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For ALL, chemotherapy may be given into the fluid surrounding the brain and spinal cord. This is called intrathecal chemotherapy.
Intrapleural chemo treatments Chemotherapy can be given into the pleural cavity (the space between the lung and the lining of the lung). Intrapleural chemotherapy is used to control malignant pleural effusions. A malignant pleural effusion is an accumulation of cancerous fluid in the pleural space.