The Cas9 nuclease and requirements for RNA-guided genome-editing. Cas9 is the nuclease guided by the crRNA and tracrRNA (or trans-activating crRNA) to cleave specific DNA sequences (Deltcheva et al.2011). A guide RNA (gRNA) can be designed to include a hairpin that mimics the tracrRNA-crRNA complex (Jinek et al. 2012).he Cas9 nuclease and requirements for RNA-guided genome-editing. Cas9 is the nuclease guided by the crRNA and tracrRNA (or trans-activating crRNA) to cleave specific DNA sequences (Deltcheva et al. 2011).
Solid Surface Bathroom Countertops: These countertops are made from synthetic materials, so they are manufactured in many colors and styles. The pros of solid surface countertops include the choices, strength and a non-porous surface that cleans up quickly.
These countertops are literally made from lava stone quarried from the site of ancient volcano eruptions. Most of the lava stone countertops currently being produced come from stone extracted from craters in Auvergne, France, but other sources are being developed as these bathroom and kitchen countertops grow in demand.Once the stone is mined, it is custom-cut for each individual order.hese countertops are literally made from lava stone quarried from the site of ancient volcano eruptions. Most of the lava stone countertops currently being produced come from stone extracted from craters in Auvergne, France, but other sources are being developed as these bathroom and kitchen countertops grow in demand.