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Facial pain can be caused by anything from an infection to nerve damage in the face. Common causes for facial pain include: 1  oral infections. 2  ulcers (open sores). 3  abscess (collection of pus under the surface tissue in the mouth, for example). 4  skin abscess (collection of pus under the skin).5  headache.6  facial injury.7  toothache.ommon causes for facial pain include: 1  oral infections. 2  ulcers (open sores). 3  abscess (collection of pus under the surface tissue in the mouth, for example). 4  skin abscess (collection of pus under the skin). 5  headache. 6  facial injury. 7  toothache.
Most of the other causes a systemic, meaning that it affects the entire body or several systems of the body simultaneously. It is unlikely to cause one sided facial swelling but instead swelling of the entire face. Nevertheless it is worth considering these conditions as a possible cause of one sided facial swelling. 1  Cushingâs disease. 2  Kidney failure. 3  Heart failure.  Liver 1  failure. Serum sickness. 2  Malnutrition. Obesity.