As degranulation occurs, it causes the mast cell or basophil to release a series of chemicals that orchestrate the allergic reaction. Within every mast cell or basophil are 500 to 1500 granules containing more than thirty different allergy-causing chemicals.
Urban design is an inter-disciplinary subject that unites all the built environment professions, including urban planning, landscape architecture, architecture, civil and municipal engineering.
Automotive design in this context is primarily concerned with developing the visual appearance or aesthetics of the vehicle, though it is also involved in the creation of the product concept. Automotive design is practiced by designers who may have an art background and a degree in industrial design or transportation design.