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Which fact is most important in explaining how enzymes speed reactions? Very low potential energy tends to make molecules unstable. High-energy collisions are less common than low-energy collisions. It takes less energy to break a hydrogen bond than a covalent bond. Large molecules collide more energetically than small molecules. Every reaction step adds to the time required for the overall reaction. Study Enzyme Activity.
In one example, the end product depends on the successful completion of five reactions, each mediated by a specific enzyme. The enzymes in a series can be located adjacent to each other (in an organelle or in the membrane of an organelle), thus speeding the reaction process.any enzymes function by lowering the activation energy of reactions. By bringing the reactants closer together, chemical bonds may be weakened and reactions will proceed faster than without the catalyst. The use of enzymes can lower the activation energy of a reaction (Ea).