The differential should include other causes of hemolysis, such as that found in non-immune hemolytic anemia including intrinsic red cell defects, hemolysis due to extrinsic factors (ie trugs or toxins) as well as mechanical damage hemolytic anemia as found in DIC and HUS.
The best initial antibiotic choice is thought to be a macrolide. Macrolides provide the best coverage for the most likely organisms in community-acquired bacterial pneumonia (CAP). Macrolides have effective coverage for gram-positive, Legionella, and Mycoplasma organisms. Azithromycin administered intravenously is an alternative to intravenous erythromycin.
Beta-lactam antibiotics. The Beta-lactam antibiotics are a broad class of antibiotics that includes the penicillins and the cephalosporins. Ceftriaxone (Rocephin), a cephalosporin, is sometimes given intravenously to patients with Lyme disease.enicillin antibiotics are historically significant because they were the first drugs that were effective against many previously serious diseases such as tuberculosis, syphilis, and staphylococcus infections. Penicillins are still widely used today, though many types of bacteria are now resistant.