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The term ' Activated Partial Thromboplastin Time ( APTT ) ' derives from the original form of the test ( devised in 1953 ) in which only the phospholipid concentration of the test was controlled ( as opposed to the phospholipid and the surface activator concentrations ) and the name ' partial thromboplastin ' was applied at the time to phospholipid ...
The aPTT test uses blood which is decalcified to prevent clotting before the test begins. The plasma is separated by centrifugation. (Ionized) Calcium and activating substances are added to the plasma to start the intrinsic pathway of the coagulation cascade.