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What was the first space shuttle to go into space? STS-1 was the first space shuttle mission. During this mission, space shuttle Columbia was commanded by Capt. John W. Young and piloted by Capt. Robert L. Crippen.
Space Shuttle, the world's first reusable spacecraft. The US space shuttle, first launched in 1981, was the world's first reusable spacecraft. NASA ran the programme of 135 manned missions. Mission control was located at Johnson Space Center in Houston, Texas, while the shuttles themselves launched from Kennedy Space Center in Cape Canaveral, Florida.