A. PTE name B. PTE FEIN C. Nonpassive loss D. Section 179 expense E. Nonpassive income 1. (a) (b) (c) 2. (a) (b) (c) 3. (a) (b) (c) 4. (a) (b) (c) 5. (a) (b) (c) 6. Total for each column: (a), (b), and (c) (a) (b) (c) 7. Enter the amount from line 6(c): 7. _____ 8. Add lines 6(a) and 6(b): 8. _____ 9. Line 7 minus line 8: 9.
Mast cells play a key role in the inflammatory process. When activated, a mast cell can either selectively release (piecemeal degranulation) or rapidly release (anaphylactic degranulation) mediators, or compounds that induce inflammation, from storage granules into the local microenvironment.
Notably, mast cell-released heparin generates the inflammatory mediator bradykinin via activation of factor XII (the so-called Hageman Factor) that belongs to the blood coagulation system. The study thus provides an unexpected link between the clotting cascade and mast cell-driven pro-inflammatory reactions.