DEA 3.0 System: Dogs may have a DEA 3 system of blood type, if their blood has two antigens, DEA 3.0 and DEA Null. This is a rare type of blood and occurs in only in 5 â 6% of dogs. The most common breed with a DEA 3.0 positive type blood are grey hounds, in which 23% of all population is considered positive. If the dog is incompatible for this blood type and is transfused, erythrocytes or blood cells are usually replaced in 3 â 5 days, automatically.
Executive Summary. 1  The bloodâbrain barrier (BBB) is a significant obstacle to therapeutic delivery for CNS disorders. Among various strategies, nanobiotechnology plays an important role in facilitating drug delivery across the BBB. 2  Desirable characteristics of the ideal method of therapeutic delivery across the BBB are described in this article.
The bloodâbrain barrier allows the passage of water, some gases, and lipid-soluble molecules by passive diffusion, as well as the selective transport of molecules such as glucose and amino acids that are crucial to neural function.he bloodâbrain barrier is composed of high-density cells restricting passage of substances from the bloodstream much more than do the endothelial cells in capillaries elsewhere in the body.