1 2 tablespoons of ground coffee for each 6 ounces of water, or 30 ml of coffee per 180 ml of water. This ratio is appropriate for most manual and electric brewing systems but there are some exceptions (see Step 2 Tips).  A âcupâ from most automatic drip makers measures 5 ounces, so adjust accordingly. For instance, a 12 cup automatic would require 20 tablespoons of ground coffee. Note: many coffee scoops measure 2 tablespoons.
Related to De novo mutation: back mutation, conditional mutant. [mu-taÂ´shun] 1. a permanent transmissible change in the genetic material. 2. an individual exhibiting such a change. point mutation a mutation resulting from a change in a single base pair in the DNA molecule. somatic mutation a genetic mutation occurring in a somatic cell, providing the basis for mosaicism. suppressor mutation the correction of the effect of a mutation at one locus by a mutation at another locus.
Substitution mutation. Definition. A type of point mutation in which a single nucleotide is substituted with (or exchanged for) a different nucleotide that may result in an altered sequence of amino acid during translation, which may render the newly synthesized protein ineffective. Supplement.