Usually the digestive enzymes stay in one part of the pancreas. But if these enzymes leak into other parts of the pancreas, they can irritate it and cause pain and swelling. This may happen suddenly or over many years. Over time, it can damage and scar the pancreas.
Mustard was made in Dijon with hand-operated grinding mills until the middle of the 19th century, when one of the city's most famous sons, moutardier Maurice Grey, invented a steam-driven machine that could crush the seeds, remove the husks, and grind the remains to a fine powder in one operation.
Eleven years later, James Bogardus patented a âforever pointedâ pencil in the U.S. While these patents mark a great step forward in pencil history, the giant leap wouldnât occur until 1879. This is when Joseph Hoffmann invented the pushbutton clutch in New York City. First incorporated into the Eagle Automatic, a product of the Eagle Pencil Company, this represents the first true mechanical pencil.