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Polycystic kidney disease symptoms may include: 1  High blood pressure. 2  Back or side pain. 3  Headache. 4  Increase in the size of your abdomen.5  Blood in your urine. 6  Frequent urination. 7  Kidney stones.8  Kidney failure.9  Urinary tract or kidney infections.olycystic kidney disease symptoms may include: 1  High blood pressure. 2  Back or side pain. 3  Headache. 4  Increase in the size of your abdomen. 5  Blood in your urine. 6  Frequent urination. 7  Kidney stones. 8  Kidney failure. 9  Urinary tract or kidney infections.
Polycystic kidney disease: A genetic disorder characterized by the development of innumerable cysts in the kidneys. These cysts are filled with fluid, and replace much of the mass of the kidneys which reduces kidney function, leading to kidney failure.olycystic kidney disease: A genetic disorder characterized by the development of innumerable cysts in the kidneys. These cysts are filled with fluid, and replace much of the mass of the kidneys which reduces kidney function, leading to kidney failure.