summary gout is a common painful form of arthritis it causes swollen red hot and stiff joints gout happens when uric acid builds up in your body uric acid comes from the breakdown of substances called purines purines are in your body s tissues and in foods such as liver dried beans and peas and anchovies
Systemic diseases that affect the kidneys are called secondary causes of nephrotic syndrome. More than 50 percent of nephrotic syndrome cases in adults have secondary causes, with diabetes being the most common.1.
congenital nephrotic syndrome. At least 170 mutations in the NPHS2 gene have been found to cause congenital nephrotic syndrome. This condition is a kidney disorder that begins in infancy and typically leads to irreversible kidney failure (end-stage renal disease) by early childhood.