United States Federal Sentencing Guidelines. The Federal Sentencing Guidelines are rules that set out a uniform sentencing policy for individuals and organizations convicted of felonies and serious (Class A) misdemeanors in the United States federal courts system. The Guidelines do not apply to less serious misdemeanors.
translocation (tranz-loh-kay-shÅn) n. (in genetics) a type of chromosome mutation in which part of a chromosome is transferred to another part of the same chromosome or to a different chromosome. This can lead to serious genetic disorders, e.g. chronic myeloid leukaemia.
The third form, translocation Down syndrome, occurs when the extra chromosome in the 21 pair breaks off and attaches itself to another chromosome. Translocation Down syndrome is the only form that may be inherited. A parent who possesses a balanced translocationâa chromosome rearrangement with no extra genetic material from chromosome 21âcan pass the translocation to an offspring. Carriers of balanced translocations do not have signs or symptoms of the disorder.