Abstract. 1  Sperm and egg production requires a robust stem cell system that balances self-renewal with differentiation. Self-renewal at the expense of differentiation can cause tumorigenesis, whereas differentiation at the expense of self-renewal can cause germ cell depletion and infertility. In most organisms, and sometimes in both sexes, germline stem cells (GSCs) often reside in a defined anatomical niche. Factors within the niche regulate a balance between GSC self-renewal and differentiation. Asymmetric division of the germline stem cell to form daughter cells with alternative fates is common.
Heartgard Plus is a real-beef chewable tablet for dogs that provides protection against heartworms, and treats and controls roundworms and hookworms. Heartgard Plus is given monthly and requires a prescription from your veterinarian.
MYTH 3: Treatment for heartworm disease is just as easy as preventing it. FACT: Treatment requires arsenic-based injections to kill the heartworms living in a dogâs lungs and heart. In comparison to heartworm prevention, the treatment is expensive (up to $1,000) and can be traumatic and risky. It is much easier to prevent heartworms than to treat them.