(The average rate of speech for English speakers in the United States is about 150 words per minute, by the way.) A speaker's habits also influence how much air pressure is used to produce sound and how s/he uses laryngeal muscles to open and close the vocal folds.
4 Use of methotrexate to treat pregnancy of unknown location.  You may require a second dose of the drug.  You are advised to wait a minimum of 3 months before. trying for a future pregnancy.  You are sometimes more vulnerable to infection (if you. come into contact with someone with flu/common cold. etc).
You should not be on methotrexate if you are pregnant or. thinking about becoming pregnant. This is true for both. men and women. It can cause birth defects. If you have known liver disease or drink alcohol (more than three. drinks per week) you should not be on methotrexate.