RE: Simpson Mending Plate for custom made wood truss. I think boo1 pretty welled summed it up. Based on experience my opinion would be that the liability you would be taking on if you try to show that the mend plates work, would be too high.
Isoniazid is often used as a protective treatment to reduce the risk of TB. D100 might be a medicine called doxycycline, which is a drug used to treatment many different things. Please ask your doctor or pharmacist to talk about this. These people will help you understand your medicine and what it is being used for.
Isoniazid has a boxed warning for severe and sometimes fatal hepatitis, which is age-dependent at a rate of 0.3% in people 21 to 35 years old and over 2% in those over age 50. Symptoms suggestive of liver toxicity include nausea, vomiting, abdominal pain, dark urine, right upper quadrant pain, and loss of appetite.