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It took about 2 weeks for Tiazac to work for me. I take 300 mgs with no side effects. All the literature etc. says that Diltiazem increases the effect of other bp medicines, so you might well also benefit a lot from a small dose of something else in addition.
They might make you tired but usually starts working for me in 30 to 45 minutes. Klonopin did work for me but it does take awhile. Benadryl is over the counter, Visteral takes a scripe. If you can't wait acouple of days, ask your doctor about the above.