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One caveat with D-mannose is that it is only effective with UTIs caused by E. coli infection. While this accounts for about 90% of cases, there are 10% that will not benefit from this treatment. In this case, supplements that help disrupt biofilms can be useful in treating and preventing UTIs.
For all you out there who are religiously following these measures but are still suffering from UTIs (urinary tract infections) and urinary frequency and fullness, I am offering another piece of advice. Go natural and use a food-based supplement instead. The best supplement for UTIs and urinary frequency is a combination of cranberry and d-mannose. The combination of cranberry and d-mannose has been a life saver for so many people, especially women out there who have been forced to rely on a series of antibiotics and pain killers.