What is the name of the symbol placed at the beginning of each staff of a musical score that determines the range of notes represented on the staff? 9 . What is the musical term used to describe the interval relationship between all notes that share the same pitch name? 10 .
Methadone is commonly used to treat addiction to opiates (such as heroin). Taken once a day, methadone eases opiate withdrawal for 24 to 36 hours, decreasing the chance of relapse.
Methadone has an elimination half-life of 8 to 59 hours. Unlike other drugs, methadone has a wide bioavailability window varying from 40 to 99%. Up to 90% of methadone binds with blood plasma but after repetitive administration these number drastically change.