Two amino acid mutations in MTHFR, the C677T and the A1298C mutations, contribute to the potential for accumulation of homocysteine. The risks for elevated homocysteine are predominantly with the homozygous (two copies) state of each of these mutations, with the A1298 overall being less severe than the C677T mutation.
Necrotizing enterocolitis, usually called NEC, is a condition where the intestines become infected and can begin to die. The disease usually affects premature babies, although term babies may also get NEC. Necrotizing enterocolitis is a serious condition that may require surgery, and has a high morbidity and mortality rate.
An ileostomy (also known as a small intestine stoma)= an artificial opening of the small intestine (ileum). An ileostomy is formed when the large intestine (and possibly the rectum) no longer function or have been removed. The lower end of the small intestine is then pulled through and stitched to the abdomen. urostomy (also known as a urine stoma) = an artificial opening of the urinary tract. A urostomy is formed when urine can no longer leave the body naturally. In a urostomy the bladder is removed and the 2 ureters are stitched to the abdomen by using a piece of the small intestine.