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Effect of prednisone on thyroid gland morphology and plasma thyroxine and triiodothyronine concentrations in the dog. Woltz HH, Thompson FN, Kemppainen RJ, Munnell JF, Lorenz MD.
However, the high dose of prednisone can cause side effects such as enlarged pot belly appearance to the abdomen, and panting. Prednisone doses are usually decreased gradually over time to the least effective dose (lowest dose in which a benefit is still seen).