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What Can I Do if my HDL Cholesterol Level Is Low? If your HDL is low, you can take several steps to boost your HDL level and reduce your heart disease risk: Exercise. Aerobic exercise for 30 to 60 minutes on most days of the week can help pump up HDL. Quit smoking. Tobacco smoke lowers HDL, and quitting can increase HDL levels. Keep a healthy weight.
1 The medications fenofibrate (Lofibra, Tricor) and gemfibrozil (Lopid) can help increase your HDL cholesterol level. 2  Statins. 3  Statins block a substance your liver needs to make cholesterol. 4  This reduces cholesterol in your liver cells, which causes your liver to remove cholesterol from your blood.ven small changes to your daily habits can help you meet your HDL target. 1  Don't smoke. 2  If you smoke, quit. 3  Quitting smoking can increase your HDL cholesterol by up to 10 percent.