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The more muscle a person has, the more creatinine they produce. Levels of creatinine in the blood reflect both the amount of muscle a person has and their amount of kidney function. Most men with normal kidney function have approximately 0.6 to 1.2 milligrams/deciliters (mg/dL) of creatinine. Most women with normal kidney function have between 0.5 to 1.1 mg/dL of creatinine. Women usually have lower creatinine levels than men because women, on average, have less muscle than men. Other factors that may affect the level of creatinine in the blood include body size, activity level and medications.
High creatinine means that the concentration of creatinine in the blood is higher than the normal range and this condition lasts for quite long time. The normal creatinine for men is 0.7-1.2 and it is 0.5-1.0 for women. Creatinine in the blood mainly comes from metabolism of muscles and meat products we eat. That is why men have higher creatinine then women because they usually have more muscle masses. When creatinine is produced, it will be released into the blood.