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Wiktionary (0.00 / 0 votes) Rate this definition: disease (Noun). An abnormal condition of the body or mind that causes discomfort or dysfunction; distinct from injury insofar as the latter is usually instantaneously acquired. The tomato plants had some kind of disease that left their leaves splotchy and fruit withered. disease (Noun). Any abnormal or harmful condition, as of society, people's attitudes, way of living etc. disease (Verb). To cause unease; to annoy, irritate. disease (Verb). To infect with a disease.
disease of meaning. disease of meaning. Any disease or condition that potentially results from a life situation or circumstance that diminishes engagement and personal meaning and creates anomie, desperation, or the need to withdraw (e.g., into unipolar depression, substance abuse, alcoholism, self-inflicted injury).