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For ALL, chemotherapy may be given into the fluid surrounding the brain and spinal cord. This is called intrathecal chemotherapy.
When used with other treatments, chemotherapy can: 1  Make a tumor smaller before surgery or radiation therapy. 2  Destroy cancer cells that may remain after treatment with surgery or radiation therapy. 3  Help other treatments work better. 4  Kill cancer cells that have returned or spread to other parts of your body.hen used with other treatments, chemotherapy can: 1  Make a tumor smaller before surgery or radiation therapy. 2  This is called neoadjuvant chemotherapy. 3  Destroy cancer cells that may remain after treatment with surgery or radiation therapy. 4  This is called adjuvant chemotherapy. 5  Help other treatments work better.