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Relative abundances of phosphoglycerides and sphingolipids differ between membranes of ER and Golgi. Phospholipids synthesized in ER and sphingolipids synthesized in Golgi. Proportion of sphingomyelin as a percentage of total membrane lipid phosphorous is about six times as high in the Golgi membranes.
In eukaryotes, it takes place both in the cytoplasm and in the nucleolus. It involves the coordinated function of over 200 proteins in the synthesis and processing of the three prokaryotic or four eukaryotic rRNAs, as well as assembly of those rRNAs with the ribosomal proteins.