Lyme disease is diagnosed clinically based on symptoms, objective physical findings (such as EM, facial palsy, or arthritis), or a history of possible exposure to infected ticks, as well as serological blood tests. The EM rash is not always a bull's eye, i.e., it can be solid red.
Rule of Thumb for Changing Filters. The rule we have followed for 18 years in the filtration industry is to change filters every 6 to 12 months. Six months is almost always optimum, especially in commercial/office settings, and twelve months is as long as you want to go no matter what.
Replacement refrigerator water filters range in cost, but on average, to change your filter two times a year would roughly cost $70-$80. Furthermore, by using two water filters per year, a refrigerator can filter about 3,000 bottles of water.