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Polar molecules are hydrophylic. Because the inner portion of the phospholipid bilayer (plasma membrane) consists of hydrophobic interactions, generally polar molecules cannotâ¦ pass directly though. These molecules require protein channels to actively or passively move between the cytosol and the plasma membrane.
The plasma membrane (cell membrane) is made of two layers of phospholipids. The plasma membrane has many proteins embedded in it. The plasma membrane regulates the entry and exit of the cell. Many molecules cross the cell membrane by diffusion and osmosis. The fundamental structure of the membrane is phospho lipid bilayer and it forms a stable barrier between two aqueous compartments.