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High BUN indicates increased protein breakdown, which is associated with decreased immune function. A study shows that patients with elevated BUN (> 20 mg/dl) have an increased risk of infection (R). High BUN is associated with increased mortality in critically ill patients (R, R, R, R).
Best Answer: The Anion Gap is increased when there are excessive anions/acids in the blood. This is either from too much acid production or insufficient removal of acids (either through the lungs, stomach, or kidneys).est Answer: The Anion Gap is increased when there are excessive anions/acids in the blood. This is either from too much acid production or insufficient removal of acids (either through the lungs, stomach, or kidneys).