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1 Hormone. 2  can be either hydrophilic (polypeptide hormone) or lipophilic (steroid) biogenic amines can be either. 3  binds specific receptor on cell surface (hydrophilic hormones) or inside cell (lipophilic hormones). 4  lipophilic hormones bind carrier proteins to travel in circulation; hydrophilic hormones travel freely.efinitions. 1  Hormone. 2  can be either hydrophilic (polypeptide hormone) or lipophilic (steroid) biogenic amines can be either. 3  binds specific receptor on cell surface (hydrophilic hormones) or inside cell (lipophilic hormones).
â¢ Lipophilic Hormones (Hydrophobic Hormones): â¢Hormones that are not soluble in aqueous medium, but soluble in lipid; â¢They can easily cross the cell membrane, â¢Thus, they can enter target cells and bind to intracellular receptors to carryout their action; â¢Examples: Thyroid hormones, Steroid hormones;