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Symptoms. Usually there are no symptoms. If the protein loss is heavy, the urine has a frothy appearance, and would most likely be associated with other symptoms e.g. oedema, where there is an excess of water in the body tissues. Possible causes of proteinuria
Proteinuria itself may cause heavy foaming of the urine. However, patients with proteinuria and no obvious fluid overload may not report any symptoms. Review of systems seeks symptoms suggesting cause, including red or brown urine (glomerulonephritis) or bone pain (myeloma).