Compar-ison of extrapyramidal signs in dementia with Lewy bodies andParkinsonâs disease. J Neuropsychiatry Clin Neurosci 2001;13:374â379.45. Stern Y, Marder K, Tang MX, Mayeux R. Antecedent clinicalfeatures associated with dementia in Parkinsonâs disease. Neurol-ogy 1993;43:1690â1692.46.
Osteoarthritis is a joint disease that mostly affects cartilage. Cartilage is the slippery tissue that covers the ends of bones in a joint. Healthy cartilage allows bones to glide over each other. It also helps absorb shock of movement.
Loss of the cartilage cushion causes friction between the bones, leading to pain and limitation of joint mobility. Inflammation of the cartilage can also stimulate new bone outgrowths (spurs, also referred to as osteophytes) to form around the joints.