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About 45 people a day, more than 16,600 people a year, die from overdoses of the drugs, including methadone, morphine, and oxycodone (OxyContin) and hydrocodone combined with acetaminophen (Lortab and Vicodin). And for every death, more than 30 others are admitted to the emergency room.
Best Answer: Generally the pills you mentioned cause death by one of two mechanisms 1. Tylenol/Excedrin-These products contain Acetaminophen. Too much acetaminophen causes a depletion of glutathione in the liver causing oxidative damage and eventual necrosis of hepatocytes. The short version is it kills your liver.&#39;m just curious-not suicidal so don&#39;t worry, but when you overdose on pills, such as excedrin, advil, tylenol, does it hurt, or do you just pass out and die peacefully?