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NSAIDs. Nonsteroidal anti-inflammatory drugs work to help treat the symptoms of gout as well as other forms of arthritis. Over-the-counter NSAIDs such as naproxen sodium and prescription-level medications such as indomethacin can reduce the pain and swelling of a gout attack.
Appropriate adjustments were made for age, sex, body mass index, doctor visits, alcohol ingestion, comorbidities, and other drugs prescribed. Gout was proved by an index date of occurrence, as well as use of anti-gout medications (colchicine, probenecid, or NSAIDs). Some doctor subjectivity was allowed in the diagnosis of gout. Because previous studies suggested that losartan, unlike other angiotensin II receptor blockers (ARBs), lowers urate levels, this drug was studied separately from other members of its antihypertensive class.