He gave up dancing in 1938 to study sitar playing under court musician Allauddin Khan. After finishing his studies in 1944, Shankar worked as a composer, creating the music for the Apu Trilogy by Satyajit Ray, and was music director of All India Radio, New Delhi, from 1949 to 1956.han was a rigorous teacher and Shankar had training on sitar and surbahar, learned ragas and the musical styles dhrupad, dhamar, and khyal, and was taught the techniques of the instruments rudra veena, rubab, and sursingar. He often studied with Khan's children Ali Akbar Khan and Annapurna Devi.
Trisomy 18, also known as Edwards syndrome, is the second most common trisomy behind trisomy 21 (Down syndrome). It occurs in 1 in 5,000 live births and it is caused by the presence of an extra chromosome 18 and similar to Down syndrome. It is seen more commonly with increasing maternal age.
In most cases, Down syndrome occurs when there is an extra copy of chromosome 21. This form of Down syndrome is called Trisomy 21. The extra chromosome causes problems with the way the body and brain develop. Down syndrome is one of the most common causes of human birth defects.