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The exact cause of atopic dermatitis (eczema) is unknown. Healthy skin helps retain moisture and protects you from bacteria, irritants and allergens. Eczema is likely related to a mix of factors:1  Dry, irritable skin, which reduces the skin's ability to be an effective barrier.2  A gene variation that affects the skin's barrier function.ealthy skin helps retain moisture and protects you from bacteria, irritants and allergens. Eczema is likely related to a mix of factors: 1  Dry, irritable skin, which reduces the skin's ability to be an effective barrier. 2  A gene variation that affects the skin's barrier function.
The exact causes of eczema are unknown. You might have inherited a tendency for eczema. You may have a family member who has eczema or who has hay fever (allergic rhinitis) or asthma. Many doctors think eczema causes are linked to allergic disease, such as hay fever or asthma.Doctors call this the atopic triad. Many children with eczema (up to 80%) will develop hay fever and/or asthma.he exact causes of eczema are unknown. You might have inherited a tendency for eczema. You may have a family member who has eczema or who has hay fever (allergic rhinitis) or asthma. Many doctors think eczema causes are linked to allergic disease, such as hay fever or asthma. Doctors call this the atopic triad.