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Delayed sleep phase disorder (DSPD), also known as delayed sleep phase syndrome or delayed sleep phase type, and in the 2014 revision of the International Classification of Sleep Disorders (ICSD-3), delayed sleep-wake phase disorder, is a chronic dysregulation of a person's circadian rhythm (biological clock), compared to the general population and ...
Down syndrome (DS) is the most common cause of mental retardation and malformation in a newborn. It occurs because of the presence of an extra chromosome. It was first described in 1866 by Dr. John L. H. Down (1828â1896), an English physician. Down syndrome occurs about once in every 800 births.