The looping of the template for the lagging strand enables a dimeric DNA polymerase III holoenzyme at the replication fork to synthesize both daughter strands. (Courtesy of A. Kornberg. From L. Stryer, Biochemistry, 4th ed.he 3â²âââ5â² exonuclease action of DNA polymerase III. Note that this exonuclease activity takes place at the 3â² end of the growing strand (and is therefore 3â²âââ5â²). The coordination of exonuclease activity with strand growth helps to explain why replication is in the 5â²âââ3â² direction.
McAllen is the twenty-first most populous city in Texas and the largest city in Hidalgo County, Texas. It is located at the southern tip of Texas in the Rio Grande Valley (not a geographical valley) and is part of the Southern United States.
Homefacts City Report. Mcallen is located in Hidalgo County, TX. The population is 134,729, making Mcallen the largest city in Hidalgo County. There are 46 public schools in Mcallen with an average Homefacts rating of B-. The total crime rate for Mcallen is very low, and there are 202 registered sex offenders residing in the city.