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Many side effects of iron supplements, including nausea, leg cramps, diarrhea and constipation, tend to go away as the patient's body adapts to the supplement, explains Mayo Clinic. Patients who are extremely bothered by these side effects can contact their doctors for advice to reduce the symptoms but should not be alarmed.
In some people, iron supplements can cause stomach discomfort, nausea, diarrhea, constipation, and black stool. Iron is best absorbed if taken on an empty stomach. But if you are having stomach problems, you may need to take the pills with food. If the side effects of your iron pills make you feel too sick, talk to your doctor. He or she may know of another type of iron pill you can take. If you think you have anemia, do not take iron pills without talking with your doctor.