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As enzymes are made up of protein, they can be denatured by the means of physical action like due to change in pH, temp. and pressure, or by cemical procedure by acting some enzymes on them they can be denatured. 5 people found this useful.
What are Enzymes... An enzyme is a protein that acts as a catalyst. The enzyme is responsible for accelerating the rate of a reaction in which various substrates are converted to products through the formation of an enzyme-substrate complex.o enzymes break down any molecule or just specific ones and how specific do they get: (Above). The specificity of an enzyme for it's substrate is generally a function of the enzyme's active site or binding site. The structure of the protein determines the range of substrates or keys that can fit into the lock.