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Fluconazole: Peak plasma concentrations in fasted normal volunteers occur between 1 and 2 hours with a terminal plasma elimination half-life of approximately 30 hours (range: 20 to 50 hours) after oral administration. If you wait 5 half-lives it will all be gone.
DRUG CLASS AND MECHANISM: Fluconazole is an anti-fungal medication related to clotrimazole (Lotrimin), ketoconazole (Nizoral), itraconazole (Sporanox), and miconazole (Micatin, Monistat). It prevents growth of fungi by preventing production of the membranes that surround fungal cells. The FDA approved fluconazole in January 1990. PRESCRIBED FOR: Fluconazole is used for treating vaginal, oral, and esophageal fungal infections caused by Candida. It may also be effective in treating urinary tract infections, peritonitis, pneumonia and disseminated infections caused by Candida. Fluconazole is used for treating cryptococcal meningitis, and prevention of Candida infections in patients treated with chemotherapy or radiation after bone marrow transplantation.