Causes of Ankle Pain. 1  Ankylosing Spondylitis Ankylosing spondylitis is a type of arthritis that causes chronic inflammation of the spine. 2  Arthritis Arthritis is inflammation of one or more joints. 3  Broken Bone (Types of Bone Fractures) A broken bone is a fracture.
Down syndrome is a chromosomal condition that is associated with intellectual disability, a characteristic facial appearance, and weak muscle tone (hypotonia) in infancy. All affected individuals experience cognitive delays, but the intellectual disability is usually mild to moderate.
Down syndrome (sometimes spelled âDownâs syndromeâ) is a genetic abnormality. It is the most common single cause of birth defects in the United States (NIH, 2012). This syndrome occurs because of an extra copy of chromosome 21. Your chromosomes contain your genetic material, and any problems with your chromosomes can cause serious physical and mental health problems.