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A stem cell transplant is used for treatment when: 1  Your body cannot make the blood cells it needs because your bone marrow or stem cells have failed. 2  Your bone marrow or blood cells have become diseased.3  In this case you need healthy stem cells to replace the diseased bone marrow/stem cells. Your body cannot make the blood cells it needs because your bone marrow or stem cells have failed. 2  Your bone marrow or blood cells have become diseased. 3  In this case you need healthy stem cells to replace the diseased bone marrow/stem cells.
This is known as a stem cell transplant. These infused stem cells can grow in the patientâs body and replace the patientâs own stem cells that were destroyed by the chemo-radiation therapy, resulting in a new line of white blood cells, red blood cells, or platelets that the patient will need to survive.he stem cells required for a stem cell transplant were historically collected from the bone marrow (spongy material inside large bones) or the circulating blood of patients or donors. Some patients, however, are unable to produce enough stem cells for a transplant or cannot find an appropriate donor.