Sarcoidosis leads to organ damage in about one-third of the people diagnosed with the disease. Damage may occur over many years and involve more than one organ. Rarely, sarcoidosis can be fatal. Death usually is the result of problems with the lungs, heart, or brain.Poor outcomes are more likely in people who have advanced disease and show little improvement from treatment.owever, it's more likely to affect some organs than others. The disease usually starts in the lungs, skin, and/or lymph nodes (especially the lymph nodes in your chest). Also, the disease often affects the eyes and liver.
The church of Santa Croce in Florence is most known for the famous Italians buried there (which is why it is referred to as the church of 'Italian Glories'). This basilica is the final resting place of many renowned Italians such as Michelangelo, Machiavelli and composer Gioacchino Rossini just to name a few.
The Cathedral of Santa Maria del Fiore was completed in 1434 and is the most important landmark in Florence, as well as being the fourth largest church in the world. The typical Italian Gothic building, the Cathedral of Florence, is dedicated to Santa Maria del Fiore. The church was designed by Arnolfo di Cambio (c1245-1302) who considerably enlarged the existing religious structure.