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These infections are called âopportunisticâ because they take advantage of your weakened immune system, and they can cause devastating illnesses. OIs are signs of a declining immune system. Most life-threatening OIs occur when your. is below 200 cells/mm3. OIs are the most common cause of death for people with HIV/AIDS.
1 Combination tests have been developed that detect HIV antibody and the HIV antigen called the p24 antigen. 2  Levels of p24 antigen are typically high early in the course of infection. 3  A combination test may be performed to increase the likelihood that HIV infection is detected sooner after exposure occurs. Combination tests have been developed that detect HIV antibody and the HIV antigen called the p24 antigen. 2  Levels of p24 antigen are typically high early in the course of infection. 3  A combination test may be performed to increase the likelihood that HIV infection is detected sooner after exposure occurs.