1 IgG antibodies are the only type of antibody that can cross the placenta in a pregnant woman to help protect her baby (fetus). 2  IgM. 3  IgM antibodies are the largest antibody. 4  They are found in blood and lymph fluid and are the first type of antibody made in response to an infection.
Lymphedema refers to swelling that generally occurs in one of your arms or legs. Sometimes both arms or both legs swell. Lymphedema is most commonly caused by the removal of or damage to your lymph nodes as a part of cancer treatment. It results from a blockage in your lymphatic system, which is part of your immune system. The blockage prevents lymph fluid from draining well, and the fluid buildup leads to swelling.
Because swelling is sometimes a sign of cancer, it is also important to see your doctor to be sure the cancer has not come back. Causes of lymphedema. Lymphedema is usually a predictable long-term side effect of some cancer treatments. The most common causes of lymphedema in cancer survivors include: Surgery in which lymph nodes were removed. For example, surgery for breast cancer often involves removing 1 or more lymph nodes under the arm to check for cancer. This can cause lymphedema in the arm. Radiation therapy or other causes of inflammation or scarring in the lymph nodes and lymph vessels. Blockage of the lymph nodes and/or lymph vessels by the cancer. The risk of lymphedema increases with the number of lymph nodes and lymph vessels removed or damaged during cancer treatment or biopsies.