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Anti-mitochondrial antibodies (AMA) are autoantibodies, consisting of immunoglobulins formed against mitochondria, primarily the mitochondria in cells of the liver.mmunofluorescence staining pattern of AMA shown on stomach (top left), liver (top right), kidney (bottom left) and hep-20-10 cells (bottom right). Primary biliary cirrhosis is seen primarily in middle-aged women, and in those afflicted with other autoimmune diseases.
Antibodies are proteins made by the immune system to destroy foreign invaders. There are five major types of antibodies: immunoglobulin A (IgA), immunoglobulin G (IgG), immunoglobulin M (IgM), immunoglobulin E (IgE) and immunglobulin D (IgD). An IgG antibody helps to battle bacterial and viral infections. Comprising up to 80% of the all of these essential proteins, it is the smallest, yet most abundant, human antibody. Found in all bodily fluids, IgG is the only antibody that can protect a fetus by passing through the mother's placenta.