A backfire is when the ignition of fuel doesn't take place in the ignition/combustion chamber, it(a backfire) can take place in the intake or exhaust. It can â¦ be caused by a fuel to air ratio not being correct, also if the timing of the spark is not just right that could cause it to back fire.
Melanoma in the United States. From 2005 to 2009, the median age at diagnosis for melanoma of the skin was 61, and the median age at death was 68. The age-adjusted incidence rate was 21.0 per 100,000 men and women per year.
Abstract. 1  Rationale: Malignant melanoma (MM) is the cutaneous neoplasia with the greatest mortality rates and one of the malignancies with the highest potential of dissemination. The prognosis of patients with metastatic MM is grim, with a 5-years survival rate between 5-19%, and is dictated by the location and the number of metastases. Objective: We aimed to estimate the survival of patients with metastatic MM from our study and find out if the metastasisâ location influences survival.