A fibroblast is a type of cell that synthesizes the extracellular matrix and collagen,[1] the structural framework (stroma) for animal tissues, and plays a critical role in wound healing. Fibroblasts are the most common cells of connective tissue in animals.
For example, a 700 x 20 C road tire would be a 20-622; a 700 x 38 hybrid tire would be a 38-622. The width difference between these sizes would make them less-than ideal replacements for one another, but any rim that could fit one of them would work after a fashion with the other.
Rim/Wheel Widths. Each tire has a specific rim width range on which the tire can be mounted. Failure to follow rim width recommendations may result in poor tire performance or possible wheel and/or tire failure. Below is a quick reference chart listing each tire size and the acceptable rim widths for that size. (The chart does not show all sizes, but gives a good example) Choosing a wheel near the middle of the range will give a balance between ride quality and handling. A wider wheel will improve handling at the expense of ride quality, while a narrower wheel will improve ride quality at the expense of handling.