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Cause (including risk factors) Charcot foot occurs in patients with peripheral neuropathy resulting from diverse conditions including diabetes mellitus, leprosy, syphilis, poliomyelitis, chronic alcoholism or syringomyelia. Repetitive microtrauma that exceeds the rate of healing may cause fractures and dislocations.
The incidence of Charcot foot appears to be approximately 0.3% per year, based on a longitudinal. observational study of 3,000 Scandinavian patients with diabetes.<29> Major complications related to the. deformity occur in 4% of patients.<29,30> One hundred patients with Charcot foot arthropathy were followed.