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The result is an increase in the heart rate. Conversely, stimulating the parasympathetic nervous system (vagal nerves to the heart) increases the resting potential and decreases the rate of diastolic depolarization; under these circumstances the heart rate slows. The...
Electrical impulses generated in the SN must then be conducted outside the SN in order to depolarize the rest of the heart. SN activity is regulated by the autonomic nervous system. For example, parasympathetic stimulation causes sinus bradycardia, sinus pauses, or sinoatrial exit block. These actions decrease SN automaticity, thereby decreasing the heart rate. Sympathetic stimulation, on the other hand, increases the slope of phase 4 spontaneous depolarizations.