1 The results of prophylactic measures for femoral head AVN have considerable variation, but certain generalizations can safely be stated. 2  Namely, the clinical results of core decompression alone deteriorate with more advanced lesions.
1 Melasma is very common skin ailment. It can occur to anyone, but young women with brownish tone are more likely to contract with it.  The condition is often linked with female hormonal changes. Change in level of estrogen and progesterone may cause melasma.
If skin discoloration occurs and changes the texture of your skin, the shape or the color, then itâs best to speak with the doctor to rule out potential skin cancer. Melasma â this condition is caused by the body irregularly producing estrogen and progesterone.