The use of Ribavirin to treat chronic hepatitis C in patients receiving azathioprine has been reported to induce severe pancytopenia and may increase the risk of azathioprine-related myelotoxicity. Inosine monophosphate dehydrogenase (IMDH) is required for one of the metabolic pathways of azathioprine.
There are several common underlying causes of kidney disease. 1  In older cats Interstitial Nephritis is most frequently seen. 2  Polycystic Kidney Disease (PKD) is a very common problem in Persian cats - 20-30% of them can be affected. 3  Tumours are occasionally seen in middle-aged and older cats.
The main causes of blood loss in cats include: 1  Trauma or injury to blood vessels or internal organs resulting in bleeding. 2  Severe parasitic infestations with fleas, ticks, and hookworms. 3  Tumors of the intestinal tract, kidneys, and urinary bladder.  Diseases that prevent proper clotting of blood.