The Costa Concordia was only hours into a cruise of the Mediterranean on Friday 13 January 2012 when disaster struck just off Giglio island. The huge vessel - which had more than 4,000 passenger and crew onboard - then lost power, drifted and partially capsized.
The recommended dose range for metoprolol [succinate] for treating hypertension in adults is 25 to 100 mg once a day. The recommended dose range for metoprolol [succinate] for treating hypertension in children (6 years of age or older) is 0.1 mg/kg to 50 mg once a day.
DUTOPROL 25/12.5 contains 23.75 mg of metoprolol succinate extended release equivalent to 25 mg. of metoprolol tartrate and 12.5 mg of hydrochlorothiazide. DUTOPROL 50/12.5 contains 47.5 mg of. metoprolol succinate extended release equivalent to 50 mg of metoprolol tartrate and 12.5 mg of. hydrochlorothiazide. DUTOPROL 100/12.5 contains 95 mg of metoprolol succinate extended release. equivalent to 100 mg of metoprolol tartrate and 12.5 mg of hydrochlorothiazide.