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Nerve disorders can affect the entire body or just one area of the body. A number of different causes can contribute to nerve disorder in dogs, and the most common causes include: injury, eating or drinking toxins or poisons, obesity, side effects from medications, certain types of diseases, and inherited disorders.
1 Hypothyroidism is the most common endocrine disease in dogs. 2  It can be caused by autoimmune destruction (lymphocytic thyroiditis) or idiopathic atrophy of the thyroid gland. 3  These two causes are responsible for over 95% of the hypothyroidism cases in dogs. Liver failure * is common in dogs. 2  Signs include vomiting, loss of appetite, weight loss, and jaundice. 3  Causes include bacterial or viral infection, toxic insult, cancer, copper storage diseases, or it may be idiopathic.