In the initial âexpandingâ phase, lymphatic fluid flows at an increased rate and volume from an affected joint to the draining LN via afferent lymphatic vessels. The LN volume expands, presumably to accommodate the influx of cells and lymph exiting the inflamed synovium.
Other signs and symptoms of COPD may include: 1  Shortness of breath, especially during physical activities. 2  Wheezing. 3  Chest tightness.  Having to clear your throat first thing in the morning, due to excess mucus in your 1  lungs. A chronic cough that may produce mucus (sputum) that may be clear, white, yellow or greenish.
For people with COPD, having more shortness of breath than usual can be a sign of an acute exacerbation, or COPD flare-up. Shortness of breath can also be a symptom of a respiratory illness, such as: Respiratory infection (acute bronchitis) Pneumonia; Flu; Can shortness of breath be treated? 1,3