Birth defects or genetic disorders can also be caused by a problem with the number or structure of chromosomes. Usually this results in multiple body systems being affected. Approximately 1% of all babies will be born with chromosomal abnormality, which can cause physical problems and mental retardation. 2  More than 20% of infant deaths are caused by birth defects or genetic conditions (e.g. congenital heart defects, abnormalities of the nervous system, or chromosomal abnormalities).
We tend to put the fridge on at least 24 hours before departure. How quickly it gets cool can be influenced by the ambient temperature. Although it should cool down overnight. If you don't think its getting cold enough on mains it might be worth trying to cool it down initially on gas.
So here is a quick defrosting trick that only takes you about 10 minutes tops to remove the ice. The trick is to use your hair dryer! Here are quick steps to defrost your fridge: Turn the fridge off and open the fridge and freezer doors, then remove all items and put them in a cool spot. It will only take 10 minutes and most things will survive. You could use some ice blocks and a cooler box for ice cream and other foods that spoil quickly.