Find possible causes of numbness or tingling in hands based on specific factors. Check one or more factors on this page that apply to your symptom. Numbness or tingling. 1  Affects both hands. 2  Affects one hand.  Is intermittent.
These cells produce melanin, the substance that gives skin its color. Skin with too much melanin is called hyperpigmented skin. Skin with too little melanin is called hypopigmented skin. Pale skin areas are due to too little melanin or underactive melanocytes. Darker areas of skin (or an area that tans more easily) occurs when you have more melanin or overactive melanocytes. Bronzing of the skin may sometimes be mistaken for a suntan.
Vitiligo (vit-ill-EYE-go) is a disorder in which white patches of skin appear on different parts of the body. This happens because the cells that make pigment (color) in the skin are destroyed.These cells are called melanocytes (ma-LAN-o-sites).n vitiligo, the immune system may destroy the melanocytes in the skin. It is also possible that one or more genes may make a person more likely to get the disorder. Some researchers think that the melanocytes destroy themselves. Others think that a single event such as sunburn or emotional distress can cause vitiligo.