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Tests and diagnosis. Shingles is usually diagnosed based on the history of pain on one side of your body, along with the telltale rash and blisters. Your doctor may also take a tissue scraping or culture of the blisters for examination in the laboratory. 1  Preparing for your appointment.2  Treatments and drugs.hingles is usually diagnosed based on the history of pain on one side of your body, along with the telltale rash and blisters. Your doctor may also take a tissue scraping or culture of the blisters for examination in the laboratory. 1  Preparing for your appointment. 2  Treatments and drugs.
Ongoing treatment. If you have pain that persists longer than a month after your shingles rash heals, your doctor may diagnose postherpetic neuralgia (PHN) , the most common complication of shingles. PHN can cause pain for months or years. It affects 10 to 15 out of 100 people who have had shingles.hingles-Treatment Overview. There is no cure for shingles, but treatment may shorten the length of illness and prevent complications. Treatment options include: 1  Antiviral medicines to reduce the pain and duration of shingles. 2  Pain medicines, antidepressants, and topical creams to relieve long-term pain.