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Itâs not entirely clear why the length of acquired protection varies with different vaccines. A single dose of some vaccines provides lifelong immunity, while others require an additional dose (boosters) in order to maintain immunity.tâs not entirely clear why the length of acquired protection varies with different vaccines. A single dose of some vaccines provides lifelong immunity, while others require an additional dose (boosters) in order to maintain immunity.
Oct. 13, 2005 -- The hepatitis B vaccine lasts for more than 10 years, so a booster vaccine may not be necessary, Italian researchers report. Booster doses of vaccine do not seem necessary to ensure long-term protection, write Alessandro Zanetti, PhD, and colleagues in The Lancet. The CDC recommends the hepatitis B vaccine for these groups: All babies ; All children aged 0-18 who haven't already been vaccinated ; People whose behavior or job puts them at high risk for hepatitis B infection