Grahame Hardie, David Carling and Alastair T.R. Sim. The A MP-activated protein kinase is a component of a protein-kinase cascade that. is activated by lipid metabolites, and which has recently been found to regulate. several key enzymes of lipid metabolism.
Arthritis is a general term for conditions that affect the joints and surrounding tissues. Joints are places in the body where bones come together, such as the knees, wrists, fingers, toes, and hips. Two common types of arthritis are osteoarthritis and rheumatoid arthritis.
Osteoarthritis is the most common form of arthritis to affect the knees and usually occurs in the middle-aged and the elderly. Once osteoarthritis develops, the joint cartilage will gradually wear away whereas with rheumatoid arthritis, the joint cartilage wears away more quickly and can occur at any age.