SÅAWOMIRA f Polish. Polish feminine form of SÅAWOMIR. SLOAN f English (Rare). Variant of SLOANE. SLOANE f English (Rare). From an Irish surname which was derived from an Anglicized form of the given name SLUAGHADHAN. SLUAGHADHÃ¡N slobodan M, Serbian, Macedonian. Croatian From South slavic sloboda meaning. freedomreek form of SOPHRONIUS. SOPHRONIUS m Late Greek (Latinized). Latinized form of the Greek name ÏÏÏÏÎ¿Î½Î¹Î¿Ï (Sophronios) , which was derived from Greek ÏÏÏÏÏÎ½ (sophron) self-controlled, sensible ... [more]. SOPHUS m Ancient Greek (Latinized). From the Greek name ÏÎ¿ÏÎ¿Ï (Sophos) which meant skilled, clever.
But a burgeoning field known as epigenetics is showing that many cancers may not be caused by mutations in genes, but by chemical modifications that alter how the genes function. Such modifications to genes are epigenetic-literally on top of or related to changes in the DNA sequence.
For at least a decade, the number of known associations between epigenetic changes and cancer has been growing. Abnormal methylation can be found in most cancers, and mutations in the enzymes that add methyl groups to DNA have been associated with some cancer types.In most human cancers, Shen said, the promoter of p16 contains methylated cytosine residues.pigenetic Changes Can Cause Cancer. A transgene designed to attract methylation to the promoter of a tumor-suppressor gene leads to tumorigenesis in a mouse model.