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Human immunodeficiency virus infection and acquired immune deficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV). Following initial infection, a person may experience a brief period of influenza-like illness.
Introduction. Changing HIV-1 virulence over the course of the AIDS epidemic carries implications for the future treatment and prevention of HIV/AIDS. Virulence is defined as the severity of a disease; for HIV, virulence is defined as the rate of progression to AIDS in untreated infections.