The half-life of the ketorolac tromethamine S-enantiomer was approximately 2.5 hours (SD Â± 0.4) compared with 5 hours (SD Â± 1.7) for the R-enantiomer. In other studies, the half-life for the racemate has been reported to lie within the range of 5 to 6 hours.
Proton pump inhibitors (PPIs) are a group of drugs whose main action is a pronounced and long-lasting reduction of gastric acid production. Within the class of medications, there is no clear evidence that one agent works better than another. They are the most potent inhibitors of acid secretion available.
How Do Proton Pump Inhibitors Work? Proton pump inhibitors (PPIs) block the enzyme in the wall of the stomach that produces acid, lowering the amount of acid in the environment. Acid is the culprit behind heartburn, and tamping down production of stomach acid can help ease the discomfort of this bothersome symptom.