Hello Lisagarmaise, Serotonin is to blame! Excessive release of 5HT(serotonin) from intestinal mucosa cells can cause diarrhea and nausea. Metformin stimulates these intestinal cells to produce increased levels of 5HT, as soon as 10-15 minutes after taking metformin. The good news is that most symptoms dissapear after taking metformin for 2-3 weeks.
Progesterone, hormone secreted by the female reproductive system that functions mainly to regulate the condition of the inner lining (endometrium) of the uterus. Progesterone is produced by the ovaries, placenta, and adrenal glands.
The corpus luteum secretes progesterone & other hormones to maintain early pregnancy which maintains the uterine lining during the first months of pregnancy. The corpus luteâ¦um in the ovary results from the release of an egg. It now produces progesterone to maintain the endometrium of the uterine walls. The corpus luteum is a yellow body. Before it released the egg, it was white and referred to as the corpus albicans (white body).