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Irritating Skin Rashes: 13 Possible Causes. Not typically serious, but always irritating and embarrassing, skin rashes can be caused by a number of factorsâsuch as environment, infection, stress, heat, allergens, immune system disorders, and medication.
Medications are a frequent cause of rash. Basically, any medication can cause a rash to develop in any person. Common medications that cause a rash include antibiotics, and medications for high blood pressure and cholesterol. Rarely, cancer of the skin can present as a skin rash.