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Gray matter serves as the message processing centers of the brain and is in charge of the brainâs conscious thought. While gray matter is located on the outside of the brain and the inside of the spinal cord, white matter follows the opposite pattern. It is located within the brain and outside of the spinal cord. In humans, distribution of white and gray matter varies between the sexes.
The exterior of the brain stem consists of white matter that conducts nerve signals within the brain stem and to the spinal cord and other regions of the brain. Masses of gray matter, known as nuclei, perform the processing role of the brain stem. The reticular formation, a network of mixed gray and white matter, extends throughout the interior of the brain stem and plays an important role in stimulation of the cerebrum and the muscles of the body.