Elizabeth I dies and James VI of Scotland accedes to the English throne. Elizabeth I died childless so was succeeded by her cousin, James VI of Scotland, who henceforth assumed the title of James I of England as well.
T minus zero means out of time.. This comes from a countdown convention used in by both the American military and NASA. Generally, it is used when counting down to a major event that will happen at a specific time. Mathematically, T is time, minus whatever amount of time is left until the event happens.
What does the medical abbreviation T PO BID mean? It's likely that the T you're reading is actually the prescription stylized way of writing the number 1. In that case, it's read 1 po bid, and means one by mouth daily.