Inbreeding depression is the reduced biological fitness in a given population as a result of inbreeding, or breeding of related individuals. Population biological fitness refers to an organism's ability to survive and perpetuate its genetic material.
A âmicro entity,â as defined in 35 U.S.C. Â§ 123, is a patent applicant who meets the definition of a âsmall entityâ in addition to: (1) not being named on more than four previously-filed, U.S. non-provisional applications; and (2) not having gross income exceeding three times the median U.S. household income for the preceding calendar year in which the applicable fee is being paid.
Downstream Entity is any party that enters into a written. arrangement, acceptable to CMS, with persons or entities. involved with the MA benefit or Part D benefit, below the. level of the arrangement between an MA organization or. applicant or a Part D plan sponsor or applicant and a First Tier.