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When levels fall too low, brain cells cannot generate enough energy to function properly. As a result, Korsakoff syndrome may develop. Korsakoff syndrome is most commonly caused by alcohol misuse, but can also be associated with AIDS, chronic infections, poor nutrition and certain other conditions.
Knowledge center. Wernicke-Korsakoff syndrome is directly caused by a thiamin deficiency and is linked to long-term (chronic) alcohol consumption-however, some patients who do not abuse alcohol may also develop this syndrome.ernickes encephalopathy-this is a type of brain damage in which the initial symptoms appear. The individual has abnormal gait and eye movements. Korsakoff syndrome-if Wernickes encephalopathy is left untreated the patient will start developing this psychiatric disorder, which includes dementia and psychosis.