Peripheral neuropathy affects the nerves in your toes, feet, legs, hands, and arms. Peripheral neuropathy may also cause muscle weakness and loss of reflexes, especially at the ankle, leading to changes in the way a person walks. Foot deformities, such as hammertoes and the collapse of the midfoot, may occur.
Your blood is pumped around by the heart which is the main function in your circulatory system. The heart sends blood through your blood vessels. The circulatory system consists of the heart, blood vessels, lymph, blood, and the lymphatic vessels and glands.
Three sets of vessels comprise the circulatory system: arteries, lymphatics, and veins. Arteries bring oxygen-carrying blood from the heart to the tissues. In the normal course of blood circulation, small amounts of fluid and protein leak from arteries and veins. Lymphatic vessels bring this protein-rich fluid back into the circulation. The third type of blood vessel is the vein. Veins bring oxygen-depleted blood from the organs and tissues to the heart and lungs, where it is re-oxygenated. Blood return to the heart tends to be passive and is enabled by muscle contraction in the arms and legs.