(April 2014) In law and government, de jure (/deÉª ËdÊÊrÉª/; Latin: de iure, in law) describes practices that are legally recognized by official laws. In contrast, de facto (in fact or in practice) describes situations that are generally known to exist in reality, even if not legally authorized.
Only a portion of them are chromosome abnormalities. Single gene disorders are conditions that are caused by a change in a single gene. Because there are thousands of genes, there are thousands of single gene disorders. This group of disorders cannot be diagnosed by a karyotype.
A karyotype also can reveal deletions in chromosomes that are the underlying cause of conditions such as Cri-du-Chat syndrome (chromosome 5) or Williams syndrome (chromosome 7), as well as translocations in which one part of a chromosome is found on or switched with another part of a different chromosome.