Adenocarcinoma of the esophagus, the cancer that is especially associated with Barrett's esophagus, is currently the most rapidly rising cancer in the U.S., with a sixfold increase in cases during the past 30 years, according to the National Cancer Institute.
For other uses, see Nero Wolfe (disambiguation). Nero Wolfe is a fictional character, a brilliant, oversize, eccentric armchair detective created in 1934 by American mystery writer Rex Stout. Wolfe was born in Montenegro and keeps his past murky.
Although it was closely related to the gray wolf and other sister species, C. dirus is not the direct ancestor of any modern species. Unlike the gray wolf, which is of Eurasian origin, the dire wolf evolved on the North American continent, along with the coyote.alamander Cave in the Black Hills of South Dakota has produced the oldest known fossil of what is thought to be a dire wolf. The site preserves a fauna approximately 252,000 years old, based on uranium-series dating of a horse fossil found there.