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lose - allow to go out of sight; The detective lost the man he was shadowing after he had to stop at a red light 7. lose - fail to make money in a business; make a loss or fail to profit; I lost thousands of dollars on that bad investment!; The company turned a loss after the first year turn a loss break even - make neither profit nor loss
Webster Dictionary(0.00 / 0 votes)Rate this definition: 1  Loss(verb) the act of losing; failure; destruction; privation; as, the loss of property; loss of money by gaming; loss of health or reputation. 2  Loss(verb) the state of losing or having lost; the privation, defect, misfortune, harm, etc., which ensues from losing.