Birth defects or genetic disorders can also be caused by a problem with the number or structure of chromosomes. Usually this results in multiple body systems being affected. Approximately 1% of all babies will be born with chromosomal abnormality, which can cause physical problems and mental retardation. 2  More than 20% of infant deaths are caused by birth defects or genetic conditions (e.g. congenital heart defects, abnormalities of the nervous system, or chromosomal abnormalities).
We tend to put the fridge on at least 24 hours before departure. How quickly it gets cool can be influenced by the ambient temperature. Although it should cool down overnight. If you don't think its getting cold enough on mains it might be worth trying to cool it down initially on gas.
So exactly what temperature should a fridge be? Your fridge should be cooling food anywhere in between 36 and 40 degrees Fahrenheit (2.2 to 4.5 degrees Celsius). How do you test this? Use a probe thermometer to gauge the temperature of the inside of food that has been sitting in your fridge for at least 24 hours.