Feedback inhibition can have a major impact if it shuts off, or if the inhibitor product is synthesized despite the inhibition. For example, cholesterol is synthesized in the body and is regulated by silencing the enzyme that uses the sterol compounds to produce cholesterol.
Fort-de-France (French pronunciation: [fÉÊ dÉ fÊÉÌs]) is the capital of France's Caribbean overseas department of Martinique. It is also one of the major cities in the Caribbean. Exports include sugar, rum, tinned fruit, and cacao
However, in 1695, the Comte de Frontenac ordered the fort rebuilt, and it was occupied by a small garrison until 1745. In 1758, the British under Colonel John Bradstreet captured the fort and it remained in British possession until the end of the War of 1812, when it was deemed obsolete and was gradually demolished.