These studies illustrate that the normal urination of asymptomatic people varies widely with fluid intake, age, gender, and race. Nevertheless, the fact that 95% of femal and male subjects respectively voided fewer than 13 times and 12 times is applicable to this answering.
1 Medical causes â unrelenting exhaustion may be a sign of an underlying illness, such as a thyroid disorder, heart disease or diabetes. 2  Lifestyle-related causes â alcohol or drugs or lack of regular exercise can lead to feelings of fatigue.  Workplace-related causes â workplace stress can lead to feelings of fatigue.
1 Not enough sleep or disruptions to the sleep-wake cycle (such as those that may occur with shift work or travelling to a different time zone) cause the physiological state known as fatigue.  Staying awake for 24 hours leads to a reduced hand-to-eye coordination that is similar to having a blood alcohol content of 0.1.