The Sodality of the Blessed Virgin was founded in Rome (1563) by Rev. John Leunis, S.J., for the students at the Roman College. At the time of its quadricentennial, the Sodality of the Blessed Virgin was established in more than one hundred countries.
Poor Circulation. Narrowed blood vessels lead to decreased blood flow and oxygen to a wound. An elevated blood sugar level decreases the function of red blood cells that carry nutrients to the tissue. This lowers the efficiency of the white blood cells that fight infection.
That's why frostbite injuries can take so long to heal. Blisters may form within days of your skin thawing out, and that can cause infection. After a week, the blisters may scab over, and dead tissue can fall off.