Norepinephrine performs its actions on the target cell by binding to and activating adrenergic receptors. The target cell expression of different types of receptors determines the ultimate cellular effect, and thus norepinephrine has
While specific vitamins and minerals do not cause muscle cramps, a deficiency in potassium or magnesium can lead to sports-related leg cramping, according to Everyday Health. Additionally, a deficiency in vitamins E, A, and B causes cramping due to reduced circulation, as explained WeightTraining.com. Keep Learning.
Those who report two or more leg cramps in each week will continue in the study and will be randomized to vitamin D or placebo. After a two-week wash-in, subjects will take a vitamin D capsule (50,000 units) once daily for 10 days, followed by a once weekly vitamin D (50,000 units) maintenance dose for 7 weeks.