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Heightened sense of smell. Hello. My wife has a condition called hyperosmia, which, as I'm sure you know, is an elevated sense of smell. Not only does she smell odors that no one else even notices, the odors are always nauseating to her.
Why regular smells make some people sick. People who feel sick when they smell and overpowering perfume may not necessarily be allergic, but may have a condition that results in the inability to get used to smells. Usually your smell perceptions diminish rapidly, for example when you walk into someone else's house or get into a new car you notice a different smell immediately. After a while, most people stop noticing them. However, some people have a chemical intolerance which means that the smells continue to be present.