Trailhead North provides dedicated desks, conference rooms and integrated space for entrepreneurs. Located in the 8th Street Marketplace in the heart of BoDo and Boise's tech corridor.
1. In some cases, the cofactor completes the active site of the enzyme or modifies it in such a manner that substrate binding can ensue. 2. The cofactor acts as a donor of electrons or atoms to the substrate and following the reaction is returned to its former state.
In other words the reaction can be reversible. The enzyme can continue locking with a substrate and continue it's catalysts activity. If the pH is too high or too low it can change the shape of the enzyme. The ionic bonds that hold the shape of the enzyme are broken changing the 3D shape of the enzyme.