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Sclerodermaâs main types are localized and systemic. Localized means the disease affects only certain parts of the body. Systemic means it can affect the whole body. 1  The localized type often affects only skin tissues. 2  It does not harm major organs.3  It may get better or go away without help.4  But it can be severe in some people and can leave skin damage.ocalized means the disease affects only certain parts of the body. Systemic means it can affect the whole body. 1  The localized type often affects only skin tissues. 2  It does not harm major organs. 3  It may get better or go away without help. 4  But it can be severe in some people and can leave skin damage.
Find out about the different types of non melanoma skin cancer. Types of non melanoma skin cancer. Non melanoma skin cancer includes 2 main types: basal cell skin cancer (BCC) squamous cell skin cancer (SCC) They're named after the types of skin cells where the cancer develops. It's possible for a non melanoma skin cancer to be a mixture of both these types. Non melanoma skin cancer is different from melanoma. Melanoma is the type of skin cancer that most often develops from a mole.