Under a franchise arrangement, a person or company purchases the ability to run a local business under a larger company's brand. Depending on the franchise arrangement, the local party may have to meet certain standards established by the larger company and purchase products from the larger company as well.
Half-cock is when the position of the hammer is partially but not completely cocked.
Table 1. Glossary of terms. Term Definition. Cohort Group of patients treated at a dose level. Starting dose The dose chosen to treat the first cohort of patients in a phase I trial. Dose increment (decrement) The percent increase (or decrease) between dose levels. Dose-limiting toxicity (DLT) Toxic effects that are presumably related to the drugs that are considered unacceptable (because. of their severity and/or irreversibility) and that limit further dose escalation.