Generalized anxiety disorder symptoms include: 1  Restlessness or feeling wound-up or on edge. 2  Being easily fatigued. 3  Difficulty concentrating or having their minds go blank. 4  Irritability. Muscle tension.  Difficulty controlling the 1  worry. Sleep problems (difficulty falling or staying asleep or restless, unsatisfying  sleep)
Protein Properties: Binding Sites [edit]. A binding site is a position on a protein that binds to an incoming molecule that is smaller in size comparatively, called ligand. In proteins, binding sites are small pockets on the tertiary structure where ligands bind to it using weak forces (non-covalent bonding).
The substrate binds to the enzyme at the active site. Two models have been proposed to explain this binding: the Lock and Key Model and the Induced Fit Model. Once the reaction is complete, the enzyme releases the product and is ready to bind with another substrate.