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Acute HIV Rash: A Symptom of HIV Infection. When people are first infected with HIV, they may experience an acute, 'flu-like' illness called a 'seroconversion illness,' about 2-4 weeks after being infected. The HIV rash is a symptom of this condition. The rash will mostly affect the upper part of the body and will probably be found on the shoulder, chest area (as in the picture below), face, torso and palms of the hands.
HIV rash usually causes blotches and spots on the skin, which are red in people with fair skin, or dark purplish in people with dark skin. The spots may be flat or slightly raised, and tend to be very itchy. The symptoms vary between patients - some get a very severe rash which covers a large area, others only have a very minor rash. In most cases, the HIV rash occurs during seroconversion (the time when the infection becomes detectable via blood tests).