Those originally employed were based either on the fusion of the PCE to a tumour specific antibody (Antibody-Directed Prodrug Therapy, ADEPT) or on the delivery of the gene encoding the PCE using viral or non-viral vectors (Gene-Directed Enzyme Prodrug Therapy, GDEPT).
Urea is widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry. Friedrich WÃ¶hler's discovery in 1828 that urea can be produced from inorganic starting materials was an important conceptual milestone in chemistry.
Use Produce Power A diet rich in fruits, whole grains and vegetables appears to lower the risk of many cancers, including colon cancer. Vegetables most likely to help prevent colon cancer are broccoli, cabbage, cauliflower, kale and other members of the cruciferous family. A diet rich in produce may be beneficial, in part, because these foods tend to be high in folate, a B vitamin.