$18,750 unfavorable variable overhead spending variance = $360,000 â $341,250. Variance is unfavorable because the actual variable overhead costs are higher than the expected costs given actual hours of 97,500. $68,250 unfavorable variable overhead efficiency variance = $341,250 â $273,000.
The function of cytotoxic T cells, also called killer T cells or cytotoxic T lymphocytes, is to protect the body from disease and infection. They do so by killing diseased cells. T cells are white blood cells that are part are the body's immune system. White blood cells defend your body against disease, cancer, infections and foreign substances.
Intracellular CTLA4 is also found in regulatory T cells and may be important to their function. T cell activation through the T cell receptor and CD28 leads to increased expression of CTLA-4, an inhibitory receptor for B7 molecules. The mechanism by which CTLA-4 acts in T cells remains somewhat controversial.