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When levels fall too low, brain cells cannot generate enough energy to function properly. As a result, Korsakoff syndrome may develop. Korsakoff syndrome is most commonly caused by alcohol misuse, but can also be associated with AIDS, chronic infections, poor nutrition and certain other conditions.
Wernicke-Korsakoff Syndrome cannot be diagnosed while a patient is in withdrawal, or experiencing medical complications from their alcohol abuse. A patient must be sober and still experiencing symptoms to be diagnosed with Wernicke-Korsakoff Syndrome.