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Runners and other athletes are also prone to calf tightness, as the calf muscles are constantly firing to stabilize the ankle and both absorb each landing and push the heel back off the ground. Interestingly, calf tightness can also be symptomatic of weakness elsewhere in the leg. If your glutes and/or hamstrings are weak, your calves will often try to make up for that weakness, which means the muscle gets overused, which in turn exacerbates calf tightness.
Some of the more common causes of calf pain include: 1  Calf Muscle Strain. A calf muscle strain is the most common cause of acute onset calf pain. 2  Medial Gastrocnemius Strain. The medial gastrocnemius is the part of the calf muscle most commonly injured. 3  Plantaris Muscle Rupture.