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Low or normal TSH, low free T3 or T4 Low or normal TSHand low free T3 or T4 test resultsrepresent a typical pattern in unwell patients with non-thyroidal illness, the most common combination of resultsbeing a low free T3 with a TSH in the normal range(panel 4).ge of onset varies from the neonatalperiod to adulthood, and a smooth or multinodular goitrecan develop. 20,21 Closely similar somatic mutations areresponsible for 80% of toxic nodules. Low TSH, normal free T3 or T4 Low TSH and normal free T3 and T4 test results areusually seen with thyroxine ingestion (panel 3).
If the T4 is in the low (but still ânormalâ) range and the T3 is to the right of it in the low but normal range, it means that the T4 is converting to T3 at a high rate (more T3, less RT3). This is typically found when the thyroid gland is unable to keep up T4 production to meet the bodyâs needs.n the cases of Free T4 (FT4) and Free T3 (FT3), the optimal zone is roughly half way between the usual lab normal Low-High values. Note that the normal range for these hormones may change a bit from lab to lab. In the case of TSH, the optimal zone is skewed far toward the low end of the standard lab Low-High range.