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Pathophysiology. The colonic mucosa is a self-renewing epithelium that is structured is a very tightly regulated balance between cell proliferation at the base of a crypt, maturation as colonocytes, migrate up the crypt, and extrusion of senescent and/or apoptotic cells from the upper crypt into the lumen.
All sections of the colon looked normal except for the ascending colon (benign colonic mucosa with lymphoid follicle), the sigmoid (benign colonic mucoasa with lymphoid aggregate), and rectum (benign colonic mucosa with a focus of coagulative necrosis). What do all these mean.ll sections of the colon looked normal except for the ascending colon (benign colonic mucosa with lymphoid follicle), the sigmoid (benign colonic mucoasa with lymphoid aggregate), and rectum (benign colonic mucosa with a focus of coagulative necrosis). What do all these mean.