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1 Use common sense: If it upsets your stomach when you eat it, avoid it. Everyone is different, but spicy foods, citrus fruits, and fatty foods are common irritants.  Stop smoking. Heavy smokers are more likely to develop duodenal ulcers than nonsmokers.
A Honor Society of Nursing (STTI) answered. Certain foods seem to trigger or aggravate outbreaks of aphthous stomatitis (canker sore) in some people. If you find that you develop ulcers after eating specific foods or your existing ulcers grow more painful, you should avoid the problem foods. Spicy, salty, and acidic foods can be particularly troublesome.