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Other signs and symptoms of Prader-Willi syndrome may include: 1  Nearsightedness (myopia) and other vision problems. 2  Light skin and hair compared with other family members. 3  High pain tolerance, making it difficult to identify injury or illness. 4  Problems regulating body temperatures during fever or in hot and cold places.
However, most forms of collagen vascular disease do share some of the same general symptoms. People with collagen vascular disorders typically experience: fatigue; muscle weakness; fever; body aches; joint pain; skin rash; Symptoms of lupus. Lupus is a collagen vascular disease that causes unique symptoms in each patient. Additional symptoms can include: