Xylitol is safe for humans, but is EXTREMELY toxic to dogs. Even small amounts of xylitol can result in hypoglycemia, seizures, liver failure, or even death in dogs. Symptoms of xylitol consumption appear within 15-30 minutes of consumption, and include vomiting, lethargy, incoordination, termors, seizures, and coma.
A Guide to the TPMT Lab Test. written by: angiem1981â¢edited by: Diana Cooperâ¢updated: 7/5/2011. The TPMT lab test, or the Thiopurine methyltransferase test, is a blood test used to check levels of the enzyme thiopurine before beginning certain therapies.This test can indicate whether or not thiopurine drugs will be an effective and safe treatment for the patient.slide 1 of 6. Guide to the TPMT Lab Test. written by: angiem1981â¢edited by: Diana Cooperâ¢updated: 7/5/2011. The TPMT lab test, or the Thiopurine methyltransferase test, is a blood test used to check levels of the enzyme thiopurine before beginning certain therapies.
TPMT. TPMT, also known as Thiopurine S-methyltransferase, is an enzyme that determines the level of 6-MMP as well as 6- TGN which are metabolites that are responsible for the potential toxicity and therapeutic aspect of thiopurine medications such as 6-MP, Azathioprine, and Imuran. [2] Thus, it is imperative that blood counts be regular tested when taking thiopurine drugs. 2  Use of thiopurines will affect the results of TPMT enzyme testing. 3  The test should be conducted PRIOR to commencing use of the drug.