Perinatal hypoxia can lead to a number of serious medical conditions, such as Hypoxic Ischemic Encephalopathy (HIE) and brain injuries related to birth asphyxia. All three of these injuries are serious brain injuries that may lead to paralysis and severe brain damage.
1 A substance (or ligand) is cholinergic if it is capable of producing, altering, or releasing acetylcholine (indirect-acting) or mimicking its behaviour at one or more of the body's acetylcholine receptor types (direct-acting).2  Such mimics are called parasympathomimetic drugs or cholinomimetic drugs.n general, the word choline refers to the various quaternary ammonium salts containing the N,N,N-trimethylethanolammonium cation. Found in most animal tissues, choline is a primary component of the neurotransmitter acetylcholine and functions with inositol as a basic constituent of lecithin.
Precautions. Cholinergic drugs should be avoided when the patient has any sort of obstruction in the urinary or digestive tracts, such a a tumor, or severe inflammation which is causing blockage. They should be used with caution in patients with asthma, epilepsy, slow heart beat, hyperthyroidism, or gastric ulcers.The effects of the cholinergic drugs are to produce the same effects as stimulation of the parasympathetic nervous system.These effects include slowing of the heartbeat, increases in normal secretions including the digestive acids of the stomach, saliva and tears.hey should be used with caution in patients with asthma, epilepsy, slow heart beat, hyperthyroidism, or gastric ulcers. The effects of the cholinergic drugs are to produce the same effects as stimulation of the parasympathetic nervous system.