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Silver sulfadiazine (INN, or silvadene) is a topical sulfonamide / silver antibacterial used as a topical cream on burns.Evidence regarding its usefulness in burns is poor.Tentative evidence has found that silver sulfadiazine may increase healing times â wounds may take longer to heal if treated with this drug, so it is not recommended by the authors of a Cochrane review.Silver sulfadiazine is typically delivered in a cream or aqueous suspension.entative evidence has found that silver sulfadiazine may increase healing times â wounds may take longer to heal if treated with this drug, so it is not recommended by the authors of a Cochrane review.
Silver sulfadiazine (Silvadene, SSD, SSD AF, Thermazene) cream is applied to the skin to treat and prevent infections from second or third-degree burns. Silvadene has few side effects because it's applied to the skin. The cream is not recommended for infants under 2 months of age.