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By Mayo Clinic Staff. It's not clear what causes simple kidney cysts. One theory suggests that kidney cysts develop when the surface layer of the kidney weakens and forms a pouch (diverticulum). The pouch then fills with fluid, detaches and develops into a cyst. Symptoms.
Quick Answer. The cause of kidney cysts is not clear, but medical professionals theorize that the cysts develop when the kidney's surface layer forms a pouch and weakens, according to Mayo Clinic. Cysts develop when the pouch fills with fluid and detaches from the surface layer of the kidneys. Continue Reading.