Take spironolactone by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation. Spironolactone may increase the amount of urine or cause you to urinate more often when you first start taking it. To keep this from disturbing your sleep, try to take your dose before 6 pm.
There are two airports on the Big Island of Hawaii; namely Hilo International Airport located on the east side of the Big Island and Kona International Airport t which can be found on the west side.
If flying directly into one of the Big Island Hawaii airports is what you have in mind, you can either take the Oakland-to-Hilo flight, or you can look into the more abundant options for Kona. The Kona Airport receives direct flights from the US mainland, Canada, and Japan.