The geography of La Primavera is predominantly flat as part of the Orinoquia region in the Llanos plains. The region is crossed by numerous rivers affluents of the Meta River basin. The municipality has a total area of 98,970 kmÂ² and the seat of the municipality covers an area of 54,789 kmÂ².
Drugs versus Biologics. 1  A biologic is manufactured in a living system such as a microorganism, or plant or animal cells. 2  Most biologics are very large, complex molecules or mixtures of molecules.enerics Drugs versus Follow-On Biologics. 1  To be approved as a generic, a drug must have the same active ingredient, strength, dosage form, and route of administration as the reference drug, and it must also be bioequivalent..
Biologics (or biopharmaceuticals) are a class of drugs based on proteins that have a therapeutic effect. These large protein molecules â which are composed of more than 1,300 amino acids and can be as heavy as 150,000 g/mol (or 150 kDa) â are essentially copies or optimized versions of endogenous human proteins.