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In most cases, this common type of short-limbed dwarfism is related to a genetic mutation in the fibroblast growth factor receptor 3 gene. There are two possible causes of achondroplasia. One possible cause is a genetic mutation in the fibroblast growth factor receptor 3 (FGFR3) gene located on chromosome 4.The other possible cause is that the condition can be inherited from a parent with achondroplasia.here are two possible causes of achondroplasia. One possible cause is a genetic mutation in the fibroblast growth factor receptor 3 (FGFR3) gene located on chromosome 4.
Narrowing of the spinal canal. Achondroplasia is one of the most common causes of short stature today. People with Achondroplasia have an average body size but disproportionate (shorter) limbs. The average height of a male is 4'4 and a female is 4'1.This is due to the long bones growing more slowly as opposed to the rest of the body, both in the womb and throughout childhood.Young children with Achondroplasia may have hearing, speech or breathing problems, but all of these are treatable.he average height of a male is 4'4 and a female is 4'1. This is due to the long bones growing more slowly as opposed to the rest of the body, both in the womb and throughout childhood. Young children with Achondroplasia may have hearing, speech or breathing problems, but all of these are treatable.