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Noun. 1. cytotoxic T cell-T cell with CD8 receptor that recognizes antigens on the surface of a virus-infected cell and binds to the infected cell and kill it. CD8 cell, CD8 T cell, killer cell, killer T cell. T cell, T lymphocyte-a small lymphocyte developed in the thymus; it orchestrates the immune system's response to infected or malignant cells.
There are four types of T cells, each with a special purpose. 1  Helper T cells detect infection and get the other cells of the immune system ready for battle. 2  Cytotoxic, or killer, T cells destroy infected cells. 3  Regulatory T cells tell the immune system when the battle with the pathogens is over and to stop fighting.