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The brain lesions can develop due to a number of reasons. Most prevalent causes of brain lesions are mentioned below: 1  Stroke, vascular injury or impaired supply of blood to the brain is perhaps the leading cause of lesions on the brain.
A lesion is an area of tissue that has been damaged through injury or disease. So a brain lesion is an area of injury or disease within the brain.While the definition sounds simple, understanding brain lesions can be complicated.That's because there are many types of brain lesions. lesion is an area of tissue that has been damaged through injury or disease. So a brain lesion is an area of injury or disease within the brain. While the definition sounds simple, understanding brain lesions can be complicated. That's because there are many types of brain lesions.