12/30/2016. Where We Are. The Savannah River Site (SRS), a 310 square mile (198,046 acres) Department of Energy site, is located in the sand-hills region of South Carolina. It encompasses parts of Aiken, Barnwell and Allendale counties and is bordered on the west by the Savannah River and Georgia.
The NOD2 gene provides instructions for making a protein that plays an important role in immune system function. The NOD2 protein is active in some types of immune system cells (including monocytes, macrophages, and dendritic cells), which help protect the body against foreign invaders such as viruses and bacteria.rohn disease-increased risk from variations of the NOD2 gene. Approximately 40 variations in the NOD2 gene have been associated with an increased risk of Crohn disease, a complex disorder of the digestive system.
Prostaglandin E2: One of the prostaglandins, a group of hormone-like substances that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation.rostaglandin E2 (PGE-2) is released by blood vessel walls in response to infection or inflammation that acts on the brain to induce fever. The enzyme mPGES-1 is involved in the production of PGE2 and is an important switch for activating the fever response.