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The average half-life of Xanax, which means the time it takes the blood to eliminate half of the drug is 11.2 hours (with a range of 6.3 to 26.9 hours). Xanax XR is an extended release version of the drug.
Best Answer: Xanax half life: how long does Xanax stay in your system. On average, experts define the half life of Xanax at 12 hours. But Xanax half-life can be anywhere from 6-20 hours.