Several reports demonstrate unexplained consequences of mutations on the expression of the different dystrophin isoforms and their balance. The most prominent example is found in some cases of X-linked dilated cardiomyopathy (XLDC).
In particular, calcitonin has the ability to decrease blood calcium levels at least in part by effects on two well-studied target organs: 1  Bone: Calcitonin suppresses resorption of bone by inhibiting the activity of osteoclasts, a cell type that digests bone matrix, releasing calcium and phosphorus into blood.
Absorbing calcium into the bones certainly is not the purpose of calcitonine, for it stimulates excretion of calcium too. Due to the action of calcitonine, the increased blood-calcium level decreases, inhibiting calcitonine release and stimulating secretion of two other calcium-hormones; PTH and calcitriol.