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Description of Trazodone. Trazodone: oral antidepressant (trade name Desyrel) that is a nontricyclic drug used as a sedative. Trazodone: A synthetic triazolopyridine derivative, antidepressant and sedative Trazodone acts as a serotonin uptake inhibitor, chemically unrelated to tricyclic, tetracyclic, or other antidepressants.
Trazodone was approved by the FDA in 1982. PRESCRIBED FOR: Trazodone is primarily used for the treatment of depression. It is sometimes prescribed as a sedative, and also is used in combination with other drugs for the treatment of panic attacks, aggressive behavior, agoraphobia, and cocaine withdrawal. Medically Reviewed by a Doctor on 3/27/2015.