Both tramadol and hydrocodone attach to receptors in your brain to change your perception of pain. However, tramadol also allows the chemical messengers norepinephrine and serotonin to remain available to your brain for a longer period. It is believed that this helps block pain signals in your spinal cord.
In cinematography, the Dutch angle is one of many cinematic techniques often used to portray psychological uneasiness or tension in the subject being filmed.
Huisgenoot (Afrikaans for House Companion) is a weekly Afrikaans-language general interest family magazine. It has the highest circulation figures of any South African magazine and is followed by sister magazine YOU, its English-language version. A third magazine, Drum, is directed at the black market. yearly Skouspel concert is also held in Cape Town. Huisgenoot launched a few successful line extensions in 2010, including recipe and blockbuster titles. In July 2012, the magazine also launched its first reality television show, in conjunction with the Afrikaans television channel kykNET.