Much scholarly and judicial attention has been dedicated to deciphering the Privileges or Immunities Clause of the Fourteenth Amendment, which states: âNo State shall make or enforce any law which shall abridge the privileges or immunities of citizens of the United States.â.
In the process of intramembranous ossification the formation of bone within CT, WHAT cells first aggregate in the vicinity of blood vessels and differentiate into osteoblast cells, which begin to synthesize and secrete the components of the matrix.
The observation that prostate cancer metastasis to bone is associated with increased osteoblast activity is supported by the finding that serum levels of markers of osteoblast proliferation, such as bone-specific alkaline phosphatase, are increased in patients with metastatic prostate cancer.