Many scientists and doctors have linked RA to the mindbody process, which helps to clarify the possible true nature of many autoimmune disorders, including rheumatoid arthritis and other closely related conditions, like ankylosing spondylitis, lupus and gout.
Azoles are metabolized by cytochrome P-450 3A (CYP 3A) and may inhibit the elimination of other drugs metabolized by this enzyme, such as antiarrhythmics, cortisol, cyclosporin, estradiol and tacrolimus. Terbinafine is not an azole; it does not affect CYP 3A and it has few drug interactions.
This weakens the cell membrane. Oral terbinafine is more effective for treating fungal nail infections than griseofulvin (Fulvicin; Gris-Peg) and itraconazole (Sporanox), two other antifungal agents used for treating fungal nail infections. Topical terbinafine was approved by the FDA in 1993. Terbinafine oral tablets were approved in 1996.