The hypodermis is the innermost and thickest layer of the skin. It invaginates into the dermis and is attached to the latter, immediately above it, by collagen and elastin fibres. It is essentially composed of a type of cells specialised in accumulating and storing fats, known as adipocytes.
Fatal familial insomnia Fatal familial insomnia (FFI) is a very rare, autosomal dominant inherited, disease of the brain. It is caused by a mutation in a protein called prion protein (PrP): asparagine-178 is replaced by aspartic acid.
A deadly prion disease: fatal familial insomnia. : An article from: Journal of Neuroscience Nursing $5.95: A gene with two faces - two fatal neurological diseases caused by the same gene mutation Creutzfeldt-Jakob disease and the extremely rare fatal familial insomnia are caused by an identical mutation on the gene that codes for the brain protein ... From Discover, 5/1/93 by Lori Oliwenstein Prion biology in transfusion medicine: implications for lab testing