There is a lack of studies specifically examining the relationship between change in depression severity over time in individuals with bipolar disorder and change in the nature and magnitude of abnormal neural activity during emotion and cognitive challenge tasks.he attainment of this goal can be facilitated by identifying biomarkers reflecting pathophysiologic processes in bipolar disorder, namely impaired emotion regulation, impaired attention, and distractibility, which persist during depression and remission and are not common to unipolar depression.
The Federalist (later known as The Federalist Papers) is a collection of 85 articles and essays written by Alexander Hamilton, James Madison, and John Jay (under the pseudonym Publius) promoting the ratification of the United States Constitution.
  Answer   the federalists papers were a series of papers written by John Jay,James Madison, and Alexander Hamilton. They were used to convince Virginia and New York to ratify the Constitution.hey were written to try and get public support for the approval of the constiution. The three best known federalist papers are the 10th and 51st by James Madison, and the 78t â¦ h, written by Alexander Hamilton. There were also anti-federalist papers.