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What is avascular necrosis? Avascular necrosis is a disease that results from the temporary or permanent loss of blood supply to the bone. When blood supply is cut off, the bone tissue dies and the bone collapses. If avascular necrosis happens near a joint, the joint surface may collapse. This condition may happen in any bone.
Avascular necrosis (AVN) is a disease that may affect several different bones as a result of temporary or. permanent loss of the blood supply to these bones. The femoral head is most commonly affected by this. disease. Usually, the patients are in their third, fourth or fifth decade of life at the time of diagnose. Initially, patients are asymptomatic, but, in time, AVN leads to joint destruction, requiring surgical. treatment and, in latter stages, total hip replacement.