The most common immediate adverse reactions to transfusion are fever, chills and urticaria. The most potentially significant reactions include acute and delayed haemolytic transfusion reactions and bacterial contamination of blood products.
Penicillin allergy is an overreaction by your immune system to penicillin and other antibiotics in the beta-lactam family and closely related antibiotics. Doxycycline belongs to a class of drugs called Tetracyclines. Tetracyclines are unrelated to penicillins and therefore safe to take in hypersensitive patients. Other unrelated antibiotics include quinolones (e.g. ciprofloxacin), macrolides (e.g. clarithromycin), aminoglycosides (e.g. gentamicin) and glycopeptides (e.g. vancomycin).
Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline, and is available as doxycycline for oral suspension USP (doxycycline monohydrate) for oral administration. with a molecular formula of C22H24N2O8.H2O and a molecular weight of 462.46.