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The most common cause of intrauterine growth restriction is an abnormality in the placenta. A placental abnormality can cause intrauterine growth restriction because the fetus may become malnourished.Some other potential causes include: 1  Congenital or chromosomal abnormalities. 2  Heart disease.3  Diabetes.he most common cause of intrauterine growth restriction is an abnormality in the placenta. A placental abnormality can cause intrauterine growth restriction because the fetus may become malnourished. Some other potential causes include: 1  Congenital or chromosomal abnormalities. 2  Heart disease. 3  Diabetes.
Intrauterine hypoxia occurs when the fetus is deprived of an adequate supply of oxygen. It may be due to a variety of reasons such as prolapse or occlusion of the umbilical cord, placental infarction and maternal smoking.Intrauterine growth restriction (IUGR) may cause or be the result of hypoxia.Intrauterine hypoxia can cause cellular damage that occurs within the central nervous system (the brain and spinal cord). This results in an increased mortality rate, including an increased risk of sudden infant death syndrome (SIDS).ntrauterine hypoxia can cause cellular damage that occurs within the central nervous system (the brain and spinal cord). This results in an increased mortality rate, including an increased risk of sudden infant death syndrome (SIDS).