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1 Symptoms of anal psoriasis may include bleeding, pain during bowel movements, and excessive dryness and itching. 2  Buttocks crease: Psoriasis in the buttocks crease may be red and non-scaly or red with very heavy scales. 3  The skin in this area is not as fragile as that of the groin.
1 Hydroxychloroquine is the least likely to cause side effects. 2  Inderal: This high blood pressure medication worsens psoriasis in about 25 percent to 30 percent of patients with psoriasis who take it. 3  It is not known if all high blood pressure (beta blocker) medications worsen psoriasis, but they may have that potential.