Histone lysine-specific demethylase 1 (LSD1) protein is involved in Sal-like protein 4 (SALL4)-mediated transcriptional repression in hematopoietic stem cells. Liu L, Souto J, Liao W, et al. J. Biol.
Melatonin may affect blood pressure. Caution is advised in people taking drugs, herbs, or supplements that affect blood pressure. Melatonin may affect blood sugar levels.Caution is advised in people with diabetes or low blood sugar and those taking drugs, herbs, or supplements that affect blood sugar.elatonin may affect blood pressure. Caution is advised in people taking drugs, herbs, or supplements that affect blood pressure. Melatonin may affect blood sugar levels.
For occasional sleep disturbance or jet lag, 3-5 mg should be taken one hour before bedtime. Melatonin should not be taken continuously for longer than four weeks. Higher doses or prolonged periods of use should only be attempted under medical supervision. Prolonged use of melatonin may interfere with sleep patterns.