Abstract. 1  Sperm and egg production requires a robust stem cell system that balances self-renewal with differentiation. Self-renewal at the expense of differentiation can cause tumorigenesis, whereas differentiation at the expense of self-renewal can cause germ cell depletion and infertility. In most organisms, and sometimes in both sexes, germline stem cells (GSCs) often reside in a defined anatomical niche. Factors within the niche regulate a balance between GSC self-renewal and differentiation. Asymmetric division of the germline stem cell to form daughter cells with alternative fates is common.
Nuheart Heartworm medicine plays an important role in dog heartworm and canine heartworm. Nuheart Heartworm prevention and heartworm treatment comprises of heartworm pill or heartworm tablets. Nuheart Generic heartgard was used by heartworm meds previously.
Heartworms are spread to dogs through mosquito bites. Up to 14 inches long, a heartworm lives in the heart and the arteries that carry blood from the heart to the lungs. Heartworms affect how the heart functions and how blood clots and is likely to cause death if untreated. Monthly heartworm preventives are effective.