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Generally, laboratory mice become sexually mature between fi ve and eight weeks of age. Males of most. strains usually mature sexually by six weeks of age. DBA/2J (000671) and C3H/HeJ (000659) mice are precocious: females can. conceive when they are as young as 23 days old.
If you have decided to breed your rats, you must also consider their age. The best time to breed a female for the first time is at 4-5 months of age. It can be dangerous to breed a female older than 6-8 months of age for the first time, since her pelvic canal will be fused in a narrow position.ats can reach sexual maturity at 5 weeks of age, so the sexes should be separated prior to this age. Rats do not recognize incest, so brothers and sisters and even mothers and sons must be separated. Rats do not have a breeding season, although very hot or cold temperatures will reduce breeding.