Offside in open play Offside is quite a complicated rule of rugby union, so make sure you pay attention and listen to what the referee is saying. If a player is in front of a team-mate in possession of the ball, or in front of their team-mate who last played the ball, they will be offside if: 1  They are actively trying to play the ball. 2  Do not retire within 10m of an opponent who is waiting for the ball.
FRAMESHIFT MUTATION. This type of mutation occurs when the addition or loss of DNA bases changes a geneÂ´s reading frame. Extra base pairs may be added (insertions) or removed (deletions) from the DNA of a gene. The number can range from one to thousands. Collectively, these mutations are called indels.
Best Answer: Dear Rose, A point mutation, or single base substitution, is a type of mutation that causes the replacement of a single base nucleotide with another nucleotide of the genetic material, DNA or RNA.Often the term point mutation also includes insertions or deletions of a single base pair.his is an example of a non-conservative (missense) mutation. Point mutations that occur in non-coding sequences are most often without consequences, although there are exceptions. If the mutated base pair is in the promoter sequence of a gene, then the expression of the gene may change.