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Researchers say consumption of artificial sweeteners such as saccharin, sucralose and aspartame led to increased risk of glucose intolerance, a condition linked to diabetes. Sweet âN Low contains saccharin. Equal original contains aspartame. Splenda contains sucralose.
Explore: Understanding Carbohydrates. 1  Glycemic Index and Diabetes Learn about the glycemic index and if it can help you manage diabetes. 2  Low-Calorie Sweeteners Low-calorie sweeteners are also called artificial sweeteners, sugar substitutes or non-nutritive sweeteners.