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After treatment, a small number of people still have some symptoms, such as muscle aches and fatigue. The cause of these continuing symptoms, known as post-treatment Lyme disease syndrome, is unknown, and treating with more antibiotics doesn't help.Some experts believe that certain people who get Lyme disease are predisposed to develop an autoimmune response that contributes to their symptoms.More research is needed.he cause of these continuing symptoms, known as post-treatment Lyme disease syndrome, is unknown, and treating with more antibiotics doesn't help. Some experts believe that certain people who get Lyme disease are predisposed to develop an autoimmune response that contributes to their symptoms. More research is needed.
People treated with antibiotics in the early stages of a Lyme disease infection usually recover rapidly and completely. Antibiotic treatment can range from 14 to 28 days. A few people, particularly those who are first diagnosed with later stages of the disease, may have persistent or recurrent symptoms.