Patients were stratified according to tumor PD-L1 status assessed in a central laboratory by immunohistochemical testing (positive vs. negative or indeterminate), BRAF mutation status (V600 mutation-positive vs. wild-type) and American Joint Committee on Cancer stage.[Level of evidence: 1iiA]
Swallowing air excessively; Gastroesophageal reflux; Hiatus hernia; Rapid eating; Intense emotions such as fear, anxiety, excitement, joy, or euphoria [citation needed] Carbonated beverages, alcohol, dry breads, and some spicy foods; Opiate drug use; Laughing; Hiccups may be triggered by a number of common human conditions.
When you eat, slow down. Eating quickly makes you swallow more air, and that can cause hiccups as well as burping. Try to slow down and enjoy the meal; you might also find that you eat less and feel less full, too. A runny nose caused by a cold or allergy can make you swallow excessive air. So an over-the-counter nasal decongestant can sometimes reduce belching as well as relieving the nasal symptoms, but should never be taken long term. Poorly fitting dentures may cause you to chew abnormally and swallow air.