Asker's rating. 1  Shackles are brackets installed on the rear leaf springs it causes the rear of the car to be raised giving the car that classic Muscle look. 2  useing a larger shackle will raise the rear of the car allowing slightly bigger tires in the rear. 3  Shackled Means.
Clinical Significance. A synthetic circular peptide containing citrulline called CCP IgG (cyclic citrullinated peptide) has been found to be better at discriminating Rheumatoid Arthritis patients from other patients than either the perinuclear autoantibody test or the test for rheumatoid factor.
IgG antibodies are important for fighting bacterial and viral infections. IgG antibodies are the only type of antibody that can cross the placenta, therefore the IgG antibodies of a pregnant woman can also help protect her baby in its initial weeks of life before its own immune system has developed.here are five major types of antibodies-IgA, IgG, IgM, IgD and IgE. IgG antibodies are the smallest antibody and are found in all body fluids. They are composed of two heavy chains and two light chains, and each molecule has two antigen binding sites.