They observed that delivering the immunization via the rectum was most effective and that mice that received the vaccine had significantly lower levels of C. difficile colonization.(28) (1)Kelly, C.P., LaMont, J.T. âClostridium difficile infectionâ.
Happy holidays: Booking five weeks in advance is the optimal time for cheap flights, says the study. The answer is - domestic flights are at their cheapest 54 days before takeoff, which could save travellers up to Â£190. While the worst time to book a cheap flight is last minute - with the day before departure the most expensive.
That brings us to the 54 days. For a study published in February, the booking site CheapAir.com looked at millions of trip combinations, searching as far as 320 days in advance to one day prior to departure and every possible day between. Thatâs 1.3 billion airfares. The result: 54 days in advance was the best time, on average, to buy domestic tickets. This is not a hard-and-fast rule, however. Airfares to popular vacation destinations tend to go up sooner.