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Puppies grow up quickly. They start to transition from their mother's milk onto solid foods, a process known as weaning, at around 3 weeks to 4 weeks of age. Before long, those little guys won't be nursing from their mother at all. Instead they'll be chowing down on puppy food.
It's best to consult a vet to make sure the weaning process is going smoothly. As the puppies increase their intake of solid food, mamma dog will naturally decrease her milk production. Most puppies are fully weaned and no longer rely on milk by the age of 7 to 8 weeks. This is when the puppies are getting ready to be adopted out to their new, loving homes.