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The dry heat sterilization process takes much longer even at higher temperatures than steam sterilization. For dry heat sterilization at a temperature of 180Â°C an exposure time of 30 minutes is needed. I hope this will help you to understand the nature of steam and the critical role it plays in the sterilization process. Generating the ideal conditions for saturated steam will positively impact the sterilization results. Wet steam or superheated steam are problematic.