In situations where the concomitant use of clarithromycin with statins cannot be avoided, it is recommended to prescribe the lowest registered dose of the statin. Use of a statin that is not dependent on CYP3A metabolism (e.g. fluvastatin or pravastatin) should be considered (see section 4.5).
On the basis of these data, they assumed the ancient model of and estimated both a recent epoch of exponential growth and the population size before growth, pointing to growth starting 3.5 (2.9â4.1) kya at a rate of 3.4% (2.4â5.1%) per generation, resulting at 0.65 (0.30â2.87) millions individuals today (Figure 1b and Table 2).
Population of Prestonsburg, KY. Last official estimated population of Prestonsburg city (Floyd County**, Kentucky state) was 3,277 (year 2014) [1]. This was 0.001% of total US population and 0.07% of total Kentucky state population. Area of Prestonsburg city is 14.1 miÂ² (=36.5 kmÂ²) [6], in this year population density was 232.58 p/miÂ². If population growth rate would be same as in period 2010-2014 (+0.17%/yr), Prestonsburg city population in 2018 would be 3,299*.