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To best minimize your risk, consume less than 100 milligrams of caffeine per day, or no more than 1 to 2 cups of coffee. Caffeine may also have adverse impacts in children, such as disturbing their sleep, and intake should be limited to 2.5 milligrams of caffeine per kilogram of their body weight per day.
The researchers found that younger men who passed the 28-cup weekly threshold â which works out to about four cups per day â had a 56 percent increased risk of death from all causes. Younger women who were heavy coffee drinkers had a greater than two-fold increased mortality risk.