The rate for the last 1/3 of the taper should be reduced to  of that for the first 2/3. Clonazepam is one of the nitro-benzodiazepines series, i.e. nitrazepam, flunitrazepam, clonazepam, and nimetazepam. It has a half-life of 20-50 hours and accumulates from 1.5 to 3 times the daily dose level.
Noun. 1. myeloma-a tumor of the bone marrow (usually malignant) composed of cells normally found in bone marrow. malignant neoplasm, malignant tumor, metastatic tumor-a tumor that is malignant and tends to spread to other parts of the body.
Definition of Multiple Myeloma. Multiple myeloma is form of blood cancer that develops in the bone marrow. In multiple myeloma, normal plasma cells transform into malignant myeloma cells and produce large quantities of an abnormal immunoglobulin called monoclonal protein or M protein.