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In summary, the new oral anticoagulants represent a giant step forward in the quest to replace warfarin. In addition to their enhanced convenience, the new agents are not only safer than warfarin because of the reduced risk of intracranial bleeding, but they also have the potential to be more effective.
XARELTOÂ® also has fewer drug-drug interactions than warfarin. But like all blood thinners, you have a higher risk of bleeding if you take XARELTOÂ® with other medicines, like aspirin, NSAIDs, warfarin, heparin or clopidogrel, that increase your risk of bleeding.