Of or pertaining to James the First, of England, or of his reign or times; especially, pertaining to a style of architecture and decoration popular in the time of James I.; as, Jacobean writers. Etymology: From L. Jacobus James.
ALS is a progressive, degenerative disease of the nervous system. It is one of a group of diseases, called motor neuron diseases (MND), in which specialized nerve cells that control movement of the voluntary muscles gradually cease functioning and die. Fasciculation is a sign of muscle irritability, as the normal action of the lower motor neuron on the muscle is impaired. 2  The sole involvement of lower motor neurons can be seen in a form of ALS called progressive muscular atrophy.
Muscle atrophy, or muscle wasting, results from loss of muscle tissue. Little or no physical exercise and a sedentary lifestyle are common causes of muscle atrophy, in this case called disuse atrophy.ther common causes of disuse atrophy include medical conditions that decrease mobility, such as rheumatoid arthritis (chronic autoimmune disease characterized by joint inflammation) or osteoarthritis (thinning and weakening of the bones), and injuries, such as broken bones and burns.