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1 Trauma is another important cause of brain lesions. 2  As mentioned before, trauma can either directly destroy brain tissues or can cause compression and delay of brain blood supply due to the formation of hematoma. 3  Sometimes inflammation causes brain lesions.
A lesion is an area of tissue that has been damaged through injury or disease. So a brain lesion is an area of injury or disease within the brain.While the definition sounds simple, understanding brain lesions can be complicated.That's because there are many types of brain lesions. lesion is an area of tissue that has been damaged through injury or disease. So a brain lesion is an area of injury or disease within the brain. While the definition sounds simple, understanding brain lesions can be complicated. That's because there are many types of brain lesions.