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The most common types of medicines that doctors use to treat acne include: 1  Benzoyl peroxide, such as Brevoxyl or Triaz. 2  Salicylic acid, such as Propa pH or Stridex. 3  Topical and oral antibiotics, such as clindamycin, doxycycline, erythromycin, and tetracycline.
1 Some antibiotics kill acne on contact, but others just cause them to go dormant. 2  Antibiotics are available as pills you take by mouth and as gels, lotions, creams, and serums you put on your face.  The antibiotic you used 10 years ago may no longer be effective, as acne bacteria develop antibiotic resistance.