Zakynthos is a relatively small island so you can drive round it in one day, if you make an early start. Although the roads are generally not very busy, many roads in the north and west of the island are in a poor state of repair. A typically loop round the island is about 200km. Back to top 26.
Low cortisol levels can cause a condition known as Addison's disease. While rare, Addison's disease is an autoimmune disease that causes damage to the adrenal glands. Symptoms may start slowly, but they can be quite serious. Patients with Addison's disease can experience fatigue, muscle loss, weight loss, mood swings and changes to the skin.
In addition to persistent fatigue, these include subclinical depression, low sex drive, hypoglycemia (low blood sugar) and weakened immune response to infections. âThe symptoms of adrenal fatigue are many and varied,â Wilson explains, âbecause cortisol goes to virtually every part of the body. So when cortisol levels drop, lots of different systems are likely to be affected.