The geography of La Primavera is predominantly flat as part of the Orinoquia region in the Llanos plains. The region is crossed by numerous rivers affluents of the Meta River basin. The municipality has a total area of 98,970 kmÂ² and the seat of the municipality covers an area of 54,789 kmÂ².
Drugs versus Biologics. 1  A biologic is manufactured in a living system such as a microorganism, or plant or animal cells. 2  Most biologics are very large, complex molecules or mixtures of molecules.enerics Drugs versus Follow-On Biologics. 1  To be approved as a generic, a drug must have the same active ingredient, strength, dosage form, and route of administration as the reference drug, and it must also be bioequivalent..
Virtually all drugs carry possible side effects. Biologics for the treatment of RA are no different. As seen above, biologics work in a number of different ways to reduce inflammation. They all interfere with some aspect of immune system function, though.For this reason, people taking a biologic drug may be at greater risk for certain infections.hese modern âbiologicsâ have greatly improved the effectiveness of treatment for many RA patients. Unlike older disease-modifying anti-rheumatic drugs (DMARDs), biologic DMARDs are made using biotechnology. They are genetically engineered to behave like natural immune system proteins.