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Kittens are generally vaccinated against FeLV around 8 to 9 weeks of age. A booster vaccination is given 3 to 4 weeks later, according to the vaccine label, followed by boosters each year as long as the risk for exposure remains. Similarly, vaccination against FIV can begin when kittens are around 8 weeks of age. Two additional boosters are given 2 to 3 weeks apart, followed by boosters each year as long as the risk for exposure remains. Cats that go outside are at greater risk for exposure to FeLV and FIV compared with cats that stay indoors.
Since a lot of cats will be tested who won't have the disease and only a small number of cats will be tested who do have the disease it becomes somewhat likely that a test that is positive is inaccurate. All cats should be tested at least twice when they show up positive on feline leukemia testing. The other problem is that cats can be negative on a test for feline leukemia and then become positive due to recurrence of a suppressed infection, a new infection or because of a false negative result to begin with.