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A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes. Antihistamines are drugs that inhibit the action of histamine in the body by blocking the receptors of histamine. There are two types of histamine receptors H1 and H2. When H1 receptors are stimulated by histamine it may produce allergic reactions such as itching, hay fever and rash or hives.
Histamine: A substance that plays a major role in many allergic reactions, dilating blood vessels and making the vessel walls abnormally permeable.Histamine is part of the body's natural allergic response to substances such as pollens.Antihistamines work by preventing the release of histamine from certain cells (mast cells) thereby blocking the allergic reaction.istamine is part of the body's natural allergic response to substances such as pollens. Antihistamines work by preventing the release of histamine from certain cells (mast cells) thereby blocking the allergic reaction.