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The sciatic nerve is the longest and largest nerve in the body; it measures three-quarters of an inch in diameter. It originates in the sacral plexus; a network of nerves in the low back (lumbosacral spine). The lumbosacral spine refers to the lumbar spine and the sacrum combined.he sciatic nerve starts in your low back, which is called your lumbar spine. The nerve roots are at the L4 and L5 vertebrae (the 'L' means lumbar, and the numbers indicate the level of the vertebraâwhere it is in your back). The sciatic nerve also travels through your pelvic region (sacrum).
The sciatic nerve. The sciatic nerve begins in the lumbar (lower back) region of the spine, specifically at the L4 and L5 levels. The nerve exits the spinal canal through two openings in the sacral (pelvic) spine, extending through the length of the legs. The sciatic nerve is the widest nerve of all the millions in the body, and it is also the longest nerve, which means it innervates more areas than any other nerve. Since the sciatic nerve begins in the lower back, but travels all the way to the toes, sciatic nerve pain can extend to the following areas: