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The human brain is the central organ of the human nervous system. The human brain, with the spinal cord, makes up the central nervous system. The brain consists of the the cerebrum, its largest part, the brainstem and the cerebellum. The brain is the organ that controls most of the activities of the body.
The Biggest Part: the Cerebrum. The biggest part of the brain is the cerebrum. The cerebrum makes up 85% of the brain's weight, and it's easy to see why. The cerebrum is the thinking part of the brain and it controls your voluntary muscles â the ones that move when you want them to. So you can't dance â or kick a soccer ball â without your cerebrum.