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Early physical symptoms of elevated blood ammonia include fatigue, muscle weakness, loss of appetite, nausea, vomiting, diarrhea, pain in the back, sides or abdomen, or other symptoms of liver and kidney damage.
Symptoms of a high ammonia level, such as confusion or extreme sleepiness, may be treated with a medicine called lactulose, a laxative that works by reducing ammonia production in the intestines. It is common for newborns to have slightly high levels of ammonia in their blood.