SNAREs are integral membrane proteins (v-SNAREs on vesicles, t-SNAREs on the target organelles) and are thought to provide specificity to the fusion process1â5. It has been suggested that Sec17p and SeclSp bind to v-SNARE/t-SNARE complexes and mediate the membrane fusion event1â3.
In 2015, 4,976 people died in motorcycle crashes, up 8.3 percent from 4,594 in 2014, according to the National Highway Traffic Safety Administration (NHTSA). In 2014, motorcyclists were 27 times more likely than passenger car occupants to die in a crash per vehicle mile traveled, and almost five times more likely to be injured.
Motor vehicle traffic accidents as a cause of death among adults aged 65 years or older decreased, as they have for younger people, from a rate of 20.6 deaths per 100,000 in 2000 to 14.3 per 100,000 in 2013. Age-adjusted death rates for unintentional poisonings and falls have increased, however.