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The reduction in the rate of systolic ejection following elevation of aortic pressure leads to changes in cardiac output opposite to alteration in peripheral resistance, thus tending to maintain a relatively constant arterial pressure.
So, the heart imparts enough energy to the blood to move it, against the random forces of nature such as inertia, gravity and vascular resistance (friction), through the cardiovascular system. This energy causes the blood to exert a pressure against the walls of the different blood vessels through which it flows.he answer to this question is that to keep the blood flow (Q) stable within a given organ or tissue the body must be able to adjust the vascular resistance (R), up or down, to compensate for the changes in perfusion pressure (P). Remember Q = P/R.