A small carriage propelled by a steam turbine powered engine was apparently invented by Ferdinand Verbiest, a Belgian, in 1672 while in China. It is argued that this constitutes the first 'car' ever invented, but the design was only 65cm long, had no seats or pilot controls, and was intended as little more than a toy.
In bipolar disorder, mixed state is a condition during which symptoms of both mania and depression occur simultaneously. Individuals experiencing a mixed state may have manic symptoms such as grandiose thoughts while simultaneously experiencing depressive symptoms such as excessive guilt or feeling suicidal.
Signs and Symptoms of Bipolar Disorder. Bipolar Depression Refers to the âLowsâ of Bipolar Disorder. Bipolar depression is the depressive phase of a larger condition called âbipolar disorder.â It is a tough condition to diagnose. In fact, it could take up to 10 years for people to get an accurate diagnosis. Knowing the signs and symptoms of bipolar depression may help you and your doctor arrive at the correct diagnosis.