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Wilson disease is a rare inherited disorder. If both parents carry an abnormal gene for Wilson disease, there is a 25% chance in each pregnancy that the child will have the disorder.Wilson disease causes the body to take in and keep too much copper. The copper deposits in the liver, brain, kidneys, and eyes.auses. Wilson disease is a rare inherited disorder. If both parents carry an abnormal gene for Wilson disease, there is a 25% chance in each pregnancy that the child will have the disorder. Wilson disease causes the body to take in and keep too much copper.
Summary. Wilson's disease (WD) is an inborn error of copper metabolism caused by a mutation to the copper-transporting gene ATP7B. The disease has an autosomal recessive mode of inheritance, and is characterized by excessive copper deposition, predominantly in the liver and brain.