As with other angiotensin II receptor antagonists, candesartan is indicated for the treatment of hypertension. Results from the CHARM study (early 2000s) demonstrated the morbidity and mortality reduction benefits of candesartan therapy in congestive heart failure.uring the first two years of the trial, half of participants were given candesartan, and the others received placebo; candesartan reduced the risk of developing hypertension by nearly two-thirds during this period. In the last two years of the study, all participants were switched to placebo.
Single Instance Storage. The Single Instance Storage (SIS) feature reduces the amount of space that is used to store data on a volume. SIS does this by replacing duplicate files with logical links that point to a single copy of the file in the SIS Common Store, which is a hidden folder that is located in the root directory of the volume.
Single Node or Psuedo-Distributed Cluster is the one in which all the essential daemons (like NameNode, DataNode, JobTracker and TaskTracker) run on the same machine. The default replication factor for a single node cluster is 1. A single node cluster is basically used to simulate a full cluster like environment and to test hadoop applications and unlike the Stand-alone mode, HDFS is accessible in this.