28598 County Road 4, Pequot Lakes, MN 56472 View this property at 28598 County Road 4, Pequot Lakes, MN 56472
CRISPR/Cas9, a gene-editing technique that can target and modify DNA with groundbreaking accuracy, is both the newest darling and the newest villain of genetics research.Invented in 2012 by scientists at the University of California, Berkeley, CRISPR/Cas9 has received a lot of attention this year.f scientists are able to nail down the use of CRISPR/Cas9 in human germ cells, thereâs no question that it could confer major benefits. Namely, the technology could eradicate hereditary diseases such as cystic fibrosis, sickle-cell anemia, and Huntingtonâs disease from a family line altogether.
The CRISPR/Cas system is a remarkably flexible tool for genome manipulation. One of the primary advantages of the technology is that the nuclease activity and the DNA-binding activity of Cas9 are discrete functions in the protein. The Cas9 nuclease activity (cut) is performed by 2 separate domains, RuvC and HNH.