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A gene mutation is a permanent alteration in the DNA sequence that makes up a gene, such that the sequence differs from what is found in most people.Mutations range in size; they can affect anywhere from a single DNA building block (base pair) to a large segment of a chromosome that includes multiple genes. gene mutation is a permanent alteration in the DNA sequence that makes up a gene, such that the sequence differs from what is found in most people.
exists and is an alternate of. Merge this question into. Split and merge into it. Answer by Milym32696. Confidence votes 217. A gene mutation is a permanent change in the DNA sequence, that makes up a gene. Mutations range in size, from a single DNA building block (DNA base), to a large segment of a chromosome.enetic mutations are not always harmful. A lot of mutations have a positive effect on the host. Some genetic mutations may help the host endure certain conditions in the envi â¦ ronment, or eat certain food, or resist a certain superbug or virus, etc etc. However, some mutations can be harmful.