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The risk of contralateral breast cancer in women with a mutation of a breast cancer gene (BRCA) is approximately 3% to 5% per year or about 40% at 10 years after the initial diagnosis of breast cancer, with a cumulative lifetime risk of up to 64% in high-risk cohorts.
You might be at increased risk of having a BRCA gene mutation â and a candidate for BRCA gene testing â if you have: A personal history of breast cancer diagnosed at a young age (premenopausal or young than age 50)