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1 Trauma is another important cause of brain lesions. 2  As mentioned before, trauma can either directly destroy brain tissues or can cause compression and delay of brain blood supply due to the formation of hematoma. 3  Sometimes inflammation causes brain lesions.
Brain lesions are defects that occur from injury or disease. Causes during fetal development can include bleeding in the brain, infections, toxins, asphyxia, and many others. Lesions typically result from an incident or event that causes brain tissue death.