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ALS, also known as Lou Gehrig's disease, Charcot's disease, and motor neuron disease (MND), attacks certain cells in the brain and spinal cord needed to keep our muscles moving. Early signs and symptoms of ALS include: muscle cramps and muscle twitching.
Expert answer. Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a progressive, neurodegenerative disorder that causes muscle weakness. It is incurable and eventually fatal. It occurs at a very low incidence, about one to three cases per 100,000 people.