February 12, 2011 - Track & Field Menâs and Womenâs Track and Field Top Yale, Fall to Princeton at HYP Meet In its final meet before the Heptagonal Championships, the Harvard track and field team turned in a pair of second-place finishes at the annual HYP...
An Okazaki fragment is a relatively short fragment of DNA (with an RNA primer at the 5' terminus) created on the lagging strand during DNA replication. It was originally discovered in 1968 by Reiji Okazaki, Tsuneko Okazaki, and their colleagues while studying replication of bacteriophage DNA in Escherichia coli.
1 The separation of the two single strands of DNA creates a âYâ shape called a replication âforkâ. 2  The two separated strands will act as templates for making the new strands of DNA. 3  One of the strands is oriented in the 3â to 5â direction (towards the replication fork), this is the leading strand. Chunks of DNA, called Okazaki fragments, are then added to the lagging strand also in the 5â to 3â direction. 2  This type of replication is called discontinuous as the Okazaki fragments will need to be joined up later.