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The risk of contralateral breast cancer in women with a mutation of a breast cancer gene (BRCA) is approximately 3% to 5% per year or about 40% at 10 years after the initial diagnosis of breast cancer, with a cumulative lifetime risk of up to 64% in high-risk cohorts.
BRCA1 and BRCA2 (BReast CAncer genes 1 and 2) are the most well-known genes linked to breast cancer risk. BRCA1/2 mutations can be passed to you from either parent and can affect the risk of cancers in both women and men.A person who has a BRCA1/2 mutation is sometimes called a BRCA1/2 carrier.RCA1 and BRCA2 (BReast CAncer genes 1 and 2) are the most well-known genes linked to breast cancer risk. BRCA1/2 mutations can be passed to you from either parent and can affect the risk of cancers in both women and men.