Damage may be a result of the direct effects of alcohol on the brain or may result indirectly, from a poor general health status or from severe liver disease. For example, thiamine deficiency is a common occurrence in people with alcoholism and results from poor overall nutrition.or example, studies with animals show that high doses of alcohol lead to a disruption in the growth of new brain cells; scientists believe it may be this lack of new growth that results in the longâterm deficits found in key areas of the brain (such as hippocampal structure and function) (31,32).
Full Definition of DOLDRUMS. 1. : a spell of listlessness or despondency. 2. often capitalized: a part of the ocean near the equator abounding in calms, squalls, and light shifting winds.3. : a state or period of inactivity, stagnation, or slump. ADVERTISEMENT.ull Definition of DOLDRUMS. 1. : a spell of listlessness or despondency. 2. often capitalized: a part of the ocean near the equator abounding in calms, squalls, and light shifting winds.
Today the expression carries the contradictory connotations of comfort and discontent, with emphasis on the latter: movement in a fixed course is smooth and easy but deadening. in the doldrums Inactive, stagnant, nonproductive; depressed, in low spirits, in the dumps, in a blue funk. Doldrum derives from dol, an obsolete form of dull, and is itself an obsolete slang term for a dullard. Thus, the doldrums refers to a condition of dullness, low spirits, or depression.