Infection with malaria parasites may result in a wide variety of symptoms, ranging from absent or very mild symptoms to severe disease and even death. Malaria disease can be categorized as uncomplicated or severe (complicated) .
The most well-studied antidepressants for fibromyalgia include duloxetine (Cymbalta), milnacipran ( Savella), and venlafaxine (Effexor). Cymbalta and Savella are specifically FDA-approved to treat fibromyalgia. There is less medical research to show that Effexor helps fibromyalgia.
In June 2007, Lyrica (pregabalin) became the first FDA-approved drug for specifically treating fibromyalgia; a year later, in June 2008, Cymbalta (duloxetine hydrochloride) became the second; and in January 2009, Savella (milnacipran HCI) became the third.