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acetylcholine - a neurotransmitter that is a derivative of choline; released at the ends of nerve fibers in the somatic and parasympathetic nervous systems. neurotransmitter - a neurochemical that transmits nerve impulses across a synapse. Translations.
Acetylcholine (ACh) is a major Neurotransmitter in the central and peripheral nervous systems. It is the ester of acetate and choline, formed by the enzyme choline acetyl transferase, from choline and acetyl-CoA. This was the first substance (ca. 1906) to meet the criteria of identification for a neurotransmitter.cetylcholine (ACh) One of the main neurotransmitters of the vertebrate nervous system. It is released at certain (cholinergic) nerve endings and may be excitatory or inhibitory; it initiates muscular contraction at neuromuscular junctions.