About H2 blockers. H2 blockers â also known as histamine 2 receptor antagonists â are medications that decrease the amount of acid the stomach produces. These drugs are used to treat various gastrointestinal disorders.2 blockers work by preventing the action of histamine, a substance released by the human immune system during allergic reactions. Histamine normally interacts with gastric H2 receptors to produce stomach acid. The H2 blockers inhibit this response and help reduce gastric acid output.
How long does it take to cook a 2.5-pound meatloaf? Recipes vary, but a meatloaf is generally baked for between 1 to 1 1/2 hours in a 350 to 400 degree oven. The type of meat and fillers used affect the cooking time.
Instructions. Preheat your oven to 325 degrees F. Place the frozen, foil-wrapped meatloaf in a shallow baking pan. Place the baking pan on the preheated oven's center rack. Bake the meatloaf for one hour.Remove the meatloaf from the oven using pot holders. Unwrap the foil, and brush the top of meatloaf with a glaze if desired. Place the meatloaf back into the oven and bake, uncovered, for another 30 to 40 minutes, or until it reaches the proper temperature.Place an instant-read food thermometer into the center of the meatloaf to check it's temperature, which should register 165 degrees F.lace the meatloaf back into the oven and bake, uncovered, for another 30 to 40 minutes, or until it reaches the proper temperature. Place an instant-read food thermometer into the center of the meatloaf to check it's temperature, which should register 165 degrees F.