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By Amanda Gardner. HealthDay Reporter. WEDNESDAY, May 15 (HealthDay News) -- The U.S. Food and Drug Administration has approved new, lower-dose labeling for the popular sleep drug Ambien (zolpidem) in an effort to cut down on daytime drowsiness that could be a hazard while performing certain tasks such as driving.
The recommended adult dose of Ambien (zolpidem) is 10 mg as conventional tablets or spray or 12.5 mg as extended-release tablets. Alcohol has an additive effect with Ambien (zolpidem) and the two should not be combined. Ambien (zolpidem) should not be combined with other sedative drugs because of the additive effects. Sporanox (itraconazole) and ketoconazole may increase the blood concentration of Ambien (zolpidem). Rifadin, Rimactane (rifampin) may reduce the concentration of Ambien (zolpidem).