DST isoform 6 is required for bundling actin filaments around the nucleus. DST isoform 7 regulates the organisation and stability of the microtubule network of sensory neurons to allow axonal transport. Molecular pathology. Defects of DST cause hereditary sensory and autonomic neuropathy type 6.
Long Time Survivor. Not only does the virus survive in adverse climate conditions, it's also quite long living. According to Utah Veterinary Clinics, parvo can live in the environment for six months to one year. The time frame seems to depend on several factors.
First, a puppy's immune system needs time to accommodate the necessary vaccinations. Depending on the disease profile of your area, that could mean it's not safe to walk him until he's about 16 weeks old. (That was the case here, where parvo is occasionally introduced from a town about an hour south.)