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Blood disorders can affect any of the three main components of blood: 1  Red blood cells, which carry oxygen to the body's tissues. 2  White blood cells, which fight infections. 3  Platelets, which help blood to clot.
Plaques that rupture cause blood clots to form that can block blood flow or break off and travel to another part of the body. This is called an embolism. 1  If a blood clot blocks a blood vessel that feeds the heart, it causes a heart attack.  If a blood clot blocks a blood vessel that feeds the brain, it causes a stroke.