N2 nicotinic receptors are found in the brain, plus the autonomic and parasympathetic nervous systems [1]. Different subunits make up these two types of nicotinic receptor, which is why we consider them separately. Muscarinic receptors have a different mechanism of action.
Your body weight can regularly fluctuate, but the persistent, unintentional loss of more than 5% of your weight over 6 to 12 months is usually a cause for concern. You should pay particular attention if you experience other symptoms, such as tiredness, loss of appetite and a change in your toilet habits.
One of the many contributions and causes of weight gain is the inappropriate use of certain drugs or supplements that affect the normal metabolic or biochemical activities of the body, leading to fluctuations in body weight. One such drug is prednisone - a chemical derivative of the endogenous hormone cortisol.