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A ganglion is a fluid-filled swelling of the lining of a joint or tendon. Although ganglions can form on any part of the foot, they most often appear on the ankle or top of the foot. Ganglions tend to change size and usually grow slowly.
1 The pain in this case can be quite severe and the foot will experience swelling while being tender to the touch.  Ganglion cyst: A cyst is a fluid-filled capsule, and a ganglion cyst is one that forms around the joints or tendons of the foot.