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Typhoid fever is treated with antibiotics which kill the Salmonella bacteria. Prior to the use of antibiotics, the fatality rate was 20%. Death occurred from overwhelming infection, pneumonia, intestinal bleeding, or intestinal perforation. With antibiotics and supportive care, mortality has been reduced to 1%-2%.
Take antibiotics. When you are first diagnosed with typhoid fever, your doctor will figure out how far along the disease has progressed. If the disease is diagnosed in its early stages, the common treatment is with antibiotics. He will prescribe your antibiotics, which you will take for one to two weeks. Some strains of the bacteria that cause typhoid fever have become very resistant to some antibiotics. This means that your doctor will do thorough laboratory tests to come up with the best treatment plan for the particular strain you have.