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According to my doctor, 4 hours. You can switch them up. Take acetaminophen, (Tylenol), then wait 4 hours and take Ibuprofen, wait another 4 hours and take acetaminophen and so on. :) 15 people found this useful.
â¢ You may have cramps and heavy periods. Ibuprofen can help. You can take up to 4 pills. (800 mg) of Ibuprofen every 8 hours with food. To prevent cramps, take Ibuprofen when your. period starts and keep taking it every 8 hours for the first 2-3 days of your period.