Learn all about Retrolisthesis, the back pain which is due to the displacement of vertebrae of the spine, its symptoms, causes and treatments used to get rid of it. Retrolisthesis is relatively rare but when present is associated with increased back pain.
One of the best-known chemical mediators released from cells during inflammation is histamine, which triggers vasodilation and increases vascular permeability. Stored in granules of circulating basophils and mast cells, histamine is released immediately when these cells are injured.
Histamine is present abundantly in the granules of tissue mast cells and circulating basophils. One of the stimuli that activate mast cells and basophils to release histamine is the binding of antigens to cell-bound IgE antibodies on the surfaces of mast cells and basophils.nother stimulus that activates mast cells to release histamine is the binding of C3a and C5a fragments of complement to specific receptors on mast cells. Activated mast cells release massive amounts of histamine into the surrounding tissue.