Define statement: something stated: such as; a single declaration or remark : assertion; a report of facts or opinions â statement in a sentence
Within eukaryotes, DNA replication is controlled within the context of the cell cycle. As the cell grows and divides, it progresses through stages in the cell cycle; DNA replication takes place during the S phase (synthesis phase).
The problem of how DNA replication occurs only once in each cell cycle has been partially resolved by studies in the fission yeast, Schizosaccharomyces pombe, where genetic approaches have been used to study the sequential coupling of the S and M phases. As will be discussed, Cdk are implicated as central regulators.