In terms of structure, the humerus serves as a connection between the scapula and the elbow, where it links to the two lower arm bones. The humerus bone of the upper arm (the arm in anatomy refers only to the top part of the upper limb i.e. between the elbow and the shoulder).
FDA Approval for Denosumab. Use in Cancer. Denosumab is approved to treat: Giant cell tumor of the bone. It is used in adults and in adolescents whose bones have finished growing. This use is approved for the Xgeva brand of denosumab. Denosumab is approved to prevent and treat: Broken bones and other bone problems caused by solid tumors that have metastasized (spread) to bone. This use is approved for the Xgeva brand of denosumab. Osteoporosis in postmenopausal women who have a high risk of breaking bones. This use is approved for the Prolia brand of denosumab. Denosumab is also approved to increase bone mass in patients who are at high risk of breaking bones.
Immunoglobulin E (IgE) is an antibody that is produced by the bodyâs immune system in response to a perceived threat.It is one of five classes of immunoglobulins (A, G, M, D, and E) and is normally present in the blood in very small amounts. This test measures the amount of IgE in the blood.uring an initial exposure, also called sensitization, an allergic person produces an IgE specifically directed against that allergen. IgE binds to specialized white blood cells, resulting in the release of a number of substances, including histamine.