In the initial âexpandingâ phase, lymphatic fluid flows at an increased rate and volume from an affected joint to the draining LN via afferent lymphatic vessels. The LN volume expands, presumably to accommodate the influx of cells and lymph exiting the inflamed synovium.
Other signs and symptoms of COPD may include: 1  Shortness of breath, especially during physical activities. 2  Wheezing. 3  Chest tightness.  Having to clear your throat first thing in the morning, due to excess mucus in your 1  lungs. A chronic cough that may produce mucus (sputum) that may be clear, white, yellow or greenish.
People living with chronic obstructive pulmonary disease (COPD) may have different kinds of symptoms. Some symptoms are early signs of COPD. As the disease progresses, people with COPD may start to have more symptoms. Symptoms may slowly get worse, and start to happen more often. Some symptoms can be signs that a person is having an exacerbation â a COPD attack. Other kinds of symptoms are âsevereâ, because they are signs of very serious problems that need treatment right away.