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If you have celiac disease, eating gluten causes inflammation in your intestines. As a result, you may not absorb nutrients properly and may develop nutritional deficiencies. These can progress to problems such as iron-deficiency anemia, osteoporosis and infertility issues.
Celiac patients who go gluten-free may find that they gain weight, says Crowe. While eating gluten, malabsorption of nutrients could allow someone to eat 3,000 calories a day without noticing. Once off gluten, as the small intestine heals, the 3,000 calories a day start to catch up with him, she says.