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In addition, these horses are occasionally treated with nonsteroidal anti-inflammatory drugs to control musculoskeletal discomfort, which can add to gastric ulcer formation. Equine gastric ulcer syndrome (EGUS) diagnosis and treatment is frustrating for the horse owner and the veterinarian.
Ulcers that do not heal with treatment may indicate a resistant form of H. pylori or the presence of other factors interfering with the healing process like smoking, alcohol or NSAID use. Rare causes of ulcers include extreme overproduction of stomach acid (Zollinger-Ellison syndrome), stomach cancer, or Crohnâs disease.