In post-marketing clinical studies, pitavastatin reduced LDL, Total Cholesterol (TC), non-HDL cholesterol and Apolipoprotein B (ApoB) by 26.2-48%, 16.6-37%, 22.5-45%, and 17.4-41%, respectively. Its effects on HDL and triglycerides varied and ranged from -6.9% to 17.8%, and -46% up to an increase of 21%, respectively.
Cats can have their first heat cycle between 4-6 months of age and will go in to heat approximately 3 times a year. Each litter typically has between 4 and 6 kittens. Dogs go into heat at about 4-6 months of age and typically have two heat cycles per year. Each litter has, on average, between 4 and 10 puppies. A dogâs heat cycle lasts a total of 30 days. The vagina will swell during the first 10 days. There will be bloody discharge during the next 10 days.
And certain breedsâlike Siameseâmay go into heat as early as 4 months, while for other breeds 10 months old is a more typical age for going into heat. Signs. When a cat goes into heat, her meow will sound more like a howl and she will be more affectionate toward you, other cats and even the dining room chairs, rubbing against nearly anything and purring loudly.