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Automated fraction collector and sampler for chromatographic techniques. Column chromatography in chemistry is a method used to purify individual chemical compounds from mixtures of compounds. It is often used for preparative applications on scales from micrograms up to kilograms.
One difference between column and thin layer chromatography is that  in column chromatography the stationary phase is powdered adsorbent  placed in a vertical glass column. â¦In thin lay chromatography, the  stationary phase is also powdered adsorbent, but it is fixed to a  plate made from glass, aluminum, or plastic.