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Homocystinuria (HCU) is an inherited disorder of amino acid metabolism, caused by an enzymatic defect in a metabolic pathway that leads to increased levels of methionine.
Kuru is a progressive and fatal neurological disorder which reached epidemic proportions amongst the Fore People of Papua New Guinea in the 1950s. It is a prion disease that was caused by eating the brains of recently deceased people.uru Disease Prions. The brain disease Kuru is classified as a transmissible spongiform encephalopathy (TSE) also commonly referred to as a prion disease. The notable characteristic of such disorders is that they are caused by mis-folded prion proteins.