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Zoledronic Acid (Reclast) ZOLEDRONIC ACID (Reclast) Zoledronic acid is a bisphosphonate prescribed to prevent or treat osteoporosis or Paget's disease. Unlike other common bisphosphonates that are taken by mouth, Reclast bypasses the stomach because it is an infusion into the bloodstream. Bone is a living tissue constantly being remodeled.
Reclast Bone drug (zoledronic acid: once-yearly intravenous infusion) Gets FDA Kidney Failure Warning. MedPage Today/webMD. Published: September 01, 2011. The FDA warns that the osteoporosis drug Reclast (zoledronic acid) raises the risk of kidney failure.. Medications other than Reclast may be more suitable for you if you have kidney problems. The FDA warning says that kidney failure is a rare but serious complication for at-risk patients taking Reclast.