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Unicellular organisms are composed of a single cell. Multicellular organisms are composed of many specialized cells. Specialized cells differ in structure (size, shape...) and function (the role they perform in the organism).
Complexity-Higher tier. Multicellular organisms need specialised organ systems, whereas all the life processes in a unicellular organism take place in that one cell. Multicellular organisms need organ systems to carry out functions such as: 1  Communication between cells, eg the nervous system and circulatory system.