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To treat pain or menstrual cramps the normal dosage of Naproxen is 500 mg, changed with that of 250 mg every six to eight hours, according to the intensity of your pain.
The clearance of naproxen is 0.13 mL/min/kg. Approximately 95% of the naproxen from any dose is excreted in the urine, primarily as naproxen (<1%), 6-0-desmethyl naproxen (<1%) or their conjugates (66% to 92%). The plasma half-life of the naproxen anion in humans ranges from 12 to 17 hours.