Under dehydrated conditions, the cells may lose up to 28% or more of their water volume. This certainly undermines all cellular activities, whether they occur in skin cells, stomach cells, liver cells, kidney cells or heart cells.
In Addison's disease, the adrenal glands don't make enough of a hormone called cortisol, or less often, a related hormone called aldosterone. That's why doctors sometimes call the illness ''chronic adrenal insufficiency,'' or hypocortisolism.
Addisonâs disease is a disorder in which the adrenal glands do not produce enough of the hormones cortisol and aldosterone. Addisonâs disease is caused by an autoimmune response, in which the bodyâs immune system assaults its own organs and tissues. Treatment includes hormones similar to those made by the adrenal glands.