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Memory-like effects in brain reward pathway could contribute to drug addiction. The effects of nicotine upon brain regions involved in addiction mirror those of cocaine, according to new neuroscience research. A single 15-minute exposure to nicotine caused a long-term increase in the excitability of neurons involved in reward, according to a study published in The Journal of Neuroscience.
6.3.1 The neurobiology of the positive reinforcing properties of nicotine. The pleasant and rewarding effects of nicotine reinforce smoking and other forms of tobacco use.1 The neurobiology of nicotine's rewarding effects is only partially understood.