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Oral cancer symptoms. Some of the most common oral cancer symptoms and signs include: 1  Persistent mouth sore: A sore in the mouth that does not heal is the most common symptom of oral cancer. 2  Pain: Persistent mouth pain is another common oral cancer sign.  A lump or thickening in the cheek.
Symptoms of this cancer may depend on where the cancer develops and how it spreads. For example, tumors in the larynx or pharynx may be discovered as a lump in the throat. Cancer in the mouth may cause sores in the mouth or swelling of the jaw. In addition to physical signs of head and neck cancer, these diseases often cause symptoms that are similar to less serious conditions, like the common cold. Changes in voice, headaches, sore throat or a cough may be symptoms of throat cancer.