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Itâs not entirely clear why the length of acquired protection varies with different vaccines. A single dose of some vaccines provides lifelong immunity, while others require an additional dose (boosters) in order to maintain immunity.tâs not entirely clear why the length of acquired protection varies with different vaccines. A single dose of some vaccines provides lifelong immunity, while others require an additional dose (boosters) in order to maintain immunity.
The hepatitis B vaccine is given to protect people from getting the infection. In response to the vaccine, the body develops antibodies against hepatitis B virus (HBV). This response is known as active immunity.The hepatitis B vaccine is given as a series of 2, 3, or 4 shots (injection) in the upper arm or leg to provide long-lasting immunity.All babies need three doses: 1  The time between the first and second shot should be at least 1 month.he hepatitis B vaccine is given to protect people from getting the infection. In response to the vaccine, the body develops antibodies against hepatitis B virus (HBV). This response is known as active immunity.