Most doctors no longer recommend niacin for first line cholesterol control â except for people who can't tolerate statins. In those people, the benefits of niacin may outweigh the risk of potentially serious side effects.
The bulge creates a feeling of tightness behind the knee as well as stiffness and swelling and pain behind the knee and calf. For many, this pain intensifies when flexing or fully extending the leg. Often, these cysts go away without any treatment.
The freeMD virtual doctor has found 9 conditions that can cause Leg Pain (below the knee, one leg) and Throbbing Leg Pain. Mouse over to view each condition's most common symptoms. There are 2 common conditions that can cause Leg Pain (below the knee, one leg) and Throbbing Leg Pain. 1  Calf Strain.  Muscle Strains.