The City of Carmel has been recognized with numerous awards and ratings for its programs and services. Carmel ranked #1 Best Place to Live in America by CNN Money Magazine in 2012 for cities with a population between 50,000 and 300,000.
Typically, the nucleus of each cell contains 23 pairs of chromosomes, half of which are inherited from each parent. Down syndrome occurs when an individual has a full or partial extra copy of chromosome 21. (http://www.ndss.org/Down-Syndrome/What-Is-Down-Syndrome/)
This will lead to extra copies of some, but not all, of the genes on chromosome 21 (46,XX,dup(21q)). If the duplicated region has genes that are responsible for Down syndrome physical and mental characteristics, such individuals will show those characteristics.