This formula is not exact: It assumes the current density is totally uniform in the conductor, which is not always true in practical situations. However, this formula still provides a good approximation for long thin conductors such as wires.
Deferasirox is used in the treatment of transfusional iron overload in people with thalassemia. Chelation therapy is used as a treatment for metal poisoning, including acute mercury, iron (including in cases of thalassemia), arsenic, lead, uranium, plutonium and other forms of toxic metal poisoning.
However, it should be utilized if co-ingestants are suspected. In acute or chronic iron toxicity, chelation therapy with deferoxamine is indicated for patients with serum iron levels >350 mcg/dL who have evidence of toxicity, or levels of >500 mcg/dL regardless of signs or symptoms (see Medication).