1 I-mmersion sensorâ¢ adjusts internal pressures automatically in response to patient weight, morphology and position maintaining the lowest possible interface pressures.  1 in 4 alternating low pressure cycle supports 75% of patient weight all of the time.
What receptors adapt most slowly? Nociceptors are the receptors that adapt most slowly. Other  receptors include smell, touch, and pressure receptors, which adapt  faster than nociceptors. Making the world better, one answer at a time.
Adrenergic receptors can be desensitized and downregulated in certain conditions, such as in chronic heart failure (HF).4 Finally, the relative binding affinities of individual inotropes and vasopressors to adrenergic receptors can be altered by hypoxia5 or acidosis,6 which mutes their clinical effect.