N2 nicotinic receptors are found in the brain, plus the autonomic and parasympathetic nervous systems [1]. Different subunits make up these two types of nicotinic receptor, which is why we consider them separately. Muscarinic receptors have a different mechanism of action.
Your body weight can regularly fluctuate, but the persistent, unintentional loss of more than 5% of your weight over 6 to 12 months is usually a cause for concern. You should pay particular attention if you experience other symptoms, such as tiredness, loss of appetite and a change in your toilet habits.
Rapid unintentional weight gain may be due to medication side effects. Many cases of unintentional weight gain are harmless. But some symptoms experienced along with rapid weight gain may signal a medical emergency. What causes unintentional weight gain? Pregnancy. The most common cause of unintentional weight gain is pregnancy. But many women do intentionally eat more to support the growth of the baby. During pregnancy, most women put on weight as the baby grows.