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Sarsaparilla and root beer are made from the roots of native North American plants. Both originated as tonics and were highly prized for their medicinal value. Sarsaparilla is made from the sarsaparilla vine, while root beer was originally made from the roots of the sassafras tree. Modern root beers do not contain sassafras because of potential health risks of the plant.
Cascara sagrada is a natural laxative made from the reddish-brown bark of a tree (Rhamnus purshiana) native to the Pacific Northwest. It was used by various Native American tribes, who also passed their âsacred barkâ on to Spanish explorers (cascara sagrada means sacred bark in Spanish).ong-term use of any laxative, including cascara sagrada, can lead to a potassium deficiency. A low potassium level in the body can potentiate (increase) the effect of digitalis drugs and cause dangerous heart beat irregularities.