Adult Studies: In a double-blind study of three different dosing regimens of ZOFRAN Injection, 0.015 mg/kg, 0.15 mg/kg, and 0.30 mg/kg, each given three times during the course of cancer chemotherapy, the 0.15-mg/kg dosing regimen was more effective than the 0.015-mg/kg dosing regimen.
Peristaltic movement comprises relaxation of circular smooth muscles, then their contraction behind the chewed material to keep it from moving backward, then longitudinal contraction to push it forward. Earthworms use a similar mechanism to drive their locomotion, and some modern machinery imitates this design.
Peristalsis. Food is moved through the digestive system by a process called peristalsis. Two sets of muscles in the gut wall are involved: 1  circular muscles-which reduce the diameter of the gut when they contract. 2  longitudinal muscles-which reduce the length of the gut when they contract.