The Japanese word for Japan is æ¥æ¬, which is pronounced Nippon or Nihon and literally means the origin of the sun. The earliest record of the name Nihon appears in the Chinese historical records of the Tang dynasty, the Old Book of Tang.
The secondary immune response occurs the second time (3rd, 4th, etc.) the person is exposed to the same antigen. At this point immunological memory has been established and the immune system can start making antibodies immediately.
The immune response When a foreign substance enters the body for the first time, symptoms of disease may appear while the immune system is making antibodies to fight it. Subsequent attacks by the same antigen stimulate the immune memory to immediately produce large amounts of the antibody originally created.