It's home to two colleges, Keene State College and Antioch University New England, and the annual Keene Music Festival, when the hippie-music vibe takes over most of this town of 24,000. For years, it was also home to the Pumpkin Festival, which set two world records for most simultaneously lit jack-o'-lanterns.
We begin our history of vaccines and immunization with the story of Edward Jenner, a country doctor living in Berkeley (Gloucestershire), England, who in 1796 performed the worldâs first vaccination. 4 Taking pus from a cowpox lesion on a milkmaidâs hand, Jenner inoculated an eight-year-old boy, James Phipps.his paper explores the history of vaccines and immunization, beginning with Edward Jennerâs creation of the worldâs first vaccine for smallpox in the 1790s.
Gun Timeline. Historical timeline of the development of modern weapons starting at 1364 with the first recorded use of a firearm and ending in 1892 with the introduction of automatic handguns. 1364 - First recorded use of a firearm. 1380 - Hand guns are known across Europe. 1400s - The matchlock gun appears. Before the matchlock, guns were fired by holding a burning wick to a touch hole in the barrel igniting the powder inside. A shooter uses one hand for firing, and a prop to steady the gun.The first device, or lock, for mechanically firing a gun is the matchlock.