Surfactant is a complex substance containing phospholipids and a number of apoproteins. This essential fluid is produced by the Type II alveolar cells, and lines the alveoli and smallest bronchioles.
William and Anne Shakespeare had three children. Their first child was Susanna, born a mere six months after the wedding of her parents. She was christened on May 26, 1583, and twins arrived in January, 1585.
In 1585, Anne bore twins, baptized Hamnet and Judith Shakespeare. Hamnet died at the age of eleven, by which time William Shakespeare was already a successful playwright. Around 1589, Shakespeare wrote Henry VI, Part 1, which is considered to be his first play.