Heartworms are spread to dogs through mosquito bites. Up to 14 inches long, a heartworm lives in the heart and the arteries that carry blood from the heart to the lungs. Heartworms affect how the heart functions and how blood clots and is likely to cause death if untreated. Monthly heartworm preventives are effective.
missense mutation. A substitution of a single DNA nucleotide for another. This results in the transcription of a different amino acid than is normally found in the protein coded by the gene. Missense mutations are found in diseases such as sickle cell anemia.
Summary. A missense mutation is a permanent change in a DNA sequence in which one nucleotide is changed so that the corresponding RNA codon specifies a different amino acid during translation. This is what happens in individuals who have sickle-cell disease.To unlock this lesson you must be a Study.com Member.issense Mutation Example. Remember a missense mutation is a mutation in which one DNA nucleotide is switched out with another one in a way that changes the amino acid specified. When a missense mutation occurs in a DNA molecule, it changes one of the RNA codon sequences made during transcription.