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Skin lesions have a wide variety of causes. The most common causes of skin lesions are injury, aging, infectious diseases, allergies, and small infections of the skin or hair follicles.Chronic diseases such as diabetes or autoimmune disorders can cause skin lesions.Skin cancer or precancerous changes also appear as skin lesions.ommon causes of skin lesions. Changes in the appearance of the skin can result from common conditions such as: 1  Acne. 2  Boils and carbuncles. 3  Folliculitis. 4  Freckles. 5  Nevi (moles) and other benign skin growths.
Peeling of skin, scientifically known as desquamation, is the loss of the outer layer of your skin. Skin peeling may be caused due to direct damage to the skin or due to different types of serious diseases, disorders and conditions. Skin peeling may occur on small area or the entire body to different age groups.ue to the range of the causes of skin peeling, treatment should be given depending on the condition. It may cause blisters or sores, fever, diarrhea, pain, vomiting, swelling etc. Life threatening causes include toxic shock syndrome.