Definition of TISSUE PLASMINOGEN ACTIVATOR. : a clot-dissolving enzyme with an affinity for fibrin that is produced naturally in blood vessel linings and is used in a genetically engineered form to prevent damage to heart muscle following a heart attack and reduce neurological damage following ischemic stroke âabbreviation TPA.ADVERTISEMENT. a clot-dissolving enzyme with an affinity for fibrin that is produced naturally in blood vessel linings and is used in a genetically engineered form to prevent damage to heart muscle following a heart attack and reduce neurological damage following ischemic stroke âabbreviation TPA. ADVERTISEMENT.
Causation principle refers to the relation between the cause or an event and the effect or a second event. The second event is the physical result of the first.      â¦ . Torrey Garcia.
It is almost a clichÃ© that correlation does not mean causation. The main fallacy in inferring causation from correlation is called the third variable problem and means that a third variable is responsible for the correlation between two other variables.