Disclosure in Annual Financial Statements. If an estimate is disclosed in an interim period and that estimate is significantly changed in the final interim period (where there is no publishing of an interim report - which is usually the case), then the change in estimate is disclosed in the annual report.
The PenFill cartridge that you are currently using can be kept at room temperature up to 42 days, as long as they are kept below 86 degrees F (30 degrees C). Throw away unrefrigerated disposable Levemir PenFill cartridges after 42 days from the cartridges first use, even if it still contains Levemir.
It depends on how many units you are using. I usually get about 2 1/2 weeks out of a pen including the 2 units to prime each time. I mark on my calendar each time I take one out of the fridge for 28 days, that's how long they are supposed to be good for, and I always have time left on the 28 day count, so I start all over again with a new pen!