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1 Trauma is another important cause of brain lesions. 2  As mentioned before, trauma can either directly destroy brain tissues or can cause compression and delay of brain blood supply due to the formation of hematoma. 3  Sometimes inflammation causes brain lesions.
Cancers that develop in the brain, such as a high-grade brain tumour, can cause paralysis, usually on one side of the body. Alternatively, cancers can spread (metastasise) from other parts of the body into the brain or spinal cord, leading to paralysis. severe head injury can cause brain damage. The brain's surface can tear or bruise as it bumps against the skull, damaging blood vessels and nerves. Paralysis can occur if a part of the brain that controls specific muscles is damaged during a severe head injury.