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Total iron binding capacity (TIBC) is a blood test to see if you have too much or too little iron in the blood. Iron moves through the blood attached to a protein called transferrin. This test helps your doctor know how well that protein can carry iron in the blood.
PBC is a relatively rare disease, affecting up to 1 in 3â4,000 people. It is much more common in women, with a sex ratio of at least 9:1 female to male. The condition has been recognised since at least 1851 and was named primary biliary cirrhosis in 1949. Because cirrhosis is a feature only of advanced disease, a change of its name to primary biliary cholangitis was proposed by patient advocacy groups in 2014.