Grahame Hardie, David Carling and Alastair T.R. Sim. The A MP-activated protein kinase is a component of a protein-kinase cascade that. is activated by lipid metabolites, and which has recently been found to regulate. several key enzymes of lipid metabolism.
That said, the key difference between rheumatoid arthritis and osteoarthritis is the cause behind how the joints are affected. Osteoarthritis is a slow and progressive degenerative joint disease, that is, it will slowly develop over years of wear-and-tear on the joints and cartilage.
1 Arthritis (arth = joint; itis = inflammation) is a disease of the joints and surrounding tissue. 2  Osteoarthritis and rheumatoid arthritis are the most common forms of arthritis.3  A joint is the location at which two or more bones make contact and allows for movement of the bones. Osteoporosis is a bone disease in which the amount and quality of the bone is reduced, leading to fractures (broken bones). 2  Osteoporosis produces no pain or other symptoms unless a fracture has occurred. 3  Arthritis (arth = joint; itis = inflammation) is a disease of the joints and surrounding tissue.