In the open-label trial of out- and in-patients with depression who had not responded to adequate monotherapy with two antidepressants, the addition of mirtazapine (15â30 mg/day) to either an SSRI (n= 23) or venlafaxine (n= 12) led to remission in half of the patients.
Other, rare causes of discolored nails include the yellow nail syndrome, an inherited condition that results in slow-growing, yellowing, discolored nails and is associated with lymphedema (swelling of tissues due to the accumulation of fluid) and lung diseases.ails may also appear lightened to a whitish-yellow color if there has been separation of the nail from the nail bed, termed onycholysis. The skin, mucous membranes, and nails may appear blue when there is inadequate oxygenation of blood (cyanosis), but this is not true discoloration of the nail itself.
In case your nails are affected by a fingernail fungus called Tricophyton rubrum, they might emit an unpleasant odor. Discoloration and damage to the nail bed can also be caused by a bacterium called Pseudomonas. This bacterial infection causes the color of the fingernails to turn green.he color of the nails turns yellow or yellowish-green. The nails grow at a very slow rate. Sometimes, the nails could also separate from the nail bed. Sinusitis, pleural effusions, and lymphedema are some of the medical conditions that are associated with yellow nail syndrome.