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By James Goodwin MD. The classic recommendation for initial treatment of temporal arteritis has been to commence with prednisone at a dosage of 40 to 80 mg/day, though 60 mg/day or above has been more commonly described than lower doses.f headache or other signs of temporal arteritis emerge during the course of polymyalgia rheumatica, however, it is important to increase the prednisone dosage to the levels recommended for initial treatment of temporal arteritis.
Therefore, prednisone should be initiated as early as possible in the treatment of RA usually with another DMARD. Treatment of the inflammation in RA should not exceed 10 mg/day and often may need to be given in daily divided doses (5 mg BID). Supplemental daily calcium at 800-1,000 mg/day and vitamin D at 400-800 units/day should always be initiated with treatment. Tapering of prednisone should be done slowly using 1 mg decrements every couple weeks to a month. One should not deem it a failure to hold the patient on the lowest effective dose of prednisone. pmid: