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1 Symptoms and signs of leptospirosis are highly variable and range from no symptoms to nonspecific symptoms including high fever, chills, headache, abdominal symptoms to Weil's disease with organ dysfunction.  Definitive diagnosis is done by isolating the bacteria from the patient; serological tests are also available.
Look for Physical Symptoms. Check your weight. Where are you carrying your body fat and how much is an indicator of leptin resistance. Diabetics and leptin resistant people quickly gain weight in the middle, and have high body fat. Check your sleep. Fatigue and insomnia are symptoms of leptin resistance.