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1 The most common form is peripheral neuropathy, which mainly affects the feet and legs. 2  Sciatica is pain, tingling, or numbness produced by an irritation of the sciatic nerve. 3  Sciatica is a pain in the leg due to irritation of the sciatic nerve.
The close approximation of the sciatic nerve is the reason that increased tone of the piriformis muscle could cause irritation to the sciatic nerve. Irritation to the sciatic nerve in patients with left psoas syndrome often causes pain that radiates down the back of the right leg and stops at the knee.