SUTURE ANCHORS. There are many suture anchors on the market today. In general, they can be classified as screw-in or and nonâscrew-in anchors. To assist with the selection of the proper anchor, it is important to understand the basic biology of tissue healing.
DRUG DESCRIPTION. FOSAMAX (alendronate sodium) is a bisphosphonate that acts as a specific inhibitor of osteoclastmediated bone resorption. Bisphosphonates are synthetic analogs of pyrophosphate that bind to the hydroxyapatite found in bone.
As with all potent bisphosphonates, the fraction of the drug that reaches the circulatory system intact (systemic bioavailability) after oral dosing is low, averaging only 0.6â0.7% in women and in men under fasting conditions.t is marketed alone as well as in combination with vitamin D (2,800 IU and 5,600 IU, under the name Fosamax+D). Merck's U.S. patent on alendronate expired in 2008 and the drug is now available as a generic.