Common causes of skin changes include: 1  Skin puckering or dimpling. 2  Skin puckering or dimpling can be caused by scarring from a previous operation or infection, but in the majority of cases, no specific reason can be found. 3  Most often it is not a sign of underlying cancer, but should be evaluated with exam and imaging.
By Mayo Clinic Staff. Night leg cramps, also called nocturnal leg cramps, are painful, involuntary contractions or spasms of muscles in your legs, usually occurring when you're in bed. Night leg cramps usually involve your calf muscles, although muscles in your feet or thighs might cramp as well.
b> Muscle cramps develop when a muscle involuntarily tightens and will not relax, causing sharp, intense pain. ... The main cause of leg cramps is muscle overuse. Other, less common causes of leg cramps include: Dehydration; Muscle strain or injury; Lack of the minerals potassium ... What causes leg cramps at night www.lifescript.com/health/briefs/w/what_causes_leg_cramps_at_night.aspx.