Hypersecretion - Too much of any hormone secreted into the body is usually caused by a secretory pituitary gland tumor. Secretory tumors produce too much prolactin (the hormone that triggers milk production in new mothers), which leads to infertility, discharge from breasts and menstrual abnormality.
Roadster uses about 230Wh/mile at 55mph, we know that Model S 85kWh battery should last 300 miles at 55mph. That gives us 283Wh/mile. Difference is 53Wh. Roadster uses about 330Wh/mile at 75mph, so Model S should use 383Wh/mile at 75mph. 85kWh/383Wh/mile = 222 miles. Estimation, but should not be far from truth.
The car actually managed 423.5 miles before the duo finally stopped, ready to be towed home. There's another significance to the 400-mile record--it comfortably beats the maximum range attained in Tesla's own Roadster, when two Australian owners hit 313 miles back in 2009.