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Anti-mitochondrial antibodies (AMA) are autoantibodies, consisting of immunoglobulins formed against mitochondria, primarily the mitochondria in cells of the liver.mmunofluorescence staining pattern of AMA shown on stomach (top left), liver (top right), kidney (bottom left) and hep-20-10 cells (bottom right). Primary biliary cirrhosis is seen primarily in middle-aged women, and in those afflicted with other autoimmune diseases.
The mitochondrial antibody test measures the presence of anti-mitochondrial antibodies-antibodies which attack the mitochondria of the cells.owever, if the test results are abnormal, they will show the presence of the mitochondrial M2 antibody. Positive tests indicate cirrhosis of the liver, primary biliary cirrhosis, thyroiditis, rheumatoid arthritis, liver blockage, or autoimmune hepatitis.