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When the visceral layer comes into contact with heart (not the great vessels) it is known as the epicardium. The epicardium is the layer immediately outside of the heart muscle proper (the myocardium). The epicardium is largely made of connective tissue and functions as a protective layer.he serous pericardium, in turn, is divided into two layers, the parietal pericardium, which is fused to and inseparable from the fibrous pericardium, and the visceral pericardium, which is part of the epicardium.
the outermost of the three layers of tissue that form the heart wall. It is composed of a single sheet of squamous epithelial cells overlying delicate connective tissue. The epicardium is the visceral portion of the serous pericardium and folds back on itself to form the parietal portion of the serous pericardium.Compare myocardium.t is composed of a single sheet of squamous epithelial cells overlying delicate connective tissue. The epicardium is the visceral portion of the serous pericardium and folds back on itself to form the parietal portion of the serous pericardium. Compare myocardium.