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1. of or relating to an interstice or interstices. 2. (Chemistry) physics forming or occurring in an interstice: an interstitial atom. 3. (Chemistry) chem containing interstitial atoms or ions: an interstitial compound. 4. (Biology) anatomy zoology occurring in the spaces between organs, tissues, etc: interstitial cells.
It is here where molecules are exchanged between the blood and the interstitial fluid. The interstitial fluid is the liquid that has been forced by pressure from the capillaries, has gathered in the tissue spaces, and surrounds the cells of the tissues of the body.