An advance is usually 1/3 of the first print run total royalties. For example, if a book has a print run of 5000 copies and will be sold at $14.95 and the author is to receive 10% royalties, the total sum payable to the author if all copies are sold is $7475 (10% x $14.95 x 5000).
Mayo Clinic researchers have found that a sometimes deadly stomach bug, Clostridium difficile, is on the rise in outpatient settings. Clostridium difficile is a serious bacteria that can cause symptoms ranging from diarrhea to life-threatening inflammation of the colon.
The brown recluse spider is one of the most dangerous spiders in the United States. Its venom destroys the walls of blood vessels near the site of the bite, sometimes causing a large skin ulcer. Research in 2013 revealed that a protein in the spiderâs venom targets phospholipid molecules, which make up a good portion of cell membranes, and transforms these molecules into simpler lipids.