Tetanus is also commonly called lockjaw, because the infection primarily causes muscle contractions in the jaw and neck, but can eventually spread to other parts of the body. Without treatment, tetanus infection can be life-threatening.
Competitive inhibitors. The inhibitor (I) competes with the substrate (S) for the enzyme active site (also known as the S-binding site). Binding of either of these molecules in the active site is a mutually exclusive event. The substrate and inhibitor share a high degree of structural similarity.
The binding of an inhibitor can stop a substrate from entering the enzyme's active site and/or hinder the enzyme from catalyzing its reaction. Inhibitor binding is either reversible or irreversible. Irreversible inhibitors usually react with the enzyme and change it chemically (e.g. via covalent bond formation).n enzyme inhibitor is a molecule that binds to an enzyme and decreases its activity.