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Lexapro has a half-life of 27-32 hours and I think is totally out of your system in about 6 days.
Responses (21) Hi,Sam!! Lexapro DOES have a long half life of about 30hrs which means after taking a 10mg dose only 5 mg would remain in your body; after 60 hrs only 2.5mg, etc. But because it has such a long half life it also takes a very long time to reach steady state therapeutic levels that might cause a withdrawal syndrome when stopped.