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DHEA supplementation can increase testosterone levels quite significantly in middle-aged and older men, and in menopausal women. However, these effects are â for some reason â highly unreliable in younger guys.
DHEA levels are lower in women who have lupus (an autoimmune disorder that affects the skin and organs). DHEA may boost immune function. Several trials report that DHEA may lack an effect on SLE disease activity, though there is some evidence supporting its use in addition to regular treatment.