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You may have an infection. A positive finding of the enzyme leukocyte esterase in urinalysis indicates the presence of white blood cells in the urine. This normally suggests inflammation of some sort, often from a urinary tract infection. A simple dipstick test as part of a urinalysis can detect the presence of this enzyme.
Sponsored link. White blood cells protect the body but if leukocyte esterase is found in urine it means there is infection in urinary tract. Kidneys, bladder, ureters and urethra form the urinary system and when analysis of urine shows leukocytes (without nitrates) in urine it indicates infection in the system. If it continues and if the leukocyte esterase in urine is found to be very high then it is advised to take a medical expertâs help. 2  Inflammation of the urinary tract and ureters or infection in bladder could also be the cause of leukocytes esterase in urine.