1 Coadministration with moderate CYP3A4 and/or PgP inhibitors: Reduce dose by 50%; administer every other day if dose reduction is required for patients receiving the lowest available strength and maintain trough concentrations of 5 to 15 ng/mL.
A pregnant mouse can give birth to six to 12 babies in one litter. A female mouse can become pregnant several times a year. One mouse couple can produce 40 or more babies in one year.
With an average lifespan of 18 months, and an average of 10 babies per litter, a single female mouse can produce more than 300 offspring in her lifetime, making careful sexing a necessity unless you wish to become a mouse breeder.