DNA polymerases need a primer oligonucleotide (RNA or DNA) - their substrates are an existing 3'-OH group and a dNTP. The primase however is a typical RNA polymerase, capable of initiating polynucleotide synthesis de novo by positioning a complementary ribonucleoside 5'-triphosphate opposite its complementary DNA base.
Alison Schapker. Alison Schapker is an American television writer and producer. She is well known for her work on the ABC espionage series Alias and for the FOX science-fiction series Fringe.
JEFFREY PFEFFER is the Thomas D. Dee II Professor of Organizational Behavior at the Graduate School of Business, Stanford University where he has taught since 1979. He is the author or co-author of 14 books including: The Human Equation: Building Profits by Putting People First;