What do mast cells and basophils release? Granules that contain substances such as histamine (stimulates vasodilation and increases capillary permeability), heparin (anticoagulant) and eicosanoids (increases inflammation due to release from the plasma membrane).
Orange Is the New Black is better than ever in Season 4. Sophia. Where we left off: After Gloria (Selenis Leyva) blamed Sophia's (Laverne Cox) son for being a bad influence on hers, their friendship turned sour, leading Aleida (Elizabeth Rodriguez) to spread cruel and transphobic rumors about Sophia.
Things don't really take a turn for the dark until the season's final hours, with a heartbreaking twist that will stick with viewers long past when their binge-watch is done. In Season 4, Orange Is the New Black once again epitomizes the concept of binge-watching. It's the type of compelling TV that leaves you barreling through the individual episodes, while at the same time not wanting the season to end.