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Blood disorders can affect any of the three main components of blood: 1  Red blood cells, which carry oxygen to the body's tissues. 2  White blood cells, which fight infections. 3  Platelets, which help blood to clot.
Blood clots are essential to stop bleeding after injury, but harmful blood clots can also form, causing serious damage. Most heart attacks and strokes result from the sudden formation of a blood clot on a cholesterol plaque inside an artery in the heart or brain. When the plaque ruptures suddenly, thrombogenic substances inside the plaque are exposed to blood, triggering the blood clotting process.