The Gothic Revival style is part of the mid-19th century picturesque and romantic movement in architecture, reflecting the public's taste for buildings inspired by medieval design. This was a real departure from the previously popular styles that drew inspiration from the classical forms of ancient Greece and Rome.
What is the lethal dose of caffeine in humans? http://www.consumergenetics.com/caffeine_test.php. The lethal dose of caffeine is 2 grams of caffeine per day, that is, 80-100 cups of coffee a day. For slow metabolizers of caffeine, the lethal dose of caffeine can be lower.
There are a number of toxic substances, and their toxicity spans a tremendous range. As Quora User mentioned, plutonium is way up there, but it is not the most toxic. Sodium cyanide is reported to be fatal at a dose of 1.5 milligrams per kilogram of body weight. So for an 80 kg person that would be about 120 mg.