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Lymphadenopathy is a condition where the lymph nodes, small round organs found all over the body, begin to swell, which could cause painful lump behind ear. The swelling is caused by accumulation of immune cells within the lymph node.
Mastoiditis occurs when ear infections cause infection in the mastoid bone. The mastoid bone can be found directly behind the ear. Mastoiditis causes the area behind the ear to swell and protrude out of the skin. The bump behind ear is accompanied with fever, ear pain, hearing loss and ear redness.