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Radiation therapy can have side effects, and these vary from person to person. The most common side-effects are: 1  Sunburn-type skin irritation of the targeted area (which may range from mild to intense). 2  Red, dry, tender, or itchy skin. 3  Breast heaviness. 4  Discoloration, redness, or a bruised appearance.
Side effects can happen any time during, immediately after or a few days or weeks after radiation therapy. Most side effects generally go away within a few weeks to 2 months of finishing treatment. But some side effects may continue after treatment is over because it takes time for healthy cells to recover from the effects of radiation therapy. Late side effects can happen months or years after treatment. If doses of radiation are high enough, some cells may not be able to repair themselves. As a result, some side effects may last a long time or be permanent. In general, the side effects of radiation therapy will depend on: the type of radiation therapy; the part of your body being treated