The immune system can distinguish between normal, healthy cells and unhealthy cells by recognizing a variety of danger cues called danger-associated molecular patterns (DAMPs). Cells may be unhealthy because of infection or because of cellular damage caused by non-infectious agents like sunburn or cancer.he immune system can distinguish between normal, healthy cells and unhealthy cells by recognizing a variety of danger cues called danger-associated molecular patterns (DAMPs). Cells may be unhealthy because of infection or because of cellular damage caused by non-infectious agents like sunburn or cancer.
Time-weighted return. The time-weighted return (TWR) (or true time-weighted rate of return (TWRR)) is a method of calculating investment return. To apply the time-weighted return method, combine the return over sub-periods, by compounding them together, resulting in the overall period return. The rate of return over each different sub-period is weighted according to the duration of the sub-period.
Pillar One: Speed. For fast and easy returns management, automate decisions about whether to generate return material authorizations (RMAs) and how to process returned material. Three tools to speed returns processing are: Automated workflows. The disposition of the return depends on data points scattered throughout the enterprise: the item's value and materials, repair scope and cost, return source, and customer service contracts.