Find possible causes of numbness or tingling in hands based on specific factors. Check one or more factors on this page that apply to your symptom. Numbness or tingling. 1  Affects both hands. 2  Affects one hand.  Is intermittent.
These cells produce melanin, the substance that gives skin its color. Skin with too much melanin is called hyperpigmented skin. Skin with too little melanin is called hypopigmented skin. Pale skin areas are due to too little melanin or underactive melanocytes. Darker areas of skin (or an area that tans more easily) occurs when you have more melanin or overactive melanocytes. Bronzing of the skin may sometimes be mistaken for a suntan.
In PV, too many red blood cells are produced, but sometimes it can also result in too many white blood cells or too many platelets (the component of blood that aids in clotting).A considerable amount of research is currently investigating PV and its treatment.Exactly why PV develops is still unclear.olycythemia vera (PV) is a blood disorder in which the body makes too many red blood cells. It's one in a family of diseases called myeloproliferative disorders.