Signs and symptoms of heat exhaustion may develop suddenly or over time, especially with prolonged periods of exercise. Possible heat exhaustion signs and symptoms include: Cool, moist skin with goose bumps when in the heat. Heavy sweating. Faintness. Dizziness. Fatigue.
Abstract. Oral submucous fibrosis (OSMF) is an insidious chronic disease affecting any part of the oral cavity and sometimes the pharynx with epithelial atrophy leading to stiffness of the oral mucosa, causing trismus and inability to eat.SMF is poorly understood and unsatisfactorily treated disease. However, a more serious complication of this disease is the risk of the development of oral carcinoma. The precancerous nature of OSMF has been observed with development of slowly growing squamous cell carcinoma in one-third of OSMF patients [ 2, 7 ].
Myelofibrosis (MF). 1  Is a rare bone marrow cancer. 2  Is a type of chronic leukemia and can occur on its own (primary myelofibrosis) or as a result of another bone marrow disorder. It is one of a related group of blood cancers known as âmyeloproliferative neoplasms (MPNs)â in which bone marrow cells that produce the blood cells develop and function abnormally. 2  The resulting fibrous scar tissue formation leads to severe anemia, weakness, fatigue and an enlarged spleen and liver.