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In addition to an increase level of TSH above 2.5 mU/L during the first trimester, and above 3 mU/L in the second and third trimester, a decrease fT4 concentration (also using reference range for pregnant women) will help clinicians diagnose overt hypothyroidism during pregnancy.
TSH Levels in Pregnancy. Thyroid Stimulating Hormone (TSH) is a measure taken from a blood sample to test thyroid functioning. High TSH levels above the reference range are interpreted as an underactive thyroid, known as hypothyroidism. Low TSH levels below the reference range are interpreted as an overactive thyroid, hyperthyroidism.