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The two are often believed to be interchangeable, but the main difference is that retinol is eventually converted into retinoic acid. Retinol is a natural form of vitamin A, while Retin-A is derived from retinoic acid, a synthetic derivative of vitamin A, and considered pharmaceutical.
Ask a question. Please tell me the difference between Retin A and Differin. Allison35. Hello, I am hoping someone can help tell the difference between these produtcs. Last yr I went on Retin A 0.05% and although it took awhile I had pretty good results, skin was smoothe and had a nice glow and clear as well.