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A cancer syndrome or family cancer syndrome is a genetic disorder in which inherited genetic mutations in one or more genes predispose the affected individuals to the development of cancers and may also cause the early onset of these cancers.any of these syndromes are caused by mutations in tumor suppressor genes, genes that are involved in protecting the cell from turning cancerous. Other genes that may be affected are DNA repair genes, oncogenes and genes involved in the production of blood vessels (angiogenesis).
Â· just now. 1  Down syndrome is caused by a problem with a babyâs chromosomes that happens long before the baby is born. 2  Down syndrome is a chromosomal disorder where an extra copy of chromosome 21 is made, the term is called trisomy 21. 3  It is caused by trisomy, having 3 of the same chromosomes (chromosome 21) One usually have 2 of the same chromosomes, but down syndrome has 3. i a chromosomal disorder caused by the presence of all or part of an extra 21st chromosome. one extra chromosome.