Hypokinetic movements include: 1  Bradykinesia. 2  Freezing. 3  Rigidity. 4  Postural instability.
Mutations cause changes in the genetic code that lead to genetic variation and the potential to develop disease. Gene mutations can be generally categorized into two types: point mutations and base-pair insertions or deletions. Point mutations are the most common type of gene mutation. Also called a base-pair substitution, this type of mutation changes a single nucleotide base pair.
Of all the ways the genome can be changed, the simplest type of mutation is the point mutation. In a point mutation, a single base is substituted for another, changing the meaning of a single codon, leaving the rest of the gene unchanged. Geneticists recognize four types of point mutations, based on the effect on the genome.