DRUG CLASS AND MECHANSIM: Colchicine is an oral drug used for treating acute gout and familial Mediterranean fever (FMF). In acute gout there is severe inflammation in response to the presence of uric acid crystals that form in bony joints.This causes severe pain, redness, and swelling of the affected joint(s).RESCRIBED FOR: Colchicine is used for the treatment of acute flares of gout. It also is used for treating FMF in adults and children 4 years of age or older.
Systemic mean arterial pressure (MAP) is defined as the mean perfusion pressure throughout the cardiac cycle. MAP is sensed by baroreceptors located in the carotid sinuses and the arch of the aorta. These receptors control arterial pressure mainly by adjusting heart rate and arteriolar vessel radius.
ABG-A is a normal blood gas in room air. ABG-B (pH 7.20, pCO2 60, pO2 70, bicarb 24, BE -3) shows a patient with acute respiratory failure. The pH is less than 7.40 which means that the patient has an acidosis. The pCO2 is very high so this is the respiratory component which contributes to the acidosis.