In the initial âexpandingâ phase, lymphatic fluid flows at an increased rate and volume from an affected joint to the draining LN via afferent lymphatic vessels. The LN volume expands, presumably to accommodate the influx of cells and lymph exiting the inflamed synovium.
COPD exacerbation. Many people with COPD have attacks called flare-ups or exacerbations (say egg-ZASS-er-BAY-shuns). This is when your usual symptoms quickly get worse and stay worse. A COPD flare-up can be dangerous, and you may have to go to the hospital. Symptoms include: Coughing up more mucus than usual. A change in the color or thickness of that mucus. More shortness of breath than usual. Greater tightness in your chest.
In the early stages of COPD, there may be no symptoms, or you may only have mild symptoms, such as: 1  A nagging cough (often called smoker's cough). 2  Shortness of breath, especially with physical activity. 3  Wheezing (a whistling sound when you breathe).4  Tightness in the chest.hronic obstructive pulmonary disease (COPD) is a serious lung disease that gradually makes it harder and harder to breathe. COPD includes emphysema and chronic bronchitis.