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The bottom line. Elevated ferritin levels are usually due to causes such as acute or chronic inflammation, chronic alcohol consumption, liver disease, renal failure, metabolic syndrome, or malignancy rather than iron overload.
3 4 Raised ferritin levels therefore require further investigation in primary care to determine if they truly represent iron overload. It is critical to consider two broad categories of causes: Raised ferritin without iron overload. Raised ferritin due to iron overload.