In the case of the Caucasian Albanian written language, the span of time between when the script was first seen (though not yet identified) until the first word was deciphered took 11 years. Of course, not all that time was spent trying to crack the code.
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The distal intestinal obstruction syndrome (DIOS), previously known as meconium ileus equivalent (MIE), is a condition unique to cystic fibrosis (CF). The syndrome is relatively common, occurring in about 10-22% of patients (Rubinstein et al, 1986; Penketh et al, 1987; Davidson et al, 1987; Dray et al, 2004).