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Overuse and inappropriate prescribing of antibiotics worldwide is leading to the global healthcare issue of antibiotic resistance. However, the issue of antibiotic resistance can be confusing for many patients. You may be told you cannot use an antibiotic for a viral infection because they are ineffective and may lead to âantibiotic resistanceâ.
Several classes of antibiotics are effective against atypical pathogens. However, because C. pneumoniae and Legionella species are intracellular organisms and M. pneumoniae lacks a cell wall, beta-lactams are not effective. Erythromycin and, in some cases, tetracycline have been traditional choices for the treatment of pneumonia caused by atypical pathogens. There are few (if any) clinical trials demonstrating the efficacy of erythromycin for Legionella infection.