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Symptoms. Usually there are no symptoms. If the protein loss is heavy, the urine has a frothy appearance, and would most likely be associated with other symptoms e.g. oedema, where there is an excess of water in the body tissues. Possible causes of proteinuria
What are the signs of proteinuria and kidney failure? Large amounts of protein in your urine may cause it to look foamy in the toilet. Also, because the protein has left your body, your blood can no longer soak up enough fluid and you may notice swelling in your hands, feet, abdomen, or face. These are signs of very large protein loss.