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A pancreaticoduodenectomy, pancreatoduodenectomy, Whipple procedure, or Kausch-Whipple procedure, is a major surgical operation involving the removal of the head of the pancreas, the duodenum, the proximal jejunum, gallbladder, and part of the stomach.
The Whipple operation was first described in the 1930âs by Allan Whipple. In the 1960âs and 1970âs the mortality rate for the Whipple operation was very high. Up to 25% of patients died from the surgery. This experience of the 1970âs is still remembered by some physicians who are reluctant to recommend the Whipple operation.