The term cellulitis is commonly used to indicate a nonnecrotizing inflammation of the skin and subcutaneous tissues, a process usually related to acute infection that does not involve the fascia or muscles. Cellulitis is characterized by localized pain, swelling, tenderness, erythema, and warmth.
The regions on chromosomes 7 and 12 may coincide with the asthma and atopy loci on the same chromosomes. Polymorphism in the IL1 cluster on chromosome 2 has also been shown to influence the severity of the disease (95, 96).
Whether the association between the 15q24 susceptibility locus and lung cancer is direct (i.e., there is a gene in that region that causes lung cancer) or indirect (i.e., there is a gene in that region that causes tobacco addiction, which in turn causes lung cancer) remains to be determined.