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Many of these potential Lipitor side effects can affect the liver, including: 1  An increase in liver enzymes. 2  Hepatitis, which is an inflammation of the liver that can cause tiredness or a general feeling of illness.  Jaundice, or yellowing of the skin or eyes that can occur from the liver being damaged.
Studies have found that side effects of Lipitor may increase the risk of diabetes and other serious health complications associated with the disease, especially among otherwise health women prescribed the cholesterol drug.