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Symptoms of mononucleosis generally resemble those of the flu and include fever, sore throat, and swollen lymph glands. Sometimes, a swollen spleen or liver involvement may develop. These symptoms usually last for more than two days and may appear slowly.
The most common symptoms of mononucleosis are fever, sore throat, swollen glands (lymph nodes), and fatigue. Symptoms usually develop between four to six weeks after exposure to the EBV. Other signs and symptoms of mononucleosis may include the following: 1  headache, 2  rash, 3  malaise,  loss of appetite,