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Who discovered the disease malaria? Who discovered the malaria disease and when? Malaria has been known for thousands of years; there are written accounts of the disease, including a description of its symptoms, in ancient Chinese medical texts from 2700 BCE. The ancient Romans and Greeks also knew about malaria. However, the causes of the disease were only discovered in the 19th century. In 1880, a French surgeon called Charles Louis Alphonse Laveran stationed in Algeria was the first person to see the parasites that cause malaria in the blood of an infected person.
Malaria is a major world health problem. It results from infection of parasites belonging to the genus Plasmodium. Plasmodium falciparum and Plasmodium vivax cause the major human malarias, with P falciparum being the more virulent. During their blood stages of infection, both P falciparum and P vivax induce anemia.Severe malarial anemia caused by P falciparum is responsible for approximately a third of the deaths associated with disease. strength of the model is that it mimics human malaria anemia where low parasitemias are seen concomitant with severe anemia through the duration of infection. The disadvantage is that the time needed to generate semi-immune mice requires 5 or more months with constant injections of parasites and drug combinations.