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In general, antibody tests that use blood can detect HIV slightly sooner after infection than tests done with oral fluid. It can take 3 to 12 weeks (21-84 days) for an HIV-positive personâs body to make enough antibodies for an antibody test to detect HIV infection. This is called the window period.
Antibody/antigen tests. These tests are recommended by the CDC and can detect HIV up to 20 days earlier than standard tests. They check for HIV antigen, a part of the virus that shows up 2-4 weeks after infection.These tests can also detect HIV antibodies.ntibody/antigen tests. These tests are recommended by the CDC and can detect HIV up to 20 days earlier than standard tests. They check for HIV antigen, a part of the virus that shows up 2-4 weeks after infection.