Even the bra industry has admitted that a bra will NOT keep breasts from sagging, and that it will only hold them into a position that a particular bra design is designed to do, while the bra is being worn, and when the bra is removed, the breasts will no longer retain that position.
Abstract. Drugs may interact with other drugs or any diet or dietary supplement taken at the same time. Interactions may be pharmacodynamic in which interaction is close to the target organ and involves direct antagonism or addition of pharmacological properties.rug interactions are usually described as pharmacodynamic (where changes in drug action occur in the area of the target tissue) or pharmacokinetic (when one drug affects the absorption, distribution or excretion of another).
Pharmacodynamics, with pharmacokinetics (what the body does to a drugâsee Pharmacokinetics), helps explain the relationship between the dose and response, ie, the drug's effects. The pharmacologic response depends on the drug binding to its target. The concentration of the drug at the receptor site influences the drugâs effect. A drugâs pharmacodynamics can be affected by physiologic changes due to disorders, aging, or other drugs. Disorders that affect pharmacodynamic responses include genetic mutations, thyrotoxicosis, malnutrition, myasthenia gravis, Parkinson disease, and some forms of insulin -resistant diabetes mellitus.