This is especially important for patients on multiple medications: For statins metabolized by P450 3A4 (CYP3A4) (simvastatin, lovastatin, atorvastatin), concomitant administration of medications that inhibit the CYP3A4 pathways (protease inhibitors, cyclosporine, amiodarone, fibrates) is problematic. The result is increased statin levels and increased risk for muscle tissue injury. On the other hand, fluvastatin and rosuvastatin (metabolized by CYP2C9) and pravastatin (metabolized by the kidneys) are considered to be safer statin choices for patients on multiple medications. 1 of 4.
Stranger anxiety is a typical part of the developmental sequence that most children experience. It can occur even if the child is with a caregiver or another person they trust. It peaks from 6 to 12 months but may recur afterwards until the age of 24 months. As a child gets older, stranger anxiety can be a problem as they begin to socialize. Children may become hesitant to play with unfamiliar children.
Basically, if your child is age seven or younger, they should never be left alone. Kids ages 8-10 can be alone briefly, and ages 10-13 for longer periods, provided there is back-up supervision. Babysitters should be at least 12-13 years old, and can babysit for longer periods as they grow older. Get recommendations from friends. 2  Trade childcare with friends who have kids. 3  Do not hire a sitter under age 12. 4  Watch your childâs reaction when you tell them a sitter they know is coming, and listen to what your child says about the sitter afterward.