The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials. The search textbox has an autosuggest feature.
Aldactone Description: Aldactone (spironolactone) is an antagonist of aldosterone and is pharmaceutically classified as a diuretic. It acts by competitively inhibiting aldosterone binding to receptor sites, especially in the renal tubes where aldosterone is involved in sodium-potassium exchange.
spironolactone is a potassium sparing diuretic water pill that prevents your body from absorbing too much salt and keeps your potassium levels from getting too low spironolactone is used to diagnose or treat a condition in which you have too much aldosterone in your bodyaldosterone is a hormone produced by your adrenal glands to help regulate the salt and water balance in your bodypironolactone also treats fluid retention edema in people with congestive heart failure cirrhosis of the liver or a kidney disorder called nephrotic syndrome this medication is also used to treat or prevent hypokalemia low potassium levels in the blood