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The brain lesions can develop due to a number of reasons. Most prevalent causes of brain lesions are mentioned below: 1  Stroke, vascular injury or impaired supply of blood to the brain is perhaps the leading cause of lesions on the brain.
Cancers that develop in the brain, such as a high-grade brain tumour, can cause paralysis, usually on one side of the body. Alternatively, cancers can spread (metastasise) from other parts of the body into the brain or spinal cord, leading to paralysis. severe head injury can cause brain damage. The brain's surface can tear or bruise as it bumps against the skull, damaging blood vessels and nerves. Paralysis can occur if a part of the brain that controls specific muscles is damaged during a severe head injury.