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12 weeks of age: Administer the third combination injection and possibly a lyme vaccine inoculation. Generally a lyme vaccine is repeated two weeks later, then once a year. 16 weeks of age: Adminster the last combination vaccine. 12 to 16 weeks of age: Adminster rabies vaccine. The timing of this vaccine may depend on the laws in your area (since this can be a human disease, too). Confirm with your veterinarian and check your local and state laws.
Dogs that have never been vaccinated against rabies must receive their first vaccination at least 30 days prior to arrival. Puppies must not be vaccinated against rabies before 3 months of age, so the youngest that a puppy can be imported into the United States is 4 months of age.These requirements apply to all dogs including service animals. If your dog is imported from a rabies-free country, CDC does not require rabies vaccination.uppies can be vaccinated as early as 3 months of age and must be vaccinated at least 30 days before arrival in the United States. Therefore, dogs must be at least 4 months of age to be imported to the United States, unless they are being imported from a rabies-free country.