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The duodenum is the first part of the small intestine. It is located between the stomach and the middle part of the small intestine, or jejunum. After foods mix with stomach acid, they move into the duodenum, where they mix with bile from the gallbladder and digestive juices from the pancreas.
The duodenum is the first of the three parts of the small intestine and continues from the pylorus of the stomach. It is the shortest part of the small intestine, measuring approximately 25 centimeters in length and is also the most important site of digestion as the pancreatic enzymes and bile empty into the duodenum.