Substance-induced disorders include medical conditions that can be directly attributed to the use of a substance. These conditions include intoxication, withdrawal, substance-induced delirium, substance-induced psychosis, and substance-induced mood disorders.t is often thought that the main abused substances are illegal drugs and alcohol; however it is becoming more common that prescription drugs and tobacco are a prevalent problem. Substance-related disorders, including both substance dependence and substance abuse, can lead to large societal problems.
1 Net Profit Margin: This is often the equation used to determine an entire organizationâs profit margin. 2  Net profit margin is calculated by taking the companyâs total sales for a given time period, subtracting total expenses and then dividing that figure by total revenue.
Net profit margin is calculated by subtracting total cost from total sales and then dividing the result by total sales. For example, if a business has $1 million in total sales and its total costs equal $800,000, its net profit margin is $200,000 divided by $1 million or 20 percent.