The syndrome is caused by the misfolding of fibrillin-1, a glycoprotein which forms elastic fibers in connective tissue and contributes to cell signaling activity by binding to and sequestering transforming growth factor beta (TGF-Î²).arfan syndrome is caused by mutations in the FBN1 gene on chromosome 15, which encodes fibrillin-1, a glycoprotein component of the extracellular matrix.
pomegranate meaning, definition, what is pomegranate: a round, thick-skinned fruit containing a mass of red seeds and a lot of juice. Learn more.
Pomegranates are also long-lived. There are specimens in Europe that are known to be over 200 years of age. The vigor of a pomegranate declines after about 15 years, however. Foliage: The pomegranate has glossy, leathery leaves that are narrow and lance-shaped.