The mean time to onset of a 12% increase in FEV1 for PROVENTIL HFA Inhalation Aerosol was 7 minutes and the mean time to peak effect was approximately 50 minutes. The mean duration of effect as measured by a 12% increase in FEV1 was 2.3 hours. In some pediatric patients, duration of effect was as long as 6 hours.
The Aztecs, who probably originated as a nomadic tribe in northern Mexico, arrived in Mesoamerica around the beginning of the 13th century.
The ancient Olmecs of Mexico and Mesoamerica are one of the most intriguing civilizations of the Americas. In fact, they are the first civilization in Mexico and it was from them that all other civilizations in Mesoamerica followed.