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A pancreaticoduodenectomy, pancreatoduodenectomy, Whipple procedure, or Kausch-Whipple procedure, is a major surgical operation involving the removal of the head of the pancreas, the duodenum, the proximal jejunum, gallbladder, and part of the stomach.
The Whipple procedure could be performed for any of the following reasons: 1  chronic pancreatitis. 2  pancreatic cancer (in the head of the pancreas) 3  cancer of the small intestine.  cholangiocarcinoma â (a cancer in the bile duct)