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The more muscle a person has, the more creatinine they produce. Levels of creatinine in the blood reflect both the amount of muscle a person has and their amount of kidney function. Most men with normal kidney function have approximately 0.6 to 1.2 milligrams/deciliters (mg/dL) of creatinine. Most women with normal kidney function have between 0.5 to 1.1 mg/dL of creatinine. Women usually have lower creatinine levels than men because women, on average, have less muscle than men. Other factors that may affect the level of creatinine in the blood include body size, activity level and medications.
The normal range of creatinine in blood is: 1  0.6 to 1.2 mg/dL (or 53 to 106 mcmol/L) for males, and. 2  0.5 to 1.1 mg/dL (or 44 to 97 mcmol/L) for females.