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Connatal Pelizaeus-Merzbacher disease is the more severe of the two types. Symptoms can begin in infancy and include problems feeding, a whistling sound when breathing, progressive spasticity leading to joint deformities (contractures) that restrict movement, speech difficulties (dysarthria), ataxia, and seizures.
It's not surprising your PMS symptoms are getting worse as you get older. This often happens, particularly with the more severe form of PMS called PMDD, or premenstrual dysphoric disorder. If you think of PMS as a continuum, at the far left is mild PMSâbloating, headaches, some irritability, maybe some other symptoms.