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Wiktionary (0.00 / 0 votes) Rate this definition: disease (Noun). An abnormal condition of the body or mind that causes discomfort or dysfunction; distinct from injury insofar as the latter is usually instantaneously acquired. The tomato plants had some kind of disease that left their leaves splotchy and fruit withered. disease (Noun). Any abnormal or harmful condition, as of society, people's attitudes, way of living etc. disease (Verb). To cause unease; to annoy, irritate. disease (Verb). To infect with a disease.
A disease is a particular abnormal condition, a disorder of a structure or function, that affects part or all of an organism. The causal study of disease is called pathology.n humans, disease is often used more broadly to refer to any condition that causes pain, dysfunction, distress, social problems, or death to the person afflicted, or similar problems for those in contact with the person.