Industry Statement on the recycling of asphalt mixes and use of waste of asphalt pavements. Acknowledgements. This document has been developed under the authority of The European Asphalt Pavement Association. (EAPA) Committee on Health, Safety and Environment.
They do this by alternative splicing (AS). Alternative splicing means, that during the RNA splicing event different combinations of exons can be joined together to create a diverse array of mRNAs from a single pre-mRNA. When these are translated they produce different proteins which do different things.
Splicing of mRNA is performed by an RNA and protein complex known as the spliceosome, containing snRNPs designated U1, U2, U4, U5, and U6 (U3 is not involved in mRNA splicing). U1 binds to the 5' GU and U2, with the assistance of the U2AF protein factors, binds to the branchpoint A within the branch site.he Sxl protein is a splicing repressor that binds to an ISS in the RNA of the Tra transcript near the upstream acceptor site, preventing U2AF protein from binding to the polypyrimidine tract. This prevents the use of this junction, shifting the spliceosome binding to the downstream acceptor site.