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The most common cause of intrauterine growth restriction is an abnormality in the placenta. A placental abnormality can cause intrauterine growth restriction because the fetus may become malnourished.Some other potential causes include: 1  Congenital or chromosomal abnormalities. 2  Heart disease.3  Diabetes.he most common cause of intrauterine growth restriction is an abnormality in the placenta. A placental abnormality can cause intrauterine growth restriction because the fetus may become malnourished. Some other potential causes include: 1  Congenital or chromosomal abnormalities. 2  Heart disease. 3  Diabetes.
It may seem logical to conclude then, that any increase in production of lactic acid and hence lactate is detrimental as it will increase the production of hydrogen ions. However, accumulation is the key term here as an increased production of hydrogen ions (due to an increase production of lactic acid) will have no detrimental effect if clearance is just as fast.