duete; see due, ty 2 ]. syn: duty, obligation refer to something a person feels bound to do. A duty often applies to what a person performs in fulfillment of the permanent dictates of conscience, piety, right, or law: one's duty to tell the truth; a parent's duty to raise children properly.
Mutations in the RB1 gene are responsible for most cases of retinoblastoma. RB1 is a tumor suppressor gene, which means that it normally regulates cell growth and keeps cells from dividing too rapidly or in an uncontrolled way.
Retinoblastoma is an eye cancer that typically develops in children before 5 years of age. This cancer develops in the retinaâthe part of the eye that helps a person see color and light. Retinoblastoma may affect one or both eyes. In about two-thirds of all cases only one eye is affected.