transthyretin amyloidosis-caused by mutations in the TTR gene. More than 100 mutations in the TTR gene have been found to cause transthyretin amyloidosis. Nearly all of these mutations change one protein building block (amino acid) in the transthyretin protein.
Statins deplete your body of CoQ10, which can have devastating results. If you take statin drugs without taking CoQ10, your health is at serious risk. If you have symptoms of statin damage, such as muscle pain, take anywhere from 200 to 500 mg of CoQ10 or ubiquinol, which is the reduced form.
Whether you need to be on a statin depends on your cholesterol level, along with your other risk factors for cardiovascular disease. Most people should try to keep their total cholesterol level below 200 milligrams per deciliter (mg/dL) (6.22 millimoles per liter, or mmol/L).f the risk is very low, there is probably no need for statins, unless the LDL is above 190 mg/dL (4.9 mmol/L). If the risk is very high â for example, someone who has had a heart attack in the past â the person may benefit from statins, even if his or her cholesterol is not elevated.