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Anti-mitochondrial antibodies (AMA) are autoantibodies, consisting of immunoglobulins formed against mitochondria, primarily the mitochondria in cells of the liver.mmunofluorescence staining pattern of AMA shown on stomach (top left), liver (top right), kidney (bottom left) and hep-20-10 cells (bottom right). Primary biliary cirrhosis is seen primarily in middle-aged women, and in those afflicted with other autoimmune diseases.
There are five main types of antibodies: 1  IgM antibodies are the first to respond. 2  IgG antibodies are the next to respond. 3  IgA antibodies are secreted in body fluids such as tears, saliva, and mucus. 4  IgE antibodies are normally present in trace amounts and are important in allergic reactions.