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Low levels of high-density lipoprotein cholesterol (HDL), or hypoalphalipoproteinemia (HA), includes a variety of conditions, ranging from mild to severe, in which concentrations of alpha lipoproteins or high-density lipoprotein (HDL) are reduced.
HDL travels throughout the bloodstream, collecting cholesterol and carrying it back to the liver for breakdown and disposal. Causes of low levels of HDL cholesterol include genetics, a lack of exercise and dietary factors.