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Several antibiotics are currently used to treat UTIs. If you have a UTI that does not involve your kidneys, your doctor may prescribe one of several drugs, such as: 1  Macrobid (nitrofurantoin monohydrate)  Bactrim (trimethoprim and sulfamethoxazole)
Antibiotics also prevent UTIs. The doctor might prescribe preventive antibiotic therapy for: 1  Women who have recurrent UTIs (at least two UTIs in 6 months or three UTIs in 1 year). 2  Pregnant women who had recurrent UTIs before getting pregnant or during pregnancy.