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Noun. 1. cytotoxic T cell-T cell with CD8 receptor that recognizes antigens on the surface of a virus-infected cell and binds to the infected cell and kill it. CD8 cell, CD8 T cell, killer cell, killer T cell. T cell, T lymphocyte-a small lymphocyte developed in the thymus; it orchestrates the immune system's response to infected or malignant cells.
cytotoxic T cell. A CD8+ T lymphocyte that can destroy microorganisms directly through the release of perforin and proteolytic enzymes. These cells are particularly important in the defense against viruses, rejection of allografts, and, possibly, new malignant cells. Synonym: CD8 cell; cytotoxic cel; killer T cell.