Abstract. 1  Sperm and egg production requires a robust stem cell system that balances self-renewal with differentiation. Self-renewal at the expense of differentiation can cause tumorigenesis, whereas differentiation at the expense of self-renewal can cause germ cell depletion and infertility. In most organisms, and sometimes in both sexes, germline stem cells (GSCs) often reside in a defined anatomical niche. Factors within the niche regulate a balance between GSC self-renewal and differentiation. Asymmetric division of the germline stem cell to form daughter cells with alternative fates is common.
Heartgard Plus is a real-beef chewable tablet for dogs that provides protection against heartworms, and treats and controls roundworms and hookworms. Heartgard Plus is given monthly and requires a prescription from your veterinarian.
Specific treatment of lungworm: For treatment of lungworm in dogs administer 50mg fenbendazole (half the normal dose) per day for 7 consecutive days. For treatment of lungworm in cats administer 50mg fenbendazole (half the normal dose) per day for 3 consecutive days. See below for the correct dosage for your animal. 1  1g Sachet- treats 4kg of bodyweight.  1.8g Sachet- treats 8kg of bodyweight.