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He said that results of this study suggest that there may be two separate ways the brain communicates with the spleen to regulate immune function. This points the way to a possible solution for treating sepsis. It may be more effective to take advantage of the central nervous system to control cells of the spleen.
The endocrine system broadcasts its hormonal messages to essentially all cells by secretion into blood and extracellular fluid. Endocrine system is chemical and slow in nature. The nervous system exerts point-to-point over body control through nerves. Nervous system control is electrical in nature and fast.