Born in Boston, the son of touring actors David Poe Jr. and Elizabeth Arnold Poe. When he was three years old, his parents died, and he was taken into the home of John Allan, a wealthy merchant in Richmond, Virginia, who renamed him Edgar Allan Poe. In 1826 he entered the University of Virginia, staying only one year, and running up large gambling debts that John Allan refused to pay.
It is found in almost all body tissues and can be measured by a simple blood test. Normal LDH levels are generally low and range between 140 IU/liter to 333 IU/ liter. Low LDH levels are usually no cause for concern. However, elevated LDH levels may indicate cell damage.
A lactate dehydrogenase (LDH or LD) is an enzyme found in nearly all living cells (animals, plants, and prokaryotes). LDH catalyzes the conversion of pyruvate to lactate and back, as it converts NADH to NAD + and back. A dehydrogenase is an enzyme that transfers a hydride from one molecule to another. LDH exist in four distinct enzyme classes. This article is about the common NAD(P)-dependent L-lactate dehydrogenase.