Symptoms of Hashimoto's Thyroiditis: Introduction. The types and severity of symptoms of Hashimoto's disease vary between individuals. Many people have no symptoms at all. If Hasimoto's disease leads to hypothyroidism, symptoms of an underactive thyroid may develop. At the onset of hypothyroidism, symptoms can be vague and develop slowly. They may not include weakness, weight gain, cold sensitivity, cold hands and feet, fatigue, dry skin, brittle nails, and thinning, brittle hair.
Ligand Binding Assays (LBA) is an assay, or an analytic procedure, whose procedure or method relies on the binding of ligand molecules to receptors, antibodies or other macromolecules.on specific binding refers to the binding of a ligand to something other than its designated receptor such as various other receptors, or different types of transporters in the cell membrane. For example, various antagonists can bind to multiple types receptors.
Receptor Biology: Steven M. Sine. Ligand Binding. Binding of the transmitter substance is the initial step in the function of synaptic receptors. In this binding process, a precise molecular match is made between the nerve-released transmitter and the receptor binding pocket.