General bacterial porin family. General bacterial porins are a family of proteins from the outer membranes of Gram-negative bacteria. The porins act as molecular filters for hydrophilic compounds. They are responsible for the 'molecular sieve' properties of the outer membrane. Porins form large water-filled channels which allow the diffusion of hydrophilic molecules into the periplasmic space. Some porins form general diffusion channels that allow any solute up to a certain size to cross the membrane, while other porins are sp
Cystic fibrosis transmembrane conductance regulator (CFTR) is a membrane protein and chloride channel in vertebrates that is encoded by the CFTR gene. CFTR is an ABC transporter-class ion channel that codes for a protein that conducts chloride and thiocyanate ions across epithelial cell membranes.
Genes are found on structures in the cells of the body called chromosomes. Each cell normally contains 46 total, or 23 pairs of chromosomes. The seventh pair of chromosomes contains a gene called the cystic fibrosis transmembrane regulator (CFTR) gene.Mutations or errors in this gene are what cause CF.This gene is quite large and complex.ore than 1,800 different mutations in this gene have been found that cause CF. According to the Cystic Fibrosis Foundation, the risk for having a mutation in the gene for CF depends on your ethnic background if you have no family history of CF: Ethnic Background. Risk of CF Mutation.