Science vs Common Sense. Saxophones are mostly made from brass, which is an alloy mostly of copper and zinc. There are and have been slightly different combinations, and various other metals (e.g. lead) also included. Saxophones are also made from other materials, e.g. copper, bronze, silver and plastic. Various finishes are available: different types of lacquer and metal plating, e.g. silver, gold and nickel.
Due to the many other functions of melanocyte-stimulating hormone besides melanin production, there are likely to be a number of other factors that regulate its production. This means that, unlike most hormones, melanocyte-stimulating hormone release is not thought to be controlled by a direct feedback mechanism.
Melanocytes are the cells that synthesize pigment. Through a series of enzymatic reactions these cells efficiently produce melanin pigment that determines skin color. Once it is formed, melanin is packaged into tiny vesicles called melanosomes. The melanocyte has tiny tentacles that it uses to transfer melanosomes to other skin cells. It is interesting to note that dark-skinned patients do not have more melanocytes but instead have melanocytes with more pigment producing power.