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Parkinson's diseaseback to top. As Parkinson's disease progresses, it often results in a progressive dementia similar to dementia with Lewy bodies or Alzheimer's. Symptoms: Problems with movement are common symptoms of the disease. If dementia develops, symptoms are often similar to dementia with Lewy bodies. Brain changes: Alpha-synuclein clumps are likely to begin in an area deep in the brain called the substantia nigra.
The Lewy body is an abnormal protein found microscopically in the brain of patients with this type of dementia. Symptoms of Lewy body dementia are similar to Alzheimer's, including impaired memory, confusion, and poor judgment.LBD also includes symptoms such as hallucinations and parkinsonian symptoms (shuffling gait, inability to stand straight, and shaking).ymptoms of Lewy body dementia are similar to Alzheimer's, including impaired memory, confusion, and poor judgment. LBD also includes symptoms such as hallucinations and parkinsonian symptoms (shuffling gait, inability to stand straight, and shaking).