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Common causes of abnormal heart rhythms (arrhythmias) or conditions that can lead to arrhythmias include: 1  Heart defects you're born with (congenital heart defects). 2  Coronary artery disease. 3  High blood pressure. 4  Diabetes.
Along with being overweight or obese, the following conditions will put you at greater risk for heart disease and other conditions: Risk Factors. 1  High blood pressure (hypertension). 2  High LDL cholesterol (bad cholesterol). 3  Low HDL cholesterol (good cholesterol). 4  High triglycerides. 5  High blood glucose (sugar).