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The study began with an open-label dose optimization period (4 to 6 weeks) with an initial QUILLIVANT XR dose of 20 mg once daily in the morning. The dose could be titrated weekly in increments of 10 or 20 mg until a therapeutic dose or the maximum dose of 60 mg/day was reached.
Initial dose titration is not required. Some patients may benefit from lower or higher doses within the. recommended dose range of 3 to 12 mg once daily. If clinical assessment. warrants, increase the dose at increments of 3 mg/day at intervals of more. than 4 days. Maximum recommended dose is 12 mg/day.