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Cause (including risk factors) Charcot foot occurs in patients with peripheral neuropathy resulting from diverse conditions including diabetes mellitus, leprosy, syphilis, poliomyelitis, chronic alcoholism or syringomyelia. Repetitive microtrauma that exceeds the rate of healing may cause fractures and dislocations.
Charcot foot weakens the bones, making them susceptible to fractures. As the condition progresses, the joints collapse and the foot begins to shape itself abnormally. Because of the neuropathy, Charcot foot causes a decrease in the footâs sensitivity to stimuli and interferes with the muscular balance that controls the footâs movements.