Asker's rating. 1  Shackles are brackets installed on the rear leaf springs it causes the rear of the car to be raised giving the car that classic Muscle look. 2  useing a larger shackle will raise the rear of the car allowing slightly bigger tires in the rear. 3  Shackled Means.
Clinical Significance. A synthetic circular peptide containing citrulline called CCP IgG (cyclic citrullinated peptide) has been found to be better at discriminating Rheumatoid Arthritis patients from other patients than either the perinuclear autoantibody test or the test for rheumatoid factor.
1 Total Immunoglobulin A Antibody (test code 539) 2  IgA-tTG (test code 8821) 3  If the IgA-tTG is positive, IgA-EMA with Reflex to IgA-EMA Titer (test code 15064) will be performed.  If total IgA concentration is low IgG-tTG antibody test (test code 11070) will be performed.