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Homeobox gene: A gene containing a short DNA sequence of about 180 base pairs referred to as a homeobox. Homeobox genes encode proteins that bind and regulate the expression of DNA in multicellular organisms.
Abstract. The homeobox is a conserved sequence motif of about 180 base pairs found in homeobox genes. It encodes the homeodomain, which is a globular DNA-binding domain of about 60 amino acids.OU class. These homeobox genes encode a POU-specific domain upstream of a distinct type of homeodomain, the POU homeodomain. The POU-specific domain is a DNA-binding domain of about 80 amino acids that contains a helix-turn-helix motif like the homeodomain.