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There is much debate about the amount of saliva that is produced in a healthy person per day; estimates range from 0.75 to 1.5 litres per day while it is generally accepted that during sleep the amount drops to nearly zero.
Saliva is secreted by the serous and the mucus cells in the salivary glands. One liter of saliva is secreted from these glands every day. : The most common disease to affect the salivary glands is salivary duct calculus, which is the formation of calcified deposits or stones in the salivary glands.