Holden /hold-en/ [2 sylls.] as a boys' name is pronounced HOHL-den. It is of Old English origin, and the meaning of Holden is deep valley. The hero of JD Salinger's novel The Catcher in the Rye is named Holden Caulfield.ariations. Holden is an uncommon given name for males but a very popular last name for both adults and children (#940 out of 150436, Top 1%).
Delta-9-tetrahydrocannabinol (Î´9-THC, THC) and delta-8-tetrahydrocannabinol (Î´8-THC), mimic the actions of anandamide and 2-arachidonoylglycerol, neurotransmitters produced naturally in the body. These cannabinoids produce the effects associated with cannabis by binding to the CB1 cannabinoid receptors in the brain.
CBD even has anti-psychoactive properties, making it capable of countering the euphoric effects of the psychoactive cannabinoid, tetrahydrocannabinol (THC). THC elicits a high by binding with the endocannabinoid systemâs cannabinoid 1 receptor (CB 1), but CBD blocks the receptor and prevents it from binding with THC. What Side Effects Does CBD Have? Derived from cannabis plants like hemp, cannabinoids such as CBD interact with your native endocannabinoid system. This central systemâs responsibility is to maintain the bodyâs homeostasis for a wide array of systems, including sleep, mood, anxiety, pain, appetite, and immune response.