A written agreement which explicitly states a fixed duration that the contract will be in effect. The signing parties are obligated to adhere to the terms and conditions within the contract until the expiration, or end date, of the contract. http://www.businessdictionary.com/definition/term-contract.html.
The most common symptoms of Lou Gehrig's Disease are: 1  twitching. 2  cramping, or stiffness of muscles. 3  muscle weakness affecting an arm or a leg.  slurred and nasal 1  speech. or difficulty chewing or swallowing.
Quick Answer. Early symptoms of Lou Gehrig's disease, also known as ALS, include muscle weakness in the hands, arms or legs, twitching of the muscles and difficulty projecting the voice, describes the ALS Association. In more advanced stages, patients have trouble swallowing and breathing, and often feel short of breath.