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What is PUVA? PUVA or photochemotherapy is a type of ultraviolet radiation treatment (phototherapy) used for severe skin diseases. PUVA is a combination treatment which consists of Psoralens (P) and then exposing the skin to UVA (long wave ultraviolet radiation). It has been available in its present form since 1976.
PUVA is a combination of UVA light and a chemical called psoralen (P). UVA is not beneficial in treating psoriasis on its own; instead it must be combined with psoralen (a chemical derived from plants) which makes the skin more sensitive to the UVA light.