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On a more subtle level, the effect of ammonia on the brain include reduced cognition, lack of focus, diminished motivation, loss of sense of self, heightened emotionality and extreme mental fog. All commonly found symptoms these days.
Severe cases may lead to coma and death. While ammonia is not the only factor in liver disease that contributes to hepatic encephalopathy, it typically plays a leading role. Treatments that reduce blood ammonia levels are usually at least partially effective at improving hepatic encephalopathy symptoms. Treating High Ammonia Levels