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A Sharecare Ad Target User , Administration, answered. An outbreak of oral herpes, or cold sores, should go away on its own in about one or two weeks. Antiviral medications can help them heal faster if taken early. Talk to your doctor if your cold sores do not go away after two weeks. Helpful? 1 person found this helpful.
Topics covered: how long cold sores last, how to get rid of cold sores in one day, and how to get rid of a cold sore fast overnight. Cold sores, also known as fever blisters, are viral infections caused by the virus herpes simplex virus-1.