Birth defects or genetic disorders can also be caused by a problem with the number or structure of chromosomes. Usually this results in multiple body systems being affected. Approximately 1% of all babies will be born with chromosomal abnormality, which can cause physical problems and mental retardation. 2  More than 20% of infant deaths are caused by birth defects or genetic conditions (e.g. congenital heart defects, abnormalities of the nervous system, or chromosomal abnormalities).
We tend to put the fridge on at least 24 hours before departure. How quickly it gets cool can be influenced by the ambient temperature. Although it should cool down overnight. If you don't think its getting cold enough on mains it might be worth trying to cool it down initially on gas.
Confidence votes 110. It would take about 3-4 hours to cool down and 24 hours to stabilize. It is also faster if you don't turn up the temperature to max because that would only block air flow to the fridge from the freezer until the freezer gets the right temperature.