Females are usually carriers because they only have one copy of the disease allele. Affected males are related through carrier females. For a carrier female, with each pregnancy there is a one in two (50%) chance her sons will inherit the disease allele and a one in two (50%) chance her daughters will be carriers.
A complimentary close, also known as a complimentary closing, is the term prior to your signature in an email message or formal letter. This sign-off phrase shows your respect and appreciation for the person who is considering the request in your letter or email.
2. Write the date in the upper right corner. 3. Start the letter off by writing 'Dear Mr. or Mrs. ________, This is a personal letter, so you want to end the salutation with a comma. 1  You can be more informal if your teacher will find it appropriate. You can be more informal if your teacher will find it appropriate. 2  For example, if you call your teacher Coach Sue, then call her Coach Sue in the salutation. 3  Avoid calling your teacher by his or her first name unless you are truly on a first-name basis.