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It is also possible for depression to develop as a result of these disorders. Diseases like cancer, heart disease, stroke, diabetes and Parkinson's disease can cause depression. The depression symptoms can be worsened by the presence of the disease and the disease symptoms can be worsened by the presence of depression. In these instances treating the depression can alleviate the symptoms associated with the disease. Risk factors for depression. Depression is a severe mental illness which can afflict anyone, even children, at any stage of their life. There are however prevalent risk factors associated with depression. These risk factors include:
Depression results from a complex interaction of social, psychological and biological factors. People who have gone through adverse life events (unemployment, bereavement, psychological trauma) are more likely to develop depression. Globally, an estimated 350 million people of all ages suffer from depression. 2  Depression is the leading cause of disability worldwide, and is a major contributor to the overall global burden of disease. 3  More women are affected by depression than men. 4  At its worst, depression can lead to suicide.