Avoid if allergic or sensitive to CoQ10, idebenone, or related substances. CoQ10 is likely safe when up to 3,000 milligrams is taken by mouth daily for up to eight months in healthy people. Nanoparticular CoQ10 is safe at doses of 300 milligrams daily for up to three months.debenone is likely safe in doses of up to 60 milligrams per kilogram daily. Use cautiously in high doses over a long period of time. Use cautiously in high doses in people with liver problems. Doses of greater than 300 milligrams daily may affect levels of liver enzymes.
The recommendation stated that a person should have 1 ml (about 1/5 of a teaspoon) of water for each calorie he or she consumes. The average diet at the time was approximately 1900 calories, meaning you needed about 64 ounces of water per day. Now the Institute of Medicine sets general guidelines for total water intake. It recommends that women consume a total of 91 ounces (thatâs about 2.7 liters) per day â from all food and beverages combined. For men, itâs about 125 ounces a day (or 3.7 liters). Depending on your diet, about 25% of the water you consume comes from your food. Most of us healthy folks get enough water in the foods and liquids we consume. That includes any liquid we drink â even caffeinated beverages like soda, coffee and tea.
There is no evidence that adding the eight cups of water to everything else you drink will do you any good and it could do you harm (American Journal of Physiological-Regulatory, Integrative and Comparative Physiology, November 2002, Drink at least eight glasses of water a day.here is a very well accepted idea that we should drink about eight cups of water per day (two to three litres) in addition to our food and other drinks.