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Depo Provera Shot. Depo-Provera Shot. Depo-Provera, a contraception drug, is a synthetic hormone (progestin), which is injected under the skin. It is 95-99% effective in preventing pregnancy for 3 months. For continued protection against pregnancy, women must return every 3 months for another injection.
With Depo it's more common to be between 3 - 18 months or longer. The time varies in every woman and can be from 2-3 months to 12-18 months .The length of time you use Depo-Provera usually has no effect on how long it takes you to become pregnant.