Multiple myeloma is staged by estimating the myeloma tumor cell mass on the basis of the amount of monoclonal (or myeloma) protein (M protein) in the serum and/or urine, along with various clinical parameters, such as hemoglobin and serum calcium concentrations, the number of lytic bone lesions, and the presence or absence of renal failure.
At present, daylight saving time in the United States. 1  begins at 2:00 a.m. on the second Sunday of March and. 2  ends at 2:00 a.m. on the first Sunday of November.
Since 1986 the United States had observed Daylight Saving Time from the first Sunday in April through the last Sunday in October. The provisions of the bill call for Daylight Saving Time to begin three weeks earlier on the second Sunday in March and end on the first Sunday in November.