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Though mostly water, the cytosol is full of proteins that control cell metabolism including signal transduction pathways, glycolysis, intracellular receptors, and transcription factors. Cytoplasm is a collective term for the cytosol plus the organelles suspended within the cytosol.
1. Cytosol is the intra-cellular fluid that is present inside the cells. On the other hand, cytoplasm. is that part of the cell which is contained within the entire cell membrane. 2. Cytosol comprises of a lot of water, dissolved ions, large water soluble molecules, smaller. minute molecules and proteins.nce the process of eukaryotes starts, the fluid is separated by the cell membrane from the organelles (mitochondrial matrix) and the other contents that float about in the cytosol. Cytosol is the part of the cytoplasm that is not held by any of the organelles in the cell.