The use of Ribavirin to treat chronic hepatitis C in patients receiving azathioprine has been reported to induce severe pancytopenia and may increase the risk of azathioprine-related myelotoxicity. Inosine monophosphate dehydrogenase (IMDH) is required for one of the metabolic pathways of azathioprine.
There are several common underlying causes of kidney disease. 1  In older cats Interstitial Nephritis is most frequently seen. 2  Polycystic Kidney Disease (PKD) is a very common problem in Persian cats - 20-30% of them can be affected. 3  Tumours are occasionally seen in middle-aged and older cats.
Types of Kidney Disease. There are two types of kidney failure in cats. Each has different causes, treatments, and outlooks. Acute renal failure develops suddenly, over a matter of days or weeks. It happens in cats of all ages and is usually the result of: 1  Poisons, which are the most common cause of acute renal failure.