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A liver metastasis is a malignant tumor in the liver that has spread from another organ affected by cancer. The liver is a common site for metastatic disease because of its rich, dual blood supply (the liver receives blood via the hepatic artery and portal vein). Metastatic tumors in the liver are 20 times more common than primary tumors. In 50% of all cases the primary tumor is of the gastrointestinal tract, other common sites include the breast, ovaries, bronchus and kidney.
Bone metastasis happens in people who have cancer that forms in another part of the body. Cancer cells from that area break away and travel through the bloodstream and lymphatic system. When the cancer spreads to distant body organs, this is called metastasis. bone metastasis can grow in any bone. But cancer most commonly spreads to the bones that are close to the center of the body. The spine is the most common place for a bone metastasis to form. Other common areas for bone metastases include the thigh bone, upper arm bone, ribs, hips, and skull.