The genetic history of the British Isles is the subject of research within the larger field of human population genetics. It has developed in parallel with DNA testing technologies capable of identifying genetic similarities and differences between populations.he genetic history of the British Isles is the subject of research within the larger field of human population genetics. It has developed in parallel with DNA testing technologies capable of identifying genetic similarities and differences between populations.
Brittle diabetesâalso called labile diabetesâis a rare but serious form of the disease in which there are dramatic and often unpredictable fluctuations in blood sugar levels. Blood sugar naturally rises and falls throughout the day in response to meals, exercise and other factors.
It is well established that osteoporosis and diabetes are prevalent diseases with significant associated morbidity and mortality. The relationship between diabetes and bone disease is less well defined but recent data seem to suggest that diabetes and the complications associated with it can be detrimental to bone health. Furthermore, it appears that thiazolidinediones, medications used in the treatment of diabetes, can also cause bone loss and increase the risk of fracture. This article will review the relationship between diabetes and bone health. Copyright Â© 2011 John Wiley & Sons, Ltd. Osteoporosis is a skeletal disorder characterized by compromised bone strength predisposing to an increased risk of fractures 1. The global burden of osteoporosis is significant, with approximately 9 million new osteoporotic fractures worldwide in the year 2000 2. Many of these fractures are associated with significant morbidity and mortality. Diabetes is also an increasingly prevalent disease, with significant associated morbidity and mortality. The prevalence of diabetes for all age-groups is estimated to be 4.4% of the worldwide population by the year 2030 3.