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Sclerodermaâs main types are localized and systemic. Localized means the disease affects only certain parts of the body. Systemic means it can affect the whole body. 1  The localized type often affects only skin tissues. 2  It does not harm major organs.3  It may get better or go away without help.4  But it can be severe in some people and can leave skin damage.ocalized means the disease affects only certain parts of the body. Systemic means it can affect the whole body. 1  The localized type often affects only skin tissues. 2  It does not harm major organs. 3  It may get better or go away without help. 4  But it can be severe in some people and can leave skin damage.
Presented by Amanda Thorpe. These symptoms may occur in systemic scleroderma (systemic sclerosis) but usually not in localized scleroderma, such as linear or morphea scleroderma. See Types of Scleroderma.hecklist of Systemic Scleroderma Symptoms. Please consult your doctor if you have two or more of the symptoms listed on our (separate) Checklist page, which are sometimes due to systemic sclerosis (scleroderma).