Well, that is psychological. Even the most diehard DOTA fan would agree that they can do things in a more efficient way. This would free up a lot of time, in many cases, they can achieve the same objectives with less time. This is why DOTA coaching is on the range.
Calcium deposits. Late in the disease, particularly if you've had the disease for a long time, deposits of calcium can occur in ... Raynaud's phenomenon. This is a condition in which your fingers, toes, cheeks, nose and ears initially turn pale when exposed to cold temperatures.
Calcium deposits can occur pretty much anywhere in the body, generally overlying a bony surface, such as, in your case, the wrist or your collarbone. Although a common assumption is that the calcium deposits much be related to getting too much calcium in your diet, this is actually not the case.