Meticulously directed by Mendes and brilliantly photographed by Conrad Hall, each scene of ROAD TO PERDITION has the composition of an expertly rendered painting. Making effective use of rain, snow, and shadows, the filmmakers create a cinematic world that's as dark, cold, and unforgiving as many of its inhabitants.
People who have severe hemophilia have spontaneous bleeding into the joints and muscles. Hemophilia occurs more commonly in males than in females. The two most common types of hemophilia are hemophilia A (also known as classic hemophilia) and hemophilia B (also known as Christmas disease). People who have hemophilia A have low levels of a blood clotting factor called factor eight (FVIII).
There is a 50% chance of the son having hemophilia. Hemophilia is a recessive gene carried by the X chromosome. The alleles for the mother would be XHXh and for the father XhYâ¦. If the same couple would have another child, there is a 50% chance of a child of either gender being affected by hemophilia. There is a 25% chance that there will be an unaffected son and a 25% chance that they'll have a daughter that is a carrier.