a cold sore usually passes through several stages tingling and itching many people feel an itching burning or tingling sensation around their lips for a day or so before a small hard painful spot appears and blisters erupt blisters small fluid filled blisters typically break out along the border where the outside edge of the lips meets the skin of the face
This is because as people age, their bones become more fragile and thus trauma in the elderly tends to cause outright bone fractures instead of soft tissue damage. The most frequently encountered ligamentous injury of the wrist is scapholunate instability.
In what sense may prophase and telophase in mitosis be characterized as opposites. In telophase, the spindle formed in prophase comes undone. The nuclear envelope that broke down in prophase has reformed and multiplied into two. Whatever occurs in prophase is opposite in telophase.