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Causes of urinary tract infections. The vast majority of UTI cases are caused by the bacterium Escherichia coli (E. coli), usually found in the digestive system. Chlamydia and Mycoplasma bacteria can infect the urethra but not the bladder.
1 The majority of urinary tract infections are caused by the E. Coli bacterium. 2  Common symptoms include a strong, frequent urge to urinate and a painful and burning sensation when urinating. 3  Urinary tract infection is usually diagnosed based on symptoms and testing of a urine sample.rinary tract infections are caused when microbes manage to get past the body's natural defenses. The vast majority of UTI cases are caused by the bacterium Escherichia coli (E. coli), usually found in the digestive system. Chlamydia and Mycoplasma bacteria can infect the urethra but not the bladder.