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1 Hormone. 2  can be either hydrophilic (polypeptide hormone) or lipophilic (steroid) biogenic amines can be either. 3  binds specific receptor on cell surface (hydrophilic hormones) or inside cell (lipophilic hormones). 4  lipophilic hormones bind carrier proteins to travel in circulation; hydrophilic hormones travel freely.efinitions. 1  Hormone. 2  can be either hydrophilic (polypeptide hormone) or lipophilic (steroid) biogenic amines can be either. 3  binds specific receptor on cell surface (hydrophilic hormones) or inside cell (lipophilic hormones).
These lipophilic hormones include the steroid hormones and thyroid hormones. Steroid hormones are secreted by only two endocrine glands: the adrenal cortex and the gonads (fig. 11.2). The gonads secrete sex steroids; the adrenal cortex secretes corticosteroids (including cortisol and aldosterone) and small amounts of sex steroids.