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Drugs can cause a pupil to change in two ways by dilation making the pupil larger or constricting the pupils.â¦ Only two drugs constrict the pupils those being opiates and alcohol. So anything but, these can cause the pupils to dilate.
1 Pupil constriction and Head symptoms (2 causes) 2  Pupil constriction and Miosis (2 causes) 3  Pupil constriction and Pupillary constriction (2 causes)  Pupil constriction and Pupillary constriction in both eyes (2 causes)