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The Cenozoic Era is the most recent of the three major subdivisions of animal history. The other two are the Mesozoic and Paleozoic Eras. The Cenozoic spans only about 65 million years, from the end of the Cretaceous Period and the extinction of non-avian dinosaurs to the present.he Cenozoic (65.5 million years ago to present) is divided into three periods: the Paleogene (65.5 to 23.03 million years ago), Neogene (23.03 to 2.6 million years ago) and the Quaternary (2.6 million years ago to present).
By the time the first mammals evolved 200 million years ago, however, dinosaurs were the dominant vertebrates. Mammals diversified in the shadow of the great archosaurs, and they remained fairly small and secretive until the non-avian dinosaurs were wiped out by a mass extinction 65 million years ago.