Abstract. 1  Sperm and egg production requires a robust stem cell system that balances self-renewal with differentiation. Self-renewal at the expense of differentiation can cause tumorigenesis, whereas differentiation at the expense of self-renewal can cause germ cell depletion and infertility. In most organisms, and sometimes in both sexes, germline stem cells (GSCs) often reside in a defined anatomical niche. Factors within the niche regulate a balance between GSC self-renewal and differentiation. Asymmetric division of the germline stem cell to form daughter cells with alternative fates is common.
RSPCA Heartworm Tablet is a monthly heartworm preventive for dogs. The oral treatment prevents heartworm disease in dogs by eliminating the tissue stage of heartworm that infects the dog one month before by mosquitoes. Monthly treatment all year round protects dog from deadly heartworm infection. RSPCA heartworm tablet is easy to dose and highly economical. With no possible side effects, it is approved for adult dogs. RSPCA Heartworm tablets is safe for puppies above 6 weeks old.
There are many different types of heartworm medication, ranging from chewable tablets to spot on treatments. Learn about the different options here. READ more; 5 Facts on Heartworm Disease in Dogs. Heartworm infections can and will turn into heartworm disease if left untreated and can be potentially fatal to your dog.