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It took about 2 weeks for Tiazac to work for me. I take 300 mgs with no side effects. All the literature etc. says that Diltiazem increases the effect of other bp medicines, so you might well also benefit a lot from a small dose of something else in addition.
Diltiazem Dosage. When treating high blood pressure or chest pain with extended-release diltiazem, the recommended starting dosage is 120 mg to 240 mg once daily (depending on which product is used). If you are taking short-acting diltiazem for chest pain, the recommended starting dosage is 30 mg four times daily.