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hypo-. A prefix that means beneath or below, as in hypodermic, below the skin. It also means less than normal, as in hypoglycemia, having a level of sugar in the blood that is less than normal.Translations. prefix that means beneath or below, as in hypodermic, below the skin. It also means less than normal, as in hypoglycemia, having a level of sugar in the blood that is less than normal.
The prefix hypo generally means below or under. It is commonly used in anatomy and medicine. Some examples of such words are-hypodermic, hypotension, hypotensive, hypothyroid â¦ ism and hyposulphate. prefix is a syllable (or two) or a word added to a root/base with  that changes the word's meaning. A suffix is at the end.    Example:   Pregame (Pre=before so â¦ before the game)   Countable (able= can so can be counted). + 60 others found this useful.