GeneCards Summary for CHAT Gene. CHAT (Choline O-Acetyltransferase) is a Protein Coding gene. Diseases associated with CHAT include Myasthenic Syndrome, Congenital, 6, Presynaptic and Congenital Myasthenic Syndrome With Episodic Apnea. Among its related pathways are Metabolism and Transmission across Chemical Synapses.
FREE subscriptions for doctors and students... click hereYou have 3 open access pages. Ludwig's angina is an acute cellulitis in the region of the submandibular gland. It is most commonly due to sepsis in the throat or mouth which migrates to the submandibular space.Occasionally, it may be the result of suppuration in the submandibular gland itself.1  it is necessary to consider the anatomy of the submandibular space in order to understand the pathophysiology of Ludwig's angina.t is most commonly due to sepsis in the throat or mouth which migrates to the submandibular space. Occasionally, it may be the result of suppuration in the submandibular gland itself. 1  it is necessary to consider the anatomy of the submandibular space in order to understand the pathophysiology of Ludwig's angina.
Ludwigâs angina is a life-threatening infection of the connective tissue of the submandibular or sublingual area (located on the floor of the mouth).It was named after Wilhelm Friedrich von Ludwig, a German physician who first knew about the disease in 1836.ymptoms of Ludwigâs angina include: 1  Swelling of the submandibular and sublingual areas. 2  Pain on the tongue and neck. 3  Redness and swelling of the neck. 4  Fever. 5  Malaise, weakness and fatigue. 6  Dysphagia or difficulty in swallowing. 7  Drooling. 8  Difficulty breathing.