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Intrinsic pathway coagulation factor profile, aPTT, partial thromboplastin time, PTT, blood coagulation tests. The aPTT is one of several blood coagulation tests. It measures how long it takes your blood to form a clot. Normally, when one of your blood vessels is damaged, proteins in your blood called clotting factors come together in a certain order to form blood clots and quickly stop bleeding. The aPTT test can be used to look at how well those clotting factors are working.
Reference values for aPTT vary among laboratories, but generally range between 25 and 38 seconds. The aPTT of a newborn will usually be prolonged and may be up to 55 seconds at birth.It decreases to the adult range by 6 months of age. (Note: each lab has its own reference values based upon the equipment and reagents used.). The aPTT is the most commonly used test to monitor heparin therapy.The therapeutic goal for a patient being anticoagulated with heparin, is an aPTT approximately 1.5 to 2.5 times the mean normal value.Note: each lab has its own reference values based upon the equipment and reagents used.). The aPTT is the most commonly used test to monitor heparin therapy. The therapeutic goal for a patient being anticoagulated with heparin, is an aPTT approximately 1.5 to 2.5 times the mean normal value.