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A taste receptor is a type of receptor which facilitates the sensation of taste. When food or other substances enter the mouth, molecules interact with saliva and are bound to taste receptors in the oral cavity and other locations. Molecules which give a sensation of taste are considered sapid.he TAS1R2 + TAS1R3 heterodimer receptor functions as the sweet receptor by binding to a wide variety of sugars and sugar substitutes. TAS1R2+3 expressing cells are found in circumvallate papillae and foliate papillae near the back of the tongue and palate taste receptor cells in the roof of the mouth.
The receptors for taste are located in specialized organs called taste buds which are numerous on the surface of the epithelium covering the tongue in humans and mamals. The taste buds are also located on the papillae on the upper surface of the tongue and also on the roof of the oral cavity, the pharynx and larynx.