GeneCards Summary for CHAT Gene. CHAT (Choline O-Acetyltransferase) is a Protein Coding gene. Diseases associated with CHAT include Myasthenic Syndrome, Congenital, 6, Presynaptic and Congenital Myasthenic Syndrome With Episodic Apnea. Among its related pathways are Metabolism and Transmission across Chemical Synapses.
FREE subscriptions for doctors and students... click hereYou have 3 open access pages. Ludwig's angina is an acute cellulitis in the region of the submandibular gland. It is most commonly due to sepsis in the throat or mouth which migrates to the submandibular space.Occasionally, it may be the result of suppuration in the submandibular gland itself.1  it is necessary to consider the anatomy of the submandibular space in order to understand the pathophysiology of Ludwig's angina.t is most commonly due to sepsis in the throat or mouth which migrates to the submandibular space. Occasionally, it may be the result of suppuration in the submandibular gland itself. 1  it is necessary to consider the anatomy of the submandibular space in order to understand the pathophysiology of Ludwig's angina.
When too much cortisol is present in the body, it is called Cushingâs syndrome, regardless of the cause. Cortisol is made by the adrenal glands which are stimulated by ACTH, which is produced in pituitary gland. When the cause of the excess cortisol is excess ACTH made by a pituitary tumor, the condition is called Cushingâs disease. Rarely, excess ACTH can be produced by a tumor elsewhere in the body, which is referred to as ectopic production of ACTH. Another cause of Cushing's syndrome can be taking excess steroid medications. Finally, excess production of cortisol by an adrenal tumor can lead to Cushing's syndrome.