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Very rarely, eye twitching may be a sign of certain brain and nervous system disorders. When it is, it's almost always accompanied by other signs and symptoms. Brain and nervous system disorders that can cause eye twitching include: Bell's palsy.
School of Medicine, Family Medicine answered. Eye twitching is causes blepharospasm. There are many causes of eye twitching. The common ones are alcohol, caffeine, fatigue, lack of sleep, physical exertion, smoking, stress, and irritation to the eye or eyelid. Chronic causes include inflamed eyelids, dry eyes, light sensitivity, and pink eye.