These studies illustrate that the normal urination of asymptomatic people varies widely with fluid intake, age, gender, and race. Nevertheless, the fact that 95% of femal and male subjects respectively voided fewer than 13 times and 12 times is applicable to this answering.
1 Medical causes â unrelenting exhaustion may be a sign of an underlying illness, such as a thyroid disorder, heart disease or diabetes. 2  Lifestyle-related causes â alcohol or drugs or lack of regular exercise can lead to feelings of fatigue.  Workplace-related causes â workplace stress can lead to feelings of fatigue.
Other medical causes of fatigue are the side effect of drugs, thyroid dysfunction, high calcium levels, rheumatologic illnesses, adrenal, kidney or liver problems. Some infections such as tuberculosis or hepatitis can cause fatigue, and indeed, fatigue can be their only symptom. Depression is also a major cause of fatigue. While unusual, uncontrolled diabetes can be the cause of fatigue. These patients generally also have other symptoms of diabetes such as excess thirst, frequent urination and blurred vision. Some drugs used to treat diabetes can cause fatigue by causing anemia or a metabolic change known as lactic acidosis.