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White matter is located at the base of the brain between the cerebellum and the brainstem. It is made of long nerve fibers called axons. The axons are insulated by myelin, sheaths of fat that give the region the white color for which it is named. The myelin helps speed up the transmission of signals along the axons.
The white matter of the brain is located in the central and subcortical regions of the cerebral and cerebellar hemispheres and accounts for about 60 % of the total brain volume. The white matter includes the major commissural tracts, the cortical association fibers, and all the cortical afferent and efferent fibers.