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Itâs not entirely clear why the length of acquired protection varies with different vaccines. A single dose of some vaccines provides lifelong immunity, while others require an additional dose (boosters) in order to maintain immunity.tâs not entirely clear why the length of acquired protection varies with different vaccines. A single dose of some vaccines provides lifelong immunity, while others require an additional dose (boosters) in order to maintain immunity.
The hepatitis B vaccine protects against hepatitis B. It is administered in one primary dose and two booster doses to healthy adults 20 years and older and to healthy children and young adults 18 months to 20 years old.