These problems can be mitigated through the process of design, which is an intellectual approach that emphasizes empathy, abductive reasoning, and rapid prototyping. Horst Rittel, one of the first to formalize a theory of wicked problems, cites ten characteristics of these complicated social issues Rittel, Horst. Dilemmas in a General Theory of Planning.. Policy Sciences, 1973: 155-169.
Changes in blood pressure and volume are not nearly as sensitive a stimulator as increased osmolarity, but are nonetheless potent in severe conditions. For example, Loss of 15 or 20% of blood volume by hemorrhage results in massive secretion of antidiuretic hormone.
There is a direct correlation between your exercise intensity and the amount of thyroid hormone you produce. In other words, low thyroid levels are associated with low-intensity exercise, and as you increase your intensity level, your thyroid levels increase too. Exercise performed at the anaerobic threshold causes prominent changes in hormone values, and they continued to rise up to 90% of max heart rate [2].