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Medical Definition of Flare. Flare: 1. an exacerbation of a chronic disease. Sometimes referred to as a flare-up, a flare occurs when symptoms of a disease that has been present for a time suddenly worsen. A flare is a transient worsening in severity of a disease or condition that eventually subsides or lessens.
Full Definition of MANIFEST. transitive verb. : to make evident or certain by showing or displaying. â manÂ·iÂ·festÂ·er noun. See manifest defined for English-language learners. Their sadness was manifest in their faces. 2  His love for literature is manifest in his large library. 3  There was manifest confusion in the streets. 4  The argument, for all of its manifest inadequacies â¦ captured the national imagination and shaped subsequent religious discourse.