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Glucosamine and Chondroitin Sulfate Side Effects. In general, glucosamine and chondroitin sulfate nutritional supplements appear to be quite safe. The most common side effects occur that have been reported are gastrointestinal in nature, such as upset stomach, nausea, heartburn, and diarrhea.ombined with other osteoarthritis treatments (as deemed appropriate by a physician), taking glucosamine and chondroitin sulfate dietary supplements may help some patients attain optimal levels of relief from osteoarthritis-related joint pain.
It is not known whether chondroitin and glucosamine will harm an unborn baby. Do not use this product without medical advice if you are pregnant. Chondroitin and glucosamine may pass into breast milk and may harm a nursing baby. Do not use this product without medical advice if you are breast-feeding a baby. Do not give any herbal/health supplement to a child without medical advice.