The immune system can distinguish between normal, healthy cells and unhealthy cells by recognizing a variety of danger cues called danger-associated molecular patterns (DAMPs). Cells may be unhealthy because of infection or because of cellular damage caused by non-infectious agents like sunburn or cancer.he immune system can distinguish between normal, healthy cells and unhealthy cells by recognizing a variety of danger cues called danger-associated molecular patterns (DAMPs). Cells may be unhealthy because of infection or because of cellular damage caused by non-infectious agents like sunburn or cancer.
Time-weighted return. The time-weighted return (TWR) (or true time-weighted rate of return (TWRR)) is a method of calculating investment return. To apply the time-weighted return method, combine the return over sub-periods, by compounding them together, resulting in the overall period return. The rate of return over each different sub-period is weighted according to the duration of the sub-period.
Background. I am trying to figure out the computational difference between Time-Weighted Rate of Return (TWRR) and Money-Weighted Rate of Return (MWRR). Let's say, I have a portfolio looking like this: 1  2012-Q4 - Begin Market Value (BMV) is $10,000, and End Market Value (EMV) $11,000.odified Dietz return :- http://en.wikipedia.org/wiki/Modified_Dietz_method. Backcalculating the final value (v3) using the calculated returns show the advantage of the money-weighted return over the true time-weighted return.