These problems can be mitigated through the process of design, which is an intellectual approach that emphasizes empathy, abductive reasoning, and rapid prototyping. Horst Rittel, one of the first to formalize a theory of wicked problems, cites ten characteristics of these complicated social issues Rittel, Horst. Dilemmas in a General Theory of Planning.. Policy Sciences, 1973: 155-169.
Increased ADH levels are often associated with SIADH, which may be due to a variety of cancers, including leukemia, lymphoma, and cancers of the lung, pancreas, bladder, and brain. Levels of ADH may be greatly increased with such cancers.
Levels are also high in women who have high blood pressure or diabetes. Estrogen levels rise during a healthy pregnancy, and increased estrogen levels may be seen with tumors of the ovaries, testes, or adrenal glands. Some drugs can also increase estrogen levels.