Multiple myeloma is staged by estimating the myeloma tumor cell mass on the basis of the amount of monoclonal (or myeloma) protein (M protein) in the serum and/or urine, along with various clinical parameters, such as hemoglobin and serum calcium concentrations, the number of lytic bone lesions, and the presence or absence of renal failure.
At present, daylight saving time in the United States. 1  begins at 2:00 a.m. on the second Sunday of March and. 2  ends at 2:00 a.m. on the first Sunday of November.
Updated March 24, 2017. Daylight Saving Time begins in the U.S. every year on the second Sunday in March. It happens in the wee hours of the morning, when many of us are typically asleep: 2 a.m. It ends on the first Sunday in November, also two hours after midnight.