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The two are often believed to be interchangeable, but the main difference is that retinol is eventually converted into retinoic acid. Retinol is a natural form of vitamin A, while Retin-A is derived from retinoic acid, a synthetic derivative of vitamin A, and considered pharmaceutical.
retin-a/retin-a micro vs. renova Q: How is RENOVA different from RETIN-AÂ® (tretinoin) and RETIN-AÂ® MICROÂ® (tretinoin gel) microsphere, 0.1%? A: RENOVA contains the same active ingredient as RETIN-A and RETIN-A MICRO. Tretinoin is a Vitamin A derivative like the one naturally occurring in your body (Vitamin A is an essential nutrient found in yellow and orange vegetables such as carrots and yams).