Peripheral neuropathy affects the nerves in your toes, feet, legs, hands, and arms. Peripheral neuropathy may also cause muscle weakness and loss of reflexes, especially at the ankle, leading to changes in the way a person walks. Foot deformities, such as hammertoes and the collapse of the midfoot, may occur.
The vascular system, also called the circulatory system, is made up of the vessels that carry blood and lymph through the body. The arteries and veins carry blood throughout the body, delivering oxygen and nutrients to the body tissues and taking away tissue waste matter.
One primary function of the circulatory system is the transport of oxygen from the lungs to the cells. This is why the system has two basic parts: the pulmonary circulation, which takes blood to the lungs to pick up oxygen, and systemic circulation, which takes the oxygenated blood throughout the body.