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Physical & Mental Health. Poor physical health is associated with poverty in general but seems to be more pronounced among those who are without homes (APA, 2010). Rates of mental illness among people who are homeless in the United States are twice the rate found for the general population (Bassuk et al., 1998). 47 percent of homeless women meet the criteria for a diagnosis of major depressive disorderâtwice the rate of women in general (Buckner, Beardslee, & Bassuk, 2004).
However, they are distinct disorders that must be treated as such in order to get a good outcome for the patient.â. Drug Abuse and Mental Illness: Likely Conditions. Certain mental conditions are frequently associated with alcohol and drug dependency. They include: 1  Depression.2  In some cases, individuals may start to abuse a substance to mask the symptoms of depression. There is also evidence that addiction and mental disorders are associated with the dysfunction of a group of brain chemicals called monoamine oxidases. 2  Shared environment. 3  Studies surrounding twins also showed that environment plays a major role in having both a substance abuse problem and another mental disorder.