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Antipsychotics. Antipsychotic medicines, also known as neuroleptics, are usually recommended as the first treatment for psychosis. They work by blocking the effect of dopamine (a chemical that transmits messages in the brain). However, they're not suitable or effective for everyone, as side effects can affect people differently.
1 You can experience psychosis for a wide variety of reasons. 2  For example it can be due to having a mental illness such as schizophrenia or bipolar disorder. 3  It can also be caused by drug use, brain injury or extreme stress.