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Individuals most impacted by the rising cost of insulin are the uninsured and the under-insured. These patients are forced to pay the ever-increasing retail sale price (which is increasing due to a variety of factors, including increased wholesale price) or a percentage of this price when buying insulin.
Then in turn the blood sugar will drop or crash after such an insulin spike. Now the adrenals have to respond to bring the blood sugar back up. Do this again and again, day in and day out like most Americans do and you are killing your adrenal function. Low blood sugar, or hypoglycemia leads to insulin resistance.