Peripheral neuropathy affects the nerves in your toes, feet, legs, hands, and arms. Peripheral neuropathy may also cause muscle weakness and loss of reflexes, especially at the ankle, leading to changes in the way a person walks. Foot deformities, such as hammertoes and the collapse of the midfoot, may occur.
The vascular system, also called the circulatory system, is made up of the vessels that carry blood and lymph through the body. The arteries and veins carry blood throughout the body, delivering oxygen and nutrients to the body tissues and taking away tissue waste matter.
NOTE The function of veins is to return blood to the heart. Veins have thinner walls and have one way valves in them. 1  those that take blood from the heart to the lungs to be re-oxygenated; known as the pulmonary arteries. 2  These are the only arteries that transport de-oxygenated blood.