Patients were stratified according to tumor PD-L1 status assessed in a central laboratory by immunohistochemical testing (positive vs. negative or indeterminate), BRAF mutation status (V600 mutation-positive vs. wild-type) and American Joint Committee on Cancer stage.[Level of evidence: 1iiA]
Swallowing air excessively; Gastroesophageal reflux; Hiatus hernia; Rapid eating; Intense emotions such as fear, anxiety, excitement, joy, or euphoria [citation needed] Carbonated beverages, alcohol, dry breads, and some spicy foods; Opiate drug use; Laughing; Hiccups may be triggered by a number of common human conditions.
Common causes of gas and bloating include: 1  Swallowed air. 2  If swallowed air is not burped up, it passes through the digestive tract and is released through the anus as flatus. 3  Excessive air swallowing may cause hiccups. 4  Foods and beverages.5  The amount of gas that different foods cause varies from person to person.ommon causes of gas and bloating include: 1  Swallowed air. 2  If swallowed air is not burped up, it passes through the digestive tract and is released through the anus as flatus. 3  Excessive air swallowing may cause hiccups. 4  Foods and beverages.