Definition of solubility. 1) The amount of a solute that will dissolve in a specific solvent under given conditions.
The small intestine is where most chemical digestion takes place. Most of the digestive enzymes in the small intestine are secreted by the pancreas and enter the small intestine via the pancreatic duct. These enzymes enter the small intestine in response to the hormone cholecystokinin, which is produced in response to the presence of nutrients.
It originates in the pancreas but works in the small intestine. lipase is produced in the pancreas and is secreted by the small intestine. In the Small Intestine, Carbohydrase, Protease and Lipase is found, but Lipid is formed into fatty acids and glycerol by the way. So main answer from me: Small Intestine.