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Carrier-mediated transport enables molecules with low lipid solubility to traverse the blood-brain barrier. Glucose from blood enters the brain by a transport protein. Glucose is the primary energy substrate of the brain. Glucose transport protein (GLUT-1) is highly enriched in brain capillary endothelial cells. These transporters carry glucose molecules through the blood brain barrier.
The answer is because of the blood-brain barrier. This layer of cells keeps your brain safe from pathogens and other toxins. It is composed of brain cells and blood vessel cells. It plays a crucial role in protecting the most important organ in your body: the brain. The blood-brain barrier is like the moat outside a castle, preventing harmful invaders from entering.