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1 Breathing problems. 2  Marijuana smoke irritates the lungs, and frequent marijuana smokers can have the same breathing problems that tobacco smokers have. 3  These problems include daily cough and phlegm, more frequent lung illness, and a higher risk of lung infections.
1 Marijuana use affects dopamine; a neurotransmitter involved in the brain's pleasure producing or reward mechanism, which helps explain its potential for dependency. 2  Memory impairment. 3  Marijuana use can negatively affect short-term memory, especially memories formed while a person was high. 4  Heart and lungs.