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Deletion on a chromosome. In genetics, a deletion (also called gene deletion, deficiency, or deletion mutation) (sign: Î´) is a mutation (a genetic aberration) in which a part of a chromosome or a sequence of DNA is lost during DNA replication.Any number of nucleotides can be deleted, from a single base to an entire piece of chromosome. ' Terminal Deletion' â a deletion that occurs towards the end of a chromosome. 2  Intercalary Deletion / Interstitial Deletion â a deletion that occurs from the interior of a chromosome. 3  Microdeletion â a relatively small amount of deletion (up to 5Mb that could include a dozen genes).
Chromosomes are made up mostly of DNA and are the structures in each of the bodyâs cells that carry the genetic information (in the form of genes) that tells the body how to develop, grow and function. Chromosomes usually come in pairs, with one chromosome from each pair coming from the father and one from the mother.Of the 46 chromosomes, two are a pair of sex chromosomes, XX (two X chromosomes) in females and XY (one X and one Y chromosome) in males. 1p interstitial deletions A chromosome 1p deletion means that the cells of the body have some genetic material missing from one of their 46 chromosomes, in this case from chromosome 1. For healthy development, chromosomes should contain just the right amount of genetic material â not too much and not too little.