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A SNP is a variation of a single nucleotide between individuals. These polymorphisms can therefore be used to discern small differences both within a population and among different populations.
Noun. 1. SNP - (genetics) genetic variation in a DNA sequence that occurs when a single nucleotide in a genome is altered; SNPs are usually considered to be point mutations that have been evolutionarily successful enough to recur in a significant proportion of the population of a species. single nucleotide polymorphism.