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Quinine is only approved for the treatment of malaria. Tonic water contains quinine but it does not have enough quinine to help with leg cramps. Common side effects associated with quinine can include headache, nausea, diarrhea, vomiting, hives, fever, ringing in the ears, vision problems, and bleeding problems.
Report Abuse. Tonic water originally contained only carbonated water and a large amount of quinine. However, most tonic water today contains a medically insignificant amount of quinine, and is thus used for its flavor only. It is consequently less bitter, and is also usually sweetened.Quinine derives from the bark of the Cinchona, a tree grown in the Andes.onic water, however, contains too little quinine to actually prevent malaria. Actually, chemically produced quinine in much larger doses is now preferred. Quinine therapy does not exactly kill malaria either, but tends to reduce fever and malarial symptoms.