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Dependency, or addiction, is the most common of long-term heroin effects. Heroin is often considered the most addictive of all legal and illegal substances that are commonly abused for their mind-altering effects.
When heroin is directly injected into the blood stream, the effect of the high happens quickly after injection. You will feel in almost immediate rush and flush of the skin. This rush take about 6-8 seconds to happen.The peak effects of heroin can be felt about 10 minutes after injection.In contrast, intramuscular injection of heroin produces a relatively slow onset of euphoria (5 to 8 minutes). When heroin is sniffed or smoked, peak effects are usually felt within 10 to 15 minutes.eroin effects the opioid receptors in the brain which disrupts endorphin production sent out to the rest of the body. This action is directly responsible for creating intense euphoria while suppressing physical pain and the reason why heroin also acts as an analgesic (pain killer) on the body system.