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1 Breathing problems. 2  Marijuana smoke irritates the lungs, and frequent marijuana smokers can have the same breathing problems that tobacco smokers have. 3  These problems include daily cough and phlegm, more frequent lung illness, and a higher risk of lung infections.
Long-term detrimental effects of marijuana may include: 1  Respiratory problems: Marijuana smoke has many of the same irritating and lung-damaging properties as tobacco smoke. 2  Long-term users may develop a chronic cough and are at higher risk of lung infections.