Plan you week with the help of our 10-day weather forecasts and weekend weather predictions for Estes Park, CO
BMS-955176 is a maturation inhibitorâthe drug prevents HIV from producing complex âpolyproteinsâ that are cut up by protease enzymes and assembled into new virus particles. If approved, BMS-955176 would be the first HIV medication to work by preventing virus assembly, maturation, and release from infected cells.
The HIV viral particle, or virion, has a capsid which is cone-shaped and is enclosed in a lipid bilayer, or envelope. This envelope contains viral glycoproteins which bind specifically to CD4 T cell receptors, enabling the virus to enter its host.