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According to my doctor, 4 hours. You can switch them up. Take acetaminophen, (Tylenol), then wait 4 hours and take Ibuprofen, wait another 4 hours and take acetaminophen and so on. :) 15 people found this useful.
Acetaminophen is tylenol and the body can take no more than two.... Acetaminophen is Tylenol and the body can take no more than two at one time every 4 hours assuming you don`t have a 12 hour time release pill. In that case, just take one every 12 hours. Any more at one time and you will damage your organs.