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Overview. Inflammatory bowel disease (IBD) is not a single condition. It is the term for a group of disorders that cause prolonged inflammation of the digestive tract.The digestive tract is composed of the mouth, esophagus, stomach, small intestine, and large intestine.he two most common are ulcerative colitis and Crohnâs disease. Crohnâs disease can cause inflammation in any part of the digestive tract. However, it mostly affects the tail end of the small intestine. Ulcerative colitis is inflammation of the large intestine.
1 Intestinal inflammation in Crohn's disease involves the entire thickness of the bowel wall, whereas the inflammation in ulcerative colitis is confined to the inner lining. 2  Accordingly, complications such as intestinal strictures, fistulas, and fissures are far more common in Crohn's disease than in ulcerative colitis.