Two amino acid mutations in MTHFR, the C677T and the A1298C mutations, contribute to the potential for accumulation of homocysteine. The risks for elevated homocysteine are predominantly with the homozygous (two copies) state of each of these mutations, with the A1298 overall being less severe than the C677T mutation.
Necrotizing enterocolitis, usually called NEC, is a condition where the intestines become infected and can begin to die. The disease usually affects premature babies, although term babies may also get NEC. Necrotizing enterocolitis is a serious condition that may require surgery, and has a high morbidity and mortality rate.
The colon is the symbol :. It is used in a number of different ways in mathematics. 1. To denote ratio or odds, as in 2:1 (voiced two to one). 2. To mean such that in constructions such as (voiced the set of numbers such that ). 3. To give a name to a map, e.g., (which is equivalent to the function notation ).