Stop using bosutinib and call your doctor at once if you have: 1  severe or ongoing nausea, vomiting, stomach pain, or diarrhea; 2  black, bloody, or tarry stools, coughing up blood or vomit that looks like coffee grounds;  fever, chills, body aches, flu symptoms, sores in your mouth and throat;
Certain breeds, such as Labradors and others with long, hanging ears, are more at risk of getting ear infections. Other dogs, like poodles, have a lot of hair in their ear canals that puts them at risk for infections when wax and dirt become trapped within the hair. Any breed of dog that has a type of allergic skin disease can suffer with chronic ear infections as well.
Rickettsial diseases, caused by organisms in the genera Ehrlichia and Anaplasma, cause mild to severe loss of platelets in dogs. Infection may include short- and longterm changes in the number of platelets and other blood cells. Ticks are the usual carriers of the infection. Infected dogs may have nosebleeds, bleeding into the bowels (resulting in black stools), bleeding of the gums, and prolonged bleeding after vaccination or surgery.