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The acute effects of marijuana (THC and other associated cannabinoids) include: 1  Euphoria. 2  Dry mouth. 3  Reddening of eyes. 4  Decrease in intra-ocular pressure. 5  Muscle relaxation. 6  Depersonalization. 7  Increased appetite. 8  Effects on attention. 9  Altered visuospatial reasoning. 10  Altered time sense. 11  Lethargy. 12  Drowsiness. 13  Occasional anxiety and paranoia.
No matter how you use marijuana, the drug can cause immediate and long-term effects, such as changes in perception and increased heart rate. Over time, smoking marijuana may cause chronic cough and other health issues. The effects of marijuana on the body are often immediate. Longer-term effects may depend on how you take it, how much you use, and how often you use it. The exact effects are hard to determine because marijuana has been illegal in the U.S., making studies difficult and expensive to conduct.