5. Summary & Conclusions CBEA is a key element of enterprise systems engineering; it is the analytical framework that supports capabilities-based planning, programming, and acquisition in a systemic approach to the purposeful evolution of the enterprise.
The genes of telomerase subunits, which include TERT, TERC, DKC1 and TEP1, are located on different chromosomes. The human TERT gene (hTERT) is translated into a protein of 1132 amino acids. TERT polypeptide folds with (and carries) TERC, a non-coding RNA (451 nucleotides long).
Each chromosome is like a DNA library with two protective caps on the end known as telomeres. As telomeres become shorter, their structural integrity weakens, which causes cells to age faster and die younger. In human cells, telomeres are usually single-stranded DNA that contains several thousand repeats of a simple TTAGGG sequence.