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tolerance. Tolerance is the quality of requiring a larger dose of a certain drug every time to reach the same effects. For example, if you need 2-5 hits to get stoned at first, if you smoke regularly and at close intervals (every day or every other day) you will start requiring more hits to get the same high.
Tolerance. tolerance. 1. The ability to endure unusually large doses of a drug or toxin. 2. Acquired drug tolerance, a decreasing response to repeated constant doses of a drug or the need for increasing doses to maintain a constant response.Origin: L. Tolerantia.Please contribute to this project, if you have more information about this term feel free to edit this page.cquired drug tolerance, a decreasing response to repeated constant doses of a drug or the need for increasing doses to maintain a constant response.