DNA has a negative charge because of the phosphate ions in its chemical backbone.
Homeostatic regulation involves three parts or mechanisms: 1) the receptor, 2) the control center and 3) the effector. The receptor receives information that something in the environment is changing. The control center or integration center receives and processes information from the receptor.
1 Feedback regulation mechanisms are important to homeostasis. 2  Feedback regulation occurs when the response to a stimulus has an effect of some kind on the original stimulus. 3  The type of response (increase or decrease in the stimulus) determines what the feedback is called. The homeostatic balance of most organs and organ systems is controlled by hormones secreted from the pituitary gland, a part of the endocrine system. 2  When the cells in your body do not work correctly, homeostatic balance is disrupted. 3  Homeostatic imbalance may lead to a state of disease.