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Many side effects of iron supplements, including nausea, leg cramps, diarrhea and constipation, tend to go away as the patient's body adapts to the supplement, explains Mayo Clinic. Patients who are extremely bothered by these side effects can contact their doctors for advice to reduce the symptoms but should not be alarmed.
You can reduce side effects from iron pills by taking these steps: 1  Start with half of the recommended dose. Gradually increase to the full dose. 2  Take iron in divided doses. For example, if you take two pills daily, take one in the morning with breakfast and the other after dinner. Take iron with food (especially something with vitamin C, such as a glass of orange juice, to help your body absorb the iron). If one type of iron pill causes side effects, ask your doctor for another type. If you take iron as a liquid instead of as a pill, aim it toward the back of your mouth. This will prevent the liquid from staining your teeth.