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A third Parkinson's disease medication option for drug-induced parkinsonism patients, MAO B inhibitors prevent the breakdown of dopamine by inhibiting the activity of the enzyme monoamine oxidase B, or MAO B. Options of MAO B inhibitors include selegiline and rasagiline.
As already indicated, the most important side-effects of typical antipsychotics are those involving the extrapyramidal system. There are four types of EPS, namely parkinsonian symptoms, dystonia, akathisia and tardive dyskinesia (TD). Drug-induced parkinsonism typically manifests in tremor, rigidity and brady-kinesia, and usually occurs within days or weeks of the initiation of therapy.