Pain in the ankle can result from inflammation or injury to any of the structures in this region, including the bones, joint space, cartilage, ligaments, tendons, or muscles. Ankle pain can be associated with other symptoms including.
People with Down syndrome may have some or all of these physical characteristics: a small chin, slanted eyes, poor muscle tone, a flat nasal bridge, a single crease of the palm, and a protruding tongue due to a small mouth and relatively large tongue.
Symptoms. Each person with Down syndrome is an individual â intellectual and developmental problems range from mild to moderate, and some people are healthy while others have severe health problems such as serious heart defects. Children with Down syndrome have a distinct facial appearance. Though not all children with Down syndrome have the same features, some of the more common features are: 1  Flattened facial features. 2  Small head. 3  Short neck. 4  Protruding tongue. 5  Upward slanting eyes, unusual for the child's ethnic group. 6  Unusually shaped or small ears.