Hypokinetic movements include: 1  Bradykinesia. 2  Freezing. 3  Rigidity. 4  Postural instability.
Mutations cause changes in the genetic code that lead to genetic variation and the potential to develop disease. Gene mutations can be generally categorized into two types: point mutations and base-pair insertions or deletions. Point mutations are the most common type of gene mutation. Also called a base-pair substitution, this type of mutation changes a single nucleotide base pair.
Point mutations may be deletions or insertions of nucleotides, or changes from one nucleotide to another (substitutions). To understand the types of changes, it is useful to remember that the DNA nucleotides are adenine, thymine, cytosine, and guanine (abbreviated A, T, C, G).