Moving toward continuous production with SIMATIC SIPAT. The technological basis for continuous manufacturing is the use of Process Analytical Technology (PAT). Previously, it was virtually impossible to determine the clinical efficacy of an active ingredient online.
Benzene is a component of products derived from coal and petroleum and is found in gasoline and other fuels. Benzene is used in the manufacture of plastics, detergents, pesticides, and other chemicals. With exposures from less than five years to more than 30 years, individuals have developed, and died from, leukemia. Long-term exposure may affect bone marrow and blood production. Short-term exposure to high levels of benzene can cause drowsiness, dizziness, unconsciousness, and death.
Human exposure to benzene has been associated with a range of acute and long-term adverse health effects and diseases, including cancer and aplastic anaemia. Exposure can occur occupationally and domestically as a result of the ubiquitous use of benzene-containing petroleum products, including motor fuels and solvents. ï· Benzene is a moderate eye irritant and a skin irritant. Benzene is a well-established cause of cancer in humans. Chronic exposure to benzene can reduce the production of both red and white blood. cells from bone marrow in humans, resulting in aplastic anaemia.