The term cellulitis is commonly used to indicate a nonnecrotizing inflammation of the skin and subcutaneous tissues, a process usually related to acute infection that does not involve the fascia or muscles. Cellulitis is characterized by localized pain, swelling, tenderness, erythema, and warmth.
The regions on chromosomes 7 and 12 may coincide with the asthma and atopy loci on the same chromosomes. Polymorphism in the IL1 cluster on chromosome 2 has also been shown to influence the severity of the disease (95, 96).
378 2.4 The Synuclein family in Parkinson disease The SNCA gene is located on chromosome 4q21-22 and is associated with susceptibility to PD and DLB. Alpha-synclein has two paralogous genes, beta- (SNCB; MIM#602569) and gamma-synuclein (SNCG; MIM#602998) with which it shares a highly conserved N-terminal domain.fter the detection of SNCA locus triplication, SNCA duplications were also reported in two families from France and Italy (Chartier-Harlin et al., 2004, Ibanez et al., 2004). Chartier-Harlin et al detected one duplication family among nine ADPD.