The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials. The search textbox has an autosuggest feature.
Aldactone Description: Aldactone (spironolactone) is an antagonist of aldosterone and is pharmaceutically classified as a diuretic. It acts by competitively inhibiting aldosterone binding to receptor sites, especially in the renal tubes where aldosterone is involved in sodium-potassium exchange.
This medicine may also be used to treat fluid retention (edema) in patients with congestive heart failure, liver cirrhosis, or a kidney disorder called nephrotic syndrome. Spironolactone is a potassium-sparing diuretic (water pill).It prevents your body from absorbing too much salt and keeps your potassium levels from getting too low. This medicine is also used to treat or prevent hypokalemia (low potassium levels in the blood).pir-on-oh-LAK-tone. Treats high blood pressure. Also treats edema (fluid retention) or high levels of aldosterone (a hormone). This medicine is a potassium-sparing diuretic (water pill).