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About 45 people a day, more than 16,600 people a year, die from overdoses of the drugs, including methadone, morphine, and oxycodone (OxyContin) and hydrocodone combined with acetaminophen (Lortab and Vicodin). And for every death, more than 30 others are admitted to the emergency room.
There are zero documented overdoses directly from LSD not only per year, but entirely. No one has ever died from LSD. It's a harmless drug physically. The only way LSD use would result in death would be as a result of a fatal decision the LSD use helped influence you to make.