Two amino acid mutations in MTHFR, the C677T and the A1298C mutations, contribute to the potential for accumulation of homocysteine. The risks for elevated homocysteine are predominantly with the homozygous (two copies) state of each of these mutations, with the A1298 overall being less severe than the C677T mutation.
Necrotizing enterocolitis, usually called NEC, is a condition where the intestines become infected and can begin to die. The disease usually affects premature babies, although term babies may also get NEC. Necrotizing enterocolitis is a serious condition that may require surgery, and has a high morbidity and mortality rate.
Medical Definition of COLON. : the part of the large intestine that extends from the cecum to the rectum.ADVERTISEMENT.lural cola: a rhythmical unit of an utterance; specifically in Greek or Latin verse: a system or series of from two to not more than six feet having a principal accent and forming part of a line. 2.