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Neomycin is an aminoglycoside antibiotic found in many topical medications such as creams, ointments, and eyedrops. The discovery of neomycin dates back to 1949.It was discovered in the lab of Selman Waksman, who was later awarded the Nobel Prize in Physiology or Medicine in 1951. Neomycin belongs to aminoglycoside class of antibiotics that contain two or more aminosugars connected by glycosidic bonds.minoglycosides such as neomycin are known for their ability to bind to duplex RNA with high affinity. The association constant for neomycin with A-site RNA has been found to be in the 10 9 M â1 range. However, more than 50 years after its discovery, its DNA-binding properties were still unknown.
Drug Name: NEOMYCIN/COLIST/HC/THONZ-OTIC. Other Brand Names: Cortisporin-TC. Uses: This ear drop is used to treat outer ear infections caused by bacteria (also known as swimmer's ear). This product contains neomycin and colistin, which are antibiotics that work by stopping the growth of bacteria.t also contains hydrocortisone, which is an anti-inflammatory corticosteroid that works by reducing ear swelling and discomfort, and thonzonium, which helps this medication pass through dead cells and pus inside the ear. This medication treats only bacterial ear infections.