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The acute effects of marijuana (THC and other associated cannabinoids) include: 1  Euphoria. 2  Dry mouth. 3  Reddening of eyes. 4  Decrease in intra-ocular pressure. 5  Muscle relaxation. 6  Depersonalization. 7  Increased appetite. 8  Effects on attention. 9  Altered visuospatial reasoning. 10  Altered time sense. 11  Lethargy. 12  Drowsiness. 13  Occasional anxiety and paranoia.
While these and other effects seem harmless, they can take a toll on the body. 1  Increased heart rate. When someone uses marijuana, heart rateânormally 70 to 80 beats per minuteâmay increase by 20 to 50 beats per minute or, in some cases, even double. 2  Respiratory (lung and breathing) problems.