reflux esophagitis has improved dramatically since PPIs became available in 1989. PPIs provide rapid symptomatic relief and heal-ing of esophagitis in the highest percentage of patients. A systematic review of 7 trials that evalu-. Esophagitis Asthma Reflux in infants with laryngomalacia: results of 24-hour double-probe pH monitoring. Otolaryngol Head Neck Surg 1999; 120:860.
Soon after, John Wright of Birmingham, England discovered that potassium cyanide was a suitable electrolyte for gold and silver electroplating. Wright's associates, George Elkington and Henry Elkington were awarded the first patents for electroplating in 1840.
It is impossible to know the exact date that humans first began to mine gold, but some of the oldest known gold artifacts were found in the Varna Necropolis in Bulgaria. The graves of the necropolis were built between 4700 and 4200 BC, indicating that gold mining could be at least 7000 years old.