Inbreeding depression is the reduced biological fitness in a given population as a result of inbreeding, or breeding of related individuals. Population biological fitness refers to an organism's ability to survive and perpetuate its genetic material.
A âmicro entity,â as defined in 35 U.S.C. Â§ 123, is a patent applicant who meets the definition of a âsmall entityâ in addition to: (1) not being named on more than four previously-filed, U.S. non-provisional applications; and (2) not having gross income exceeding three times the median U.S. household income for the preceding calendar year in which the applicable fee is being paid.
1 First Tier Entity is any party that enters into a written agreement to provide administrative services or health care services.  Downstream Entity is any party that enters into a written arrangement with persons or entities below the level of the arrangement between our organization and the first tier entity. These written arrangements continue down to the level of the ultimate provider of both health and administrative services.