History and Uses: Although calcium is the fifth most abundant element in the earth's crust, it is never found free in nature since it easily forms compounds by reacting with oxygen and water.Metallic calcium was first isolated by Sir Humphry Davy in 1808 through the electrolysis of a mixture of lime (CaO) and mercuric oxide (HgO).ther common compounds of calcium include: calcium sulfate (CaSO 4), also known as gypsum, which is used to make dry wall and plaster of Paris, calcium nitrate (Ca(NO 3) 2), a naturally occurring fertilizer and calcium phosphate (Ca 3 (PO 4) 2), the main material found in bones and teeth.
incretin: A gastrointestinal hormone causing an increase in the amount of insulin released from the beta cells of the islets of Langerhans after eating, even before blood glucose levels become elevated.
GLP-1 and DPP-4 inhibitors. Incretins are a group of metabolic hormones that stimulate a decrease in blood glucose levels. Incretins do so by causing an increase in the amount of insulin released from pancreatic beta cells of the islets of Langerhans after eating, before blood glucose levels become elevated.owever, oral administration of extracts of intestinal mucosa failed to help several patients with type 1 diabetes. In 1932, La Barre proposed the name incretin for a hormone extracted from the upper gut mucosa, which caused hypoglycemia, and proposed a possible therapy for diabetes.