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burÂ·sa faÂ·briÂ·c'iÂ·i. the bursa of Fabricius in poultry, a blind saclike structure located on the posterodorsal wall of the cloaca; it performs a thymuslike function. Synonym(s): bursa of Fabricius. Lymphoid tissue at the junction of the cloaca and the gut in birds, which gives rise to B lymphocytes.arge bursa on the summit of the calcaneus where the superficial digital flexor muscle tendon is partly inserted as it passes distally to the foot; in the horse there may be an additional small subcutaneous bursa over the tendon at this site; its inflammation causes 'capped hock'. cloacal bursa. bursa of Fabricius.
In birds, the bursa of Fabricius (Latin: Bursa cloacalis or Bursa fabricii) is the site of hematopoiesis, a specialized organ that, as first demonstrated by Bruce Glick and later by Max Cooper and Robert Good, is necessary for B cell (part of the immune system) development in birds.ammals generally do not have an equivalent organ; the bone marrow is often both the site of hematopoiesis and B cell development. The bursa is present in the cloaca of birds and is named after Hieronymus Fabricius who described it in 1621.