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Common causes for discharge are; 1  Sleeping. Sleep in your eyes usually isn't cause for alarm, but if you notice a difference in consistency, color and quantity of eye gunk, it could indicate an eye infection or disease.  Conjunctivitis.
According to Dr. Alan Kozarsky on WebMD, pink eye causes thick mucus in the eye after sleep, a burning sensation in the eye, and possibly blurred vision due to the excess mucus on the surface of the eye. 3 There are various types of eye inflammation that cause a thick discharge to appear in the eye and become crusty. Viral conjunctivitis.