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These infections are called âopportunisticâ because they take advantage of your weakened immune system, and they can cause devastating illnesses. OIs are signs of a declining immune system. Most life-threatening OIs occur when your. is below 200 cells/mm3. OIs are the most common cause of death for people with HIV/AIDS.
S â Syndrome. AIDS is a group of symptoms that can eventually result from an HIV infection. HIV can damage the bodyâs immune system over time, and cause ongoing inflammation in the body. When that happens, the body may not be able to fight off certain types of illnesses or cancer.