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Some medications may cause bloating and weight gain because they encourage your body to retain fluid. The extra weight is often due to swelling, or edema, from this excess fluid. Some medications known to cause weight gain include steroids, tranquilizers, some antidepressants and lithium.
The inflammation linked to Crohnâs can give you nausea and diarrhea, as well as curb your appetite. As a result, you may eat less, making it harder to keep weight on. Some Crohn's medicines may also affect your weight. Corticosteroids such as prednisone can cause temporary weight gain.