With venom capable of killing a full gown elephant, the King Cobra is the most poisonous snake known to the world. The King cobraâs venom also contains a unique protein called ohanin. Ohanin is being used today in the form of a painkiller that is 20 times more potent than morphine.
Eluxadoline is a Î¼- and Îº-opioid receptor agonist and Î´-opioid receptor antagonist that acts locally in the enteric nervous system, possibly decreasing adverse effects on the central nervous system.ollowing a 100 mg dose of eluxadoline, the Cmax was about 2 to 4 ng/ml and AUC was 12-22 ng.h/ml. Eluxadoline has linear pharmacokinetics with no accumulation upon repeated twice daily dosing. Its plasma protein binding was 81% and its half life was 3.7 to 6 hours and it was excreted mainly in feces.
Eluxadoline is a prescription medication used to irritable bowel syndrome with diarrhea (IBS-D) in adults. Eluxadoline belongs to a group of drugs called mu-opioid receptor antaognists.The exact mechanism of eluxadoline in IBS-D is not known, but eluxadoline interacts with opioid receptors in the gut. This medication comes in tablet form and is taken 2 times a day with food.t is not known if eluxadoline crosses into human milk. Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication.