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Polycystic kidney disease symptoms may include: 1  High blood pressure. 2  Back or side pain. 3  Headache. 4  Increase in the size of your abdomen.5  Blood in your urine. 6  Frequent urination. 7  Kidney stones.8  Kidney failure.9  Urinary tract or kidney infections.olycystic kidney disease symptoms may include: 1  High blood pressure. 2  Back or side pain. 3  Headache. 4  Increase in the size of your abdomen. 5  Blood in your urine. 6  Frequent urination. 7  Kidney stones. 8  Kidney failure. 9  Urinary tract or kidney infections.
Polycystic liver disease. 1  Pathophysiology: adult polycystic liver disease is congenital and is usually associated with autosomal dominant polycystic kidney disease with mutations in PRKCSH and SEC63 or PKD1 and PKD2 genes. 2  Presentation: kidney cysts usually occur before liver cysts and chronic kidney disease is common. However, polycystic liver disease rarely leads to hepatic fibrosis and liver failure. Hepatomegaly and abdominal pain may be present.