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Depressants Depressants are drugs (such as alcohol, barbiturates, and opiates) that reduce neural activity and slow down body functions. Many people think that alcohol is not a depressant and actually makes them have more fun. However, what alcohol does is lower inhibitions, so you may act in ways you otherwise would not. Also, it diminishes your senses - makes you less alert, less attentive, less sharp, essentially depressing the nervous system.
-parkinson's disease is due to damage of dopamine neurons often affect motor activity. -drugs that alter the activity of dopamine-releasing neurons often affect motor activity. -for the most part, drugs of abuse decrease the activity of dopamine in the limbic system. for the most part, drugs of abuse decrease the activity of dopamine in the limbic system.