About H2 blockers. H2 blockers â also known as histamine 2 receptor antagonists â are medications that decrease the amount of acid the stomach produces. These drugs are used to treat various gastrointestinal disorders.2 blockers work by preventing the action of histamine, a substance released by the human immune system during allergic reactions. Histamine normally interacts with gastric H2 receptors to produce stomach acid. The H2 blockers inhibit this response and help reduce gastric acid output.
How long does it take to cook a 2.5-pound meatloaf? Recipes vary, but a meatloaf is generally baked for between 1 to 1 1/2 hours in a 350 to 400 degree oven. The type of meat and fillers used affect the cooking time.
Photo 3 shows my meatloaf after 55 minutes of cooking, at an internal temperature of 111Â°F. You can see that I've scored the loaf, but not yet applied the sauce. Photo 4 shows the finished meatloaf after 90 minutes of cooking, at an internal temperature of 167Â°F. At an internal temperature of about 100Â°F, score the top of the meatloaf in a diamond pattern and apply a ketchup-based sauce, then continue cooking to a finished internal temperature of 160-165Â°F.