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Many of these diseases are genetic. Sometimes the cause is a medical condition such as alcoholism, a tumor, or a stroke. Other causes may include toxins, chemicals, and viruses. Sometimes the cause is not known. Degenerative nerve diseases include. 1  Alzheimer's disease. 2  Amyotrophic lateral sclerosis.
degenerative disease. a disease in which the sole pathogenesis is degeneration; that is without the intervention of other pathogeneses, e.g. inflammation, traumatic injury, neoplasia. degenerative joint disease. see degenerative joint disease.degenerative left shift. an increase in immature neutrophilic granulocytes, in excess of mature cells of the series, with a normal or increased white blood cell count. A poor prognostic sign, indicating an inability of the bone marrow to respond adequately to infection.egenerative disease. a disease in which the sole pathogenesis is degeneration; that is without the intervention of other pathogeneses, e.g. inflammation, traumatic injury, neoplasia. degenerative joint disease. see degenerative joint disease.