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Definition of caustic. 1 : capable of destroying or eating away by chemical action : corrosive The chemical was so caustic that it ate through the pipe. 2 : marked by incisive sarcasm a caustic film review caustic humor.
Noun. 1. caustic-any chemical substance that burns or destroys living tissue. chemical compound, compound - (chemistry) a substance formed by chemical union of two or more elements or ingredients in definite proportion by weight. lye-a strong solution of sodium or potassium hydroxide.