The use of Ribavirin to treat chronic hepatitis C in patients receiving azathioprine has been reported to induce severe pancytopenia and may increase the risk of azathioprine-related myelotoxicity. Inosine monophosphate dehydrogenase (IMDH) is required for one of the metabolic pathways of azathioprine.
There are several common underlying causes of kidney disease. 1  In older cats Interstitial Nephritis is most frequently seen. 2  Polycystic Kidney Disease (PKD) is a very common problem in Persian cats - 20-30% of them can be affected. 3  Tumours are occasionally seen in middle-aged and older cats.
Feline infectious peritonitis. FIP-infected kidney showing inflammatory response. Feline infectious peritonitis (FIP) is a fatal, incurable disease that affects cats. It is caused by Feline Infectious Peritonitis Virus (FIPV), which is a mutation of Feline Enteric Coronavirus (FECV) â (Feline coronavirus FCoV). Experts do not agree on the specifics of genetic changes that produce the FIPV.