1 An adenoma is a part of the gland that has walled itself off from the rest of the gland, forming noncancerous (benign) lumps that may cause an enlargement of the thyroid. Not all adenomas produce excess T-4, and doctors aren't sure what causes some to begin producing too much hormone.  Thyroiditis.
Scratching Itchy Skin Causes Brain To Release Hormone Serotonin, Intensifies Itchy Sensation. While a good scratch may temporarily relieve you of your itch, it actually stimulates serotonin in the brain that intensifies the itchy feeling.
Also, defects in the skin barrier could allow moisture out and germs in. Some people may have flare-ups of the itchy rash in response to certain substances or conditions. For some, coming into contact with rough or coarse materials may cause the skin to become itchy.