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List of 34 causes of Mucus buildup. This section shows a full list of all the diseases and conditions listed as a possible cause of Mucus buildup in our database from various sources. 1  Adenovirus. 2  Allergic rhinitis. 3  Allergies. 4  Antrochoanal polyp. 5  Asthma. 6  Atrophic rhinitis. 7  Bronchitis.
As you know, nasal mucus is normally clear and thin. During times of infection, it can change color to yellow or green either as a result of trapped bacteria or due to your body's reaction to viral infection. Mucus build-up is also caused by cystic fibrosis with extremely thick production of mucus that is difficult to expel. However, sometimes the problem is not that you are producing too much mucus, but that it's not being cleared away effectively.