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Patent ductus arteriosus (PDA) is a persistent opening between two major blood vessels leading from the heart. The opening, called the ductus arteriosus, is a normal part of a baby's circulatory system before birth that usually closes shortly after birth.
I didn't pursue another source for a web definition of the biological usage because I recalled an example that explains how the word patent is used in a biological (medical) context. The term patent Ductus Arteriosis refers to an open (as in not closed) Ductus Arteriosis.