The immune system can distinguish between normal, healthy cells and unhealthy cells by recognizing a variety of danger cues called danger-associated molecular patterns (DAMPs). Cells may be unhealthy because of infection or because of cellular damage caused by non-infectious agents like sunburn or cancer.he immune system can distinguish between normal, healthy cells and unhealthy cells by recognizing a variety of danger cues called danger-associated molecular patterns (DAMPs). Cells may be unhealthy because of infection or because of cellular damage caused by non-infectious agents like sunburn or cancer.
Time-weighted return. The time-weighted return (TWR) (or true time-weighted rate of return (TWRR)) is a method of calculating investment return. To apply the time-weighted return method, combine the return over sub-periods, by compounding them together, resulting in the overall period return. The rate of return over each different sub-period is weighted according to the duration of the sub-period.
If the date and time of the current instance is earlier than value, the method returns a TimeSpan object that represents a negative time span. That is, the value of all of its non-zero properties (such as Days or Ticks) is negative. TheSubtract(DateTime) method does not consider the value of the Kind property of the two DateTime values when performing the subtraction. Before subtracting DateTime objects, ensure that the objects represent times in the same time zone. Otherwise, the result will include the difference between time zones.