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The organ system in which the blood is pumped through the heart and circulates throughout the body through the blood vessels. Supplement. The cardiovascular system is a closed circulatory system seen in humans and other vertebrates. Its components include the heart, blood vessels, and blood.
Also known as: CVD. Cardiovascular disease (CVD) is a general term used to describe disorders that can affect the heart (cardio) and/or the body's system of blood vessels (vascular).Most cardiovascular diseases reflect chronic conditions â conditions that develop or persist over a long period of time.n addition, there are some risk factors that cannot be controlled, including age, gender, and family history: 1  CVD risk increases with age. 2  Men are generally at higher risk of heart disease; however, women's risk increases to that of men's after menopause.