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Polycystic kidney disease symptoms may include: 1  High blood pressure. 2  Back or side pain. 3  Headache. 4  Increase in the size of your abdomen.5  Blood in your urine. 6  Frequent urination. 7  Kidney stones.8  Kidney failure.9  Urinary tract or kidney infections.olycystic kidney disease symptoms may include: 1  High blood pressure. 2  Back or side pain. 3  Headache. 4  Increase in the size of your abdomen. 5  Blood in your urine. 6  Frequent urination. 7  Kidney stones. 8  Kidney failure. 9  Urinary tract or kidney infections.
What is polycystic kidney disease? Polycystic kidney disease (also called PKD) causes numerous cysts to grow in the kidneys. These cysts are filled with fluid. If too many cysts grow or if they get too big, the kidneys can become damaged. PKD cysts can slowly replace much of the kidneys, reducing kidney function and leading to kidney failure.