The Atlantic trade was in trouble because of the depredations of the English and Dutch. Catalonia was a self-governing province, ruled by a viceroy, that had been part of the Crown of Aragon since the Middle Ages. It was difficult to govern and in the reign of Philip II order had broken down almost completely.
Diabetics or others with nerve damage in the feet are also susceptible to toe cramp problems. Some medications may cause cramps in the toes as a side effect. Another possible cause of is a lack of minerals, such as calcium and potassium, in the body. Dehydration is another body problem that could cause cramping toes.
Muscle Cramping (Hemodialysis) Muscle cramping of the hands, feet, and legs is fairly common on hemodialysis. The cause of muscle cramping is unknown. However, three conditions that seem to increase cramping are: 1) hypotension; 2) the patient being below dry weight; and 3) use of low sodium dialysis solution. Muscle cramps are more commonly associated with low blood pressure.