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If you do develop a flare-up of gout while taking allopurinol, continue taking the medication while your doctor prescribes additional treatment to settle the attack. Although allopurinol is taken without any side effects in most patients, around 10% do experience problems. A skin rash is the most common side effect.
These medicines may include: 1  Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, indomethacin, or naproxen. 2  Colchicine. 3  Corticosteroids, which may be given in pills or as a shot for cases of gout that don't respond to NSAIDs or colchicines.his can reduce how often you have gout attacks and how severe they are. These medicines may include: 1  Uricosuric agents, to increase elimination of uric acid by the kidneys. 2  Xanthine oxidase inhibitors, to decrease production of uric acid by the body.