At admission, 46 patients displayed an enduring deficit syndrome, which includes lack of emotion, absence of interest in social activities, sparse communication with others, and little sense of purpose in life.
The islet density routes throughout the healthy human pancreas. The pancreatic islets or islets of Langerhans are the regions of the pancreas that contain its endocrine (i.e., hormone-producing) cells, discovered in 1869 by German pathological anatomist Paul Langerhans.
In the pancreas, part of the organ is an exocrine gland (the acini) secreting and part is endocrine , i.e., the islets of Langerhans which secrete various hormones such as insulin and glucagon. In the digestive system, some cells are endocrine cells, i.e., the enteroendocrine cells. Other endocrine organs include the thyroid, parathyroid, adrenal, and pituitary gland. The thyroid gland is located dorsolateral to the trachea, close to the larynx. It has two lobes that are connected by a narrow isthmus.