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The narcotic in both medications is the oxycodone, the only difference between the two is the additiâ¦on of Tylenol (aka acetaminophen). The addition of Tylenol does not necessarily make the combo drug more powerful than the straight oxycodone, but is an adjunctive therapy so to speak.
Oxycodone/Apap 7.5mg/325mg contains two medications, oxycodone at a dose of 7.5mg and acetaminophen (Tylenol) at a dose of 325mg. Oxycodone (OxyIR) is an opioid analgesic used to treat moderate to severe pain. Oxycodone 5mg contains one medication; oxycodone at a dose of 5mg.Oxycodone/APAP 7.5mg/325mg has a higher oxycodone dose than oxycodone 5mg and it contains an additional medication, acetaminophen.: Oxycodone is a narcotic pain reliever that is used to treat moderate to severe pain. This medication has a half-life of between 3 and 4.5 hours. This means that half of the dosage is eliminated from the body after 4 hours, and for each consecutive 4 hours another half of what is left over will be eliminated.