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I can't tell you how long the initial breakout will last, because your skin is not the same as mine. I will say that you should give it the 12 weeks. The manufacturer says it may take up to 12 weeks, so until 12 weeks have passed, you can't reach a real verdict.'m currently using Epiduo which is a mixture of Adapalene (Differin) and Benzoyl Peroxide. My initial breakout started after a week of using the cream and I'm still going through it-and I've been using it for four weeks now. As far as I know this is normal and I heard it can last anything between two and six weeks.
How long a rash lasts depends on its cause. However, most rashes usually disappear within a few days. For example, the rash of a roseola viral infection usually lasts 1 to 2 days, whereas the rash of measles disappears within 6 to 7 days. Rashes caused by an antibiotic allergy may last 3 to 14 days, whereas diaper rash almost always clears up within 1 week (if diapers are changed frequently). Rashes resulting from lupus or dermatomyositis may last for an extended period of time.