Causes. Acute liver failure is most often caused by infectious agents or toxins, poor flow of fluids into the liver and surrounding tissues (perfusion), hypoxia (inability to breathe), drugs or chemicals that are destructive to the liver (hepatotoxic), and excess exposure to heat.
Definition of operate for English Language Learners. : 1  to function or behave in a proper or particular way. : 2  to use and control (something) : 3  to have control of (something, such as a business, department, program, etc.)
Define undertaking: the act of one who undertakes or engages in a project or business; the business of an undertaker â undertaking in a sentence the act of one who undertakes or engages in a project or business; the business of an undertaker; something undertaken : enterpriseâ¦ See the full definition since 1828