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Many of these diseases are genetic. Sometimes the cause is a medical condition such as alcoholism, a tumor, or a stroke. Other causes may include toxins, chemicals, and viruses. Sometimes the cause is not known. Degenerative nerve diseases include. 1  Alzheimer's disease. 2  Amyotrophic lateral sclerosis.
Degenerative diseases - Parkinsonâs disease, nigrostriatal degeneration, dementing diseases such as Alzheimerâs and Pickâs Multiple or bilateral strokes affecting basal ganglia Toxic-metabolic - antipsychotic medications, MPTP, chronic heavy metal exposure, Wilsonâs Diseas