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Arava Oral. This medication is used to treat rheumatoid arthritis, a condition in which the body's defense system (immune system) fails to recognize the body as itself and attacks the healthy tissues around the joints. Leflunomide helps to reduce the joint damage/pain/swelling and helps you to move better.
By Carol Eustice - Reviewed by a board-certified physician. Methotrexate (brand names Rheumatrex, Trexall, Otrexup, Rasuvo) is commonly prescribed to treat rheumatoid arthritis and certain other rheumatic conditions. Methotrexate was approved by the FDA in 1988 for the treatment of rheumatoid arthritis.