Cymbalta is used to treat major depressive disorder and general anxiety disorder. It is also used to treat a chronic pain disorder called fibromyalgia, and to treat pain caused by nerve damage in people with diabetes (diabetic neuropathy).
Caffeine-withdrawal headaches can last up to 48 hours and can be as intense as a migraine headache. Withdrawal symptoms can begin 12 to 24 hours after the last cup of coffee and can last up to 1 week. These symptoms can include lethargy, extreme nervousness, irritability, sweating, headaches and shakiness.
Withdrawal symptoms can onset within 12 to 24 hours of caffeine consumption and last between 2 and 9 days. There are more cognitive concerns here as well. For one, caffeine probably follows the Yerkes-Dodson law, in which a moderate dose is superior to too little or too much.