Depression affects different people in different ways, but most of them experience some combination of the following symptoms: 1  Prolonged sadness or feelings of emptiness. 2  Feelings of helplessness or hopelessness. 3  Feelings of guilt or worthlessness.  Anger and 1  irritability. Restlessness.  Difficulty 1  concentrating. Fatigue.  Changes in sleep patterns.
Diphenhydramine (Benadryl Â® , Sominex Â® , and many other brand names) is an antihistamine that is used for a variety of different purposes. The approved uses may vary, depending on the particular product, and there are also a number of  off-label  uses for diphenhydramine.
What is diphenhydramine (Benadryl)? Diphenhydramine is an antihistamine. Diphenhydramine blocks the effects of the naturally occurring chemical histamine in the body. Diphenhydramine is used to treat sneezing; runny nose; itching, watery eyes; hives; rashes; itching; and other symptoms of allergies and the common cold.