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Sclerodermaâs main types are localized and systemic. Localized means the disease affects only certain parts of the body. Systemic means it can affect the whole body. 1  The localized type often affects only skin tissues. 2  It does not harm major organs.3  It may get better or go away without help.4  But it can be severe in some people and can leave skin damage.ocalized means the disease affects only certain parts of the body. Systemic means it can affect the whole body. 1  The localized type often affects only skin tissues. 2  It does not harm major organs. 3  It may get better or go away without help. 4  But it can be severe in some people and can leave skin damage.
Steroids can be manufactured synthetically as drugs. There are different types of steroids and they all have different effects on the body. Common types of steroids used in cancer treatment are: hydrocortisone, dexamethasone, methylprednisolone and prednisolone.teroids can also be man-made and used as part of your cancer treatment. Steroids can be taken as tablets or liquids by mouth or by injection, depending on the type your doctor prescribes.