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A Sharecare Ad Target User , Administration, answered. An outbreak of oral herpes, or cold sores, should go away on its own in about one or two weeks. Antiviral medications can help them heal faster if taken early. Talk to your doctor if your cold sores do not go away after two weeks. Helpful? 1 person found this helpful.
There is no cure for herpes, so the goals of treatment are to reduce the number of outbreaks and to lessen symptoms when you do have an outbreak. Cold sores usually go away by themselves within 2 to 3 weeks, however, they can last for us to 6 weeks. Using medications may shorten the outbreak and decrease discomfort.here is no cure for herpes, so the goals of treatment are to reduce the number of outbreaks and to lessen symptoms when you do have an outbreak. Cold sores usually go away by themselves within 2 to 3 weeks, however, they can last for us to 6 weeks. Using medications may shorten the outbreak and decrease discomfort.