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A: Most lymph nodes are located in the head, neck, armpits and groin area, explains Mayo Clinic. There are hundreds of these nodes in the body located in other regions such as the joints, elbows and knees and around the lungs and bowels, states the American Cancer Society.
Approximately 600 lymph nodes are scattered throughout the human body. Lymph nodes can exist singly or in closely connected groups called chains, which are located in specific regions of your body. Whether they're single or clustered in chains, lymph nodes are connected to their neighbors by lymphatic vessels.