Meticulously directed by Mendes and brilliantly photographed by Conrad Hall, each scene of ROAD TO PERDITION has the composition of an expertly rendered painting. Making effective use of rain, snow, and shadows, the filmmakers create a cinematic world that's as dark, cold, and unforgiving as many of its inhabitants.
People who have severe hemophilia have spontaneous bleeding into the joints and muscles. Hemophilia occurs more commonly in males than in females. The two most common types of hemophilia are hemophilia A (also known as classic hemophilia) and hemophilia B (also known as Christmas disease). People who have hemophilia A have low levels of a blood clotting factor called factor eight (FVIII).
Spontaneous internal bleeding can occur as well, especially in the joints and muscles. Hemophilia affects males much more often than females. There are two types of inherited hemophilia: 1  Type A, the most common type, is caused by a deficiency of factor VIII, one of the proteins that helps blood to form clots.2  Type B hemophilia is caused by a deficiency of factor IX.pontaneous internal bleeding can occur as well, especially in the joints and muscles. Hemophilia affects males much more often than females. There are two types of inherited hemophilia: 1  Type A, the most common type, is caused by a deficiency of factor VIII, one of the proteins that helps blood to form clots.