1 The processing time does not apply to services where prior approval has to be obtained from authorities in India or elsewhere. For such cases, the processing time is a minimum of thirty (30) business days.  The Consular Officer can at any time call an applicant for a personal interview.
Causes of Simian crease that are rare The offical US government definition of a rare disease is one that affects 200,000 people or less. The following causes of Simian crease appear in the population at a rate of less than 200,000 people per year in the USA: Coffin-Lowry syndrome - simian crease.
What are the Causes of Coffin-Lowry Syndrome? Coffin-Lowry syndrome is caused by a mutation in the RPS6KA3 gene found on the X chromosome. The defective gene results in the defect in a protein, which is involved in several important functions of the body including in the brain.