1 Address risk factors that can lead to coronary heart disease and other heart problems. 2  These risk factors include high blood pressure, high blood cholesterol, overweight or obesity, diabetes, smoking, lack of physical activity, and depression and other emotional health concerns. 3  Adopt healthy lifestyle changes.
Primary sclerosing cholangitis is often diagnosed before symptoms appear when a routine blood test or an X-ray taken for an unrelated condition shows liver abnormalities. Early symptoms often include: 1  Fatigue. 2  Itching.
The symptoms of chronic bronchitis may include: 1  Persistent cough that produces clear, yellow, white, or green phlegm (for at least three months of the year, and for more than two years in a row) 2  Sometimes wheezing, sometimes breathlessness.  Feeling very tired.