On May 5, 2014, it was announced John Krasinski would direct the film, with Krasinski, Anna Kendrick, Margo Martindale and Richard Jenkins joining the cast.
Epstein-Barr virus (EBV) is a ubiquitous herpesvirus spread by human contact with no know environmental reservoir. Antibodies are detected in 90 to 95% of adults worldwide. EBV infection is subclinical in 90% of children.
The Epstein-Barr virus (EBV), a member of the herpesvirus family, is found throughout the world. Studies show that up to 95% of all adults have antibodies against this common virus, meaning that they were infected at some point in their lives.