The Saskatchewan death rate, long in the 7.5â8.5/1,000 range, increased to 9.2 in 2001, perhaps to some extent due to the âbaby boomâ generation of the 1950s now reaching retirement age, but mostly due to a significant expansion of older-aged population.
Differentiation is an operation that allows us to find a function that outputs the rate of change of one variable with respect to another variable. Informally, we may suppose that we're tracking the position of a car on a two-lane road with no passing lanes.
Cell differentiation refers to the normal process by which a less specialized cell goes through development and maturation in order to become more distinct in terms of form and function. It is the process in which a cell changes into another cell type. During cell differentiation, the changes may include cell shape, cell size, membrane potential, metabolic activities, and responsiveness. These changes are brought about by modifications in gene expressions. An example of cell differentiation is the development of a single-celled zygote into a multicellular embryo that further develops into a more complex multisystem of distinct cell types of a fetus. The cell size, shape, polarity, metabolism and responsiveness to signals change dramatically such that a less specialized cell becomes more specialized and acquires a more specific role.