Small and nonpolar (hydrophobic) molecules can freely pass through the membrane, but charged ions and large molecules such as proteins and sugars are barred passage. The selective permeability of the cell membrane allows a cell to maintain its internal composition at necessary levels.
This will be between 7AM - 11PM their time, since New York (NY) is 6 hours ahead of Hawaii (HI). If you're available any time, but you want to reach someone in New York at work, you may want to try between 3:00 AM and 11:00 AM your time. This is the best time to reach them from 9AM - 5PM during normal working hours.
If we were converting between these two time zones, there would be a two hour difference. PDT is seven hours behind Coordinated Universal Time (UTC) so it is written as UTC -7:00. EST is five hours behind UTC, written as UTC -5:00. Hereâs an example: If it is 2:15 PM in Pacific Daylight Time, then it is 4:15 PM in Eastern Standard Time. This gap widens when both zones are off of DST in the winter months. When both standard times are in effect, the difference is three hours.