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Arava Oral. This medication is used to treat rheumatoid arthritis, a condition in which the body's defense system (immune system) fails to recognize the body as itself and attacks the healthy tissues around the joints. Leflunomide helps to reduce the joint damage/pain/swelling and helps you to move better.
1 Methotrexate is one of the most commonly used drugs in the treatment of rheumatoid arthritis. 2  It helps with pain and swelling and also slows the progression of arthritis over time.3  Methotrexate requires careful monitoring to reduce risk of liver injury and infections. Methotrexate is one of the most commonly used drugs in the treatment of rheumatoid arthritis. 2  It helps with pain and swelling and also slows the progression of arthritis over time.