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By Mayo Clinic Staff. It's not clear what causes simple kidney cysts. One theory suggests that kidney cysts develop when the surface layer of the kidney weakens and forms a pouch (diverticulum). The pouch then fills with fluid, detaches and develops into a cyst. Symptoms.
Symptoms. Simple kidney cysts typically don't cause signs or symptoms. If a simple kidney cyst grows large enough, symptoms may include: Dull pain in your back or side; Fever; Upper abdominal pain; When to see a doctor. Make an appointment with your doctor if you have signs or symptoms of a kidney cyst. Causes. It's not clear what causes simple kidney cysts. One theory suggests that kidney cysts develop when the surface layer of the kidney weakens and forms a pouch (diverticulum).