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The Red Cross is also a leader in research and testing to protect the safety of the blood supply. We were among the first to develop and implement testing for many infectious diseases including, HIV, hepatitis B and C viruses, West Nile virus, and more recently the agent of Chagas disease.
1 Direct Coombs test. A negative test result means that your blood does not have antibodies attached to your red blood cells.  Indirect Coombs test. A negative test result means that your blood is compatible with the blood you are to receive by transfusion. A negative indirect Coombs test for Rh factor (Rh antibody titer) in a pregnant woman means that she has not developed antibodies against the Rh-positive blood of her baby.