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1 Hormone. 2  can be either hydrophilic (polypeptide hormone) or lipophilic (steroid) biogenic amines can be either. 3  binds specific receptor on cell surface (hydrophilic hormones) or inside cell (lipophilic hormones). 4  lipophilic hormones bind carrier proteins to travel in circulation; hydrophilic hormones travel freely.efinitions. 1  Hormone. 2  can be either hydrophilic (polypeptide hormone) or lipophilic (steroid) biogenic amines can be either. 3  binds specific receptor on cell surface (hydrophilic hormones) or inside cell (lipophilic hormones).
Cholesterol, bile acids, and steroid hormones. In humans cholesterol and cholesterol derivatives (steroid hormones, bile acids) are essential metabolites for the physiological integration of the body of the endocrine system, regulation of cell membrane processes, and adsorption of dietary lipids.teroid hormones are cholesterol derivatives in animals that are used for a broad range of signaling mechanisms. Cholesterol is hydroxylated and shortened (removing the the C6 hydrophobic side chain at position C21) to the C21 intermediates pregnenolone and progestagen.