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If a nerve root is compressed in the spinal column it can send pain signals throughout the nerve, causing symptoms to radiate to other parts of the body. Common sources of upper back problems and shoulder pain include: 1  Degenerative disc disease (DDD) or other intervertebral disc problems. 2  Facet disease. 3  Osteoarthritis. 4  Stenosis. 5  Bone spurs.
Upper and middle back pain may be caused by: 1  Overuse, muscle strain, or injury to the muscles, ligaments, and discs that support your spine. 2  Poor posture.  Pressure on the spinal nerves from certain problems, such as a herniated disc.