1 The first bomb dropped on Hiroshima was made from uranium. 2  The bomb dropped on Nagasaki was made from plutonium, which was even more powerful than uranium. 3  It is thought that at least 135,000 people died from the Hiroshima explosion and another 70,000 in Nagasaki.
Pharmacokinetic parameters of paclitaxel following 3- and 24-hour infusions of TAXOL at dose levels of 135 and 175 mg/m2 were determined in a Phase 3 randomized study in ovarian cancer patients and are summarized in the following table.
This medication may be given as a tablet taken by mouth, an injection into a vein (intravenous), or an injection into a muscle (intramuscular). Intravenous injections usually take up to 20 minutes. Sometimes, methotrexate may be injected into the spinal cord in order to kill cancer cells in that region. The exact approach, dose, and schedule varies depending on the type of cancer being treated, the extent of disease, and other factors.