Elements of Latin, French and other languages became incorporated into English through the Middle Ages, and name spellings changed even among the literate. The variations of the surname Fish include Fish, Fishe and others.
The two basic tissues of which the skin is composed are dense connective tissue, which makes up the dermis, and __1__, which forms the epidermis. Most cells of the epidermis are __2__. The protein __3__ makes the dermis tough and leather like.
The skin (integument) and its derivatives (adnexa) comprise the largest organ in the body. Skin is composed of two layers: (1) the ectodermally derived surface layer called the epidermis and (2) the underlying mesodermally derived connective tissue layer which is called the dermis. The epidermis is a stratified squamous epithelium with a different number of cell layers in different areas of skin.