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Vicodin contains hydrocodone and acetaminophen. Fioricet contains acetaminophen, butalbital, and caffeine. I would be cautious in using both products, in order to prevent overdosing of acetaminophen. This medication, while safe as an over-the-counter medication, can cause damage to the liver at extreme doses.
Thanks for your time, Tracy. Answer: Vicodin ES is 7.5 hydrocodone and 750 mg acetaminophen, Vicodin 7.5 is 7.5 hydrocodone and 500 mg acetaminophen. The toxis dosage per day of acetaminophen is 10 gm but, most would not recommend taking more than 4-5 gms a day.nswer: Vicodin is limited by the acetaminophen aspect of the drug. Too much a day has liver toxicity. However, every 4 hours is probably ok. But, you might raise some of the long acting narcotics(MS Contin, Oxy Contin) etc. or the narcotic patches(fentanyl) as a base for the pain and taking Vicodin for breakthrough.