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If you do develop a flare-up of gout while taking allopurinol, continue taking the medication while your doctor prescribes additional treatment to settle the attack. Although allopurinol is taken without any side effects in most patients, around 10% do experience problems. A skin rash is the most common side effect.
Gout may be caused by some medical drugs, such as: 1  Diuretics (water tablets). 2  Some drugs such as ACE inhibitors or beta blockers used to treat hypertension also increase risk of gout. 3  Niacin which is used to lower cholesterol level. 4  Aspirin which is used to treat abnormal blood clots. 5  Some cancer medicines.