One immunotherapy approach is to block the ability of certain proteins, called immune checkpoint proteins, to limit the strength and duration of immune responses. These proteins normally keep immune responses in check by preventing overly intense responses that might damage normal cells as well as abnormal cells.
Deborah Sampson in the Revolutionary War: In the winter of 1781, Sampson began feeling restless and wanted to travel and explore other pursuits. Knowing that her options as a young woman were limited, she came up with the idea of cross-dressing as a man and sought out the advice of a fortune-teller to get some insight into her future, according to her biography The Female Review:
Some wore their finest suits of clothing, while many others wore their work clothes. The clothing worn by the Patriots during the first year of the American Revolution was simply a cross section of the different fashions and styles of civilian clothing worn by New Englanders with all levels of society being represented.