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The organ system in which the blood is pumped through the heart and circulates throughout the body through the blood vessels. Supplement. The cardiovascular system is a closed circulatory system seen in humans and other vertebrates. Its components include the heart, blood vessels, and blood.
Cardiovascular disease is a term that refers to more than one disease of the circulatory system including the heart and blood vessels, whether the blood vessels are affecting the lungs, the brain, kidneys or other parts of the body. Cardiovascular diseases are the leading cause of death in adult Canadian men and women.