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Depression and anxiety may also cause you to eat more and exercise less than normal. Metabolic or hormonal disruptions, such as hypothyroidism or polycystic ovary syndrome, can cause sudden weight gain and bloating. Cushing's disease can also cause rapid weight gain, especially in the upper body.
Timing exchanges (generally after meals) helps relieve some of the discomfort. 3. Bloating and weight gain. Bloating and weight gain are common complaints while on PD. Some of the weight gain is fluid bloat from the dialysis solution sitting in the peritoneum. Weight gain can also come from the sugar in the dialysis solution being absorbed by the body and lead to extra pounds.