Several other disease processes involve both inflammation and bone uncoupling. For example, similar to periodontal disease, osteoporosis is also characterized by uncoupling due to deficient bone formation following bone resorption. list of molecules that could mediate the effects of inflammation on uncoupling is provided in Table 2. Although this review focuses on bone, it is recognized that, for periodontal regeneration to occur, the formation of new cementum and periodontal ligament must also take place (Foster et al., 2007).
Lenneberg (1967) sees the critical period starting at the age of 2 and ending around puberty, a period, which coincides with the brain lateralisation process, which is the specialisation of the dominant hemisphere of the brain language functions. Lenneberg (1967) cited a wide evidence of changes in the brain taking place during this period.
Critical Periods to Know. There are many specific physical, psychosocial (also called social/emotional or relating), and cognitive development milestones that most typically developing children go through. One of the earliest psychosocial critical periods is bonding. This happens in the newborn period. Holding, soothing, and caring for your baby makes it easy for her to move through this critical period. Another critical period involves the development of language skills. During the first two years of your childâs life it is important to provide a rich environment with regards to language.