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Often, chronic kidney disease is diagnosed as a result of screening of people known to be at risk of kidney problems, such as those with high blood pressure or diabetes and those with a blood relative with CKD.
Diabetes and high blood pressure are the 2 most common causes and account for most cases. Many other diseases and conditions can damage the kidneys, including: 1  Autoimmune disorders (such as systemic lupus erythematosus and scleroderma)  Birth defects of the kidneys (such as polycystic kidney disease)