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Early physical symptoms of elevated blood ammonia include fatigue, muscle weakness, loss of appetite, nausea, vomiting, diarrhea, pain in the back, sides or abdomen, or other symptoms of liver and kidney damage.
Severe cases may lead to coma and death. While ammonia is not the only factor in liver disease that contributes to hepatic encephalopathy, it typically plays a leading role. Treatments that reduce blood ammonia levels are usually at least partially effective at improving hepatic encephalopathy symptoms. Treating High Ammonia Levels