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However, general guidelines are as follows: 1  For a headache or muscle ache, take 325 mg of aspirin every 4-6 hours. 2  To prevent a heart attack, take two low-dose (81 mg) aspirin every day if youâre at risk or over 40.
Aspirin not recommended for: Men younger than 45, and women younger than 55. Anyone 80 and older. Aspirin for heart attack prevention My personal opinion is that aspirin, in a dosage of 81 mg 2 or 3 times a week, should provide enough benefits and at the same time minimize the risk for stomach ulcer or bleeding.There is no need to take higher dosages for cardiovascular health.spirin for heart attack prevention My personal opinion is that aspirin, in a dosage of 81 mg 2 or 3 times a week, should provide enough benefits and at the same time minimize the risk for stomach ulcer or bleeding.