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Pork loin should be cooked for approximately 30 minutes per pound in an oven that has been preheated to 350 degrees. A good way to ensure that a pork loin is properly cooked is to use a meat thermometer. The meat will be done when the thermometer reaches a temperature of 155 to 165 degrees. Continue Reading.
How do you cook pork tenderloin in the oven? To cook pan-roasted pork tenderloin in the oven, preheat the oven to 425 degrees. Cover an oven-safe skillet with oil, and brown the tenderloin over medium-high heat. Put it in the oven for 15 to 20 minutes until it is 145 degrees Fahrenheit internally.