Mikaela Shiffrin wins parallel slalom city event in Oslo. Shiffrin matches her childhood idol, Marlies Schild, with her 37th World Cup victory.
It stores and produces hormones that affect the function of virtually every organ in our bodies. Thyroid hormone (Triiodothyronine or T3) regulates our metabolic rate and is associated with modest changes in body weight and energy levels.
Thyroid hormones are important players in the homeostasis of several tissue including skeletal muscle and their genomic action mostly depend on the tissue T3 bioavailability and on the distribution of the thyroid receptor isoforms which act as transcription factors and are modulated by T3.ven the mechanisms are not fully understood, the myopathy secondary to thyroid dysfunctions outlines the importance of THs and their signaling in skeletal muscle phenotypes and functions. The genomic actions of T3 are mediated by thyroid hormone nuclear receptors (TRs), which act regulating gene transcription [10].