NSAIDs work by reducing the production of prostaglandins, chemicals that cause pain, fever and inflammation. NSAIDs block the enzyme that makes prostaglandins (cyclooxygenase), resulting in lower production of prostaglandins. As a consequence, inflammation, pain and fever are reduced.
Medical Definition of BILIRUBIN. : a reddish yellow pigment C33H36N4O6 that occurs especially in bile and blood and causes jaundice if accumulated in excess.
Bilirubin is one of the substances produced in the liver which is released in the bile. Bilirubin is a yellow colored pigment that is responsible for the yellow color that we see in the urine. High bilirubin in adults is the characteristic of a condition known as jaundice.