As a research vessel HMS Beagle may not have had the internet, but she did have an impressive state-of-the-art library of about 400 volumes. The library was housed in book cases in the poop cabin at the stern of the ship, which was also Darwin's cabin. Thus, Darwin lived and worked in the Beagle library for five years.
Nexium should only be taken as often as recommended. When used to heal erosive esophagitis, 20 mg or 40 mg should be taken daily for four to eight weeks. When used for the maintenance of erosive esophagitis healing, 20 mg of Nexium should be taken daily for as long as recommended. This medication should always be taken one hour before a meal with a full glass of water.
My gastro-enterologist explained to me that Nexium actually needs food to work properly. Apparently the requirement that you need to take it for 1 hour before a meal is because of this: The Nexium first needs to prepare certain conditions in your stomach, which it takes a little while to do. It then reacts to the food that you eat later and starts working.