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The signs and symptoms of lupus that you experience will depend on which body systems are affected by the disease. The most common signs and symptoms include: 1  Fatigue and fever. 2  Joint pain, stiffness and swelling. 3  Butterfly-shaped rash on the face that covers the cheeks and bridge of the nose.
Lupus signs and symptoms include fatigue, headache, confusion, memory loss, photosensitivity, butterfly-shaped rash on the face, joint pain, stiffness, chest pain, shortness of breath, etc. Lupus is diagnosed with the help of blood tests, X-rays, and biopsy. Treatment for lupus is only symptomatic. There is no cure for this disease.