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Memory-like effects in brain reward pathway could contribute to drug addiction. The effects of nicotine upon brain regions involved in addiction mirror those of cocaine, according to new neuroscience research. A single 15-minute exposure to nicotine caused a long-term increase in the excitability of neurons involved in reward, according to a study published in The Journal of Neuroscience.
Supplying your brain with nicotine fixes the anxiety and the restlessness and irritability, but does not have that feeling reminiscent of afterglow. I can still get buzzed on nicotine, but it is a very mild kind of buzz, not an earth-shattering kind of buzz.