5. Summary & Conclusions CBEA is a key element of enterprise systems engineering; it is the analytical framework that supports capabilities-based planning, programming, and acquisition in a systemic approach to the purposeful evolution of the enterprise.
The genes of telomerase subunits, which include TERT, TERC, DKC1 and TEP1, are located on different chromosomes. The human TERT gene (hTERT) is translated into a protein of 1132 amino acids. TERT polypeptide folds with (and carries) TERC, a non-coding RNA (451 nucleotides long).
Telomeres are buffer regions of non-coding DNA at the ends of chromosomes that prevent the loss of protein-coding DNA when cells divide. Telomeres get slightly shorter each time a chromosome replicates during cell division, but stress can also cause them to shorten. Shorter telomeres are associated with a raft of diseases in adults from diabetes to dementia.