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Polar molecules are hydrophylic. Because the inner portion of the phospholipid bilayer (plasma membrane) consists of hydrophobic interactions, generally polar molecules cannotâ¦ pass directly though. These molecules require protein channels to actively or passively move between the cytosol and the plasma membrane.
Transporting substances across the plasma membrane can require that the cell use some of its energy. If energy is used, the transport is called active. If molecules can pass through the plasma membrane without using energy, the molecules are using passive transport. Helping the molecules across: Active transport Sometimes, the molecules are just too big to easily flow across the plasma membranes or dissolve in the water so that they can be filtered through the membrane.