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Bilirubin (formerly referred to as haematoidin) is the yellow breakdown product of normal heme catabolism, caused by the body's clearance of aged red blood cells which contain hemoglobin.Bilirubin is excreted in bile and urine, and elevated levels may indicate certain diseases.ilirubin (formerly referred to as haematoidin) is the yellow breakdown product of normal heme catabolism, caused by the body's clearance of aged red blood cells which contain hemoglobin.
Reference Range. Bilirubin is a tetrapyrrole and a breakdown product of heme catabolism. Most bilirubin (70%-90%) is derived from hemoglobin degradation and, to a lesser extent, from other hemo proteins. In the serum, bilirubin is usually measured as both direct bilirubin (DBil) and total-value bilirubin (TBil).