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In the beginning....there was bacterial infection. That is to say, the original theory about the cause of prostatitis was that it is caused by bacterial infection. Now, of course, we know that some prostatitis has nothing, or little, to do with bacteria.
Causes and Risk Factors. Bacterial prostatitis usually occurs when urine infected with bacteria flows backward through the ducts connecting the urethra and prostate gland. This is most common during or just after a urinary tract infection.