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Medical Definition of Toxicity. Toxicity: The degree to which a substance (a toxin or poison) can harm humans or animals. Acute toxicity involves harmful effects in an organism through a single or short-term exposure. Subchronic toxicity is the ability of a toxic substance to cause effects for more than one year but less than the lifetime of the exposed organism.
Lead is toxic to humans, and poisoning can occur either through ingestion of lead or by breathing in lead dust. Both long-term low-dose and short-term high-dose exposure can permanently damage the nervous, renal (kidney), and hematopoietic (blood-forming) systems.