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Although the starting dose for people with panic disorder, post-traumatic stress disorder, or social anxiety disorder is typically 25 mg daily, healthcare providers often increase that dose to 50 mg daily.fter a week, your healthcare provider will likely increase the dose to 50 mg of Zoloft once a day. He or she may also choose to increase the Zoloft dosage if symptoms continue, or decrease the dose if side effects occur.
Premenstrual Dysphoric Disorder. ZOLOFT treatment should be initiated with a dose of 50 mg/day, either daily throughout the menstrual cycle or limited to the luteal phase of the menstrual cycle, depending on physician assessment.