Scleritis (inflammation of sclera) is a strong indication of the underlying medical problem. It can be due to fungal, viral or parasitic infection, trauma, exposure to chemicals, poisonous gases or due to post-surgical complications.
Mast cells are granulated cells typically found in connective tissue. These cells mediate immune responses to foreign particles. In particular, they release large amounts of histamine and enzymes in response to antigen recognition.
When you catch cold, secretion of Histamine increases in your body. This Histamine then stimulates mast cells to release other inflammatory mediators such as TNF-alpha, IL-6 & IL-b. These inflammatory mediators increase the permeability of blood vessels.