There is a lack of studies specifically examining the relationship between change in depression severity over time in individuals with bipolar disorder and change in the nature and magnitude of abnormal neural activity during emotion and cognitive challenge tasks.he attainment of this goal can be facilitated by identifying biomarkers reflecting pathophysiologic processes in bipolar disorder, namely impaired emotion regulation, impaired attention, and distractibility, which persist during depression and remission and are not common to unipolar depression.
The Federalist (later known as The Federalist Papers) is a collection of 85 articles and essays written by Alexander Hamilton, James Madison, and John Jay (under the pseudonym Publius) promoting the ratification of the United States Constitution.
The Federalist Papers. Collection of essays advocating the ratification of the U. S. Constitution, published 1787-88. The Federalist Papers are considered by many to be among the founding classics of American political thought, along with the Declaration of Independence, the Constitution, and the Bill of Rights.