1 The results of prophylactic measures for femoral head AVN have considerable variation, but certain generalizations can safely be stated. 2  Namely, the clinical results of core decompression alone deteriorate with more advanced lesions.
1 Melasma is very common skin ailment. It can occur to anyone, but young women with brownish tone are more likely to contract with it.  The condition is often linked with female hormonal changes. Change in level of estrogen and progesterone may cause melasma.
Melasma is thought to be the stimulation of melanocytes (cells in the epidermal layer of skin that produce a pigment called melanin) by the female sex hormones estrogen and progesterone to produce more melanin pigments when the skin is exposed to sun.