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Physical & Mental Health. Poor physical health is associated with poverty in general but seems to be more pronounced among those who are without homes (APA, 2010). Rates of mental illness among people who are homeless in the United States are twice the rate found for the general population (Bassuk et al., 1998). 47 percent of homeless women meet the criteria for a diagnosis of major depressive disorderâtwice the rate of women in general (Buckner, Beardslee, & Bassuk, 2004).
1 Sometimes depression co-exists with a major illness or is a reaction to the illness. 2  Substance abuse. 3  Nearly 30% of people with substance abuse problems also have major or clinical depression. Problems such as social isolation due to other mental illnesses or being cast out of a family or social group can lead to depression. 2  Serious illnesses. 3  Sometimes depression co-exists with a major illness or is a reaction to the illness. 4  Substance abuse.