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Drugs can cause a pupil to change in two ways by dilation making the pupil larger or constricting the pupils.â¦ Only two drugs constrict the pupils those being opiates and alcohol. So anything but, these can cause the pupils to dilate.
Best Answer: Ecstasy, amphetamines, cocaine, crack, meth, all dilate the eyes, to look like little totally black eyes and harderly no colour. heroin makes the pupils look like pin dots. Alcohol can dilate the eyes also if drank to excess. All these drugs can make the pupils dilate till the next evening.hat drugs cause the pupil to dilate...and how long do the pupils stay dilated after last usage? She came home after being out all night for New Year&#39;s Eve...I was out when she got home and when I returned at 2 p.m. she was sleeping on the couch..she slept all day...and when she finally got...