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Eighteen male patients with primary syphilis were randomly assigned to one of the following treatment schedules: ceftriaxone (3 g in a single intramuscular [im] injection), ceftriaxone (2 g im daily for two days), ceftriaxone (2 g im daily for five days), and benzathine penicillin (2.4 X 10(6) units in a single im injection).
Syphilis is serious â but it can be cured. Syphilis is a really common STD. Syphilis is spread through vaginal, anal, and oral sex. Syphilis causes sores on your genitals (called chancres). The sores are usually painless, but they can easily spread the infection to other people. You get syphilis from contact with the sores. A lot of people with syphilis donât notice the sores and feel totally fine, so they might not know they have it.