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Advanced Dementia. 1  Advanced dementia is a leading cause of death in the United States. 2  Features include profound memory deficits (e.g., inability to recognize family), minimal verbal communication, loss of ambulatory abilities, the inability to perform activities of daily living, and urinary and fecal incontinence.
They can also be caused by an enlarged, noncancerous prostate or by a urinary tract infection. Symptoms of advanced prostate cancer include: 1  Dull, deep pain or stiffness in the pelvis, lower back, ribs, or upper thighs; pain in the bones of those areas. 2  Loss of weight and appetite, fatigue, nausea, or vomiting. 3  Swelling of the lower extremities. 4  Weakness or paralysis in the lower limbs, often with constipation.