Perinatal. Referring to the period of time surrounding an infant's birth, from the last two months of pregnancy to the first 28 days of life. The TORCH panel tests for perinatal infections.
1 CMT1 is commonly caused by a duplication of a gene on chromosome 17. This gene controls the production of your nervesâ protective myelin sheath. CMT1 is also caused by other gene defects.  CMT2 results from a defect in your peripheral nerve cellsâ axon. This is caused by a defect in your mitofusin 2 gene.
All types of Charcot-Marie-Tooth disease (CMT) cause degeneration of the peripheral nerves, leading to muscle weakness and some loss of sensation in the arms, legs, hands, and feet. These symptoms often first appear during adolescence or early adulthood, but can develop later in life, as well.t is named after the three doctors who described it in 1886: Jean Martin Charcot and Pierre Marie in Paris, and Howard Henry Tooth in Cambridge, England. Charcot-Marie-Tooth disease is also sometimes referred to as hereditary motor and sensory neuropathy (HMSN) or peroneal muscular atrophy.