perinatal. relating to the period shortly before and after birth; the actual time varies between species. The last 10 to 15% of the pregnancy before parturition to the end of a comparable period after birth would cover present usage of the term. perinatal mortality. the percentage of animals in the danger period which die, as a ratio of the total number exposed.
Normal Gene Tumor Suppressor Gene Is nicknamed the Guardian of the Genome.. Can arrest the cell cycle, trigger apoptosis or senescence, and repair DNA. Chromosome 17 Cell Survival Produces a protein called tumor protein p53, which regulates cell division.
The gene responsible for HGPS is called LMNA (pronounced âlamin-aâ). Within this gene there is a change in one piece of DNA that is responsible for Progeria. This type of gene change is called a point mutation. The LMNA gene makes a protein called Lamin A, which is an important protein for most cells of our bodies. Lamin A is found in the cell nucleus (the part of each cell that contains the DNA), and helps maintain the shape and function of the cell. The point mutation compromises that cell integrity, causing Progeria.