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Symptoms. The most common symptoms associated with diabetes insipidus (DI) are extreme thirst and excessive urination. Some patients may drink as much as a full glass of fluids every 10 to 20 minutes.
Possible causes include congenital issues, trauma, metabolic conditions, kidney disease, adverse reactions to certain medications, or tumors of the pituitary gland. Despite the underlying cause of diabetes insipidus, the symptoms are the same. They include: 1  Increased thirst/urination (polydipsia/polyuria). 2  Dehydration. 3  Disorientation. 4  Seizures. 5  Diluted urine.