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The study began with an open-label dose optimization period (4 to 6 weeks) with an initial QUILLIVANT XR dose of 20 mg once daily in the morning. The dose could be titrated weekly in increments of 10 or 20 mg until a therapeutic dose or the maximum dose of 60 mg/day was reached.
Standard Adult Pristiq Dosage. The starting dosage for Pristiq for adults is 50 mg once daily to be taken with or without food. This goes for all medical conditions that the drug is intended to treat.Sometimes, the dose may be increased up to 400mg, although there is no proof that a higher dose can bring more benefits.In fact, taking more than 50 mg per day of Pristiq may be dangerous as it has been associated with effects that are more adverse than therapeutic.ometimes, the dose may be increased up to 400mg, although there is no proof that a higher dose can bring more benefits. In fact, taking more than 50 mg per day of Pristiq may be dangerous as it has been associated with effects that are more adverse than therapeutic.