DRUG CLASS AND MECHANSIM: Colchicine is an oral drug used for treating acute gout and familial Mediterranean fever (FMF). In acute gout there is severe inflammation in response to the presence of uric acid crystals that form in bony joints.This causes severe pain, redness, and swelling of the affected joint(s).RESCRIBED FOR: Colchicine is used for the treatment of acute flares of gout. It also is used for treating FMF in adults and children 4 years of age or older.
Systemic mean arterial pressure (MAP) is defined as the mean perfusion pressure throughout the cardiac cycle. MAP is sensed by baroreceptors located in the carotid sinuses and the arch of the aorta. These receptors control arterial pressure mainly by adjusting heart rate and arteriolar vessel radius.
The pressure that should be recorded is the pressure found during the first return of a pulse to the cuffed limb. The blood pressure in each leg is divided by the blood pressure in the higher pressure of the two arms to obtain an ABI for each lower extremity. An ABI above 0.9 is normal, except when it exceeds 1.3 (an indicator of severe peripheral arterial obstruction).