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Fluconazole: Peak plasma concentrations in fasted normal volunteers occur between 1 and 2 hours with a terminal plasma elimination half-life of approximately 30 hours (range: 20 to 50 hours) after oral administration. If you wait 5 half-lives it will all be gone.
The drug flagyl or metronidazole stays in the system 3 days after discontinuation.Dont drink alcohol till 3 days after you stop it [ Source: http://www.chacha.com/question/how-long-does-flagyl-stay-in-your-body ]. More Answers to  How long does flagyl stay in your body .his means that every 8 hours, the amount in the body is cut in half. We usually give 4-5 half-lives to say that the drug is gone (it will be about 95% gone by then), so 32-40 hours for metronidazole (Flagyl).