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A: The enzymes that break down protein include trypsin, chymotrypsin, pepsin, thermolysin, glutamyl endopeptidase, elastase, bromelain and papain. Trypsin, pepsin, elastase, thermolysin, glutamyl, endopeptidase and chymotrypsin are made in the human body. Bromelain comes from pineapples and papain comes from papayas.
Add a new page. Enzymes are large globular protein molecules â meaning they are made of large chains of amino acids, which have been folded into a specific shape; their effective functioning is dependent on their shape. A substrate is the molecule on which an enzyme acts.