1 An adenoma is a part of the gland that has walled itself off from the rest of the gland, forming noncancerous (benign) lumps that may cause an enlargement of the thyroid. Not all adenomas produce excess T-4, and doctors aren't sure what causes some to begin producing too much hormone.  Thyroiditis.
Scratching Itchy Skin Causes Brain To Release Hormone Serotonin, Intensifies Itchy Sensation. While a good scratch may temporarily relieve you of your itch, it actually stimulates serotonin in the brain that intensifies the itchy feeling.
There are several reasons why skin can become severely itchy including dry skin, nerve disorders, allergic reactions, taking certain drugs and pregnancy. Irritation to certain fabrics or cosmetics can also be a factor reports Mayo Clinic.