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BMS-955176 is a maturation inhibitorâthe drug prevents HIV from producing complex âpolyproteinsâ that are cut up by protease enzymes and assembled into new virus particles. If approved, BMS-955176 would be the first HIV medication to work by preventing virus assembly, maturation, and release from infected cells.
Inhibiting Viral Entry/Exit. The next class of antiviral drugs we're going to cover is drugs that inhibit viruses from getting into and out of host cells. Clearly, this is a very important step in viral reproduction, since, like I said before, viruses must be inside host cells in order to replicate themselves.