Cymbalta is used to treat major depressive disorder and general anxiety disorder. It is also used to treat a chronic pain disorder called fibromyalgia, and to treat pain caused by nerve damage in people with diabetes (diabetic neuropathy).
Caffeine-withdrawal headaches can last up to 48 hours and can be as intense as a migraine headache. Withdrawal symptoms can begin 12 to 24 hours after the last cup of coffee and can last up to 1 week. These symptoms can include lethargy, extreme nervousness, irritability, sweating, headaches and shakiness.
His research suggested that withdrawals began within 12â24 hours after stopping caffeine intake and could last as long as nine days. Continued exposure to caffeine will lead the body to create more adenosine receptors in the central nervous system which makes it more sensitive to the effects of adenosine in two ways.