6. Stay on schedule. Try going to sleep at the same time every night, as well as waking up at the same time every morning. This trains your body to want to go to bed when it's time for you to go to bed, helping you get to sleep easier.
Prostaglandins provide a protective barrier that prevent the stomach from digesting itself. If there is a break in the protective barrier, mucosal injury occurs. Injury worsen by histamine release and vagal nerve stimulation. Hydrochloric acid diffuse back into the mucosa and injure small vessels. This causes edema, hemorrhage, and erosion of the stomach's lining.
How These Medications Work. Both PPIs and H2 Blockers suppress gastric acid secretion. They are different, however, in how they do this. While PPIs shut down the proton pumps in the stomach, H2 Blockers work by blocking the histamine receptors in acid-producing cells in the stomach. Proton Pump Inhibitors (PPIs) The proton pump is a molecule in certain cells of the stomach.