Grahame Hardie, David Carling and Alastair T.R. Sim. The A MP-activated protein kinase is a component of a protein-kinase cascade that. is activated by lipid metabolites, and which has recently been found to regulate. several key enzymes of lipid metabolism.
That said, the key difference between rheumatoid arthritis and osteoarthritis is the cause behind how the joints are affected. Osteoarthritis is a slow and progressive degenerative joint disease, that is, it will slowly develop over years of wear-and-tear on the joints and cartilage.
1 rheumatoid arthritis occurs due to an autoimmune response of the body while osteoarthritis is mainly a result of mechanical wear and tear of the cartilage in between the joints 2 osteoarthritis affects older people but rheumatoid arthritis can affect anyone3oth rheumatoid arthritis and osteoarthritis are painful conditions affecting the joints of the human body however there are a number of differences between the two conditions