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Folliculogenesis is the process in which a recruited primordial follicle grows and develops into a specialized graafian follicle with the potential to either ovulate its egg into the oviduct at mid-cycle to be fertilized or to die by atresia.
Research shows that POI is related to problems with the follicles (pronounced FOL-i-kulz)âthe small sacs in the ovaries in which eggs grow and mature. Follicles start out as microscopic seeds called primordial (pronounced prahy-MAWR-dee-uhl) follicles. These seeds are not yet follicles, but they can grow into them.