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Common causes of abnormal heart rhythms (arrhythmias) or conditions that can lead to arrhythmias include: 1  Heart defects you're born with (congenital heart defects). 2  Coronary artery disease. 3  High blood pressure. 4  Diabetes.
Key Facts. Many risks for heart disease and strokeâincluding high blood pressure and high cholesterolâmay not have any symptoms. Many of these risksâspecifically high blood pressure, high cholesterol, smoking, and obesityâare preventable and controllable. Controlling these risks could reduce your risk for heart attack or stroke by more than 80%. About 160,000 people who died from cardiovascular disease in 2014 were younger than age 65.