Derby shoe. A derby (pronounced /ËdÉËrbi/ DAR-bee or in North American English /ËdÉËrbi/ DUR-bee; also called gibson) is a style of boot or shoe characterized by quarters with shoelace eyelets that are sewn on top of the vamp. This construction method, also known as open lacing, contrasts with that of the oxfords.
Dengue is an infectious disease caused by dengue viruses, which are transmitted to humans by mosquitoes. The rising level of dengue infections has become a serious international concern.
Each year, the virus infects up to 100 million people and kills about 22,000, most of them children. To infect a cell, the dengue virus initially binds to the cell surface. It gains entry into the cell when it becomes enveloped by the cell membrane during the creation of a pouch-like structure known as an endosome.