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Although the starting dose for people with panic disorder, post-traumatic stress disorder, or social anxiety disorder is typically 25 mg daily, healthcare providers often increase that dose to 50 mg daily.fter a week, your healthcare provider will likely increase the dose to 50 mg of Zoloft once a day. He or she may also choose to increase the Zoloft dosage if symptoms continue, or decrease the dose if side effects occur.
Appetite and sleep energy may get improved in one or two weeks of Zoloft usage while depressive disorders may get resolved in six to eight weeks of usage. How long does Zoloft take to work is usually subjective.