Made mostly of collagen, bone is living, growing tissue. Collagen is a protein that provides a soft framework, and calcium phosphate is a mineral that adds strength and hardens the framework. This combination of collagen and calcium makes bone strong and flexible enough to withstand stress.
Psychrotrophic bacteria are defined as those that grow at 7Â°C, although their optimal growth temperature is higher. During cold storage after milk collection they dominate the flora, and their extracellular enzymes, mainly proteases and lipases, contribute to the spoilage of dairy products.
Streptococcus pyogenes possesses a wide variety of virulence factors and can cause severe invasive infections. Most S. pyogenes express surface-located fibronectin-binding proteins as major invasion molecules.. Group A Streptococcus pyogenes is an important gram-positive bacterial pathogen that causes a wide variety of clinical conditions, ranging from pharyngitis to severe invasive infections and necrotizing fasciitis. The reported lethality of severe S. pyogenes infections is high, ranging from 10%â30% [1] .