The term cellulitis is commonly used to indicate a nonnecrotizing inflammation of the skin and subcutaneous tissues, a process usually related to acute infection that does not involve the fascia or muscles. Cellulitis is characterized by localized pain, swelling, tenderness, erythema, and warmth.
In addition to confirming the previously identified asthma gene located on chromosome 17, researchers found another gene located on chromosome 1q31 was associated with an increased risk of childhood asthma in both children of European and African ancestry.
Pathophysiology. Bloom syndrome (congenital telangiectatic erythema) is caused by a mutation in both alleles of the gene designated BLM, traced to band 15q26.1. BLM encodes 1417 amino acids that code for a protein in the nuclear matrix of growing cells, which is a member of the RecQ family of helicases.hotosensitivity in Bloom syndrome patients is a result of increased susceptibility to 313-nm light, approaching the ultraviolet (UV)âA range. The minimal erythema dose threshold for both UV-A and UV-B are reduced.