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1 Symptoms and signs of leptospirosis are highly variable and range from no symptoms to nonspecific symptoms including high fever, chills, headache, abdominal symptoms to Weil's disease with organ dysfunction.  Definitive diagnosis is done by isolating the bacteria from the patient; serological tests are also available.
Humans can also contract Leptospirosis via direct contact with an infected rodentâs urine. A great variety of symptoms have been associated with the disease such as red eyes, jaundice, vomiting, chills and more.