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Symptoms of mononucleosis generally resemble those of the flu and include fever, sore throat, and swollen lymph glands. Sometimes, a swollen spleen or liver involvement may develop. These symptoms usually last for more than two days and may appear slowly.
Mono usually comes on over a few days. It begins with flu-like symptoms -- fever, headache, and general malaise and lethargy. After a few days, the lymph glands begin to swell, although this symptom is not noticeable in everyone.Swollen glands of the neck are especially typical of mono.Most people develop a sore throat, which can be very severe, with inflamed tonsils. A fever -- usually no higher than 104 degrees -- also can develop and may last up to three weeks.ononucleosis, often referred to as mono, is a very common viral illness. About 90% of people over 35 have been infected with it, probably during early childhood, and have antibodies to the virus in their blood.