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Memory-like effects in brain reward pathway could contribute to drug addiction. The effects of nicotine upon brain regions involved in addiction mirror those of cocaine, according to new neuroscience research. A single 15-minute exposure to nicotine caused a long-term increase in the excitability of neurons involved in reward, according to a study published in The Journal of Neuroscience.
The Nicotine, although very similar to Acetylcholine, does not act exactly like the neurotransmitter and consequently causes the systems that it affects to function abnormally. The Nicotine causes a spontaneous release within the brain of other neurotransmitters that affect mood, appetite and memory. Additionally, many systems such as the respiratory and cardiovascular systems are sped up (4). Nicotine causes the pancreas to release glucose, causing smokers to be marginally hyperglycemic.