Fatigue is the most common symptom and other symptoms include an enlarged liver, jaundice, itching skin rashes, joint pain, and abdominal pain. These symptoms range from mild to severe and can lead to cirrhosis (scarring and hardening) of the liver and may eventually lead to liver failure.
Born in Adelaide, South Australia, on 24 September 1898, Howard Florey was the youngest of five children and the only boy in his family. His father was a bootmaker and ran a successful company. At school Florey was nicknamed 'Floss', a name that stayed with him for life.
Howard Rusk Long was born in 1906 in Columbia, Missouri. His parents were C. M. Long and Carrie B. Long. He was one of their three children. Long's father was a well-known farmer in Rochester, Indiana. In 1925, the Long family moved to Lafayette, Indiana. Long graduated with a Bachelor of Journalism in 1930 from the University of Missouri.