Why We Donât Know The Size Of The Transgender Population. In 2001, Kerith Conron was working on LGBT issues in Bostonâs health department. She discovered that homeless transgender people were sleeping on benches because the shelters, which were segregated by gender, didnât know what to do with them.
Chromosome abnormalities usually occur when there is an error in cell division. There are two kinds of cell division, mitosis and meiosis. Mitosis results in two cells that are duplicates of the original cell. One cell with 46 chromosomes divides and becomes two cells with 46 chromosomes each.
The chromosomal defect in the Philadelphia chromosome is a translocation, in which parts of two chromosomes, 9 and 22, swap places. The result is that a fusion gene is created by juxtaposing the ABL1 gene on chromosome 9 (region q34) to a part of the BCR (breakpoint cluster region) gene on chromosome 22 (region q11).