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1 After you eat, carbohydrates break down into sugar and enter the bloodstream in the form of glucose, a sugar that serves as a primary source of energy. 2  Normally, the pancreas responds by producing insulin, which allows sugar to enter the tissues.
Thus the working muscle can take in glucose even though little insulin is present. Another hormone from the pancreas, glucagon, stimulates the liver to release glucose to provide fuel for the muscles. The pancreas secretes two hormones, insulin and glucagon, to help maintain blood glucose levels.