Another related concept is that neoadjuvant therapy acts on micrometastatic disease. The downstaging is then a surrogate marker of efficacy on undetected dissemination, resulting in improved longtime survival compared to the surgery-alone strategy.
Mexican-American Cesar Chavez (1927-1993) was a prominent union leader and labor organizer. Hardened by his early experience as a migrant worker, Chavez founded the National Farm Workers Association in 1962. His union joined with the Agricultural Workers Organizing Committee in its first strike against grape growers in California, and the two organizations later merged to become the United Farm Workers.
Cesar Chavez leads a national boycott against the California table grape growers who will not sign a contract with the union. The campaign becomes known as âLa Causa.â. Chavez goes on a 25-day spiritual fast to protest the violence being used against the striking farmworkers and to draw attention to their struggle. The act attracts enormous national attention and the fast reaffirms the movementâs belief in non-violence and Chavezâs spiritual commitment to the cause.