The UK's most valuable monument is deemed to be the 1,000-year-old Tower of London, which is worth an estimated Â£56billion to the British economy and came it at number five in the list of European list. Its value is six times more than its nearest rival the Colosseum in Rome, which is valued at Â£72billion.
Cell cycle checkpoints are control mechanisms in eukaryotic cells which ensure proper division of the cell.
The G1/S cell cycle checkpoint controls the passage of eukaryotic cells from the first gap phase, G1, into the DNA synthesis phase, S. In this switch in mammalian cells, there are two cell cycle kinases that help to control the checkpoint: cell cycle kinases CDK4/6-cyclin D and CDK2-cyclin E.