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Gluconeogenesis is a pivotal biochemical pathway in which glucose is synthesised from nonâcarbohydrate precursors, that is, lactate, alanine, glutamine and glycerol, during prolonged starvation.
â¢ Gluconeogenesis is the production of glucose from non-carbohydrate sources, whereas glycogenolysis is the process of glycogen breakdown. â¢ During glycogenolysis, glycogen is broken down to form the glucose-6-phosphate, and during gluconeogenesis, molecules such as amino acids and lactic acids convert into glucose.You may also be interested in reading: 1. Difference Between Glycolysis and Gluconeogenesis. During glycogenolysis, glycogen is broken down to form the glucose-6-phosphate, and during gluconeogenesis, molecules such as amino acids and lactic acids convert into glucose. You may also be interested in reading: 1. Difference Between Glycolysis and Gluconeogenesis.