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FMR1 (fragile X mental retardation 1) is a human gene that codes for a protein called fragile X mental retardation protein, or FMRP.This protein, most commonly found in the brain, is essential for normal cognitive development and female reproductive function.s a result, this part of the FMR1 gene is methylated, which silences the gene (it is turned off and does not make any protein). Without adequate FMRP, severe learning deficits or mental retardation can develop, along with physical abnormalities seen in fragile X syndrome.
FMR1 (Fragile X Mental Retardation 1) is a Protein Coding gene. Diseases associated with FMR1 include fragile x tremor/ataxia syndrome and premature ovarian failure 1. Among its related pathways are Translational Control and Neuroscience.GO annotations related to this gene include RNA binding and mRNA binding.he protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm.