Serotonin syndrome. Serotonin syndrome is a potentially life-threatening drug reaction that may occur following therapeutic drug use, inadvertent interactions between drugs, overdose of particular drugs, or the recreational use of certain drugs. The excess serotonin activity produces a spectrum of specific symptoms including cognitive, autonomic, and somatic effects. The symptoms may range from barely perceptible to fatal. Numerous drugs and drug combinations have been reported to produce serotonin syndrome.
middle finger (plural middle fingers) 1  The finger between the forefinger and the ring finger; this is the longest finger. 2  An obscene gesture directed towards another as an insult: a literal or sometimes figurative raising of the middle finger at someone.
1 Fig sign is a gesture made with the hand and fingers curled and the thumb thrust between the middle and index fingers, or, rarely, the middle and ring fingers, forming the fist so that the thumb partly pokes out. The Finger, an extended middle finger with the back of the hand towards the recipient, is an obscene hand gesture used in much of Western culture. 2  The middle finger presumably refers to an erect penis penetrating the female genetalia represented by the curled ring and index fingers.