Soccer Positions. According to the rules of soccer, there are only two types of players, the goalkeeper and everyone else. However, in actual play, different players will need to have different skills and play different roles or positions. Below we will discuss some of those roles.
In some lung cancer patients this gene, called EGFR, contains a DNA change known as an inherited EGFR mutation. Early data indicate that these inherited EGFR mutations may be associated with an increased risk of lung cancer. So far, only a small number of families have been found to carry inherited EGFR mutations. For this reason the risk of lung cancer associated with inherited EGFR mutations is not well understood.
2004). However, EGFR mutations can also be found in other subsets of NSCLC, including in former and current smokers as well as in other histologies. In the vast majority of cases, EGFR mutations are non-overlapping with other oncogenic mutations found in NSCLC (e.g., KRAS mutations, ALK rearrangements, etc.). Figure 1. Schematic of EGFR mutations. Exons 18â21 of the EGFR kinase domain are depicted.