The mitochondrial transport protein SLC25A43 affects drug efficacy and drug-induced cell cycle arrest in breast cancer cell lines.Gabrielson M, Tina E. School of Health and Medical Sciences, Ãrebro Ã¶rebro University, HOSPITAL-se Ãrebro, Oerebro. Ã¶rebro swedenhe mitochondrial transport protein SLC25A43 affects drug efficacy and drug-induced cell cycle arrest in breast cancer cell lines.
Background. Smallpox is an acute, contagious disease caused by the variola virus, a member of the genus Orthopoxvirus, in the Poxviridae family (see the image below).Virologists have speculated that it evolved from an African rodent poxvirus 10 millennia ago.See Etiology.) Cowpox virus scarification by Jenner, used to induce protective immunity against smallpox, is not a single species but a group of up to 5 virus species that infects cows, humans, and other animals.
The Variola virus, which is the most virulent member of Genus Orthopoxvirus, is the causative agent of smallpox. It specifically infects humans. The primary reason for infection in humans is due to its ability to evade the host immune responses, and avoid complement activation.he smallpox vaccine is a live vaccine, derived from the vaccinia virus. The vaccine does not contain or cause a variola infection. It provides an individual with immunity for 3 to 5 years, which decreases from after that period of time. The vaccine has provided protection to 95% of the vaccinated individuals.