Of 242 adult allogeneic HSCT patients who received voriconazole, 32 patients developed musculoskeletal pain and underwent subsequent serum fluoride measurement. Of those, 31 patients had a plasma fluoride measurement while on voriconazole. Twenty-nine (93.5%) had elevated fluoride concentrations (> 4 Î¼mol/L).
He was 84. The first CT machine took nine days to scan an object. Processing the information by computer then took 21 hours. Despite such formidable obstacles, researchers were undaunted.Hounsfield conceived the idea for a CAT scanner in 1967. By 1972, he had built a machine that produced detailed cross-sectional images of the brain in less than five minutes.
The idea of this approach to scanning can be traced to three sources. In 1989, the first report of a practical spiral CT scanner was presented at the RSNA meeting in Chicago by Dr. Willi Kalender5. The spiral/helical CT scanners developed after 1989 were referred to a singleslice spiral/helical or volume CT scanners.