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Prostatitis is often difficult to treat, in part because several forms of the disease exist and the cause of the most common form is unknown. Some men experience acute flare-ups caused by a bacterial infection of the prostate. This acute bacterial prostatitis is associated with a sudden and continuous pain that lasts for several days. Some men have signs of inflammation, such as white blood cells in their semen, but not the painful symptoms of prostatitis.
The most frequent benign prostate conditions that cause an elevation in PSA level are prostatitis (inflammation of the prostate) and benign prostatic hyperplasia (BPH) (enlargement of the prostate). There is no evidence that prostatitis or BPH leads to prostate cancer, but it is possible for a man to have one or both of these conditions and to develop prostate cancer as well.