Doors 32 Documentation. Our longstanding and much loved Doors32 Software is now available only via download from Keri's web site or special order, but is still free of charge. It will continue to be available as long as customers ask for it and computers with compatible operating systems exist.
Cell biology The reduction of a cellâs response to a hormone or other ligand by internalizing its cognate receptor and degrading it within a coated pit; downregulation is a mechanism by which receptors respond to an excess of ligands.
The GABAA receptor (GABAAR) is an ionotropic receptor and ligand-gated ion channel. Its endogenous ligand is Î³-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the central nervous system.Upon activation, the GABA A receptor selectively conducts Clâ through its pore, resulting in hyperpolarization of the neuron.ts endogenous ligand is Î³-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the central nervous system. Upon activation, the GABA A receptor selectively conducts Clâ through its pore, resulting in hyperpolarization of the neuron.