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endocrine signaling. Signaling in which endocrine cells release hormones that act on distant target cells.
1 An example of a hormone mediated cell signalling pathway is in the use of Insulin to lower blood glucose levels.2  In response to high glucose levels, Beta-Cells in the pancreas release the hormone Insulin in to the blood, which binds to cells such as muscle and liver cells. The signalling molecule binds to the Repeptor because its shape is complementary. 2  This then instigates a chain of reaction withing the cell, leading to a response. 3  Cell Signalling Pathways can be categorised based the distance over which the signalling occurs.