The cerebral cortex is the part of the brain that most strongly distinguishes mammals. In non-mammalian vertebrates, the surface of the cerebrum is lined with a comparatively simple three-layered structure called the pallium.he brain is the most complex organ in a vertebrate's body. In a typical human, the cerebral cortex (the largest part) is estimated to contain 15â33 billion neurons, each connected by synapses to several thousand other neurons.
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