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Common side effects of Topamax include: diarrhea, paresthesia, nausea, ataxia, lack of concentration, diplopia, nervousness, dizziness, memory impairment, speech disturbance, anxiety, dysphasia, drowsiness, psychomotor disturbance, confusion, fatigue, visual disturbance, weight loss, depression, dysgeusia, mood changes, and anorexia.
1 Topamax can cause kidney stones. 2  This risk is increased for people taking carbonic anhydrase inhibitors (see Topamax Drug Interactions) or people following a ketogenic diet. 3  It is important to drink plenty of fluids to help prevent kidney stones. It is important to drink plenty of fluids to help prevent kidney stones. 2  One of the most common Topamax side effects is paresthesia (unusual sensations, such as burning, tingling, or pricking).