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Common Cancers That Metastasize to the Bones. Bones, lungs, and the liver are the most common places for cancer cells to spread, or metastasize.. Once in the bone, these cancer cells can form new metastatic tumors.
Answers from Erik P. Castle, M.D. In theory, prostate cancer cells can spread anywhere in the body. In practice, though, most cases of prostate cancer metastasis occur in the lymph nodes and the bones. Prostate cancer metastasis occurs when cells break away from the tumor in the prostate. The cancer cells can travel through the lymphatic system or the bloodstream to other areas of the body. More commonly prostate cancer metastasis can occur in the: Bones.