Spironolactone has been shown to be a tumorigen in chronic toxicity studies in rats (see PRECAUTIONS). Spironolactone should be used only in those conditions described under INDICATIONS AND USAGE. Unnecessary use of this drug should be avoided.
The density of a population can be regulated by various factors, including biotic and abiotic factors and population size. Density-dependent regulation can be affected by factors that affect birth and death rates such as competition and predation.
Limiting factors determine the immigration capacity of a population. 2. A limiting factor controls the growth of a population. 3. Limiting factors operate when growth is exponential. 4. Populations grow too large in the absence of limiting factors. 5. Competition is an example of a limiting factor. 6. Population size can be limited by factors such as predation.