The hypodermis is the innermost and thickest layer of the skin. It invaginates into the dermis and is attached to the latter, immediately above it, by collagen and elastin fibres. It is essentially composed of a type of cells specialised in accumulating and storing fats, known as adipocytes.
Fatal familial insomnia Fatal familial insomnia (FFI) is a very rare, autosomal dominant inherited, disease of the brain. It is caused by a mutation in a protein called prion protein (PrP): asparagine-178 is replaced by aspartic acid.
Familial Periodic Paralysis. Familial periodic paralysis is a rare autosomal dominant condition with considerable variation in penetrance characterized by episodes of flaccid paralysis with loss of deep tendon reflexes and failure of muscle to respond to electrical stimulation.