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In the afatinib group, the most common treatment-related adverse events were diarrhea, rash/acne, and stomatitis; in the chemotherapy group, they were nausea, fatigue, and decreased appetite. Patient-reported outcomes favored afatinib, with better control of cough, dyspnea, and pain, the investigators say.
Keytruda, the immunotherapy drug, was a key part of Jimmy Carterâs cancer treatment. Pembrolizumab was fast-tracked last year after receiving âbreakthrough therapy designationâ from the FDA. The drug was part of Carterâs treatment regimen, which also included targeted radiation to his brain.