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You may have an infection. A positive finding of the enzyme leukocyte esterase in urinalysis indicates the presence of white blood cells in the urine. This normally suggests inflammation of some sort, often from a urinary tract infection. A simple dipstick test as part of a urinalysis can detect the presence of this enzyme.
Tests to detect nitrites and leukocyte esterase have become part of a routine urinalysis. Most species of bacteria that colonize in the urine cause nitrates, which are derived from dietary metabolites, to be converted to nitrites. In healthy people, both the urinary nitrite test and the leukocyte esterase (LE) tests are negative. A negative nitrite test does not necessarily mean that the urine is free of all bacteria, particularly if there are clinical symptoms, because some bacteria do not produce nitrites.