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As enzymes are made up of protein, they can be denatured by the means of physical action like due to change in pH, temp. and pressure, or by cemical procedure by acting some enzymes on them they can be denatured. 5 people found this useful.
1. Enzymes are proteins that are specific and they do almost all the work within a cell. 2. Enzymes are not used up or changed when breaking down a substrate and can perform the same action over and over very quickly. 3. Under certain conditions, enzymes are denatured. This happens when the protein molecule loses its proper shape and can no longer function.