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Ibuprofen is not safe for continuous, daily, long-term use due to its affect on the liver, kidneys and blood pressure.Watch pain management expert Devi Nampiaparampil, MD, explain how too much ibuprofen can have a negative impact over time.t can also increase the risk of bleeding in the stomach. Your doctor will need to regularly test your urine and blood if you are taking ibuprofen long-term. Over-the-counter ibuprofen should not be used for more than 10 days to treat body aches, unless directed to do so by your doctor.
Painkiller Overdose: How Much Ibuprofen Is Too Much In One Day? Dec 14, 2016 01:03 PM By Elana Glowatz @ElanaGlow Over-the-counter painkillers like ibuprofen could be dangerous in high doses. Sometimes when our heads hurt, or any other body part for that matter, a couple of ibuprofens donât seem like enough. Taking too much of the over-the-counter painkiller, however, could be dangerous. There are limits to what the body can tolerate. Both Motrin and Advil â two of the most popular nonsteroidal anti-inflammatory drugs, also known as NSAIDs â come with warning labels that suggest a maximum adult dose of 1,200 milligrams per day. With 200 milligram pills, that translates to one every four hours.