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The most common types of medicines that doctors use to treat acne include: 1  Benzoyl peroxide, such as Brevoxyl or Triaz. 2  Salicylic acid, such as Propa pH or Stridex. 3  Topical and oral antibiotics, such as clindamycin, doxycycline, erythromycin, and tetracycline.
Clindamycin is a lincosamide antibiotic. It is usually used to treat infections with anaerobic bacteria but can also be used to treat some protozoal diseases, such as malaria. It is a common topical treatment for acne, and can be useful against some methicillin-resistant Staphylococcus aureus (MRSA) infections.hese antibiotics exert their activity by binding to bacterial ribosomes and preventing the initiation of protein synthesis. Streptomycin binds to 30S subunit of the bacterial ribosome, specifically to the S12 protein which is involved in the initiation of protein synthesis.