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Pulmonary edema facts. 1  Pulmonary edema is typically caused by filling of alveoli in the lungs by fluid leaking out of the blood. 2  Pulmonary edema may be caused by a number of cardiac or non-cardiac conditions.  Breathing difficulty is the main manifestation of pulmonary edema.
1 Bacterial infections of the lung, such as pneumonia, can cause sections of the lungs to swell and edema to develop in that area. 2  Exposure to toxins. 3  Inhaled toxins, including chlorine and ammonia, as well as toxins from your body (inhaled vomit) can cause fluid in the lungs.