SNAREs are integral membrane proteins (v-SNAREs on vesicles, t-SNAREs on the target organelles) and are thought to provide specificity to the fusion process1â5. It has been suggested that Sec17p and SeclSp bind to v-SNARE/t-SNARE complexes and mediate the membrane fusion event1â3.
In 2015, 4,976 people died in motorcycle crashes, up 8.3 percent from 4,594 in 2014, according to the National Highway Traffic Safety Administration (NHTSA). In 2014, motorcyclists were 27 times more likely than passenger car occupants to die in a crash per vehicle mile traveled, and almost five times more likely to be injured.
There were 1,020 fewer pas-. senger vehicle occupant fatalities (-4.6%) in 2011 than. in 2010, with very similar decreases among passenger. cars (-4.1%) and light trucks (-5.2%). Large-truck occu-. pant fatalities increased for a second year after a large. drop in fatalities from 2008 to 2009. In 2011, there was. a 20-percent increase in large-truck occupant fatali-. ties and a 15-percent increase in large-truck occupants. injured from 2010. Motorcyclist fatalities increased in.