Sharif M et al. Serum hyaluronic acid level as a predictor of disease progression in osteoarthritis of the knee. Arthritis Rheum 38:760-767, 1995; Hochberg MC et al. Serum levels of insulin-like growth factor 1 in subjects with osteoarthritis of the knee. Arthritis Rheum 37:1177-1180, 1994
Stable isotopes of an element do not change over time. Atoms of unstable isotopes â also called radioisotopes--change into other elements over time through radioactive decay. Radioisotopes are used in many medical imaging and diagnostic procedures, with the isotope Tc-99m being used in 80 percent of tests.
It is the radioactive nature of these unstable atoms, usually referred to as 'radioisotopes', which gives them so many applications in modern science and technology. Their radioactivity means that they can be used as a tag to follow the movement of some material incorporating them.