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To best minimize your risk, consume less than 100 milligrams of caffeine per day, or no more than 1 to 2 cups of coffee. Caffeine may also have adverse impacts in children, such as disturbing their sleep, and intake should be limited to 2.5 milligrams of caffeine per kilogram of their body weight per day.
Over 2.25 billion cups of coffee are consumed in the world every day. Over 90% of coffee production takes place in developing countries - mostly South America, while consumption happens mainly in the industrialized economies.