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By Mayo Clinic Staff. It's not clear what causes simple kidney cysts. One theory suggests that kidney cysts develop when the surface layer of the kidney weakens and forms a pouch (diverticulum). The pouch then fills with fluid, detaches and develops into a cyst. Symptoms.
Polycystic kidney disease (PKD) causes numerous cysts to grow in the kidneys. If too many cysts grow or if they get too big, kidney function can be affected.Most people do not develop symptoms until they are 30 to 40 years old and sometimes symptoms can be so mild as to go undiagnosed.olycystic kidney disease (PKD) causes numerous cysts to grow in the kidneys. If too many cysts grow or if they get too big, kidney function can be affected.