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Freebase(0.00 / 0 votes)Rate this definition: OSIsoft. OSIsoft, LLC is a worldwide manufacturer of Application software for real-time data infrastructure solutions, called the PI System. Founded in 1980, OSIsoft, LLC is privately held and headquartered in San Leandro, CA, with operations worldwide.
Â© Copyright 2014 OSIsoft, LLC. 2. Planning for a Successful OSIsoft PI System Implementation. OSIsoft PI System has the potential to be a large enterprise level system. to support whole corporate data management needs. Just because it. can handle the big data doesnât mean your program should immediately. start big - ensure success with an easy incremental road map!