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What is avascular necrosis? Avascular necrosis is a disease that results from the temporary or permanent loss of blood supply to the bone. When blood supply is cut off, the bone tissue dies and the bone collapses. If avascular necrosis happens near a joint, the joint surface may collapse. This condition may happen in any bone.
Avascular necrosis, also called aseptic necrosis, ischemic bone necrosis, or osteonecrosis, death of bone tissue caused by a lack of blood supply to the affected area. Avascular necrosis most commonly affects the epiphyses (ends) of the femur (thigh bone); other commonly affected bones include those of the upper arm, the shoulder, the knee, and the ankle. Avascular necrosis tends to occur in men more often than women and typically is diagnosed between ages 30 and 50.