Those originally employed were based either on the fusion of the PCE to a tumour specific antibody (Antibody-Directed Prodrug Therapy, ADEPT) or on the delivery of the gene encoding the PCE using viral or non-viral vectors (Gene-Directed Enzyme Prodrug Therapy, GDEPT).
Urea is widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry. Friedrich WÃ¶hler's discovery in 1828 that urea can be produced from inorganic starting materials was an important conceptual milestone in chemistry.
Approved for organic gardening. Bonide Liquid Copper Fungicide controls a large variety of plant diseases, including peach leaf curl, powdery mildew, black spot, rust, anthracnose, fire blight and bacterial leaf spot.Use on vegetables, roses, fruits and turf. Can be used up to the day of harvest.Available size: Pint (16oz).ix 0.5 to 2.0 oz. Liquid Copper per gallon of water. For best results, start spraying before the disease is visible or when it is first noticed on the plant. Spray all plant parts thoroughly, and repeat every 7-10 days. If possible, time applications so that at least 12 hours of dry weather follows application.