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When levels fall too low, brain cells cannot generate enough energy to function properly. As a result, Korsakoff syndrome may develop. Korsakoff syndrome is most commonly caused by alcohol misuse, but can also be associated with AIDS, chronic infections, poor nutrition and certain other conditions.
Wernicke-Korsakoff syndrome (WKS) is a type of brain disorder caused by a lack of vitamin B1. The syndrome is actually two separate conditions that can occur at the same time.Usually youâll experience symptoms of Wernickeâs encephalopathy first.igns of Korsakoff psychosis tend to follow as the Wernickeâs symptoms wane. If Wernickeâs disease is treated quickly and effectively, Korsakoff syndrome may not develop (Mayo Clinic). Korsakoff psychosis is the result of chronic brain damage. Korsakoff syndrome affects the areas of your brain that control memory.