In post-marketing clinical studies, pitavastatin reduced LDL, Total Cholesterol (TC), non-HDL cholesterol and Apolipoprotein B (ApoB) by 26.2-48%, 16.6-37%, 22.5-45%, and 17.4-41%, respectively. Its effects on HDL and triglycerides varied and ranged from -6.9% to 17.8%, and -46% up to an increase of 21%, respectively.
Cats can have their first heat cycle between 4-6 months of age and will go in to heat approximately 3 times a year. Each litter typically has between 4 and 6 kittens. Dogs go into heat at about 4-6 months of age and typically have two heat cycles per year. Each litter has, on average, between 4 and 10 puppies. A dogâs heat cycle lasts a total of 30 days. The vagina will swell during the first 10 days. There will be bloody discharge during the next 10 days.
Estrus (heat) is the mating period of female animals. When estrus occurs, animals are said to be in heat or in season.. Dogs generally have their first estrous cycle at 6-12 months of age. Some females of the large breeds, however, may not have their first estrus until they are 12-24 months of age.hen estrus occurs, animals are said to be in heat or in season.. Dogs generally have their first estrous cycle at 6-12 months of age. Some females of the large breeds, however, may not have their first estrus until they are 12-24 months of age.