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Renal tubular acidosis, a kidney condition that makes the urine more acidic. Kidney stones form more easily in acidic urine. ... Uric acid, calcium oxalate, and cystine stones form more readily in acidic urine, so this prevention strategy hinges on keeping the urine slightly alkaline.
Avoid products such as cranberry juice or ascorbic acid because these items may increase urine acid levels. Step 6. Urinate when you first feel the urge. Holding urine in the bladder causes a decrease in water content in the urine and makes it more acidic. Step 7. Stop taking medications that cause a decrease in urine pH levels, which is acidic urine. Medications that may cause acidic urine include thiazide diuretics and ammonium chloride, according to MedlinePlus.