Letâs look at ferns as an example of alternation of generations. The fern plants you see out in the woods, or in a garden, or by a river are sporophytes. They produce spores. If you turn over a fern frond (thatâs just a fancy word for leaf), sometimes youâll see little circles all over the underside of the leaf.
Tricyclic Antidepressant (TCA) Overdose. California Poison Control 1-800-876-4766. Pediatric considerations. Low toxicity threshold of TCAs. Therapeutic doses range from 2-4 mg/kg/d. Toxicity is observed at doses of 10-20 mg/kg. Ingestion of only two 50-mg tablets in a 10-kg toddler can be sufficient. to produce symptoms of toxicity.
The primary cause of ARA-C toxicity is considered to be a clinical consequence of cytokine network activation, which results in alveolar damage and increased vascular permeability, leading to capillary leakage syndrome (5), (6), (9).