Historically part of Midlothian, the city has long been a centre of education, particularly in the fields of medicine, Scots law, literature, the sciences and engineering. The University of Edinburgh, founded in 1582 and now one of four in the city, was placed 17th in the QS World University Rankings in 2013 and 2014. The city is also famous for the Edinburgh International Festival and the Fringe, the latter being the world's largest annual international arts festival.
Onset and Duration. It takes approximately 15 to 45 minutes for caffeine to reach its peak levels in your bloodstream. Caffeine has a half-life of approximately five to six hours, meaning that it takes this long for its concentration in your bloodstream to reduce by half.
Answers. Best Answer: Effects of Caffeine on the Nervous System Caffeine is a central nervous system stimulant. In moderate doses, caffeine can: increase alertness reduce fine motor coordination cause insomnia cause headaches, nervousness and dizziness In massive doses, caffeine is lethal.n moderate doses, caffeine can: increase alertness reduce fine motor coordination cause insomnia cause headaches, nervousness and dizziness In massive doses, caffeine is lethal.