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Symptoms of mononucleosis generally resemble those of the flu and include fever, sore throat, and swollen lymph glands. Sometimes, a swollen spleen or liver involvement may develop. These symptoms usually last for more than two days and may appear slowly.
The most common symptoms of mono are: 1  Fever, which may range from 101Â°F (38.3Â°C) to 104Â°F (40Â°C) , and chills. 2  Sore throat, often with white patches on the tonsils (which may look like strep throat). 3  Swollen lymph nodes all over the body, especially the lymph nodes in the neck.4  Swollen tonsils.5  Headache or body aches.ot everyone infected with the virus that causes mono (Epstein-Barr virus, or EBV) has symptoms. This is especially true for young children, who may have a fever but no other symptoms. People ages 15 to 24 are most likely to have obvious symptoms.