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Causes of Celiac Disease. Celiac disease is a condition that damages the digestive tract (specifically the small intestine), causing problems with absorption of vital vitamins, minerals, and nutrients. This damage occurs when a person consumes gluten, a substance found in grains such as wheat, barley, and rye.
Celiac Disease-Cause. Although the exact cause of celiac disease isn't known, having certain genes increases your risk. You are more likely to have these genes if you have a first-degree relative (mother, father, brother, sister, son, or daughter) who has celiac disease. Environmental factors, such as infections, may trigger changes in the small intestine of a person with these genes.