Causes of Ankle Pain. 1  Ankylosing Spondylitis Ankylosing spondylitis is a type of arthritis that causes chronic inflammation of the spine. 2  Arthritis Arthritis is inflammation of one or more joints. 3  Broken Bone (Types of Bone Fractures) A broken bone is a fracture.
Down syndrome is a chromosomal condition that is associated with intellectual disability, a characteristic facial appearance, and weak muscle tone (hypotonia) in infancy. All affected individuals experience cognitive delays, but the intellectual disability is usually mild to moderate.
Down syndrome is a condition in which there are three copies of chromosome 21 within the cells of the body instead of two. The extra chromosomes result in delayed physical development and mental retardation. There are three types of Down syndrome: Trisomy 21, Translocation, and Mosaic Down syndrome.