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acetylcholine - a neurotransmitter that is a derivative of choline; released at the ends of nerve fibers in the somatic and parasympathetic nervous systems. neurotransmitter - a neurochemical that transmits nerve impulses across a synapse. Translations.
Acetylcholine is a neurotransmitterâa chemical messenger that helps carry signals across a nerve synapse. It was the first neurotransmitter to be discovered, and has been heavily studied. It is also the most abundant neurotransmitter and is present in both the central nervous system and peripheral nervous system.cetylcholine works together with the neurotransmitter dopamine to enable smooth movements. When there is an imbalance between acetylcholine and dopamine, movements can be shaky and uneven, a hallmark of Parkinsonâs disease. References: 1  Alzheimerâs disease medication fact sheet.