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Home pregnancy tests are usually about 97% accurate, but this varies from brand to brand. In order to get the most accurate results, it is a good idea to wait for about a week after your period is due before testing. This allows more hCG to build up in your urine, which will allow for a more accurate test.
The day that you can take a pregnancy test really depends on the test. An EPT should be taken the first day of a missed period. However, there are tests that can be taken before your period is due to begin, such as a First Response test, and it can be taken up to 4 days before your expected period.