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What are quinolones? Quinolones are antimicrobial agents effective in the treatment of selected community-acquired and nosocomial infections. They are usually administered orally, but some can be given intravenously for treatment of serious infections. Quinolones are bactericidal and exhibit concentration-dependent killing.
The prevalence of quinolone resistance in N. gonorrhoeae is well documented. (12-14) As a result experts no longer recommend the use of quinolones for the treatment of gonococcal infections and associated conditions such as pelvic inflammatory disease (PID). (11).norectal infections may cause pruritus, tenesmus, and discharge. Conjunctivitis may occur in adults, however, this infection is more prevalent in newborns and may cause blindness if not treated adequately. Bacteremia is rare, occurring in only 0.5 â 1% of gonorrheal infections.