The Battle of Moore's Creek Bridge. Febuary 27, 1776 at Willmington, North Carolina. The news of the Battle of Lexington and Battle of Concord, received in North Carolina a month later, further weakened British authority. Unable to stem the tide of revolution in the colony, Governor Martin abandoned New Bern and fled to Fort Johnston on the lower Cape Fear, arriving there on June 2.
Ubiquitin: A small but extremely important protein that acts the kiss of death to other proteins. Ubiquitin consists of only 76 amino acids.In the normal course of events, proteins are inactivated by the attachment of ubiquitin to them, a process called ubiquitination. Ubiquitin acts as a tag by which the protein-transport machinery ferries a protein to the proteasome for degradation.Antagonizing this process are enzymes that remove ubiquitin from proteins. Ubiquitin is appropriately named since it is ubiquitous and is present in virtually all types of cells.biquitin acts as a tag by which the protein-transport machinery ferries a protein to the proteasome for degradation. Antagonizing this process are enzymes that remove ubiquitin from proteins. Ubiquitin is appropriately named since it is ubiquitous and is present in virtually all types of cells.
Mupirocin, an antibiotic, is used to treat impetigo as well as other skin infections caused by bacteria. It is not effective, however, against fungal or viral infections. Unlike other antibiotics which act on either bacterial DNA or the cellular walls of bacteria, mupirocin blocks the activity of an enzyme called isoleucyl-tRNA synthetase within the bacteria. This enzyme is necessary in order for the bacteria to make proteins. Without the ability to make proteins, the bacteria dies.