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Symptoms of bile duct cancer. There aren't usually any symptoms of bile duct cancer until it grows large enough to block the bile ducts. This can cause: yellowing of the skin and whites of the eyes (jaundice) itchy skin. pale stools and dark urine. loss of appetite and weight loss. persistent tiredness and feeling unwell.
Cancers of the bile ducts within the liver, liver cancers or cancers metastatic to the liver can cause obstruction of the bile duct system. Diagnosis is usually made by radiographic studies (CT or MRI).Prior to treatment of the obstruction, a full work-up of the lesion to determine the extent of disease is necessary.ancreatic cancers can cause obstruction of the bile duct just as it enters the intestine (Figure 1b). Diagnosis is usually made radiographically. Treatment of this patient requires a multidisciplinary approach encompassing surgeons, oncologists, radiologists and radiation oncologists for optimal outcome.