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In fact, we expect that across all humans, there are over 100 mutations at every single position in the human genome. And, here is the math to prove it: The average mutation rate in the human genome is 1.2 x10^-8 mutations per site per generation.This is pretty small, so in each person, we only expect to observe a handful of new mutations relative to their parents.But, that handful of mutations adds up when you think of how many people are on the earth.n fact, we expect that across all humans, there are over 100 mutations at every single position in the human genome. And, here is the math to prove it: The average mutation rate in the human genome is 1.2 x10^-8 mutations per site per generation.
1 Estimated total number of nucleotide pairs in a human cell: 6 x 10^9. 2  The average size of a human cell is 10 micrometers. 3  The average size of the nucleus in a human cell is 5 micrometers. 4  1 angstrom equals 0.0000000001 meters.5  10 billion angstroms equals 1 meter. Estimated total number of nucleotide pairs in a human cell: 6 x 10^9. 2  The average size of a human cell is 10 micrometers. 3  The average size of the nucleus in a human cell is 5 micrometers. 4  1 angstrom equals 0.0000000001 meters. 5  10 billion angstroms equals 1 meter.