The AB Design can be used to quickly assess the effects of an experimental variable. Its main disadvantage its inability to distinguish the experimental effect from possible confounds that might occur coincident with the change of condition.
ceÂ·liÂ·ac disÂ·ease. A disease occurring in children and adults characterized by sensitivity to gluten, with chronic inflammation and atrophy of the mucosa of the upper small intestine; manifestations include diarrhea, malabsorption, steatorrhea, and nutritional and vitamin deficiencies.
Gluten is a protein found in grain products such as bread and pasta. The protein can damage the intestines in patients who are gluten-intolerant. Some people with a sensitivity or intolerance to gluten also experience IBS. In such cases, a gluten-free diet may reduce symptoms.