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List of 34 causes of Mucus buildup. This section shows a full list of all the diseases and conditions listed as a possible cause of Mucus buildup in our database from various sources. 1  Adenovirus. 2  Allergic rhinitis. 3  Allergies. 4  Antrochoanal polyp. 5  Asthma. 6  Atrophic rhinitis. 7  Bronchitis.
When the body starts to produce too much mucus, it accumulates in the lungs among other areas, and the problems begin. Coughing, breathing trouble, chest pain, discomfort in the chest area, and fatigue are some of the symptoms that characterise the build-up of mucus in the lungs.