(April 2014) In law and government, de jure (/deÉª ËdÊÊrÉª/; Latin: de iure, in law) describes practices that are legally recognized by official laws. In contrast, de facto (in fact or in practice) describes situations that are generally known to exist in reality, even if not legally authorized.
Only a portion of them are chromosome abnormalities. Single gene disorders are conditions that are caused by a change in a single gene. Because there are thousands of genes, there are thousands of single gene disorders. This group of disorders cannot be diagnosed by a karyotype.
A karyotype cannot show if there are very small bits of chromosomes missing (deletions) or very small extra bits of chromosomes (duplications) Small rearrangements of chromosomes cannot be detected The karyotype can not tell you information about the 30,000 genes that are found along the length of chromosomes While the karyotype can detect if a baby has a chromosome imbalance such as Down syndrome, it can not tell us how severely the baby will be affected