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The small intestine is where most chemical digestion takes place. Many of the digestive enzymes that act in the small intestine are secreted by the pancreas and enter the small intestine via the pancreatic duct.he small intestine is where most chemical digestion takes place. Many of the digestive enzymes that act in the small intestine are secreted by the pancreas and enter the small intestine via the pancreatic duct.
Chemical digestion differs from mechanical digestion, which occurs in the mouth as the teeth grind and chew pieces of food. Some mechanical digestion also takes place in the stomach as the muscles churn food particles.hemical digestion breaks down carbohydrates, proteins and fats into sugars, amino acids and fatty acids that the body can absorb and use as fuel.