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Smallpox was officially declared eradicated in 1980 and is the first disease to have been fought on a global scale.This extraordinary achievement was accomplished through the collaboration of countries around the world. At the end of the 1960s, smallpox was still endemic in Africa and Asia.mallpox was officially declared eradicated in 1980 and is the first disease to have been fought on a global scale.
1 [anno: The smallpox virus normally enters the body through the respiratory system. 2  Smallpox can cause millions of cells within the body to explode. 3  If too many cells explode, entire organs could fail, and a person could die. 4  Smallpox also lives on in the blood after a person has died.mallpox is spread when a person breathes it inâ¦and out. The virus gets inside the cells lining the throat and hijacks the cellular machinery to make millions more smallpox viruses. The cells explode, releasing smallpox âbombs.â Those virus particles go on to infect other cells in the body.