GFR is related inversely and nonlinearly to serum creatinine. Age, gender, and race all affect muscle mass and, in turn, serum creatinine. Both the MDRD Study and CKD-EPI equations include variables to account for serum creatinine variation with age, gender, and race.
When a nerve is stimulated, its cell membrane is depolarised so that the inside of the cell becomes less negative. The potential is conducted along the axon to the axon termin â¦ al.At the dendrite it stimulates the release of a chemical transmitter, which diffuses across a synapse.The transmitter binds to receptor sites on the postsynaptic cell membrane to stimulate the generation of another impulse.+ 4 others found this useful.t the dendrite it stimulates the release of a chemical transmitter, which diffuses across a synapse. The transmitter binds to receptor sites on the postsynaptic cell membrane to stimulate the generation of another impulse. + 4 others found this useful.
5.2.1 Structure and Function of the Synapse. 1  An action pulse reaches the terminal endings of the presynaptic cell. 2  A neurotransmitter is released, which diffuses across the synaptic gap to bind to receptors in specialized membranes of the postsynaptic cell. Development of a receptor voltage, which is the graded response of the receptor to the stimulus. 2  It is the initial electric event in the receptor. 3  Subsequent buildup of a generator voltage, which is the electric phenomenon that triggers impulse propagation in the axon.