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Oral cancer symptoms. Some of the most common oral cancer symptoms and signs include: 1  Persistent mouth sore: A sore in the mouth that does not heal is the most common symptom of oral cancer. 2  Pain: Persistent mouth pain is another common oral cancer sign.  A lump or thickening in the cheek.
Symptoms caused by salivary gland cancer also may be caused by other conditions. 1  A lump (usually painless) in the area of the ear, cheek, jaw, lip, or inside the mouth. 2  Fluid draining from the ear. 3  Trouble swallowing or opening the mouth widely.  Numbness or weakness in the face.