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1 Trauma is another important cause of brain lesions. 2  As mentioned before, trauma can either directly destroy brain tissues or can cause compression and delay of brain blood supply due to the formation of hematoma. 3  Sometimes inflammation causes brain lesions.
The hypothesis suggests that white matter lesions may lead to disrupted structural connectivity within the brain along what are known as neural âtracks.â These disruptions could then lead to functional deficits, in turn contributing to behavioral impairments.