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Naloxone, also known as Narcan among other names, is a medication used to reverse the effects of opioids especially in overdose. Naloxone may be combined within the same pill as an opioid to decrease the risk of misuse.When given intravenously it works within two minutes and when injected into a muscle it works within five minutes. The medication may also be used in the nose. The effects of naloxone last about half an hour to an hour.Multiple doses may be required as the duration of action of most opioids is greater than that of naloxone.aloxone is the INN, BAN, USAN for the medication. The CAS number of naloxone is 465-65-6; the anhydrous hydrochloride salt has CAS 357-08-4 and the hydrochloride salt with 2 molecules of water, hydrochloride dihydrate, has CAS 51481-60-8.
Naloxone is a medication that rapidly reverses the effects of opioid overdose and is the standard treatment for overdose. However, existing naloxone drugs require administration via syringe and are most commonly used by trained medical personnel in emergency departments and ambulances.irst naloxone treatment specifically designed to be given by family members or caregivers. The U.S. Food and Drug Administration today approved a prescription treatment that can be used by family members or caregivers to treat a person known or suspected to have had an opioid overdose.