While its toxic effects can be damaging, the sensing of lipid A by the human immune system may also be critical for the onset of immune responses to gram-negative infection, and for the subsequent successful fight against the infection.
Waterloo County is located in South-Western Ontario. Waterloo County was created in 1838 from Townships from Halton and Simcoe and part of Indian lands. Prior to 1840 Waterloo County was part of Halton County, Simcoe District. The county seat was Berlin (now known as Kitchener).
On December 8, 1845 the Iowa State Register and Waterloo Herald was the first newspaper published in Waterloo. The name Waterloo supplanted the original name, Prairie Rapids Crossing shortly after Charles Mullan petitioned for a post office in the town.