As in other autoimmune diseases such as lupus and rheumatoid arthritis, the bodyâs natural ability to attack invading viruses and bacteria goes haywire and mistakenly sees healthy body proteins as enemies. Redness, pain, heat and swelling signal that the immune system is on the warpath.
Formal Charge = [# valence electrons on neutral atom] â [(# lone electron pairs) + (Â½ # bonding electrons)] 1  Valence electrons = corresponds to the group number of the periodic table (for representative elements).  Lone Pairs = lone electrons sitting on the atom. Each electron counts as one and so a pair counts as two.
When determining the best Lewis structure (or predominant resonance structure) for a molecule, the structure is chosen such that the formal charge on each of the atoms is as close to zero as possible. The formal charge of any atom in a molecule can be calculated by the following equation: