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PTT is âpartial thromboplastin timeâ, and PT is âprothrombin time.â Both PTT and PT are tests used for measuring the time taken for the blood to clot. These two tests are mainly conducted for checking for bleeding problems or the chances of excessive bleeding during surgery.
When an initial PTT is prolonged, a second PTT test is performed by mixing the person's plasma with pooled normal plasma (a collection of plasma from a number of normal donors). If the PTT time returns to normal (corrects), it suggests a deficiency of one or more of the coagulation factors in the person's plasma. If the time remains prolonged, then the problem may be due to the presence of an abnormal specific factor inhibitor (autoantibody) or nonspecific lupus anticoagulant.