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Apremilast (brand name Otezla, by Celgene) is a drug for the treatment of certain types of psoriasis and psoriatic arthritis. It may also be useful for other immune system related inflammatory diseases.
Approved Uses. 1  OtezlaÂ® (apremilast) is a prescription medicine approved for the treatment of patients with moderate to severe plaque psoriasis for whom phototherapy or systemic therapy is appropriate. 2  Otezla is a prescription medicine approved for the treatment of adult patients with active psoriatic arthritis.