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Automated fraction collector and sampler for chromatographic techniques. Column chromatography in chemistry is a method used to purify individual chemical compounds from mixtures of compounds. It is often used for preparative applications on scales from micrograms up to kilograms.
Desalting columns use the principle of size exclusion chromatography, also called gel filtration chromatography. In addition to desalting, the other main use for size exclusion chromatography is size fractionation. The matrix beads in a size exclusion column contain pores.