Abstract. 1  Sperm and egg production requires a robust stem cell system that balances self-renewal with differentiation. Self-renewal at the expense of differentiation can cause tumorigenesis, whereas differentiation at the expense of self-renewal can cause germ cell depletion and infertility. In most organisms, and sometimes in both sexes, germline stem cells (GSCs) often reside in a defined anatomical niche. Factors within the niche regulate a balance between GSC self-renewal and differentiation. Asymmetric division of the germline stem cell to form daughter cells with alternative fates is common.
Heartgard Plus is a real-beef chewable tablet for dogs that provides protection against heartworms, and treats and controls roundworms and hookworms. Heartgard Plus is given monthly and requires a prescription from your veterinarian.
Step Two: Treating the Disease. Once your dog has completed the course of steroids, heartworm preventive and antibiotics, he should be ready to start the actual adult heartworm treatment. The treatment for heartworm disease takes at least 60 days to complete and consists of a series of drug injections that kills the worms. There is only one drug approved by the Food and Drug Administration to kill adult heartworms in dogs, an organic arsenical compound that is injected into the dog's lumbar, or back, muscles.