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Osmolality of blood increases with dehydration and decreases with overhydration. In normal people, increased osmolarity in the blood will stimulate secretion of antidiuretic hormone (ADH). This will result in increased water reabsorption, more concentrated urine, and less concentrated blood plasma.
Plasma osmolarity: The osmolarity of blood plasma, which is a measure of the hydration status. The plasma osmolarity is sensitive to changes in hydration status during dehydration and rehydration.The normal plasma osmolarity is in the range of 280-300 mOs/kg.lasma osmolarity: The osmolarity of blood plasma, which is a measure of the hydration status. The plasma osmolarity is sensitive to changes in hydration status during dehydration and rehydration.