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Drug-induced hypothyroidism may be caused by: 1  Drugs used for hyperthyroidism (overactive thyroid), such as propylthiouracil (PTU), radioactive iodine, potassium iodide, and methimazole. 2  Treatment with lithium or iodides in certain people.
L-thyroxine or Levothyroxine (Thyroid hormone, or T4). The most common medicine prescribed for the treatment of hypothyroidism is L-thyroxine, commonly known as the principal thyroid hormone or T4 (levothyroxine). The thyroxine provided in tablet form is identical to the thyroxine made by your own thyroid.