These problems can be mitigated through the process of design, which is an intellectual approach that emphasizes empathy, abductive reasoning, and rapid prototyping. Horst Rittel, one of the first to formalize a theory of wicked problems, cites ten characteristics of these complicated social issues Rittel, Horst. Dilemmas in a General Theory of Planning.. Policy Sciences, 1973: 155-169.
Increased ADH levels are often associated with SIADH, which may be due to a variety of cancers, including leukemia, lymphoma, and cancers of the lung, pancreas, bladder, and brain. Levels of ADH may be greatly increased with such cancers.
This stimulates renin release by the kidney, which increases circulating angiotensin II (AII) and aldosterone. These hormones increase blood volume by enhancing renal reabsorption of sodium and water. Increased AII also causes systemic vasoconstriction and enhances sympathetic activity.ncreased secretion of aldosterone generally results from adrenal adenoma or adrenal hyperplasia. Increased circulating aldosterone causes renal retention of sodium and water (see figure), so blood volume and arterial pressure increase.