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Dependency, or addiction, is the most common of long-term heroin effects. Heroin is often considered the most addictive of all legal and illegal substances that are commonly abused for their mind-altering effects.
Morphine and Heroin Side Effects. The physical and psychological side effects of using heroin or morphine are quite strong. Some may experience anxiety or paranoia while others experience extreme fatigue and sedation. âPinnedâ pupils and double or blurred vision are common while under the influence of either drug.