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Individuals most impacted by the rising cost of insulin are the uninsured and the under-insured. These patients are forced to pay the ever-increasing retail sale price (which is increasing due to a variety of factors, including increased wholesale price) or a percentage of this price when buying insulin.
Fat around the middle is worse than fat anywhere else, itâs where the damage starts in terms of insulin resistance and inflammatory proteins. Van Cauter: Obesity is the major cause of insulin resistance, insulin resistance could also result from an activation of stress-responsive pathways which tend to antagonize the action of insulin. De Felice: