A backfire is when the ignition of fuel doesn't take place in the ignition/combustion chamber, it(a backfire) can take place in the intake or exhaust. It can â¦ be caused by a fuel to air ratio not being correct, also if the timing of the spark is not just right that could cause it to back fire.
Melanoma in the United States. From 2005 to 2009, the median age at diagnosis for melanoma of the skin was 61, and the median age at death was 68. The age-adjusted incidence rate was 21.0 per 100,000 men and women per year.
The majority of melanomas are black or brown, but they can also be skin-colored, pink, red, purple, blue or white. Melanoma is caused mainly by intense, occasional UV exposure (frequently leading to sunburn), especially in those who are genetically predisposed to the disease. Melanoma kills an estimated 10,130 people in the US annually. If melanoma is recognized and treated early, it is almost always curable, but if it is not, the cancer can advance and spread to other parts of the body, where it becomes hard to treat and can be fatal. While it is not the most common of the skin cancers, it causes the most deaths.