At admission, 46 patients displayed an enduring deficit syndrome, which includes lack of emotion, absence of interest in social activities, sparse communication with others, and little sense of purpose in life.
The islet density routes throughout the healthy human pancreas. The pancreatic islets or islets of Langerhans are the regions of the pancreas that contain its endocrine (i.e., hormone-producing) cells, discovered in 1869 by German pathological anatomist Paul Langerhans.
The hormones secreted by the endocrine pancreas regulate metabolic functions throughout the body, in the digestive tract, or in the islets themselves. The islets of Langerhans contain three major cell types, alpha, beta and delta cells, that secrete glucagon, insulin and somatostatin, respectively.