Abstract. 1  Sperm and egg production requires a robust stem cell system that balances self-renewal with differentiation. Self-renewal at the expense of differentiation can cause tumorigenesis, whereas differentiation at the expense of self-renewal can cause germ cell depletion and infertility. In most organisms, and sometimes in both sexes, germline stem cells (GSCs) often reside in a defined anatomical niche. Factors within the niche regulate a balance between GSC self-renewal and differentiation. Asymmetric division of the germline stem cell to form daughter cells with alternative fates is common.
Nuheart Heartworm medicine plays an important role in dog heartworm and canine heartworm. Nuheart Heartworm prevention and heartworm treatment comprises of heartworm pill or heartworm tablets. Nuheart Generic heartgard was used by heartworm meds previously.
Certain forms of heartworm prevention may be harmful to dogs that are heartworm positive. Giving your dog heartworm prevention is an ESSENTIAL part of being a responsible dog owner. In addition, it is safer and less expensive to prevent heartworms than to put your dog through heartworm treatment for heartworm disease. Heartworm prevention costs about $35-$250 per year depending on the size of the dog and the brand of prevention chosen.