DNA has a negative charge because of the phosphate ions in its chemical backbone.
Homeostatic regulation involves three parts or mechanisms: 1) the receptor, 2) the control center and 3) the effector. The receptor receives information that something in the environment is changing. The control center or integration center receives and processes information from the receptor.
The importance of homeostatic mechanisms to the well being of an organism is underscored by the consequences of their failure. For example, at body temperatures of 107&Acirc;&deg;F (42&Acirc;&deg;C), the negative feedback systems cease to function.