Then follow this formula from Melton: 1  One to two hours before your workout, drink 15 to 20 ounces of water. 2  15 minutes before you begin, drink between 8 and 10 ounces of water. 3  During your workout, drink another 8 ounces every 15 minutes.
deÂ·acÂ·tiÂ·vate. tr.v. deÂ·acÂ·tiÂ·vatÂ·ed, deÂ·acÂ·tiÂ·vatÂ·ing, deÂ·acÂ·tiÂ·vates. 1. To render inactive or ineffective. 2. To inhibit, block, or disrupt the action of (an enzyme or other biological agent). 3. To remove from active military status.
Inactivation and closure is an intrinsic property of that type of calcium channel, and the channels do not REACTIVATE until the cell returns to being polarized once again. This inactivation is what limits the amount of calcium flux INTO the cell, which as mentioned in the other answer can be toxic to the cell.