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When the ventricles contract, atrioventricular valves close to prevent blood from flowing back into the atria. When the ventricles relax, semilunar valves close to prevent blood from flowing back into the ventricles.
The four heart valves make sure that blood always flows freely in a forward direction and that there is no backward leakage. Blood flows from your right and left atria into your ventricles through the open mitral and tricuspid valves. When the ventricles are full, the mitral and tricuspid valves shut. This prevents blood from flowing backward into the atria while the ventricles contract (squeeze).