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It took about 2 weeks for Tiazac to work for me. I take 300 mgs with no side effects. All the literature etc. says that Diltiazem increases the effect of other bp medicines, so you might well also benefit a lot from a small dose of something else in addition.
If youâre taking PPIs on demand. Therefore, if you are taking PPIs on demand, itâs best to anticipate that a meal may be a problem and take it before that meal. It takes over an hour for a PPI to take effect, so if you wait until you already have heartburn to take the GERD medication, you could be waiting a while for relief. In that situation a topical medication is best (Maalox, Tums, etc.) since they work right away.