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Manufacturers universally tell you to refrigerate mayonnaise once opened, though, because it helps preserve the flavor. Warmth causes mayonnaise to break down after a while, and it gets to the point where it just tastes oily. Homemade mayonnaise, of course, is a different matter. With its use of raw eggs, it is highly perishable and should be consumed immediately or refrigerated and finished off very shortly.
Sep 16, 2013 12:06 PM By Lizette Borreli @lizcelineb. The age-old debate of whether eggs need to be refrigerated or stored at room temperature has been cracked by British scientists.StaraBlazkova, CC BY-SA 3.0.ecause of these immunization policies and practicies, it is imperative to keep eggs refrigerated.To minimize the risk of contamination and to extend shelf life, eggs should be stored in the case or carton in a refirgerator.