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Buspirone is a medication used to treat anxiety. Unfortunately, eating a grapefruit while taking buspirone can decrease its effectiveness. MedlinePlus says that buspirone's side effects include vomiting, constipation, trouble breathing, fatigue, nervousness, weakness, numbness, dry mouth and stomach problems.
Although an interaction is possible, it is usually okay to drink grapefruit juice or eat grapefruits while taking Fosamprenavir. In theory, side effects from Fosamprenavir such as diarrhea, headache, or rash might get worse if you drink grapefruit juice or eat grapefruits, but significant interactions have not been reported. Do not greatly alter your normal grapefruit and grapefruit juice intake while taking Fosamprenavir.