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By Mayo Clinic Staff. Doctors don't know what causes polycystic ovary syndrome, but these factors may play a role: Excess insulin. Insulin is the hormone produced in the pancreas that allows cells to use sugar (glucose) â your body's primary energy supply. If you have insulin resistance, your ability to use insulin effectively is impaired, and your pancreas has to secrete more insulin to make glucose available to cells.
, and as a result, an increased risk of. disease. The syndrome is generally characterized by the presence of polycystic ovaries, hyperandrogenism (the condition caused by excess male hormones or male-like traits) and irregular ovulation and menstruation.The symptoms of PCOS can vary.any, but not all, women with PCOS will have the polycystic-looking ovaries (which are often two to five times larger than normal ovaries) for which the syndrome is named, but it is possible to be diagnosed with the syndrome without having this sign. And not all women with polycystic-appearing ovaries will have PCOS.