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1. ADH is synthesized in the hypothalamus while aldosterone is made in the adrenal cortex. 2. ADH conserves water directly through its reabsorption while aldosterone conserves water indirectly through the reabsorption of sodium.hese processes can be carried out by these two hormones. ADH is completely known as the antidiuretic hormone. It is also identified as AVP or arginine vasopressin or simply vasopressin. Basically, the difference between the two is regarding the mechanism of action.
Reabsorption of Na leads to reabsorption of water due to osmosis. ADH is synthesized in the hypothalamus and secreted by the posterior pituitary. While aldosterone is a steroid hormone secreted by the adrenal cortex of the adrenal gland and is a part of the renin-angiotension converting system.ADH is mainly responsible for maintaining the concentration of Na. thought they both acted on the kidneys to increase reabsorption of water and sodium ions into the blood and that the water reabsoprtion caused sodium reabsorption due to a concentration gradient. Help im confusedd=(Also would high blood pressure stop ADH... show more What is the difference between ADH and Aldosterone?