A population PK analysis in patients with major depressive disorder showed no substantial change in plasma concentrations of fluoxetine (20 or 40 mg/day), paroxetine CR (37.5 or 50 mg/day), or sertraline (100 or 150 mg/day) dosed to steady-state.
The definition of advise is to offer a suggestion about what should be done in a situation. A mother warning her child to bring rain boots and an umbrella to an outdoor activity on a day that rain is expected is an example of advise. -Â·visedâ², -Â·visâ²ing. 1  to give advice or an opinion to; counsel. 2  to offer as advice; recommend.  to notify; inform: he was advised of the facts.
1. 'advice'. Advice. is a noun. If you give someone advice, you tell them what you think they should do. Take my advice  stay away from him! She promised to follow his advice. Advice is an uncountable noun. Don't talk about ' advices ' or ' an advice '. However, you can talk about a piece of advice.