The use of Ribavirin to treat chronic hepatitis C in patients receiving azathioprine has been reported to induce severe pancytopenia and may increase the risk of azathioprine-related myelotoxicity. Inosine monophosphate dehydrogenase (IMDH) is required for one of the metabolic pathways of azathioprine.
There are several common underlying causes of kidney disease. 1  In older cats Interstitial Nephritis is most frequently seen. 2  Polycystic Kidney Disease (PKD) is a very common problem in Persian cats - 20-30% of them can be affected. 3  Tumours are occasionally seen in middle-aged and older cats.
Causes of Urinary Tract Infections. Urinary tract infections (UTIs) in cats are caused by microorganisms that enter the urinary tract, travel through the urethra and typically settle in the bladder. The urethra is the tube that connects the urinary bladder to the outside world. Infection of the bladder caused by bacteria is called âbacterial cystitis.â Occasionally, other organisms are the culprit, including mycoplasma, viruses, algae and fungi. Sometimes, the infective organisms migrate from the bladder through the ureters, lodging in the kidneys.