The DCN includes a practice residency, so it is important to determine State Authorization of Distance Education and if the applicant will be able to do a residency in his or her home state or may have to do such elsewhere. Please see the UNF State Authorization Status website for more information and updates.
Here, we provide a brief overview of NF-kB biology and discuss the role of NF-kB in mediating theanti-inflammatory effects of tocotrienolsThe NF-kB family of transcription factors is a central player in the regulation of inflammation and immuneresponses.ONCLUSIONS ANDFUTURE DIRECTIONS Overall, available studies are consistent with a role fortocotrienols in reducing NF-kB induction and, thereby, NF-kBâdependent induction of pro-inflammatory cytokine genes,cell cycle regulators, anti-apoptotic genes, and cell adhesionmolecules.
Proteasome-dependent degradation of the IÎºB proteins results in the liberation of NF-ÎºB, allowing this transcription factor to accumulate in the nucleus where it activates the expression of specific genes (1) involved in immune and inflammatory responses and in cell growth control.