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As enzymes are made up of protein, they can be denatured by the means of physical action like due to change in pH, temp. and pressure, or by cemical procedure by acting some enzymes on them they can be denatured. 5 people found this useful.
Temperature and enzymes. As the temperature increases, so does the rate of reaction. But very high temperatures denature denature: disable by changing the normal qualities or nature of something enzymes. The graph shows the typical change in an enzyme's activity with increasing temperature.