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DOSAGE AND ADMINISTRATION. The dosage of ZYLOPRIM (allopurinol) to accomplish full control of gout and to lower serum uric acid to normal or near-normal levels varies with the severity of the disease.The average is 200 to 300 mg/day for patients with mild gout and 400 to 600 mg/day for those with moderately severe tophaceous gout.OSAGE AND ADMINISTRATION. The dosage of ZYLOPRIM (allopurinol) to accomplish full control of gout and to lower serum uric acid to normal or near-normal levels varies with the severity of the disease.
Dosage for Gout To help avoid a flare-up of gout attacks (which can occur when starting allopurinol), it is recommended to start at a low dosage for treating gout: allopurinol 100 mg once daily. After that, your healthcare provider may increase your dose by 100 mg per day each week, until the maximum dose is reached (800 mg daily) or until your uric acid levels are under control (are 6 mg/dL or less). People with kidney disease should take a lower dose, depending on the severity of their kidney problems.