My feet & ankles are swollen, hot and reddish color. I have high blood pressure, lupus, asthma, back problems, diabetic, fibromyalgia, and Padgett disease, an enlarged heart, and enlarged thymus gland.
1 Free T4 (Free Thyroxine) â considered a precursor hormone, T4 is converted to T3 as required by cells throughout the body; levels of T4 are generally much higher than T3.  Total T4 (Total Thyroxine) - Most T4 in the blood is bound to carrier proteins which make it biologically inactive. Total T4 includes unbound (free) T4 plus T4 that is bound to carrier proteins in the blood.
Atrial natriuretic peptide (ANP), a hormone secreted by the atria of the heart, lowers blood pressure by causing vasodilation and by stimulating the kidneys to excrete more water and Na +(lowering blood pressure by reducing blood volume). Nitric oxide (NO), secreted by endothelial cells, causes vasodilation.