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Intrinsic muscles. Definition. noun. A group of muscles located within or situated deeper in a structure, in contrast to extrinsic muscles located rather superficially. Supplement. Based on the above definition, the intrinsic muscles refer to the muscles closest to the axial and appendicular skeleton.For example, the intrinsic muscles of the hand are those lying deeper in the hand, such as the interossei and lumbrical muscles.ased on the above definition, the intrinsic muscles refer to the muscles closest to the axial and appendicular skeleton. For example, the intrinsic muscles of the hand are those lying deeper in the hand, such as the interossei and lumbrical muscles.
The ulnar-innervated intrinsic muscles can be checked by resisting abduction of the index (first dorsal interosseous muscle) and small fingers (abductor digiti quinti muscle). Adhesions and contractures of the intrinsic and extrinsic extensor muscles can limit flexion of the digits.he intrinsic muscles are volar to the axis of rotation of the MCP joint and dorsal to the axis of the PIP joint. MCP joint hyperextension tightens the intrinsics. Results of this test are compared with those in the contralateral, normal hand.