duete; see due, ty 2 ]. syn: duty, obligation refer to something a person feels bound to do. A duty often applies to what a person performs in fulfillment of the permanent dictates of conscience, piety, right, or law: one's duty to tell the truth; a parent's duty to raise children properly.
Mutations in the RB1 gene are responsible for most cases of retinoblastoma. RB1 is a tumor suppressor gene, which means that it normally regulates cell growth and keeps cells from dividing too rapidly or in an uncontrolled way.
when retinoblastoma is associated with a gene mutation that occurs in all of the body s cells it is known as germinal retinoblastoma people with this form of retinoblastoma also have an increased risk of developing several other cancers outside the eyeutations in the rb1 gene are responsible for most cases of retinoblastoma rb1 is a tumor suppressor gene which means that it normally regulates cell growth and keeps cells from dividing too rapidly or in an uncontrolled way