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1 Hormone. 2  can be either hydrophilic (polypeptide hormone) or lipophilic (steroid) biogenic amines can be either. 3  binds specific receptor on cell surface (hydrophilic hormones) or inside cell (lipophilic hormones). 4  lipophilic hormones bind carrier proteins to travel in circulation; hydrophilic hormones travel freely.efinitions. 1  Hormone. 2  can be either hydrophilic (polypeptide hormone) or lipophilic (steroid) biogenic amines can be either. 3  binds specific receptor on cell surface (hydrophilic hormones) or inside cell (lipophilic hormones).
1 They include the thyroid hormones and the hormones of the adrenal medulla (epinephrine and norepinephrine). These hormones are water soluble.  Peptide Hormones. These hormones consist of chains of amino acids that vary in size from 3 amino acids (TRH) to 191 amino acids (GH).