Doctor: Brown patches and spots on skin appear for many reasons â age, sun exposure, pregnancy, as a side effect of certain medi dications, freckles, moles, hormones, rashes, and dozens more. Commonly known as hyperpigmentation, and also called a melasma or a lentigo, a brown patch or spot on the skin is harmless yet disturbing to most people because of the way it looks.
There may be an increased risk of side effects on the kidneys if meloxicam is used with any of the following medicines: 1  ACE inhibitors, eg enalapril. 2  angiotensin II receptor antagonists, eg losartan. 3  ciclosporin. diuretics, eg furosemide.  tacrolimus.
SIDE EFFECTS WARNING: 1  Individuals who are allergic to NSAIDs may experience shortness of breath when given an NSAID. 2  New onset or worsening of high blood pressure (hypertension) may occur. 3  Meloxicam may cause fluid retention and swelling (edema).  Meloxicam may reduce kidney function. Therefore, it should not be used in people with severe kidney failure. It should be used cautiously in the elderly, people with heart failure, liver dysfunction, and those taking diuretics, ACE-inhibitors, or angiotensin II antagonists.