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Connatal Pelizaeus-Merzbacher disease is the more severe of the two types. Symptoms can begin in infancy and include problems feeding, a whistling sound when breathing, progressive spasticity leading to joint deformities (contractures) that restrict movement, speech difficulties (dysarthria), ataxia, and seizures.
PMS mood swings are called labile mood, a fluctuation of mood, by doctors, and is one of the most common and troublesome PMS symptoms. You may notice alternating depression and anger, or feeling suddenly unable to control your tension and anxiety, or even feeling sad and tearful for no apparent reason.he bottom line is that for days or weeks before your period, you may feel that your moods and behavior are out of your own control. These premenstrual mood swings usually happen against a background of an overall depressed, anxious, or tense mood.