Speech Difficulties in Down Syndrome. Down syndrome (DS) is an incurable genetic disorder that has a profound impact upon a personâs physical, mental, and social development. Children with DS have anatomical and physiological differences in the mouth and throat region that affect feeding, swallowing, and oral motor skills.
1 A gross refers to a group of 144 items (a dozen dozen or a square dozen).  A great gross refers to a group of 1728 items (a dozen gross or a cubic dozen).
What is gross margin? Gross margin is the difference between 1) the cost to produce or purchase an item, and 2) its selling price. For example, if a company's manufacturing cost of a product is $28 and the product is sold for $40, the product's gross margin is $12 ($40 minus $28), or 30% of the selling price ($12/$40). Similarly, if a retailer has net sales of $40,000 and its cost of goods sold was $24,000, the gross margin is $16,000 or 40% of net sales ($16,000/$40,000).