The Centers for Disease Control and Prevention (CDC) is a federal agency that conducts and supports health promotion, prevention and preparedness activities in the United States, with the goal of improving overall public health. Established in 1946 and based in Atlanta, the CDC is managed by the Department of Health and Human Services .
Definition of ale. 1  1 : an alcoholic beverage brewed especially by rapid fermentation from an infusion of malt with the addition of hops. 2  2 : an English country festival at which ale is the principal beverage.
As hops began to pervade breweries, however, this distinction between beer and ale no longer applied. Brewers began to differentiate between beer and ale on the basis of where the yeast fermented in the cask: ale uses yeast that gathers on the top, and lager uses yeast that ferments on the bottom.