Up to 40% of northeastern Asians experience flushing and elevated heart rate after drinking even minimal amounts of alcohol, due to accumulation of acetaldehyde. This is because of a mutation in acetaldehyde dehydrogenase (ALDH2), the enzyme that converts acetaldehyde to acetate.
When you use Outlook, the operating system saves your files in the \Documents and Settings\ directory for your user name. This directory saves some user-specific configurations, including the contact files used in your Outlook installation. Each Outlook file can be identified by its extension. Contacts are saved with the \.pab\ file extension.
An OST file (.ost) is an offline folder file in Microsoft Outlook. Offline folders make it possible for the user to work offline and then to synchronize changes with the Exchange server the next time they connect. The ability to work offline is useful in environments with limited or unreliable connectivity.