Long-term muscle use requires the delivery of oxygen and glucose to the muscle fiber to allow aerobic respiration to occur, producing the ATP required for muscle contraction. If the respiratory or circulatory system cannot keep up with demand, then energy will be generated by the much less efficient anaerobic respiration.
Then, Nicaragua, as well as Costa Rica, El Salvador, Guatemala and Honduras formed the United Provinces of Central America, but that federation quickly dissolved, and Nicaragua became an independent republic in 1838.
Location and Geography. As the largest country in Central America with an area of 51,000 square miles (129,494 square kilometers), Nicaragua is about the size of New York State. The country is bounded by the Pacific Ocean and Caribbean Sea, with Honduras bordering it at the north and Costa Rica at the south.