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List of 34 causes of Mucus buildup. This section shows a full list of all the diseases and conditions listed as a possible cause of Mucus buildup in our database from various sources. 1  Adenovirus. 2  Allergic rhinitis. 3  Allergies. 4  Antrochoanal polyp. 5  Asthma. 6  Atrophic rhinitis. 7  Bronchitis.
GERD Leads to Mucous Production in the Throat. Stomach contents are acidic in nature. Our esophagus is not prepared to handle it and gets corroded. The acid irritates the throat. In response, the mucosal lining of the throat produces thick, sticky mucous. The patient feels as if something is constantly sticking in the throat. This phlegm may cause chronic cough in a long run. You may visit a doctor and get evaluated.