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The disease can occur at any age but is primarily a disease of adults. CML is characterized by a massive over-production of white blood cells. A normal white blood cell count ranges between 4,000 and 10,000; in contrast, patients with CML typically have white blood cell counts ranging from 100,000 to as high as 500,000.
An average normal range is between 3,500 and 10,500 white blood cells per microliter of blood (mcL). Infants are often born with much higher numbers of WBCs, which gradually even out as they age. According to the Mayo Clinic, these are the normal ranges of WBCs per microliter of blood by age: