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Other factors that can sometimes cause phosphate levels to rise include excess vitamin D, decrease in magnesium levels in the body and for women, pregnancy. Low phosphate levels, on the other hand are indicative of hyperparathyroidism, osteomalacia, kidney and liver infections, lack of vitamin D and intense burns.
Results from a full chemistry profile can be used as follows in determining the cause of hyperphosphatemia: 1  Low serum calcium levels along with high phosphate levels: Observed with renal failure, hypoparathyroidism, and pseudohypoparathyroidism. Blood urea nitrogen (BUN) and creatinine values: Help to determine whether renal failure is the cause of hyperphosphatemia.