Hypokinetic movements include: 1  Bradykinesia. 2  Freezing. 3  Rigidity. 4  Postural instability.
Mutations cause changes in the genetic code that lead to genetic variation and the potential to develop disease. Gene mutations can be generally categorized into two types: point mutations and base-pair insertions or deletions. Point mutations are the most common type of gene mutation. Also called a base-pair substitution, this type of mutation changes a single nucleotide base pair.
Genes can become mutated for various reasons, and mutations can occur in several different ways. The simplest type of mutation is a substitution of a different DNA base. For example, thymine (T) may replace adenine (A), which could change the message of the gene.