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PVR occurs in about 8â10% of patients undergoing primary retinal detachment surgery and prevents the successful surgical repair of rhegmatogenous retinal detachment. PVR can be treated with surgery to reattach the detached retina but the visual outcome of the surgery is very poor.PVR was originally referred to as massive vitreous retraction and then as massive periretinal proliferation. The name Proliferative vitreo retinopathy was provided in 1989 by the Silicone Oil Study group. number of cytokines such as tumor necrosis factor alpha (TNFÎ±), transforming growth factor beta 2 (TGFÎ² 2), platelet derived growth factor (PDGF) and interleukins have been shown to play a role in PVR progression.
A vitrectomy is an operation to remove the vitreous gel from the inside of the eye. This is necessary in order to carry out procedures that cannot be performed with the fluid in its place. The vitreous is a clear jelly-like substance which occupies about two-thirds of the eye, lying between the lens and the retina.erious injury to the eye may also result in a vitreous haemorrhage. Primary retinal detachment repair: to learn about why a vitrectomy is required for a retinal detachment click here (link). Diabetic retinopathy: to learn about why a vitrectomy is required for diabetic retinopathy click here (link).