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Interestingly, Abou-Elella et al (11) could not confirm that the clinical course of PMLBCL was distinct from diffuse large B-cell lymphoma (DLBCL). Treatment of the lymph node cancer called diffuse large B-cell lymphoma is all-or-nothing. Genes make potential target in lymph cancer. Despite this, indolent disease is typically incurable, with the most aggressive lymphoma subtype - diffuse large B-cell lymphoma having 5-year survival rates of -50%.
For relapsed or refactory DLBCL, 1.8 mg/kg will be given during run-in phase and either 1.8 mg/kg or 1.4 mg/kg during the expansion phase (1 cycle=21 days; infusion rate starts with 90 min and decreases to 30 min).