One common cause of SLUDGE is exposure to organophosphorus insecticides (including parathion, malathion, and diazinon) or nerve gas, such as sarin. These agents phosphorylate acetylcholinesterase, thereby irreversibly deactivating acetylcholinesterase and raising acetylcholine levels and causing SLUDGE.
Every stone grants different abilities to its owner. The Infinity Gems (previously known as Soul Gems) are some of the most powerful artifacts in the Universe. Each one allows its owner complete omnipotence over one aspect of the universe: time, space, reality, mind, power, and soul. When all six are directly wielded together, nothing is impossible for their bearer.
The Second Normal Air Gem slot is unlocked at level 26. The Second Normal Fire Gem slot is unlocked at level 30 (Max Level). Normal gems can only be placed in normal gem slots, while empowered slots are reserved for empowered gems. Gems are fragile and may crack when leveling up, so having plenty of boosters can help prevent gems from cracking. If Gems do happen to crack, players can still use the gems but will be unable to be upgraded until players use a Re-Gemerator in order to fix the broken gem (which can be bought from the Store using 500 Cubits).