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Generally, laboratory mice become sexually mature between fi ve and eight weeks of age. Males of most. strains usually mature sexually by six weeks of age. DBA/2J (000671) and C3H/HeJ (000659) mice are precocious: females can. conceive when they are as young as 23 days old.
Female mice pheromones may excite a male mouse to mate immediately. In addition to producing instinctive behavioral responses, pheromones can also produce changes in an animal's physiology, spurring the onset of puberty or bringing on estrus.