Local Weather; Holiday Weather; Marine Weather; Hill & Mountain Weather; Where's Good Weather
Connatal Pelizaeus-Merzbacher disease is the more severe of the two types. Symptoms can begin in infancy and include problems feeding, a whistling sound when breathing, progressive spasticity leading to joint deformities (contractures) that restrict movement, speech difficulties (dysarthria), ataxia, and seizures.
Symptoms. The most common symptom of polymyalgia rheumatica (PMR) is pain and stiffness in the shoulder muscles, which develops quickly over a few days or weeks. You may also have pain in your neck and hips. Both sides of the body are usually affected.