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Avonex for Multiple Sclerosis. Avonex, a formulation of interferon beta-1a, is an injectable medication from Biogen approved by the U.S. Food and Drug Administration (FDA) for patients with relapsing forms of multiple sclerosis (MS) who have had a first attack and show lesions on an MRI. Avonex injections help reduce the number of flare-ups and MS disease progression. How Avonex Works. Interferon beta-1a, the active ingredient in Avonex, is a protein found naturally in the body. It is a signaling molecule produced by cells and is used for communication.
Glatiramer acetate (marketed as Copaxone) appears to trick the immune system into activating certain immune cells normally associated with the damage in MS. These cells go into the brain and, upon reaction with myelin base protein, reduce the inflammation at the MS lesions. In a sense, it works the way allergy desensitization injections do.