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In most cases, this common type of short-limbed dwarfism is related to a genetic mutation in the fibroblast growth factor receptor 3 gene. There are two possible causes of achondroplasia. One possible cause is a genetic mutation in the fibroblast growth factor receptor 3 (FGFR3) gene located on chromosome 4.The other possible cause is that the condition can be inherited from a parent with achondroplasia.here are two possible causes of achondroplasia. One possible cause is a genetic mutation in the fibroblast growth factor receptor 3 (FGFR3) gene located on chromosome 4.
Achondroplasia (from the Greek for without cartilage growth) is a condition that results in dwarfism. It is caused by a mutation in the FGFR3 (fibroblast growth factor receptor 3) gene.The FGFR3 gene is located on the short arm of chromosome 4 at position 16.3.Click FGFR3 Gene for more detailed information on how a defect in this gene can lead to achondroplasia. This article also discusses the role of FGFR3 in other conditions, such as bladder cancer.).