Multiple myeloma is staged by estimating the myeloma tumor cell mass on the basis of the amount of monoclonal (or myeloma) protein (M protein) in the serum and/or urine, along with various clinical parameters, such as hemoglobin and serum calcium concentrations, the number of lytic bone lesions, and the presence or absence of renal failure.
At present, daylight saving time in the United States. 1  begins at 2:00 a.m. on the second Sunday of March and. 2  ends at 2:00 a.m. on the first Sunday of November.
The Federal law was amended in 1986 to begin Daylight Saving Time on the first Sunday in April. Under legislation enacted in 1986, Daylight Saving Time in the U.S. began at 2:00 a.m. on the first Sunday of April and ended at 2:00 a.m. on the last Sunday of October. An Act to preserve daylight and provide standard time for the United States ' was enacted on March 19, 1918. [See law] It both established standard time zones and set summer DST to begin on March 31, 1918. Daylight Saving Time was observed for seven months in 1918 and 1919.