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Description of Trazodone. Trazodone: oral antidepressant (trade name Desyrel) that is a nontricyclic drug used as a sedative. Trazodone: A synthetic triazolopyridine derivative, antidepressant and sedative Trazodone acts as a serotonin uptake inhibitor, chemically unrelated to tricyclic, tetracyclic, or other antidepressants.
Trazodone 100 Mg Tablets. Trazodone hydrochloride (Desyrel Â®) is a prescription drug that is approved to treat depression, also called major depression or clinical depression. It comes in the form of tablets and is taken by mouth, usually one to three times a day. Currently, only generic trazodone is available for sale.