3. Pathways to an initiated cell. Initiation involves a change in the DNA sequence or quantity, i.e. either a gene mutation, chromosome mutation (breaks, rearrangements), or genome mutation (change in the number of chromosomes). Different pathways may result in these types of changes (Fig. 3).
It's like a drug withdrawal symptoms: Your intestine becomes irritable , when your body comes in a resting mood , what your brain may understand as abnormal mood after all ...You mentioned Forteo. Comment Helpful?
Norco withdrawal symptoms occur when the opiate receptors in the brain are no longer given the drug as a trigger for the intense feelings of pleasure and reward in the form of relaxation and contentment.