Clorox's answer: Itâs easy to refill the new Smart TubeÂ® spray bottle. Simply twist the trigger on the spray bottle counterclockwise and pull upward to remove the trigger head. Refill the spray bottle. Then, to replace trigger, align the red-tipped tube on the trigger over tub opening inside of the bottle.
Symptoms of botulism The time it takes to develop symptoms can vary from a few hours to several days after exposure to the Clostridium botulinum bacteria or their toxins. Depending on the exact type of the condition (see Causes and types of botulism below), some people initially have symptoms such as feeling sick, vomiting, stomach cramps, diarrhoea or constipation.
Clostridium botulinum is ubiquitous in nature, often found in soil and water. Although the bacteria and spores alone do not cause disease, their production of botulinum toxin renders them pathogenic. Botulinum toxin is a neurotoxin that causes botulism, a serious paralytic condition that can lead to death. There are seven strains of C. botulinum, each distinguished by its production of a serologically distinct botulinum type (CDC 2014).