Sugar cubes were produced in the nineteenth century. The first inventor of a process to make sugar in cube form was Moravian Jakub KryÅ¡tof Rad, director of a sugar company in DaÄice. He began sugar cube production after being granted a five-year patent for the invention on January 23, 1843.Henry Tate of Tate & Lyle was another early manufacturer of sugar cubes at his refineries in Liverpool and London.e began sugar cube production after being granted a five-year patent for the invention on January 23, 1843. Henry Tate of Tate & Lyle was another early manufacturer of sugar cubes at his refineries in Liverpool and London.
ELSI Research Domains. The NHGRI Division of Genomics and Society has identified the following three research domains to be considered for support by the Ethical, Legal and Social Implications (ELSI) Research Program. The domains are overlapping, and it is anticipated that many research projects will address issues that cut across domains.
1 National Human Genome Research Institute (NHGRI) . 2  NHGRI led the National Institutes of Health's contribution to the International Human Genome Project. 3  This project, which had as its primary goal the sequencing of the three thousand million base pairs that make up human genome, was successfully completed in April 2003.long with identifying all of the approximately 20,000â25,000 genes in the human genome, the Human Genome Project also sought to address the ethical, legal, and social issues that were created by the onset of the project. For that the Ethical, Legal, and Social Implications (ELSI) program was founded in 1990.