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The key glucocorticoid in humans is cortisone, which is released by the adrenal glands. Cortisone is a glucocorticoid that stimulates the conversion of proteins to glucose in the liver. A glucocorticoid is any one of a group of steroid hormones, such as cortisone, that are produced by the adrenal glands in the kidney and which control carbohydrate, protein, and fat metabolism, and have anti-inflammatory activity.
Natural glucocorticoids are steroid hormones with powerful anti-inflammatory effects produced by the human body. Glucocorticoid drugs are usually synthetic compounds that have anti-inflammatory effects similar to those of natural glucocorticoids.Natural glucocorticoids are produced by the cortex of the adrenal gland.The adrenal glands are organs located immediately above our kidneys (ad = top of, renal = kidney).They are divided into two distinct regions: 1  The adrenal medulla comprises the inner portion of the adrenal gland.atural glucocorticoids are produced by the cortex of the adrenal gland. The adrenal glands are organs located immediately above our kidneys (ad = top of, renal = kidney). They are divided into two distinct regions: 1  The adrenal medulla comprises the inner portion of the adrenal gland.