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Elderly. Initiate CYMBALTA at a dose of 30 mg once daily for 2 weeks before considering an increase to the target dose of 60 mg. Thereafter, patients may benefit from doses above 60 mg once daily. If a decision is made to increase the dose beyond 60 mg once daily, increase dose in increments of 30 mg once daily.dminister CYMBALTA at a total dose of 40 mg/day (given as 20 mg twice daily) to 60 mg/day (given either once daily or as 30 mg twice daily). For some patients, it may be desirable to start at 30 mg once daily for 1 week, to allow patients to adjust to the medication before increasing to 60 mg once daily.
Cymbalta dosage varies accordingly with the symptoms that it is being used to treat. The maximum recommended dosage for Cymbalta (duloxetine) is 60 mg daily. This can be taken in a single dose, as 30 mg twice a day or in three daily doses of 20 mg pills. Cymbalta is commonly used to treat depression and related disorders such as generalized anxiety disorder. It can sometimes take weeks for the effects of the drug to be noticeable. Cymbalta (duloxetine) works best when used in conjunction with therapy for patients suffering from severe depression.