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It is metabolized in the liver and excreted into the bile ducts. It becomes a component of bile, a fluid that is secreted into the intestines to aid in food digestion. Bilirubin is a yellow pigment that causes jaundice and dark yellow colored urine when present in increased amounts. Some people normally have higher bilirubin in their blood.
Sickle cell anemia â a chronic shortage of red blood cells â can be the cause of blood in urine, both gross and microscopic hematuria. So can Alport syndrome, which affects the filtering membranes in the glomeruli of the kidneys. Kidney injury. A blow or other injury to your kidneys from an accident or contact sports can cause blood in your urine that you can see. Medications.