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Depo Provera Shot. Depo-Provera Shot. Depo-Provera, a contraception drug, is a synthetic hormone (progestin), which is injected under the skin. It is 95-99% effective in preventing pregnancy for 3 months. For continued protection against pregnancy, women must return every 3 months for another injection.
3. There is no estimated time frame that your period will return after stopping Depo Provera. Some women get their periods right away, and some women find that they are still waiting on the return of their periods six months or more after stopping their depo shot.