Tetanus is also commonly called lockjaw, because the infection primarily causes muscle contractions in the jaw and neck, but can eventually spread to other parts of the body. Without treatment, tetanus infection can be life-threatening.
Competitive inhibitors. The inhibitor (I) competes with the substrate (S) for the enzyme active site (also known as the S-binding site). Binding of either of these molecules in the active site is a mutually exclusive event. The substrate and inhibitor share a high degree of structural similarity.
1 This binding to an allosteric site changes the conformation of the enzyme so that the affinity of the substrate for the active site is reduced. 2  These inhibitors lower the K m and V m. 3  File:Uncompetitive inhibition.docx. 4  mixed inhibition the inhibitors can bind to the enzyme at the same time as the enzyme substrate.