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Intrinsic pathway coagulation factor profile, aPTT, partial thromboplastin time, PTT, blood coagulation tests. The aPTT is one of several blood coagulation tests. It measures how long it takes your blood to form a clot. Normally, when one of your blood vessels is damaged, proteins in your blood called clotting factors come together in a certain order to form blood clots and quickly stop bleeding. The aPTT test can be used to look at how well those clotting factors are working.
1 The partial thromboplastin time (PTT) and activated partial thromboplastin time (APTT) may be normal in people who have inherited bleeding disorders but have only mild symptoms. 2  The APTT is used to check treatment of people who are using heparin or other blood-thinning medicine to prevent blood clots. A longer-than-normal PTT or APTT can be caused by liver disease, kidney disease (such as nephrotic syndrome), or treatment with blood thinners, such as heparin or warfarin (Coumadin). 2  A longer-than-normal PTT may be caused by conditions such as antiphospholipid antibody syndrome or lupus anticoagulant syndrome.