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An afferent pupillary defect is an eye condition where one eye is less sensitive to light, and will not contract as sharply in response to light as the unaffected eye.This can be a sign of optic nerve damage, tumor, glaucoma, and a number of other eye issues.n afferent pupillary defect may be a sign of damage to the optic nerve. An afferent pupillary defect may be a sign of glaucoma or other eye conditions.
Pupil dilation is simply an indication of physiological arousal. The pressure of trying to pass off a lie causes a general stress response in many people, thus leading to adrenaline release, which causes pupil dilation. Hence it sometimes being used as a part of a lie detection protocol. Remember, if someone's pupils are dilated, that doesn't mean they are lying - they could just as easily have knocked down an espresso, be really excited about the topic, or even be afraid that you think they're lying when they're not. Context and other indicators are very important.