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Common simvastatin side effects may include: 1  headache; 2  constipation, nausea, stomach pain; or. 3  cold symptoms such as stuffy nose, sneezing, sore throat.
No adjustment is necessary for atorvastatin (Lipitor) or fluvastatin (Lescol). The statins differ in their ability to cause side effects. Skeletal muscle toxicity such as rhabdomyolysis may occur when certain drugs are given with statins which causes an increase in the concentration of statins.