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On a more subtle level, the effect of ammonia on the brain include reduced cognition, lack of focus, diminished motivation, loss of sense of self, heightened emotionality and extreme mental fog. All commonly found symptoms these days.
Intestinal ammonia passes into the bloodstream and travels to the liver, which converts ammonia into urea. Urea subsequently passes from the body through the urine. High blood ammonia levels can occur with various forms of chronic liver disease, acute liver failure and gastrointestinal bleeding.