Generalized anxiety disorder symptoms include: 1  Restlessness or feeling wound-up or on edge. 2  Being easily fatigued. 3  Difficulty concentrating or having their minds go blank. 4  Irritability. Muscle tension.  Difficulty controlling the 1  worry. Sleep problems (difficulty falling or staying asleep or restless, unsatisfying  sleep)
Protein Properties: Binding Sites [edit]. A binding site is a position on a protein that binds to an incoming molecule that is smaller in size comparatively, called ligand. In proteins, binding sites are small pockets on the tertiary structure where ligands bind to it using weak forces (non-covalent bonding).
Enzymes operate by binding to a substrate or substrates temporarily, lowering the activation energy necessary for a reaction to take place. The catalytic (active) site is the portion of the enzyme where substrate binding occurs. Each enzyme is specific for one or more substrate types. Two different theories about how enzyme-substrate binding exist. In the induced-fit (key and lock) model (a), the active site of an enzyme has a shape specific to the substrate.