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Homeobox gene: A gene containing a short DNA sequence of about 180 base pairs referred to as a homeobox. Homeobox genes encode proteins that bind and regulate the expression of DNA in multicellular organisms.
Definition. noun, plural: homeotic genes. A developmental gene that specifies the anterior-posterior axis, as well as segment identity during the early embryonic development of certain organisms, such as metazoans.oun, plural: homeotic genes. A developmental gene that specifies the anterior-posterior axis, as well as segment identity during the early embryonic development of certain organisms, such as metazoans.