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The organ system in which the blood is pumped through the heart and circulates throughout the body through the blood vessels. Supplement. The cardiovascular system is a closed circulatory system seen in humans and other vertebrates. Its components include the heart, blood vessels, and blood.
The heart is the core of the cardiovascular system. Your cardiovascular system consists of your heart and the blood vessels that carry blood throughout your body. Your heart is located to the left of the middle of your chest. It is a large muscle about the size of your fist. It works as a pump.