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A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist. They are sometimes called blockers; examples include alpha blockers, beta blockers, and calcium channel blockers.
Noun. 1. antagonistic muscle - (physiology) a muscle that opposes the action of another; the biceps and triceps are antagonistic muscles. muscle, musculus-one of the contractile organs of the body. agonist-a muscle that contracts while another relaxes; when bending the elbow the biceps are the agonist. antagonist-a muscle that relaxes while another contracts; when bending the elbow the triceps are the antagonist. physiology-the branch of the biological sciences dealing with the functioning of organisms.