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Proliferative vitreoretinopathy (PVR) is a disease that develops as a complication of rhegmatogenous retinal detachment. number of cytokines such as tumor necrosis factor alpha (TNFÎ±), transforming growth factor beta 2 (TGFÎ² 2), platelet derived growth factor (PDGF) and interleukins have been shown to play a role in PVR progression.
Definition of Proliferative. Proliferative: Growing and increasing in number rapidly. For example, the lymphoproliferative disorders are diseases in which there is malignant growth of lymphoid cells and of cells from the reticuloendothelial system (which take up and sequester inert particles).