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To treat pain or menstrual cramps the normal dosage of Naproxen is 500 mg, changed with that of 250 mg every six to eight hours, according to the intensity of your pain.
At doses of naproxen greater than 500 mg/day there is less than proportional increase in plasma levels due to an increase in clearance caused by saturation of plasma protein binding at higher doses (average trough Css 36.5, 49.2, and 56.4 mg/L with 500, 1000 and 1500 mg daily doses of naproxen, respectively).