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12 weeks of age: Administer the third combination injection and possibly a lyme vaccine inoculation. Generally a lyme vaccine is repeated two weeks later, then once a year. 16 weeks of age: Adminster the last combination vaccine. 12 to 16 weeks of age: Adminster rabies vaccine. The timing of this vaccine may depend on the laws in your area (since this can be a human disease, too). Confirm with your veterinarian and check your local and state laws.
You are required by law to have your dog vaccinated for rabies by a licensed veterinarian. A puppy should have its first rabies vaccination at 12 weeks of age. Vaccination Schedule: Your puppy (younger than 6 months) should begin its series of vaccinations at 6 - 8 weeks of age. The puppy/dog vaccination schedule your pet should follow is: DAPP Puppies should receive their first vaccination at 6 - 8 weeks, then every 2-3 weeks until adult dentition erupts (~5 months) Then booster annually Rabies Vaccination First rabies vaccination at 12 weeks, good for one year