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These medical disease topics may be related to ACF: 1  unilateral facial weakness. 2  heart defects. 3  mental retardation. 4  genitourinary abnormalities.
People at this stage will have advanced structural heart disease, and will display significant symptoms of HF even when at rest. This stage is very serious and requires specialist treatmentm, such as mechanical circulatory support, continuous inotropic infusion, cardiac transplant, or hospice care.