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Lithium is a medicine that is used to treat mood disorders. Get advice on how it works. Lithium is a medicine that is used to treat mood disorders: depression where mood is severely low. bipolar affective disorder (manic depression) in which mood is excessively high on some occasions and very low on others.
Lithium salts have been used in medical practice for about 150 years. Lithium salts were first used to treat gout. It was noted in the 1880s that lithium was somewhat effective in the treatment of depression, and in the 1950s lithium was seen to improve the symptoms of bipolar disease.urpose. Lithium is commonly used to treat mania and bipolar depression (manic-depression or bipolar disorder). Less commonly, lithium is used to treat certain mood disorders, such as schizoaffective disorder and aggressive behavior and emotional instability in adults and children.