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When the ventricles contract, atrioventricular valves close to prevent blood from flowing back into the atria. When the ventricles relax, semilunar valves close to prevent blood from flowing back into the ventricles.
The mitral valve regulates the flow of oxygen rich blood from the lungs to pass from the left atrium to the left ventricle.There are two main diseases or malfunctions of heart valves: regurgitation (valve does not close tightly) and stenosis (valve does not open fully).itral Valve Regurgitation, Stenosis, and Prolapse. The mitral valve is referred to as atrioventricular valves because it is located between the left atria and the left ventricle.