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Fluconazole: Peak plasma concentrations in fasted normal volunteers occur between 1 and 2 hours with a terminal plasma elimination half-life of approximately 30 hours (range: 20 to 50 hours) after oral administration. If you wait 5 half-lives it will all be gone.
2 How long for metronidazole and clarithromycin to get out of your system? 40 and 15-20 hours: The half life of Metronidazole is 8 hours. The half life of Clarithromycin is 3-4 hours. Half life is the time for the body to eliminate and excrete 1/2 of the drug. It is felt that a drug is completely eliminated after 5 half lives. So 40 hours for Metronidazole and 15-20 hours for clarithromycin.