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Drugs can cause a pupil to change in two ways by dilation making the pupil larger or constricting the pupils.â¦ Only two drugs constrict the pupils those being opiates and alcohol. So anything but, these can cause the pupils to dilate.
Pupils constrict when an object is brought closer to the eyes, to help them focus properly on it. Also pupils constrict when hit by light, the brighter the light, the bigger tâ¦he constriction. If an equal amount of light shines into both eyes, the degree of constriction is generally equal.