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Memory-like effects in brain reward pathway could contribute to drug addiction. The effects of nicotine upon brain regions involved in addiction mirror those of cocaine, according to new neuroscience research. A single 15-minute exposure to nicotine caused a long-term increase in the excitability of neurons involved in reward, according to a study published in The Journal of Neuroscience.
Once within the bloodstream, nicotine may circulate around the body until it reaches the brain. This can occur in as little as 7 seconds. Once in the brain, it binds to and activates receptors called the cholinergic receptors. These cholinergic receptors are also abundant in other areas of the body such as the muscles, heart, adrenal glands and other vital organs.