SNAREs are integral membrane proteins (v-SNAREs on vesicles, t-SNAREs on the target organelles) and are thought to provide specificity to the fusion process1â5. It has been suggested that Sec17p and SeclSp bind to v-SNARE/t-SNARE complexes and mediate the membrane fusion event1â3.
In 2015, 4,976 people died in motorcycle crashes, up 8.3 percent from 4,594 in 2014, according to the National Highway Traffic Safety Administration (NHTSA). In 2014, motorcyclists were 27 times more likely than passenger car occupants to die in a crash per vehicle mile traveled, and almost five times more likely to be injured.
New preliminary 2016 data shared Wednesday from the National Safety Council estimates that as many as 40,000 people died in motor vehicles crashes last year, a 6% rise from 2015. If those numbers bear out, it would be a 14% increase in deaths since 2014, the biggest two-year jump in more than five decades. It also means that 2016 may have been the deadliest year on U.S. roads since 2007, the NSC says. Crashes result in the very real cost of human life.