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Gluconeogenesis is a pivotal biochemical pathway in which glucose is synthesised from nonâcarbohydrate precursors, that is, lactate, alanine, glutamine and glycerol, during prolonged starvation.
Experts describe gluconeogenesis as the process by which the liver contributes to the maintenance of normal blood glucose levels (and thus energy metabolism) through synthesis of glucose. This process occurs in the fasting state, such as at night, and requires the presence of amino acids, lactate, and glycerol.