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Just when it is time to unwind and give the legs a much-needed break, leg pain at night can ruin any plans for rest. Night leg pain is so common that it is difficult to meet a person who has not experienced total sleep disruption as a result. Men, women and children have experienced this phenomenon. The causes of night leg pain might be from restless leg syndrome, nocturnal leg cramps or growing pains. Video of the Day
1 Worsening of symptoms in the evening. 2  Symptoms occur mainly at night. 3  Nighttime leg twitching. 4  RLS/WED may be associated with another, more common condition called periodic limb movement of sleep, which causes your legs to twitch and kick, possibly throughout the night, while you sleep.