Thyroid replacement hormones usually are well tolerated. Symptoms that occur during treatment are often due to toxic, elevated levels of thyroid hormones and resulting symptoms from hyperthyroidism.
Facts about the New Madrid Seismic Zone. The New Madrid Seismic Zone (NMSZ) is the most active seismic area in the United States east of the Rocky Mountains. The NMSZ is located in southeastern Missouri, northeastern Arkansas, western Tennessee, western Kentucky and southern Illinois.
The Madrid system for the international registration of marks (the Madrid system) established in 1891 functions under the Madrid Agreement (1891), and the Madrid Protocol (1989). It is administered by the International Bureau of WIPO located in Geneva, Switzerland.