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Homeobox gene: A gene containing a short DNA sequence of about 180 base pairs referred to as a homeobox. Homeobox genes encode proteins that bind and regulate the expression of DNA in multicellular organisms.
Homeotic genes involved in spatial pattern control and development contain a conserved 180-bp sequence known as homeobox. This encodes a 60-amino-acid domain that binds to DNA.ithorax gene complex (3 homeobox genes affecting thoracic development). Normal â wings on 2nd thoracic segment and 2 halteres on 3rd thoracic segment (far left photo, halteres in white). Mutant â 3rd segment has wings so 2 sets of wings and no halteres.