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Causes of urinary tract infections. The vast majority of UTI cases are caused by the bacterium Escherichia coli (E. coli), usually found in the digestive system. Chlamydia and Mycoplasma bacteria can infect the urethra but not the bladder.
1 Urinary tract infections (UTIs) are infections of the urethra, bladder, ureters, or the kidneys, which comprise the urinary tract.  E. coli bacteria cause the majority of UTIs, but many other bacteria, fungi, and parasites may also cause UTIs.