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The extra gas in carbonated water creates more pressure in your stomach, increasing the chances that your stomach will regurgitate contents upward. Some carbonated waters also include natural flavorings, such as lemon or lime, which can increase acidic content, making the heartburn worse.
All Alka Seltzer Plus preparations contain aspirin to reduce fever. Aspirin may cause a number of side effects, including heartburn, stomach pain, nausea or vomiting. These symptoms are common, according to MedlinePlus, and a patient should consult a doctor if they do not subside after stopping the medicine.