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A SNP is a variation of a single nucleotide between individuals. These polymorphisms can therefore be used to discern small differences both within a population and among different populations.
Applications of SNPs[edit] 1  Association studies can determine whether a genetic variant is associated with a disease or trait.  A tag SNP is a representative single-nucleotide polymorphism (SNP's) in a region of the genome with high linkage disequilibrium (the non-random association of alleles at two or more loci).