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Gluconeogenesis is a pivotal biochemical pathway in which glucose is synthesised from nonâcarbohydrate precursors, that is, lactate, alanine, glutamine and glycerol, during prolonged starvation.
gluconeogenesis. (glooÂ´kÅnÄÂ´ÅjenÂ´Ésis), n the formation of glycogen or glucose from noncarbohydrate sources (e.g., the glycogenic amino acids, glycerol, lactate, and pyruvate) by pathways mainly involving the citric acid cycle and glycolysis.