The following are additional Purdue OWL resources to help you write your cover letter: 1  Cover Letter Workshop- Formatting and Organization. 2  Example Employment Documents. 3  Cover Letters 1: Quick Tips. 4  Cover Letters 2: Preparing to Write a Cover Letter. 5  Cover Letter Presentation. 6  Job Search Documents for Working Class Positions.
1 IgG deficiency with hyper-IgM is a disease that results when the B-cell fails to switch from making IgM to IgG. 2  This produces an increase in the amount of IgM antibodies present and a decrease in the amount of IgG antibodies. 3  This disease is the result of a genetic mutation.
IgG Subclass Deficiency. The main immunoglobulin (Ig) in human blood is IgG. This is the second most abundant circulating protein and contains long-term protective antibodies against many infectious agents. IgG is a combination of four slightly different types of IgG called IgG subclasses: IgG1, IgG2, IgG3 and IgG4.he IgG class of antibodies is composed of four different subtypes of IgG molecules called the IgG subclasses. These are designated IgG1, IgG2, IgG3 and IgG4. Patients with persistently low levels of one or two IgG subclasses and a normal total IgG level have a selective IgG subclass deficiency.