Just as on the demand side, the position of the supply can shift, say from a change in the price of a productive input or a technical improvement. The Law of Supply states that, in general, a rise in price leads to an expansion in supply and a fall in price leads to a contraction in supply.
Puberty takes place over a number of years, and the age at which it starts and ends varies widely. It generally begins somewhere between the ages of 7 and 13 for girls, and somewhere between the ages of 9 and 15 for guys, although it can be earlier or later for some people.
Although mortality from early-onset type 1 DM (onset age, 0-14 y) has declined, the same may not be true for late-onset type 1 DM (onset age, 15-29 y). One study suggest that women tend to fare worse in both cohorts and that alcohol and drug use account for more than one third of deaths.