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Read More. Metformin has been known to cause kidney and liver problems, but this does not happen in all patients, and there is some evidence there is a co-factor, in development of damage, such as alcoholism, or a combination of other drugs. The national database PUBMED has the studies.
Some examples of common metformin side effects include diarrhea, nausea, and gas. Also, there are some more serious side effects of metformin that you should report immediately to your healthcare provider, such as symptoms of high blood sugar, chest pain, or signs of an allergic reaction.