Grahame Hardie, David Carling and Alastair T.R. Sim. The A MP-activated protein kinase is a component of a protein-kinase cascade that. is activated by lipid metabolites, and which has recently been found to regulate. several key enzymes of lipid metabolism.
That said, the key difference between rheumatoid arthritis and osteoarthritis is the cause behind how the joints are affected. Osteoarthritis is a slow and progressive degenerative joint disease, that is, it will slowly develop over years of wear-and-tear on the joints and cartilage.
About Arthritis. Arthritis is the inflammation of one or more joints. Symptoms include pain, swelling and stiffness. Types of arthritis range from those that occur commonly with age to conditions influenced by heredity.out is a type of arthritis caused by uric acid levels that comes on suddenly and severely, causing pain, redness and tenderness, often in the joint of the big toe. Osteoarthritis is a degenerative joint disease that occurs when cartilage breaks down.