The annual cost of providing HIV treatment and care in the UK could be as high as Â£758 million by 2013, investigators suggest in the online journal PLoS One. When the researchers included social care into their calculations, the 2013 cost was estimated to be well over Â£1000 million.
Chlorpheniramine maleate is part of a class of drugs called antihistamines. Specifically, it is an H1 receptor antagonist. This means that it blocks a specific type of histamine receptor in the body known as H1 receptors.
Cis-(+)-sertraline hydrochloride form-II is obtained from cis-(+)-sertraline mandelate by conversion of mandelate salt to cis-(+)-sertraline base and further dissolving base in a solvent and reacting with hydrogen chloride. The process does not need any seeding.UMMARY OF THE INVENTION. The present invention discloses a novel method for the preparation of racemic sertraline starting from the known tetralone and cis(+) sertraline hydrochloride form II from cis(+) sertraline mandelate.