Origin of GLIRIDAE. New Latin, from Glir-, Glis, type genus + -idae. This word doesn't usually appear in our free dictionary, but the definition from our premium Unabridged Dictionary is offered here on a limited basis.Note that some information is displayed differently in the Unabridged.rigin of GLIRIDAE. New Latin, from Glir-, Glis, type genus + -idae. This word doesn't usually appear in our free dictionary, but the definition from our premium Unabridged Dictionary is offered here on a limited basis.
knockout mouse(Noun) Any of several forms of mice that have been genetically engineered by inactivating specific genes. Knockout mouse. A knockout mouse is a genetically engineered mouse in which researchers have inactivated, or knocked out, an existing gene by replacing it or disrupting it with an artificial piece of DNA.
2. ES cells containing a knockout mutation in one allele of the gene being studied are introduced into early mouse embryos. The resultant mice will be chimeras containing tissues derived from both the transplanted ES cells and the host cells.These cells can contribute to both the germ-cell and somatic-cell populations.ene knockout is a technique for selectively inactivating a gene by replacing it with a mutant allele in an otherwise normal organism. This technique of disrupting gene function, which has been widely used in yeast and mice, is a powerful tool for unraveling the mechanisms by which basic cellular processes occur.