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However, sadness, depression, grief, or anxiety are a common cause of weight loss that is not explained by other factors, especially among the elderly. Cancer may also cause decreased appetite. You may lose weight without trying. Cancers that may cause you to lose your appetite include: 1  Colon cancer. 2  Ovarian cancer. 3  Stomach cancer. 4  Pancreatic cancer.
A. There are many things that can increase appetite -- some beneficial and some not. For example, an increase in physical activity may give you a more robust appetite which is fine if you feed your body well. But a lack of sleep or change in eating patterns, can also increase appetite, which is not so good.