Organic acids are ubiquitous throughout the field of chemistry. Whether used as a solvent, a substrate, a strong acid, or in a catalytic amount as a Bronsted acid source, organic acids are as commonplace as glassware for the researcher.
In the equation, p 2 represents the frequency of the homozygous genotype AA, q 2 represents the frequency of the homozygous genotype aa, and 2pq represents the frequency of the heterozygous genotype Aa. In addition, the sum of the allele frequencies for all the alleles at the locus must be 1, so p + q = 1.
The allele frequency is distinct from the genotype frequency, although they are related, and allele frequencies can be calculated from genotype frequencies. In population genetics, allele frequencies are used to describe the amount of variation at a particular locus or across multiple loci.When considering the ensemble of allele frequencies for a large number of distinct loci, their distribution is called the allele frequency spectrum.n population genetics, allele frequencies are used to describe the amount of variation at a particular locus or across multiple loci. When considering the ensemble of allele frequencies for a large number of distinct loci, their distribution is called the allele frequency spectrum.