1 Dagobert II, 679; he was one of the last kings of the Merovingian line, murdered by persons unknown in the Ardennes Forest on December 23.  Giovanni Borgia, 2nd Duke of Gandia, 1497; his body was recovered in the Tiber with his throat slit and about nine stab wounds on his torso.
Bottlenecks and Founder Effects. Genetic drift can cause big losses of genetic variation for small populations. Population bottlenecks occur when a populations size is reduced for at least one generation.ottlenecks and Founder Effects. Genetic drift can cause big losses of genetic variation for small populations. Population bottlenecks occur when a populations size is reduced for at least one generation.
This article is a good article explaining how the founder effects affect genetic drift. An example of a bottleneck effect: Northern elephant seals have reduced genetic variation most likely due to being hunted. Hunting reduced their population size to as few as 20 individuals at the end if the 19th century.