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Yes my sister is 23 and just recently noticed that one pupil is larger than the other. She just recently saw the eye doctor and he didnt notice it. She has been having headaches along with the weird pupils. She doesnt complain of sensitivity she just gets headaches.
The only thing we as clinicians worry about with respect to pupil size is making sure that the two pupils are equal in size and that they are reactive to light. If they are equal in size and reactive to light, this means that the neurological network in the brain that controls the pupils is working properly. As long as someone can see fine, I would not be worried about pupils that are smaller than average.