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Causes of urinary tract infections. The vast majority of UTI cases are caused by the bacterium Escherichia coli (E. coli), usually found in the digestive system. Chlamydia and Mycoplasma bacteria can infect the urethra but not the bladder.
Most often, urinary tract infections (UTIs) are caused by bacteria. A UTI can occur anywhere in your urinary tract. This includes your kidneys, bladder, or urethra (the tube that carries urine from your bladder out of your body). The bacteria that cause a UTI can come from your skin or your rectum.