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Smallpox was officially declared eradicated in 1980 and is the first disease to have been fought on a global scale.This extraordinary achievement was accomplished through the collaboration of countries around the world. At the end of the 1960s, smallpox was still endemic in Africa and Asia.mallpox was officially declared eradicated in 1980 and is the first disease to have been fought on a global scale.
And that may yank us back to where we were in the 1940s.â. 1  Smallpox â âWashington was infected by smallpox at about age 19. 2  This is a serious, serious disease, where you get blistery lesions all over the face. 3  Its effects on the internal organs are what kill 1 out of 3 victims.