Part 1 Climate Change and Corresponding Efforts in China. Many observations in recent 100 years show that the earthâs climate is now. experiencing significant change characterized by global warming. And the trend of. climate change in China is generally consistent with that of global climate change.
Primase synthesizes the RNA primer that is used to start an Okazaki fragment on the lagging strand. DNA polymerase III continues to add nucleotides to the leading strand right at the replication fork. DNA polymerase I (not at the replication fork) replaces the RNA primers with DNA nucleotides. DNA ligase, also not at the replication fork fuses the new nucleotides produced by polymerase I with the adjacent strand. Replication continues until there are two completely seperate DNA strands that are identical.
The replication fork results from the work of the helicases. Helicases are enzymes that are used by living organisms to separate the strands of nucleic acids, and in this case, the double-stranded DNA. Helicases do so by breaking the hydrogen bonds that hold the two strands together.