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The bloodâtestis barrier is a physical barrier between the blood vessels and the seminiferous tubules of the animal testes.hen the bloodâtestes barrier is breached, and sperm enters the bloodstream, the immune system mounts an autoimmune response against the sperm. The anti-sperm antibodies generated by the immune system can bind to various antigenic sites on the surface of the sperm.
Blood-brain barrier. A blockade of cells separating the circulating blood from elements of the central nervous system (CNS); it acts as a filter, preventing many substances from entering the central nervous system.he blood-brain barrier prevents or slows the passage of some drugs and other chemical compounds, radioactive ions, and disease-causing organisms such as viruses from the blood into the central nervous system.