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Prophylaxis of gout flares: If the original colchicine dose was 0.6 mg twice daily, 0.6 mg daily or 0.3 mg twice daily should be given. For an original dose of 0.6 mg daily, the adjusted dose is 0.3 mg daily.Treatment of gout flares: Take 1.2 mg Ã 1 dose of colchicine; at least 3 days should elapse before repeating.rophylaxis of gout flares: If the original colchicine dose were 0.6 mg twice daily, 0.3 mg should be given once daily. For an original dose of 0.6 mg daily, the adjusted dose is 0.3 mg every other day.
As with allopurinol treatment, the dose should be slowly increased. The recommended dose of probenecid is 250 mg, twice daily, for the first week, increasing to 500 mg, twice daily, for the second week and then increasing by 500 mg in subsequent months to a maximum of 2000 mg, daily in divided doses.oncurrent administration of low dose NSAIDs (e.g. naproxen 250 mg, twice daily) or colchicine (0.5 mg daily or twice daily) during this two week period, and for the following three to six months (or longer in tophaceous gout), is strongly recommended to help prevent flares.