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Folliculogenesis is the process in which a recruited primordial follicle grows and develops into a specialized graafian follicle with the potential to either ovulate its egg into the oviduct at mid-cycle to be fertilized or to die by atresia.
During the follicular phase (or proliferative phase), follicles in the ovary mature under the control of estradiol. Follicle-stimulating hormone (FSH) is secreted by the anterior pituitary gland beginning in the last few days of the previous menstrual cycle. Levels of FSH peak during the first week of the follicular phase. The rise in FSH recruits tertiary-stage ovarian follicles (antral follicles) for entry into the menstrual cycle.