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Pancreas: This organ is located behind the stomach. It produces digestive enzymes and releases them into the duodenum. These enzymes include lipase, which breaks down fats, pancreatic amylase, which breaks down carbohydrates, proteases, which break down proteins.
The pancreas is the organ responsible for making and secreting digestive enzymes. Oral digestive enzymes are used when the pancreas is unable to produce enough digestive enzymes. The main digestive enzymes are. 1  proteases for digesting proteins, 2  lipases for digesting fats, and. 3  amylases for digesting carbohydrates.