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Children become overweight and obese for a variety of reasons. The most common causes are genetic factors, lack of physical activity, unhealthy eating patterns, or a combination of these factors. Only in rare cases is being overweight caused by a medical condition such as a hormonal problem. A physical exam and some blood tests can rule out the possibility of a medical condition as the cause for obesity. Although weight problems run in families, not all children with a family history of obesity will be overweight.
Therefore the most common causes of obesity are overeating and physical inactivity. Ultimately, body weight is the result of genetics, metabolism, environment, behavior, and culture.1  Genetics. 2  A person is more likely to develop obesity if one or both parents are obese.3  Genetics also affect hormones involved in fat regulation. 4  For example, one genetic cause of obesity is leptin deficiency.ltimately, body weight is the result of genetics, metabolism, environment, behavior, and culture. 1  Genetics. 2  A person is more likely to develop obesity if one or both parents are obese. 3  Genetics also affect hormones involved in fat regulation.