In patients with connective tissue disease, it is common for collagen and elastin to become injured by inflammation. Many connective tissue diseases feature abnormal immune system activity with inflammation in tissues as a result of an immune system that is directed against one's own body tissues (autoimmunity).Diseases in which inflammation or weakness of collagen tends to occur are also referred to as collagen diseases. connective tissue disease is any disease that has the connective tissues of the body as a target of pathology.
Big insurer Centene has announced plans to enter the Obamacare markets of Kansas, Missouri and Nevada in 2018, and also intends to expand its existing individual health plan business in six other states: Florida, Georgia, Indiana, Ohio, Texas and Washington. Centene's announcement, which boasted of another year of ... successful operations on Obamacare markets by the company, bucks a trend of stories about insurers saying they will exit Obamacare markets, including several states that Centene is committing to.
For other uses, see Missouri (disambiguation). Missouri (see pronunciations) is a state in the Midwestern region of the United States, achieving statehood in 1821. With over six million residents, it is the eighteenth most populous state and host to the mean center of United States population. The largest urban areas are St. Louis, Kansas City, Springfield, and Columbia. The capitol is in Jefferson City on the Missouri River.