E. coli and other facultative anaerobes constitute about 0.1% of gut flora, and fecalâoral transmission is the major route through which pathogenic strains of the bacterium cause disease.
Asthma symptoms in children ages 5-11. Common asthma signs and symptoms in children ages 5 to 11 include: 1  Coughing, particularly at night. 2  Wheezing. 3  Difficulty breathing. 4  Chest pain, tightness or discomfort. 5  Avoiding or losing interest in sports or physical activities.
Pathophysiology of asthma. Asthma is a common pulmonary condition defined by chronic inflammation of respiratory tubes, tightening of respiratory smooth muscle, and episodes of bronchoconstriction. The Centers for Disease Control and Prevention estimate that 1 in 11 children and 1 in 12 adults have asthma in the United States of America.