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A SNP is a variation of a single nucleotide between individuals. These polymorphisms can therefore be used to discern small differences both within a population and among different populations.
English. A single-nucleotide polymorphism (SNP, pronounced snip) is a DNA sequence variation occurring when a single nucleotide adenine (A), thymine (T), cytosine (C), or guanine (G]) in the genome (or other shared sequence) differs between members of a species or paired chromosomes in an individual.ithin a population, SNPs can be assigned a minor allele frequency â the lowest allele frequency at a locus that is observed in a particular population. This is simply the lesser of the two allele frequencies for single-nucleotide polymorphisms.