Make sure that your cuts are as accurate as possible. If you need to trim areas, you can simply run the knife along the edge. Hold the knife so that the blade bites slightly into the edge. This can be a tedious process so try to get it right the first time.
When insulin binds to the receptor, it is thought to cause a change in shape that is propagated inside the cell, activating the tyrosine kinases. The details are still a mystery and an area of active research.
The binding of insulin to its receptor on liver cells leads to increased synthesis of glycogen and inhibition of glucose production by liver cells. Over time following a meal, glucose levels will fall, and once a certain threshold is reached, low glucose levels stimulate glucagon release from pancreatic alpha cells.