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Quick Answer. Ibuprofen has a shelf life of 24 to 36 months, depending on its packaging. Tablets packed in aluminium foils and amber colored glass bottles can be consumed for up to 36 months. Ibuprofen packed in a HDPE bottle should consumed within 24 months. Continue Reading.
There are two ways of approaching this question: one of how long is it effective in your system (providing the effects for which you took the drug) and the other of how long until it is eliminated. Effectiveness: The half-life of ibuprofen (the time after which half the dose has been eliminated) is about 2 hours.