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Pleural thickening definition. Pleural thickening is a lung disease that describes a scarring, calcification, and/or thickening of the pleura (the lining surrounding the lungs) often as a consequence of the inhalation of asbestos into the lungs.f the asbestos fibres work their way into the pleura, they can cause the pleural thickening condition. Pleural thickening tends to cause sufferers a tightness of the chest or breathlessness which is attributed to the reduced lung function that the thickening causes.
The lining of the lungs, called the pleura or pleural membranes, consists of thin membranes that cover the lungs and provide protection and support. Some diseases can cause these membranes to thicken, often as a result of inflammation.Pleural thickening is commonly linked to mesothelioma and asbestosis, which are caused by asbestos exposure. The condition can also be caused by other diseases such as sarcoidosis and tuberculosis.ome diseases can cause these membranes to thicken, often as a result of inflammation. Pleural thickening is commonly linked to mesothelioma and asbestosis, which are caused by asbestos exposure. The condition can also be caused by other diseases such as sarcoidosis and tuberculosis.