Generalized anxiety disorder symptoms include: 1  Restlessness or feeling wound-up or on edge. 2  Being easily fatigued. 3  Difficulty concentrating or having their minds go blank. 4  Irritability. Muscle tension.  Difficulty controlling the 1  worry. Sleep problems (difficulty falling or staying asleep or restless, unsatisfying  sleep)
Protein Properties: Binding Sites [edit]. A binding site is a position on a protein that binds to an incoming molecule that is smaller in size comparatively, called ligand. In proteins, binding sites are small pockets on the tertiary structure where ligands bind to it using weak forces (non-covalent bonding).
For an enzyme to work it must bind to a specific substrate molecule, using a part of the enzyme molecule called the active site. To do this, the enzyme's active site and the s â¦ ubstrate must have matching (complementary) shapes.The shape of an enzyme molecule depends on the exact way in which the molecule folds up.When enzymes are heated the weak bonds which hold the molecules in their precise shape are broken, and the enzyme molecule unwinds into a random shape. It can no longer bind with its substrate so it no longer has any activity.This unwinding of a protein molecule is called denaturation.hen enzymes are heated the weak bonds which hold the molecules in their precise shape are broken, and the enzyme molecule unwinds into a random shape. It can no longer bind with its substrate so it no longer has any activity. This unwinding of a protein molecule is called denaturation.