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Compared to other drugs in its class, fluoxetine generally causes less severe withdrawal symptoms due to its long half-life. Here are some things that might happen if you quit taking it cold turkey: Neurological: The emotional and mental effects of fluoxetine withdrawal are often among the most troubling.ere are some things that might happen if you quit taking it cold turkey: Neurological: The emotional and mental effects of fluoxetine withdrawal are often among the most troubling.
Assuming you fully quit taking the drug, you may start to notice Prozac withdrawal symptoms slowly emerge within 2 to 4 weeks after discontinuation. Though Prozac is considered among the easiest antidepressants to discontinue due to its long half-life, it also stays in your system for a long time after stopping.