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In the cell membrane, hydrophilic heads orient to the inside and outside of the membrane, with the hydrophobic molecules inside. This gives the membrane its semi permeable fluid nature.he hydrophilic region in the cell is water-loving and it  attracts the water molecules. It is basically composed of polar  groups which readily dissolve and absorb water.
b. If phospholipid molecules are surrounded by water, their hydrophobic fatty acid tails cluster and a bilayer results; hydrophilic heads are at the outer faces of a two-layer sheet. c. Bilayers of phospholipids are the structural foundation for all cell membranes.2.. If phospholipid molecules are surrounded by water, their hydrophobic fatty acid tails cluster and a bilayer results; hydrophilic heads are at the outer faces of a two-layer sheet. c. Bilayers of phospholipids are the structural foundation for all cell membranes.