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Common side effects of Topamax include: diarrhea, paresthesia, nausea, ataxia, lack of concentration, diplopia, nervousness, dizziness, memory impairment, speech disturbance, anxiety, dysphasia, drowsiness, psychomotor disturbance, confusion, fatigue, visual disturbance, weight loss, depression, dysgeusia, mood changes, and anorexia.
Rating Newest Oldest. Best Answer: Topamax (topiramate) is an antiepileptic (AED) and anti-migraine drug that is well known to cause weight loss in some patients. Typically weight loss is minimal and it is heavily dose dependent (ie a larger dose causes more weight loss and anorexia (loss of appetite)).