Of 242 adult allogeneic HSCT patients who received voriconazole, 32 patients developed musculoskeletal pain and underwent subsequent serum fluoride measurement. Of those, 31 patients had a plasma fluoride measurement while on voriconazole. Twenty-nine (93.5%) had elevated fluoride concentrations (> 4 Î¼mol/L).
He was 84. The first CT machine took nine days to scan an object. Processing the information by computer then took 21 hours. Despite such formidable obstacles, researchers were undaunted.Hounsfield conceived the idea for a CAT scanner in 1967. By 1972, he had built a machine that produced detailed cross-sectional images of the brain in less than five minutes.
Doug Engelbart invented the computer mouse in the early 1960s in his research lab at Stanford Research Institute (now SRI International). The first prototype was built in 1964, the patent application for this X-Y position indicator for a display system was filed in 1967, and US Patent 3,541,541 was awarded in 1970.n the Web 8a. 1  MouseSite-the definitive website on the Mouse hosted by Stanford University, especially their Photos of the First Mouse page. 2  They also curate video of the 1968 demo and other significant archives from Doug Engelbart's work.