1766 - In August, violence breaks out in New York between British soldiers and armed colonists, including Sons of Liberty members. The violence erupts as a result of the continuing refusal of New York colonists to comply with the Quartering Act.
Carvedilol is a type of beta-blocker that is used to treat high blood pressure, prevent a condition known as congestive heart failure from getting worse, and is used in people that have had a heart attack to treat a condition called left ventricular dysfunction.
Both in U.S. clinical trials in mild-to-moderate heart failure that compared COREG in daily doses up to 100 mg (n = 765) with placebo (n = 437), and in a multinational clinical trial in severe heart failure (COPERNICUS) that compared COREG in daily doses up to 50 mg (n = 1,156) with placebo (n = 1,133), discontinuation rates for adverse experiences were similar in carvedilol and placebo subjects.