The combination drug, formerly known as LCZ696, is the first approved agent in the angiotensin receptor-neprilysin inhibitor (ARNI) class and exerts its effect within and beyond the renin-angiotensin system.
Hatred (or hate) is a deep and emotional extreme dislike. It can be directed against individuals, groups, entities, objects, behaviors, or ideas. Hatred is often associated with feelings of anger, disgust and a disposition towards hostility.
Mean, low, base, sordid, and vile all refer to ignoble characteristics worthy of dislike, contempt, or disgust. Mean suggests pettiness and small-mindedness: to take a mean advantage. Low suggests coarseness and vulgarity: low company. Base suggests selfish cowardice or moral depravity: base motives.