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This unzipping takes place in both directions from the replication origins, creating a replication bubble. The replication is therefore said to be bi-directional. Once the two strands are separated a small piece of RNA, called an RNA primer, is attached to the DNA by an enzyme called DNA primase. These primers are the beginnings of all new DNA chains since the enzyme responsible for the copying of the DNA, DNA polymerase, can not start from scratch.
RNA is usually synthesized from DNA. The synthesis usually requires one or more enzymes like RNA polymerase. The DNA strand is used as a template or guide on which the RNA is formed. Since RNA forms the proteins, this is the way the DNA maintains the blue print for all proteins without leaving the nucleus. Transcription . Using the DNA strand as template, a long chain of nucleotides are formed. This is called transcription.