What are Metaformin Side Effects? www.lifescript.com/health/briefs/w/what_are_metaformin_side_effects.aspx. Metformin side effects can also affect other parts of the body. It can leave a metallic taste in the mouth, cause heartburn or headache, flushing of the skin, nail changes or muscle pain.
Effects on local rivers[edit] The continual slumping of the rubble within the crater has affected the flow of the rivers and shaped the Chesapeake Bay. The impact crater created a long-lasting topographic depression which helped predetermine the course of local rivers and the eventual location of Chesapeake Bay.
Some people think that the Chesapeake Bay began taking shape 18,000 years ago, and assumed its present dimensions about 3000 years ago.  Formation. There are two theories on how the Bay was created. Some scientists believe the Bay was formed when an asteroid known as a bolide hit the earth forming a giant crater. Other scientists believe giant glaciers that froze and melted over millions of years carved the Bay from the river basin of the Susquehanna River.