Learn all about Retrolisthesis, the back pain which is due to the displacement of vertebrae of the spine, its symptoms, causes and treatments used to get rid of it. Retrolisthesis is relatively rare but when present is associated with increased back pain.
One of the best-known chemical mediators released from cells during inflammation is histamine, which triggers vasodilation and increases vascular permeability. Stored in granules of circulating basophils and mast cells, histamine is released immediately when these cells are injured.
The first step of inflammation involves damaged cells of injured tissue, basophils and mast cells to release chemicals (histamines, prostaglandins and chemotactic factors) all stimulate nociceptors which causes pain. Also, the compression of exudate on the endings of nociceptors contributes to the feeling of pain.