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Latanoprost was the first prostaglandin to be approved as first-line treatment for elevated eye pressure. Three newer prostaglandins are travoprost (Travatan), bimatoprost (Lumigan),and tafluprost (Zioptan). These drugs are used to reduce eye pressure in patients with open-angle glaucoma and high ocular pressure. Side effects include itching, redness, and burning during administration. Muscle and joint pain may also occur.
The whole family of NSAIDS (non-steroidal anti-inflammatory drugs) can cause side effects that impact the eyes including cataracts, dry eyes, and retinal hemorrhages that may result from long term use. These include ibuprofin (Advil, Motrin, Bayer, Aleve, aspirin, flurbiprofen, ketoprofen and naproxen sodium.