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Two to three days after getting a tuberculin skin test, the size of any bump at the site is measured. 1  Positive, meaning you have been infected with TB bacteria.  Negative, meaning you have not been infected with TB bacteria or your body cannot respond to the protein injected because of a weakened immune system.
There are two tests that can be used to help detect TB infection. The Mantoux TB skin test is performed by injecting a small amount of fluid (called PPD tuberculin) into the skin in the lower part of the arm. If you get the TB skin test, you have to return within 48 to 72 hours to have a trained health care worker look for a reaction (bump) on your arm.