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Short-Term Effects of Heroin. Often injected, the immediate effects of heroin are to modulate pain perception. As a street drug, dosing is impossible to fully control, and the side effects of decreased heart rate and breathing pose immense risk to users.
Painkiller abuse has serious short and long term effects. Though painkiller abuse can bring a temporary good feeling, it can also have negative consequences such as addiction, brain damage, or death.n addition to their short-term effects, pain meds can have serious long-term consequences for those who abuse them: 1  Tolerance for painkillers, meaning a normal, safe dose no longer controls pain. 2  A greater risk for abusing or becoming addicted to other drugs, especially in young people.