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some of these medicines that may lead to prednisone drug interactions include barbiturates including amobarbital amytal butalbital fioricet fiorinal pentobarbital nembutalphenobarbital luminal secobarbital seconal certain diuretics such as bumetanide bumexrednisone can potentially interact with certain other medications some of these medicines that may lead to prednisone drug interactions include barbiturates including amobarbital amytal butalbital fioricet fiorinal pentobarbital nembutal phenobarbital luminal secobarbital seconal
To understand how prednisone interacts with other drugs, it is important to know how it is metabolized by the body. Basically, prednisone works by altering the immune and inflammatory responses of the body. After administering oral prednisone tablet, the gastrointestinal membrane readily absorbs the medication. It then takes effect in a matter of 1 to 2 hours. During the peak effect, the drug compounds breakdown and circulate through the system. It then binds with the plasma protein and is circulated through the body. When it gets to the liver, prednisone is metabolized to produce its active form â prednisolone.