Here's where things get fun. Just like the number of reps, 3-6 sets is the best range of volume for this training method. If you like your workouts paced like clockwork, take 30-60 seconds rest between each exercise.
The natural attraction between positive and negative keeps the ions surrounded by water molecules and therefore dissolved in solution. Many biochemicals are either polar molecules or charged ions (or both) so water makes an excellent solvent for them.
Water is only a quasi-universal solvent. The chemical and physical properties of water are very suitable for a good solvent.   Water is not totally universal.