Darren's mother is from Cebu in the Philippines, and has Filipino, Chinese, and Spanish ancestry. Darren's father is from Pittsburgh, Pennsylvania, and has English, and some German and Northern Irish, ancestry.
Description. While dwarfism is sometimes used to describe achondroplasia, a condition characterized by short stature and disproportionately short arms and legs, it is also used more broadly to refer to a variety of conditions resulting in unusually short stature in both children and adults.
Achondroplasia is caused by a gain-in-function mutation in the gene that encodes the FGFR3. In the growth plate, the natural function of FGFR3 is to reduce the growth pace, acting in concert with several other agents, such as CNP.chondroplasia is caused by a gain-in-function mutation in the gene that encodes the FGFR3. In the growth plate, the natural function of FGFR3 is to reduce the growth pace, acting in concert with several other agents, such as CNP.