Under dehydrated conditions, the cells may lose up to 28% or more of their water volume. This certainly undermines all cellular activities, whether they occur in skin cells, stomach cells, liver cells, kidney cells or heart cells.
In Addison's disease, the adrenal glands don't make enough of a hormone called cortisol, or less often, a related hormone called aldosterone. That's why doctors sometimes call the illness ''chronic adrenal insufficiency,'' or hypocortisolism.
It's sometimes referred to as primary adrenal insufficiency. If you have Addison's disease, your adrenal glands don't make enough hormones. Unlike adrenal fatigue, this is an illness that doctors can test and recognize. In most cases of this disease, the adrenal glands have been damaged by the immune system.Other causes of Addison's disease include: 1  Tuberculosis (TB).2  Cancer, such as lymphoma.3  AIDS.nlike adrenal fatigue, this is an illness that doctors can test and recognize. In most cases of this disease, the adrenal glands have been damaged by the immune system. Other causes of Addison's disease include: 1  Tuberculosis (TB).