DNA has a negative charge because of the phosphate ions in its chemical backbone.
Homeostatic regulation involves three parts or mechanisms: 1) the receptor, 2) the control center and 3) the effector. The receptor receives information that something in the environment is changing. The control center or integration center receives and processes information from the receptor.
Temperature detection and regulation is of vital importance to any homeothermic organism. In order to maintain temperature homeostasis it is necessary for the autonomic nervous system to monitor small fluctuations in core body temperature and initiate counter measures to prevent temperature fluctuations beyond a tightly controlled set point.