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100% activity is attained after 24 hours. It is also described therein that, 6 hours after oral administration to cats, nitenpyram reaches an activity of 60% against the fleas present on the cats, and on the second day after renewed infestation it still gives 55% activity.
In clinical trials, NexiumÂ® 24HR has been shown to treat frequent heartburn for up to 24 hours when taken once each morning before eating for 14 consecutive days. NexiumÂ® 24HR should be taken only as directed, unless otherwise determined by a healthcare professional.