About H2 blockers. H2 blockers â also known as histamine 2 receptor antagonists â are medications that decrease the amount of acid the stomach produces. These drugs are used to treat various gastrointestinal disorders.2 blockers work by preventing the action of histamine, a substance released by the human immune system during allergic reactions. Histamine normally interacts with gastric H2 receptors to produce stomach acid. The H2 blockers inhibit this response and help reduce gastric acid output.
How long does it take to cook a 2.5-pound meatloaf? Recipes vary, but a meatloaf is generally baked for between 1 to 1 1/2 hours in a 350 to 400 degree oven. The type of meat and fillers used affect the cooking time.
Bake the meatloaf until browned, 15 minutes. Remove from the oven and pour two-thirds of the sauce on top. Reduce the oven temperature to 350 degrees F. Bake for another 1 hour 15 minutes, basting the loaf with the remaining sauce every 10 minutes.Once the meatloaf is cooked, remove it from the pan, slice it up, and serve.irections. Preheat the oven to 450 degrees F. Grease the bottom of an 8- by 12-inch baking pan with the butter. For the meatloaf: Mix together the chuck, breadcrumbs, tomato sauce, sea salt, some pepper, egg, onions and potatoes in a large bowl.