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Another cause of encephalitis under study is encephalitis believed to be caused by an autoantibody attack on subunits of brain N-methyl-d-aspartate (NMDA) glutamate receptors. The autoantibodies are termed anti-NMDA receptor antibodies, and the disease is termed NMDA receptor encephalitis, first identified in 2007.
Signs and Symptoms. Symptoms of acute disseminated encephalomyelitis, or ADEM, are similar to multiple sclerosis. As a result, the disease is often misdiagnosed as a severe attack of multiple sclerosis. There are key differences, however, between the symptoms of ADEM and MS, which can be recognized by a neurologist. Initial symptoms of ADEM occur quickly and intensely as a single, short-lived attack, though some children experience recurrent episodes over a period of months. Symptoms may include: Fatigue; Fever; Headache; Nausea; Vomiting