1 Around the eyes, cheeks, nose, and forehead in adults and infants.  On the gums and palate inside the mouth of infants; these milia are called Epstein's pearls, and they occur in up to 85% of infants.
Osteochondral lesions can occur after just one traumatic injury or as a result of a series of traumatic episodes. The following signs and symptoms may raise a concern for osteochondral lesions: Prolonged pain in the affected ankle joint triggered by any physical activities. Popping or locking of the ankle joint.
Stiffness, joint pain, and swelling are the earliest symptoms of osteoarthritis. In contrast to inflammatory arthritis, the pain of osteoarthritis is often exacerbated by activity or weight bearing and relieved by rest.Early symptoms are usually of an insidious nature and often do not correlate well with radiographic abnormalities.tiffness, joint pain, and swelling are the earliest symptoms of osteoarthritis. In contrast to inflammatory arthritis, the pain of osteoarthritis is often exacerbated by activity or weight bearing and relieved by rest.