Hypokinetic movements include: 1  Bradykinesia. 2  Freezing. 3  Rigidity. 4  Postural instability.
Mutations cause changes in the genetic code that lead to genetic variation and the potential to develop disease. Gene mutations can be generally categorized into two types: point mutations and base-pair insertions or deletions. Point mutations are the most common type of gene mutation. Also called a base-pair substitution, this type of mutation changes a single nucleotide base pair.
Point mutations are single base changes, that do not affect the reading frame; that is, the mutation only makes a single change in a single codon, and everything else is undisturbed. There are three types of point mutation:1  Silent Mutation.oint mutations are single base changes, that do not affect the reading frame; that is, the mutation only makes a single change in a single codon, and everything else is undisturbed. There are three types of point mutation: 1  Silent Mutation.