Best Answer: The biggest reason was that Britain started the Industrial Revolution earlier than other countries. Because they had newer technology, they could sell it to other countries to make money, and also use it to conquer other places.
1 Atopic dermatitis (AD) with Filaggrin (FLG) mutations is associated with an increased SC IL-1 cytokine profile; this profile is also seen in a murine homologue of filaggrin deficiency. 2  FLG mutations increase the risk for persistent dry skin, persistent eczema, and AE and non-AE at age 8 years. Loss-of-function mutations in the gene encoding FLG are linked with IV in Northern European and Japanese populations and results here demonstrate that FLG mutations are also associated with IV in a Bangladeshi population.
TEXT. A number sign (#) is used with this entry because postaxial polydactyly type A1 (PAPA1) and type B (PAPB) can be caused by heterozygous mutation in the GLI3 (165240) gene on chromosome 7p. See also preaxial polydactyly type IV (174700), an allelic disorder.Description.n a patient with postaxial polydactyly type B of the hands, Furniss et al. (2007) identified a heterozygous mutation in the GLI3 gene (165240.0015), which was predicted to result in premature termination and shown to be subject to nonsense-mediated mRNA decay.