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A ganglion is a fluid-filled swelling of the lining of a joint or tendon. Although ganglions can form on any part of the foot, they most often appear on the ankle or top of the foot. Ganglions tend to change size and usually grow slowly.
A ganglion cyst is a round, fluid-filled lump of tissue that usually appears along tendons or joints. It typically occurs on the wrist or hand, but it can also appear on the ankle or foot. Ganglion cysts can be as large as an inch across.