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Antipsychotics. Antipsychotic medicines, also known as neuroleptics, are usually recommended as the first treatment for psychosis. They work by blocking the effect of dopamine (a chemical that transmits messages in the brain). However, they're not suitable or effective for everyone, as side effects can affect people differently.
Psychosis occurs in a number of serious mental illnesses and not just schizophrenia, eg depression, bipolar disorder (manic-depressive illness), puerperal psychosis and sometimes with drug and alcohol abuse. It can also occur in a number of neurological conditions and with drugs not associated with abuse.Psychosis interferes with the ability to function and can be very debilitating. Disabling symptoms include delusions and hallucinations 1  : A delusion is a false, fixed, strange, or irrational belief that is firmly held. Depression can cause psychosis and all forms of mental illness have a risk of suicide, not just depression. 2  There are a number of forms of self-harm assessment.