Both Panadeine and Sudafed contain paracetamol, so if you took a full dose of each together you would be exceeding the recommended paracetamol dose. I suppose if you really wa â¦ nted the effects of both pills you could take a half dose (one tablet) of each.3 people found this useful.t won't harm you as long as you keep to the dosages recommended for each. For chronic users, however, this combo made lead to some insomnia. Warning: I was takin â¦ g 10mg oxycodone every 3-4 hours when I took one Sudafed.
Raynaud's phenomenon[edit] Raynaud's phenomenon is frequently the first manifestation of CREST/lcSSc, preceding other symptoms by years. Stress and cold temperature induces an exaggerated vasoconstriction of the small arteries, arterioles, and thermoregulatory vessels of the skin of the digits.
Scleroderma is a condition in which a type of connective tissue in the body called collagen is overproduced. It can be localized, leading to hardened patches or bands of skin, the tissue that lies immediately below the skin and sometimes the muscles of the arms, legs or forehead.his acronym refers to the group of symptoms that may be found to some degree in most cases of limited cutaneous scleroderma, which generally affects only the arms, fingers, legs, face and neck. CREST symptoms are calcinosis, Raynaud's, esophagus, sclerodactyly, telangiectasias.