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Cholecystitis is inflammation of the gallbladder, a small organ near the liver that plays a part in digesting food. Normally, fluid called bile passes out of the gallbladder on its way to the small intestine. If the flow of bile is blocked, it builds up inside the gallbladder, causing swelling, pain, and possible infection.
According to The Merck Manual Home Health Handbook, gallbladder sludge is often caused by the accumulation of substances such as cholesterol, calcium compounds and bilirubin. These materials stay in the gallbladder but don't form stones. Sometimes the sludge is caused by pregnancy, and once the baby is born, the sludge leaves the organ. If sludge remains, it often forms gallstones or passes out of the gallbladder and blocks digestive system ducts.