Definition of primary and secondary amenorrhea. Amenorrhea is the medical term for the absence of menstrual periods, either on a permanent or temporary basis. Amenorrhea can be classified as primary or secondary.
Most inherited bleeding disorders are the result of abnormal platelet function or a deficiency in one or more of the factors involved in the blood clotting system. The most serious and common inherited coagulation disorders in dogs are hemophilia(deficiency of factor VIII or IX) and von Willebrand's disease (lack of von Willebrand factor). Other coagulation disorders are discussed here.
In the past 30 years, the impact of copper accumulation on hepatic function in dogs has received considerable attention. In some terrier breeds, an inherited metabolic defect compromises copper excretion; in other breeds, primary inflammatory hepatic disease may facilitate copper accumulation because of chronic cholestasis.