having or showing a disposition to avoid exertion; slothful: an indolent person. 2. Pathology. causing little or no pain; inactive or relatively benign: an indolent ulcer that is not painful and is slow to heal.
A polynucleotide is a nucleic acid molecule consisting of a long chain of nucleotides. Nucleotides in a polynucleotide molecule are held together by a bond between the phosphate group of one nucleotide and the sugar of a second nucleotide, which is called a phosphodiester bond.
1 An enzyme called helicase unwinds the double-stranded DNA. 2  Several small proteins called single strand binding proteins (SSB) temporarily bind to each side and keep them separated. 3  An enzyme complex called DNA polymerase walks down the DNA strands and adds new nucleotides to each strand.