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Essential oils will last 12 - 24 hours in the body depending on several factors: viscosity, concentration, application method (massage or diffuser), skin type and to which body part the oils were applied. After entering the blood stream, essential oils are circulated to the tissues and organs.
Some important essential oil guidelines to remember: Essential oils should be diluted in a carrier oil to a maximum of 5% (see these 5 face oils for naturally clear, flawless skin). So since 1 ml is 20 drops, for every 1 ml of carrier oil, you would add 1 drop of EO. Be sure to do a patch test to make sure your skin does not have an adverse reaction to the oils.