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Blood disorders can affect any of the three main components of blood: 1  Red blood cells, which carry oxygen to the body's tissues. 2  White blood cells, which fight infections. 3  Platelets, which help blood to clot.
Bleeding disorders often develop when the blood canât clot properly. For blood to clot, your body needs blood proteins called clotting factors and blood cells called platelets. Normally, platelets clump together to form a plug at the site of a damaged or injured blood vessel.