N2 nicotinic receptors are found in the brain, plus the autonomic and parasympathetic nervous systems [1]. Different subunits make up these two types of nicotinic receptor, which is why we consider them separately. Muscarinic receptors have a different mechanism of action.
Your body weight can regularly fluctuate, but the persistent, unintentional loss of more than 5% of your weight over 6 to 12 months is usually a cause for concern. You should pay particular attention if you experience other symptoms, such as tiredness, loss of appetite and a change in your toilet habits.
1 Overeating or inactivity as a result of depression can cause weight gain. 2  Some people lose weight as part of their depression. In turn, an improved appetite associated with improved mood may result in increased weight.  Adults generally tend to gain weight as they age, regardless of the medications they take.