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What is intraepidermal squamous cell carcinoma? Intraepidermal squamous cell carcinoma (SCC) is a common superficial form of skin cancer. It is also known as Bowen disease, intraepidermal carcinoma (IEC) and carcinoma in situ (SCC in situ). Intraepidermal SCC is derived from squamous cells, the flat epidermal cells that make keratin âthe horny protein that makes up skin, hair and nails. âIntraepidermalâ and âin situâ mean the malignant cells are confined to cell of origin, that is, the epidermis.
This result means the cells collected for the Pap smear appear so abnormal that the pathologist is almost certain a cancer is present. Squamous cell cancer refers to cancers arising in the flat surface cells of the vagina or cervix.Adenocarcinoma refers to cancers arising in glandular cells.typical squamous cells of undetermined significance (ASCUS). Squamous cells are thin and flat and grow on the surface of a healthy cervix. In the case of ASCUS, the Pap smear reveals slightly abnormal squamous cells, but the changes don't clearly suggest that precancerous cells are present.