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The zygomaticus major is a muscle of the human body. It is a muscle of facial expression which draws the angle of the mouth superiorly and posteriorly (smile).he zygomaticus major is a muscle of the human body. It is a muscle of facial expression which draws the angle of the mouth superiorly and posteriorly (smile).
Zygomaticus pain can radiate into the eye area. Photo Credit Jupiterimages/Goodshoot/Getty Images. The zygomaticus muscles make it possible for you to speak, chew and use your face to express emotions. You can injure these muscles by overuse or trauma.Because they are connected to the eye socket and the jawbone, injuries, irritation or disease in these areas can affect the zygomaticus as well.Some types of zygomaticus pain can heal with rest, but chronic pain may indicate a serious condition.ygomaticus pain can radiate into the eye area. Photo Credit Jupiterimages/Goodshoot/Getty Images. The zygomaticus muscles make it possible for you to speak, chew and use your face to express emotions. You can injure these muscles by overuse or trauma.