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Many of these diseases are genetic. Sometimes the cause is a medical condition such as alcoholism, a tumor, or a stroke. Other causes may include toxins, chemicals, and viruses. Sometimes the cause is not known. Degenerative nerve diseases include. 1  Alzheimer's disease. 2  Amyotrophic lateral sclerosis.
Degenerative central nervous system diseases. The diseases are characterised by loss of motor control, dementia, paralysis, wasting and eventually death, typically following pneumonia. Visible end results at post-mortem are non- inflammatory lesions, vacuoles, amyloid protein deposits and astrogliosis.