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Acute diarrhea causes may include: 1  Antacids containing magnesium. 2  Antibiotic-associated diarrhea. 3  Blood pressure medications. 4  C. difficile. 5  Campylobacter infection. 6  Cancer medications. 7  Clostridium perfringens infection.
There are many different causes, depending on how long the diarrhea has lasted (see Table: Some Causes and Features of Diarrhea). The most common causes of acute diarrhea (lasting less than a week) are. Infection with viruses, bacteria, or parasites (gastroenteritisâsee Gastroenteritis)