Leaf spot first appears in rainy or humid weather as the plants are growing. They look like small brown spots with a water-soaked margin surrounded by a yellow halo usually on the upper halves of the iris leaves.
Two, caffeine enhances the sensation and contractility of the bladder. Another way caffeine can affect prostate health is through its ability to irritate the bladder because it is a theoxanthine, a family of drugs that includes theobromine (found in chocolate) and theophylline (found in tea). Theophylline also stimulates and irritates the bladder.
Pin It. The caffeine in coffee has been linked to cancer of the liver, bladder, kidney, and pancreas. But the research on the carcinogenicity of caffeine to support these claims was often anecdotal or fraught with inaccuracies and remains difficult to duplicate and validate. Coffee is a complex chemical compound.