Pulmonary surfactant is a surface-active lipoprotein complex (phospholipoprotein) formed by type II alveolar cells. The proteins and lipids that make up the surfactant have both hydrophilic and hydrophobic regions.
Antibody deficiencies, also called immunoglobulin deficiency syndromes, are immune system disorders that are characterized by low or absent levels of immunoglobulin in the blood.Immunoglobulins (Ig) are antibodies that play an essential role in the body's immune system.he antibodies are present in the bloodstream or bound to the outer surfaces of B-cells or plasma cells. There are five classes of immunoglobulins: IgA, IgD, IgE, IgG, and IgM. Patients who have antibody deficiencies may have reduced or absent levels of one or more types of immunoglobulin.
The pathology of Goodâs syndrome suggests at least two possible pathogenic mechanisms for the association of antibody deficiency with thymoma. The first explanation is that cytokines, possibly secreted by bone marrow stromal cells, may influence both thymic and B cell precursor growth and differentiation.