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PTT is âpartial thromboplastin timeâ, and PT is âprothrombin time.â Both PTT and PT are tests used for measuring the time taken for the blood to clot. These two tests are mainly conducted for checking for bleeding problems or the chances of excessive bleeding during surgery.
The tests for thiopurine methyltransferase (TPMT) enzyme activity or its underlying genetics are measured in people who are about to start treatment with a thiopurine drug. One or the other of these tests is used to identify individuals at risk of developing severe side effects from thiopurine therapy.