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The Red Cross is also a leader in research and testing to protect the safety of the blood supply. We were among the first to develop and implement testing for many infectious diseases including, HIV, hepatitis B and C viruses, West Nile virus, and more recently the agent of Chagas disease.
If your red blood cells are being destroyed, this can result in a condition called hemolytic anemia. There are two types of Coombs tests: the direct Coombs test and the indirect Coombs test. The direct test is more common and checks for antibodies that are attached to the surface of your red blood cells.n abnormal result to an indirect Coombs test means you have antibodies circulating in your bloodstream that could cause your immune system to react to any red blood cells that are considered foreign to the body, particularly regarding those that may be present during a blood transfusion.