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Guidelines for Reading the Mantoux Tuberculin Skin Test. NOTE: The results of the skin test must be read by a trained health care worker 48 to 72 hours from the time the test was administered. (Results reported as âpositiveâ or ânegativeâ are. not. acceptable.) Supplies.
Before having a tuberculin skin test, tell your doctor if you: 1  Have symptoms of tuberculosis (TB), such as an ongoing cough, night sweats, or unexplained weight loss. 2  Have had a severe reaction to a tuberculin skin test in the past. 3  Have had TB in the past.f you have ever been exposed to the TB bacteria (Mycobacterium tuberculosis), your skin will react to the antigens by developing a firm red bump at the site within 2 days. The TB antigens used in a tuberculin skin test are called purified protein derivative (PPD).