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Symptoms of Schizoaffective Disorder. The symptoms of a schizoaffective disorder vary tremendously from person to person. A person with schizoaffective disorder usually has severe changes in mood and some of the psychotic symptoms of schizophrenia, such as hallucinations, delusions and disorganized thinking. Both men and women with the disorder are also known to shy away or even completely avoid most social situations.
1 Schizophrenia. 2  Depressed mood, mania, or other symptoms may be present in patients with schizophrenia, but patients with schizoaffective disorder will meet all the criteria set out for a full-blown mood disorder. 3  Medical and neurological disorders that mimic psychotic/affective disorders.ntipsychotic medications used to treat schizophrenia and the antidepressant drugs and mood stabilizers used in depression and bipolar disorder are the primary treatments for schizoaffective disorder.