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In many cases the knot in the muscle is caused by an abnormal nerve message being sent to the muscle. The abnormal nerve message is, in turn, caused by a misaligned bone in the spine that irritates the nerve. To keep it simple.
Muscle knots, also referred to as myofascial trigger points, are described as abnormal areas in the muscle, according to Seth Rosenbaum, M.D. Muscle knots often form when the muscle is experiencing a spasm. A muscle spasm occurs when a muscle is in a continuous contraction and typically follows an injury.t is characterized by having ongoing painful trigger points, or muscle knots, according to the MayoClinic.com. This pain tends to worsen or persist. Trigger point injections, physical therapy and medications can help to alleviate the pain and muscle knots.