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Severe cases of renal failure may require a kidney transplant. Summary. Rhabdomyolysis is a potentially lethal syndrome with a broad spectrum of causes and symptoms. The clinical symptoms vary widely from myalgia to severe muscle weakness with involvement of other organ symptoms.
rhabdomyolysis, the clinical and biological consequences of this syndrome and to provide an appraisal of the current data available in order to facilitate the prevention, early diagnosis and prompt management of this condition. Keywords Creatine kinase, rhabdomyolysis, muscle weakness, myoglobin, myoglobinuria introduCtion Rhabdomyolysis is a potentially life-threatening syndrome characterised by the breakdown of skeletal muscle resulting in the subsequent release of intracellular contents into the circulatory system. These cell contents include enzymes such as creatine kinase (CK), glutamic oxalacetic transaminase, lactate dehydrogenase, aldolase, the haeme pigment myoglobin, electrolytes such as potassium review rhabdomyolysis: a review of the literature F.Y. Khan