Small and nonpolar (hydrophobic) molecules can freely pass through the membrane, but charged ions and large molecules such as proteins and sugars are barred passage. The selective permeability of the cell membrane allows a cell to maintain its internal composition at necessary levels.
This will be between 7AM - 11PM their time, since New York (NY) is 6 hours ahead of Hawaii (HI). If you're available any time, but you want to reach someone in New York at work, you may want to try between 3:00 AM and 11:00 AM your time. This is the best time to reach them from 9AM - 5PM during normal working hours.
As U.S. has different time zone, you have to specify where on U.S. you refer to. It's 12/13 hrs ahead from Eastern (New York) ,13hrs/14hrs from Central (Chicago), 14/15 hrs from Denver,Colorado (Mountain) and 15/16hrs from Los Angeles (Pacific).If from Alaska, its 16/17hrs & from Hawaii its 17/18hrs.The first one is Standard Timing and the latter one is for during Daylight Saving Hours.t's 12/13 hrs ahead from Eastern (New York) ,13hrs/14hrs from Central (Chicago), 14/15 hrs from Denver,Colorado (Mountain) and 15/16hrs from Los Angeles (Pacific). If from Alaska, its 16/17hrs & from Hawaii its 17/18hrs. The first one is Standard Timing and the latter one is for during Daylight Saving Hours.