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These terms cannot be interchanged and have a specific meaning. Efficiency is the ability of an intervention to have effects on a specific marker in relation to a condition without it necessarily been relevant to patients. The study is done under highly controlled conditions with highly compliant participants.
Potency versus Efficacy. The term commonly used is efficacy-in other words, if two drugs occupy the same number of receptors on a tissue, and one drug elicits a greater biological response than the other drug (by its action on the receptor) then that drug has greater efficacy.otency versus Efficacy. The term commonly used is efficacy-in other words, if two drugs occupy the same number of receptors on a tissue, and one drug elicits a greater biological response than the other drug (by its action on the receptor) then that drug has greater efficacy.