Patients were stratified according to tumor PD-L1 status assessed in a central laboratory by immunohistochemical testing (positive vs. negative or indeterminate), BRAF mutation status (V600 mutation-positive vs. wild-type) and American Joint Committee on Cancer stage.[Level of evidence: 1iiA]
Swallowing air excessively; Gastroesophageal reflux; Hiatus hernia; Rapid eating; Intense emotions such as fear, anxiety, excitement, joy, or euphoria [citation needed] Carbonated beverages, alcohol, dry breads, and some spicy foods; Opiate drug use; Laughing; Hiccups may be triggered by a number of common human conditions.
Causes. 1  Causes of bloating include swallowing air. 2  Swallowed air is usually burped up, but if not the air passes through your digestive system and releases as flatus. 3  You may find that excessive air swallowing also causes hiccups. 4  Foods and beverages can cause bloating. 5  The amount and type varies from person to person.