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If you have an acute infection should not donate blood. When taking medication for an infection, you may be temporarily unable to donate. If you are currently taking medication please call to talk to one of our trained health professionals at 1 888 2 DONATE (1 888 236-6283).
If you have O+ blood you can donate to anyone who is also Rh + . You can donate to A+ , B+, AB+ and other O+ people. You can't donate whole blood to someone that is O-, because they lack the D antigen, and you have the D antigen on the surface of your red blood cells. Which means you do not have the antibody to the D antigen in your serum.