Grahame Hardie, David Carling and Alastair T.R. Sim. The A MP-activated protein kinase is a component of a protein-kinase cascade that. is activated by lipid metabolites, and which has recently been found to regulate. several key enzymes of lipid metabolism.
Arthritis is a general term for conditions that affect the joints and surrounding tissues. Joints are places in the body where bones come together, such as the knees, wrists, fingers, toes, and hips. Two common types of arthritis are osteoarthritis and rheumatoid arthritis.
This ridge may restrict movement of the joint. Osteoarthritis is less crippling than rheumatoid arthritis, in which two bone surfaces may fuse, completely immobilizing the joint. Treatment is aimed at preventing crippling deformities, relieving pain, and maintaining motion of the joint; see also treatment of arthritis.