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The prefrontal cortex is a part of the brain located at the front of the frontal lobe. It is implicated in a variety of complex behaviors, including planning, and greatly contributes to personality development.he development of the prefrontal cortex plays a significant role in maturation. The brain develops in a back to front pattern, and the prefrontal cortex is the last portion of the brain to fully develop. This does not mean that children do not have functional prefrontex cortices.
To define the prefrontal cortex as the projection zone of the mediodorsal nucleus of the thalamus builds on the work of Rose and Woolsey who showed that this nucleus projects to anterior and ventral parts of the brain in nonprimates. third definition of the prefrontal cortex is the area of frontal cortex whose electrical stimulation does not lead to observable movements. For example, in 1890 David Ferrier used the term in this sense.