The average annual salary for physical therapist in the United States is $86,520, which is 103% higher than the average income of Americans.The median pay for PTs is $7,210 per month, $1,663 per week and $41.59 per hour.A certified PT can earn at least $60,600 a year, which means $29.13 per hour and $5,050 per month.alary Range. A certified PT can earn at least $60,600 a year, which means $29.13 per hour and $5,050 per month. A senior can make an average of $120,000 a year depending on location, experience, etc.
A ligand that can bind to a receptor, alter the function of the receptor, and trigger a physiological response is called an agonist for that receptor. Agonist binding to a receptor can be characterized both in terms of how much physiological response can be triggered and in terms of the concentration of the agonist that is required to produce the physiological response.
A ligand binds its receptor through a number of specific weak non-covalent bonds by fitting into a specific binding site or pocket. In situations where even low concentrations of a ligand will result in binding of most of the cognate receptors, the receptor affinity is considered to be high.Low receptor affinity occurs when a high concentration of the ligand is required for most receptors to be occupied.The dissociation constant (Kd,) is the concentration of ligand required to occupy one half of the total available receptors. This measurement of receptor affinity is often in the range of 10-4 to 10-9 mM.With prolonged exposure to a ligand (and occupation of the receptor) cells often become desensitized.he dissociation constant (Kd,) is the concentration of ligand required to occupy one half of the total available receptors. This measurement of receptor affinity is often in the range of 10-4 to 10-9 mM. With prolonged exposure to a ligand (and occupation of the receptor) cells often become desensitized.