A fibroblast is a type of cell that synthesizes the extracellular matrix and collagen,[1] the structural framework (stroma) for animal tissues, and plays a critical role in wound healing. Fibroblasts are the most common cells of connective tissue in animals.
For example, a 700 x 20 C road tire would be a 20-622; a 700 x 38 hybrid tire would be a 38-622. The width difference between these sizes would make them less-than ideal replacements for one another, but any rim that could fit one of them would work after a fashion with the other.
The tire size was designed to fit rims or wheels that are 17 inches in diameter. 100. This tire has a load index of 100, which means it's capable of carrying a load of 1760 pounds (800 kg) or less. A higher number means the tire can carry more weight. A lower number means the opposite.