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Topic Overview. Uremia (uremic syndrome) is a serious complication of chronic kidney disease and acute kidney injury (also known as acute renal failure).remic syndrome may affect any part of the body and can cause: 1  Nausea, vomiting, loss of appetite, and weight loss. 2  Changes in mental status, such as confusion, reduced awareness, agitation, psychosis, seizures, and coma.
Classical signs of uremia are: progressive weakness and easy fatigue, loss of appetite due to nausea and vomiting, muscle atrophy, tremors, abnormal mental function, frequent shallow respiration and metabolic acidosis.t can be defined as an excess of amino acid and protein metabolism end products, such as urea and creatinine, in the blood that would be normally excreted in the urine. The Uremic Syndrome can be defined as the terminal clinical manifestation of kidney failure (also called renal failure).