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2',3'-cyclic nucleotide 3'-phosphodiesterase, an oligodendrocyte-Schwann cell and myelin-associated enzyme of the nervous system.Sprinkle TJ. 2',3'-Cyclic nucleotide 3'-phosphohydrolase (E.C. 3.1.4.37; CNPase) is a myelin-associated enzyme.In central and peripheral nervous system tissues, the enzyme is localized almost exclusively in the two cell types that elaborate myelin, the oligodendrocyte and the Schwann cell, respectively.',3'-Cyclic nucleotide 3'-phosphohydrolase (E.C. 3.1.4.37; CNPase) is a myelin-associated enzyme.
The nitrogenous base, either a purine (adenine or guanine), or a pyrimidine (thymine, uracil or cytosine), is attached to the 1' carbon of the sugar. Nucleotides can exist in various phosphorylated forms, including nucleotide monophosphate (NMP), nucleotide di phosphate (NDP), or nucleotide triphosphate (NTP).his reaction leaves a triphosphate at 5' end of the dinucleotide and a 3' OH group at the other. Nucleic acid polymers are defined by their 5' phosphate ends and 3' OH ends. They have a direction. The reaction can continue; a dinucleotide can react with a nucleotide triphosphate to generate a trinucleotide.