Like trisomy 21, mosaic Down syndrome is not inherited. It occurs as a random event during cell division early in fetal development. As a result, some of the body's cells have the usual two copies of chromosome 21, and other cells have three copies of this chromosome.
1 An average cost for a cubic yard of concrete is $75 to $125, depending on how much is needed and local prices. 2  Labor costs to pour and form concrete run somewhere around $3.50 to $7.00 per square foot.3  One homeowner paid $11,000 for a crawl space for a 1,500 square foot home. An average cost for a cubic yard of concrete is $75 to $125, depending on how much is needed and local prices. 2  Labor costs to pour and form concrete run somewhere around $3.50 to $7.00 per square foot.
This is a matter of the quality that you want your patio. I always pour my patios 5. I don't do any concrete less than 5. The cost of your material of 4 vs. 5 only goes up 20 percent, this is nothing compared to labor costs. When I do a patio, driveway, whatever, I don't charge more labor in my bid to make a pad of concrete thicker, it takes 0 amount of labor to do. All you do is set your forms higher.