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Itâs not entirely clear why the length of acquired protection varies with different vaccines. A single dose of some vaccines provides lifelong immunity, while others require an additional dose (boosters) in order to maintain immunity.tâs not entirely clear why the length of acquired protection varies with different vaccines. A single dose of some vaccines provides lifelong immunity, while others require an additional dose (boosters) in order to maintain immunity.
If you have been vaccinated previously with one of the currently licensed vaccines, you will still need two booster doses of rabies vaccine. The first dose should be given as soon as possible and the second dose three days later.