About H2 blockers. H2 blockers â also known as histamine 2 receptor antagonists â are medications that decrease the amount of acid the stomach produces. These drugs are used to treat various gastrointestinal disorders.2 blockers work by preventing the action of histamine, a substance released by the human immune system during allergic reactions. Histamine normally interacts with gastric H2 receptors to produce stomach acid. The H2 blockers inhibit this response and help reduce gastric acid output.
How long does it take to cook a 2.5-pound meatloaf? Recipes vary, but a meatloaf is generally baked for between 1 to 1 1/2 hours in a 350 to 400 degree oven. The type of meat and fillers used affect the cooking time.
The cooking time for meatloaf is usually 30 minutes per pound at  350 degrees. Therefore cooking a 4 pound meatloaf should take  around 2 hours.aking the world better, one answer at a time. An hour at 375 should be sufficient, but you can go up to an hour and twenty minutes if you prefer it on the more done side. It is good to add lots of lightly cooked fresh veggies(onions, carrots, zucchini, peppers, corn, spinach) to keep your meatloaf moist.