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1 The DNA + histone = chromatin definition: The DNA double helix in the cell nucleus is packaged by special proteins termed histones. 2  The formed protein/DNA complex is called chromatin.
Best Answer: Histones are the proteins closely associated with DNA molecules. They are responsible for the structure of chromatin and play important roles in the regulation of gene expression. Five types of histones have been identified: H1 (or H5), H2A, H2B, H3 and H4.H1 and its homologous protein H5 are involved in higher-order structures of chromatin. The other four types of histones associate with DNA to form nucleosomes. H1 (or H5) has about 220 residues.Other types of histones are smaller, each consisting of 100-150 residues. Each nucleosome consists of 146 bp DNA and 8 histones: two copies for each of H2A, H2B, H3 and H4.ive types of histones have been identified: H1 (or H5), H2A, H2B, H3 and H4. H1 and its homologous protein H5 are involved in higher-order structures of chromatin. The other four types of histones associate with DNA to form nucleosomes.