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Radiation therapy can have side effects, and these vary from person to person. The most common side-effects are: 1  Sunburn-type skin irritation of the targeted area (which may range from mild to intense). 2  Red, dry, tender, or itchy skin. 3  Breast heaviness. 4  Discoloration, redness, or a bruised appearance.
While the goal of radiation is to target the cancer cells of a tumor, the healthy cells in and around the area can also be affected. Skin changes that can occur during or shortly after radiation treatment include: 1  dryness, 2  itching,