The impact of a moderate to severe brain injury depends on the following: 1  Severity of initial injury. 2  Rate/completeness of physiological recovery. 3  Functions affected.  Meaning of dysfunction to the 1  individual. Resources available to aid recovery.  Areas of function not affected by TBI.
In humans, administration of histrelin acetate results in an initial increase in circulating levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), leading to a transient increase in concentration of gonadal steroids (testosterone and dihydrotestosterone in males); however, continuous administration of histrelin acetate results in decreased levels of LH and FSH due to a reversible down-regulation of the GnRH receptors in the pituitary gland and desensitization ...
Histamine is the primary effector substance released by the mast cell in response to an allergen. Antihistamines block H1 (histamine, type 1) receptors found on blood vessel endothelial cells and smooth muscle cells.he use of antihistamines to treat hayfever will also help to relieve asthma and reduce the severity of its symptoms. Antihistamines are available in tablet, nasal spray, cream, and eye drop form. The eye drops are useful for the red and itchy eyes often caused by airborne allergens like pollen.