having or showing a disposition to avoid exertion; slothful: an indolent person. 2. Pathology. causing little or no pain; inactive or relatively benign: an indolent ulcer that is not painful and is slow to heal.
A polynucleotide is a nucleic acid molecule consisting of a long chain of nucleotides. Nucleotides in a polynucleotide molecule are held together by a bond between the phosphate group of one nucleotide and the sugar of a second nucleotide, which is called a phosphodiester bond.
The process of breaking the hydrogen bonds between the nucleotide base pairs in double-stranded DNA requires energy. To break the bonds, helicases use the energy stored in a molecule called ATP, which serves as the energy currency of cells.he process of breaking the hydrogen bonds between the nucleotide base pairs in double-stranded DNA requires energy. To break the bonds, helicases use the energy stored in a molecule called ATP, which serves as the energy currency of cells.