1 The results of prophylactic measures for femoral head AVN have considerable variation, but certain generalizations can safely be stated. 2  Namely, the clinical results of core decompression alone deteriorate with more advanced lesions.
1 Melasma is very common skin ailment. It can occur to anyone, but young women with brownish tone are more likely to contract with it.  The condition is often linked with female hormonal changes. Change in level of estrogen and progesterone may cause melasma.
Where it all started. I believe my melasma developed from the use of prescription medication. Desperate to eliminate my chronic acne and turning to Accutane, I inadvertently started a domino effect that would lead to problems with my hormones and liver. The problems only escalated with each drug.