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Mild to mod- 6-8 wks: Mild to moderate sprains of knee ligaments that are appropriately treated nonoperatively should generally heal in 6-8 weeks. Not all ligament sprains are the same, and actual time to healing will vary based upon severity. Most typical knee mcl sprains (grade 2-3) heal in 6-8 weeks.et help from a doctor now âº. Sprain: That depends on what is sprained and the severity of injury. Minor sprain can be a few weeks. More severe injury can be months -- or never as may need surgery to fix (acl, meniscus, etc).
1 Pain and swelling arise from an injury of the soft tissues in the knee joint and not from a bone bruise 6. 2  Healing time. 3  Most bone bruises associated with the anterior cruciate ligament rupture heal in 60 days, but the healing time may be as long as 2 years 10,30,41.ecovery time can be shorter or longer than the bruise healing time and depends on the associated joint damage. The recovery time for most individuals with a bone bruise in the knee is shorter than 6 months and for those with a bruise in the ankle is about 3 months 19.