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1 Trauma is another important cause of brain lesions. 2  As mentioned before, trauma can either directly destroy brain tissues or can cause compression and delay of brain blood supply due to the formation of hematoma. 3  Sometimes inflammation causes brain lesions.
Complications of brain lesions may arise from the disease process itself or from the treatment modalities, and can range from minor complications (nausea and vomiting) to severe (symptoms become worse, seizures, coma, or even death).