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When levels fall too low, brain cells cannot generate enough energy to function properly. As a result, Korsakoff syndrome may develop. Korsakoff syndrome is most commonly caused by alcohol misuse, but can also be associated with AIDS, chronic infections, poor nutrition and certain other conditions.
Definition. Wernicke-Korsakoff Syndrome (WKS) is a neurological disorder. Wernickeâs Encephalopathy and Korsakoffâs Psychosis are the acute and chronic phases, respectively, of the same disease. WKS is caused by a deficiency in the B vitamin thiamine.Thiamine plays a role in metabolizing glucose to produce energy for the brain.ernickeâs Encephalopathy and Korsakoffâs Psychosis are the acute and chronic phases, respectively, of the same disease. WKS is caused by a deficiency in the B vitamin thiamine. Thiamine plays a role in metabolizing glucose to produce energy for the brain.