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Best Answer: Keratinization is the process by which lower layers of the dermis becomes the tough, insoluble, outer layer of the skin.This makes the outer layer of your skin almost completely waterproof, which helps maintain water balance in the body. Source(s): Tom Brady Â· 7 years ago.est Answer: Keratinization is the process by which lower layers of the dermis becomes the tough, insoluble, outer layer of the skin.
Pathophysiology. Keratosis pilaris (KP) is a genetically based disorder of hyperkeratinization of the skin. An excess formation and/or buildup of keratin is thought to cause the abrasive goose-bump texture of the skin. In these patients, the process of keratinization (the formation of epidermal skin) is faulty.eratosis pilaris (KP) is a genetically based disorder of hyperkeratinization of the skin. An excess formation and/or buildup of keratin is thought to cause the abrasive goose-bump texture of the skin. In these patients, the process of keratinization (the formation of epidermal skin) is faulty.