Igneous rocks are formed from the solidification of molten rock material. There are two basic types. Intrusive igneous rocks crystallize below Earth's surface, and the slow cooling that occurs there allows large crystals to form. Examples of intrusive igneous rocks are diorite, gabbro, granite, pegmatite, and peridotite.
Systemic sclerosis or systemic scleroderma is an autoimmune or connective tissue disease. It is characterized by thickening of the skin caused by accumulation of collagen, and by injuries to the smallest arteries.ystemic sclerosis or systemic scleroderma is an autoimmune or connective tissue disease. It is characterized by thickening of the skin caused by accumulation of collagen, and by injuries to the smallest arteries.
The prognosis is generally good for limited cutaneous scleroderma persons who escape lung complications, but is worse for those with the diffuse cutaneous disease, particularly in older age and for males. Death occurs most often from lung, heart and kidney complications. In diffuse cutaneous disease, five-year survival is 70% and 10-year survival is 55%. The cause of scleroderma is unknown. It is an autoimmune condition, in which the body's immune system attacks healthy tissues. Strong associations with certain mutations in HLA genes have been identified.