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Homeobox gene: A gene containing a short DNA sequence of about 180 base pairs referred to as a homeobox. Homeobox genes encode proteins that bind and regulate the expression of DNA in multicellular organisms.
An oncogene is a gene that has the potential to cause cancer cancer. Oncogenes were first described as retrovirus-encoded genes that produced tumors in birds and rodents. These genes were then shown to be dominant mutated forms of host genes. (proto-oncogenes) that had been picked up by the retroviruses. Generally they are in the form of a proto-oncogene in the normal cell. Most oncogenes require an additional step, such as mutations in another gene, or environmental factors like non-ionizing or ionizing radiation, or more likely a viral infection, to cause cancer. Many cancer drugs target the proteins encoded by oncogenes.