The most common immediate adverse reactions to transfusion are fever, chills and urticaria. The most potentially significant reactions include acute and delayed haemolytic transfusion reactions and bacterial contamination of blood products.
Penicillin allergy is an overreaction by your immune system to penicillin and other antibiotics in the beta-lactam family and closely related antibiotics. Doxycycline belongs to a class of drugs called Tetracyclines. Tetracyclines are unrelated to penicillins and therefore safe to take in hypersensitive patients. Other unrelated antibiotics include quinolones (e.g. ciprofloxacin), macrolides (e.g. clarithromycin), aminoglycosides (e.g. gentamicin) and glycopeptides (e.g. vancomycin).
Doxycycline is a broad-spectrum antibiotic of the tetracycline class. Like other agents of this class it kills bacteria and protozoa by inhibiting protein production. Doxycycline came into use in 1967.t is also useful for the treatment of malaria when used with quinine and for the prevention of malaria. Doxycycline can be used either by mouth or intravenously. Common side effects include diarrhea, nausea, vomiting, a red rash, and an increased risk of a sunburn.