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Bactrim is a sulfa-based antibiotic and is not a penicillin-based medicine, according to RxList. However, a patient should discuss all allergies with a doctor to determine what drugs can and cannot be taken. Continue Reading.
Another name for this class is the beta-lactam antibiotics, referring to their structural formula. 1  The penicillin class contains five groups of antibiotics: aminopenicillins, antipseudomonal penicillins, beta-lactamase inhibitors, natural penicillins, and the penicillinase resistant penicillins. Common antibiotics in the penicillin class include: penicillin V potassium; amoxicillin; amoxicillin/clavulanate (Augmentin) View penicillin drugs. 2.