Those originally employed were based either on the fusion of the PCE to a tumour specific antibody (Antibody-Directed Prodrug Therapy, ADEPT) or on the delivery of the gene encoding the PCE using viral or non-viral vectors (Gene-Directed Enzyme Prodrug Therapy, GDEPT).
Urea is widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry. Friedrich WÃ¶hler's discovery in 1828 that urea can be produced from inorganic starting materials was an important conceptual milestone in chemistry.
Below Ground and Other Vegetables. Other vegetables that can tolerate a soil pH of 7.5 include garlic (Allium sativum) and beets (Beta vulgaris). While garlic benefits from being planted the season before, beets can be planted early in the growing season for an early fall harvest.elow Ground and Other Vegetables. Other vegetables that can tolerate a soil pH of 7.5 include garlic (Allium sativum) and beets (Beta vulgaris). While garlic benefits from being planted the season before, beets can be planted early in the growing season for an early fall harvest.