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Causes of yellow eyes in children and adults. Yellow eyes, as well as yellowing of the skin, occur in children and adults when bilirubin builds up due to serious diseases and conditions that cause liver damage or dysfunction, or block the bile ducts.
Liver or biliary-system causes of yellow eyes include: Bile duct narrowing or obstruction (due to gallstones or pancreatitis) Cancer including that of the liver and pancreas. Cirrhosis (liver scarring due to a variety of liver diseases) Drug-induced cholestasis (slowing of bile flow due to medications)