Pain in the ankle can result from inflammation or injury to any of the structures in this region, including the bones, joint space, cartilage, ligaments, tendons, or muscles. Ankle pain can be associated with other symptoms including.
People with Down syndrome may have some or all of these physical characteristics: a small chin, slanted eyes, poor muscle tone, a flat nasal bridge, a single crease of the palm, and a protruding tongue due to a small mouth and relatively large tongue.
A patient with trisomy 21 has three copies of chromosome 21. Down syndrome is classified as a genetic â¦ disorder and it includes a combination of characteristic facial features, often some degree of mental retardation, and sometimes heart defects. Many people with Down syndrome also have hearing and vision problems.