Heart problems can cause sensations in other areas of the body besides your chest. Symptoms can include discomfort, pain, or pressure in the arms, back, neck, jaw, or stomach.
Infection with feline infectious peritonitis virus (FIPV), a feline coronavirus, frequently leads to death in spite of a strong humoral immune response. In previous work, we reported that infected monocytes, the in vivo target cells of FIPV, express viral proteins in their plasma membranes.These proteins are quickly internalized upon binding of antibodies.hese findings indicate that the viral antigen-antibody complexes were not internalized through any of the previously described pathways. Further characterization showed that this internalization process was independent from phosphatases and tyrosine kinases but did depend on serine/threonine kinases.
Macrophages develop from white blood cells called monocytes. Monocytes are the largest type of white blood cell. They have a large, single nucleus that is often kidney-shaped. Monocytes are produced in bone marrow and circulate in the blood anywhere from one to three days.acrophage Phagocytosis. Phagocytosis allows macrophages to get rid of harmful or unwanted substances in the body. Phagocytosis is a form of endocytosis in which matter is engulfed and destroyed by a cell. This process is initiated when a macrophage is drawn to a foreign substance by the presence of antibodies.