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Within eukaryotes, DNA replication is controlled within the context of the cell cycle. As the cell grows and divides, it progresses through stages in the cell cycle; DNA replication takes place during the S phase (synthesis phase).
In a cell, DNA replication begins at specific locations in the genome, called origins . Unwinding of DNA at the origin, and synthesis of new strands, forms a replication fork.n a cell, DNA replication begins at specific locations in the genome, called origins . Unwinding of DNA at the origin, and synthesis of new strands, forms a replication fork.