Doctor: Brown patches and spots on skin appear for many reasons â age, sun exposure, pregnancy, as a side effect of certain medi dications, freckles, moles, hormones, rashes, and dozens more. Commonly known as hyperpigmentation, and also called a melasma or a lentigo, a brown patch or spot on the skin is harmless yet disturbing to most people because of the way it looks.
There may be an increased risk of side effects on the kidneys if meloxicam is used with any of the following medicines: 1  ACE inhibitors, eg enalapril. 2  angiotensin II receptor antagonists, eg losartan. 3  ciclosporin. diuretics, eg furosemide.  tacrolimus.
Side effects. Meloxicam use can result in gastrointestinal toxicity and bleeding, headaches, rash, and very dark or black stool (a sign of intestinal bleeding). Like other NSAIDs, its use is associated with an increased risk of cardiovascular events such as heart attack and stroke.