Paget disease of the breast is named after the 19th century British doctor Sir James Paget, who, in 1874, noted a relationship between changes in the nipple and breast cancer. (Several other diseases are named after Sir James Paget, including Paget disease of bone and extramammary Paget disease, which includes Paget disease of the vulva and Paget disease of the penis.
The 2015 Major League Soccer season features 20 total clubs (17 based in the United States, 3 based in Canada). The regular season is held from March 6 through to October 25, whereas the MLS Cup Playoffs will be held from October 28 to early December. The defending MLS Cup champions are the LA Galaxy, while Seattle Sounders FC are the defending Supporters' Shield winners.
Not sure if the question has been edited (previous answers are for the 2015 season), but the 2016 League Year begins on March 15, 2016, at 4 pm, which marks the start of free agency. The first game of the regular season will be Thursday, Sept. 8th, 2016. Crysti Drake, Am a University of Oklahoma grad.