Gastrointestinal: Adjective referring collectively to the stomach and small and large intestines. The commonly used abbreviation for gastrointestinal is GI. (Outside of medicine, GI can also stand for galvanized iron, general issue or government issue-as in GI Joe).
Before the extracellular matrix is calcified, the tissue is called osteoid (bone-like) tissue. When the concentrations of calcium and phosphate ions rise high enough, they are deposited into the extracellular matrix, and the bone calcifies.
Sesamoid bones are small more or less rounded masses embedded in certain tendons and usually related to joint surfaces. Their functions probably are to modify pressure, to diminish friction, and occasionally to alter the direction of a muscle pull.