The impact of a moderate to severe brain injury depends on the following: 1  Severity of initial injury. 2  Rate/completeness of physiological recovery. 3  Functions affected.  Meaning of dysfunction to the 1  individual. Resources available to aid recovery.  Areas of function not affected by TBI.
In humans, administration of histrelin acetate results in an initial increase in circulating levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), leading to a transient increase in concentration of gonadal steroids (testosterone and dihydrotestosterone in males); however, continuous administration of histrelin acetate results in decreased levels of LH and FSH due to a reversible down-regulation of the GnRH receptors in the pituitary gland and desensitization ...
How does it work? Periactin tablets contain the active ingredient cyproheptadine, which is a type of medicine called a sedating antihistamine. Histamine is a substance produced by the body as part of its defence mechanisms. It is stored in cells called mast cells, in almost all tissues of the body.