A design approach is a general philosophy that may or may not include a guide for specific methods. Some are to guide the overall goal of the design. Other approaches are to guide the tendencies of the designer. A combination of approaches may be used if they don't conflict.
Bradycardia can be caused by: 1  Changes in the heart that are the result of aging. 2  Diseases that damage the heart's electrical system. These include coronary artery disease, heart attack, and infections such as endocarditis and myocarditis. 3  Conditions that can slow electrical impulses through the heart.
The pathophysiology of sinus bradycardia is dependent on the underlying cause.Commonly, sinus bradycardia is an incidental finding in otherwise healthy individuals, particularly in young adults, athletes or sleeping patients.Other causes of sinus bradycardia are related to increased vagal tone.