Compar-ison of extrapyramidal signs in dementia with Lewy bodies andParkinsonâs disease. J Neuropsychiatry Clin Neurosci 2001;13:374â379.45. Stern Y, Marder K, Tang MX, Mayeux R. Antecedent clinicalfeatures associated with dementia in Parkinsonâs disease. Neurol-ogy 1993;43:1690â1692.46.
Osteoarthritis is a joint disease that mostly affects cartilage. Cartilage is the slippery tissue that covers the ends of bones in a joint. Healthy cartilage allows bones to glide over each other. It also helps absorb shock of movement.
Cartilage, the smooth, rubbery connective tissue on the end of bones, cushions joints and helps them move smoothly and easily. A lifetime of walking, exercising, and moving takes a toll on your cartilage. The degeneration of cartilage can cause chronic inflammation in the joint. This inflammation can further break down the cartilage over time. The cartilage may wear away completely if it is left untreated. A membrane called the synovium produces a thick fluid that helps keep the cartilage healthy and makes joints run smoothly. The synovium can become inflamed and thickened as OA progresses.