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A SNP is a variation of a single nucleotide between individuals. These polymorphisms can therefore be used to discern small differences both within a population and among different populations.
What are single nucleotide polymorphisms (SNPs)? Single nucleotide polymorphisms, frequently called SNPs (pronounced âsnipsâ), are the most common type of genetic variation among people. Each SNP represents a difference in a single DNA building block, called a nucleotide. For example, a SNP may replace the nucleotide cytosine (C) with the nucleotide thymine (T) in a certain stretch of DNA. SNPs occur normally throughout a personâs DNA. They occur once in every 300 nucleotides on average, which means there are roughly 10 million SNPs in the human genome.