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Weight loss happens fast after gastric sleeve surgery: 1  Month 3: About 1/3 of excess weight is gone. 2  Month 6: About half of excess weight is gone.  Month 12: Up to 70% of excess weight is gone.
The anti-diabetes effect of sleeve gastrectomy is seen even before losing weight. There is evidence that Ghrelin promotes insulin resistance and block insulin release by the pancreas. The reduced Ghrelin levels after sleeve gastrectomy increase the capacity for insulin release in response to a meal.