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A Sharecare Ad Target User , Administration, answered. An outbreak of oral herpes, or cold sores, should go away on its own in about one or two weeks. Antiviral medications can help them heal faster if taken early. Talk to your doctor if your cold sores do not go away after two weeks. Helpful? 1 person found this helpful.
Quick Answer. Cold sores usually go way within 2 weeks, although they can go away in just 2 to 3 days. Cold sores are also known as fever blisters. They are small blisters that generally cluster around the mouth.