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Certain heart diseases. Heart diseases, including aortic valve disease, left heart failure, mitral valve disease, and congenital heart disease, can also cause pulmonary hypertension. Thromboembolic disease. A blood clot in a large pulmonary artery can result in the development of pulmonary hypertension.
Diuretics or âwater pillsâ in the treatment of pulmonary hypertension. Diuretics are commonly used to help treat heart failure. Because the right ventricle of pulmonary arterial hypertension patients is straining to pump against the increased pressures in the pulmonary arteries, they have the same volume management problem.