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An afferent pupillary defect is an eye condition where one eye is less sensitive to light, and will not contract as sharply in response to light as the unaffected eye.This can be a sign of optic nerve damage, tumor, glaucoma, and a number of other eye issues.n afferent pupillary defect may be a sign of damage to the optic nerve. An afferent pupillary defect may be a sign of glaucoma or other eye conditions.
Trauma. A dilated pupil may be caused by any kind of trauma such as a damage of the nerves controlling the activities of the iris, an injury to the head or the eye, and iris sphincter. All these factors highly affect the consensual reactivity of the eyes to light and cause fixed and dilated pupils after trauma.ervous Problems. The neuropathic cause behind dilation of the pupils is the sympathetic stimulation of Î±1 adrenergic receptors involving the radial muscle and the parasympathetic stimulation involving the circular iris muscle cause the pupils to dilate.