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Calorie Breakdown. A slice of fast-food cheese pizza weighing approximately 103 g contains 272 calories, 33.56 g of carbohydrate, 12.27 g of protein, 9.8 g of fat, 4.35 g of saturated fat, 1.8 g of fiber, 551 mg of sodium and 22 mg of cholesterol, notes the U.S. Department of Agriculture's National Nutrient Database.
Your average plain cheese pizza has around 200 calories per slice or 1600 calories per pizza. You could probably eat one pizza a day as your only meal and manage to lose weight if that is all you ate.