I second that âwaterâ idea. Prunes are most effective if you eat them, and then drink one cup of water â that usually gives both your body, and the prunes enough water to soften your stools. If that doesnât work, wellâ¦ I really donât know what to say.
Abstract. The most common cystic fibrosis transmembrane conductance regulator (CFTR) mutant in cystic fibrosis patients, Î´F508 CFTR, is retained in the endoplasmic reticulum (ER) and is consequently degraded by the ubiquitin-proteasome pathway known as ER-associated degradation (ERAD).
Rough Endoplasmic Reticulum. The rough endoplasmic reticulum manufactures membranes and secretory proteins. The ribosomes attached to the rough ER synthesize proteins by the process of translation. In certain leukocytes (white blood cells), the rough ER produces antibodies. In pancreatic cells, the rough ER produces insulin.