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DHEA supplementation can increase testosterone levels quite significantly in middle-aged and older men, and in menopausal women. However, these effects are â for some reason â highly unreliable in younger guys.
DHEA may interfere with the way the body processes certain agents using the liver's cytochrome P450 enzyme system. As a result, the levels of these agents may be increased in the blood and may cause increased effects or potentially serious adverse reactions.