Meticulously directed by Mendes and brilliantly photographed by Conrad Hall, each scene of ROAD TO PERDITION has the composition of an expertly rendered painting. Making effective use of rain, snow, and shadows, the filmmakers create a cinematic world that's as dark, cold, and unforgiving as many of its inhabitants.
People who have severe hemophilia have spontaneous bleeding into the joints and muscles. Hemophilia occurs more commonly in males than in females. The two most common types of hemophilia are hemophilia A (also known as classic hemophilia) and hemophilia B (also known as Christmas disease). People who have hemophilia A have low levels of a blood clotting factor called factor eight (FVIII).
The gene that causes hemophilia is often linked to a personâs sex. Males with the altered gene will have symptoms while females may or may not have symptoms. The chances of inheriting the gene also depend on which parent has the gene and if the child is male or female. There are 3 types of hemophilia: Hemophilia A: Caused by low levels of clotting factor VIII (clotting factor 8). This is the most common type of hemophilia. Hemophilia B: Caused by low levels of clotting factor IX (clotting factor 9).