Surfactant is a complex substance containing phospholipids and a number of apoproteins. This essential fluid is produced by the Type II alveolar cells, and lines the alveoli and smallest bronchioles.
William and Anne Shakespeare had three children. Their first child was Susanna, born a mere six months after the wedding of her parents. She was christened on May 26, 1583, and twins arrived in January, 1585.
Birth and childhood. William Shakespeare was probably born on about April 23, 1564, the date that is traditionally given for his birth. He was John and Mary Shakespeare's oldest surviving child; their first two children, both girls, did not live beyond infancy. Growing up as the big brother of the family, William had three younger brothers, Gilbert, Richard, and Edmund, and two younger sisters: Anne, who died at seven, and Joan.