The use of Ribavirin to treat chronic hepatitis C in patients receiving azathioprine has been reported to induce severe pancytopenia and may increase the risk of azathioprine-related myelotoxicity. Inosine monophosphate dehydrogenase (IMDH) is required for one of the metabolic pathways of azathioprine.
There are several common underlying causes of kidney disease. 1  In older cats Interstitial Nephritis is most frequently seen. 2  Polycystic Kidney Disease (PKD) is a very common problem in Persian cats - 20-30% of them can be affected. 3  Tumours are occasionally seen in middle-aged and older cats.
Healthy Kidneys. Your cat's kidneys keep him healthy by flushing toxins out through his urine. Every drop of blood in your cat's body is pumped through the kidneys for filtering to prevent the buildup of toxic substances that result from the normal metabolite process.rine that's brown or red contains blood and could point to a problem with his kidneys. He could have kidney stones or an infection, or he could suffer from kidney disease. In you notice any change in your cat's urine or litter box usage, call your vet.