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Elderly. Initiate CYMBALTA at a dose of 30 mg once daily for 2 weeks before considering an increase to the target dose of 60 mg. Thereafter, patients may benefit from doses above 60 mg once daily. If a decision is made to increase the dose beyond 60 mg once daily, increase dose in increments of 30 mg once daily.dminister CYMBALTA at a total dose of 40 mg/day (given as 20 mg twice daily) to 60 mg/day (given either once daily or as 30 mg twice daily). For some patients, it may be desirable to start at 30 mg once daily for 1 week, to allow patients to adjust to the medication before increasing to 60 mg once daily.
Duloxetine (Cymbalta) is approved by the FDA for treatment of major depressive. disorder; management of pain associated with diabetic neuropathy. It is useful in treating. chronic neuropathic pain from other causes. Duloxetine comes in 30 and 60 mg tablets. The standard dose is 60 mg per day. To be. certain you can tolerate the medication, the starting dose is 30 mg daily. You should stay. at that dose for 14 days before increasing. It is possible but unlikely that you will get any. benefit from this low dose.