The syndrome is caused by the misfolding of fibrillin-1, a glycoprotein which forms elastic fibers in connective tissue and contributes to cell signaling activity by binding to and sequestering transforming growth factor beta (TGF-Î²).arfan syndrome is caused by mutations in the FBN1 gene on chromosome 15, which encodes fibrillin-1, a glycoprotein component of the extracellular matrix.
pomegranate meaning, definition, what is pomegranate: a round, thick-skinned fruit containing a mass of red seeds and a lot of juice. Learn more.
The Growing Popularity of Pomegranate Jewelry and Pomegranate Gifts Because the pomegranate is so rich in history and symbolism, it is represented in modern culture in everything from pomegranate jewelry to all kinds of pomegranate gifts, which are appropriate for many occasions.