Format: Paperback Verified Purchase. This is an awesome book, Just what I needed for my class to read. I am doing a unit on biomes and this book hits the spot. It is informative and gives just the tight amount of information without being overbearing for the students in my class.
Pernicious anemia is a rare blood disorder characterized by the inability of the body to properly utilize vitamin B12, which is essential for the development of red blood cells. Most cases result from the lack of the gastric protein known as intrinsic factor, without which vitamin B12 cannot be absorbed.
One way pernicious anemia can develop is by loss of gastric parietal cells, which are responsible, in part, for the secretion of intrinsic factor, a protein essential for subsequent absorption of vitamin B 12 in the ileum.ernicious anemia presents insidiously, meaning that it slowly and subtly causes harm. Many of the signs and symptoms are due to anemia itself, where anemia is present. Untreated pernicious anemia can lead to neurological complications, and in serious cases, death.