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He said that results of this study suggest that there may be two separate ways the brain communicates with the spleen to regulate immune function. This points the way to a possible solution for treating sepsis. It may be more effective to take advantage of the central nervous system to control cells of the spleen.
Long-distance communication is by means of nerves and circulating hormones; the principal function of many organs, notably the endocrine glands, is to facilitate such communication between organs. Cells communicate with each other by means of an enormous diversity of signalling molecules.These molecules have traditionally been classified according to the distance over which they act. Local communication between neighbouring cells is described as paracrine signalling.ells communicate with each other by means of an enormous diversity of signalling molecules. These molecules have traditionally been classified according to the distance over which they act. Local communication between neighbouring cells is described as paracrine signalling.