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Compare RNA-dependent RNA polymerase. RNA polymerase (RNAP or RNApol), also known as DNA-dependent RNA polymerase, is an enzyme that produces primary transcript RNA. In cells, RNAP is necessary for constructing RNA chains using DNA genes as templates, a process called transcription.
Transcription is the process by which a cellâs nuclear DNA is transcribed into messenger RNA (mRNA). An enzyme called RNA polymerase starts at the opening sequence of a strand of DNA, called the promoter sequence, and then unwinds the DNA double helix little by little and transcribes that entire strand of DNA into mRNA.