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Bilirubin (formerly referred to as haematoidin) is the yellow breakdown product of normal heme catabolism, caused by the body's clearance of aged red blood cells which contain hemoglobin.Bilirubin is excreted in bile and urine, and elevated levels may indicate certain diseases.ilirubin (formerly referred to as haematoidin) is the yellow breakdown product of normal heme catabolism, caused by the body's clearance of aged red blood cells which contain hemoglobin.
Bilirubin (formerly referred to as haematoidin) is the yellow breakdown product of normal heme catabolism, caused by the body's clearance of aged red blood cells which contain hemoglobin. Bilirubin is excreted in bile and urine, and elevated levels may indicate certain diseases.ilirubin consists of an open chain of four pyrrole-like rings (tetrapyrrole). In heme, these four rings are connected into a larger ring, called a porphyrin ring. Bilirubin can be conjugated with a molecule of glucuronic acid which makes it soluble in water (see below). This is an example of glucuronidation.