Medicines may be needed when symptoms of sinusitis are severe or do not improve. The goals of treatment with medicine are to: Treat the infection, which is usually caused by bacteria if your symptoms have lasted more than 7 to 10 days. Relieve pressure and pain caused by poor sinus drainage.
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In the event that any of these side effects do occur, they may require medical attention. You should check with your doctor immediately if any of these side effects occur when taking nitrofurantoin: 1  Changes in facial skin color. 2  chest pain. 3  chills. 4  cough. 5  fever. 6  general feeling of discomfort or illness.