In post-marketing clinical studies, pitavastatin reduced LDL, Total Cholesterol (TC), non-HDL cholesterol and Apolipoprotein B (ApoB) by 26.2-48%, 16.6-37%, 22.5-45%, and 17.4-41%, respectively. Its effects on HDL and triglycerides varied and ranged from -6.9% to 17.8%, and -46% up to an increase of 21%, respectively.
Cats can have their first heat cycle between 4-6 months of age and will go in to heat approximately 3 times a year. Each litter typically has between 4 and 6 kittens. Dogs go into heat at about 4-6 months of age and typically have two heat cycles per year. Each litter has, on average, between 4 and 10 puppies. A dogâs heat cycle lasts a total of 30 days. The vagina will swell during the first 10 days. There will be bloody discharge during the next 10 days.
When will my dog come into heat? What age will my dog come into her first heat? First heat can vary greatly dog to dog. The youngest is about six months of age though sometimes a female will come into season younger. First heat can start as late as 12 or even 14 months of age or later in rare cases. Again, it can vary dog to dog. How often will my dog come into heat? Again, this varies dog-to-dog â average is every six months but it could be more or less often.