The use of Ribavirin to treat chronic hepatitis C in patients receiving azathioprine has been reported to induce severe pancytopenia and may increase the risk of azathioprine-related myelotoxicity. Inosine monophosphate dehydrogenase (IMDH) is required for one of the metabolic pathways of azathioprine.
There are several common underlying causes of kidney disease. 1  In older cats Interstitial Nephritis is most frequently seen. 2  Polycystic Kidney Disease (PKD) is a very common problem in Persian cats - 20-30% of them can be affected. 3  Tumours are occasionally seen in middle-aged and older cats.
It is important to understand and recognize kidney infection symptoms in your cat because early diagnosis and proper treatment can prevent complications. The majority of urinary tract infections are caused by bacteria that can enter the cat's body through the urethra. Bacteria can cause a bladder infection (bacterial cystitis), however bacteria may ascend up towards the kidney and renal pelvis and cause a kidney infection (pyelonephritis).