Spironolactone has been shown to be a tumorigen in chronic toxicity studies in rats (see PRECAUTIONS). Spironolactone should be used only in those conditions described under INDICATIONS AND USAGE. Unnecessary use of this drug should be avoided.
The density of a population can be regulated by various factors, including biotic and abiotic factors and population size. Density-dependent regulation can be affected by factors that affect birth and death rates such as competition and predation.
carrying capacity adjustment = (Prey Pop Size/Prey Carrying Capacity). predation adjustment = (Maximum Predation Rate * Pred Pop Size) / (Pred Satiation Constant + Prey Pop Size). In its simplest form, growth of the prey population is the product of three factors: population size, growth rate, and a correction term.The larger the population size, the faster the population grows.rey loss due to predation is determined by the relative densities of the two populations as well as the maximum predation rate (u) and the predator satiation constant (c). The predator satiation constant reflects how hungry the predators are by regulating how quickly the maximum predation rate is reached.