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Relative abundances of phosphoglycerides and sphingolipids differ between membranes of ER and Golgi. Phospholipids synthesized in ER and sphingolipids synthesized in Golgi. Proportion of sphingomyelin as a percentage of total membrane lipid phosphorous is about six times as high in the Golgi membranes.
PS: Phosphatidylserines will carry a net charge of â1 at physiological pH and are composed of fatty acids similar to the phosphatidylethanolamines. The pathway for PS synthesis involves an exchange reaction of serine for ethanolamine in PE. This exchange occurs when PE is in the lipid bilayer of the a membrane.he pathway for fatty acid synthesis occurs in the cytoplasm, whereas, oxidation occurs in the mitochondria. The other major difference is the use of nucleotide co-factors. Oxidation of fats involves the reduction of FADH + and NAD + . Synthesis of fats involves the oxidation of NADPH.