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Intrinsic muscles. Definition. noun. A group of muscles located within or situated deeper in a structure, in contrast to extrinsic muscles located rather superficially. Supplement. Based on the above definition, the intrinsic muscles refer to the muscles closest to the axial and appendicular skeleton.For example, the intrinsic muscles of the hand are those lying deeper in the hand, such as the interossei and lumbrical muscles.ased on the above definition, the intrinsic muscles refer to the muscles closest to the axial and appendicular skeleton. For example, the intrinsic muscles of the hand are those lying deeper in the hand, such as the interossei and lumbrical muscles.
Answer by Cartmell. Confidence votes 177. Extrinsic muscles are voluntary muscles,external to the eye, that control the direction the eye moves in e.g looking left or right. Intrinsic muscles are within the eye, such as those that control the size of the pupil.Intrinsic muscle is not under voluntary control.xtrinsic muscles are voluntary muscles,external to the eye, that control the direction the eye moves in e.g looking left or right.