In terms of structure, the humerus serves as a connection between the scapula and the elbow, where it links to the two lower arm bones. The humerus bone of the upper arm (the arm in anatomy refers only to the top part of the upper limb i.e. between the elbow and the shoulder).
FDA Approval for Denosumab. Use in Cancer. Denosumab is approved to treat: Giant cell tumor of the bone. It is used in adults and in adolescents whose bones have finished growing. This use is approved for the Xgeva brand of denosumab. Denosumab is approved to prevent and treat: Broken bones and other bone problems caused by solid tumors that have metastasized (spread) to bone. This use is approved for the Xgeva brand of denosumab. Osteoporosis in postmenopausal women who have a high risk of breaking bones. This use is approved for the Prolia brand of denosumab. Denosumab is also approved to increase bone mass in patients who are at high risk of breaking bones.
Download PDF of this page. The FDA just recently approved a new drug, denosumab (now christened with the marketed name XGEVA) as a treatment for patients with bone metastases from solid tumors such as lung cancer, breast cancer, and prostate cancer (in fact about three quarters of bone metastases are in these three cancer types).