Much scholarly and judicial attention has been dedicated to deciphering the Privileges or Immunities Clause of the Fourteenth Amendment, which states: âNo State shall make or enforce any law which shall abridge the privileges or immunities of citizens of the United States.â.
In the process of intramembranous ossification the formation of bone within CT, WHAT cells first aggregate in the vicinity of blood vessels and differentiate into osteoblast cells, which begin to synthesize and secrete the components of the matrix.
This matrix is produced and secreted by osteoblasts. Osteoblasts make bone in response to growth factors and mechanical stress on the bone. Counteracting the osteoblast activity are osteoclasts - the bone reabsorbing cells. Osteoclasts make and secrete digestive enzymes that break up or dissolve the bone tissue. Osteoclasts then take up or 'absorb' the bone debris and further break it down inside the cell.