Marks decided that the show needed to be updated to reflect a new era. Fewer listeners were building their own radios. The music was shortened and a name change was also planned for the middle of 1981, with Media Network being the name suggested by Roger Broadbent, a colleague producer.
The newer second generation antipsychotics (also called atypical antipsychotics) are mostly partial dopamine antagonists. They also block serotonin receptors, and are hence called serotonin dopamine antogonists. A lot of the side effects of the antispychotic medications are also mediated by blockage of the D2 receptor.
First-generation antipsychotics, known as typical antipsychotics, were discovered in the 1950s. Most second-generation drugs, known as atypical antipsychotics, have been developed more recently, although the first atypical antipsychotic, clozapine, was discovered in the 1950s and introduced clinically in the 1970s.t is unclear whether the atypical (second-generation) antipsychotics offer advantages over older, first generation antipsychotics. Amisulpride, olanzapine, risperidone and clozapine may be more effective but are associated with greater side effects.