Grahame Hardie, David Carling and Alastair T.R. Sim. The A MP-activated protein kinase is a component of a protein-kinase cascade that. is activated by lipid metabolites, and which has recently been found to regulate. several key enzymes of lipid metabolism.
Arthritis is a general term for conditions that affect the joints and surrounding tissues. Joints are places in the body where bones come together, such as the knees, wrists, fingers, toes, and hips. Two common types of arthritis are osteoarthritis and rheumatoid arthritis.
Osteoarthritis is the result of wear and tear on your joints, which causes weakening and deterioration of your cartilage [ Mayo Clinic ]. Rheumatoid arthritis, on the other hand, is an auto-immune disorder, whereby your body attacks and destroys joint cartilage [ NIAMS ].Both conditions, however, share common symptoms, including joint paint, stiffness and swelling. The risk factors for osteoarthritis and rheumatoid arthritis are fairly different.heumatoid arthritis also causes other symptoms that are unrelated to joint deterioration, such as fatigue, fever and a vague feeling of sickness. The symptoms of osteoarthritis get progressively worse as you age [ Mayo Clinic ]. The symptoms of rheumatoid arthritis, however, can flare up and dissipate.