Treatment is usually curative with wide-margin surgical excision but due to the malignant nature of these tumors, recurrence should be considered and regular monitoring is recommended. 1  Gianella P et al (2012) Primary cutaneous undifferentiated round cell tumor with concurrent polymyositis in a dog. Can Vet J 53(5):549-553. Mackowiak II et al (2012) E-cadherin in canine mast cell tumors: Decreased expression and altered subcellular localization in Grade 3 tumors. Vet J 194(3):405-11.
Endocrine glands are glands of the endocrine system that secrete their products, hormones, directly into the blood rather than through a duct.The major glands of the endocrine system include the pineal gland, pituitary gland, pancreas, ovaries, testes, thyroid gland, parathyroid gland, hypothalamus and adrenal glands.The hypothalamus and pituitary gland are neuroendocrine organs.Local chemical messengers, not generally considered part of the endocrine system, include autocrines, which act on the cells that secrete them, and paracrines, which act on a different cell type nearby.he hypothalamus and pituitary gland are neuroendocrine organs. Local chemical messengers, not generally considered part of the endocrine system, include autocrines, which act on the cells that secrete them, and paracrines, which act on a different cell type nearby.
In blood-glucose levels, insulin lowers the concentration of glucose in the blood. The lower blood-glucose level (a product of the insulin secretion) triggers glucagon to be secreted, and repeats the cycle. In order for blood glucose to be kept stable, modifications to insulin, glucagon, epinephrine and cortisol are made.