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Ibuprofen is not safe for continuous, daily, long-term use due to its affect on the liver, kidneys and blood pressure.Watch pain management expert Devi Nampiaparampil, MD, explain how too much ibuprofen can have a negative impact over time.t can also increase the risk of bleeding in the stomach. Your doctor will need to regularly test your urine and blood if you are taking ibuprofen long-term. Over-the-counter ibuprofen should not be used for more than 10 days to treat body aches, unless directed to do so by your doctor.
Ibuprofen is a phenylpropionic acid NSAID introduced into the United States in 1974 as a prescription product intended to treat arthritic conditions at daily doses of up to 2400 mg. It was subsequently approved for daily doses of up to 3200 mg/day, and then as a prescription drug to treat mild to moderate pain in 1978. Since it became available to consumers in 1984, over 100 billion 200 mg tablets of ibuprofen have been sold OTC in the United States alone.