The use of Ribavirin to treat chronic hepatitis C in patients receiving azathioprine has been reported to induce severe pancytopenia and may increase the risk of azathioprine-related myelotoxicity. Inosine monophosphate dehydrogenase (IMDH) is required for one of the metabolic pathways of azathioprine.
There are several common underlying causes of kidney disease. 1  In older cats Interstitial Nephritis is most frequently seen. 2  Polycystic Kidney Disease (PKD) is a very common problem in Persian cats - 20-30% of them can be affected. 3  Tumours are occasionally seen in middle-aged and older cats.
Roundworms are most commonly passed from adult mother cats to their kittens through the mammary glands. Kittens are at highest risk for health concerns related to roundworm infection, but adult cats can be infected by ingesting eggs from infected feces or intermediate hosts such as earthworms or rodents. Roundworm infection is called 'ascariasis' and generally does not produce symptoms in adult cats.