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Certain neurons can repair themselves while others can't. Neurons that can repair themselves are refreed to as white matter. The reason white matter can repair itself is because the axons of white matter are myelinated.
Mindset, behavior, and chronic stress are never fixed. The power of neuroplasticity makes it possible to change brain structure and function throughout your lifespan. You can consciously make daily choices of mindset and behavior that will improve the structure and connectivity of your brain. In 2012, Alex Schlegel from Dartmouth College published a study showing that the adult brain can change for the better.