Depression affects different people in different ways, but most of them experience some combination of the following symptoms: 1  Prolonged sadness or feelings of emptiness. 2  Feelings of helplessness or hopelessness. 3  Feelings of guilt or worthlessness.  Anger and 1  irritability. Restlessness.  Difficulty 1  concentrating. Fatigue.  Changes in sleep patterns.
Diphenhydramine (Benadryl Â® , Sominex Â® , and many other brand names) is an antihistamine that is used for a variety of different purposes. The approved uses may vary, depending on the particular product, and there are also a number of  off-label  uses for diphenhydramine.
DIPHENHYDRAMINE (dye fen HYE dra meen) is an antihistamine. It is used to treat the symptoms of an allergic reaction. It is also used to treat Parkinson's disease. This medicine is also used to prevent and to treat motion sickness and as a nighttime sleep aid.