Offside in open play Offside is quite a complicated rule of rugby union, so make sure you pay attention and listen to what the referee is saying. If a player is in front of a team-mate in possession of the ball, or in front of their team-mate who last played the ball, they will be offside if: 1  They are actively trying to play the ball. 2  Do not retire within 10m of an opponent who is waiting for the ball.
FRAMESHIFT MUTATION. This type of mutation occurs when the addition or loss of DNA bases changes a geneÂ´s reading frame. Extra base pairs may be added (insertions) or removed (deletions) from the DNA of a gene. The number can range from one to thousands. Collectively, these mutations are called indels.
A missense mutation occurs when one DNA nucleotide is changed so that a different amino acid is inserted into a protein. Nucleotides are the repeating units of a DNA sequence. There are four nucleotides, each with different nitrogenous bases: thymine (T), adenine (A), guanine (G), and cytosine (C).