This would produce litters without EIC and a choice of dogs to progressively decrease the frequency of the E form of the DNM1 gene by future matings to N/N dogs. University of Minnesota. For EIC information go to the EIC Testing web site.
A nevus is a benign ( noncancerous) melanocytic tumor, more commonly called a mole. Nevi (the plural of nevus) are not usually present at birth but begin to appear in children and teenagers. Most moles will never cause any problems, but a person who has 50 or more moles is more likely to develop melanoma, the most aggressive form of skin cancer.
A benign tumor is a mass of cells (tumor) that lacks the ability to invade neighboring tissue or metastasize. These characteristics are required for a tumor to be defined as cancerous and therefore benign tumors are non-cancerous. Also, benign tumors generally have a slower growth rate than malignant tumors and the tumor cells are usually more differentiated (cells have normal features). Benign tumors are typically surrounded by an outer surface (fibrous sheath of connective tissue) or remain with the epithelium.