perinatal. relating to the period shortly before and after birth; the actual time varies between species. The last 10 to 15% of the pregnancy before parturition to the end of a comparable period after birth would cover present usage of the term. perinatal mortality. the percentage of animals in the danger period which die, as a ratio of the total number exposed.
Normal Gene Tumor Suppressor Gene Is nicknamed the Guardian of the Genome.. Can arrest the cell cycle, trigger apoptosis or senescence, and repair DNA. Chromosome 17 Cell Survival Produces a protein called tumor protein p53, which regulates cell division.
Oncogenes are mutated genes whose PRESENCE can stimulate the development of cancer. When oncogenes arise in normal cells, they can contribute to the development of cancer by telling cells to make proteins that stimulate excessive cell growth and division. Oncogenes are gain of function genes. few important tumor-suppressor genes: 1  p53: a transcription factor that regulates cell division and cell death. 2  Rb: alters the activity of transcription factors and therefore controls cell division. 3  APC: controls the availability of a transcription factor.