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Enteroendocrine cells of the intestine are the most numerous endocrine cells of the body. They constitute an enteric endocrine system as a subset of the endocrine system just as the enteric nervous system is a subset of the nervous system.
Enteroendocrine cells of the intestine are the most numerous endocrine cells of the body. In a sense they are known to act as chemoreceptors, initiating digestive actions and detecting harmful substances and initiating protective responses.hey produce gastrointestinal hormones or peptides in response to various stimuli and release them into the bloodstream for systemic effect, diffuse them as local messengers, or transmit them to the enteric nervous system to activate nervous responses.