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Short-Term Effects of Heroin. Often injected, the immediate effects of heroin are to modulate pain perception. As a street drug, dosing is impossible to fully control, and the side effects of decreased heart rate and breathing pose immense risk to users.
The long-term effects of heroin use on health can include: 1  dependence. 2  constipation. 3  menstrual irregularity and infertility in women. 4  loss of sex drive in men. 5  intense sadness. 6  cognitive impairment. 7  tetanus. 8  damage to heart, lungs, liver and brain.ow heroin affects a person depends on many things including their size, weight and health, also whether the person is used to taking it and whether other drugs are taken around the same time. The effects of any drug also depend on the amount taken.