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AST (aspartate aminotransferase) is an enzyme found in high amounts in liver, heart, and muscle cells. It is also found in lesser amounts in other tissues. This article discusses the test to measure the amount of AST in the blood.
An aspartate aminotransferase (AST) test measures the amount of this enzyme in the blood. AST is normally found in red blood cells, liver, heart, muscle tissue, pancreas, and kidneys. AST formerly was called serum glutamic oxaloacetic transaminase (SGOT).n aspartate aminotransferase (AST) test is done to: 1  Check for liver damage. 2  Help identify liver disease, especially hepatitis and cirrhosis. 3  Check on the success of treatment for liver disease. 4  Find out whether jaundice was caused by a blood disorder or liver disease. 5  Keep track of the effects of medicines that can damage the liver.