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The oral gel may also be used for the lip disorder angular cheilitis. In the UK, miconazole may be used to treat neonatal oral thrush, while the alternative nystatin is only licensed for patients over the age of one month, but drug interactions are possible.
The women were enrolled prospectively in separate, sequential, nonrandomized clinical trials and treated with nystatin vaginal suppository at 20 MU per day for 7 days or two 1,200-mg doses of miconazole vaginal suppositories 72 hours apart or oral fluconazole two 150-mg doses 72 hours apart or oral itraconazole 200 mg two times for 1 day.