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1. of or relating to an interstice or interstices. 2. (Chemistry) physics forming or occurring in an interstice: an interstitial atom. 3. (Chemistry) chem containing interstitial atoms or ions: an interstitial compound. 4. (Biology) anatomy zoology occurring in the spaces between organs, tissues, etc: interstitial cells.
Interstitial lung disease, or ILD, is a common term that includes more than 100 chronic lung disorders, which may be: Nonmalignant (noncancerous). Noninfectious. Interstitial lung diseases are named after the tissue between the air sacs of the lungs called the interstitium--the tissue affected by fibrosis (scarring).