The Inheritance of Thalassemia. Recall that hemoglobin is the protein that is affected in thalassemia. Hemoglobin is made of heme, alpha globins, and beta globins. At least 9 different genes direct the production of heme. Changes in these genes may lead to disorders of heme production, a group of conditions separate from the thalassemias. Alpha thalassemia occurs when a mutation in the gene that codes for alpha globin results in reduced or absent production of alpha globins. Beta thalassemia occurs with a corresponding change in the beta globin gene. Therefore, the thalassemias are a result of quantitative mutations in the globin genes. Below is a karyotype, a picture of all of an individualâs genetic information as seen through a microscope.
Select another year-range: Washington's Birthday, also known as Presidents' Day, is a federal holiday held on the third Monday of February. The day honors presidents of the United States, including George Washington, the USA's first president. George Washington was the first president of the United States of America.
This year, Presidents Day is February 17, five days before George Washington's birthday. On Monday, the nation celebrates Presidents' Day. Or is it George Washingtonâs Birthday?