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Opana ER. OXYMORPHINE is a pain reliever. It is used to treat moderate to severe pain that lasts for more than a few days. It is used by people who have been taking an opioid or narcotic pain medicine.
Half-life has a direct effect on how long withdrawal will last as well as on how long the substance will show up in drug tests. The half-life of Opana ER ranges from 9.4 hours to 11.3 hours, but there are some factors that can affect how long the drug actually remains in the system. These include: Version: Opana ER is an extended-release version of the drug, which means it has a longer half-life.