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Until recent years, the standard treatment for a UTI was 10 days of amoxicillin, a penicillin antibiotic, but it is now ineffective against E. coli bacteria in many cases. A combination of amoxicillin-clavulanate (Augmentin) is sometimes given for drug-resistant infections.
A simple UTI can be treated with a short course of antibiotic meds. A 3-day course of antibiotics will often treat most uncomplicated UTIs. However, some infections may need to be treated for 5 days. Depending on the type of antibiotic used, you may take a single dose per day or up to 4 doses per day.