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The tongue papillae, including the taste buds, can become inflamed. A sore tongue is not always a sign of something more serious. The tongue should be included in good dental health habits. Over time, smoking can make the tongue more sensitive to heat and cold.
1 Enlarged papillae. 2  If one or more of your taste buds becomes inflamed or irritated, it can swell and form a painful bump on your tongue. 3  Certain medical conditions. 4  Medical conditions, including diabetes and anemia, can have a sore tongue as a symptom.