DNA polymerases need a primer oligonucleotide (RNA or DNA) - their substrates are an existing 3'-OH group and a dNTP. The primase however is a typical RNA polymerase, capable of initiating polynucleotide synthesis de novo by positioning a complementary ribonucleoside 5'-triphosphate opposite its complementary DNA base.
Alison Schapker. Alison Schapker is an American television writer and producer. She is well known for her work on the ABC espionage series Alias and for the FOX science-fiction series Fringe.
Dinner for Schmucks. Dinner for Schmucks is a 2010 American comedy film directed by Jay Roach. The film is the American adaptation of the 1998 French comedy Le DÃ®ner de Cons and was written by David Guion and Michael Handelman. It stars Steve Carell and Paul Rudd, who had previously teamed up in Anchorman: The Legend of Ron Burgundy and The 40-Year-Old Virgin.