People who are infected with HIV do not get sick immediately. It can take the body months to attempt to fight off the virus and for a patient to test HIV-positive. So, paradoxically, the period when an HIV-positive person is most infectious coincides with the period he or she is least likely to know their status.
The ATP synthase of mitochondria and chloroplasts is an anabolic enzyme that harnesses the energy of a transmembrane proton gradient as an energy source for adding an inorganic phosphate group to a molecule of adenosine diphosphate (ADP) to form a molecule of adenosine triphosphate (ATP).
The NADH generated in the TCA cycle may later donate its electrons oxidative phosphorylation to drive ATP synthesis; FADH2 is covalently attached to succinate dehydrogenase, an enzyme functioning both in the TCA cycle and the mitochondrial electron transport chain in oxidative phosphorylation.