Females are usually carriers because they only have one copy of the disease allele. Affected males are related through carrier females. For a carrier female, with each pregnancy there is a one in two (50%) chance her sons will inherit the disease allele and a one in two (50%) chance her daughters will be carriers.
A complimentary close, also known as a complimentary closing, is the term prior to your signature in an email message or formal letter. This sign-off phrase shows your respect and appreciation for the person who is considering the request in your letter or email.
5. Do not use a period to end a sentence which ends with an abbreviation which itself ends with a period. Typical abbreviations which end with a period are: Mr., Mrs., Ms., St. (street or Saint), Mt. (mountain), Dr., Jr., Fri., Feb., a.m. and p.m. (Note: Do not abbreviate professor to Prof. in academic writing).