Comment. If we are to believe this study, then there is indeed a dose-dependent correlation between alcohol abuse and paradoxical excitement response in patients sedated with propofol. The authors (and other before them) suggest this has to to with genetic variations of the GABA-receptors.
Medical Attention for a Painkiller Overdose. A known or suspected painkiller overdose is a medical emergency that requires immediate assistance. Contact your local emergency number or 9-1-1 to get help. Tell the paramedics how much of the drug was ingested and the time in which it was ingested.
But something goes wrong, and now your friend is overdosing. He needs helpâquickâor he might die. If you call 911, you might save his life: Many first responders carry a quick-acting drug called naloxone that can reverse the effects of an opioid overdose. But calling 911 puts you at risk of being arrested for drug possession. What do you do?