An advance is usually 1/3 of the first print run total royalties. For example, if a book has a print run of 5000 copies and will be sold at $14.95 and the author is to receive 10% royalties, the total sum payable to the author if all copies are sold is $7475 (10% x $14.95 x 5000).
Mayo Clinic researchers have found that a sometimes deadly stomach bug, Clostridium difficile, is on the rise in outpatient settings. Clostridium difficile is a serious bacteria that can cause symptoms ranging from diarrhea to life-threatening inflammation of the colon.
Examples of problems that are more serious include: 1  A severe allergic reaction (anaphylaxis). Severe allergic reactions are not common but can be life-threatening and require emergency care. 2  A toxic reaction to a single sting or bite. Spiders or insects that may cause this include: Black widow spider. Brown recluse spider. Scorpion. Puss caterpillar (woolly slug). A toxic reaction to multiple stings or bites from a bee, wasp, or fire ant. A bee leaves its stinger behind and then dies after stinging.