Science today isn't the same as the science 2000 years ago was but some principles remain the same. The human knowledge constantly grows but with more knowledge there comes even more mysteries and unsolved questions, so science is always going forward.
Causes. The most common cause of a cervical herniated nucleus pulposus is gradual degeneration of the disc, attenuation (weakening) of the posterior annulus fibrosis, and subsequent protrusion of the nucleus pulposus into the spinal canal causing compression of the nerve root.
Megacolon - Cause. 1  Congenital or aganglionic megacolon. 2  Medication. 3  Acquired megacolon, of which there are several possible causes... 4  Also called Hirschsprung's disease, it is a congenital disorder of the colon in which nerve cells of the myenteric plexus in its walls, also known as ganglion cells, are absent.