What physicians need to know about restrictive covenants. Roy W. BreitenbachThe mention of restrictive covenants provokes an almost visceral reaction among most physicians. But keep in mind these covenants are, for the most part, enforceable.
An enzyme inhibitor is a molecule that binds to an enzyme and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. medicinal enzyme inhibitor is often judged by its specificity (its lack of binding to other proteins) and its potency (its dissociation constant, which indicates the concentration needed to inhibit the enzyme). A high specificity and potency ensure that a drug will have few side effects and thus low toxicity.
In non-competitive inhibition, the inhibitor binds to the enzyme at a site different than the active site. Binding to this site, however, changes the overall shape of the enzyme, slowing the processing of substrate into product once it is bound to the enzyme.n competitive inhibition, the inhibitor resembles the chemical structure of the true substrate, and it competes with the substrate for binding to the active site. The inhibitor is only able to bind the free enzyme, and cannot bind the substrate-enzyme complex.