Necrotizing enterocolitis, usually called NEC, is a condition where the intestines become infected and can begin to die. The disease usually affects premature babies, although term babies may also get NEC. Necrotizing enterocolitis is a serious condition that may require surgery, and has a high morbidity and mortality rate.
Bordetella vaccines are given to puppies at about 12 to 18 weeks. According to Doodle Dog Shop the Bardatella vaccine is optional at 6-8 weeks. There are three year rated rabies virus such as Imrab-1 that can be given to puppies at twelve to sixteen weeks as well.
There is an injectable Bordatella vaccine, and one that is given intranasally (squirted into the nostrils). Neither vaccine will totally prevent infection with Bordatella. For the injectable vaccine, 2 doses must be given 3-4 weeks apart, and protection does not occur until 1-2 weeks after the second injection.