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Understand how to freeze a wart. Over-the-counter cold kits use dimethyl ether and propane to freeze the wart and the tissue around the wart. Realize that the wart will not instantly fall off after treatment. It may take several treatments and up to 3 or 4 weeks before the wart gradually disappears.
The wart is frozen until it and 1 to 2 mm of surrounding skin have turned white (Figure 15) . A repeat freeze after thawing causes more effective tissue destruction than a single freeze. The affected tissue turns red or blisters over the next one to two days, then gradually sloughs off over the following weeks.