February 12, 2011 - Track & Field Menâs and Womenâs Track and Field Top Yale, Fall to Princeton at HYP Meet In its final meet before the Heptagonal Championships, the Harvard track and field team turned in a pair of second-place finishes at the annual HYP...
An Okazaki fragment is a relatively short fragment of DNA (with an RNA primer at the 5' terminus) created on the lagging strand during DNA replication. It was originally discovered in 1968 by Reiji Okazaki, Tsuneko Okazaki, and their colleagues while studying replication of bacteriophage DNA in Escherichia coli.
Copying occurs at a localized region called the replication fork, which is a Y shaped structure where new DNA strands are synthesised by a multi-enzyme complex. Here the DNA to be copied enters the complex from the left.One new strand is leaving at the top of frame and the other new strand is leaving at bottom.The first step in DNA replication is the separation of the two strands by an enzyme called helicase.he other half of the DNA double helix, known as the lagging strand, has the opposite 3' to 5' orientation and consequently requires a more complicated copying mechanism. As it emerges from the helicase, the lagging strand is organised into sections called Okazaki fragments.