1 Coadministration with moderate CYP3A4 and/or PgP inhibitors: Reduce dose by 50%; administer every other day if dose reduction is required for patients receiving the lowest available strength and maintain trough concentrations of 5 to 15 ng/mL.
A pregnant mouse can give birth to six to 12 babies in one litter. A female mouse can become pregnant several times a year. One mouse couple can produce 40 or more babies in one year.
1 Rats are pregnant for 21 to 25 days, they can have them as early as 21 days on occasion they may go as long as 28 days.  Some people swear they have babies every 21 days, mine typically have them at 25 days.