1 A ligand is any molecule that binds to a specific site on a protein or other molecule. In this case, the estrogen hormone 17-beta-estradiol is the ligand, and the estrogen receptor is the protein.  Binding turns on, or activates, a hormone receptor.
A femoral nerve block is a type of regional anesthesia in which the femoral nerve, located in the groin area, is deadened to allow surgery in the leg or knee area.
What is a Nerve Block? A Nerve Block is a procedure performed by a pain management physician to anesthetize or numb a particular nerve in the body to treat certain forms of chronic pain. A Nerve Block involves the injection of a local anesthetic like Lidocaine or Bupivicaine onto a target nerve or group of nerves. An example of a therapeutic nerve block used to treat chronic pain is the Stellate Ganglion Block, performed in the front of the neck to treat Complex Regional Pain Syndrome (CRPS or RSD).