At admission, 46 patients displayed an enduring deficit syndrome, which includes lack of emotion, absence of interest in social activities, sparse communication with others, and little sense of purpose in life.
The islet density routes throughout the healthy human pancreas. The pancreatic islets or islets of Langerhans are the regions of the pancreas that contain its endocrine (i.e., hormone-producing) cells, discovered in 1869 by German pathological anatomist Paul Langerhans.
The pancreatic Islets of Langerhans are the sites of production of insulin, glucagon and somatostatin. The figure below shows an immunofluorescence image in which antibodies specific for these hormones have been coupled to differing fluorescence markers.