Profound sedation, respiratory depression, coma, and death may result from the concomitant use of Buprenex with benzodiazepines or other CNS depressants (e.g., non-benzodiazepine sedatives/hypnotics, anxiolytics, tranquilizers, muscle relaxants, general anesthetics, antipsychotics, other opioids, alcohol).
The MOU is developed through a process of negotiation and mutual assent, finalized through acceptance of the MOU instrument, and approved by the appropriate agency representatives who signify such approval by signing the MOU.
colleges and universities now offer the MOUS certification program as an elective, including Mississippi State University; North Carolina State University; Southern Oregon State University; Washington State University; the University of California Santa Barbara; the University of Colorado; University of Maryland Eastern Shore; and the University of Wisconsin-Milwaukee.