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The major target end organs for parathyroid hormone (PTH) action are the kidneys, skeletal system, and intestine. The primary response to parathyroid hormone (PTH) by the kidney is to increase renal calcium resorption and phosphate excretion.
Increased PTH causes the body to put more calcium into the blood. Increased PTH causes the bones to release their calcium into the blood. When the calcium in our blood goes too high, normal parathyroid glands STOP making PTH--they shut down.Calcium is the most important element for the nervous system, the muscular system, and the skeletal system.ncreased PTH causes the body to put more calcium into the blood. Increased PTH causes the bones to release their calcium into the blood. When the calcium in our blood goes too high, normal parathyroid glands STOP making PTH--they shut down.