Macadamia is a genus of four species of trees indigenous to Australia and constituting part of the plant family Proteaceae.They are native to north eastern New South Wales and central and south eastern Queensland.he species previously named in this Macadamia genus may still be referred to overall by the descriptive, non-scientific name of macadamia; their disjunct distributions and current scientific names are: 1  New Caledonia endemic genus Virotia in 1975 having only the type species, then by 2008 all six endemic species.
Hereditary sensory and autonomic neuropathy (HSAN) or hereditary sensory neuropathy (HSN) is a condition used to describe any of the types of this disease which inhibit sensation.enes related to Hereditary sensory and autonomic neuropathy Type 3 : Mutations in the IKBKAP gene cause familial dysautonomia. The IKBKAP gene provides instructions for making a protein called IKK complex-associated protein (IKAP). This protein is found in a variety of cells throughout the body, including brain cells.
Clinical characteristics. Congenital insensitivity to pain with anhidrosis (CIPA), also known as hereditary sensory and autonomic neuropathy type IV (HSAN IV), is characterized by insensitivity to pain, anhidrosis (the inability to sweat), and intellectual disability.ereditary sensory and autonomic neuropathies (HSANs). Congenital insensitivity to pain with anhidrosis (CIPA; also known as hereditary sensory and autonomic neuropathy type IV (HSAN IV) belongs to the family of hereditary sensory and autonomic neuropathies (HSANs).