Darren's mother is from Cebu in the Philippines, and has Filipino, Chinese, and Spanish ancestry. Darren's father is from Pittsburgh, Pennsylvania, and has English, and some German and Northern Irish, ancestry.
Description. While dwarfism is sometimes used to describe achondroplasia, a condition characterized by short stature and disproportionately short arms and legs, it is also used more broadly to refer to a variety of conditions resulting in unusually short stature in both children and adults.
Genetics. 1  Achondroplasia is a single gene disorder caused by mutations in the FGFR3 gene on chromosome 4. 2  Two different mutations in the FGFR3 gene cause more than 99 per cent of cases of achondroplasia. 3  It is a dominant genetic disease so only one copy of the FGFR3 gene needs to be mutated for symptoms to develop.chondroplasia is a genetic disorder affecting bone development that results in short-limb dwarfism. 1  Achondroplasia is the most common form of short-limb dwarfism, a disorder in which bone tissue does not develop properly, especially the long bones of the arms and legs.