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The small intestine is where most chemical digestion takes place. Many of the digestive enzymes that act in the small intestine are secreted by the pancreas and enter the small intestine via the pancreatic duct.he small intestine is where most chemical digestion takes place. Many of the digestive enzymes that act in the small intestine are secreted by the pancreas and enter the small intestine via the pancreatic duct.
Most chemical digestion takes place in the duodenum by chemicals secreted by the liver, pancreas and small intestine. The other two sections of the small intestine, the jejunum and the ileum, absorb food molecules by way of the villi directly into the blood stream.