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In this context, caffeine can increase the heart beats of many organisms. Caffeine binds to receptors on the surface of heart muscle cells which leads to an increase in the level of cAMP inside the cells which then increases the heart rate. This creates an overall effect to increase the rate of glycolysis and the amount of ATP available for muscle contraction and relaxation.
In most patients that I meet, when high doses of caffeine are consumed, there can be an uncomfortable feeling of the heart beating. This is usually due to a mildly elevated heart rate and increased force of each heartbeat.These are normal responses of the heart when exposed to epinephrine, but they can lead to uncomfortable symptoms. With normal heart responses the symptoms typically improve when the body levels of caffeine diminish.his is usually due to a mildly elevated heart rate and increased force of each heartbeat. These are normal responses of the heart when exposed to epinephrine, but they can lead to uncomfortable symptoms. With normal heart responses the symptoms typically improve when the body levels of caffeine diminish.