General bacterial porin family. General bacterial porins are a family of proteins from the outer membranes of Gram-negative bacteria. The porins act as molecular filters for hydrophilic compounds. They are responsible for the 'molecular sieve' properties of the outer membrane. Porins form large water-filled channels which allow the diffusion of hydrophilic molecules into the periplasmic space. Some porins form general diffusion channels that allow any solute up to a certain size to cross the membrane, while other porins are sp
Cystic fibrosis transmembrane conductance regulator (CFTR) is a membrane protein and chloride channel in vertebrates that is encoded by the CFTR gene. CFTR is an ABC transporter-class ion channel that codes for a protein that conducts chloride and thiocyanate ions across epithelial cell membranes.
Noun. 1. CFTR-the gene that is mutated in cystic fibrosis. cystic fibrosis transport regulator.mutant gene-a gene that has changed so that the normal transmission and expression of a trait is affected.1  Facebook. 2  Twitter.oun. 1. CFTR-the gene that is mutated in cystic fibrosis. cystic fibrosis transport regulator.