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The acute effects of marijuana (THC and other associated cannabinoids) include: 1  Euphoria. 2  Dry mouth. 3  Reddening of eyes. 4  Decrease in intra-ocular pressure. 5  Muscle relaxation. 6  Depersonalization. 7  Increased appetite. 8  Effects on attention. 9  Altered visuospatial reasoning. 10  Altered time sense. 11  Lethargy. 12  Drowsiness. 13  Occasional anxiety and paranoia.
How marijuana affects the mind. Marijuana reaches the same pleasure centers in the brain that are targeted by heroin, cocaine and alcohol. Depending on the quantity, quality and method of consumption, marijuana can produce a feeling of euphoria â or high â by stimulating brain cells to release the chemical dopamine.