Acute Hepatic Failure in Dogs. Acute hepatic failure is a condition characterized by the sudden loss of 70 percent or more of the liver's function due to sudden, massive, hepatic necrosis (tissue death in the liver).
Key Points. Secondary (acquired) immunodeficiencies are much more common than primary (hereditary) immunodeficiencies. Primary immunodeficiencies can affect humoral immunity (most commonly), cellular immunity, both humoral and cellular immunity, phagocytic cells, or the complement system.
However, some disadvantages do exist in this method. Since the number of fluorescent molecules that can be bound to the primary antibody is limited, direct immunofluorescence is substantially less sensitive than indirect immunofluorescence and may result in false negatives.