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An afferent pupillary defect is an eye condition where one eye is less sensitive to light, and will not contract as sharply in response to light as the unaffected eye.This can be a sign of optic nerve damage, tumor, glaucoma, and a number of other eye issues.n afferent pupillary defect may be a sign of damage to the optic nerve. An afferent pupillary defect may be a sign of glaucoma or other eye conditions.
Dilated pupils occur when the pupils of the eyes increase in size. The pupils are commonly known as the round, black centers of the eyes. Dilation of the pupils is a normal response to low levels of light or darkness. This response helps a person to see better in situations of low light.Excessively dilated pupils (mydriasis) or unequal pupils can be a sign or symptom of a wide variety of mild to serious diseases, disorders and conditions.xcessively dilated pupils (mydriasis) or unequal pupils can be a sign or symptom of a wide variety of mild to serious diseases, disorders and conditions.