A Brief Explanation of an Over-the-Counter Market | Definition. A over-the-counter market (OTC) refers to a decentralized and informal way of exchanging stocks, derivatives, or other assets between two parties.
The leading strand is built by using the lagging strand of the old molecule as the template. Replication of the leading strand begins with the enzyme âprimaseâ. Primase adds a small complementary piece of RNA (~10 nucleotides), called an âRNA primerâ, near the end of the lagging strand. The RNA primer gives an enzyme called âDNA polymerase IIIâ something to attach a DNA nucleotide to. A jury-rigged design, RNA primers are necessary because DNA polymerase III can only attach nucleotides to the 3â end of a pre-existing nucleotide.
Here the new strands of DNA are added. In order for the DNA strands to separate, 3 types of enzymes are needed. Helicases, single-strand binding proteins and topoisomerase. Priming: Once the replication fork is established a short segment of RNA,formed by an enzyme called primase, initiates the process of replication.With the primer in place, DNA polymerase catalyzes the synthesis of a new strand of DNA.The new nucleotides align themselves with the old DNA. These strands grow from the 5'--3' direction. The energy for this process comes from the 2 P molecules attached to the nucleotide as it is moved into place.riming: Once the replication fork is established a short segment of RNA,formed by an enzyme called primase, initiates the process of replication. With the primer in place, DNA polymerase catalyzes the synthesis of a new strand of DNA. The new nucleotides align themselves with the old DNA.