Adult Studies: In a double-blind study of three different dosing regimens of ZOFRAN Injection, 0.015 mg/kg, 0.15 mg/kg, and 0.30 mg/kg, each given three times during the course of cancer chemotherapy, the 0.15-mg/kg dosing regimen was more effective than the 0.015-mg/kg dosing regimen.
Peristaltic movement comprises relaxation of circular smooth muscles, then their contraction behind the chewed material to keep it from moving backward, then longitudinal contraction to push it forward. Earthworms use a similar mechanism to drive their locomotion, and some modern machinery imitates this design.
Where Does Peristalsis Occur. Peristalsis occurs throughout the digestive tract. It begins with the primary peristaltic wave in the esophagus as you swallow food from your mouth to the stomach. As food enters your stomach these muscular movements continue right through to your anus, where waste is eliminated from the body.