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Two to three days after getting a tuberculin skin test, the size of any bump at the site is measured. 1  Positive, meaning you have been infected with TB bacteria.  Negative, meaning you have not been infected with TB bacteria or your body cannot respond to the protein injected because of a weakened immune system.
From infection to development of a positive TB skin test reaction (the incubation period) is approximately 2 to 12 weeks.The risk for developing active disease is the highest in the first two years after infection and development of a positive TB skin test reaction.fter an exposure to infectious tuberculosis, a TB skin test reaction of 5 mm induration or greater is considered positive. You will then be evaluated for signs and symptoms of active tuberculosis (cough lasting for more than three weeks, bloody sputum, fever, night sweats, weight loss, loss of appetite, fatigue).