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In the afatinib group, the most common treatment-related adverse events were diarrhea, rash/acne, and stomatitis; in the chemotherapy group, they were nausea, fatigue, and decreased appetite. Patient-reported outcomes favored afatinib, with better control of cough, dyspnea, and pain, the investigators say.
(Also Called 'Remicade for Crohn: Q&A-Medication'). Infliximab, brand name RemicadeÂ®, has been approved by the U.S. Food and Drug Administration for the treatment of Crohn's disease. Infiximab is a biologically engineered antibody that attacks a tumor necrosis factor (TNF) protein that causes intestinal inflammation.ther biologic agents that are now approved for use in Crohnâs disease are: 1  Adalimumab (HumiraÂ®)âa fully human anti-TNF antibody. 2  Certolizumab (CimziaÂ®)âa humanized fragment of an anti-TNF antibody that is pegylated to make it last longer in the body.