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Itâs not entirely clear why the length of acquired protection varies with different vaccines. A single dose of some vaccines provides lifelong immunity, while others require an additional dose (boosters) in order to maintain immunity.tâs not entirely clear why the length of acquired protection varies with different vaccines. A single dose of some vaccines provides lifelong immunity, while others require an additional dose (boosters) in order to maintain immunity.
A booster dose is usually given 6 to 12 months after the first dose. This provides long-term protection against the disease. A further booster may be needed after 20 years if you are still at risk of contracting the virus. This vaccine only provides protection against hepatitis caused by the hepatitis A virus.