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murine. 1  adj of or relating to or transmitted by a member of the family Muridae (rats and mice) 2  n a rodent that is a member of the family Muridae.
Freebase (0.00 / 0 votes) Rate this definition: Murinae. The Old World rats and mice, part of the subfamily Murinae in the family Muridae, comprise at least 519 species. This subfamily is larger than all mammal families except the Cricetidae and Muridae, and is larger than all mammal orders except the bats and the remainder of the rodents.