In general, infectious syphilis refers to the primary and secondary stages because syphilitic chancres, mucous patches, and condylomata lata are highly infectious lesions. Dry rashes, by exception, are typically noninfectious.
It appears to reduce pain primarily in the central nervous system by more than one mechanism, possibly in part by inhibiting a form of COX known as COX-3, although this is the subject of much debate. It is, therefore, considered to be a weak analgesic and does not possess anti-inflammatory properties. What this means to you is that acetaminophen is great for headaches, fever and minor aches and pains, but wonât reduce inflammation due to, say, a muscle sprain.
Itâs not a good idea to take it long-term, according to our medical advisors. Tylenol PM contains two medicationsâthe pain reliever acetaminophen and an antihistamine (diphenhydramine) to help with insomnia. High doses of acetaminophen can cause liver damage and the risk increases if you consume alcohol. Possible side effects of diphenhydramine include daytime sleepiness, confusion, constipation, dry mouth, and urinary retention and it can worsen your sleeping problems when taken too often.