The following are additional Purdue OWL resources to help you write your cover letter: 1  Cover Letter Workshop- Formatting and Organization. 2  Example Employment Documents. 3  Cover Letters 1: Quick Tips. 4  Cover Letters 2: Preparing to Write a Cover Letter. 5  Cover Letter Presentation. 6  Job Search Documents for Working Class Positions.
1 IgG deficiency with hyper-IgM is a disease that results when the B-cell fails to switch from making IgM to IgG. 2  This produces an increase in the amount of IgM antibodies present and a decrease in the amount of IgG antibodies. 3  This disease is the result of a genetic mutation.
If IgG or IgA concentrations are decreased, or a deficiency in one of their subclasses is suspected, then subclass testing may be performed to detect and further define the deficiency. Subclass deficiencies can be present even when an immunoglobulin class concentration, such as IgG, is normal.