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When levels fall too low, brain cells cannot generate enough energy to function properly. As a result, Korsakoff syndrome may develop. Korsakoff syndrome is most commonly caused by alcohol misuse, but can also be associated with AIDS, chronic infections, poor nutrition and certain other conditions.
Korsakoff's syndrome is a form of ARBD in which the main cause is a clear lack of thiamine. Korsakoff's syndrome is the most well-known form of ARBD and many people think that it is the most common or even only form. However, Korsakoff's syndrome is much less common than other forms of ARBD such as alcoholic dementia.