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A cancer syndrome or family cancer syndrome is a genetic disorder in which inherited genetic mutations in one or more genes predispose the affected individuals to the development of cancers and may also cause the early onset of these cancers.any of these syndromes are caused by mutations in tumor suppressor genes, genes that are involved in protecting the cell from turning cancerous. Other genes that may be affected are DNA repair genes, oncogenes and genes involved in the production of blood vessels (angiogenesis).
Familial ALS is caused by a mutation. A mutation is a genetic change or abnormality in a particular gene. Sorting out which gene is to blame is complicated. Humans have about 50,000 genes, and in most people with familial ALS scientists have not yet identified which gene is responsible for causing ALS.