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If kidneys don't work properly, harmful substances build up in the body, blood pressure can rise, and too much fluid can collect in the body's tissues, which leads to swelling, called edema. If your kidneys fail, you will need dialysis or a kidney transplant to take over their job.
Kidney disease often can get worse over time and may lead to kidney failure. If your kidneys fail, you will need dialysis or a kidney transplant to maintain your health. The sooner you know you have kidney disease, the sooner you can make changes to protect your kidneys. More information is provided in the NIDDK health topic, The Kidneys and How They Work.