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AST (aspartate aminotransferase) is an enzyme found in high amounts in liver, heart, and muscle cells. It is also found in lesser amounts in other tissues. This article discusses the test to measure the amount of AST in the blood.
Why It Is Done. An aspartate aminotransferase (AST) test is done to: 1  Check for liver damage. 2  Help identify liver disease, especially hepatitis and cirrhosis. 3  Liver disease may produce symptoms such as pain in the upper abdomen, nausea, vomiting, and sometimes jaundice. 4  Check on the success of treatment for liver disease.