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Author: Dr Amanda Oakley, Dermatologist, Hamilton, New Zealand,1999. Exfoliative keratolysis is a common skin condition in which there is focal peeling of the palms and less often the soles. It is also known as âkeratolysis exfoliativaâ, dyshidrosis lamellosa sicca, and âfocal palmar peelingâ.
Visage/Stockbyte/Getty Images. Exfoliative keratolysis is an excessive peeling of the skin on the palm of the hands and is sometimes called focal palm peeling.. The condition is preceded by an outbreak of air-filled blisters across the fingers and palms, which may be caused by eczema. These blisters inevitably burst, causing the palm peeling.