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Pulmonary edema facts. 1  Pulmonary edema is typically caused by filling of alveoli in the lungs by fluid leaking out of the blood. 2  Pulmonary edema may be caused by a number of cardiac or non-cardiac conditions.  Breathing difficulty is the main manifestation of pulmonary edema.
When fluid accumulates in the lungs because of high blood pressure, you have a condition called pulmonary edema. It occurs when long-term hypertension weakens your heartâs left ventricle (normally the strongest part of your heart muscle). Fluids then back up in the lungs, making it difficult to breathe.