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Smallpox was officially declared eradicated in 1980 and is the first disease to have been fought on a global scale.This extraordinary achievement was accomplished through the collaboration of countries around the world. At the end of the 1960s, smallpox was still endemic in Africa and Asia.mallpox was officially declared eradicated in 1980 and is the first disease to have been fought on a global scale.
During the 20th century, it is estimated that smallpox was responsible for 300â500 million deaths. In the early 1950s an estimated 50 million cases of smallpox occurred in the world each year.As recently as 1967, the World Health Organization estimated that 15 million people contracted the disease and that two million died in that year.he history of smallpox extends into pre-history; the disease likely emerged in human populations about 10,000 BC. The earliest credible evidence of smallpox is found in the Egyptian mummies of people who died some 3000 years ago.