If you have calls to console.log in your Javascript, you will get an error in Internet Explorer. This is because there is no console variable (object) in the window name space. Sure you could take out all your console.log statements, but usually you need those around for a little while.
Common side effects of methadone include anxiety, nervousness, restlessness, insomnia, weakness, drowsiness, dry mouth, nausea, vomiting, diarrhea, constipation, loss of appetite, and decreased sex drive. Weight gain can also be a common side effect of methadone.ethadone is a medication used to relieve severe pain. It's also used to prevent withdrawal symptoms in people who are addicted to opiate drugs such as morphine, hydrocodone, oxycodone, and fentanyl.
On the one hand, methadone is an opiate itself, binding to and activating mu-opioid receptors in the brain. It's this action which makes methadone a an opiate substitute that reduces cravings for harder opiates with more abuse potential, like heroin, morphine or fentanyl. Methadone does block the euphoric or mood-elevating effects of harder opiates. In other words, methadone activates mu-opioid receptors (just like morphine or heroin), but in a manner that doesn't elicit euphoria.