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In addition, the neurotransmitter can bind to any one of the nearby smooth muscle cells, a flexibility not found in the NMJ. The chemicals that influence smooth muscle cells: As you'll recall, there is only one neurotransmitter released at the neuromuscular junction-acetylcholine.
Alpha motor neurons (also called lower motor neurons) innervate skeletal muscle and cause the muscle contractions that generate movement. Motor neurons release the neurotransmitter acetylcholine at a synapse called the neuromuscular junction. Thus, there is a one-to-one relationship between a muscle and a motor neuron pool. 2  Each individual muscle fiber in a muscle is innervated by one, and only one, motor neuron (make sure you understand the difference between a muscle and a muscle fiber). 3  A single motor neuron, however, can innervate many muscle fibers.