Leaf spot first appears in rainy or humid weather as the plants are growing. They look like small brown spots with a water-soaked margin surrounded by a yellow halo usually on the upper halves of the iris leaves.
Two, caffeine enhances the sensation and contractility of the bladder. Another way caffeine can affect prostate health is through its ability to irritate the bladder because it is a theoxanthine, a family of drugs that includes theobromine (found in chocolate) and theophylline (found in tea). Theophylline also stimulates and irritates the bladder.
Research Showing Harmful Effects of Caffeine. 1  More than 4 cups of coffee linked to early death. A Mayo Clinic partnered study found that men who drank more than four 8 fl.oz. cups of coffee had a 21% increase in all-cause mortality. 2  Caffeine consumption may raise blood pressure.