Doors 32 Documentation. Our longstanding and much loved Doors32 Software is now available only via download from Keri's web site or special order, but is still free of charge. It will continue to be available as long as customers ask for it and computers with compatible operating systems exist.
Cell biology The reduction of a cellâs response to a hormone or other ligand by internalizing its cognate receptor and degrading it within a coated pit; downregulation is a mechanism by which receptors respond to an excess of ligands.
Thyroid Hormone Receptors. Thyroid hormones act by binding to cytosolic receptors of the steroid-thyroid hormone receptor superfamily (nuclear receptors) identified as thyroid hormone receptors (TR). There are two TR receptors designated TRÎ± and TRÎ² encoded by the THRA and THRB genes, respectively.ecause of its relatively lower potency, testosterone is sometimes considered to be a prohormone. Synthesis of the male sex hormones in Leydig cells of the testis. P450SSC, 3Î²-DH, and P450c17 are the same enzymes as those needed for adrenal steroid hormone synthesis.