Europe and later Africa exported, unintentionally, more than a dozen diseases that killed large numbers of American natives. Some, like measles and chickenpox, were childhood diseases that usually did not cause many deaths in the Old World but killed millions of American natives.
Mission Bay (San Diego) Mission Bay is a saltwater bay or lagoon located south of the Pacific Beach community of San Diego, California. The bay is part of the recreational Mission Bay Park, the largest man-made aquatic park in the country, consisting of 4,235 acres (17.14 km2), approximately 46% land and 54% water. The combined area makes Mission Bay Park the ninth largest municipally-owned park in the United States.
From Highway 35, turn west onto Alpine Road, go 3 miles, and turn onto Portola State Park Road. The road dead ends in the park. Use low gear as both these roads are steep and winding. Due to mountain roads, expect a 1 1/2 to 2 hour drive from most Bay Area locations. There is no gasoline available at or near the park.