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Typhoid fever is treated with antibiotics which kill the Salmonella bacteria. Prior to the use of antibiotics, the fatality rate was 20%. Death occurred from overwhelming infection, pneumonia, intestinal bleeding, or intestinal perforation. With antibiotics and supportive care, mortality has been reduced to 1%-2%.
Save. Typhoid fever is caused by a resistant bacterium called Salmonella typhi. Because the bacteria is primarily passed through fecal matter, typhoid fever is more common in developing nations with poor water treatment and open sewage.ome of the earliest indications that you may have typhoid fever are if you experience a high fever (up to 104 degrees F) along with weakness, headache, sore throat, stomach pain and diarrhea or constipation. A rash may appear on the trunk that typically resolves within 5 days. Creatas Images/Creatas/Getty Images.