On average, the life expectancy of peritoneal mesothelioma patients is 12 months. However, multiple studies have shown that patients who have cytoreduction with HIPEC experience significantly longer survival times. Many patients now survive up to 5 years and some even live beyond 7 years.
It was written by co-creator Mark Gatiss, who also portrays Mycroft Holmes, Sherlock's brother in the series, and was directed by Paul McGuigan. The episode is a contemporary adaptation of The Hound of the Baskervilles, one of Sir Arthur Conan Doyle 's most famous works.
1 The 1975 film The Adventure of Sherlock Holmes' Smarter Brother, starring Gene Wilder as Holmes' younger brother Sigerson Holmes, was inspired by Mycroft (he is mentioned, but doesn't appear). 2  Boris Klyuyev played Mycroft Holmes in The Adventures of Sherlock Holmes and Dr. Watson, a Soviet TV series.