Adenocarcinoma of the esophagus, the cancer that is especially associated with Barrett's esophagus, is currently the most rapidly rising cancer in the U.S., with a sixfold increase in cases during the past 30 years, according to the National Cancer Institute.
For other uses, see Nero Wolfe (disambiguation). Nero Wolfe is a fictional character, a brilliant, oversize, eccentric armchair detective created in 1934 by American mystery writer Rex Stout. Wolfe was born in Montenegro and keeps his past murky.
Two subspecies are recognized, these being Canis dirus guildayi and Canis dirus dirus. The species probably descended from Armbruster's wolf (Canis armbrusteri) and evolved from it in North America. The largest collection of dire wolf fossils has been obtained from the Rancho La Brea Tar Pits in Los Angeles, California.