Other. Temperate deciduous forests are most notable because they go through four seasons. Leaves change color in autumn, fall off in the winter, and grow back in the spring; this adaptation allows plants to survive cold winters.
Hydroxychloroquine (Plaquenil) is considered a disease-modifying anti-rheumatic drug (DMARD), because it can decrease the pain and swelling of arthritis, and it may prevent joint damage and reduce the risk of long-term disability.
Damage to the retina, the light sensitive portion of the inner eye, can occur with long-term use of Plaquenil or chloroquine (Aralen). With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more.