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The result is an increase in the heart rate. Conversely, stimulating the parasympathetic nervous system (vagal nerves to the heart) increases the resting potential and decreases the rate of diastolic depolarization; under these circumstances the heart rate slows. The...
An exciting development is the possible application of deep brain stimulation (DBS) to Parkinson-plus syndromes. In an open label trial, Stefani et al reported an improvement in gait and balance in patients with PSP undergoing DBS with the pedeculopontine nucleus and the subthalamic nucleus in combination.