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Quick Answer. High PSA levels may indicate prostate cancer, prostatitis or an enlarged prostate, states WebMD. PSA levels in men naturally increase with age. In most cases, a PSA level under 4 nanograms per milliliter is considered normal, and men with this result have a low chance of prostate cancer. Continue Reading.
Answer: PSA levels do increase with age, in fact there have been age adjustments made to PSA levels that take this into account. The reason they go up as you age is not related to prostate cancer actually, but to a disease called benign prostatic hyperplasia or BPH.o therefore, men that get older typically have higher PSA levels. So the PSA age change is indeed a true one for most men as they age. The question of how often you should have your PSA level done really depends upon your age.