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Genetic variation is stored in a population's gene poolâthe combined alleles of all of the individuals in a population. allele frequency An allele frequency is a measure of how common a certain allele is in the population.
There are three primary sources of genetic variation, which we will learn more about: 1  Mutations are changes in the DNA. 2  A single mutation can have a large effect, but in many cases, evolutionary change is based on the accumulation of many mutations. A single mutation can have a large effect, but in many cases, evolutionary change is based on the accumulation of many mutations. 2  Gene flow is any movement of genes from one population to another and is an important source of genetic variation. 3  Sex can introduce new gene combinations into a population.