Perinatal hypoxia can lead to a number of serious medical conditions, such as Hypoxic Ischemic Encephalopathy (HIE) and brain injuries related to birth asphyxia. All three of these injuries are serious brain injuries that may lead to paralysis and severe brain damage.
1 A substance (or ligand) is cholinergic if it is capable of producing, altering, or releasing acetylcholine (indirect-acting) or mimicking its behaviour at one or more of the body's acetylcholine receptor types (direct-acting).2  Such mimics are called parasympathomimetic drugs or cholinomimetic drugs.n general, the word choline refers to the various quaternary ammonium salts containing the N,N,N-trimethylethanolammonium cation. Found in most animal tissues, choline is a primary component of the neurotransmitter acetylcholine and functions with inositol as a basic constituent of lecithin.
For instance their is a cholinergic drug called Pilocarpine which is used to decrease intraocular pressure. Some of the effects of cholinergics are decreased blood pressure, heart rate, increased urination and gastric emptying (which would give you the diarrhea). In order for drugs to produce their action they often need to go through systemic circulation in order to act on their destined receptor sites.