1 Address risk factors that can lead to coronary heart disease and other heart problems. 2  These risk factors include high blood pressure, high blood cholesterol, overweight or obesity, diabetes, smoking, lack of physical activity, and depression and other emotional health concerns. 3  Adopt healthy lifestyle changes.
Primary sclerosing cholangitis is often diagnosed before symptoms appear when a routine blood test or an X-ray taken for an unrelated condition shows liver abnormalities. Early symptoms often include: 1  Fatigue. 2  Itching.
Signs and symptoms. Chikungunya is characterized by an abrupt onset of fever frequently accompanied by joint pain. Other common signs and symptoms include muscle pain, headache, nausea, fatigue and rash.The joint pain is often very debilitating, but usually lasts for a few days or may be prolonged to weeks. Other symptoms include muscle pain, headache, nausea, fatigue and rash. 2  Joint pain is often debilitating and can vary in duration. 3  The disease shares some clinical signs with dengue, and can be misdiagnosed in areas where dengue is common. 4  There is no cure for the disease.