A population PK analysis in patients with major depressive disorder showed no substantial change in plasma concentrations of fluoxetine (20 or 40 mg/day), paroxetine CR (37.5 or 50 mg/day), or sertraline (100 or 150 mg/day) dosed to steady-state.
The definition of advise is to offer a suggestion about what should be done in a situation. A mother warning her child to bring rain boots and an umbrella to an outdoor activity on a day that rain is expected is an example of advise. -Â·visedâ², -Â·visâ²ing. 1  to give advice or an opinion to; counsel. 2  to offer as advice; recommend.  to notify; inform: he was advised of the facts.
To advise someone is to give them advice, or counsel. If you live in Iceland and a friend visiting you from Hawaii asks what he should pack, advise him to bring warm clothes and snow boots. Advise comes from a Latin word for vision. We want people to advise us if we think they can see the whole picture better than we can. For this reason, we often seek the advice of trained people. Financial advisors advise their clients on which funds to invest in. Legal advisors advise their clients on the law.