Comment. If we are to believe this study, then there is indeed a dose-dependent correlation between alcohol abuse and paradoxical excitement response in patients sedated with propofol. The authors (and other before them) suggest this has to to with genetic variations of the GABA-receptors.
Medical Attention for a Painkiller Overdose. A known or suspected painkiller overdose is a medical emergency that requires immediate assistance. Contact your local emergency number or 9-1-1 to get help. Tell the paramedics how much of the drug was ingested and the time in which it was ingested.
What happens if I miss a dose (Estratab, Menest)? Take the missed dose as soon as you remember. Do not take a double dose of this medication unless otherwise directed by your doctor. What happens if I overdose (Estratab, Menest)? An overdose of this medication is unlikely to threaten life. Consult an emergency room or poison control center for advice.