Other. Temperate deciduous forests are most notable because they go through four seasons. Leaves change color in autumn, fall off in the winter, and grow back in the spring; this adaptation allows plants to survive cold winters.
Hydroxychloroquine (Plaquenil) is considered a disease-modifying anti-rheumatic drug (DMARD), because it can decrease the pain and swelling of arthritis, and it may prevent joint damage and reduce the risk of long-term disability.
High risk patients would include those who: 1  have taken high doses of Plaquenil for years (i.e., 1000 g. for over 7 years) 2  are 60 years or older. 3  are obese.  have significant liver or kidney 1  disease. have pre-existing retinal, macular disease, or cataracts.