For example, your standard fixed overhead cost is $3 per unit. If your actual fixed overhead cost is $4 per unit, you have an unfavorable variance of $1. You spent $1 more per unit than you had originally budgeted.
In biology, histones are highly alkaline proteins found in eukaryotic cell nuclei that package and order the DNA into structural units called nucleosomes. They are the chief protein components of chromatin, acting as spools around which DNA winds, and playing a role in gene regulation. Without histones, the unwound DNA in chromosomes would be very long (a length to width ratio of more than 10 million to 1 in human DNA).
There are four types of histones found in chromatin: H2A, H2B, H3, and H4. Two of each histone comprise a protein core, a nucleosome, which DNA wraps around twice.What results is a bead on a string model in which the nucleosomes are the beads and the linker DNA binds them together.Another characteristic of histones are the protein tails that extend outward from the bead..The tails and the degree of their acetylation is an important factor in gene expression.hat results is a bead on a string model in which the nucleosomes are the beads and the linker DNA binds them together. Another characteristic of histones are the protein tails that extend outward from the bead.. The tails and the degree of their acetylation is an important factor in gene expression.