Generalized anxiety disorder symptoms include: 1  Restlessness or feeling wound-up or on edge. 2  Being easily fatigued. 3  Difficulty concentrating or having their minds go blank. 4  Irritability. Muscle tension.  Difficulty controlling the 1  worry. Sleep problems (difficulty falling or staying asleep or restless, unsatisfying  sleep)
Protein Properties: Binding Sites [edit]. A binding site is a position on a protein that binds to an incoming molecule that is smaller in size comparatively, called ligand. In proteins, binding sites are small pockets on the tertiary structure where ligands bind to it using weak forces (non-covalent bonding).
Chemical structures of ATP and anti-angiogenic tyrosine kinase inhibitors. a Chemical structure of ATP. ATP consists of an adenine ring, a ribose sugar, and three phosphate groups. The adenine ring, which forms hydrogen bonds with the ATP-binding site of its target kinase, is encircled in this figure.