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Early physical symptoms of elevated blood ammonia include fatigue, muscle weakness, loss of appetite, nausea, vomiting, diarrhea, pain in the back, sides or abdomen, or other symptoms of liver and kidney damage.
Normal concentrations of ammonia do not rule out hepatic encephalopathy. Other wastes can contribute to changes in mental function and consciousness, and brain levels of ammonia may be much higher than blood levels. This can make correlation of a person's symptoms to ammonia blood levels difficult. A decreased level of ammonia may be seen with some types of hypertension, such as essential (high blood pressure of unknown cause) and malignant (very high blood pressure that occurs suddenly and quickly). ^ Back to top.