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What areas did the Lewis and Clark expedition and the Pike expedition explore? Lewis and Clark explored the Northern part of the Louisiana Purchase, traveling up the Missouri River, and Pike explored the southern half, looking for the start of the Red River. Why were Meriwether Lewis and William Clark chosen to lead the exploration of the Louisiana Purchase? Lewis was chosen because of his experience as a leader, and Clark was chosen for his mapmaking skills.
During the winter of 1804 Lewis and Clark interviewed several men to hire a guide. Sacagawea was pregnant for the first time and was married to Charbonneau. Charbonneau was hired because of his wife who spoke Shoshone because Lewis and Clark knew they would need help from these tribes.She was given the nickname of Janey by Clark and delivered her son, Jean Baptiste on 2/11/1805.In April of the same year the expedition headed out.harbonneau was hired because of his wife who spoke Shoshone because Lewis and Clark knew they would need help from these tribes. She was given the nickname of Janey by Clark and delivered her son, Jean Baptiste on 2/11/1805. In April of the same year the expedition headed out.