An advance is usually 1/3 of the first print run total royalties. For example, if a book has a print run of 5000 copies and will be sold at $14.95 and the author is to receive 10% royalties, the total sum payable to the author if all copies are sold is $7475 (10% x $14.95 x 5000).
Mayo Clinic researchers have found that a sometimes deadly stomach bug, Clostridium difficile, is on the rise in outpatient settings. Clostridium difficile is a serious bacteria that can cause symptoms ranging from diarrhea to life-threatening inflammation of the colon.
A bite from a poisonous spider like the black widow or brown recluse is extremely dangerous and can cause a severe reaction. The black widow's bite, which shows up as two puncture marks, may or may not be painful at first. But 30 to 40 minutes later, you may have pain and swelling in the area.