1 Cold sores later crust over with a scab and are usually associated with tingling, tenderness, or burning before the actual sores appear. 2  Mouth irritation. 3  The irritation can be caused by: 4  Biting your cheek, tongue, or lip. 5  Wearing braces or another type of dental apparatus, or having a sharp, broken tooth.
Main Image: The Pituitary gland is a pea-sized endocrine (hormone-producing) gland weighing about 0.5 g situated at the bottom of the skull sandwiched between the optic nerves, in humans. The pituitary gland secretes hormones. Hormones are chemicals that travel through the blood stream.
Hormones are produced by various organs and body tissues, but mainly by the endocrine glands, such as the pituitary, thyroid, and gonads (testes and ovaries). Each gland apparently synthesizes several kinds of hormones; the adrenal glands alone produce more than 25 varieties.