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ANCA : Antineutrophil cytoplasmic antibodies (ANCA) can occur in patients with autoimmune vasculitis including Wegener's granulomatosis (WG), microscopic polyangiitis (MPA), or organ-limited variants thereof such as pauci-immune necrotizing glomerulonephritis.(1) Detection of ANCA is a well-established diagnostic test for the evaluation of patients suspected of having autoimmune vasculitis.
P-ANCA and c-ANCA are microscopic tests that check for vasculitis. C-ANCA and p-ANCA are two tests used in the diagnosis and evaluation of rheumatologic diseases.These conditions often result from a dysfunction in the immune system, which triggers an attack on certain tissues in the body that it mistakes as foreign or invading microorganisms or poisons.he p-ANCA test shows the presence of antineutrophil antibodies around the nucleus of cells. P-ANCA and c-ANCA are usually seen in conditions like Wegener's granulomatosis, and other vasculitides.