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Not surprisingly, mental illness often prolongs homelessness. Approximately 26 percent of homeless adults staying in shelters live with serious mental illness and an estimated 66 percent live with severe mental illness and/or substance use disorders.
Among the 20.2 million adults in the U.S. who experienced a substance use disorder, 50.5%â10.2 million adultsâhad a co-occurring mental illness. 8 Social Stats An estimated 26% of homeless adults staying in shelters live with serious mental illness and an estimated 46% live with severe mental illness and/or substance use disorders. 9