A digoxin test may be ordered when it is suspected that levels are too low in someone who is taking the medication and has symptoms of heart failure such as: 1  Fatigue. 2  Shortness of breath. 3  Swelling in the hands and feet (edema).
lupus is a systemic autoimmune disease that has some genetic factors it is also tied to environmental risk which may determine whether people actually ever manifest the illnessthese environmental factors may also play a role in the degree to which lupus may affect a person s life and mortalityupus can manifest in different parts of the body but may include joint pain swollen legs and feet may be symptoms of lupus nephritis a form of renal parenchymal disease people can have a genetic predisposition for lupus
The genetic basis of Down syndrome. Down syndrome is a genetic disorder caused when abnormal cell division results in extra genetic material from chromosome 21. This genetic disorder, which varies in severity, causes lifelong intellectual disability and developmental delays, and in some people it causes health problems. Down syndrome is the most common genetic chromosomal disorder and cause of learning disabilities in children. Better understanding of Down syndrome and early interventions can greatly increase the quality of life for children and adults with this disorder and help them live fulfilling lives.