World Changes Due to the Telephone. Within 50 years of its invention, the telephone had become an indispensable tool in the United States. In the late 19th century, people raved about the telephone's positive aspects and ranted about what they anticipated would be negatives.
When you hold the ice cube for a very long time, the enzymes deactivate. Blood circulation stops. The brain initiates impulses for blood circulation. The local nerves therefore get irritated and produce a sensation of heat.
This cold sensation will last approximately three to five minutes until a burning sensation appears. The burning sensation will fade into an ache, followed by numbness. Beware that once numbing occurs, remove and discontinue the ice. Continued application following numbing may result in tissue damage.