1 Cold sores later crust over with a scab and are usually associated with tingling, tenderness, or burning before the actual sores appear. 2  Mouth irritation. 3  The irritation can be caused by: 4  Biting your cheek, tongue, or lip. 5  Wearing braces or another type of dental apparatus, or having a sharp, broken tooth.
Main Image: The Pituitary gland is a pea-sized endocrine (hormone-producing) gland weighing about 0.5 g situated at the bottom of the skull sandwiched between the optic nerves, in humans. The pituitary gland secretes hormones. Hormones are chemicals that travel through the blood stream.
The hormones produced by these glands function as messengers, and they are carried through the blood stream to other organs throughout the body, where they help regulate bodily functions that range from growth to reproduction. Some of the major endocrine glands are located in the brain, including the pineal gland, pituitary gland, and hypothalamus. The hypothalamus is seen as the switchboard of the endocrine system, connecting the nervous system to the endocrine system, and is responsible for providing hormones that cause other glands to start or stop producing hormones of their own.