GFR is related inversely and nonlinearly to serum creatinine. Age, gender, and race all affect muscle mass and, in turn, serum creatinine. Both the MDRD Study and CKD-EPI equations include variables to account for serum creatinine variation with age, gender, and race.
When a nerve is stimulated, its cell membrane is depolarised so that the inside of the cell becomes less negative. The potential is conducted along the axon to the axon termin â¦ al.At the dendrite it stimulates the release of a chemical transmitter, which diffuses across a synapse.The transmitter binds to receptor sites on the postsynaptic cell membrane to stimulate the generation of another impulse.+ 4 others found this useful.t the dendrite it stimulates the release of a chemical transmitter, which diffuses across a synapse. The transmitter binds to receptor sites on the postsynaptic cell membrane to stimulate the generation of another impulse. + 4 others found this useful.
Let's take a look at what occurs within a skeletal muscle, from excitation to contraction to relaxation 1  : An electrical signal (action potential) travels down a nerve cell, causing it to release a chemical message (neurotransmitter) into a small gap between the nerve cell and muscle cell. 2  This gap is called the synapse.he trigger for a muscle contraction is an electrical impulse. The electrical signal sets off a series of events that lead to crossbridge cycling between myosin and actin, which generates force.