Pain in the ankle can result from inflammation or injury to any of the structures in this region, including the bones, joint space, cartilage, ligaments, tendons, or muscles. Ankle pain can be associated with other symptoms including.
People with Down syndrome may have some or all of these physical characteristics: a small chin, slanted eyes, poor muscle tone, a flat nasal bridge, a single crease of the palm, and a protruding tongue due to a small mouth and relatively large tongue.
Most children with Down syndrome have: 1  Distinctive facial features, such as a flat face, small ears, slanting eyes, and a small mouth. 2  A short neck and short arms and legs. 3  Low muscle tone and loose joints. Muscle tone usually improves by late childhood.  Below-average intelligence.