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autoimmune disease an illness that occurs when the body tissues are attacked by its own immune system the immune system is a complex organization within the body that is designed normally to seek and destroy invaders of the body including infectious agents
Some autoimmune diseases include: 1  Lupus is a chronic disease marked by muscle and joint pain and inflammation. 2  Juvenile idiopathic arthritis is a disease in which the body's immune system acts as though certain body parts such as the joints of the knee, hand, and foot are foreign tissue and attacks them.