In the 2005 TNT study, 10,001 people with stable heart disease received either maximum-dose 80-mg LipitorÂ® or a standard dose of 10-mg LipitorÂ® daily. 1 Maximum-dose LipitorÂ® reduced levels of harmful low density lipoprotein (LDL) to an average of 77 mg/dL.This represented a substantial reduction in LDL.In comparison, standard-dose LipitorÂ® reduced LDL to an average level of 101 mg/dL, which was also a good result. Maximum-dose LipitorÂ® reduced levels of harmful low density lipoprotein (LDL) to an average of 77 mg/dL. This represented a substantial reduction in LDL. In comparison, standard-dose LipitorÂ® reduced LDL to an average level of 101 mg/dL, which was also a good result.
The units of a ribosome are often described by their Svedberg (s) values, which are based upon their rate of sedimentation in a centrifuge. The ribosomes in a eukaryotic cell generally have a Svedberg value of 80S and are comprised of 40s and 60s subunits. Prokaryotic cells, on the other hand, contain 70S ribosomes, each of which consists of a 30s and a 50s subunit.
Ribosomes are found in the cytoplasm of a cell. They are either free floating or bound to the endoplasmic reticulum. Groups of ribosomes stuck together are called polysomes. Most cells contain thousands of ribosomes, while a few specialized cells contain millions. Brain cells and the cells of the pancreas contain large concentrations of ribosomes since they produce a large amount of protein. slide 2 of 6. The Structure of Ribosomes Although ribosomes are called organelles, they don't have a membrane that holds the contents of the ribosome in one cohesive structure. Ribosomes are composed of ribosomal RNA (rRNA) and protein. Sixty percent of the structure is rRNA and 40 percent is protein. There are two subunits: a large subunit and a small subunit. They are labeled as 60s and 40s after the Svedberg values. The subunits of ribosomes are produced in the nucleolus, which is located in the nucleus of the cell. Ribosomal proteins enter the nucleolus and combine with four rRNA strands to produce the two subunits. The subunits leave the nucleus through the nuclear pores and combine in the cytoplasm.