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Oral cancer symptoms. Some of the most common oral cancer symptoms and signs include: 1  Persistent mouth sore: A sore in the mouth that does not heal is the most common symptom of oral cancer. 2  Pain: Persistent mouth pain is another common oral cancer sign.  A lump or thickening in the cheek.
Lymphoma: Enlarged, rubbery lymph nodes, itchy skin, night sweats, unexplained, fever and weight loss can be signs of Lymphoma. Mouth and Throat Cancer: Any chronic ulcer (sore) of the mouth, tongue or throat which doesn't heal, or white areas in the mouth should be seen by your physician.