A small carriage propelled by a steam turbine powered engine was apparently invented by Ferdinand Verbiest, a Belgian, in 1672 while in China. It is argued that this constitutes the first 'car' ever invented, but the design was only 65cm long, had no seats or pilot controls, and was intended as little more than a toy.
In bipolar disorder, mixed state is a condition during which symptoms of both mania and depression occur simultaneously. Individuals experiencing a mixed state may have manic symptoms such as grandiose thoughts while simultaneously experiencing depressive symptoms such as excessive guilt or feeling suicidal.
Most people with bipolar disorder spend more time with depressive symptoms than manic or hypomanic symptoms. What Are the Symptoms of Bipolar Disorder? In bipolar disorder, the dramatic episodes of high and low moods do not follow a set pattern. Someone may feel the same mood state (depressed or manic) several times before switching to the opposite mood.