There is a lack of studies specifically examining the relationship between change in depression severity over time in individuals with bipolar disorder and change in the nature and magnitude of abnormal neural activity during emotion and cognitive challenge tasks.he attainment of this goal can be facilitated by identifying biomarkers reflecting pathophysiologic processes in bipolar disorder, namely impaired emotion regulation, impaired attention, and distractibility, which persist during depression and remission and are not common to unipolar depression.
The Federalist (later known as The Federalist Papers) is a collection of 85 articles and essays written by Alexander Hamilton, James Madison, and John Jay (under the pseudonym Publius) promoting the ratification of the United States Constitution.
The Federalist is a collection of 85 articles and essays written under the pseudonym Publius by Alexander Hamilton, James Madison, and John Jay to promote the ratification of the United States Constitution. Seventy-seven of these essays were published serially in the Independent Journal, the New York Packet, and The Daily Advertiser between October 1787 and August 1788. A two-volume compilation of these and eight others was published in 1788 as The Federalist: A Collection of Essays, Written i