The most common immediate adverse reactions to transfusion are fever, chills and urticaria. The most potentially significant reactions include acute and delayed haemolytic transfusion reactions and bacterial contamination of blood products.
Penicillin allergy is an overreaction by your immune system to penicillin and other antibiotics in the beta-lactam family and closely related antibiotics. Doxycycline belongs to a class of drugs called Tetracyclines. Tetracyclines are unrelated to penicillins and therefore safe to take in hypersensitive patients. Other unrelated antibiotics include quinolones (e.g. ciprofloxacin), macrolides (e.g. clarithromycin), aminoglycosides (e.g. gentamicin) and glycopeptides (e.g. vancomycin).
Doxycycline hyclate is part of a class of drugs called tetracyclines. It decreases bacteria's ability to make protein, which the bacterium needs to live. By affecting the protein of bacteria, the drug helps stop bacteria from continuing to live and cause infection in the body.