[Na][NH2] + H2O NH3 + [Na][OH]. Water and alcohols are similar as Bronsted acids and they also have similar acid dissociation constants. The conjugate base of an alcohol is called an alkoxide. Above we see the dissociation of methanol to a solvated proton and the conjugate base methoxide.he hydrogen is a little less electronegative than the carbon so a C-H bond is slightly polarized with more electron density on carbon. Excess electron density on a carbon adjacent to a negatively charged oxygen atom (in the alkoxide) destabilizes the conjugate base and makes the acid a little weaker.
Conventional treatment of kennel cough in dogs depends on the severity of the infection. For mild cases of kennel cough, antibiotics may or may not be administered. If administered, the drugs of choice are the tetracyclines and trimethoprimsulfa and the antibiotics are continued for 7 to 10 days. In addition, cough suppressants may also be used to treat mild cases.
Antibiotics are the mainstay of treatment in S pneumoniae infections. Until the 1970s, essentially all pneumococcal isolates were sensitive to easily achievable levels of most commonly used antibiotics, including penicillins, macrolides, clindamycin, cephalosporins, rifampin, vancomycin, and trimethoprim-sulfamethoxazole.