1 Cold sores later crust over with a scab and are usually associated with tingling, tenderness, or burning before the actual sores appear. 2  Mouth irritation. 3  The irritation can be caused by: 4  Biting your cheek, tongue, or lip. 5  Wearing braces or another type of dental apparatus, or having a sharp, broken tooth.
Main Image: The Pituitary gland is a pea-sized endocrine (hormone-producing) gland weighing about 0.5 g situated at the bottom of the skull sandwiched between the optic nerves, in humans. The pituitary gland secretes hormones. Hormones are chemicals that travel through the blood stream.
Pituitary gland is called the master gland as it direct the other endocrine glands like thyroid, adrenal and gonads to secrete their hormones. Pituitary glands secrete stimulating hormones which goes via blood to the target endocrine glands which in turn release its hormone.