Meth and the Brain. Meth releases a surge of dopamine, causing an intense rush of pleasure or prolonged sense of euphoria. Over time, meth destroys dopamine receptors, making it impossible to feel pleasure.
CAUSES OF HIGH AMMONIA. Ammonia is a normal by-product of processing nitrogen in the body, and is excreted as waste in the urine, in healthy people. However, elevated blood ammonia levels can occur when the kidneys or liver are not working properly, allowing this waste to remain in the bloodstream, which can be poisonous to your cells.
Ammonia is a product of the metabolism of proteins and other compounds, and it is required for the synthesis of essential cellular compounds. However, a 5- to 10-fold increase in ammonia in the blood induces toxic effects in most animal species, with alterations in the function of the central nervous system. Both acute and chronic hyperammonemia result in alterations of the neurotransmitter system.