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The organ system in which the blood is pumped through the heart and circulates throughout the body through the blood vessels. Supplement. The cardiovascular system is a closed circulatory system seen in humans and other vertebrates. Its components include the heart, blood vessels, and blood.
The cardiovascular system has three main functions: Transports oxygen and nutrients to the body's cells and transports carbon dioxide and waste products from the body's cells. Protects the body from infection and loss of blood. Helps to regulate pH balance of the body, body temperature and the balance of fluid.