Mediator Variable vs Moderator Variable. There is often confusion among students concerning the difference between a mediator variable and a moderator variable. The explanation involves some concepts that haven't been introduced at this point but it can still be worthwhile to discuss these types of variables.n analysis of variance (ANOVA) terms, a moderator effect can be represented as an interaction between a major independent variable and a factor that specifies the appropriate conditions for its operation, that is, the effect of the major independent variable depends upon the value of the moderator variable.
The most common form of myelopathy in human, cervical spondylotic myelopathy (CSM), is caused by arthritic changes (spondylosis) of the cervical spine, which result in narrowing of the spinal canal (spinal stenosis) ultimately causing compression of the spinal cord.
Adrenomyeloneuropathy is a rare genetic disease that is a form of adrenoleukodystrophy. The disease affects the nerve cells in the spine and possibly the brain and the adrenal glands. The first symptoms are often trouble walking. Adrenomyeloneuropathy most often occurs in young men (20 to 40 years) but may begin anywhere between the ages of 20 and 50 years. Women may also be affected but with later and milder symptoms, or may be carriers of the disease, meaning that they do not show symptoms but can pass the genetic trait to their children. The disease has two main types: adrenomyeloneuropathy with cerebral involvement (both the spinal cord and brain are affected), and adrenomyeloneuropathy without cerebral involvement (only the spinal cord is affected).