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In addition, Lamictal is commonly prescribed to adults with bipolar disorder (manic depression) to delay episodes of depression and mania. (Mania is defined as frenzied or abnormally excited moods). Lamictal is also prescribed off-label to treat clinical depression and migraine headaches. The FDA first approved Lamictal in 1994 as an anti-seizure medication. Approval to use the drug in the treatment of bipolar disorder was given in 2003.
The immediate-release form of lamotrigine (Lamictal, Lamictal ODT) can be used in children as young as 2 years old when it is given as part of a combination of seizure medications. However, this form should not be used as a single medication in a child or teenager who is younger than 16 years old. The extended-release form of lamotrigine (Lamictal XR) is for use only in adults and children who are at least 13 years old.