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NSAIDs. Nonsteroidal anti-inflammatory drugs work to help treat the symptoms of gout as well as other forms of arthritis. Over-the-counter NSAIDs such as naproxen sodium and prescription-level medications such as indomethacin can reduce the pain and swelling of a gout attack.
Aspirin drives up the amount of uric acid in your blood. At high enough levels, uric acid deposits in joints (especially in the big toe and fingers) and forms the razor-sharp crystals responsible for gout. If you take low-dose aspirin to reduce your risk of heart disease, donât skip your daily pill for fear of gout.