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Within eukaryotes, DNA replication is controlled within the context of the cell cycle. As the cell grows and divides, it progresses through stages in the cell cycle; DNA replication takes place during the S phase (synthesis phase).
Origin of replication is formed of about 100-200 or more nucleotides. 4. Replication of DNA occurs at one point in each prokaryotic DNA molecule. 5. Only two replication fork is formed in each replicating prokaryotic chromosome, as DNA replication is bidirectional.