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A Sharecare Ad Target User , Administration, answered. An outbreak of oral herpes, or cold sores, should go away on its own in about one or two weeks. Antiviral medications can help them heal faster if taken early. Talk to your doctor if your cold sores do not go away after two weeks. Helpful? 1 person found this helpful.
Rubbing Alcohol. Rubbing alcohol works to dry the cold sore so that it heals. It also helps to reduce the duration by decreasing the risk of bacterial contamination. To use rubbing alcohol, make sure you get a 70 percent solution which is available at drug stores.