The hypodermis is the innermost and thickest layer of the skin. It invaginates into the dermis and is attached to the latter, immediately above it, by collagen and elastin fibres. It is essentially composed of a type of cells specialised in accumulating and storing fats, known as adipocytes.
Fatal familial insomnia Fatal familial insomnia (FFI) is a very rare, autosomal dominant inherited, disease of the brain. It is caused by a mutation in a protein called prion protein (PrP): asparagine-178 is replaced by aspartic acid.
Insomnia is a condition characterized by falling or staying asleep. There is no set definition of insomnia in terms of hours of sleep, and insomnia can have many forms. Some people with insomnia may have no trouble falling asleep but wake up too soon.Other people may have the opposite problem, or they have problems with falling asleep as well as staying asleep.here is no set definition of insomnia in terms of hours of sleep, and insomnia can have many forms. Some people with insomnia may have no trouble falling asleep but wake up too soon. Other people may have the opposite problem, or they have problems with falling asleep as well as staying asleep.