The safe amount of any narcotic depends on a personâs individual tolerance to opioid medications. Tramadol is always started at a smaller initial dose of 100 mg per day. In patients whoâve experienced more exposure to the drug, safe doses may be as high as 450 mg a day.
whether a substance is a gas, liquid, or solid depends on the balance between the kinetic energy of its particles and the strength of the interactions between the particles gas
Key Points. 1  All particles have energy, and the energy varies depending on the temperature the sample of matter is in, which determines if the substance is a solid, liquid, or gas. 2  The temperature of a substance is a measure of the average kinetic energy of the particles.  There are spaces between particles of matter.