0-2 weeks of age: These are the most difficult kittens to hand-rear and if you have successfully done this and got a healthy kitten out at six weeks of age, you can pat yourself on the back because itâs difficult, even for people who do it all the time.
Buproprion is an atypical antidepressant classified as a monocyclic aminoketone. It received FDA approval in 1984 for the treatment of depression. In 1986, buproprion was removed from the market due to an unacceptable incidence of seizures in people who took it. It was reintroduced in 1989 with a lower dosing schedule.
Antimetabolite drugs were among the first effective chemotherapeutic agents discovered and are folic acid, pyrimidine or purine analogues. They are characterized by low molecular weights. They have similar structures as naturally occurring molecules used in nucleic acid (DNA and RNA) synthesis. Antimetabolites are similar to chemicals needed for normal biochemical activity, but differ enough so that they interfere with normal cell function. Generally, antimetabolites induce cell death during the S phase of cell growth when incorporated into RNA and DNA or inhibit enzymes needed for nucleic acid production. These agents are used for a variety of cancer therapies including leukemia, breast, ovarian and gastro-intestinal cancers.