Salbutamol was the first selective Î² 2 -receptor agonist to be marketed in 1968. It was first sold by Allen & Hanburys (UK) under the brand name Ventolin, and has been used for the treatment of asthma ever since. It was approved for use in the US by the Food and Drug Administration (FDA) in May 1982. The drug is usually manufactured and distributed as the sulfate salt salbutamol sulfate. Salbutamol is mostly taken by the inhaled route for direct effect on bronchial smooth muscle.
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