The AB Design can be used to quickly assess the effects of an experimental variable. Its main disadvantage its inability to distinguish the experimental effect from possible confounds that might occur coincident with the change of condition.
ceÂ·liÂ·ac disÂ·ease. A disease occurring in children and adults characterized by sensitivity to gluten, with chronic inflammation and atrophy of the mucosa of the upper small intestine; manifestations include diarrhea, malabsorption, steatorrhea, and nutritional and vitamin deficiencies.
Non-coeliac gluten sensitivity (gluten intolerance) is a condition arising from a syndrome of gastrointestinal responses to gluten different from the immune response characteristic of coeliac disease. The global prevalence of gluten-related disorders is estimated to be 5%.