Peripheral neuropathy affects the nerves in your toes, feet, legs, hands, and arms. Peripheral neuropathy may also cause muscle weakness and loss of reflexes, especially at the ankle, leading to changes in the way a person walks. Foot deformities, such as hammertoes and the collapse of the midfoot, may occur.
Your blood is pumped around by the heart which is the main function in your circulatory system. The heart sends blood through your blood vessels. The circulatory system consists of the heart, blood vessels, lymph, blood, and the lymphatic vessels and glands.
The circulatory system comprises of the heart, the lungs and the  blood vessels. The main objective of the circulatory system is  transporting oxygenated (rich saturation of oxygen) blood around  the body. The de-oxygenated blood enters through the vena cava and  into the right atrium of the heart.he circulatory system includes: the pulmonary circulation, a loop through the lungs where blood is oxygenated; and the systemic circulation, a loop through the rest of the body to provide oxygenated blood.