When we first meet Dory, she's just swimming around minding her own business when suddenly she bumps into Marlin and instantly offers to help him hunt down his son.
Chronic obstructive pulmonary disease (COPD) is a leading cause of death and disability internationally. Alveolar hypoxia and consequent hypoxemia increase in prevalence as disease severity increases.
Brain hypoxia and ischemia due to systemic hypoxemia, reduced cerebral blood flow (CBF), or both are the primary physiological processes that lead to hypoxic-ischemic encephalopathy. The initial compensatory adjustment to an asphyxial event is an increase in CBF due to hypoxia and hypercapnia.