The half-life of the ketorolac tromethamine S-enantiomer was approximately 2.5 hours (SD Â± 0.4) compared with 5 hours (SD Â± 1.7) for the R-enantiomer. In other studies, the half-life for the racemate has been reported to lie within the range of 5 to 6 hours.
Proton pump inhibitors (PPIs) are a group of drugs whose main action is a pronounced and long-lasting reduction of gastric acid production. Within the class of medications, there is no clear evidence that one agent works better than another. They are the most potent inhibitors of acid secretion available.
Pantoprazole and Omeprazole are two drugs coming under the drug class category of proton pump inhibitors. Proton pumps are situated in mitochondrial membranes, which mean they are in almost all cells. The importance of these drugs is that they selectively inhibit proton pumps in the stomach lining.