In the initial âexpandingâ phase, lymphatic fluid flows at an increased rate and volume from an affected joint to the draining LN via afferent lymphatic vessels. The LN volume expands, presumably to accommodate the influx of cells and lymph exiting the inflamed synovium.
Other signs and symptoms of COPD may include: 1  Shortness of breath, especially during physical activities. 2  Wheezing. 3  Chest tightness.  Having to clear your throat first thing in the morning, due to excess mucus in your 1  lungs. A chronic cough that may produce mucus (sputum) that may be clear, white, yellow or greenish.
4. Fatigue 4. Fatigue Fatigue, or tiredness, is another common symptom in people with COPD. You may find that you get tired more easily than you did in the past. A loss of energy or stamina may also occur. If you feel more tired than usual, talk to your doctor to determine if itâs a result of COPD.