In the same way that the removal of a single domino in the row would interrupt the sequence of toppling, Heinrich suggested that removal of one of the factors would prevent the accident and resultant injury; with the key domino to be removed from the sequence being number 3.
6The Impact of the Opioid Crisis on the Healthcare System. An analysis of the increase in per-patient charges from 2013 to 2015 shows that the rise in charges from. $50,490 to $63,356 for individuals with an opioid abuse or dependence diagnosis exceeds the per-.
The CDC reports that in 2015, drug overdoses involving an opioid accounted for 33,091 US deaths, constituting 63.1% of all drug overdose deaths. From 2014 to 2015, the age-adjusted opioid-involved death rate increased by 15.6%, from 9.0 to 10.4 per 100,000 in 2014.