Multiple myeloma is staged by estimating the myeloma tumor cell mass on the basis of the amount of monoclonal (or myeloma) protein (M protein) in the serum and/or urine, along with various clinical parameters, such as hemoglobin and serum calcium concentrations, the number of lytic bone lesions, and the presence or absence of renal failure.
At present, daylight saving time in the United States. 1  begins at 2:00 a.m. on the second Sunday of March and. 2  ends at 2:00 a.m. on the first Sunday of November.
As of 2007, daylight time begins in the United States on the second Sunday in March and ends on the first Sunday in November. On the second Sunday in March, clocks are set ahead one hour at 2:00 a.m. local standard time (which becomes 3:00 a.m. local daylight time).ot all places in the U.S. observe daylight time. In particular, Hawaii and most of Arizona do not use it. The most recent change to local daylight time policy was in 2006, when Indiana adopted the use of daylight time state-wide.