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Denis transfused the blood from a sheep to a 15-year old boy and later to a labourer, both of whom survived the transfusions. In 1818, British obstetrician James Blundell successfully transfused human blood to a patient who had hemorrhaged during childbirth. In 1901, Karl Landsteiner, an Austrian physician discovered the first human blood groups, which helped transfusion to become a safer practice.
See Bombay O blood group (hh blood group) first discovered in Bombay, India in 1952 as an example of a group of people with O blood type that can only receive the same blood group and any other bloods (O, A, B, AB, Rh+ or Rh-) will lead them to acute hemolytic transfusion reaction.