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The most common cause of intrauterine growth restriction is an abnormality in the placenta. A placental abnormality can cause intrauterine growth restriction because the fetus may become malnourished.Some other potential causes include: 1  Congenital or chromosomal abnormalities. 2  Heart disease.3  Diabetes.he most common cause of intrauterine growth restriction is an abnormality in the placenta. A placental abnormality can cause intrauterine growth restriction because the fetus may become malnourished. Some other potential causes include: 1  Congenital or chromosomal abnormalities. 2  Heart disease. 3  Diabetes.
What causes UPJ obstruction? Many UPJ problems may occur before birth, as enlargement of the kidney (hydronephrosis) can be seen on a prenatal ultrasound. The stagnation of urine caused by the UPJ blockage can lead to infection. Older children may have pain related to the blockage. Sometimes the blockage can cause kidney stones to form. The obstruction is usually due to an abnormality in the development of the muscle at the UPJ. What tests are needed? Ultrasonography, computerized tomography (CT) and intravenous pyelogram (IVP) will show the hydronephrosis related to a UPJ obstruction â but may not necessarily prove that the enlargement of the system is due to blockage.