The syndrome is caused by the misfolding of fibrillin-1, a glycoprotein which forms elastic fibers in connective tissue and contributes to cell signaling activity by binding to and sequestering transforming growth factor beta (TGF-Î²).arfan syndrome is caused by mutations in the FBN1 gene on chromosome 15, which encodes fibrillin-1, a glycoprotein component of the extracellular matrix.
pomegranate meaning, definition, what is pomegranate: a round, thick-skinned fruit containing a mass of red seeds and a lot of juice. Learn more.
The pomegranate fruit season in the Northern Hemisphere is from September through February, but in the Southern Hemisphere, it runs from March through May.In the state of California in the United States, the season of the pomegranate is from October through January.uring the season, the pomegranate trees and fruit must be protected from insects. The most effective methods used to be with harmful chemicals, but the growers found that those would also damage a percentage of the fruit, so they switched to organic compounds.