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Other factors that can sometimes cause phosphate levels to rise include excess vitamin D, decrease in magnesium levels in the body and for women, pregnancy. Low phosphate levels, on the other hand are indicative of hyperparathyroidism, osteomalacia, kidney and liver infections, lack of vitamin D and intense burns.
PTH causes phosphate loss through the kidneys. Thus, in patients with PTH-mediated hypercalcemia, serum phosphate levels tend to be low. Vitamin D is a steroid hormone that is obtained through the diet or produced by the action of sunlight on vitamin D precursors in the skin.