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1 Unexplained bone fractures or deformities. 2  Painful spasms or cramps in the face, hands and feet due to low levels of calcium in the blood (rare) 3  In rickets: bowed limbs (especially the legs), pot belly, waddling gait, disturbed growth.  Abnormal heart rhythms.
Adult Tay-Sachs is the mildest form. Symptoms appear during adolescence or adulthood. People with the adult form of Tay-Sachs disease usually have these symptoms: muscle weakness; slurred speech; unsteady gait; memory problems; tremors; The severity of symptoms and life expectancy varies.