Pretest-posttest designs grew from the simpler posttest only designs, and address some of the issues arising with assignment bias and the allocation of participants to groups. One example is education, where researchers want to monitor the effect of a new teaching method upon groups of children.
A neuromuscular junction (sometimes called a myoneural junction) is a junction between nerve and muscle; it is a chemical synapse formed by the contact between the presynaptic terminal of a motor neuron and the postsynaptic membrane of a muscle fiber.he development of the neuromuscular junction requires signaling from both the motor neuron's terminal and the muscle cell's central region. During development, muscle cells produce acetylcholine receptors (AChRs) and express them in the central regions in a process called prepatterning.
Key Concepts: The somatic neuromuscular junction is the site of communication between motor neurons and skeletal muscle fibres. Specialisations of the neuromuscular junction mean that activity in and release of transmitter from motor neurons produces contraction of skeletal muscle fibres rapidly and reliably.he neuromuscular junction comprises four cell types: the motor neuron, terminal Schwann cell, skeletal muscle fibre and kranocyte, with the motor neuron and muscle fibre separated by a gap called the synaptic cleft.