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Sclerodermaâs main types are localized and systemic. Localized means the disease affects only certain parts of the body. Systemic means it can affect the whole body. 1  The localized type often affects only skin tissues. 2  It does not harm major organs.3  It may get better or go away without help.4  But it can be severe in some people and can leave skin damage.ocalized means the disease affects only certain parts of the body. Systemic means it can affect the whole body. 1  The localized type often affects only skin tissues. 2  It does not harm major organs. 3  It may get better or go away without help. 4  But it can be severe in some people and can leave skin damage.
Scleroderma causes the body to produce too much collagen. Collagen is a protein that makes up connective tissues, such as the skin. Too much collagen can make the skin stretch, harden and thicken, and can also cause damage to internal organs, such as the heart, lungs and kidneys.There are 2 types of scleroderma: localized and systemic.Localized scleroderma affects the skin only.oo much collagen can make the skin stretch, harden and thicken, and can also cause damage to internal organs, such as the heart, lungs and kidneys. There are 2 types of scleroderma: localized and systemic.