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Smallpox was officially declared eradicated in 1980 and is the first disease to have been fought on a global scale.This extraordinary achievement was accomplished through the collaboration of countries around the world. At the end of the 1960s, smallpox was still endemic in Africa and Asia.mallpox was officially declared eradicated in 1980 and is the first disease to have been fought on a global scale.
The cause of smallpox is an infection with the variola virus. This is a double-stranded DNA virus in the family Poxviridae and the genus Orthopoxvirus. Variola virus only infects humans. Thanks to the success of vaccination, the last natural outbreak of smallpox in the United States occurred in 1949. By 1972, routine smallpox vaccinations for children in the United States were no longer needed.