Causes. Acute liver failure is most often caused by infectious agents or toxins, poor flow of fluids into the liver and surrounding tissues (perfusion), hypoxia (inability to breathe), drugs or chemicals that are destructive to the liver (hepatotoxic), and excess exposure to heat.
Definition of operate for English Language Learners. : 1  to function or behave in a proper or particular way. : 2  to use and control (something) : 3  to have control of (something, such as a business, department, program, etc.)
Operation can refer to medical surgery, a military campaign, or mathematical methods, such as multiplication and division. Operation comes from the Latin word opus (âworkâ) and can refer to a whole range of practical activities and work. In driver's education, you learn the proper operation of a motor vehicle.