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The hypothalamus is a brain structure made up of distinct nuclei as well as less anatomically distinct areas. It is found in all vertebrate nervous systems. In mammals, magnocellular neurosecretory cells in the paraventricular nucleus and the supraoptic nucleus of the hypothalamus produce neurohypophysial hormones, oxytocin and vasopressin. These hormones are released into the blood in the posterior pituitary.
1 It is composed largely of the axons of hypothalamic neurons which extend downward as a large bundle behind the anterior pituitary. 2  It also forms the so-called pituitary stalk, which appears to suspend the anterior gland from the hypothalamus.