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Melatonin may affect blood pressure. Caution is advised in people taking drugs, herbs, or supplements that affect blood pressure. Melatonin may affect blood sugar levels.Caution is advised in people with diabetes or low blood sugar and those taking drugs, herbs, or supplements that affect blood sugar.elatonin may affect blood pressure. Caution is advised in people taking drugs, herbs, or supplements that affect blood pressure. Melatonin may affect blood sugar levels.
Although studies show that if you take more than 30 mg of melatonin per night it can cause a build up in your system, but it won't have any harmful effects necessarily, and after 30 mg it won't do anything more so its just a waste of the medication. Best Answer.