This occurs when a substance passes from the fluid in the tubular lumen through the apical membrane, across the cytosol , and then into the interstitial fluid.
Yes, it's potent stuff. Cat receive it either as an injection or orally. It takes effect in roughly half an hour, lasting about 8 hours before another administration is necessary. Cats usually react negatively to opiates, but buprenorphine is an exception. That's one reason vets use it if they can receive the necessary special certification.
How It Works. Buprenorphine is an opioid medicine similar to morphine, codeine, and heroin. It targets the same places in the brain that opioids do. It relieves drug cravings without giving you the same high as other opioid drugs.