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Causes of Pyogenic Granuloma. A pyogenic granuloma often occurs in areas of previous trauma including acne cysts. It is believed that this lesion is formed when capillary blood vessels start growing rapidly in response to trauma to the skin. These growths mostly occur after injuries, but the reason for this isnât known.
Pyognic Granuloma Causes. These lesions are caused by the growth of many small blood vessels. It may be several cm or up to one inch in diameter. They may be found almost anywhere on the skin as well as even on the gums in the mouth. The cause is unknown. They develop often after some sort of trauma.