Other. Temperate deciduous forests are most notable because they go through four seasons. Leaves change color in autumn, fall off in the winter, and grow back in the spring; this adaptation allows plants to survive cold winters.
Hydroxychloroquine (Plaquenil) is considered a disease-modifying anti-rheumatic drug (DMARD), because it can decrease the pain and swelling of arthritis, and it may prevent joint damage and reduce the risk of long-term disability.
The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. The pediatric weekly suppressive dosage is 5 mg/kg of body weight. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days. To treat lupus erythematosus, the average adult dose is 400 mg once or twice daily.