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In the process, the nucleus of an egg is inserted into the cytoplasm of an egg from a donor female which has had its nucleus removed, but still contains the donor female's mtDNA. The composite egg is then fertilized with the male's sperm.
In Anopheles gambiae, all 350 copies are together, side-by-side on the X chromosome, he told BBC News. When sperm are produced normally, in mosquitoes or in humans, 50% contain an X chromosome and 50% a Y chromosome. When they fuse with an egg these produce female and male embryos, respectively.In the new mosquitoes, the X-attacking endonuclease is turned on specifically during sperm formation.heoretically, if you have it on the Y, Prof Crisanti added, one single individual could knock out an entire population.. In fact, Dr Windbichler and Prof Crisanti showed in another recent paper that this type of gene insertion on the mosquito Y chromosome is perfectly achievable.