Depression affects different people in different ways, but most of them experience some combination of the following symptoms: 1  Prolonged sadness or feelings of emptiness. 2  Feelings of helplessness or hopelessness. 3  Feelings of guilt or worthlessness.  Anger and 1  irritability. Restlessness.  Difficulty 1  concentrating. Fatigue.  Changes in sleep patterns.
Diphenhydramine (Benadryl Â® , Sominex Â® , and many other brand names) is an antihistamine that is used for a variety of different purposes. The approved uses may vary, depending on the particular product, and there are also a number of  off-label  uses for diphenhydramine.
diphenhydrAMINE hydrochloride, an antihistamine. indications It is prescribed in the treatment of hypersensitivity reactions, including rhinitis, skin rash, and pruritus, and in the treatment of motion sickness and insomnia. contraindications Asthma or known hypersensitivity to this drug prohibits its use.