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White matter is located at the base of the brain between the cerebellum and the brainstem. It is made of long nerve fibers called axons. The axons are insulated by myelin, sheaths of fat that give the region the white color for which it is named. The myelin helps speed up the transmission of signals along the axons.
Diagnosis of White Matter Damage (WMD) White matter in the brain is made of axons, which are like wires that carry messages between neurons and supporting cells. White matter sits underneath the brainâs cortex, or grey matter. In general, white matter damage (WMD) is caused by a lack of oxygen to that part of the brain. Periventricular leucomalacia (PVL) is a condition in which decreased blood flow to brain tissue causes it to soften up and eventually die.