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Preheat the oven to 450 degrees F. Season salmon with salt and pepper. Place salmon, skin side down, on a non-stick baking sheet or in a non-stick pan with an oven-proof handle. Bake until salmon is cooked through, about 12 to 15 minutes.
Cover the pan tightly with aluminum foil, and place the baking pan into the oven. Allow the salmon fillet to bake for approximately five minutes per ounce of weight. For example, if you have an 8-oz. salmon fillet, bake it for about 40 minutes.