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Enteroendocrine cells of the intestine are the most numerous endocrine cells of the body. They constitute an enteric endocrine system as a subset of the endocrine system just as the enteric nervous system is a subset of the nervous system.
Cells of the stomach. Parietal cells (also called oxyntic cells) are the stomach epithelium cells which secrete gastric acid. Parietal cells produce gastric acid (hydrochloric acid) in response to histamine (via H2 receptors), acetylcholine (M3 receptors) and gastrin (gastrin receptors). Parietal cells contain an extensive secretory network (called canaliculi) from which the HCl is secreted by active transport into the stomach.