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Individuals most impacted by the rising cost of insulin are the uninsured and the under-insured. These patients are forced to pay the ever-increasing retail sale price (which is increasing due to a variety of factors, including increased wholesale price) or a percentage of this price when buying insulin.
Unfortunately for Medicare, the annual wholesale costs of Praluent and Repatha are $14,600 and $14,100, respectively. This is a chronic condition, so these medications would be used throughout a person's lifetime -- meaning PCSK9 inhibitors could be ground zero for the undoing of Medicare.