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Pathophysiology. The colonic mucosa is a self-renewing epithelium that is structured is a very tightly regulated balance between cell proliferation at the base of a crypt, maturation as colonocytes, migrate up the crypt, and extrusion of senescent and/or apoptotic cells from the upper crypt into the lumen.
the mucosa associated lymphoid tissue malt also called mucosa associated lymphatic tissue is a diffuse system of small concentrations of lymphoid tissue found in various sites of the body such as the gastrointestinal tract thyroid breast lung salivary glands eye and skin malt diffuse mucosa associated lymphatic tissue malt that is not organized as a separately macroscopically anatomically identifiable mass tissue or organ such as the aforementioned o malt is diffuse malt