Heart problems can cause sensations in other areas of the body besides your chest. Symptoms can include discomfort, pain, or pressure in the arms, back, neck, jaw, or stomach.
Infection with feline infectious peritonitis virus (FIPV), a feline coronavirus, frequently leads to death in spite of a strong humoral immune response. In previous work, we reported that infected monocytes, the in vivo target cells of FIPV, express viral proteins in their plasma membranes.These proteins are quickly internalized upon binding of antibodies.hese findings indicate that the viral antigen-antibody complexes were not internalized through any of the previously described pathways. Further characterization showed that this internalization process was independent from phosphatases and tyrosine kinases but did depend on serine/threonine kinases.
Alternative splicing generates mRNAs coding for the two capsid proteins (VP1 and VP2) and the non-structural protein NS1. These viral proteins are all synthesized in the cytoplasm, then imported into the nucleus. NS1 is essential for replication of the virus genome  but it is not a DNA polymerase. Instead, NS1 acts as an origin recognition protein, which specifically binds to double-stranded virus DNA and allows host DNA polymerase to replicate viral DNA, generating many single-stranded copies of the parvovirus genome.