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If you have celiac disease, eating gluten causes inflammation in your intestines. As a result, you may not absorb nutrients properly and may develop nutritional deficiencies. These can progress to problems such as iron-deficiency anemia, osteoporosis and infertility issues.
The exact cause of celiac disease is unknown. The lining of the intestines have small areas called villi which project outward into the opening of the intestine. These structures help absorb nutrients. When people with celiac disease eat foods with gluten, their immune system reacts by damaging the villi.