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Schwann cells are the supporting cells of the PNS. Like oligodendrocytes schwann cells wrap themselves around nerve axons, but the difference is that a single schwann cell makes up a single segment of an axon's myelin sheath.
Depending on the location, different glial cell types make myelin in a different manner. Schwann cells make myelin in the peripheral nervous system (PNS: nerves) and oligodendrocytes in the central nervous system (CNS: brain and spinal cord). In the PNS, one Schwann cell forms a single myelin sheath (Figure 1A).he ratio between axon diameter and that of the total nerve fiber (axon and myelin) is 0.6â0.7, a ratio that is well maintained regardless of the axon caliber. The length of the myelin sheath along the axon is approximately 1 mm in the PNS.