He gave up dancing in 1938 to study sitar playing under court musician Allauddin Khan. After finishing his studies in 1944, Shankar worked as a composer, creating the music for the Apu Trilogy by Satyajit Ray, and was music director of All India Radio, New Delhi, from 1949 to 1956.han was a rigorous teacher and Shankar had training on sitar and surbahar, learned ragas and the musical styles dhrupad, dhamar, and khyal, and was taught the techniques of the instruments rudra veena, rubab, and sursingar. He often studied with Khan's children Ali Akbar Khan and Annapurna Devi.
In most individuals with Trisomy 13 Syndrome, duplication of chromosome 13 is caused by spontaneous (de novo) errors during the division of reproductive cells in one of the parents (e.g., nondisjunction during meiosis).
Trisomy 21 occurs due to the nondisjunction of chromosome 21 during meiosis. It can occur during either the formation of ova or spermatozoa, resulting in an ovum or sperm cell with 22 chromosomes, and which lacks a chromosome 21, and another with 24 chromosomes, which has an extra copy of chromosome 21.