Those originally employed were based either on the fusion of the PCE to a tumour specific antibody (Antibody-Directed Prodrug Therapy, ADEPT) or on the delivery of the gene encoding the PCE using viral or non-viral vectors (Gene-Directed Enzyme Prodrug Therapy, GDEPT).
Urea is widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry. Friedrich WÃ¶hler's discovery in 1828 that urea can be produced from inorganic starting materials was an important conceptual milestone in chemistry.
ANYONE TRYING to salvage fertilizer potency may be interested in a newer product. Developed by IMC-Agrico, Agrotain inhibits the break-down of urea into ammonia gas. By slowing the rate of break-down, urea is kept fresh and, thus, more beneficial to plants.he cost for Agrotain is about 2.25 cents per pound of urea. If you're treating 200 pounds of urea, it'll cost about $4 to $5 per acre over the cost of straight urea. âWe've had no problems coating urea with Agrotain. Instinct says that if you put a liquid on urea, it will gum up.