Onii can end with 3 different Japanese honourifics, -San, -Chan, or -Sama. -San is the basic ending for the basic big bro. -Sama is a bit of a formal ending for big brother, nothing too special. I really love my Onii-Chan!
Almost 300 million people suffer from acute malaria each year. 40 % of the worldâs population live in areas with malaria risk. Malaria, seen as a consequence of poverty, is also a major cause of poverty and its prevention is an important part of poverty alleviation.
Malaria facts. 1  More than 198 million cases of malaria occurred worldwide in 2013. 2  The World Health Organization estimates that 600,000-800,000 people died of malaria in 2012; the vast majority are young children in sub-Saharan Africa.