DEA 3.0 System: Dogs may have a DEA 3 system of blood type, if their blood has two antigens, DEA 3.0 and DEA Null. This is a rare type of blood and occurs in only in 5 â 6% of dogs. The most common breed with a DEA 3.0 positive type blood are grey hounds, in which 23% of all population is considered positive. If the dog is incompatible for this blood type and is transfused, erythrocytes or blood cells are usually replaced in 3 â 5 days, automatically.
Executive Summary. 1  The bloodâbrain barrier (BBB) is a significant obstacle to therapeutic delivery for CNS disorders. Among various strategies, nanobiotechnology plays an important role in facilitating drug delivery across the BBB. 2  Desirable characteristics of the ideal method of therapeutic delivery across the BBB are described in this article.
The bloodâbrain barrier is formed by brain endothelial cells, which are connected by tight junctions with an extremely high electrical resistivity of at least 0.1 Ïâm.he BBB is distinct from the quite similar bloodâcerebrospinal-fluid barrier, which is a function of the choroidal cells of the choroid plexus, and from the bloodâretinal barrier, which can be considered a part of the whole realm of such barriers. Several areas of the human brain are not on the brain side of the BBB.