Several reports demonstrate unexplained consequences of mutations on the expression of the different dystrophin isoforms and their balance. The most prominent example is found in some cases of X-linked dilated cardiomyopathy (XLDC).
In particular, calcitonin has the ability to decrease blood calcium levels at least in part by effects on two well-studied target organs: 1  Bone: Calcitonin suppresses resorption of bone by inhibiting the activity of osteoclasts, a cell type that digests bone matrix, releasing calcium and phosphorus into blood.
Calcitonin has opposite effects to those of PTH in bone andkidney. Finally, 1Î±,25-dihydroxy-Vitamin D stimulates calcium absorption in thegut, and has effects in bone and kidney as well.The key to calcium homeostasis is the amount of calcium absorbed in the gut.Thereare always some losses in the feces, urine, and in sweat.inally, 1Î±,25-dihydroxy-Vitamin D stimulates calcium absorption in thegut, and has effects in bone and kidney as well.The key to calcium homeostasis is the amount of calcium absorbed in the gut. Thereare always some losses in the feces, urine, and in sweat.