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Stay on the safe side and avoid use. Underactive thyroid (hypothyroidism): There is a concern that propionyl-L-carnitine might make hypothyroidism worse or thyroid hormone treatment less effective. This is because a related chemical, L-carnitine, seems to interfere with thyroid hormone.
Severe hypothyroidism. When TSH is higher than 30 mlU/L and free T4 and T3 are low hypothyroidism is considered to be severe. Some common symptoms are fatigue, brain fog, feeling cold, hair and skin changes, puffiness of the face, muscle and joint aches and pains, low sex drive and depression.SH raises in proportion to degree of hypothyroidism. Increased TSH is earliest evidence of hypothyroidism and normally is sufficient to make the diagnosis. However, the measurement of free form of T4 and T3 thyroid hormones and thyroid antibodies are helpful to establish the cause of hypothyroidism.