1 Coadministration with moderate CYP3A4 and/or PgP inhibitors: Reduce dose by 50%; administer every other day if dose reduction is required for patients receiving the lowest available strength and maintain trough concentrations of 5 to 15 ng/mL.
A pregnant mouse can give birth to six to 12 babies in one litter. A female mouse can become pregnant several times a year. One mouse couple can produce 40 or more babies in one year.
Litter Size. Just as in their human counterparts, big litters are harder on the femaleâs body than single births. First-time queens normally have a maximum of three or four kittens, but experienced mothers may have as many as 10 or 12 in a single litter. As a general rule, the number of kittens in a litter determines how quickly they can leave the nest: the bigger the family, the sooner they learn how to be cats.