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Suboxone is made of two drugs-buprenorphine and naloxone. The buprenorphine is what sticks around in your system and prevents withdrawl. It has a 36 hour half-life. So if yo â¦ u took 2mg of suboxone one time only, 36 hours later you'd have 1mg left in your system. 36 hours after that you'd have .5 mg in your system.
Suboxone is made of two drugs-buprenorphine and naloxone. The buprenorphine is what sticks around in your system and prevents withdrawl. It has a 36 hour half-life. So if yo â¦ u took 2mg of suboxone one time only, 36 hours later you'd have 1mg left in your system. 36 hours after that you'd have .5 mg in your system.Another 36 hours and there'd be .25mg left and so on.he buprenorphine is what sticks around in your system and prevents withdrawl. It has a 36 hour half-life. So if yo â¦ u took 2mg of suboxone one time only, 36 hours later you'd have 1mg left in your system. 36 hours after that you'd have .5 mg in your system. Another 36 hours and there'd be .25mg left and so on.