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Skin, mouth, genital symptoms â One characteristic feature of acute HIV infection is open sores or ulcers. These sores or ulcers can develop in the mouth, the esophagus (the tube that extends from the mouth to the stomach), the anus, or the penis. The ulcers are usually painful.
As mouth cancer can strike in a number of places, including the lips, tongue, gums and cheek, and given that early detection is so crucial for survival, itâs extremely important that we all know what to look out for. Three signs and symptoms NOT to ignore are: 1  Ulcers which do not heal in three weeks. 2  Red and white patches in the mouth. 3  Unusual lumps or swellings in the mouth or head and neck area.