Another related concept is that neoadjuvant therapy acts on micrometastatic disease. The downstaging is then a surrogate marker of efficacy on undetected dissemination, resulting in improved longtime survival compared to the surgery-alone strategy.
Mexican-American Cesar Chavez (1927-1993) was a prominent union leader and labor organizer. Hardened by his early experience as a migrant worker, Chavez founded the National Farm Workers Association in 1962. His union joined with the Agricultural Workers Organizing Committee in its first strike against grape growers in California, and the two organizations later merged to become the United Farm Workers.
Cesar Chavez Foundation When Cesar Chavez began building what became the United Farm Workers of America on his birthday, March 31, 1962, he had a different vision of what a union movement could be. Cesar, Dolores Huerta and many others who would join him did a lot of research, studying why all the attempts to organize farm workers over the previous 100 years failed.