A small carriage propelled by a steam turbine powered engine was apparently invented by Ferdinand Verbiest, a Belgian, in 1672 while in China. It is argued that this constitutes the first 'car' ever invented, but the design was only 65cm long, had no seats or pilot controls, and was intended as little more than a toy.
In bipolar disorder, mixed state is a condition during which symptoms of both mania and depression occur simultaneously. Individuals experiencing a mixed state may have manic symptoms such as grandiose thoughts while simultaneously experiencing depressive symptoms such as excessive guilt or feeling suicidal.
Treatments for Bipolar Disorder. Bipolar disorder is a lifelong condition, so it requires lifelong treatment, even when the affected person feels fine. Treatment is usually guided by a psychiatrist or other mental health professional skilled in treating bipolar disorder. Treatment may include a combination of medication, therapy, and other treatments that may be necessary, such as rehabilitation from substance abuse.