The application is compatible with the Graphics Interchange Format, but with some limitations. When you post GIF files on Instagram the animation is lost, so the image might not display as expected.he application is compatible with the Graphics Interchange Format, but with some limitations. When you post GIF files on Instagram the animation is lost, so the image might not display as expected.
Advisory about methemoglobinemia with the use of benzocaine sprays durÂ­ ing medical procedures. Since then, FDA has received reports of 72 new cases of methemoglobinemia associated with the use of benzocaine sprays, including 3 resulting in death, bringing the total to 319 cases as of March 16, 2011. Of the 319 cases, 7 were deaths, 32 cases were categorized as life threatening, and 216 were categorized as serious. A review of the 319 cases indicated that the development of methemoglobinÂ­ emia after treatment with benzocaine sprays may not be related to the amount applied. In many cases, methemoglobinÂ­ emia was reported following the adminÂ­ istration of a single benzocaine spray. In other cases, methemoglobinemia resulted after excessive amounts were applied.
Methemoglobinemia is a condition in which more than 1% of the hemoglobin in red blood cells takes the form of methemoglobin. Methemoglobulin is an abnormal form of hemoglobin (the molecule responsible for carrying oxygen in the blood cells) that is unable to bind to oxygen.utations in the HBB gene cause methemoglobinemia, beta-globin type. Hemoglobin consists of four protein subunits and four iron-containing molecules called heme. Heme molecules are necessary for red blood cells to pick up oxygen in the lungs and release oxygen to other cells in the body.