The site of the plaque determines the type of heart disease: 1  Coronary artery disease is the build-up of plaque in the arteries supplying blood to the heart. 2  Peripheral artery disease is the build-up of plaque in the arteries supplying blood to the arms and legs.
At a price of $2,000 to $10,000 a pound, saffron is far and away the most expensive food on earth, way more than truffles, caviar, and real balsamic vinegar. Its history is epic; its flavor is revered. International organizations employ lab equipment to fuss over grading crops for flavor, color, and richness.
To avoid saffron poisoning or toxicity, do not take therapeutic doses of saffron in excess of 5 g daily, the website Drugs.com advises. Usually, saffron poisoning symptoms arise after you take more than 5 g in a single dose. Saffron is lethal if taken as a 20 g dose.