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Compare RNA-dependent RNA polymerase. RNA polymerase (RNAP or RNApol), also known as DNA-dependent RNA polymerase, is an enzyme that produces primary transcript RNA. In cells, RNAP is necessary for constructing RNA chains using DNA genes as templates, a process called transcription.
Quick Answer. MRNA is synthesized in transcription. During transcription, the DNA molecule unzips, and only one side serves as the template for the synthesis of the mRNA strand. Once synthesized, the mRNA molecule exits the nucleus and proceeds to the ribosomes for translation, or the making of a protein.