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The small intestine is where most chemical digestion takes place. Many of the digestive enzymes that act in the small intestine are secreted by the pancreas and enter the small intestine via the pancreatic duct.he small intestine is where most chemical digestion takes place. Many of the digestive enzymes that act in the small intestine are secreted by the pancreas and enter the small intestine via the pancreatic duct.
Chemical digestion occurs int he stomach where acids break down the food turning it into chyme, and also happens in the mouth where saliva mixed with enzymes break food into b â¦ olus.