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Semen is made up of sperm (male cells for sexual reproduction) floating in a fluid called seminal plasma. Sperm, also called spermatozoa, are made by a man's testicles and mature (grow up) in the epididymis. The fluids in seminal plasma come from different glands in the man's body: the seminal vesicles, prostate and bulbourethral glands (also called the Cowper's glands).
The Testicular Factory. Sperm are produced in the male testicle (testis). The testis is filled with tiny coiled tubes (seminiferous tubules) through which sperm move as they are produced. Each seminiferous tubule is lined with sperm nurse cells (Sertoli cells) and sperm stem cells (Spermatagonia).