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Description. This medicine, Trazodone (Desyrel), is a modified cyclic antidepressant. Trazodone belongs to the group of medicines known as antidepressants or mood elevators.. It is used to treat mental depression and depression that sometimes occurs with anxiety.
Here are the main considerations for using drug trazodone to treat insomnia: 1  Insomnia without depression. Because there's so little supporting evidence, sleep experts generally recommend trazodone for insomnia only after the newer sleep drugs have failed. 2  Insomnia with depression.