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Memory-like effects in brain reward pathway could contribute to drug addiction. The effects of nicotine upon brain regions involved in addiction mirror those of cocaine, according to new neuroscience research. A single 15-minute exposure to nicotine caused a long-term increase in the excitability of neurons involved in reward, according to a study published in The Journal of Neuroscience.
Nicotine changes the levels of certain brain chemicals -- particularly dopamine, which is famous for making you feel good and dulling pain. Because the nicotine in one cigarette doesn't stay around forever, you get the urge for another cigarette. However, your brain starts to adjust to those extra surges of dopamine.