The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials. The search textbox has an autosuggest feature.
Aldactone Description: Aldactone (spironolactone) is an antagonist of aldosterone and is pharmaceutically classified as a diuretic. It acts by competitively inhibiting aldosterone binding to receptor sites, especially in the renal tubes where aldosterone is involved in sodium-potassium exchange.
spironolactone for acne spironolactone is sometimes used off label to treat women with persistent adult acne due to increased androgen levels because the drug is able to inhibit the activity of sebaceous glands small skin glands that releases an oily lubricating substance called sebumhe drug is used to treat a condition called primary hyperaldosteronism in which the body produces excess amounts of the hormone aldosterone which regulates your body s sodium and water levels spironolactone helps restore a healthy balance of sodium and potassium in your body it s also used to treat