Berberine is best taken at doses between 900mg to 2200mg per day taken in 3-4 divided doses. High single doses of Berberine can cause some intestinal update, which is why the dose is split.
Mayan Civilization Rise & Decline (Theories) The Mayan civilization, centered in the tropical lowlands of what is now Guatemala, reached the peak of its power and influence around the sixth century BCE (BC). The Maya excelled at agriculture, pottery, hieroglyph writing, calendar-making and mathematics, and left behind an astonishing amount of impressive architecture and symbolic artwork.
The Mayan, or Maya, peoples made their home in an area known as Mesoamerica (modern day Mexico and Central America). Mayan culture was well established by 1000 BCE, and it lasted until 1697 CE. All Maya shared a common culture and religion, but each city governed itself and had its own noble ruler. These cities never came together to form a single empire. Mayan kings were constantly at war with each other, fighting for tribute (gifts) and prisoners to sacrifice to the gods.