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Itâs not entirely clear why the length of acquired protection varies with different vaccines. A single dose of some vaccines provides lifelong immunity, while others require an additional dose (boosters) in order to maintain immunity.tâs not entirely clear why the length of acquired protection varies with different vaccines. A single dose of some vaccines provides lifelong immunity, while others require an additional dose (boosters) in order to maintain immunity.
How the rabies vaccine is given. The rabies vaccination is given as injections into your upper arm. You'll need three doses of the vaccine. The second dose is given seven days after the first. The third dose is given 14 or 21 days after the second. If you're planning to travel to an area where rabies is found, you should complete the full course of three doses before your departure.