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However, sadness, depression, grief, or anxiety are a common cause of weight loss that is not explained by other factors, especially among the elderly. Cancer may also cause decreased appetite. You may lose weight without trying. Cancers that may cause you to lose your appetite include: 1  Colon cancer. 2  Ovarian cancer. 3  Stomach cancer. 4  Pancreatic cancer.
A decreased desire to eat is a symptom that is common to numerous medical and psychological conditions. Almost any illness can lead to a decrease in appetite. When severe, decreased appetite can lead to unwanted weight loss and malnutrition. Medically, a decrease in appetite is referred to as anorexia.