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The Cenozoic Era is the most recent of the three major subdivisions of animal history. The other two are the Mesozoic and Paleozoic Eras. The Cenozoic spans only about 65 million years, from the end of the Cretaceous Period and the extinction of non-avian dinosaurs to the present.he Cenozoic (65.5 million years ago to present) is divided into three periods: the Paleogene (65.5 to 23.03 million years ago), Neogene (23.03 to 2.6 million years ago) and the Quaternary (2.6 million years ago to present).
One has to go back to a period 250 million years ago when the transition to mammals began in the form of mammal-like reptiles. Mammals evolved from a group of reptiles called the synapsids. These reptiles arose during the Pennsylvanian Period (310 to 275 million years ago).A branch of the synapsids called the therapsids appeared by the middle of the Permian Period (275 to 225 million years ago).HE EVOLUTION OF MAMMALS. The changes from a reptilian to a mammal's lifestyle is significant. Reptiles are cold-blooded, relying on external heat sources to raise their body temperature to a point necessary for activity.