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Generally, laboratory mice become sexually mature between fi ve and eight weeks of age. Males of most. strains usually mature sexually by six weeks of age. DBA/2J (000671) and C3H/HeJ (000659) mice are precocious: females can. conceive when they are as young as 23 days old.
How old should mice be when I get them? Baby mice are fully weaned from their mother at about four weeks old, but they benefit a lot from staying with their litter mates for another week-the disruption of leaving both mother, sibilings and home in one day is a lot to cope with.Ideally they should not leave the litter before 5 weeks of age.aby mice are fully weaned from their mother at about four weeks old, but they benefit a lot from staying with their litter mates for another week-the disruption of leaving both mother, sibilings and home in one day is a lot to cope with. Ideally they should not leave the litter before 5 weeks of age.