Stand alone vs standalone Stand alone is an idiom meaning one who is unequaled or without peer, notice that the verb form is two separate words. 1 To 1 English native Teachers, the best way to improve your English! Click here to find out more!
From Wikipedia, the free encyclopedia. Epigenetics is the study of changes in gene activity which are not caused by changes in the DNA sequence. It is the study of gene expression, the way genes bring about their phenotypic effects.
Cancer initiation and progression are accompanied by profound changes in DNA methylation that were the first epigenetic alterations identified in cancer (67, 68). A cancer epigenome is marked by genome-wide hypomethylation and site-specific CpG island promoter hypermethylation (Figure 2) (3).bstract. Epigenetic mechanisms are essential for normal development and maintenance of tissue-specific gene expression patterns in mammals. Disruption of epigenetic processes can lead to altered gene function and malignant cellular transformation. Global changes in the epigenetic landscape are a hallmark of cancer.