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The brain lesions can develop due to a number of reasons. Most prevalent causes of brain lesions are mentioned below: 1  Stroke, vascular injury or impaired supply of blood to the brain is perhaps the leading cause of lesions on the brain.
Head injury. A severe head injury can cause brain damage. The brain's surface can tear or bruise as it bumps against the skull, damaging blood vessels and nerves. Paralysis can occur if a part of the brain that controls specific muscles is damaged during a severe head injury.Damage to the left side of the brain can cause paralysis on the right side of the body, and damage to the right side of the brain can cause paralysis on the left side of the body.Read more about severe head injury. severe head injury can cause brain damage. The brain's surface can tear or bruise as it bumps against the skull, damaging blood vessels and nerves. Paralysis can occur if a part of the brain that controls specific muscles is damaged during a severe head injury.