DNA has a negative charge because of the phosphate ions in its chemical backbone.
Homeostatic regulation involves three parts or mechanisms: 1) the receptor, 2) the control center and 3) the effector. The receptor receives information that something in the environment is changing. The control center or integration center receives and processes information from the receptor.
Homeostasis is the process by which a nearly stable internal environment is maintained in the body so that cellular metabolic functions can proceed at maximum efficiency. Homeostasis is maintained by muscles or glands that are regulated by sensory information from the internal environment.