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12 weeks of age: Administer the third combination injection and possibly a lyme vaccine inoculation. Generally a lyme vaccine is repeated two weeks later, then once a year. 16 weeks of age: Adminster the last combination vaccine. 12 to 16 weeks of age: Adminster rabies vaccine. The timing of this vaccine may depend on the laws in your area (since this can be a human disease, too). Confirm with your veterinarian and check your local and state laws.
Puppies should be with their mother until 8 weeks of age and then go to their new home. You should then contact your vet to find out when they can be vaccinated. Some puppies will need their first vaccination â and then a second one a couple of weeks later, depending on your vetâs advice.uppies should be with their mother until 8 weeks of age and then go to their new home. You should then contact your vet to find out when they can be vaccinated. Some puppies will need their first vaccination â and then a second one a couple of weeks later, depending on your vetâs advice.