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Heroin can be used in a variety of ways, depending on user preference and the purity of the drug. Heroin can be injected into a vein (âmainliningâ), injected into a muscle, placed on tinfoil and inhaled as smoke through a straw or snorted as powder via the nose.eroin can be used in a variety of ways, depending on user preference and the purity of the drug. Heroin can be injected into a vein (âmainliningâ), injected into a muscle, placed on tinfoil and inhaled as smoke through a straw or snorted as powder via the nose.
People who use heroin report feeling a rush (euphoria) accompanied by effects that include: 1  dry mouth. 2  flushing of the skin. 3  heavy feelings in the hands and feet.  clouded mental 1  functioning. going on the nod, a back-and-forth state of being conscious and semi-conscious.