In post-marketing clinical studies, pitavastatin reduced LDL, Total Cholesterol (TC), non-HDL cholesterol and Apolipoprotein B (ApoB) by 26.2-48%, 16.6-37%, 22.5-45%, and 17.4-41%, respectively. Its effects on HDL and triglycerides varied and ranged from -6.9% to 17.8%, and -46% up to an increase of 21%, respectively.
Cats can have their first heat cycle between 4-6 months of age and will go in to heat approximately 3 times a year. Each litter typically has between 4 and 6 kittens. Dogs go into heat at about 4-6 months of age and typically have two heat cycles per year. Each litter has, on average, between 4 and 10 puppies. A dogâs heat cycle lasts a total of 30 days. The vagina will swell during the first 10 days. There will be bloody discharge during the next 10 days.
Ideally, your dog should be spayed before she enters her first heat cycle. When Does A Dog Experience Her First Estrus? First estrus generally occurs when an unspayed female dog is between six and 24 months old. It tends to occur earlier for small-breed dogs and later for large-breed dogs. How Often Do Dogs Go Into Heat? Although it varies with different breeds and individual dogs, an unspayed female usually goes into heat twice yearly, about every six months. How Long Does a Dog Stay in Heat? The time during which male dogs are attracted to a female dog is variable, approximately 18 days. However, females are receptive to males for only about half of this time. How Can I Tell if My Dog Is In Heat? During estrus, your female dog may appear nervous, easily distracted and more alert than usual.