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The result is an increase in the heart rate. Conversely, stimulating the parasympathetic nervous system (vagal nerves to the heart) increases the resting potential and decreases the rate of diastolic depolarization; under these circumstances the heart rate slows. The...
Abundant evidence links sympathetic nervous system activation to outcomes of patients with heart failure (HF). 1 In contrast, parasympathetic activation has complex cardiovascular effects that are only beginning to be recognized.uscarinic receptors are abundant on sinoatrial and atrioventricular nodal cells. The known effects of the parasympathetic nervous system on cardiac function, heart rate, and atrioventricular nodal conduction appear modulated generally via M 2 receptors.