It also regulates the amount of water released from the body into the atmosphere through transepidermal water loss (TEWL). In humans, it is thinnest on the eyelids at 0.05 mm (0.0020 in) and thickest on the palms and soles at 1.5 mm (0.059 in).
When opiates are prescribed by a physician for the treatment of pain and are taken in the prescribed dosage, they are safe and there is little chance of opiate addiction. However, when opiates are abused and taken in excessive doses, opiate addiction can result, leading to a need for rapid detoxification.wo important effects produced by opiates, such as morphine, are pleasure (or reward) and pain relief. The brain itself also produces substances known as endorphins that activate the opiate receptors.
Opioids are potent analgesic drugs that are often prescribed to relieve acute pain, pain from serious illnesses such as cancer and chronic pain.Some are used to suppress chronic cough and diarrhea.Opioids include naturally occurring opiates derived from the opium poppy plant such as morphine and codeine, synthetic opiates such as fentanyl and semi-synthetic opiates including oxycodone and hydrocodone.Opioids are thought to block pain signals in the brain by attaching to certain opioid receptors.pioids are potent analgesic drugs that are often prescribed to relieve acute pain, pain from serious illnesses such as cancer and chronic pain. Some are used to suppress chronic cough and diarrhea.