Some transcription factors bind to a DNA promoter sequence near the transcription start site and help form the transcription initiation complex. Other transcription factors bind to regulatory sequences, such as enhancer sequences, and can either stimulate or repress transcription of the related gene.ranscription factors include a wide number of proteins, excluding RNA polymerase, that initiate and regulate the transcription of genes.
Follow the label directions on how often to take this medication. If you are taking a single dose a day, take it in the morning with your breakfast or right away after eating your breakfast. If you are taking more than one dose a day, take the last dose no later than 4 p.m. The number of doses you take each day, the time allowed between doses, and how long you need to take the medication will depend on the type of diuretic prescribed, as well as your condition.
Most thiazide diuretics are taken once a day in the morning. Any reduction in blood pressure is maintained throughout the 24 hours by this once-a-day dose. But, the effect of passing extra urine wears off within 12 hours. So, you will not have to get up in the night to make extra trips to the toilet.