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For the language families subsumed under Khoisan, see Khoisan languages.  Khoisan  (/ËkÉÉªsÉËn/ ; also spelled Khoesaan, Khoesan or KhoeâSan) is a unifying name for two groups of peoples of Southern Africa, who share physical and putative linguistic characteristics distinct from the Bantu majority of the region.arious Y-chromosome studies since confirmed that the Khoisan carry some of the most divergent (oldest) Y-chromosome haplogroups. These haplogroups are specific sub-groups of haplogroups A and B, the two earliest branches on the human Y-chromosome tree.
The Khoisan believe strongly in a trickster deity who can be both foolish and wise. Khoisan is a term used by physical anthropologists to distinguish the aboriginal people of southern Africa from their black African farming neighbours.The original San hunter-gatherer groups lived on this land for about 100 000 years before the arrival of other black people and European settlers.he Khoisan people of the Northern Cape. The Khoisan people of the Northern Cape are descended from two different tribes. An amalgam of the original San hunter-gatherers and the later-arriving KhoiKhoi, they were virtually annihilated by subsequent settlers.