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The recommended starting dose when treating depression is mirtazapine 15 mg, taken once daily at bedtime. Your healthcare provider may increase the dosage if symptoms continue, or decrease the dose if side effects occur.The maximum recommended dose of mirtazapine is 45 mg per day.he recommended starting dose when treating depression is 15 mg, taken once a day. The dose of mirtazapine (Remeron Â®) that your healthcare provider prescribes will vary, depending on a number of factors, including:
Mirtazapine is an antidepressant medication that works in the brain. It is approved for the treatment of major depressive disorder (MDD). Symptoms of depression include: 1  Depressed mood-feeling sad, empty, or tearful.2  Feeling worthless, guilty, hopeless, and helpless. 3  Loss of interest or pleasure in your usual activities.irtazapine is usually taken 1 time per day at bedtime with or without food. Typically patients begin at a low dose of medicine and the dose is increased slowly over several weeks. The dose usually ranges from 15 mg to 45 mg. Only your healthcare provider can determine the correct dose for you.