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The epidermis contains no blood vessels, and is nourished by diffusion from the dermis. The main type of cells which make up the epidermis are keratinocytes, melanocytes, Langerhans cells and Merkels cells. The epidermis helps the skin to regulate body temperature.
So far, scientists have identified several different types of skin stem cell: 1  Epidermal stem cells are responsible for everyday regeneration of the different layers of the epidermis. 2  These stem cells are found in the basal layer of the epidermis.3  Hair follicle stem cells ensure constant renewal of the hair follicles.kin stem cells. In everyday life your skin has to cope with a lot of wear and tear. For example, it is exposed to chemicals like soap and to physical stresses such as friction with your clothes or exposure to sunlight.