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The narcotic in both medications is the oxycodone, the only difference between the two is the additiâ¦on of Tylenol (aka acetaminophen). The addition of Tylenol does not necessarily make the combo drug more powerful than the straight oxycodone, but is an adjunctive therapy so to speak.
Oxycodone may be thought of as the lesser of the two evils because it is often combined with other medications. It is still an opiate but may be combined with ibuprofen or Tylenol in some formulations. A number of prescription pain relievers including Percocet, Percodan, Tylox and OxyContin all contain oxycodone. However, oxycodone is the only ingredient in the stronger version of the drug: OxyContin.