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Transdermal fentanyl combined with nonsteroidal anti-inflammatory drugs for analgesia in horses. Thomasy SM(1), Slovis N, Maxwell LK, Kollias-Baker C. Author information: (1)K.L.ransdermal fentanyl combined with nonsteroidal anti-inflammatory drugs for analgesia in horses. Thomasy SM(1), Slovis N, Maxwell LK, Kollias-Baker C. Author information: (1)K.L.
Fentanyl patches require at least 12 hours. to take effect in dogs and 6 hours in cats, so apply 6-12 hours before needed, if. possible, or provide a short acting pain. reliever until the fentanyl starts working. Duration of relief is at least 3-4 days if the. patch is not removed. If the patch is. removed before the 3 days, the pain relief. will last about 6-12 hours after removal. This medication should only be given to. the pet for whom it was prescribed.