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No one really knows what causes asthma. What we do know is that asthma is a chronic inflammatory disease of the airways. The causes of asthma symptoms can vary from person to person. Still, one thing is consistent with asthma: when airways come into contact with an asthma trigger, the airways become inflamed, narrow, and fill with mucus.
An asthma flare-up (or attack) is when a person's symptoms get worse. 1  During a flare-up, a person might have: 2  trouble breathing. 3  a tight chest. 4  a whistling sound when breathing (wheezing) 5  a cough.