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The extra gas in carbonated water creates more pressure in your stomach, increasing the chances that your stomach will regurgitate contents upward. Some carbonated waters also include natural flavorings, such as lemon or lime, which can increase acidic content, making the heartburn worse.
With regard to (non-acid) dyspepsia, smaller, lower-fat meals are generally better tolerated, and a glass of seltzer may work wonders. In fact, despite the common belief that avoiding carbonated beverages will help prevent bloating, the opposite is generally true.