Grahame Hardie, David Carling and Alastair T.R. Sim. The A MP-activated protein kinase is a component of a protein-kinase cascade that. is activated by lipid metabolites, and which has recently been found to regulate. several key enzymes of lipid metabolism.
Arthritis is a general term for conditions that affect the joints and surrounding tissues. Joints are places in the body where bones come together, such as the knees, wrists, fingers, toes, and hips. Two common types of arthritis are osteoarthritis and rheumatoid arthritis.
The most common type of arthritis, osteoarthritis involves wear-and-tear damage to the cartilage that caps the bones in your joints. Rheumatoid arthritis occurs when your immune system mistakenly attacks the lining of your joints, causing a painful swelling that can eventually result in joint deformity.While both rheumatoid arthritis and osteoarthritis can affect the small joints of the hand, there are differences.Rheumatoid arthritis tends to affect the middle joints of the fingers and the joints where the fingers attach to the hand.Osteoarthritis more commonly affects the joints at the ends of the fingers and at the base of the thumb. In rheumatoid arthritis, the same joints usually are affected on both sides of the body.heumatoid arthritis tends to affect the middle joints of the fingers and the joints where the fingers attach to the hand. Osteoarthritis more commonly affects the joints at the ends of the fingers and at the base of the thumb. In rheumatoid arthritis, the same joints usually are affected on both sides of the body.