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Buspirone is a medication used to treat anxiety. Unfortunately, eating a grapefruit while taking buspirone can decrease its effectiveness. MedlinePlus says that buspirone's side effects include vomiting, constipation, trouble breathing, fatigue, nervousness, weakness, numbness, dry mouth and stomach problems.
Certain pain medications: methadone; The impotence drug (erectile dysfunction): sildenafil (Viagra) Some HIV medication: saquinavir ; Some antiarrhythmics: amiodarone (Cordarone, Pacerone) There are alternatives to many of these drugs. So, talk to your doctor about the possibility of using a different medication if avoiding grapefruit juice is not an option.