According to The Hollywood Reporter, the four voice actors who make up the Family Guy cast -- Alex Borstein, Mila Kunis, Seth Green and Mike Henry -- has collectively negotiated a new salary between $175,000 and $225,000 per episode.
Hence, a patient with first degree heart block will typically have a soft first heart sound. For the same reasons a patient with variable PR interval (Mobitz I second degree AV block or third degree heart block) can have changing intensity of the first heart sound. Lyme carditis, anatomically corrected transposition and maternal lupus can all cause complete heart block.
Extreme cases of heart blockage which go unnoticed and without proper medical care can even cause heart failure or congestive heart failure. This is one of the serious symptoms of heart blockage. The heart continues to beat in this condition, but is too weak to pump sufficient oxygen rich blood.