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Quick Answer. Hand, foot and mouth disease in adults is caused by transmission from a person infected with the Coxsackievirus, according to Mayo Clinic. The virus is transmitted by personal contact such as exposure to nasal secretions, saliva, fluid from blisters, throat discharge or stool of an infected individual. Keep Learning.
1 Hand, foot and mouth disease is caused by a virus (usually Coxsackie virus A16). 2  It causes blisters on the hands, feet, in the mouth. 3  Blisters can also be in the nappy area of young children.4  Hand, foot and mouth disease can be caused by several other viruses. The fever can be high, but often is mild. 2  Blisters on the hands and feet, and ulcers or blisters in the mouth appear 1-2 days after the first symptoms and may last for 2 â 7 days.