Remodeling reaction also involves DNA translocation, DNA twist and conformational change. As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton.
6' 4 (1.93 m) Actor, writer, and gourmet, Vincent Leonard Price, Jr. was born in St Louis, Missouri, to Marguerite Cobb (Wilcox) and Vincent Leonard Price, Sr., president of the National Candy Company. He traveled through Europe, studied at Yale and became an actor.
Mayra Rosales (born 1980) is one of the world's heaviest people, currently weighing an estimated 343 kg (756 lb; 54 st). At her heaviest, she weighed 470 kg (1,000 lb; 74 st). She came to prominence in March 2008, when she was accused of the murder of her two year old nephew.