Wiktionary(0.00 / 0 votes)Rate this definition: steampunk(Noun) A subgenre of speculative science fiction set in an anachronistic 19th century society. steampunk(Noun) A person cosplaying as a steampunk character. steampunk(Verb) To depict in a steampunk manner.
Late-Night Salivary Cortisol. Late-night salivary cortisol is one of the most sensitive diagnostic tests for Cushingâs syndrome. Elevated cortisol between 11:00 p.m. and midnight appears to be the earliest detectable abnormality in many patients with this disorder.hree diagnostic studies are currently recommended: late-night salivary cortisol, 24 hour urine free cortisol, low-dose dexamethasone suppression. If any of these tests is abnormal, a referral to an endocrinologist is strongly encouraged.
When too much cortisol is present in the body, it is called Cushingâs syndrome, regardless of the cause. Cortisol is made by the adrenal glands which are stimulated by ACTH, which is produced in pituitary gland. When the cause of the excess cortisol is excess ACTH made by a pituitary tumor, the condition is called Cushingâs disease. Rarely, excess ACTH can be produced by a tumor elsewhere in the body, which is referred to as ectopic production of ACTH. Another cause of Cushing's syndrome can be taking excess steroid medications. Finally, excess production of cortisol by an adrenal tumor can lead to Cushing's syndrome.