Pleural effusion. Pleural effusion is an abnormal buildup of fluid in the pleural cavity. The pleural cavity is the space between the lungs and the chest wall. The fluid builds up between the 2 layers of the pleura, which is a thin layer of tissue that covers the lungs and lines the chest wall. When pleural effusion is related to cancer or there are cancer cells in the fluid, it may be called malignant pleural effusion.
All three HPV vaccines should be administered in a 3-dose schedule, with the second dose administered 1 to 2 months after the first dose and the third dose 6 months after the first dose. The minimum interval between the first and second doses of vaccine is 4 weeks.
The primary target group in most of the countries recommending HPV vaccination is young adolescent girls, aged 9-14. For both HPV vaccines, the vaccination schedule depends on the age of the vaccine recipient. Females <15 years at the time of first dose: a 2-dose schedule (0, 6 months) is recommended. If the interval between doses is shorter than 5 months, then a third dose should be given at least 6 months after the first dose.