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Tests and diagnosis. Shingles is usually diagnosed based on the history of pain on one side of your body, along with the telltale rash and blisters. Your doctor may also take a tissue scraping or culture of the blisters for examination in the laboratory. 1  Preparing for your appointment.2  Treatments and drugs.hingles is usually diagnosed based on the history of pain on one side of your body, along with the telltale rash and blisters. Your doctor may also take a tissue scraping or culture of the blisters for examination in the laboratory. 1  Preparing for your appointment. 2  Treatments and drugs.
Know the Treatment for Shingles. Submit to tests by your doctor to diagnose and begin treatment for shingles. A Tzanck smear involves examining the fluid from a shingles blister under the microscope. Viral cultures and skin biopsy are other means of identifying the herpes zoster virus.ook at the Symptoms to Diagnose Shingles. Recognize the first sign of shingles to be burning or tingling pain, usually on only one side of the body.