One or more of the following symptoms indicate the deterioration of kidney function: 1  Itching. 2  Nausea, vomiting and loss of appetite. 3  Swollen ankles. 4  Tiredness and fatigue. 5  Muscle cramps. 6  Change in urine volume, (there can be an increase or decrease in the amount of urine passed daily) 7  Shortness of breath. 8  Sleep disturbance.
Reference Pricing. With reference-based pricing, employers set a pricing cap on the maximum amount that they will cover for certain medical services that have wide cost variations, such as knee and hip replacement surgery.
In health-related fields, a reference range or reference interval is the range of values for a physiologic measurement in healthy persons (for example, the amount of creatinine in the blood, or the partial pressure of oxygen).t is a basis for comparison (a frame of reference) for a physician or other health professional to interpret a set of test results for a particular patient. Some important reference ranges in medicine are reference ranges for blood tests and reference ranges for urine tests.