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Medical Definition of Toxicity. Toxicity: The degree to which a substance (a toxin or poison) can harm humans or animals. Acute toxicity involves harmful effects in an organism through a single or short-term exposure. Subchronic toxicity is the ability of a toxic substance to cause effects for more than one year but less than the lifetime of the exposed organism.
One of these naturally occuring poisons is called saxitoxin, reported to be one of the most toxic non-protein substances known. The LD50 in mice is approximately 8 microgram/kg which means that a single dose of 0.2 milligram would prove fatal for the average weight human.