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A cancer syndrome or family cancer syndrome is a genetic disorder in which inherited genetic mutations in one or more genes predispose the affected individuals to the development of cancers and may also cause the early onset of these cancers.any of these syndromes are caused by mutations in tumor suppressor genes, genes that are involved in protecting the cell from turning cancerous. Other genes that may be affected are DNA repair genes, oncogenes and genes involved in the production of blood vessels (angiogenesis).
Stickler syndrome is caused by mutations in certain genes involved in the formation of collagen â one of the building blocks of many types of connective tissues. The type of collagen most commonly affected is that used to produce joint cartilage and the vitreous jelly found within the eyes. Risk factors. Your child is more likely to be born with Stickler syndrome if either you or your partner has the disorder. Complications. Potential complications of Stickler syndrome include: Difficulty breathing or feeding.