GeneCards Summary for CHAT Gene. CHAT (Choline O-Acetyltransferase) is a Protein Coding gene. Diseases associated with CHAT include Myasthenic Syndrome, Congenital, 6, Presynaptic and Congenital Myasthenic Syndrome With Episodic Apnea. Among its related pathways are Metabolism and Transmission across Chemical Synapses.
FREE subscriptions for doctors and students... click hereYou have 3 open access pages. Ludwig's angina is an acute cellulitis in the region of the submandibular gland. It is most commonly due to sepsis in the throat or mouth which migrates to the submandibular space.Occasionally, it may be the result of suppuration in the submandibular gland itself.1  it is necessary to consider the anatomy of the submandibular space in order to understand the pathophysiology of Ludwig's angina.t is most commonly due to sepsis in the throat or mouth which migrates to the submandibular space. Occasionally, it may be the result of suppuration in the submandibular gland itself. 1  it is necessary to consider the anatomy of the submandibular space in order to understand the pathophysiology of Ludwig's angina.
The following can cause excessive production of cortisol or ACTH, leading to Cushing's syndrome. 1  Pituitary gland tumors: A benign (non-cancerous) tumor of the pituitary gland can secrete an excess amount of ACTH, which can cause Cushing's syndrome.he cause of Cushing's syndrome boils down to: Your body is exposed to too much cortisol. There are a few ways that this over-exposure can happen, including taking certain medications and having a tumor on your pituitary gland or adrenal gland.