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Sciatica results when your sciatic nerve gets pinched in your lower back. The pain is typically felt as originating in your buttock, radiating down your thigh. Stretching exercises can help reduce sciatic pain. Your sciatic nerve runs through your piriformis, a muscle located deep in your glutes.
Report Abuse. Directly, when the pinched nerve in the spine connects with nerve endings behind the knee. Indirectly, when the general effects of sciatica change the way you stand and walk. Your posture and stride change and that can cause pain in the knee. A good stretching regimen can help reduce the stress on the lower back and pressure on the sciatic nerve, along with heat and anti-inflammatories like Advil or Motrin. Source(s): Dealing with sciatica off and on for years.