After a long, hard day of hunting and gathering, our ancestors would huddle together for safety, such as it was, to endure another night of uneasy sleep, always mindful of the hungry beasts out there â¦ perhaps close by â¦ that they could not see.
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Iron cannot be transported around the body's circulation system as free iron, since it would be susceptible to chelation by siderophores, or may precipitate as iron(III) oxide, or may form iron(II). Therefore, a specific transport protein is required, called transferrin. (In fact, a whole class of transferrin-like proteins is involved in iron transport.) Transferrin is a medium-sized protein with a relative molecular mass of about 80 000.