It also regulates the amount of water released from the body into the atmosphere through transepidermal water loss (TEWL). In humans, it is thinnest on the eyelids at 0.05 mm (0.0020 in) and thickest on the palms and soles at 1.5 mm (0.059 in).
When opiates are prescribed by a physician for the treatment of pain and are taken in the prescribed dosage, they are safe and there is little chance of opiate addiction. However, when opiates are abused and taken in excessive doses, opiate addiction can result, leading to a need for rapid detoxification.wo important effects produced by opiates, such as morphine, are pleasure (or reward) and pain relief. The brain itself also produces substances known as endorphins that activate the opiate receptors.
Home Â» Prescription Painkillers. Prescription painkillers, or opiates, are analgesic medications available only by prescription from a doctor, dentist, veterinarian or other licensed medical personnel.Natural opiates are contained in the resin of the opium poppy plant and include morphine and codeine.buse, Tolerance, Addiction and Withdrawal. Prescription painkillers can cause sedation and euphoria and are commonly abused. Chronic use can lead to tolerance, characterized by a patientâs need to consume more and more of the drug to achieve the same pain relief.