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Lumbar disc herniation with sciatica may be associated with increased CSF total protein. CSF protein concentration is slightly higher in males with depressive disorders than in women with similar diagnoses. CSF protein is within normal limits in 66% of patients with multiple sclerosis.
Protein levels in blood are an important indicator of health. High levels can indicate dehydration. Low levels can indicate loss of protein from the blood, usually into the intestinal or urinary tract. The bulk of Total Protein is made up of several important proteins, globulin and albumin, both of which have critical roles in the body. Albumin is a critical protein that acts as the âspongeâ that keeps the liquid part of blood within the vessels. Excessive loss of albumin causes fluid to leak into the tissues, causing swelling (edema).