Norepinephrine performs its actions on the target cell by binding to and activating adrenergic receptors. The target cell expression of different types of receptors determines the ultimate cellular effect, and thus norepinephrine has
While specific vitamins and minerals do not cause muscle cramps, a deficiency in potassium or magnesium can lead to sports-related leg cramping, according to Everyday Health. Additionally, a deficiency in vitamins E, A, and B causes cramping due to reduced circulation, as explained WeightTraining.com. Keep Learning.
Vitamin D Deficiency. If your legs feel tired and weak, it could be a sign of vitamin D deficiency, according to the American Journal of Clinical Nutrition. A vitamin D deficiency can cause your legs to feel heavy, tire easily and experience general muscle weakness. Your body can make its own vitamin D from exposure to sunlight.