In situations where the concomitant use of clarithromycin with statins cannot be avoided, it is recommended to prescribe the lowest registered dose of the statin. Use of a statin that is not dependent on CYP3A metabolism (e.g. fluvastatin or pravastatin) should be considered (see section 4.5).
On the basis of these data, they assumed the ancient model of and estimated both a recent epoch of exponential growth and the population size before growth, pointing to growth starting 3.5 (2.9â4.1) kya at a rate of 3.4% (2.4â5.1%) per generation, resulting at 0.65 (0.30â2.87) millions individuals today (Figure 1b and Table 2).
The Tulsa metro ranked 46th in growth among the 89 metropolitan areas in the U.S. with a population of at least 500,000. The Oklahoma City metro area grew by 1.2 percent to 1,336,767 residents during the year ending July 1, 2014. That area grew by 1.7 percent the previous year.