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If kidneys don't work properly, harmful substances build up in the body, blood pressure can rise, and too much fluid can collect in the body's tissues, which leads to swelling, called edema. If your kidneys fail, you will need dialysis or a kidney transplant to take over their job.
When chronic kidney disease progresses to end stage renal disease (stage 5 kidney disease), patients will need dialysis to help clear the blood of toxins and fluid usually processed by the kidneys.The two main dialysis modalities are hemodialysis and peritoneal dialysis.emodialysis involves using a machine that circulates your blood through a filter to help remove fluid and waste. Hemodialysis is most frequently done in a dialysis unit three times a week for three to four hours each time. Dialysis staff will monitor your dialysis while you are on the machine.