webmd symptom checker helps you find the most common medical conditions indicated by the symptoms frequent urination itching or burning pain during erection and pain with sexual intercourse male including urinary tract infection uti diabetes type 2 and liceebmd symptom checker helps you find the most common medical conditions indicated by the symptoms frequent urination itching or burning pain during erection and pain with sexual intercourse male including urinary tract infection uti diabetes type 2 and lice
FMR1 (fragile X mental retardation 1) is a human gene that codes for a protein called fragile X mental retardation protein, or FMRP.This protein, most commonly found in the brain, is essential for normal cognitive development and female reproductive function.s a result, this part of the FMR1 gene is methylated, which silences the gene (it is turned off and does not make any protein). Without adequate FMRP, severe learning deficits or mental retardation can develop, along with physical abnormalities seen in fragile X syndrome.
The PRPS1 gene provides instructions for making an enzyme called phosphoribosyl pyrophosphate synthetase 1, or PRPP synthetase 1. This enzyme helps produce a molecule called phosphoribosyl pyrophosphate (PRPP).PRPP is involved in making purine and pyrimidine nucleotides.n a milder form of PRS superactivity, the PRPS1 gene is overactive for reasons that are not well understood. PRPS1 gene overactivity increases the production of normal PRPP synthetase 1 enzyme, which increases the availability of PRPP. In both forms of the disorder, excessive amounts of purines are generated.