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In the cell membrane, hydrophilic heads orient to the inside and outside of the membrane, with the hydrophobic molecules inside. This gives the membrane its semi permeable fluid nature.he hydrophilic region in the cell is water-loving and it  attracts the water molecules. It is basically composed of polar  groups which readily dissolve and absorb water.
1 Draw the structure of a phospholipid and membrane bilayer and label the hydrophilic and hydrophobic regions. 2  Describe the consequence of damage to the cell membrane on the viability of cells.  Compare the structure of proteins that function as channels to proteins that function as receptors.