To make sure estradiol is safe for you, tell your doctor if you have: 1  heart disease; 2  risk factors for coronary artery disease (such as diabetes, lupus, smoking, being overweight, having high blood pressure or high cholesterol, having a family history of coronary artery disease, or if you have had a hysterectomy);
(a form of the possessive case of you used as an attributive adjective): Your jacket is in that closet. I like your idea. Compare yours. 2. one's (used to indicate that one belonging to oneself or to any person): The consulate is your best source of information. As you go down the hill, the library is on your left.
Pronouns are generic words that have little meaning on their own. If you hear a friend say, She is beautiful, you know your friend is referring to a singular, feminine being or object, but with just the pronoun she, you don't know if the discussion concerns a woman, a cheetah, or an automobile.