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These infections are called âopportunisticâ because they take advantage of your weakened immune system, and they can cause devastating illnesses. OIs are signs of a declining immune system. Most life-threatening OIs occur when your. is below 200 cells/mm3. OIs are the most common cause of death for people with HIV/AIDS.
Infections that take advantage of weakness in the immune defenses are called opportunistic.. The phrase opportunistic infection is often shortened to OI.. The rates of OIs have fallen dramatically since the introduction of antiretroviral therapies. However, OIs are still a problem, especially for people who have not been tested for HIV.