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epidermis. n. 1. (Biology) Also called: cuticle the thin protective outer layer of the skin, composed of stratified epithelial tissue. 2. (Anatomy) the outer layer of cells of an invertebrate.3. (Botany) the outer protective layer of cells of a plant, which may be thickened by a cuticle.orneum, horny layer, stratum corneum-the outermost layer of the epidermis consisting of dead cells that slough off. stratum lucidum-the layer of epidermis immediately under the stratum corneum in the skin of the palms and soles.
The epidermis is the outer layer of the skin made of epithelial tissue. The epidermis contains keratin-secreting cells (keratinocytes). Keratin is an insoluble protein contained in the surface of the skin, which provides protection and impermeability.