Alport syndrome is caused by mutations in COL4A3, COL4A4, and COL4A5, all genes involved in collagen biosynthesis. Mutations in any of these genes prevent the proper production or assembly of the type IV collagen network, which is an important structural component of basement membranes in the kidney, inner ear, and eye.Basement membranes are thin, sheet-like structures that separate and support cells in many tissues.utations in any of these genes prevent the proper production or assembly of the type IV collagen network, which is an important structural component of basement membranes in the kidney, inner ear, and eye. Basement membranes are thin, sheet-like structures that separate and support cells in many tissues.
Company vision, values, norms, systems, symbols, language, assumptions, beliefs, and habits. Also slightly unhelpful. I feel the most important distinction to make here is that company culture is something that is pre-existing in your companyâs genetic code; itâs not something that employees bring with them. In fact, a company with just one employee â a company with no employees, if weâre being honest â still has a culture.
by Jim Grant | Corporate Culture, Culture Change, Organizational Culture, Organizational Culture Change, Organizational Leadership, Workplace Culture | 1 comment Tweet Asking a person to describe his or her workplace culture is like asking a fish to describe water. The fish isnât even aware of his environment because he is swimming in it and is completely oblivious to its presence or its importance, for that matter. Human beings are the same way about workplace culture. They are âswimming in itâ and are therefore oblivious it presence and really do have a tough time describing it even if asked a direct question about it.