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Fluconazole: Peak plasma concentrations in fasted normal volunteers occur between 1 and 2 hours with a terminal plasma elimination half-life of approximately 30 hours (range: 20 to 50 hours) after oral administration. If you wait 5 half-lives it will all be gone.
Sulfamethoxazole has a half life of 10 hours. Hence sulfamethoxazole does stay in the human body system for around 20 to 24 hours at least. How ever, the traces of sulfamethodazole can be present in the body for a bit longer duration.