A number of diseases may cause hiccups that can occur at any time of the day, including during sleep. Hiccups may occur with many brain disorders, including strokes, brain tumors, multiple sclerosis, Parkinson disease or brain injuries.
Ads During 'The Big Bang Theory' Are the Most Expensive. The most expensive 30-second TV spot to buy this fall is during CBS' The Big Bang Theory. It costs $326,260 per half-minute commercial aired during the show, more than $50,000 more than during the next most expensive show, The Voice. See also: 6 Great Alternatives to Netflix.
Well, get a bunch of old ad men gathered around the camp fire and they will all tell you that ineffective advertising is the most expensive. The reason is that it is extraordinarily easy to create ineffective ads and extraordinarily difficult to create ones that accomplish defined goals.