The presence of the chemical inhalants in the body makes the heart muscle more sensitive to epinephrine. When the surge of epinephrine reaches the heart, the heart suffers an arrhythmia (irregular heart beat). This massive arrhythmia kills the user in seconds.
Yu-Gi-Oh! (éâæ¯âç, YÅ«-Gi-Å!, lit. Game King) is a Japanese manga series about gaming written and illustrated by Kazuki Takahashi. It was serialized in Shueisha's Weekly ShÅnen Jump magazine between September 30, 1996 and March 8, 2004.
Shortly before his death, Kirito asks Akihiko why he created the death game, and Akihiko replies that he forgot why he did it long ago. It is hinted at several times that it may be related to a sort of god complex on the part of Akihiko, possibly related to some form of psychological disorder.