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Quinine is only approved for the treatment of malaria. Tonic water contains quinine but it does not have enough quinine to help with leg cramps. Common side effects associated with quinine can include headache, nausea, diarrhea, vomiting, hives, fever, ringing in the ears, vision problems, and bleeding problems.
The quinine in tonic water causes it to grow bright blue under a black light. Science Photo Library / Getty Images The bitter flavoring of tonic water is due to the presence of quinine, which glows blue-white when placed under a black light. You'll see the glow in both regular and diet tonic water.