Angioedema is caused by an allergic reaction to something you've eaten, an insect bite, pollen allergies, or a medication you've taken. 1  It causes a swelling of the lips, face, and tongue, which usually occurs rapidly. It can also sometimes be accompanied by redness or bumps (hives). Due to the swelling, you may have difficulty talking. Angioedema can also cause swelling of the airway and difficulty breathing, which may be life-threatening.
holocentric chromosome. (genetics). A chromosome with centromer; activity/spread along its entire length.1  Facebook.olocentric chromosome. (genetics). A chromosome with centromer; activity/spread along its entire length. 1  Facebook.
With holocentric chromosomes, the entire length of the chromosome acts as the centromere. Examples of this type of centromere can be found scattered throughout the plant and animal kingdoms, with the most well known example being the nematode Caenorhabditis elegans.n a normal human karyotype, two chromosomes are considered metacentric: chromosomes 1 and 3. In some cases, a metacentric chromosome is formed by balanced translocation: the fusion of two acrocentric chromosomes to form one metacentric chromosome.