Find possible causes of numbness or tingling in hands based on specific factors. Check one or more factors on this page that apply to your symptom. Numbness or tingling. 1  Affects both hands. 2  Affects one hand.  Is intermittent.
These cells produce melanin, the substance that gives skin its color. Skin with too much melanin is called hyperpigmented skin. Skin with too little melanin is called hypopigmented skin. Pale skin areas are due to too little melanin or underactive melanocytes. Darker areas of skin (or an area that tans more easily) occurs when you have more melanin or overactive melanocytes. Bronzing of the skin may sometimes be mistaken for a suntan.
When the pigment-forming cells (melanocytes) are destroyed, it results in loss of pigment in the skin. Medical experts have linked this to the autoimmune condition â a condition where the immune system mistakenly destroys its own cells instead of foreign substances such as bacterial and viral agents.t occurs when melanocytes, the cells responsible for skin pigmentation, are damaged or destroyed by the autoimmune attack. Vitiligo tends to appear in symmetric patches sometimes covering large areas of the body.