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Certain neurons can repair themselves while others can't. Neurons that can repair themselves are refreed to as white matter. The reason white matter can repair itself is because the axons of white matter are myelinated.
Any cerebral cortex neurons that die are not replaced. Fat cells are replaced at the rate of about 10% per year in adults. So you could say that on average, human beings replace all their fat cells about every ten years. Cardiomyocyte heart cells are replaced at a reducing rate as we age. At age 25, about 1% of cells are replaced every year. Replacement slows gradually to about 0.5% at age 70.