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According to my doctor, 4 hours. You can switch them up. Take acetaminophen, (Tylenol), then wait 4 hours and take Ibuprofen, wait another 4 hours and take acetaminophen and so on. :) 15 people found this useful.
Usage Guidelines. Take the ibuprofen immediately after breastfeeding, so that your body has plenty of time to absorb it before your baby needs to eat again. Preferably, take it just before your baby's nap or bedtime. Follow the directions on the ibuprofen bottle box or information insert.sage Guidelines. Take the ibuprofen immediately after breastfeeding, so that your body has plenty of time to absorb it before your baby needs to eat again. Preferably, take it just before your baby's nap or bedtime. Follow the directions on the ibuprofen bottle box or information insert.