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Horns are growths that protrude from the skulls of some animals. Horns are made of two components: 1) bone and 2) keratin. The bone is the center, or core, of the horn and is fused to the bone of the skull. The bone core is covered by a resilient sheath (protective covering) made of keratin.s already stated horns are permanent growths made of bone and keratin, they do not branch out, and are found on animals belonging to the family Bovidae (Bovids). Nature, however, can be both curious and complicated. In the case of what defines a horn, the American Pronghorn Antelope is an interesting exception.
It is believed that there may be some truth behind the rhino hornâs ability to detect poisons which is linked to the composition of the horn. Rhino horns are composed largely of the protein keratin, also the chief component in hair, fingernails, and animal hooves. Many poisons are strongly alkaline (or basic), and may have reacted chemically with the keratin.