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Homocysteine is an amino acid. Amino acids are the building blocks of proteins. When proteins break down, elevated levels of amino acids like homocysteine may be found in the bloodstream. Having elevated levels of homocysteine in the blood (hyperhomocysteinemia) is associated with atherosclerosis and blood clots. It is not possible to get homocysteine from the diet. It must be made from methionine, another amino acid that is found in meat, fish, and dairy products.
Folic acid works to convert the amino acid homocysteine into methionine. Folic acid deficiency allows homocysteine levels to accumulate in the body. High levels of homocysteine are associated with heart disease and stroke.epression. Low levels of folic acid in the body have been linked to depression. A study published in the January 2005 issue of the Journal of Psychopharmacology found that people in certain cultures, with diets rich in folic acid, were less at risk for depression.