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The most common types of medicines that doctors use to treat acne include: 1  Benzoyl peroxide, such as Brevoxyl or Triaz. 2  Salicylic acid, such as Propa pH or Stridex. 3  Topical and oral antibiotics, such as clindamycin, doxycycline, erythromycin, and tetracycline.
If over-the-counter treatments like benzoyl peroxide and salicylic acid aren't improving acne antibiotics may be suggested by your doctor. Clindamycin and erythromycin are the most commonly prescribed antibiotics for topical acne treatment.