Depression affects different people in different ways, but most of them experience some combination of the following symptoms: 1  Prolonged sadness or feelings of emptiness. 2  Feelings of helplessness or hopelessness. 3  Feelings of guilt or worthlessness.  Anger and 1  irritability. Restlessness.  Difficulty 1  concentrating. Fatigue.  Changes in sleep patterns.
Diphenhydramine (Benadryl Â® , Sominex Â® , and many other brand names) is an antihistamine that is used for a variety of different purposes. The approved uses may vary, depending on the particular product, and there are also a number of  off-label  uses for diphenhydramine.
Benadryl Injection (diphenhydramine hydrochloride) is an antihistamine used to treat life-threatening allergic reactions (anaphylaxis) along with epinephrine and other treatments.enadryl Injection is also used to treat nausea, vomiting and dizziness caused by motion sickness when medication cannot be given by mouth. The brand name of Benadryl Injection is discontinued, but generic versions may be available.