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Knee pain and related symptoms may derive from damage to one or more of the soft tissue structures that stabilize and cushion the knee joint (including the ligaments, muscles, tendons, and menisci), from infection to the knee joint or surrounding structures, or from trauma to the bones forming the joint.
1 Inside of Knee: Pain on the inside, or medial side, of the knee, is commonly caused by medial meniscus tears, MCL injuries, and arthritis.  Outside of Knee: Pain on the outside of the knee, or lateral side, is commonly caused by lateral meniscus tears, LCL injuries, IT band tendonitis, and arthritis.