The syndrome is caused by the misfolding of fibrillin-1, a glycoprotein which forms elastic fibers in connective tissue and contributes to cell signaling activity by binding to and sequestering transforming growth factor beta (TGF-Î²).arfan syndrome is caused by mutations in the FBN1 gene on chromosome 15, which encodes fibrillin-1, a glycoprotein component of the extracellular matrix.
pomegranate meaning, definition, what is pomegranate: a round, thick-skinned fruit containing a mass of red seeds and a lot of juice. Learn more.
Pomegranates are known for their strong health benefits, tangy red seeds and resistance to most pests and diseases. This tasty and popular fruit grows on trees, which can range in size and appearance from a squat, 3-foot shrub-like tree to a more traditional-looking, 30-foot-tall tree.