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Many of these potential Lipitor side effects can affect the liver, including: 1  An increase in liver enzymes. 2  Hepatitis, which is an inflammation of the liver that can cause tiredness or a general feeling of illness.  Jaundice, or yellowing of the skin or eyes that can occur from the liver being damaged.
Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: yellowing eyes and skin, dark urine, change in the amount of urine, vision problems, black stool, severe stomach pain. An allergic reaction to Lipitor is unlikely, but seek immediate medical attention if it occurs.