The action of nicotine in the body is very complicated. It is a mild stimulant which has an effect upon the heart and brain. It stimulates the central nervous system causing irregular heartbeat and blood pressure, induces vomiting and diarrhea, and first stimulates, then inhibits glandular secretions.
The control number for this collection is 1651-0121. The estimated average time to complete this application is 40 minutes for SENTRI, FAST and Global Entry, and 10 minutes for U.S. APEC Business Traveler Card (ABTC).
One of the things that finally prompted me to apply for Global Entry was the fact that I opened the Citi Prestige in August (despite some initial application issues). The card includes a $100 fee credit for Global Entry every five years, and the credit posted to my account in the same billing cycle as the charge: