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Analgesics are drugs designed specifically to relieve pain. There are several types of analgesics: acetaminophen (Tylenol), which is available without a prescription, and a variety of opioid analgesics, which are available only with a prescription.
Opioid (narcotic) analgesics are derived from or related to the Opium. They bind to opioid receptors, which present in many regions of the nervous system and are involved in pain signalling and control. There are four groups of opioid receptors: delta, kappa, mu, and sigma. Non-onopioid (non-narcotic) include acetaminophen, the most commonly used over-the-counter analgesic.