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Quick Answer. High PSA levels may indicate prostate cancer, prostatitis or an enlarged prostate, states WebMD. PSA levels in men naturally increase with age. In most cases, a PSA level under 4 nanograms per milliliter is considered normal, and men with this result have a low chance of prostate cancer. Continue Reading.
Welcome to the board! Several things are well-known for making the PSA level go up or down, and most of the time the PSA level changes it is not due to prostate cancer! Let's start there - with prostate cancer. Prostate cells make PSA, and that does not stop when the cells become cancerous. The reason PSA is a clue to possible prostate cancer is that a lot more PSA gets into the blood, where a blood test can detect it, when there is cancer.