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Cephalexin is prescribed to treat respiratory tract, middle ear, skin, bone, and urinary tract infections (UTI). It's also used to prevent infections caused by streptococcal bacteria, including prevention of rheumatic fever.Cephalexin isn't recommended for sinus infections.Cephalexin is sometimes called a first-generation cephalosporin because it was one of the first cephalosporins developed and marketed.ere are general guidelines for cephalexin dosage: 1  The usual adult dose ranges from 1 to 4 grams a day, given in divided doses. 2  Typical adult doses of cephalexin are 250 mg every 6 hours, or 500 mg every 12 hours. 3  The usual dose for a child is 25 to 50 milligrams (mg) per kilogram of weight, given in divided doses.
Keflex (cephalexin) is administered orally. Adults â The adult dosage ranges from 1 to 4 g daily in divided doses. The 333 mg and 750 mg strengths should be administered such that the daily dose is within 1 to 4 grams per day. The usual adult dose is 250 mg every 6 hours.For the following infections, a dosage of 500 mg may be administered every 12 hours: streptococcal pharyngitis, skin and skin structure infections, and uncomplicated cystitis in patients over 15 years of age. Cystitis therapy should be continued for 7 to 14 days.f daily doses of Keflex (cephalexin) greater than 4 g are required, parenteral cephalosporins, in appropriate doses, should be considered. Pediatric Patients â The usual recommended daily dosage for pediatric patients is 25 to 50 mg/kg in divided doses.