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A nucleated red blood cell, or NRBC, is a red blood cell (RBC) that retains nucleus. Normally, NRBCs are only found in the circulation of fetuses and newborn infants. nucleated red blood cell, or NRBC, is a red blood cell (RBC) that retains nucleus. Normally, NRBCs are only found in the circulation of fetuses and newborn infants.
In contrast, a nucleated red blood cell (NRBC), also known by several other names, is a mammalian RBC that contains a cell nucleus. NRBCs occur in normal development as progenitor cells in the erythropoietic lineage and in pathological states.