After 1 week at 10 mg/day, increase the dose to 20 mg/day. However, due to higher plasma levels in lower weight children, the starting and target dose in this group may be 10 mg/day. Consider a dose increase to 20 mg/day after several weeks if insufficient clinical improvement is observed.
About the lake. Lake Koocanusa is 90 miles long and at full pool, 370 feet deep. Although it sounds like an ancient tribal name of some sort, Lake Koocanusa is not an Indian name. A lady named Alice Beers who lived in Rexford, Montana won a contest in 1971 to name the reservoir formed by Libby Dam.
We recommend the following GPK (gallons per Koi) rates based on their size: Small Koi (2 - 8): 100 - 150 gallons. Medium Koi(8 - 14): 250 - 300 gallons. Large Koi(14 - 24): 400 - 500 gallons. Jumbo Koi(24 - 36): 750 - 900 gallons. The GPK estimates are based on long term housing for the Koi. Indoor winter tanks can be small, but must accommodate enough room for the Koi to swim around comfortably.