Grahame Hardie, David Carling and Alastair T.R. Sim. The A MP-activated protein kinase is a component of a protein-kinase cascade that. is activated by lipid metabolites, and which has recently been found to regulate. several key enzymes of lipid metabolism.
That said, the key difference between rheumatoid arthritis and osteoarthritis is the cause behind how the joints are affected. Osteoarthritis is a slow and progressive degenerative joint disease, that is, it will slowly develop over years of wear-and-tear on the joints and cartilage.
There are more than one hundred different types of arthritis. Two of the most common types are osteoarthritis, caused by the wear and tear exerted on the joints through a lifetime and rheumatoid arthritis, caused by an autoimmune response in the body. Osteoarthritis is the arthritis associated with getting older.