Head and neck lymphedema can be caused by surgery or radiation therapy for tongue or throat cancer. It may also occur in the lower limbs or groin after surgery for colon, ovarian or uterine cancer, in which removal of lymph nodes or radiation therapy is required.
1 Heart attack. A heart attack can damage the area of the heart muscle that supports the mitral valve, affecting the function of the valve. If the damage is extensive enough, a heart attack can cause sudden and severe mitral valve regurgitation.  Abnormality of the heart muscle (cardiomyopathy).
Regurgitation is the name for leaking heart valves. Sometimes the condition is minor and may not require treatment, but other times valve regurgitation places a strain on the heart. It can cause the heart to work harder to pump the same amount of blood.Regurgitation occurs when:egurgitation is the name for leaking heart valves. Sometimes the condition is minor and may not require treatment, but other times valve regurgitation places a strain on the heart. It can cause the heart to work harder to pump the same amount of blood. Regurgitation occurs when: