most injuries to the collateral ligaments will heal with immobilizing the knee joint in a cast or brace for 4-6 weeks. An isolated injury to the lateral collateral ligament or medial collateral ligament usually does not require surgical repair or reconstruction.The initial treatment for a collateral ligament injury focuses on reducing the inflammation (pain and swelling) in the knee.he medial collateral ligament can tear in the middle of the ligament, where the medial collateral ligament attaches to the tibia, or where the medial collateral ligament attaches to the femur. If the force against the knee or leg is great enough other ligaments can tear as well.