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When levels fall too low, brain cells cannot generate enough energy to function properly. As a result, Korsakoff syndrome may develop. Korsakoff syndrome is most commonly caused by alcohol misuse, but can also be associated with AIDS, chronic infections, poor nutrition and certain other conditions.
The symptoms of Korsakoff syndrome often develop as the mental symptoms of Wernicke syndrome begin to lessen. Korsakoff syndrome is characterized by memory impairment, specifically short-term memory loss (i.e., the inability to form new memories).