Anyone taking antimalarial drugs to prevent malaria who develops a fever or flu-like symptoms while taking the medicine or within 2-3 months after traveling to an area where malaria is common should call a physician immediately.
Treatment of knee pain depends on the cause of the knee pain. If you have been working on your knees all day then potentially rest and anti-inflammatories such as ibuprofen can help. If the cause is trauma and there is possible joint damage then you should seek medical attention.
Ice is absolutely essential for pain management in knee replacement surgery recovery. Ice can reduce pain in combination with medication, and with less severe pain, it can be used on its own.