Saudi-Arabia. 1  With the exception of the province of Asir on the western coast, Saudi Arabia has a desert climate characterized by extreme heat during the day, an abrupt drop in temperature at night, and very low annual rainfall. Because of the influence of a subtropical high-pressure system, there is considerable variation in temperature and humidity.
However, some people who have IgA deficiency experience recurrent respiratory tract infections, asthma, sinus infections, allergies and diarrhea. Selective IgA deficiency may also be found with autoimmune disease, in which your immune system attacks particular organs or tissues in your own body. Common autoimmune conditions found with IgA deficiency include rheumatoid arthritis, lupus and celiac disease.
IgA is a protein, called an antibody, that helps the body fight infections. IgA nephropathy occurs when too much of this protein is deposited in the kidneys. IgA builds up inside the small blood vessels of the kidney. Structures in the kidney called glomeruli become inflamed and damaged. The disorder can appear suddenly , or get worse slowly over many years (chronic glomerulonephritis). Risk factors include: 1  A personal or family history of IgA nephropathy or Henoch Schonlein purpura, a form of vasculitis that affects many parts of the body. 2  White or Asian ethnicity.