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Common causes for discharge are; 1  Sleeping. Sleep in your eyes usually isn't cause for alarm, but if you notice a difference in consistency, color and quantity of eye gunk, it could indicate an eye infection or disease.  Conjunctivitis.
Illness and disease: Measles, herpes, and diabetes may cause eye inflammation. Sexually transmitted diseases are also easily spread to the eye area. Inflammatory conditions such as lupus, arthritis and irritable bowel syndrome can also be causes.