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Bactrim is a sulfa-based antibiotic and is not a penicillin-based medicine, according to RxList. However, a patient should discuss all allergies with a doctor to determine what drugs can and cannot be taken. Continue Reading.
Â· just now. Report Abuse. Bactrim (sulfamethoxazole/trimethoprim) is a type of prescription antibiotic used to treat several infections, including urinary tract infections (UTIs). Bactrim works to treat infections such as these by interfering with the ability of bacteria to grow and multiply.