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List of 34 causes of Mucus buildup. This section shows a full list of all the diseases and conditions listed as a possible cause of Mucus buildup in our database from various sources. 1  Adenovirus. 2  Allergic rhinitis. 3  Allergies. 4  Antrochoanal polyp. 5  Asthma. 6  Atrophic rhinitis. 7  Bronchitis.
Food Allergies or Sensitivities. Rarely, food allergies/sensitivities can cause throat mucosa irritation and/or excessive throat mucus to develop triggering throat-clearing. The most common culprit is dairy products though reactions to egg, wheat, rice, soy, etc are also possible. Treatment for this problem is mainly avoidance.