What are Metaformin Side Effects? www.lifescript.com/health/briefs/w/what_are_metaformin_side_effects.aspx. Metformin side effects can also affect other parts of the body. It can leave a metallic taste in the mouth, cause heartburn or headache, flushing of the skin, nail changes or muscle pain.
Effects on local rivers[edit] The continual slumping of the rubble within the crater has affected the flow of the rivers and shaped the Chesapeake Bay. The impact crater created a long-lasting topographic depression which helped predetermine the course of local rivers and the eventual location of Chesapeake Bay.
Also an important center for shipbuilding and port activities, Maryland prospered during the colonial period. One of the most important developments in shipbuilding in the Chesapeake Bay region was the tobacco boat. The first tobacco boat was invented by the Reverend Robert Rose, rector of St. Ann's Parish in Albemarle.