The use of Ribavirin to treat chronic hepatitis C in patients receiving azathioprine has been reported to induce severe pancytopenia and may increase the risk of azathioprine-related myelotoxicity. Inosine monophosphate dehydrogenase (IMDH) is required for one of the metabolic pathways of azathioprine.
There are several common underlying causes of kidney disease. 1  In older cats Interstitial Nephritis is most frequently seen. 2  Polycystic Kidney Disease (PKD) is a very common problem in Persian cats - 20-30% of them can be affected. 3  Tumours are occasionally seen in middle-aged and older cats.
Kidney Failure - Acute in Cats. What is acute renal failure? Acute renal failure (ARF) or acute kidney failure refers to the sudden failure of the kidneys to perform normal filtration duties. This is not the same as the much more common form of kidney failure, chronic renal failure (CRF). ARF leads to accumulation of toxins and other metabolic wastes in the bloodstream, dehydration, electrolyte imbalances and disturbances in the acid-base balance of the blood.