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lose - allow to go out of sight; The detective lost the man he was shadowing after he had to stop at a red light 7. lose - fail to make money in a business; make a loss or fail to profit; I lost thousands of dollars on that bad investment!; The company turned a loss after the first year turn a loss break even - make neither profit nor loss
Princeton's WordNet(4.87 / 15 votes)Rate this definition: 1  loss(noun) something that is lost. 2  loss(noun) gradual decline in amount or activity. 3  loss(noun) the act of losing someone or something.  loss, deprivation(noun) the disadvantage that results from losing 1  something. loss(noun) the experience of losing a loved  one.