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1 Breathing problems. 2  Marijuana smoke irritates the lungs, and frequent marijuana smokers can have the same breathing problems that tobacco smokers have. 3  These problems include daily cough and phlegm, more frequent lung illness, and a higher risk of lung infections.
Marijuana overactivates parts of the brain that contain the highest number of these receptors. This causes the high that users feel. Other effects include: 1  altered senses (for example, seeing brighter colors). 2  altered sense of time.