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Renal tubular acidosis, a kidney condition that makes the urine more acidic. Kidney stones form more easily in acidic urine. ... Uric acid, calcium oxalate, and cystine stones form more readily in acidic urine, so this prevention strategy hinges on keeping the urine slightly alkaline.
The leading cause of kidney stones is a lack of water. Stones commonly have been found in those that drink less than the recommended eight to ten glasses of water a day. When there is not enough water to dilute the uric acid (component of urine), the pH level within the kidneys drops and becomes more acidic. An excessively acidic environment in the kidneys is conducive to the formation of kidney stones. Medical conditions such as Crohn's disease, urinary tract infections, renal tubular acidosis, hyperparathyroidism, medullary sponge kidney, and Dent's disease have been known to lead to kidney stones.