Multiple myeloma is staged by estimating the myeloma tumor cell mass on the basis of the amount of monoclonal (or myeloma) protein (M protein) in the serum and/or urine, along with various clinical parameters, such as hemoglobin and serum calcium concentrations, the number of lytic bone lesions, and the presence or absence of renal failure.
At present, daylight saving time in the United States. 1  begins at 2:00 a.m. on the second Sunday of March and. 2  ends at 2:00 a.m. on the first Sunday of November.
At 2 a.m. on March 8, 2015, Americans will turn their clocks ahead one hour, marking the beginning of Daylight Saving Time (DST) . The federal law that established daylight time in the United States does not require any area to observe daylight saving time.