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H emoglobin diseases are a group of blood disorders passed down through families in which there is an abnormal production or structure of the hemoglobin protein.
The hemoglobin test may be ordered during a general health examination or when a person has signs and symptoms of a condition affecting red blood cells such as anemia or polycythemia. Some signs and symptoms of anemia include: 1  Weakness or fatigue. hemoglobin test may be used to: 1  Screen for, diagnose, and measure the severity of anemia (low RBCs, hemoglobin and hematocrit) or polycythemia (high RBCs, hemoglobin and hematocrit).