Saudi-Arabia. 1  With the exception of the province of Asir on the western coast, Saudi Arabia has a desert climate characterized by extreme heat during the day, an abrupt drop in temperature at night, and very low annual rainfall. Because of the influence of a subtropical high-pressure system, there is considerable variation in temperature and humidity.
However, some people who have IgA deficiency experience recurrent respiratory tract infections, asthma, sinus infections, allergies and diarrhea. Selective IgA deficiency may also be found with autoimmune disease, in which your immune system attacks particular organs or tissues in your own body. Common autoimmune conditions found with IgA deficiency include rheumatoid arthritis, lupus and celiac disease.
Anti-IgE IgG autoantibodies have also been observed in SLE patients with lymphoadenopathy, articular involvement and anti-DNA antibodies (9). In addition, increased IgE serum levels were observed in children of mothers with lupus, regardless of the presence of allergic disease in the mothers (34).Another study showed elevated IgE levels in male SLE patients compared with female patients (35).o date, few studies have evaluated the IgE levels in SLE patients (4,6,7). High total IgE serum levels have been associated with disease activity and nephritis in adult SLE patients (4,12-15). However, to our knowledge, no studies have evaluated the association of IgE with juvenile SLE (JSLE).