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Laboratory Tests. Laboratory tests are performed to detect, identify, evaluate, and monitor meningitis and encephalitis. These tests are performed in order to: 1  Distinguish these infections from other conditions with similar symptoms.
If the mono test is persistently negative, a test specific for EBV antibodies may be used to help confirm or rule out the presence of an EBV infection. A strep test may also be ordered along with a mono test to determine whether a person's sore throat is due to strep throat (group A streptococcal infection) instead of or in addition to mononucleosis.