Several mechanisms of action have been proposed to explain the neuroprotective effects of MgSO4 (Figure 2). Magnesium is a calcium antagonist that acts both intracellularly and extracellularly,68 and may act directly on cerebral endothelial cells.
The claim that Hassan Rouhani, the new president of Iran, is a âmoderate,â with whom Western leaders can do business on the basis of mutual self-interest, brings to mind an earlier fantasy common among elites in the West after the death of the Soviet dictator, Leonid Brezhnev, in 1982: that his successor as General Secretary, Yuri Andropov, was a closet liberal eager to reduce the tensions of the Cold War, then nearly four decades old, and thereby make nuclear war less likely.
When the deal was finally reached in July 2015, he lost no time in appearing on television to remind people he had fulfilled his election pledge. In the ongoing internal power struggle between Iran's hardliners and moderates, the agreement shored up Mr Rouhani's position.