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Similar to heroin, oxycodone produces â along with pain management â a euphoric high caused by stimulation of the reward center of the brain. Oxycodone elevates levels of the neurotransmitter dopamine, which is considered the pleasure chemical of the brain. On the street, OxyContin is known as âOxy,â âOC,â âOxyCotton,â âHillbilly Heroin,â and âKickers,â and is often used if heroin or morphine is not available.
Long-Term Effects of OxyContin. Opiates have severe effects on the brain, and OxyContin is no different. Long-term effects include persistent vomiting and diarrhea caused by its action on the stomach.The stomach is unable to regulate itself properly, leading to these issues.piates have severe effects on the brain, and OxyContin is no different. Long-term effects include persistent vomiting and diarrhea caused by its action on the stomach.