DST isoform 6 is required for bundling actin filaments around the nucleus. DST isoform 7 regulates the organisation and stability of the microtubule network of sensory neurons to allow axonal transport. Molecular pathology. Defects of DST cause hereditary sensory and autonomic neuropathy type 6.
Long Time Survivor. Not only does the virus survive in adverse climate conditions, it's also quite long living. According to Utah Veterinary Clinics, parvo can live in the environment for six months to one year. The time frame seems to depend on several factors.
Parvo Symptoms. Symptoms include depression, usually a fever of 104 to 106 degrees, refusal to eat or drink, and severe vomiting along with diarrhea. Vomiting is often the first sign, with diarrhea usually appearing within 24 to 48 hours.