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Although it is no bigger than a pea, the pituitary gland, located at the base of the brain just beneath the hypothalamus, is considered the most important part of the endocrine system. It's often called the master gland because it makes hormones that control several other endocrine glands.
Hypothalamus. The hypothalamus is a part of the brain located superior and anterior to the brain stem and inferior to the thalamus. It serves many different functions in the nervous system, and is also responsible for the direct control of the endocrine system through the pituitary gland.he nervous system can control hormone levels through the action of the hypothalamus and its releasing and inhibiting hormones. For example, TRH produced by the hypothalamus stimulates the anterior pituitary to produce TSH. Tropic hormones provide another level of control for the release of hormones.