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The treatment goals for hypothyroidism are to reverse clinical progression and correct metabolic derangements, as evidenced by normal blood levels of thyroid-stimulating hormone (TSH) and free thyroxine (T4). Thyroid hormone is administered to supplement or replace endogenous production.
Testosterone replacement therapy (TRT) is the recommended treatment for male hypogonadism. It is normally given as a topical gel, transdermal patch, or by injection. Oral forms of testosterone are not used due to the high risk of side effects, such as upset stomach. TRT can eliminate many, if not all, of the signs and symptoms of male hypogonadism.