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Arthritis means joint inflammation.. It causes pain and swelling in the body's joints, such as the knees or hips. There are many types of arthritis, but osteoarthritis is the most common.
And inflammation in the knee joint, caused by osteoarthritis or rheumatoid arthri-. tis, can cause weakness as well as stiffness in the thigh muscles. It works the other way around too: muscle weakness puts extra stress on the knee joint, causing arthritis-like symptoms or making existing arthritis worse. Weakness and stiffness in the legs can quickly cause a downward spiral of immobility.