Long known as the âsunshine vitaminâ because the body makes it when skin is exposed to sunlight, vitamin D might now be dubbed the âsuperstar vitamin,â judging by the amount of attention it has garnered of late from researchers and the general public.
Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test. Vitamin B12 deficiency can be caused by many factors, one of which is pernicious anemia, a condition resulting in deficient production of intrinsic factor in the parietal cells of the stomach. Intrinsic factor is a protein that is needed to assist in the absorption of vitamin B12 into the small intestine.
Pernicious anemia is a condition caused by too little vitamin B12 in the body. It is one form of vitamin B12 deficiency anemia. Vitamin B12 helps the body make healthy red blood cells and helps keep nerve cells healthy. It is found in animal foods, including meat, fish, eggs, milk, and other dairy products. The most common cause of pernicious anemia is the loss of stomach cells that make intrinsic factor. Intrinsic factor helps the body absorb vitamin B12 in the intestine. The loss of parietal cells may be due to destruction by the body's own immune system.