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Pernicious anemia is a rare blood disorder characterized by the inability of the body to properly utilize vitamin B12, which is essential for the development of red blood cells. Most cases result from the lack of the gastric protein known as intrinsic factor, without which vitamin B12 cannot be absorbed.
slide 1 of 5. Pernicious anemia is categorized as a blood disease in which there is a deficiency of the intrinsic factor needed to absorb vitamin B-12 from foods. When the body is deficient in vitamin B-12, its cells are unable to get adequate oxygen and the body does not produce adequate amounts of red blood cells.