In the initial âexpandingâ phase, lymphatic fluid flows at an increased rate and volume from an affected joint to the draining LN via afferent lymphatic vessels. The LN volume expands, presumably to accommodate the influx of cells and lymph exiting the inflamed synovium.
COPD exacerbation. Many people with COPD have attacks called flare-ups or exacerbations (say egg-ZASS-er-BAY-shuns). This is when your usual symptoms quickly get worse and stay worse. A COPD flare-up can be dangerous, and you may have to go to the hospital. Symptoms include: Coughing up more mucus than usual. A change in the color or thickness of that mucus. More shortness of breath than usual. Greater tightness in your chest.
According to the Global Initiative for Obstructive Lung Disease, the hallmark symptoms of COPD are progressively worsening dyspnea, chronic cough and sputum production. However, cough and sputum production may be present long before airflow limitation, one of the primary characteristics of COPD, develops.