Long-term treatment with pantoprazole may also make it harder for your body to absorb vitamin B-12, resulting in a deficiency of this vitamin. Talk with your doctor if you need long-term pantoprazole treatment and you have concerns about vitamin B-12 deficiency.ymptoms of a vitamin B-12 deficiency may develop slowly and include pale skin, weakness, tired feeling, shortness of breath, and a fast heart rate. Talk with your doctor if you need long-term pantoprazole treatment and you have concerns about vitamin B-12 deficiency.
Sustained Tempo Runs. This workout includes one block of running at tempo pace. That might be 20 minutes or 3 miles but thereâs no break or recovery in the middle of the effort. A simple example is a workout like this: 7 miles with miles 3-5 at tempo pace. Here you have a 7-mile run with the middle 3 miles at tempo. Sustained tempo runs should be capped at roughly 40 minutes â any longer and the effort becomes too difficult, bordering on a race effort.
So, a generic long run for someone who's goal marathon pace is 7:00 per mile might be that the first 12 miles of a long run will be at 7:30 to 8:00 per mile, then the pace over the last 6 miles will average 7:00 per mile with the last couple of miles at 6:15 to 6:30 pace and the last 400 meters very fast. say 'fast' because you will gradually increase to a faster and faster pace so that you finish the run running nearly as fast as you can for the last few miles. I learned this from Gabriele Rosa (arguably the world's greatest marathon coach).