High anion gap metabolic acidosis. High anion gap metabolic acidosis is a form of metabolic acidosis characterized by a high anion gap (a medical value based on the concentrations of ions in a patient's serum). An anion gap is usually considered to be high if it is over 11 mEq/L.
Leukemia (American English) or leukaemia (British English) is a group of cancers that usually begin in the bone marrow and result in high numbers of abnormal white blood cells. These white blood cells are not fully developed and are called blasts or leukemia cells.he exact cause of leukemia is unknown. Different kinds of leukemia are believed to have different causes. Both inherited and environmental (non-inherited) factors are believed to be involved. Risk factors include smoking, ionizing radiation, some chemicals (such as benzene), prior chemotherapy, and Down syndrome.
1 Certain genetic disorders, such as Down syndrome, are associated with an increased risk of leukemia. 2  Exposure to certain chemicals. 3  Exposure to certain chemicals, such as benzene â which is found in gasoline and is used by the chemical industry â also is linked to an increased risk of some kinds of leukemia. 4  Smoking. Previous cancer treatment. 2  People who've had certain types of chemotherapy and radiation therapy for other cancers have an increased risk of developing certain types of leukemia. 3  Genetic disorders. 4  Genetic abnormalities seem to play a role in the development of leukemia.