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The signs and symptoms of lupus that you experience will depend on which body systems are affected by the disease. The most common signs and symptoms include: 1  Fatigue and fever. 2  Joint pain, stiffness and swelling. 3  Butterfly-shaped rash on the face that covers the cheeks and bridge of the nose.
People with lupus have periods in which they are feeling well, called remission, and periods of worsening symptoms, called flares. Lupus patients can often predict the onset of flares due to specific warning signs, such as worsening fatigue and/or onset of headache, fever, dizziness, rash, and/or pain (Phillips 1991).YPES OF LUPUS. The term lupus commonly refers to systemic lupus erythematosus, or SLE, but there are other types of lupus as well, each with distinct signs and symptoms (Firestein 2009). Systemic lupus erythematosus (SLE). This is the disease often simply referred to as lupus.