Going into the ceremony (which airs at 8:30 p.m. ET on ABC), Martin Scorseseâs Howard Hughes film bio, The Aviator, leads the race with 11 nominations, though most bets are on Clint Eastwoodâs somber boxing drama Million Dollar Baby to win the lionâs share of Oscar gold.
The prostate specific antigen is often used as a biological marker or a tumor marker for detecting prostate cancer. However elevated levels of PSA are not indicative of prostate cancer and additional investigations are required for further diagnosis. There are several factors that may be responsible for elevated levels of PSA in the blood, 1  Benign Enlargement of the Prostate or BPH is a condition which affects older men.
In order to increase the efficacy of serum PSA interpretation, a number of performance variables are used clinically. These include age-adjusted PSA, density, velocity, and the free-to-complexed PSA ratio. Age Adjusted PSA: Since PSA normally rises with age, age-adjusted thresholds have been described. Benign growth of the prostate that normally occurs with age is the most common cause of PSA elevation. Roughly 70% of patients with an elevated PSA level between 4 and 10 will have a negative prostate biopsy. Conversely, there is no level of PSA at which you can guarantee a patient that they do not have cancer. Moreover, the absolute PSA level does not predict whether or not prostate cancer is harmful.