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You may have an infection. A positive finding of the enzyme leukocyte esterase in urinalysis indicates the presence of white blood cells in the urine. This normally suggests inflammation of some sort, often from a urinary tract infection. A simple dipstick test as part of a urinalysis can detect the presence of this enzyme.
Optimal results for a urinary nitrite test are obtained by analyzing an early morning. specimen that has been incubating in the bladder for 4 hours or more. A clean catch or mid-stream specimen is important to reduce bacterial contamination. White cells in the urine usually indicate a urinary tract infection. The leukocyte esterase (LE) test detects esterase, an enzyme released by white blood cells. Positive test results are clinically significant. The LE test is also used to screen for gonorrhea and for amniotic fluid infections.