Autoimmune hepatitis is a disease in which the bodyâs immune system attacks liver cells of the same organism. This causes the liver to become inflamed, resulting in hepatitis.
1 Gene mutations that occur after birth. 2  Most gene mutations occur after you're born and aren't inherited. 3  A number of forces can cause gene mutations, such as smoking, radiation, viruses, cancer-causing chemicals (carcinogens), obesity, hormones, chronic inflammation and a lack of exercise.
Altering nucleotide sequences most often results in nonfunctioning proteins. Mutations cause changes in the genetic code that lead to genetic variation and the potential to develop disease. Gene mutations can be generally categorized into two types: point mutations and base-pair insertions or deletions.Point mutations are the most common type of gene mutation.ccording to the National Human Genome Institute, most all disease have some sort of genetic factor. These disorders can be caused by a mutation in a single gene, multiple gene mutations, combined gene mutation and environmental factors, or by chromosome mutation or damage.