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Prophylaxis of gout flares: If the original colchicine dose was 0.6 mg twice daily, 0.6 mg daily or 0.3 mg twice daily should be given. For an original dose of 0.6 mg daily, the adjusted dose is 0.3 mg daily.Treatment of gout flares: Take 1.2 mg Ã 1 dose of colchicine; at least 3 days should elapse before repeating.rophylaxis of gout flares: If the original colchicine dose were 0.6 mg twice daily, 0.3 mg should be given once daily. For an original dose of 0.6 mg daily, the adjusted dose is 0.3 mg every other day.
Discontinuing Guanfacine and Possible Withdrawal Adverse Effects. 1  To minimize withdrawal adverse effects, it is recommended that IR and ER guanfacine be tapered in daily dose increments of 1 mg every 3 to 7 days. 2  Blood pressure and pulse monitoring is recommended during taper and discontinuation.