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The identification of mature and immature blood cells in peripheral blood smears and bone marrow preparations is fundamental to the laboratory diagnosis of haematological disorders. Here, you may review the mature and immature white cells to gain more practice and confidence in their identification.
Comprehensive diagram that shows the development of different blood cells from haematopoietic stem cell to mature cells. Haematopoietic stem cells (HSCs) reside in the medulla of the bone (bone marrow) and have the unique ability to give rise to all of the different mature blood cell types and tissues. HSCs are self-renewing cells: when they proliferate, at least some of their daughter cells remain as HSCs, so the pool of stem cells is not depleted.This phenomenon is called asymmetric division.