Females are usually carriers because they only have one copy of the disease allele. Affected males are related through carrier females. For a carrier female, with each pregnancy there is a one in two (50%) chance her sons will inherit the disease allele and a one in two (50%) chance her daughters will be carriers.
A complimentary close, also known as a complimentary closing, is the term prior to your signature in an email message or formal letter. This sign-off phrase shows your respect and appreciation for the person who is considering the request in your letter or email.
The close and signature of the block letter begins at the left margin. The complimentary close begins with a capital letter and ends with a comma. Skip from one to three spaces (two on a typewriter), and type in the signature line, the printed name of the person signing the letter.Sign the name in the space between the close and the signature line, starting at the left edge of the signature line.Women may indicate how they wish to be addressed by placing Miss, Mrs., Ms. or similar title in parentheses before their name. The signature line may include a second line for a title, if appropriate.The signature should start directly above the first letter of the signature line in the space between the close and the signature line. Use blue or black ink.he close and signature of the block letter begins at the left margin. The complimentary close begins with a capital letter and ends with a comma. Skip from one to three spaces (two on a typewriter), and type in the signature line, the printed name of the person signing the letter.