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Main article: Adrenal gland. The adrenal glands are located above the kidneys in humans and in front of the kidneys in other animals. The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol.
Adrenal glands produce hormones in response to signals from the hypothalamus and the pituitary gland in the brain. For example, for the adrenal gland to produce cortisol: The hypothalamus produces corticotropin-releasing hormone (CRH) that stimulates the pituitary gland to secrete adrenocorticotropin hormone (ACTH).