Heart disease: Any disorder that affects the heart. Sometimes the term  heart disease  is used narrowly and incorrectly as a synonym for coronary artery disease.Heart disease is synonymous with cardiac disease but not with cardiovascular disease which is any disease of the heart or blood vessels.mong the many types of heart disease, see, for example: Angina; Arrhythmia; Congenital heart disease; Coronary artery disease (CAD); Dilated cardiomyopathy; Heart attack (myocardial infarction); Heart failure; Hypertrophic cardiomyopathy; Mitral regurgitation; Mitral valve prolapse; and Pulmonary stenosis.
The alanine aminotransferase (ALT) test is typically used to detect liver injury. It is often ordered in conjunction with aspartate aminotransferase (AST) or as part of a liver panel to screen for and/or help diagnose liver disease.
ALT is an enzyme found primarily in the liver that helps your body metabolize protein. ALT levels in the blood are normally low. Levels increase when the liver is damaged and ALT is released into the bloodstream. AST is an enzyme that helps with the metabolism of alanine, an amino acid. AST is normally found in high concentrations but an increase in AST levels may also indicate liver damage or disease.