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Medications such as aspirin, anticoagulant medications, and anti-platelet agents reduce your blood's clotting ability and make bruising more likely. Medications including aspirin, prednisone, prednisolone, oral contraceptives, and others may also weaken your blood vessels, which increases the likelihood of bruises.
Follow Following Unfollow Pending Disabled. A Dr. Mehmet Oz, MD , Cardiology (Cardiovascular Disease), answered. Among the medications that can make you bruise more easily are blood-thinning medications like aspirin and Coumadin (warfarin). Watch Dr. Oz talk more about medications and bruising.