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Carbon dioxide is released during two phases of cellular respiration. The first phase that carbon dioxide leaves is during pyruvate decarboxylation. The second time CO2 is released is during the Kreb's cycle.
One way to view cellular respiration is to relate it to breathing. Both breathing and cellular respiration take in oxygen and release carbon dioxide. As you will see in this chapter, the oxygen made available to the cells of the body via breathing makes the aerobic portion of cellular respiration possible.