responds to these newer agents. While refractory multiple myeloma is considered to be a disease that does not. respond to a particular therapy, the new definition of relapsed and refractory multiple myeloma includes patients. who show disease progression within 60 days of discontinuing therapy.
In the years since the two atomic bombs were dropped on Japan, a number of historians have suggested that the weapons had a two-pronged objective. First, of course, was to bring the war with Japan to a speedy end and spare American lives.resident Harry S. Truman, warned by some of his advisers that any attempt to invade Japan would result in horrific American casualties, ordered that the new weapon be used to bring the war to a speedy end. On August 6, 1945, the American bomber Enola Gay dropped a five-ton bomb over the Japanese city of Hiroshima.
  The first Atomic Bomb (called little boy) dropped was on  August 6, 1945 on the city of Hiroshima. The second atomic bomb  (called fatman) dropped was on Nagasaki three days later.  The United States dropped these bombs on Japan in order to end  World War II.Then on August 14, 1945, the Japanese surrendered.he was ended  only 1 day after the second bomb was dropped. The bombs caused  Japan to surrender. Both a-bombs (atomic bombs) caused about  128,000 people to die and over 120, 000 people suffered from  radiation sickness and cancer.