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Skin, mouth, genital symptoms â One characteristic feature of acute HIV infection is open sores or ulcers. These sores or ulcers can develop in the mouth, the esophagus (the tube that extends from the mouth to the stomach), the anus, or the penis. The ulcers are usually painful.
Advanced Symptoms of HIV/AIDS. As HIV progresses, there may be bouts of diarrhea, nausea, vomiting, and weight loss. Other symptoms include severe headache, joint pain, and muscle aches. Shortness of breath, chronic cough, and difficulty swallowing are not uncommon. In the later stages, HIV can lead to short-term memory loss, mental confusion, and coma. The most advanced stage of HIV is called acquired immune deficiency syndrome (AIDS). At this stage, the immune system is severely compromised and infections become increasingly difficult to fight off.