perinatal. relating to the period shortly before and after birth; the actual time varies between species. The last 10 to 15% of the pregnancy before parturition to the end of a comparable period after birth would cover present usage of the term. perinatal mortality. the percentage of animals in the danger period which die, as a ratio of the total number exposed.
Normal Gene Tumor Suppressor Gene Is nicknamed the Guardian of the Genome.. Can arrest the cell cycle, trigger apoptosis or senescence, and repair DNA. Chromosome 17 Cell Survival Produces a protein called tumor protein p53, which regulates cell division.
The LMNA gene normally makes a protein called lamin A,which is an important protein for most cells of our bodies. Lamin A is foundin the cell nucleus (the part of each cell that contains the DNA) and helpsmaintain the shape and function of the cell. In Progeria, the LMNA mutation causes the gene to produce an abnormalLamin A protein called progerin. In children with Progeria, many cells in thebody â such as the blood vessels, skin, and bones â make progerin protein.As the children age, progerin builds up in these cells causing progressivedisease.