This explains why this idiom is associated with various types of risk taking, including risk by assuming something without all the facts or by trying to help another person at oneâs own possible detriment. This expression was first used by as early as the late 1800s. Examples of To Go Out On a Limb
In elderly individuals, amyloid protein deposits along the blood vessels can cause the vessel wall to weaken leading to a hemorrhagic stroke. Cocaine or drug abuse can weaken blood vessels and lead to bleeding in the brain. Some prescription drugs can also increase the risk of brain hemorrhage.
1 Head trauma . Injury is the most common cause of bleeding in the brain for those younger than age 50.  High blood pressure . This chronic condition can, over a long period of time, weaken blood vessel walls.