Car tuning - Areas of modification. 1  The essence of modification of a tuner car is an attempt to extract the greatest possible performanceâor the appearance of high performanceâfrom the base motor vehicle through the addition, alteration or outright replacement of parts.
The distribution of weakness is typically proximal, with variable involvement of [â¦] Nemaline myopathy (NM) is a disorder characterized by muscle weakness, depressed/absent deep tendon reflexes and the presence of rod-shaped structures in muscle cells.
Congenital myopathy. Congenital myopathy is a very broad term for any muscle disorder present at birth. This defect primarily affects skeletal muscle fibres and causes muscular weakness and/or hypotonia. Congenital myopathies account for one of the top neuromuscular disorders in the world today, comprising approximately 6 in 100,000 live births every year. As a whole, congenital myopathies can be broadly classified as follows: A distinctive abnormality in skeletal muscle fibres on the cellular level; observable via light microscope; Symptoms of muscle weakness and hypotonia; Is a congenital disorder, meaning it occurs during development and symptoms present themselves at birth or in early life.