A History of Excellence. GFOA has awarded the City of Wilmington a Certificate of Achievement for Excellence in Financial Reporting for its comprehensive annual financial report, consecutively, since 1984.
Glycine encephalopathy is sometimes referred to as nonketotic hyperglycinemia (NKH), as a reference to the biochemical findings seen in patients with the disorder, and to distinguish it from the disorders that cause ketotic hyperglycinemia (seen in propionic acidemia and several other inherited metabolic disorders).lycine encephalopathy has an estimated incidence of 1 in 60,000, making it the second most common disorder of amino acid metabolism, after phenylketonuria. It is caused by a defect in the glycine cleavage system (GCS), which is made up of four protein subunits.
Glycine is a neurotransmitter only in vertebrate animals. The glycine receptor is primarily found in the ventral spinal cord. Strychnine is a glycine antagonist which can bind to the glycine receptor without opening the chloride ion-channel (ie, it inhibits inhibition).