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Phenylketonuria (commonly known as PKU) is an inherited disorder that increases the levels of a substance called phenylalanine in the blood. Phenylalanine is a building block of proteins (an amino acid) that is obtained through the diet. It is found in all proteins and in some artificial sweeteners.
Phenylketonuria is an inherited disorder. About one in every 15,000 infants born in the United States has PKU. People who are born with PKU are normal in every way except to stay healthy they must follow a strict diet which limits phenylalanine, a common part of most food. People with PKU have an inactive liver enzyme.henylketonuria is an inherited disorder. About one in every 15,000 infants born in the United States has PKU. People who are born with PKU are normal in every way except to stay healthy they must follow a strict diet which limits phenylalanine, a common part of most food. People with PKU have an inactive liver enzyme.