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Secondary syphilis symptoms may include: 1  Skin rash, usually on the palms of the hands and soles of the feet. 2  Sores called mucous patches in or around the mouth, vagina, or penis.  Moist, warty patches (called condylomata lata) in the genitals or skin folds.
Secondary syphilis â In this stage, syphilis bacteria spread throughout the body. This usually causes a rash over most of the body along with fever, aches and pains, and other symptoms. This stage begins six to eight weeks after a person is exposed to syphilis, and it lasts up to one year. Latent syphilis â This stage begins when the secondary stage ends.