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Latanoprost was the first prostaglandin to be approved as first-line treatment for elevated eye pressure. Three newer prostaglandins are travoprost (Travatan), bimatoprost (Lumigan),and tafluprost (Zioptan). These drugs are used to reduce eye pressure in patients with open-angle glaucoma and high ocular pressure. Side effects include itching, redness, and burning during administration. Muscle and joint pain may also occur.
NSAIDs like aspirin, ibuprofen, naproxen, and others all have the capacity to increase blood pressure. The average increase is small, but the actual amount of increase can vary widely from individual to individual. This effect occurs at doses that are typically used for pain relief and reduction of inflammation. Moreover, these drugs can reduce the effect of many types of drugs used to treat elevated blood pressure.