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According to my doctor, 4 hours. You can switch them up. Take acetaminophen, (Tylenol), then wait 4 hours and take Ibuprofen, wait another 4 hours and take acetaminophen and so on. :) 15 people found this useful.
For instance, one pill of Extra Strength Tylenol contains 500 mg of acetaminophen. One dose is two pills, upping the intake of acetaminophen to 1,000 mg per serving. The warning label says a person can safely take 2 caplets every 6 hours and no more than 6 in 24 hours â that is 3,000 mg.