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These infections are called âopportunisticâ because they take advantage of your weakened immune system, and they can cause devastating illnesses. OIs are signs of a declining immune system. Most life-threatening OIs occur when your. is below 200 cells/mm3. OIs are the most common cause of death for people with HIV/AIDS.
Definitions: 1  HIV-Human Immunodeficiency Virus, the virus that causes AIDS. 2  AIDS-Acquired Immunodeficiency Syndrome, the condition that results from HIV infection. 3  AIDS is distinguished from HIV by the presence of an opportunistic infection or a T-cell count of 200 or less. AIDS-Acquired Immunodeficiency Syndrome, the condition that results from HIV infection. 2  AIDS is distinguished from HIV by the presence of an opportunistic infection or a T-cell count of 200 or less.