The most common immediate adverse reactions to transfusion are fever, chills and urticaria. The most potentially significant reactions include acute and delayed haemolytic transfusion reactions and bacterial contamination of blood products.
Penicillin allergy is an overreaction by your immune system to penicillin and other antibiotics in the beta-lactam family and closely related antibiotics. Doxycycline belongs to a class of drugs called Tetracyclines. Tetracyclines are unrelated to penicillins and therefore safe to take in hypersensitive patients. Other unrelated antibiotics include quinolones (e.g. ciprofloxacin), macrolides (e.g. clarithromycin), aminoglycosides (e.g. gentamicin) and glycopeptides (e.g. vancomycin).
Doxycycline is an antibiotic that is used in the treatment of a number of types of infections caused by bacteria and protozoa. It is useful for bacterial pneumonia, acne, chlamydia infections, early Lyme disease, cholera and syphilis. It is also useful for the treatment of malaria when used with quinine and for the prevention of malaria.