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Quick Answer. Hand, foot and mouth disease in adults is caused by transmission from a person infected with the Coxsackievirus, according to Mayo Clinic. The virus is transmitted by personal contact such as exposure to nasal secretions, saliva, fluid from blisters, throat discharge or stool of an infected individual. Keep Learning.
Hand-foot-and-mouth disease. This common illness is caused by a group of viruses known as enteroviruses. Coxsackievirus A16 is the enterovirus responsible for most cases of hand-foot-and-mouth disease. The illness occurs most commonly in babies and children under the age of 5, but adults may be affected, too. Fever, sore throat, reduced appetite, and malaise are early symptoms of infection.