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Causes of Celiac Disease. Celiac disease is a condition that damages the digestive tract (specifically the small intestine), causing problems with absorption of vital vitamins, minerals, and nutrients. This damage occurs when a person consumes gluten, a substance found in grains such as wheat, barley, and rye.
1 Celiac is also linked to other autoimmune disorders and is now believed to lead to osteoporosis, anemia, infertility and cancer if left untreated.  Inheritance: the genetics of Celiac disease is simplest of the automimmune diseases, with autosomal recessive inheritance and an environmental factor, gluten.