It became clear that, in order to fully implement the intent of the streamlining initiative, CSAVR, its member state agencies, and RSA needed to agree on some fundamental changes in policy and practice. To accomplish its goal, the RSA provides its members with leadership and service.
Methadone, sold under the brand names Dolophine among others, is an opioid used to treat pain and as maintenance therapy or to help with detoxification in people with opioid dependence. Detoxification using methadone can either be done relatively rapidly in less than a month or gradually over as long as six months.
Methadoneâenantiomers, quantitation in humans using stable isotope labeling; Enantiomersâof methadone, quantitation in humans using stable isotope labeling; Narcoticsâmethadone, quantitation of enantiomers in humans using stable isotope labeling Abstract A new technique for simultaneous stereoselective kinetic studies of methadone enantiomers was developed using three deuterium-labeled forms of methadone and GLC-chemical-ionization mass spectrometry. A racemic mixture (1:1) of (R)-(-)-[2 H 5]methadone (l-form) and (S)-(+)-[2 H 3]methadone (d-form) was administered orally in place of a single daily dose of unlabeled (Â±)-[2 H 8]methadone in longterm maintenance patients.