GangotriÂ© afateev/FotoliaThe Ganges rises in the southern Great Himalayas on the Indian side of the border with the Tibet Autonomous Region of China. Its five headstreamsâthe Bhagirathi, the Alaknanda, the Mandakini, the Dhauliganga, and the Pindarâall rise in the mountainous region of northern Uttarakhand state.
The signs of ototoxicity, in order of frequency, are: 1 â Development of tinnitus in one or both ears. 2 â Intensification of existing tinnitus or the appearance of a new sound. 3 â Fullness or pressure in the ears other than being caused by infection. 4 â Awareness of hearing loss in an unaffected ear or the progression of an existing loss. 5 â Development of vertigo or a spinning sensation usually aggravated by motion which may or may not be accompanied by nausea.
Oto = ear; toxicity = poisoning. Ototoxicity is, quite simply, ear poisoning (oto = ear, toxicity = poisoning), which results from exposure to drugs or chemicals that damage the inner ear or the vestibulo-cochlear nerve (the nerve sending balance and hearing information from the inner ear to the brain).he occurrence and degree of inner ear poisoning depends upon the drug involved as well as other factors such as heredity. Ototoxicity can be temporary or permanent. The effect of certain drugs is often temporary, while other drugs typically produce permanent changes to the ear.