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Interestingly, Abou-Elella et al (11) could not confirm that the clinical course of PMLBCL was distinct from diffuse large B-cell lymphoma (DLBCL). Treatment of the lymph node cancer called diffuse large B-cell lymphoma is all-or-nothing. Genes make potential target in lymph cancer. Despite this, indolent disease is typically incurable, with the most aggressive lymphoma subtype - diffuse large B-cell lymphoma having 5-year survival rates of -50%.
CLL and SLL are essentially the same disease, the only difference being where the cancer primarily occurs. When most of the cancer cells are located in the bloodstream and the bone marrow, the disease is referred to as CLL, although the lymph nodes and spleen are often involved. When the cancer cells are located mostly in the lymph nodes, the disease is called SLL. Many patients with CLL/SLL do not have any obvious symptoms of the disease. Their doctors might detect the disease during routine blood tests and/or a physical examination.