According to The Hollywood Reporter, the four voice actors who make up the Family Guy cast -- Alex Borstein, Mila Kunis, Seth Green and Mike Henry -- has collectively negotiated a new salary between $175,000 and $225,000 per episode.
Hence, a patient with first degree heart block will typically have a soft first heart sound. For the same reasons a patient with variable PR interval (Mobitz I second degree AV block or third degree heart block) can have changing intensity of the first heart sound. Lyme carditis, anatomically corrected transposition and maternal lupus can all cause complete heart block.
Heart sound created by the closure of the AV valves to the ventricular walls. Heart sound created by the closure of the semilunar valves at the beginning of ventricular relaxation. Exit valve that only sees oxygenated blood. Valve that prevents the backflow of blood into the left ventricle. Semilunar valve through which blood leaves the left ventricle.