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Ganglion Cyst Quick Overview. A ganglion cyst is a tumor or swelling (benign, not cancerous) usually on top of a joint or the covering of a tendon (tissue that connects muscle to bone). It looks like a sac of liquid (cyst) located just under the skin. Inside the cyst is a thick, sticky, clear, colorless, jellylike material.
A ganglion is also a collection of nerve cell bodies located outside the central nervous system. This article refers only to fluid-like swellings that form on top of joints, tendons in the wrists, hands and feet (ganglion cysts).Women are more likely than men to develop ganglion cysts.anglion cysts often do not require treatments, as they will rupture and disappear on their own. However, it is possible to use a syringe to remove the fluid (aspiration) or resect the entire ganglion in a surgical procedure.