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Cavity Structural Effect. The Cavity Structural Effect (CSE) was discovered in spring 1983 by chance by Viktor S. Grebennikov (1927-2001), entomologist and painter, when he moved his hand over multi cavernous bee nests and felt warmth emanating from them.
The size of the malformation. Cavernous malformations can range in size from less than a quarter of an inch to the size of a tangerine. The larger the malformation is the more likely it is to cause problems for the patient. Whether the malformation shows signs of bleeding. Bleeding may cause arteriovenous malformations,symptoms similar to those of a stroke. It also causes a cavernous malformation to get larger. The blood itself can irritate the tissues of the brain and cause seizures.