This explains why this idiom is associated with various types of risk taking, including risk by assuming something without all the facts or by trying to help another person at oneâs own possible detriment. This expression was first used by as early as the late 1800s. Examples of To Go Out On a Limb
In elderly individuals, amyloid protein deposits along the blood vessels can cause the vessel wall to weaken leading to a hemorrhagic stroke. Cocaine or drug abuse can weaken blood vessels and lead to bleeding in the brain. Some prescription drugs can also increase the risk of brain hemorrhage.
A brain hemorrhage, one of the two main types of stroke results when a ruptured artery causes bleeding into the brain (intracerebral bleed) or into the space between the membranes surrounding the brain (subarachnoid hemorrhage). Blood vessel abnormalities such as arteriovenous malformation (AVM) may result in a stroke. 2  A head injury may rupture arteries in the brain. 3  Brain tumors may lead to intracerebral bleeding. 4  An increasingly recognized cause of brain hemorrhage in the elderly is amyloid angiopathy.