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Cholecystitis is inflammation of the gallbladder, a small organ near the liver that plays a part in digesting food. Normally, fluid called bile passes out of the gallbladder on its way to the small intestine. If the flow of bile is blocked, it builds up inside the gallbladder, causing swelling, pain, and possible infection.
The gallbladder is a small pouch that sits just under the liver. The gallbladder stores bile produced by the liver. After meals, the gallbladder is empty and flat, like a deflated balloon. Cholecystitis: Inflammation of the gallbladder, often due to a gallstone in the gallbladder. 2  Cholecystitis causes severe pain and fever, and can require surgery when inflammation continues or recurs. 3  Gallbladder cancer: Although rare, cancer can affect the gallbladder.