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Osmolality of blood increases with dehydration and decreases with overhydration. In normal people, increased osmolarity in the blood will stimulate secretion of antidiuretic hormone (ADH). This will result in increased water reabsorption, more concentrated urine, and less concentrated blood plasma.
Three termsâhypotonic, isotonic, and hypertonicâare used to relate the osmolarity of a cell to the osmolarity of the extracellular fluid that contains the cells . In a hypotonic situation, the extracellular fluid has lower osmolarity than the fluid inside the cell, and water enters the cell.