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Arava Oral. This medication is used to treat rheumatoid arthritis, a condition in which the body's defense system (immune system) fails to recognize the body as itself and attacks the healthy tissues around the joints. Leflunomide helps to reduce the joint damage/pain/swelling and helps you to move better.
Medicine choices. Medicines used to treat arthritis include: 1  Acetaminophen to help relieve pain. 2  Nonsteroidal anti-inflammatory drugs to reduce pain, swelling, and fever. 3  Tramadol to help relieve pain. 4  Steroid shots in the joint to reduce swelling. 5  Some antidepressants, such as duloxetine, to help relieve pain.