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Some medications may cause bloating and weight gain because they encourage your body to retain fluid. The extra weight is often due to swelling, or edema, from this excess fluid. Some medications known to cause weight gain include steroids, tranquilizers, some antidepressants and lithium.
Timing exchanges (generally after meals) helps relieve some of the discomfort. 3. Bloating and weight gain. Bloating and weight gain are common complaints while on PD. Some of the weight gain is fluid bloat from the dialysis solution sitting in the peritoneum. Weight gain can also come from the sugar in the dialysis solution being absorbed by the body and lead to extra pounds.