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By Mayo Clinic Staff. Hand numbness is usually caused by damage, irritation or compression of one of the nerves or a branch of one of the nerves in your arm and wrist. Diseases affecting the peripheral nerves, such as diabetes, also can cause numbness, although with diabetes similar symptoms usually occur first in your feet.
Numb hands and tingling in the hands can be caused by diseases of the central nervous system. Multiple sclerosis, stroke, and other disorders of the brain and spinal cord may sometimes cause numbness in the forearm and hand.Other diseases can affect the nerves in the upper limb, causing numbness, tingling, burning.ESCRIPTION. Although carpal tunnel syndrome is common, it is not the only cause of numbness, tingling, and pain in the forearm and hand. CAUSES. Although carpal tunnel syndrome is common, it is not the only cause of numbness, tingling, and pain in the forearm and hand.