The most common cause of vascular obstruction is a blood clot, also known as a DVT. This type of vascular problem usually occurs in one leg (not both), and leads to swelling of the soft tissues throughout the foot and ankle. The swelling can also extend further up the leg.
The hypothalamus is a part of your brain that controls body temperature. When you exercise, your body temperature increases, causing the hypothalamus to signal the brainstem to further increase your heart rate.
Resting heart rate reflects the activity of the autonomic nervous system and hormone levels as well as heart fitness, he said. Increased activity of the autonomic nervous system and higher hormone levels can contribute to the start and progression of heart disease, Fonarow said.