Histone lysine-specific demethylase 1 (LSD1) protein is involved in Sal-like protein 4 (SALL4)-mediated transcriptional repression in hematopoietic stem cells. Liu L, Souto J, Liao W, et al. J. Biol.
Melatonin may affect blood pressure. Caution is advised in people taking drugs, herbs, or supplements that affect blood pressure. Melatonin may affect blood sugar levels.Caution is advised in people with diabetes or low blood sugar and those taking drugs, herbs, or supplements that affect blood sugar.elatonin may affect blood pressure. Caution is advised in people taking drugs, herbs, or supplements that affect blood pressure. Melatonin may affect blood sugar levels.
1 When to take: Depending on the severity of the sleep problem, take time-released melatonin 1 to 3 hours prior to the time you usually fall asleep. 2  Since time release melatonin only lasts for 3 â 4 hours, any need to shift sleep schedules more than 3 hours may require taking another pill in 3 or 4 hours. Since time release melatonin only lasts for 3 â 4 hours, any need to shift sleep schedules more than 3 hours may require taking another pill in 3 or 4 hours.