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These drugs lower the white blood cell count to a greater degree than the counts of other blood cells â red blood cells and platelets â although these are commonly affected, too. Fortunately, the effect of these drugs on the white blood cell count is usually both predictable and short-lived. The white cell count generally falls below the normal range about seven to ten days after a chemotherapy treatment and recovers within about a week after that.
Autoimmune diseases that attack your white blood cells can also lead to a low WBC count. Several different prescribed drugs, including chemotherapy, are known to decrease WBC production or destroy WBCs. A low WBC count can be serious because it increases your risk of developing a potentially life-threatening infection.