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The acute effects of marijuana (THC and other associated cannabinoids) include: 1  Euphoria. 2  Dry mouth. 3  Reddening of eyes. 4  Decrease in intra-ocular pressure. 5  Muscle relaxation. 6  Depersonalization. 7  Increased appetite. 8  Effects on attention. 9  Altered visuospatial reasoning. 10  Altered time sense. 11  Lethargy. 12  Drowsiness. 13  Occasional anxiety and paranoia.
Marijuana overactivates parts of the brain that contain the highest number of these receptors. This causes the high that users feel. Other effects include: 1  altered senses (for example, seeing brighter colors). 2  altered sense of time.