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October 26, 2007 By Uzma Haque, MD. Euflexxa is a highly purified hyaluronic acid, which is similar to the lubricating fluid present in joints. It is approved for treatment of moderate knee osteoarthritis to relieve symptoms such as pain and stiffness. As with any medication, its effectiveness is variable and thus difficult to predict in any particular individual.
Common side effects of Euflexxa include joint pain, back pain, pain in extremities, musculoskeletal pain, joint swelling, injection site pain, and arthritis. A dose of 2 mL of Euflexxa is injected intra-articularly into the affected knee at weekly intervals for three weeks, for a total of three injections. Euflexxa may interact with other drugs. Tell your doctor all medications and supplements you use. During pregnancy, Euflexxa should be used only if prescribed.