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Severe cases of renal failure may require a kidney transplant. Summary. Rhabdomyolysis is a potentially lethal syndrome with a broad spectrum of causes and symptoms. The clinical symptoms vary widely from myalgia to severe muscle weakness with involvement of other organ symptoms.
Rhabdomyolysis. Rhabdomyolysis is a condition in which damaged skeletal muscle tissue breaks down rapidly. Breakdown products of damaged muscle cells are released into the bloodstream. Some of these, such as the protein myoglobin, are harmful to the kidneys and may lead to kidney failure.PubMed Health Glossary.bout Rhabdomyolysis. Rhabdomyolysis is an extremely rare but serious side effect where muscle tissue gradually breaks down in certain muscles. This can lead to permanent paralysis, and the breakdown products can cause serious kidney damage.