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The Cenozoic Era is the most recent of the three major subdivisions of animal history. The other two are the Mesozoic and Paleozoic Eras. The Cenozoic spans only about 65 million years, from the end of the Cretaceous Period and the extinction of non-avian dinosaurs to the present.he Cenozoic (65.5 million years ago to present) is divided into three periods: the Paleogene (65.5 to 23.03 million years ago), Neogene (23.03 to 2.6 million years ago) and the Quaternary (2.6 million years ago to present).
Fossil evidence shows that the first placental mammals evolved during the early Paleogene Period (65.6 million to 23 million years ago), some 200,000 to 400,000 years after the extinction of the dinosaurs at the end of the Cretaceous Period (145.5 million to 65.5 million years ago).