An advance is usually 1/3 of the first print run total royalties. For example, if a book has a print run of 5000 copies and will be sold at $14.95 and the author is to receive 10% royalties, the total sum payable to the author if all copies are sold is $7475 (10% x $14.95 x 5000).
Mayo Clinic researchers have found that a sometimes deadly stomach bug, Clostridium difficile, is on the rise in outpatient settings. Clostridium difficile is a serious bacteria that can cause symptoms ranging from diarrhea to life-threatening inflammation of the colon.
Although bed bug bites themselves aren't harmful to humans, affects of bed bug bites can cause health complications like sleep deprivation and anemia from loss of blood. Although the bites are intrinsically dangerous, the bites are itchy, and often require over-the-counter treatment to relieve the itchiness. Below is an article from Bed Bugs and Beyond detailing the deleterious affects bed bugs can have on your health, and how to relieve the discomfort caused by bed bugs.