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Many of these potential Lipitor side effects can affect the liver, including: 1  An increase in liver enzymes. 2  Hepatitis, which is an inflammation of the liver that can cause tiredness or a general feeling of illness.  Jaundice, or yellowing of the skin or eyes that can occur from the liver being damaged.
The side effects of Lipitor (atorvastatin) are still the same whether the dose is 10 mg or 40 mg. However, a higher dose may increase the potential for side effects. For some patients, the side effects from an increased dose are not noticeable.