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Bone replaces cartilage here in the same way as it does in the primary centers. However, cartilage remains in two places: (1) on the articular surfaces of joints, and (2) as a transverse epiphyseal plate between the epiphyses and diaphysis. After adult stature is reached, the epiphyseal plate is replaced by bone.
The cartilage surfaces behind the kneecap are the thickest in the entire human body and usually begin to wear out after the age of 15. Almost all people have evidence of cartilage damage on kneecap cartilage when we perform arthroscopic surgery. It is interesting to note however that while the pain from chondromalacia is the most common complaint of people between the ages of 15 and 60, these complaints usually disappear after age of 60.