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Normal (i.e. healthy) red bloods cells live about 120 days in the bloodstream, after which they die and are replaced by new ones. In some unhealthy conditions, for example in â¦ sickle cell anemia, red blood cells usually die about 10 times faster (after only 10 to 20 days).aking the world better, one answer at a time. Red blood cells last an average of 120 days in the bloodstream. When red blood cells age, they are removed by macrophages in the liver and spleen.
Ninety-nine percent of the blood cells floating in plasma are red blood cells, which carry oxygen from the lungs to the rest of the body and give blood its red color. The average life of a red blood cell is four months. The spleen continuously destroys millions of old red blood cells, recycling the iron to make new red cells. White blood cells, which are part of the immune system, and platelets, which help with blood clotting at a site of injury, also float in plasma.