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(3) renal â glutamine break down in proximal tubule (combines with H+ -> NH4+ and eliminated) CAUSES OF HYPERAMMONAEMIA. Overproduction of ammonia. Protein/ amino acid load. gastrointestinal hemorrhage. gastric bypass. multiple myeloma. allogeneic stem cell transplantation.
High levels of ammonia in the blood are dangerous and can cause symptoms such as confusion, sluggishness, and coma. High ammonia levels in the blood can result from acute liver failure. Cirrhosis of the liver and poor liver function can also cause high levels.