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Drug-induced hypothyroidism may be caused by: 1  Drugs used for hyperthyroidism (overactive thyroid), such as propylthiouracil (PTU), radioactive iodine, potassium iodide, and methimazole. 2  Treatment with lithium or iodides in certain people.
4. Hypothyroidism is treated by supplements of thyroid hormones and hyperthyroidism is treated by anti-thyroid drugs. 5. Hypothyroidism shows decreased levels of T3 and T4 and increased levels of TSH whereas in hyperthyroidism, there is an increased levels of T3 and T4 and a decreased level in TSH.n hyperthyroidism, there are increased levels of thyroid hormones T3 and T4 and decrease in the levels of TSH. TSH is thyroid stimulating hormone. SUMMARY: 1. Hyperthyroidism is increased levels of thyroid hormones whereas hypothyroidism is decreased levels of thyroid hormones.