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Elephantiasis is caused by obstruction of the lymphatic system, which results in the accumulation of a fluid called lymph in the affected areas. Functioning as part of the immune system, the lymphatic system helps to protect the body against infection and disease.
Leg swelling can be caused by progressive cirrhosis of the. liver. Cirrhosis of the liver is a complication of liver disease. which causes the loss of liver cells and scarring of this vital. organ. As the disease becomes severe, signals are sent to the. kidneys to cause them to retain salt and water in the body.