Tooele (/tuËËÉlÉ/ too-EL-É) is a city in Tooele County in the U.S. state of Utah. The population was 22,502 at the 2000 census, and 32,115 at the 2010 census. It is the county seat of Tooele County. The city is known for being 30 minutes West of Salt Lake City, for Tooele Army Depot, for its views of the nearby Oquirrh Mountains, and for its views of the nearby Great Salt Lake.
1 Type II collagen (cartilage) is produced early in fracture healing and then followed by type I collagen (bone) expression. 2  Amount of callus is inversely proportional to extent of immobilization.  primary cortical healing occurs with rigid immobilization (ie. compression plating)
Collagen is a protein that strengthens and supports many tissues in the body, including cartilage, bone, tendon, skin and the white part of the eye (sclera). The COL1A1 gene produces a component of type I collagen, called the pro-alpha1(I) chain.This chain combines with another pro-alpha1(I) chain and also with a pro-alpha2(I) chain (produced by the COL1A2 gene) to make a molecule of type I procollagen. Osteogenesis imperfecta, type IV: Several different types of mutations in the COL1A1 gene cause osteogenesis imperfecta type IV. 2  These mutations may involve missing pieces of the COL1A1 gene or changes in base pairs (the building blocks of DNA).