Apart from changes in the pharmacokinetics of metabolites of midazolam, changes in the pharmacokinetics of midazolam also appear to be an issue in patients with impaired renal function. Changes in pharmacokinetics result from a reduction in plasma protein binding.he pharmacokinetics of both lorazepam and midazolam are described best by a 1-compartment pharmacokinetic model (Fig 1 and Fig 2). In general, a 2-compartment model is used for the description of the time course of the concentration of parent compounds in plasma after a single bolus injection.
Testing a door switch. NOTE: Before you begin to test a door interlock switch, first make sure your microwave oven is unplugged, and that your capacitor is discharged. A door switch is a simple on/off mechanism that prohibits the microwave from operating when the door is open. Microwave door switches are only an inch long.
...a wooden bench which was bolted to the floor. V-ed. 3 n-count A bolt on a door or window is a metal bar that you can slide across in order to fasten the door or window. I heard the sound of a bolt being slowly and reluctantly slid open. 4 verb When you bolt a door or window, you slide the bolt across to fasten it.