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Pathophysiology. The colonic mucosa is a self-renewing epithelium that is structured is a very tightly regulated balance between cell proliferation at the base of a crypt, maturation as colonocytes, migrate up the crypt, and extrusion of senescent and/or apoptotic cells from the upper crypt into the lumen.
background mucosa associated lymphoid tissue malt is scattered along mucosal linings in the human body and constitutes the most extensive component of human lymphoid tissuethese surfaces protect the body from an enormous quantity and variety of antigensolonic biopsy descending colon lymphoepithelial lesions are strongly associated with mucosa associated lymphoid tissue lymphomas malt lymphomas however they may appear in other types of lymphomas