Oxalate is an end product of glyoxalate and glycerate metabolism. Humans have no enzyme capable of degrading oxalate, so it must be eliminated by the kidney. In tubular fluid, oxalate can combine with calcium to form calcium oxalate stones. In addition, high concentrations of oxalate may be toxic for renal cells.
Ellie Mae, Inc. is a software company that processes almost a quarter of U.S. mortgage applications. The services are based on a software as a service model (SaaS) that streamlines and automates the process of originating and funding new mortgage loans and facilitating regulatory compliance.
Barbara Bel Geddes (later Miss Ellie of Dallas) plays a young naÃ¯f who marries a rich control-freak named Smith Ohlrig. In the latter role, Ryan creates an ego-monster who bears an uncanny resemblance to billionaire Howard Hughesâwho happened to own RKO and was, in effect, the actorâs boss.