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endocrine signaling. Signaling in which endocrine cells release hormones that act on distant target cells.
The Hedgehog Signaling Pathway in Vertebrates. The hedgehog signaling pathway is a mechanism that regulates cell growth and differentiation during embryonic development, called embryogenesis, in animals. The hedgehog signaling pathway works both between cells and within individual cells. The hedgehog gene (hh) was observed in fruit flies (Drosophila melanogaster) in 1980, and later in vertebrates in 1993. Unlike flies, which have one hh gene, vertebrates have several hh genes.