In situations where the concomitant use of clarithromycin with statins cannot be avoided, it is recommended to prescribe the lowest registered dose of the statin. Use of a statin that is not dependent on CYP3A metabolism (e.g. fluvastatin or pravastatin) should be considered (see section 4.5).
On the basis of these data, they assumed the ancient model of and estimated both a recent epoch of exponential growth and the population size before growth, pointing to growth starting 3.5 (2.9â4.1) kya at a rate of 3.4% (2.4â5.1%) per generation, resulting at 0.65 (0.30â2.87) millions individuals today (Figure 1b and Table 2).
2000 Census Population 234,403 1,551,351 2010 Census Population 242,803 1,671,683 Population Change 2000 to 2010 8,400 120,332 Percent Population Change 2000 to 2010 3.6% 7.8% 2013 Population Estimate (Weldon Cooper Center, UVA) 246,392 1,682,842 * Source: 2000 and 2010 Census, and Weldon Cooper Center at UVA * Virginia portion of MSA Norfolk Region TOTAL POPULATION 242,803 100.0% 1,671,683 Population of one race 233,978 96.4% 1,614,302 96.6% 114,304 47.1% 997,082 59.6%