Both Panadeine and Sudafed contain paracetamol, so if you took a full dose of each together you would be exceeding the recommended paracetamol dose. I suppose if you really wa â¦ nted the effects of both pills you could take a half dose (one tablet) of each.3 people found this useful.t won't harm you as long as you keep to the dosages recommended for each. For chronic users, however, this combo made lead to some insomnia. Warning: I was takin â¦ g 10mg oxycodone every 3-4 hours when I took one Sudafed.
What causes scleroderma is still a mystery; sufferers of scleroderma will experience a buildup of collagen in the skin and other organs and this is what leads to the symptoms of the disease.
1 Skin can appear shiny because it's so tight, and movement of the affected area may be restricted.  Fingers or toes. One of the earliest signs of scleroderma is an exaggerated response to cold temperatures or emotional distress, which can cause numbness, pain or color changes in the fingers or toes. Called Raynaud's disease, this condition also occurs in people who don't have scleroderma.