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Look up foramen in Wiktionary, the free dictionary. In anatomy, a foramen (/fÉËreÉªmÉn/; pl. foramina, /fÉËrÃ¦máµ»nÉ/) is any opening. Foramina inside the body of humans and other animals typically allow muscles, nerves, arteries, veins, or other structures to connect one part of the body with another.
Patent foramen ovale (PFO) is an intracardiac defects, or holes in the heart. It is an abnormal openings in the wall (septum) that separates the two atria, or upper chambers, of the heart. PFO results when a normal opening in the septum fails to close after birth.