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By Mayo Clinic Staff. It's not clear what causes simple kidney cysts. One theory suggests that kidney cysts develop when the surface layer of the kidney weakens and forms a pouch (diverticulum). The pouch then fills with fluid, detaches and develops into a cyst. Symptoms.
In most cases, simple kidney cysts do not cause symptoms and usually do not require treatment. However, in some cases simple kidney cysts can grow large enough and cause a dull pain in a person's back, side or upper abdomen. These cysts can also get infected, causing pain, fever and tenderness.They can burst, also causing pain. Simple kidney cysts rarely harm kidneys or impair their ability to function.t is possible to have one or more cysts in one or both kidneys. The exact cause of simple kidney cysts is not known but they tend to be more common as people age. Simple kidney cysts rarely cause problems and are different from polycystic kidney disease, which tends to run in families and can be more serious.