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The symptoms of schizoaffective disorder can include: 1  Changes in appetite and energy. 2  Disorganized speech that is not logical.  False beliefs (delusions), such as thinking someone is trying to harm you (paranoia) or thinking that special messages are hidden in common places (delusions of reference)
1 Schizophrenia. 2  Depressed mood, mania, or other symptoms may be present in patients with schizophrenia, but patients with schizoaffective disorder will meet all the criteria set out for a full-blown mood disorder. 3  Medical and neurological disorders that mimic psychotic/affective disorders.ntipsychotic medications used to treat schizophrenia and the antidepressant drugs and mood stabilizers used in depression and bipolar disorder are the primary treatments for schizoaffective disorder.