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Depo Provera Shot. Depo-Provera Shot. Depo-Provera, a contraception drug, is a synthetic hormone (progestin), which is injected under the skin. It is 95-99% effective in preventing pregnancy for 3 months. For continued protection against pregnancy, women must return every 3 months for another injection.
Depo-Provera is injected in to the muscle of your butÂ­tock. The injection will prevent pregnancy for three months and the birth control effects begin as soon as you have your first shot. The injection should be repeated every three months (11-15 weeks) as long as birth control protection is wanted.