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BCG is the only vaccine with this route of administration. Intradermal injection of BCG vaccine reduces the risk of neurovascular injury. Health workers say that BCG is the most difficult vaccine to administer due to the small size of newborns' arms. A short narrow needle (15 mm, 26 gauge) is needed for BCG vaccine.
Some of the other agents such as Parainfluenza and Adenovirus are part of the routine multivalent vaccinations generally given yearly to dogs. The intra-nasal Bordetella vaccine may produce immunity slightly faster than the injectable vaccine if the dog has never been previously vaccinated for Kennel Cough. It is generally assumed that the intranasal route of inoculation works the fastest in getting protective levels of immunity established.