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Until recent years, the standard treatment for a UTI was 10 days of amoxicillin, a penicillin antibiotic, but it is now ineffective against E. coli bacteria in many cases. A combination of amoxicillin-clavulanate (Augmentin) is sometimes given for drug-resistant infections.
Macrobid, Augmentin, Cipro, Amoxicillin, etc. It really depends on the type of bacteria that is present in the urinary tract. In general, Macrobid (Nitrofurantoin), is used specifically to treat UTI's. Holding your urine too long can cause you to have a UTI or urethritis.