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Quick Answer. Hand, foot and mouth disease in adults is caused by transmission from a person infected with the Coxsackievirus, according to Mayo Clinic. The virus is transmitted by personal contact such as exposure to nasal secretions, saliva, fluid from blisters, throat discharge or stool of an infected individual. Keep Learning.
Hand-foot-and-mouth disease is a viral infection most often seen in infants and children younger than 10 years. It is most commonly caused by coxsackievirus A16. Coxsackieviruses are one type of enterovirus. Despite the similarity in names, hand-foot-and-mouth disease is a completely different infection than foot-and-mouth disease, which occurs only in animals and is caused by another type of virus.