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Quick Answer. Hand, foot and mouth disease in adults is caused by transmission from a person infected with the Coxsackievirus, according to Mayo Clinic. The virus is transmitted by personal contact such as exposure to nasal secretions, saliva, fluid from blisters, throat discharge or stool of an infected individual. Keep Learning.
Hand, foot and mouth disease is a viral infection caused by a strain of Coxsackie virus. It causes a blister-like rash that, as the name implies, involves the hands, feet and mouth. (Hand, foot and mouth disease is different than foot-and-mouth disease, which is an infection of cattle, pigs, sheep, goats and deer and is caused by a different virus.)