Removal of a salivary gland does not produce a dry mouth, called xerostomia. However, radiation therapy to the mouth can cause the unpleasant symptoms associated with reduced salivary flow. Your doctor can prescribe medication or other conservative treatments that may reduce the dryness in these instances.
Harlequin Ichthyosis Causes. The harlequin ichthyosis is known to be genetic in nature. The ABC 12 gene, which directs the protein production that is necessary to have a normal skin growth, is being mutated which leads to this severe skin disorder. It is a gene that is responsible for the transportation of lipid.
Mutations in the Tay-Sachs Chromosome. Tay-Sachs disease is caused by mutations in the HEXA gene. More than 95 mutations that cause the disease have been identified. These mutations reduce or eliminate the activity of the enzyme beta-hexosaminidase A, preventing the normal breakdown of GM2 ganglioside in the brain and spinal cord.