Remember, your problem statement is the backbone of the proposal and the feasibility report. By giving careful consideration to how you construct it now (for the proposal), you can use it when doing your research and writing for the proposal as well as the progress and the feasibility report.
http://www.ohsu.edu/research/skachlab/an... follow this link and it will take to a page where it describe very clearly the sequences of event that occurs during translocation. animated clips are also included which i believed will allow you to understand the process more clearly.
A translocation means that there is an unusual arrangement of the chromosomes. This can happen because: a) a change has arisen during the making of the egg or the sperm or around the time of conception. b) an altered chromosome arrangement has been inherited from either the mother or the father.