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Gene mutation on the X chromosome is most common and also explains why (depending on nationality) some 7% of males, but less than 1% of females exhibit color blindness of some form. Males only have one X chromosome, whereas females have two.
Mutations cause changes in the genetic code that lead to genetic variation and the potential to develop disease. Gene mutations can be generally categorized into two types: point mutations and base-pair insertions or deletions. Point mutations are the most common type of gene mutation. Also called a base-pair substitution, this type of mutation changes a single nucleotide base pair.