Speech Difficulties in Down Syndrome. Down syndrome (DS) is an incurable genetic disorder that has a profound impact upon a personâs physical, mental, and social development. Children with DS have anatomical and physiological differences in the mouth and throat region that affect feeding, swallowing, and oral motor skills.
1 A gross refers to a group of 144 items (a dozen dozen or a square dozen).  A great gross refers to a group of 1728 items (a dozen gross or a cubic dozen).
* In millions. Total Gross is the calendar gross for that year, meaning actual revenues during the time period, including holdovers from previous year. For a full discussion of calendar grosses, see our page: About Box Office Tracking. ^ Production cost only.