Tetanus is also commonly called lockjaw, because the infection primarily causes muscle contractions in the jaw and neck, but can eventually spread to other parts of the body. Without treatment, tetanus infection can be life-threatening.
Competitive inhibitors. The inhibitor (I) competes with the substrate (S) for the enzyme active site (also known as the S-binding site). Binding of either of these molecules in the active site is a mutually exclusive event. The substrate and inhibitor share a high degree of structural similarity.
Noncompetitive inhibitor binds to other site that is not active site of enzyme that changes structure of enzyme; therefore, blocks enzyme binding to substrate that stops enzyme activity and decreases rate of chemical reaction of enzyme and substrate, which can not be changed by increasing concentration of substrate; the binding decreases Vmax and not changes Km of the chemical reaction.