Best Answer: The biggest reason was that Britain started the Industrial Revolution earlier than other countries. Because they had newer technology, they could sell it to other countries to make money, and also use it to conquer other places.
1 Atopic dermatitis (AD) with Filaggrin (FLG) mutations is associated with an increased SC IL-1 cytokine profile; this profile is also seen in a murine homologue of filaggrin deficiency. 2  FLG mutations increase the risk for persistent dry skin, persistent eczema, and AE and non-AE at age 8 years. Loss-of-function mutations in the gene encoding FLG are linked with IV in Northern European and Japanese populations and results here demonstrate that FLG mutations are also associated with IV in a Bangladeshi population.
In contrast to tumors from patients with VHL germline mutation, however, point mutations of the wild-type allele can be detected in tumors from patients with VHL germline deletion.Oncogene (2002) 21, 1167 - 1170 DOI: 10.1038/sj/onc/1205121.ll three tumors showed retention of one VHL allele by FISH. Single-strand conformation polymorphism and mutation analysis of microdissected tumor DNA revealed somatic point mutations of the wild-type VHL copies in each of the three tumors.