I second that âwaterâ idea. Prunes are most effective if you eat them, and then drink one cup of water â that usually gives both your body, and the prunes enough water to soften your stools. If that doesnât work, wellâ¦ I really donât know what to say.
Abstract. The most common cystic fibrosis transmembrane conductance regulator (CFTR) mutant in cystic fibrosis patients, Î´F508 CFTR, is retained in the endoplasmic reticulum (ER) and is consequently degraded by the ubiquitin-proteasome pathway known as ER-associated degradation (ERAD).
Endoplasmic Reticulum. The endoplasmic reticulum is a multifold membranous structure within eukaryotic cells which plays a major role in the synthesis of the complex molecules required by the cell and the organism as a whole.xamples of protein synthesis by the rough endoplasmic reticulum are the proteins produced in secretory cells. These include the digestive enzymes produced in the stomach and the protein hormones like insulin produced in the pancreas.