Its competitor, Otrexup, costs $500 to $600 a month for a 25 mg dose â more than a vial of methotrexate and far more than pills, which cost $20 to $30 for a dozen 2.5 mg tablets.
The leaders of Britain, France, Italy, and Germany held a conference in Munich, Germany, on September 29-30, 1938, in which they agreed to the German annexation of the Sudetenland in exchange for a pledge of peace from Hitler. Czechoslovakia, which was not a party to the Munich negotiations, agreed under significant pressure from Britain and France. On March 15, 1939, Hitler violated the Munich agreement and moved against the Czechoslovak state. The Czech provinces of Bohemia and Moravia were proclaimed a German protectorate and were occupied by German forces. Slovakia became an independent state, closely allied with Germany.
The agreement was negotiated at a conference held in Munich, Germany, among the major powers of Europe, excluding the Soviet Union and Czechoslovakia.Today, it is widely regarded as a failed act of appeasement toward Germany.ecause the state of Czechoslovakia was not invited to the conference, it considered itself to have been betrayed by the United Kingdom and France, so Czechs and Slovaks call the Munich Agreement the Munich Diktat (Czech: MnichovskÃ½ diktat; DiktÃ¡t: Slovak mnichovskÃ½). mnÃ­chovskÃ½ diktat diktÃ¡t