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Knee pain and related symptoms may derive from damage to one or more of the soft tissue structures that stabilize and cushion the knee joint (including the ligaments, muscles, tendons, and menisci), from infection to the knee joint or surrounding structures, or from trauma to the bones forming the joint.
IT (iliotibial) band syndrome: The iliotibial (IT) band is a piece of tough tissue that runs from your hip down to the outer part of your knee. When you overdo activity, it can become inflamed over time. That causes pain on the outer side of the knee and is common in runners when going downhill. Loose cartilage: Sometimes, a knee injury can break loose cartilage. These pieces can get stuck in the joint, which causes pain and swelling.