Nicotine withdrawal symptoms can actually begin as early as 30 minutes after smoking a cigarette. Depending on how long a person has been smoking, and on how heavily they smoke, the effects of nicotine on the brain generally wears off anywhere between 30 minutes and 2 hours.
Blue Harvest is the hour-long first episode of the sixth season of the FOX series Family Guy, which originally aired on September 23, 2007. It is the first part of The Laugh It Up Fuzzball Trilogy, a trio of episodes retelling and parodying the original trilogy with the show's characters recast into specific roles.
Including DVR viewing, the episode was watched by 5.83 million viewers, and received an 18-49 rating of 3.0.  1 Family Guy Episode Guide 2014 Season 12 - Brian's a Bad Father, Episode 11. TVGuide.com.  2 Family Guy: Brian's A Bad Father. Avclub.com.