Grahame Hardie, David Carling and Alastair T.R. Sim. The A MP-activated protein kinase is a component of a protein-kinase cascade that. is activated by lipid metabolites, and which has recently been found to regulate. several key enzymes of lipid metabolism.
That said, the key difference between rheumatoid arthritis and osteoarthritis is the cause behind how the joints are affected. Osteoarthritis is a slow and progressive degenerative joint disease, that is, it will slowly develop over years of wear-and-tear on the joints and cartilage.
How Rheumatoid Arthritis Differs From Osteoarthritis. Most people with arthritis have osteoarthritis, which commonly occurs with age. Thereâs another type called rheumatoid arthritis (RA), a serious autoimmune disease. The two are often confusedwhich can be endlessly frustrating for those with RA.