5. Summary & Conclusions CBEA is a key element of enterprise systems engineering; it is the analytical framework that supports capabilities-based planning, programming, and acquisition in a systemic approach to the purposeful evolution of the enterprise.
The genes of telomerase subunits, which include TERT, TERC, DKC1 and TEP1, are located on different chromosomes. The human TERT gene (hTERT) is translated into a protein of 1132 amino acids. TERT polypeptide folds with (and carries) TERC, a non-coding RNA (451 nucleotides long).
Untreated Depression and Shortened Telomeres Untreated depression creates biological changes that accelerate aging and increase the risk of life-threatening diseases. Major Depressive Disorder (MDD) can shorten the length of telomeres. A team led by Owen Wolkowitz, MD, professor of psychiatry at UC San Francisco (UCSF) has been studying the biological link between chronic depression and an enzyme called telomerase which is linked to shorter telomeres.