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Best Answer: Keratinization is the process by which lower layers of the dermis becomes the tough, insoluble, outer layer of the skin.This makes the outer layer of your skin almost completely waterproof, which helps maintain water balance in the body. Source(s): Tom Brady Â· 7 years ago.est Answer: Keratinization is the process by which lower layers of the dermis becomes the tough, insoluble, outer layer of the skin.
Keratosis pilaris results from the buildup of keratin â a hard protein that protects skin from harmful substances and infection. The keratin forms a scaly plug that blocks the opening of the hair follicle. Usually many plugs form, causing patches of rough, bumpy skin. No one knows exactly why keratin builds up. But it may occur in association with genetic diseases or with other skin conditions, such as atopic dermatitis.