Most doctors no longer recommend niacin for first line cholesterol control â except for people who can't tolerate statins. In those people, the benefits of niacin may outweigh the risk of potentially serious side effects.
The bulge creates a feeling of tightness behind the knee as well as stiffness and swelling and pain behind the knee and calf. For many, this pain intensifies when flexing or fully extending the leg. Often, these cysts go away without any treatment.
What can pain behind the knee be a symptom of? Swelling from knee injuries and ailments produces lump-like appearances on both sides of the knee. For example, the bursa, a sac of fluid that protects and cushions the joints, can become irritated and enlarged, explains WebMD.