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Causes of Heart Disease. Heart disease occurs when the arteries and blood vessels that lead to the heart are blocked or not carrying blood correctly. When this happens, important nutrients, such as oxygen, cannot reach your heart.ou may not show symptoms of the disease at certain times. Heart disease is sometimes called âcoronary heart diseaseâ or âCHD.â It is the leading cause of death among adults in the United States, according to the National Heart, Lung, and Blood Institute (NHLBI).
There are many different forms of heart disease. The most common cause of heart disease is narrowing or blockage of the coronary arteries, the blood vessels that supply blood to the heart itself. This is called coronary artery disease and happens slowly over time. It's the major reason people have heart attacks.