Pretest-posttest designs grew from the simpler posttest only designs, and address some of the issues arising with assignment bias and the allocation of participants to groups. One example is education, where researchers want to monitor the effect of a new teaching method upon groups of children.
A neuromuscular junction (sometimes called a myoneural junction) is a junction between nerve and muscle; it is a chemical synapse formed by the contact between the presynaptic terminal of a motor neuron and the postsynaptic membrane of a muscle fiber.he development of the neuromuscular junction requires signaling from both the motor neuron's terminal and the muscle cell's central region. During development, muscle cells produce acetylcholine receptors (AChRs) and express them in the central regions in a process called prepatterning.
The term 'motor neuron' is usually restricted to the efferent neurons that actually innervate muscles (the lower motor neurons). A single motor neuron may innervate many muscle fibres and a muscle fibre can undergo many action potentials in the time taken for a single muscle twitch.he interface between a motor neuron and muscle fiber is a specialized synapse called the neuromuscular junction. Upon adequate stimulation, the motor neuron releases a flood of neurotransmitters that bind to postsynaptic receptors and triggers a response in the muscle fiber which leads to muscle movement.