States with the highest per student expenditures were: 1  Vermont ($19,752), 2  New York ($19,523), 3  New Jersey ($19,291), 4  Alaska ($18,192),and. 5  Rhode Island ($17,666).
1 Glucagon binds its receptor in the plasma membrane of target cells (e.g. hepatocytes). 2  Bound receptor interacts with and, through a set of G proteins, turns on adenylate cyclase, which is also an integral membrane protein.
Circulating insulin binds to specific insulin receptors located on the cell membrane of tissue cells throughout the body. Upon binding, a signal is sent to the nucleus of the cell, instructing it to transport glucose channels to the cell surface.