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Driving distance from Greenville, SC to Columbia, SC. The total driving distance from Greenville, SC to Columbia, SC is 104 miles or 167 kilometers. Your trip begins in Greenville, South Carolina. It ends in Columbia, South Carolina.
Driving distance from Greensboro, NC to Greenville, SC. The total driving distance from Greensboro, NC to Greenville, SC is 189 miles or 304 kilometers. Your trip begins in Greensboro, North Carolina. It ends in Greenville, South Carolina.