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Keratosis pilaris results from the buildup of keratin â a hard protein that protects skin from harmful substances and infection. The keratin forms a scaly plug that blocks the opening of the hair follicle. Usually many plugs form, causing patches of rough, bumpy skin. No one knows exactly why keratin builds up. But it may occur in association with genetic diseases or with other skin conditions, such as atopic dermatitis.
Causes of Hyperkeratosis. Hyperkeratosis is a type of keratosis. Keratosis is a skin disorder that caused by overproduction of keratin. is associated with qualitative abnormality of the keratin causing thickening of the stratum corneum the horny layer of the skin. Thickening of this horny layer causes the granular layer to thicken too. This is normally due to constant friction, rubbing together and applied pressure. This leads to hardening of the skin.