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Medical Definition of specialization. 1  1: a making or becoming specialized specialization in pediatrics. 2  2a: structural adaptation of a body part to a particular function or of an organism for life in a particular environmentb: a body part or an organism adapted by specialization.
specialize. 1  to pursue some special line of study, work, etc.; have a specialty: The doctor specializes in gastroenterology. 2  Biology. (of an organism or one of its organs) to be adapted to a special function or environment. 3  to render special or specific; invest with a special character, function, etc.