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The bottom line. Elevated ferritin levels are usually due to causes such as acute or chronic inflammation, chronic alcohol consumption, liver disease, renal failure, metabolic syndrome, or malignancy rather than iron overload.
Patients with mildly increased ferritin levels (300-1000 Âµg/L) in whom iron overload is unlikely (that is, normal transferrin saturation) and other causes (such as liver disease, inflammatory disorders) are not evident.