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Irritating Skin Rashes: 13 Possible Causes. Not typically serious, but always irritating and embarrassing, skin rashes can be caused by a number of factorsâsuch as environment, infection, stress, heat, allergens, immune system disorders, and medication.
Drug side effect causes of Face rash. The following drugs, medications, substances or toxins may possibly cause Face rash as a side effect. [ See detailed list of 5 drug side effect causes of Face rash 1  ]. Clonidine transdermal patch. 2  Catapres transdermal patch. 3  Catapres-TTS-1 transdermal patch. 4  Catapres-TTS-2 transdermal patch.