Those originally employed were based either on the fusion of the PCE to a tumour specific antibody (Antibody-Directed Prodrug Therapy, ADEPT) or on the delivery of the gene encoding the PCE using viral or non-viral vectors (Gene-Directed Enzyme Prodrug Therapy, GDEPT).
Urea is widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry. Friedrich WÃ¶hler's discovery in 1828 that urea can be produced from inorganic starting materials was an important conceptual milestone in chemistry.
Commonly Known Cruciferous Vegetables. Broccoli and cauliflower are commonly known vegetables that are considered cruciferous vegetables. It is important to note that high heat can decrease the beneficial effects of these vegetables.Instead of boiling, lightly steam, saute or stir-fry these vegetables.ommonly Known Cruciferous Vegetables. Broccoli and cauliflower are commonly known vegetables that are considered cruciferous vegetables. It is important to note that high heat can decrease the beneficial effects of these vegetables.