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Drugs can cause a pupil to change in two ways by dilation making the pupil larger or constricting the pupils.â¦ Only two drugs constrict the pupils those being opiates and alcohol. So anything but, these can cause the pupils to dilate.
The symptoms vary depending on the exact cause of pinpoint pupils. What are the causes of pinpoint pupils? Overdose of opioid drug/opioid poisoning. one of the possible causes of constricted pupils in adults is excessive intake of opioids. In fact, it is one of the diagnostic criteria for opioid overdose. What kind of drugs cause pinpoint pupils?