Multiple myeloma is staged by estimating the myeloma tumor cell mass on the basis of the amount of monoclonal (or myeloma) protein (M protein) in the serum and/or urine, along with various clinical parameters, such as hemoglobin and serum calcium concentrations, the number of lytic bone lesions, and the presence or absence of renal failure.
At present, daylight saving time in the United States. 1  begins at 2:00 a.m. on the second Sunday of March and. 2  ends at 2:00 a.m. on the first Sunday of November.
Daylight saving time 2015 will begin on Sunday, March 8 at 2:00 a.m. For most, daylight saving time is an exciting sign of spring that comes with a slightly sleepy Monday. But if you're not a morning person to begin with, your mood and productivity can take a dive.