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The average half-life of Xanax, which means the time it takes the blood to eliminate half of the drug is 11.2 hours (with a range of 6.3 to 26.9 hours). Xanax XR is an extended release version of the drug.
A single 0.5 mg dose of Xanax stays in your system for 3 to 5 days. But the longer period of taking Xanax, and the higher the dosages, the longer it will take your system to get rid of traces of Xanax.