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Generally, laboratory mice become sexually mature between fi ve and eight weeks of age. Males of most. strains usually mature sexually by six weeks of age. DBA/2J (000671) and C3H/HeJ (000659) mice are precocious: females can. conceive when they are as young as 23 days old.
How many litters a year do mice have? Mice normally wait at least two weeks to a month between litters. A mouse can have anywhere from 12 to 24 litters in a single year. With an average of 12 mice per litter, aâ¦ single mouse can give birth to around 144 to 288 babies a year! Lily Garcia.