For example, your standard fixed overhead cost is $3 per unit. If your actual fixed overhead cost is $4 per unit, you have an unfavorable variance of $1. You spent $1 more per unit than you had originally budgeted.
In biology, histones are highly alkaline proteins found in eukaryotic cell nuclei that package and order the DNA into structural units called nucleosomes. They are the chief protein components of chromatin, acting as spools around which DNA winds, and playing a role in gene regulation. Without histones, the unwound DNA in chromosomes would be very long (a length to width ratio of more than 10 million to 1 in human DNA).
Best Answer: Histones are the proteins closely associated with DNA molecules. They are responsible for the structure of chromatin and play important roles in the regulation of gene expression. Five types of histones have been identified: H1 (or H5), H2A, H2B, H3 and H4.H1 and its homologous protein H5 are involved in higher-order structures of chromatin. The other four types of histones associate with DNA to form nucleosomes. H1 (or H5) has about 220 residues.Other types of histones are smaller, each consisting of 100-150 residues. Each nucleosome consists of 146 bp DNA and 8 histones: two copies for each of H2A, H2B, H3 and H4.ive types of histones have been identified: H1 (or H5), H2A, H2B, H3 and H4. H1 and its homologous protein H5 are involved in higher-order structures of chromatin. The other four types of histones associate with DNA to form nucleosomes.