5. Summary & Conclusions CBEA is a key element of enterprise systems engineering; it is the analytical framework that supports capabilities-based planning, programming, and acquisition in a systemic approach to the purposeful evolution of the enterprise.
The genes of telomerase subunits, which include TERT, TERC, DKC1 and TEP1, are located on different chromosomes. The human TERT gene (hTERT) is translated into a protein of 1132 amino acids. TERT polypeptide folds with (and carries) TERC, a non-coding RNA (451 nucleotides long).
Premature ageing can be reversed by reactivating an enzyme that protects the tips of chromosomes, a study in mice suggests. Mice engineered to lack the enzyme, called telomerase, become prematurely decrepit. But they bounced back to health when the enzyme was replaced. The finding, published online today in Nature, hints that some disorders characterized by early ageing could be treated by boosting telomerase activity.