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Antipsychotics. Antipsychotic medicines, also known as neuroleptics, are usually recommended as the first treatment for psychosis. They work by blocking the effect of dopamine (a chemical that transmits messages in the brain). However, they're not suitable or effective for everyone, as side effects can affect people differently.
While these drugs may often cause an altered state of mind and possible psychosis, the abuse of any mind-altering drug for a long period of time and in large amounts may lead to drug-induced psychosis, the Substance Abuse and Mental Health Services Administration (SAMHSA) publishes.