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Glucosamine and Chondroitin Sulfate Side Effects. In general, glucosamine and chondroitin sulfate nutritional supplements appear to be quite safe. The most common side effects occur that have been reported are gastrointestinal in nature, such as upset stomach, nausea, heartburn, and diarrhea.ombined with other osteoarthritis treatments (as deemed appropriate by a physician), taking glucosamine and chondroitin sulfate dietary supplements may help some patients attain optimal levels of relief from osteoarthritis-related joint pain.
no because chondroitin are commonly used to cure arthritis that are not cause by gout while glucosamine commonly fluids produced by our bodies and commonly found in our kidneys!!! some arthritis are cause by gout, but if have this you must seek a cure for your gout not for your arthritis.