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Lung cancer occurs when the cells within the lung tissue are altered at a genetic level to mutate and multiply at an aggressive rate. The results of many studies on the effects of tobacco have shown that cigarette smoke carries numerous chemicals, called âmutagensâ, that cause lung tissue cells to mutate. Substances such as carbon monoxide, hydrogen peroxide and benzopyrene contained in cigarette smoke affect how cells change and grow.
Smoking can cause cancer and then block your body from fighting it: 1  Poisons in cigarette smoke can weaken the bodyâs immune system, making it harder to kill cancer cells. 2  Poisons in tobacco smoke can damage or change a cell's DNA.