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A stem cell transplant is used for treatment when: 1  Your body cannot make the blood cells it needs because your bone marrow or stem cells have failed. 2  Your bone marrow or blood cells have become diseased.3  In this case you need healthy stem cells to replace the diseased bone marrow/stem cells. Your body cannot make the blood cells it needs because your bone marrow or stem cells have failed. 2  Your bone marrow or blood cells have become diseased. 3  In this case you need healthy stem cells to replace the diseased bone marrow/stem cells.
A bone marrow transplant is a procedure that infuses healthy blood stem cells into your body to replace your damaged or diseased bone marrow. A bone marrow transplant is also called a stem cell transplant. A bone marrow transplant may be necessary if your bone marrow stops working and doesn't produce enough healthy blood cells. Bone marrow transplants may use cells from your own body (autologous transplant) or from a donor (allogeneic transplant). Mayo Clinic's approach.