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If you do develop a flare-up of gout while taking allopurinol, continue taking the medication while your doctor prescribes additional treatment to settle the attack. Although allopurinol is taken without any side effects in most patients, around 10% do experience problems. A skin rash is the most common side effect.
If you're unable to take NSAIDs or if NSAIDs are ineffective, a medicine called colchicine can be used instead. Colchicine reduces some of the swelling and pain associated with a gout attack. It's best to have it with you at all times so you can use it at the first sign of a gout attack.