Perinatal hypoxia can lead to a number of serious medical conditions, such as Hypoxic Ischemic Encephalopathy (HIE) and brain injuries related to birth asphyxia. All three of these injuries are serious brain injuries that may lead to paralysis and severe brain damage.
1 A substance (or ligand) is cholinergic if it is capable of producing, altering, or releasing acetylcholine (indirect-acting) or mimicking its behaviour at one or more of the body's acetylcholine receptor types (direct-acting).2  Such mimics are called parasympathomimetic drugs or cholinomimetic drugs.n general, the word choline refers to the various quaternary ammonium salts containing the N,N,N-trimethylethanolammonium cation. Found in most animal tissues, choline is a primary component of the neurotransmitter acetylcholine and functions with inositol as a basic constituent of lecithin.
An article in your April issue, Common drugs linked to dementia, states that anticholinergics are used to treat depression. I wasn't aware of this. Which types of anticholinergics are used for depression? A. We should have been clearer in our description of the medications. Anticholinergic drugs work by blocking the effects of acetylcholine, a substance that transmits messages in the nervous system. In the brain, acetylcholine is involved in learning and memory. In the rest of the body, it stimulates muscle contractions. A wide range of drugsâincluding tricyclic antidepressants like amitriptyline (Elavil) or doxepin (Deptran, Silenor, Sinequan)âhave strong anticholinergic effects, which means they can have side effects like memory problems and confusion.