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Toxic doses, over 10 grams per day for an adult, are much higher than typical doses of under 500 milligrams per day. A cup of coffee contains 80â175 mg of caffeine, depending on what bean (seed) is used and how it is prepared (e.g. drip, percolation, or espresso). Thus it requires roughly 50â100 ordinary cups of coffee to reach a lethal dose.
In general, 200 milligrams of caffeine is equal to one 12-ounce cup of coffee, but coffee drinkers should be aware that there can be tremendous discrepancies in different brews. For example, a grande 16-ounce Starbucks brewed coffee has 320 milligrams of caffeine.