Blood is mostly made up of water, as are our organs and muscles. To read specifically about edema, swelling caused by fluid retention where excess fluid is trapped in the body's tissues, see our article Edema: Causes, Symptoms and Treatments.
If you use the Amsoil Ea15K01 and the ASM oil (For 3rd gen Prius), then you can safely go 15,000 miles between oil changes. I drive 25,000 miles per year in my Prius. Amsoil backs up their products by a written warranty.
Who the Fuck changes oil on a Honda every 10k miles. If your wanting your engine to last less than 100k miles, do that. As an ASE certified tech, I reccomend if your using standard motor oil, change every 3000-3500 miles. If your using partial synthetic, do every 5000 miles.