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The zygomaticus major is a muscle of the human body. It is a muscle of facial expression which draws the angle of the mouth superiorly and posteriorly (smile).he zygomaticus major is a muscle of the human body. It is a muscle of facial expression which draws the angle of the mouth superiorly and posteriorly (smile).
Synonyms: musculus zygomaticus major, greater zygomatic muscle, musculus zygomaticus. The definition information for zygomaticus major (muscle) is provided by Stedman's. You can search our medical dictionary here.Stedman's, part of Lippincott Williams & Wilkins, provides a comprehensive line of health-science publications for healthcare professionals and medical students.efinitions: 1. facial muscle of anterior cheek extending to upper lip; origin, zygomatic bone anterior to temporozygomatic suture; insertion, muscles at angle of mouth; action, draws upper lip upward and laterally; nerve supply, facial.