1 The LLC must pay a fee if the California total income is equal to or greater than $250,000. 2  The LLC must estimate the fee it will owe for the year and make an estimated fee payment. 3  See Estimated Payments below.
Ligand Definition. A ligand is an atom, ion, or molecule that donates or shares one or more of its electrons through a covalent bond with a central atom or ion. It is a complexing group in coordination chemistry that stabilizes the central atom and determines it reactivity.
The binding typically results in a change of conformation of the target protein. In DNA-ligand binding studies, the ligand can be a small molecule, ion, or protein which binds to the DNA double helix. The relationship between ligand and binding partner is a function of charge, hydrophobicity, and molecular structure. The instance of binding occurs over an infinitesimal range of time and space, so the rate constant is usually a very small number.