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As the English, French, and Spanish explorers came to North America, they brought tremendous changes to American Indian tribes. Europeans carried a hidden enemy to the Indians: new diseases.Native peoples of America had no immunity to the diseases that European explorers and colonists brought with them.s the English, French, and Spanish explorers came to North America, they brought tremendous changes to American Indian tribes. Europeans carried a hidden enemy to the Indians: new diseases.
While the French came to American to explore and the Spanish came looking for treasures, the English came for different reasons. 1  Some English came to America to have a chance to practice the religion of their choice. 2  Some religious people came to America to bring their Christian faith to the Native Americans. British judges sent some people to America instead of placing them in British prisons. Businessmen came to America to buy products such as tobacco and furs from the colonists.