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Although the starting dose for people with panic disorder, post-traumatic stress disorder, or social anxiety disorder is typically 25 mg daily, healthcare providers often increase that dose to 50 mg daily.fter a week, your healthcare provider will likely increase the dose to 50 mg of Zoloft once a day. He or she may also choose to increase the Zoloft dosage if symptoms continue, or decrease the dose if side effects occur.
Common Zoloft side effects may include: drowsiness, tiredness, feeling anxious or agitated; indigestion, nausea, diarrhea, loss of appetite; sweating; tremors or shaking; sleep problems (insomnia); or. decreased sex drive, impotence, or difficulty having an orgasm. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. See also: Side effects (in more detail) Zoloft dosing information. Usual Adult Dose of Zoloft for Depression: Initial dose: 50 mg orally once a day