In the initial âexpandingâ phase, lymphatic fluid flows at an increased rate and volume from an affected joint to the draining LN via afferent lymphatic vessels. The LN volume expands, presumably to accommodate the influx of cells and lymph exiting the inflamed synovium.
Other signs and symptoms of COPD may include: 1  Shortness of breath, especially during physical activities. 2  Wheezing. 3  Chest tightness.  Having to clear your throat first thing in the morning, due to excess mucus in your 1  lungs. A chronic cough that may produce mucus (sputum) that may be clear, white, yellow or greenish.
Increased Shortness of Breath. BURGER/Getty Images. Shortness of breath, or dyspnea, is one of the hallmark symptoms of COPD. However, if it begins to worsen, this could be a sign that you are developing a lung infection and need to contact your doctor.