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Skin lesions have a wide variety of causes. The most common causes of skin lesions are injury, aging, infectious diseases, allergies, and small infections of the skin or hair follicles.Chronic diseases such as diabetes or autoimmune disorders can cause skin lesions.Skin cancer or precancerous changes also appear as skin lesions.ommon causes of skin lesions. Changes in the appearance of the skin can result from common conditions such as: 1  Acne. 2  Boils and carbuncles. 3  Folliculitis. 4  Freckles. 5  Nevi (moles) and other benign skin growths.
Styes are usually caused by a combination of a clogged oil gland and staphylococcal bacteria, which often live right on the skin surface. Our bodies are coated with billions of friendly bacteria that coexist with us. When the conditions are right, the bacteria become overabundant, resulting in the tender pimple. stye is a pimple or abscess that forms in either the upper or lower eyelid. It is an inflammation caused by blockage of an oil duct and bacteria that normally live on the surface of the eyelid without any problems. Some germs can get trapped along with dead skin cells along the edge of the eyelid.