The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials. The search textbox has an autosuggest feature.
Aldactone Description: Aldactone (spironolactone) is an antagonist of aldosterone and is pharmaceutically classified as a diuretic. It acts by competitively inhibiting aldosterone binding to receptor sites, especially in the renal tubes where aldosterone is involved in sodium-potassium exchange.
Q & A. Spironolactone is a potassium sparing diuretic used in the treatment of congestive heart failure (CHF), edema and high blood pressure (hypertension). Spironolactone is also used to treat potassium deficiency and hyperaldosteronism. Spironolactone requires a prescription from your veterinarian.pironolactone is a potassium sparing diuretic used in the treatment of congestive heart failure (CHF), edema and high blood pressure (hypertension).