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The term ' Activated Partial Thromboplastin Time ( APTT ) ' derives from the original form of the test ( devised in 1953 ) in which only the phospholipid concentration of the test was controlled ( as opposed to the phospholipid and the surface activator concentrations ) and the name ' partial thromboplastin ' was applied at the time to phospholipid ...
Reference values for aPTT vary among laboratories, but generally range between 25 and 38 seconds. The aPTT of a newborn will usually be prolonged and may be up to 55 seconds at birth.It decreases to the adult range by 6 months of age. (Note: each lab has its own reference values based upon the equipment and reagents used.). The aPTT is the most commonly used test to monitor heparin therapy.The therapeutic goal for a patient being anticoagulated with heparin, is an aPTT approximately 1.5 to 2.5 times the mean normal value.Note: each lab has its own reference values based upon the equipment and reagents used.). The aPTT is the most commonly used test to monitor heparin therapy. The therapeutic goal for a patient being anticoagulated with heparin, is an aPTT approximately 1.5 to 2.5 times the mean normal value.