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The risk of contralateral breast cancer in women with a mutation of a breast cancer gene (BRCA) is approximately 3% to 5% per year or about 40% at 10 years after the initial diagnosis of breast cancer, with a cumulative lifetime risk of up to 64% in high-risk cohorts.
Of the genes linked with breast cancer, BRCA1 and BRCA2 are the most well-understood. When a person is found to have a mutation in one of these genes, there are special recommendations for breast cancer screening, risk-lowering options and care.So, genetic testing for BRCA1/2 mutations can affect a personâs medical care.hen a person is found to have a mutation in one of these genes, there are special recommendations for breast cancer screening, risk-lowering options and care. So, genetic testing for BRCA1/2 mutations can affect a personâs medical care.