Thus, researchers are unclear whether and to what extent elevated CRP levels are associated with psychological distress and depression in the general population. C-reactive protein (CRP) is a commonly used marker of inflammatory disease when CRP levels exceed 10 mg/L.
General Adaptation Syndrome. Selye defined stress as: âStress is the nonspecific response of the body to any demand, whether it is caused by, or results in, pleasant or unpleasant conditions.â. Selye identified three stages of adaptation which a person goes through in his General Adaptation Syndrome in 1936.ans Selye is often considered one of the early pioneers of modern stress theory.
Stress as a response model, initially introduced by Hans Selye (1956), describes stress as a physiological response pattern and was captured within his general adaptation syndrome (GAS) model (Figure 16.3). This model describes stress as a dependent variable and includes three concepts: Stress is a defensive mechanism. Stress follows the three stages of alarm, resistance, and exhaustion. If the stress is prolonged or severe, it could result in diseases of adaptation or even death.