In the initial âexpandingâ phase, lymphatic fluid flows at an increased rate and volume from an affected joint to the draining LN via afferent lymphatic vessels. The LN volume expands, presumably to accommodate the influx of cells and lymph exiting the inflamed synovium.
Other signs and symptoms of COPD may include: 1  Shortness of breath, especially during physical activities. 2  Wheezing. 3  Chest tightness.  Having to clear your throat first thing in the morning, due to excess mucus in your 1  lungs. A chronic cough that may produce mucus (sputum) that may be clear, white, yellow or greenish.
COPD symptoms often don't appear until significant lung damage has occurred, and they usually worsen over time, particularly if smoking exposure continues. For chronic bronchitis, the main symptom is a daily cough and mucus (sputum) production at least three months a year for two consecutive years. Other signs and symptoms of COPD may include: Shortness of breath, especially during physical activities. Wheezing.