Heart problems can cause sensations in other areas of the body besides your chest. Symptoms can include discomfort, pain, or pressure in the arms, back, neck, jaw, or stomach.
Infection with feline infectious peritonitis virus (FIPV), a feline coronavirus, frequently leads to death in spite of a strong humoral immune response. In previous work, we reported that infected monocytes, the in vivo target cells of FIPV, express viral proteins in their plasma membranes.These proteins are quickly internalized upon binding of antibodies.hese findings indicate that the viral antigen-antibody complexes were not internalized through any of the previously described pathways. Further characterization showed that this internalization process was independent from phosphatases and tyrosine kinases but did depend on serine/threonine kinases.
Monocytes comprise 2 to 8 percent of the total population of circulating white blood cells. Monocytes originate in the bone marrow and develop into large macrophages in the bloodstream. Macrophages are the largest of the white blood cells and are responsible for engulfing cell debris, waste and harmful bacteria. Macrophages attack microbes by extending pseudopodia (feet-like extensions) around the cells and then destroy the microbe by releasing enzymes from inside the macrophage.