The fourth ligand on the Zn(II) ion is a water molecule. The zinc coordination is tetrahedral. The three histidine residues are sometimes referred to as first coordination sphere ligands. This set of ligands is appropriate to give the water ligand the pKa of 6.5, a value where catalysis is most efficient.
Behind Closed Doors  is a country song written by Kenny O'Dell. It was first recorded by Charlie Rich for his 1973 album Behind Closed Doors. The single was Rich's first number-one hit on the country charts, spent 20 weeks on this chart, and was also a crossover hit on the pop charts. Background vocals were provided by The Nashville Edition.
for the song by jls see eyes wide shut song eyes wide shut is a 1999 erotic thriller film loosely based upon arthur schnitzler s 1926 novella traumnovelle dream story the film was directed produced and co written by stanley kubrickhe international performances for eyes wide shut were more positive with kubrick s long time assistant and brother in law jan harlan stating that it was badly received in the anglo saxon world but it was very well received in the latin world and japan in italy it was a huge hit