In October, the sun shines for at least 7 hours per day but brace yourself for rain as there are on average 6 days of rainfall during the month. Around 70mm of rain falls throughout October with temperatures generally settling between 14 Â°C and 26 Â°C.
For example, ATP allosterically inhibits phosphofructokinase, but it activates the functionally opposite enzyme fructose-1,6-bisphosphatase (see slide 7.5.3). Similarly, phosphorylation inhibits glycogen synthase but activates glycogen phosphorylase, which degrades glycogen (slide 8.4.1).llosteric regulation of phosphofructokinase by AMP. To accomplish the stimulation of phosphofructokinase, AMP interacts with the enzyme at an allosteric binding site, that is, a site that is distant and functionally distinct from the active site.
As a phosphoprotein phosphatase, insulin dephosphorylates the enzyme, thus activating the PFK-2 and inhibiting the FBPase-2 activities. With additional Fru-2,6- P 2 present, activation of PFK-1 occurs to stimulate glycolysis while inhibiting gluconeogenesis.he breakdown of Fru-2,6- P 2 is catalyzed by dephosphorylation by FBPase-2 to produce Fructose 6-phosphate and P i.