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Best Answer: Keratinization is the process by which lower layers of the dermis becomes the tough, insoluble, outer layer of the skin.This makes the outer layer of your skin almost completely waterproof, which helps maintain water balance in the body. Source(s): Tom Brady Â· 7 years ago.est Answer: Keratinization is the process by which lower layers of the dermis becomes the tough, insoluble, outer layer of the skin.
Keratinization begins in the innermost layer of the epidermis.  Keratinization is the maturation and migration of skin cells. This  is where Keratin, a fibrous protein respo â¦ nsible for protective  properties of the dermis, is produced.eratinization begins in the innermost layer of the epidermis.  Keratinization is the maturation and migration of skin cells. This  is where Keratin, a fibrous protein respo â¦ nsible for protective  properties of the dermis, is produced.