Lewy body disease is caused by the degeneration and death of nerve cells in the brain. The name comes from the presence of abnormal spherical structures, called Lewy bodies, which develop inside nerve cells. It is thought that these may contribute to the death of the brain cells.
Osteoarthritis can range from mild to severe. The pain associated with osteoarthritis can be significant and it usually is made worse by movement. Osteoarthritis can be limited to one joint or start in one joint usually the knee, hip, hand, foot or spine or it can involve a number of joints.
Osteoarthritis of the knee is very common. This is probably because your knee has to take extreme stresses, twists and turns. Osteoarthritis can affect the main surfaces of your knee joint and also the cartilage underneath your kneecap (patella).1  Youâre most likely to feel pain at the front and sides of your knee.steoarthritis of the knee is very common. This is probably because your knee has to take extreme stresses, twists and turns. Osteoarthritis can affect the main surfaces of your knee joint and also the cartilage underneath your kneecap (patella). 1  Youâre most likely to feel pain at the front and sides of your knee.