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It said that DNA was made up of four bases (adenine, thymine, guanine and cytosine) that were present in regular amounts, but that their organisation was too simple to carry hereditary information. It was Chargaff's work that overturned this.rwin Chargaff. Erwin Chargaff was working at Columbia University in New York in the 1940s when he read Oswald Avery's research about DNA being the hereditary material. From that moment in 1944 he devoted his research to working out the chemical composition of DNA.
Sources of DNA Evidence & DNA Extraction. In terms of forensic DNA analysis, there is a variety of possible sources of DNA evidence. The more useful sources include blood, semen, vaginal fluid, nasal secretions and hair with roots.n the analysis of SNPs, which can consist of up the four alleles, the specific base present in the SNP must be established. This is achieved using DNA sequencing techniques. However DNA sequencing is not generally used in forensic science except in the analysis of mitochondrial DNA.