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tunica exterÂ´na an outer coat, such as the fibroelastic coat of a blood vessel. tunica interÂ´na an inner coat or layer. tunica inÂ´tima the innermost coat of a blood vessel; called also Bichat's tunic. tunica meÂ´dia the muscular middle coat of a blood vessel.
Tunica intima. The tunica intima (New Latin inner coat), or intima for short, is the innermost tunica (layer) of an artery or vein. It is made up of one layer of endothelial cells and is supported by an internal elastic lamina. The endothelial cells are in direct contact with the blood flow. The tunicae of blood vessels are three layersâan inner layer (the tunica intima), a middle layer (the tunica media), and an outer layer (the tunica adventitia). In dissection, the inner coat (tunica intima) can be separated from the middle (tunica media) by a little maceration, or it may be stripped off in small pieces; but, because of its friability, it cannot be separated as a complete membrane.