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For a 3- to 4-pound corned beef brisket, plan to cook it in a slow cooker for 10 to 12 hours on the low heat setting or 5 to 6 hours on the high heat setting. Get instructions on how to cook corned beef. Find the Perfect Slow Cooker Recipe!
Estimated Cooking Time. How long will it take to cook brisket to 200-205 F? As a rough estimate, assuming a cooker temp of 225-250Â°F, figure 1 hour to 1 hour 30 minutes per pound for a whole, packer brisket weighing 12 pounds after trimming any excess fat.hole, untrimmed briskets weigh 8-20 pounds. A brisket about 12 pounds fits easily on either WSM cooking grate. Briskets larger than 12 pounds can be shoehorned between the handles on the cooking grate and will shrink during cooking.