Downstream of dams, marked changes in fish populations occur as a consequence of blockage of migration routes, disconnection of the river and floodplain and changes in flow regime, physiochemical conditions (e.g. temperature, turbidity and dissolved oxygen), primary production and channel morphology.
A final consideration is allergic reactions to the glaucoma drugs. âWith both Combigan and Simbrinza, the allergy rates are unknown. Brimonidine is a component of both drugs; when it was first introduced, it was associated with a 20% allergy rate.he availability of combination anti-glaucoma therapies is a boon for patients and physicians when considering that about 40% of patients with glaucoma require two or more drugs to control elevated IOP levels.
These glaucoma drugs also reduce the production of aqueous humor. Examples of such glaucoma drugs include Dorzolamide (Brand name: Trusopt) and Brinzolamide (Brand name: Azopt). Some of the side-effects of these glaucoma drugs include frequent urination and a tingling sensation in the fingers and toes.