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Memory-like effects in brain reward pathway could contribute to drug addiction. The effects of nicotine upon brain regions involved in addiction mirror those of cocaine, according to new neuroscience research. A single 15-minute exposure to nicotine caused a long-term increase in the excitability of neurons involved in reward, according to a study published in The Journal of Neuroscience.
It is not that chewing tobacco put sugar into your blood stream; it is more of a drug interaction of the stimulant effect of nicotine that affects the blood sugar levels. Chewing tobacco cause the body to release its own stores of sugar and fat by a drug type of interaction. That is how it basically operated as an appetite suppressant, affecting the satiety centers of your hypothalamus. As far as for the sugar levels, nicotine in fact works much more efficiently than food.