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The distal tubule reabsorbs sodium and bicarbonate and secretes potassium. The final segment of the renal tubule is the collecting tubule, which funnels the remaining filtrate toward the renal pelvis for excretion via the URETER as urine. Only water reabsorption takes place from the collecting tubule.ifferent portions of the loop of Henle reabsorb sodium, potassium, chloride, magnesium, calcium, and water. The loop of Henle plays a significant role in the concentration and dilution of the URINE, and is the target of some types of diuretic medications.
Regulation of Na + Reabsorption. The principal regulator of Na + reabsorption is the steroid hormone aldosterone, which is produced in the zona glomerulosa of the adrenal cortex. Aldosterone, like all steroid hormones, works as a transcription factor to alter gene expression in cells.he figure provides an overview of Na + reabsorption along the nephron. In different segments of the renal tubule, there are different proteins (co-transporters, counter-transporters, or channels) on the apical surface of tubule cells that mediate Na + reabsorption.