The term cellulitis is commonly used to indicate a nonnecrotizing inflammation of the skin and subcutaneous tissues, a process usually related to acute infection that does not involve the fascia or muscles. Cellulitis is characterized by localized pain, swelling, tenderness, erythema, and warmth.
The regions on chromosomes 7 and 12 may coincide with the asthma and atopy loci on the same chromosomes. Polymorphism in the IL1 cluster on chromosome 2 has also been shown to influence the severity of the disease (95, 96).
Oberâs team found that one of the mutations in the YKL-40 gene also correlated with a diagnosis of asthma and with impaired lung function, suggesting that increased levels of YKL-40 are part of the causal pathway that leads to asthma.