Causes. Acute liver failure is most often caused by infectious agents or toxins, poor flow of fluids into the liver and surrounding tissues (perfusion), hypoxia (inability to breathe), drugs or chemicals that are destructive to the liver (hepatotoxic), and excess exposure to heat.
Definition of operate for English Language Learners. : 1  to function or behave in a proper or particular way. : 2  to use and control (something) : 3  to have control of (something, such as a business, department, program, etc.)
LINK / CITE ADD TO WORD LIST. noun. The definition of operations management is overseeing and controlling the day-to-day operations of a business that manufactures or sells goods or provides a service. Overseeing the daily operations of a data center is an example of operations management. Link/Cite.