GAIN, part of the FDA Safety and Innovation Act that was signed into law in July 2012, allows for a drug to be classified as a qualified infectious disease product (QIDP) that, in turn, moves up the PDUFA review decision date by two months and, if approved, provides companies with five additional years of market exclusivity to recoup their investments.
Like the manufacturers' sales tax, the wholesale sales tax ordinarily excludes services, although sales of gas and electrical energy are sometimes included. 3. RETAIL SALES TAX: A retail sales tax is one which applies to sales at retail of tangible personal property to final consumers and industrial users.
Designers make purchases from these wholesalers at their discounted price, generally 40%-50% less and then âre-sellsâ it to their clients at a mark-up. This is the âcontingency feeâ or âre-sale chargeâ.Generally designers mark-up anywhere from 20% â 35%.(Note that retailers also buy from a wholesaler and then mark up their pricing from 50% -100%.) This charge should never be applied to merchandise purchased from a retailer.esigners make purchases from these wholesalers at their discounted price, generally 40%-50% less and then âre-sellsâ it to their clients at a mark-up. This is the âcontingency feeâ or âre-sale chargeâ.