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Though mostly water, the cytosol is full of proteins that control cell metabolism including signal transduction pathways, glycolysis, intracellular receptors, and transcription factors. Cytoplasm is a collective term for the cytosol plus the organelles suspended within the cytosol.
1. Cytosol is the intra-cellular fluid that is present inside the cells. On the other hand, cytoplasm is that part of the cell which is contained within the entire cell membrane. 2. Cytosol comprises of a lot of water, dissolved ions, large water soluble molecules, smaller minute molecules and proteins.