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Analgesics are drugs designed specifically to relieve pain. There are several types of analgesics: acetaminophen (Tylenol), which is available without a prescription, and a variety of opioid analgesics, which are available only with a prescription.
Analgesics reduce body aches, headaches and fever: 1  Acetaminophen (e.g. Tylenol, Panadol) is a painkiller and fever reducer. 2  Aspirin is a painkiller, fever reducer and anti-inflammatory with relatively few side effects.  Ibuprofen (e.g. Advil, Nuprin) is a painkiller, fever reducer and anti-inflammatory.