On May 5, 2014, it was announced John Krasinski would direct the film, with Krasinski, Anna Kendrick, Margo Martindale and Richard Jenkins joining the cast.
Epstein-Barr virus (EBV) is a ubiquitous herpesvirus spread by human contact with no know environmental reservoir. Antibodies are detected in 90 to 95% of adults worldwide. EBV infection is subclinical in 90% of children.
Epstein-Barr virus (EBV) is a Î³ herpesvirus that persists for life in humans as a latent infection of B cells under the immunosurveillance of CD8 + Î±Î² cytotoxic T lymphocytes (CTLs) (reviewed in Khanna and Burrows 1). An interesting enigma in EBV biology is the variable nature of primary infection.