A bone scan is done to: 1  Find bone cancer or determine whether cancer from another area, such as the breast, lung, kidney, thyroid gland, or prostate gland, has spread (metastasized) to the bone. 2  Help diagnose the cause or location of unexplained bone pain, such as ongoing low back pain.
June 13, 1720, cyclical sign kanoe-ne: The date the original Gohonzon was transcribed by Nichikan Shonin. Cyclical sign refers to one of sixty calendar signs, which are based on the twelve animal signs of the Chinese zodiac and the ten elements of nature according to old Chinese traditions.
The shogunate was officially established in Edo on March 24, 1603, by Tokugawa Ieyasu. The period came to an end with the Meiji Restoration on May 3, 1868, after the fall of Edo. revolution took place in the centuries from the time of the Kamakura shogunate, which existed with the Tenno 's court, to the Tokugawa, when the bushi became the unchallenged rulers in what historian Edwin O. Reischauer called a centralized feudal  form of government.