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By Mayo Clinic Staff. It's not clear what causes simple kidney cysts. One theory suggests that kidney cysts develop when the surface layer of the kidney weakens and forms a pouch (diverticulum). The pouch then fills with fluid, detaches and develops into a cyst. Symptoms.
What causes simple kidney cysts? The cause of simple kidney cysts is not fully understood. Obstruction of tubulesâtiny structures within the kidneys that collect urineâor deficiency of blood supply to the kidneys may play a role. Diverticulaâsacs that form on the tubulesâmay detach and become simple kidney cysts. The role of genetic factors in the development of simple kidney cysts has not been studied. What are the symptoms of simple kidney cysts? Simple kidney cysts usually do not cause symptoms or harm the kidneys. In some cases, however, pain can occur between the ribs and hips when cysts enlarge and press on other organs. Sometimes cysts become infected, causing fever, pain, and tenderness.