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However, sadness, depression, grief, or anxiety are a common cause of weight loss that is not explained by other factors, especially among the elderly. Cancer may also cause decreased appetite. You may lose weight without trying. Cancers that may cause you to lose your appetite include: 1  Colon cancer. 2  Ovarian cancer. 3  Stomach cancer. 4  Pancreatic cancer.
Some chemotherapy drugs can make you feel sick or you may lose your appetite. If you are able to drink, then small amounts of alcohol may help to boost your appetite. But excessive drinking would not be a good idea, whatever type of chemotherapy you are on. Some chemotherapy drugs cause a change in taste.