In the simplest of terms, a drug's volume of distribution is that volume of bodily fluid into which a drug dose is dissolved. Therefore, if we know the dose that was given, and we can measure the serum level (concentration), then we can calculate a volume: Volume of distribution = Dose / drug concentration.
As soon as you can make the reservation, do it, but the general consensus is at least three to six months in advance of the date. By three months out, couples have a good idea how many guests will be attending and they can plan a menu that doesnât conflict with their wedding day.
Answer: Generally you donât want to arrive any more than 30 minutes prior to the curtain or any less than 10 minutes prior. The house wonât open until 30 minutes before, and there is no need to line up prior to that as your seat is assigned! If you are picking up tickets at the box office, want to get a cocktail, or need to use the restroom before showtime, about 20-25 minutes prior to curtain is advisable.