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The epidermis contains no blood vessels, and is nourished by diffusion from the dermis. The main type of cells which make up the epidermis are keratinocytes, melanocytes, Langerhans cells and Merkels cells. The epidermis helps the skin to regulate body temperature.
There are 3 main types of cells in the top layer of the skin (called the epidermis): 1  Squamous cells: These are flat cells in the outer part of the epidermis that are constantly shed as new ones form. 2  Basal cells: These cells are in the lower part of the epidermis, called the basal cell layer. These cells constantly divide to form new cells to replace the squamous cells that wear off the skinâs surface.