Dermatofibroma are common benign skin tumours that cause lumps in the skin and frequently cause concern upon discovery. The causes of dermatofibroma may include a reaction to trauma such as insect bites but the precise cause is often unclear.
Causes. It's not clear what causes simple kidney cysts. One theory suggests that kidney cysts develop when the surface layer of the kidney weakens and forms a pouch (diverticulum). The pouch then fills with fluid, detaches and develops into a cyst. 1  Symptoms. 2  Risk factors.
Main article: Polycystic kidney disease. Additional possible cause of nephropathy is due to the formation of cysts or pockets containing fluid within the kidneys. These cysts become enlarged with the progression of aging causing renal failure. Cysts may also form in other organs including the liver, brain and ovaries. Polycystic Kidney Disease is a genetic disease caused by mutations in the PKD1, PKD2, and PKHD1 genes.