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The reduction in the rate of systolic ejection following elevation of aortic pressure leads to changes in cardiac output opposite to alteration in peripheral resistance, thus tending to maintain a relatively constant arterial pressure.
The walls of the blood vessels restrict where blood can flow, thereby creating friction as the blood flows against the walls. Two factors of blood vessels walls effect blood flow resistance: = Blood vessel length: The longer a blood vessel, the more resistance the blood will encounter as it flows. Blood vessel length is fixed, and therefore resistance due to blood vessel length is constant, in the adult.