It became clear that, in order to fully implement the intent of the streamlining initiative, CSAVR, its member state agencies, and RSA needed to agree on some fundamental changes in policy and practice. To accomplish its goal, the RSA provides its members with leadership and service.
Methadone was introduced into the United States in 1947 by Eli Lilly and Company as an analgesic under the trade name Dolophine, which is now registered to Roxane Laboratories. Since then, it has been best known for its use in treating opioid dependence.
Methadone maintenance has been used to treat opioid dependence for more than 45 years (invented in 1937). Therapeutic dosing is contingent upon individual patient needs, and the therapeutic dosage range is generally between 25 to 150 mg. Such a dose would not be tolerated by an opioid-naive individual.