Females are usually carriers because they only have one copy of the disease allele. Affected males are related through carrier females. For a carrier female, with each pregnancy there is a one in two (50%) chance her sons will inherit the disease allele and a one in two (50%) chance her daughters will be carriers.
A complimentary close, also known as a complimentary closing, is the term prior to your signature in an email message or formal letter. This sign-off phrase shows your respect and appreciation for the person who is considering the request in your letter or email.
If your letter does that but itâs longer than a page, look for ways to edit it down without losing its essence. If itâs half a page or less, you should just be damn sure that itâs truly passing that litmus test. Itâs hard to meet that test if youâre writing very short. Not impossible, but a lot harder.