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In most cases, this common type of short-limbed dwarfism is related to a genetic mutation in the fibroblast growth factor receptor 3 gene. There are two possible causes of achondroplasia. One possible cause is a genetic mutation in the fibroblast growth factor receptor 3 (FGFR3) gene located on chromosome 4.The other possible cause is that the condition can be inherited from a parent with achondroplasia.here are two possible causes of achondroplasia. One possible cause is a genetic mutation in the fibroblast growth factor receptor 3 (FGFR3) gene located on chromosome 4.
Achondroplasia is a bone growth disorder that causes disproportionate dwarfism. Dwarfism is defined as a condition of short stature as an adult. People with achondroplasia are short in stature with a normal sized torso and short limbs. It is the most common type of disproportionate dwarfism.The disorder occurs in approximately one in 25,000 live births, according to the Childrenâs Hospital of Philadelphia (CHOP). It is as common in males as females.t is the most common type of disproportionate dwarfism. The disorder occurs in approximately one in 25,000 live births, according to the Childrenâs Hospital of Philadelphia (CHOP). It is as common in males as females.