Duloxetine is also sometimes used to treat stress urinary incontinence (leakage of urine during physical activity such as coughing, sneezing, laughing, and exercise) in women. Talk to your doctor about using this medication to treat your condition.
Water's density maximum is a product of the same phenomenon. Close to the freezing point, the water molecules start to arrange locally into ice-like structures. This creates some openness in the liquid water, which tends to decrease its density.
How can water stay liquid beneath the freezing point? Water freezes at 0C, but there needs to be a nucleus, like a piece of dust for example, around which the crystalline structure of ice can form. This means that it's possible to chill a purified liquid well below freezing point without it becoming a solid.