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1 Skin diseases like eczema and scabies can also cause red itchy palms. 2  Bumps and exfoliation of palmer skin is observed in these conditions. 3  Bacterial and fungal infection of palms can be a reason for itchy palms. 4  Dry skin of palms can be a reason for itchy palms.
Answer. The most common cause of small bumps on the palms of the hands is something called dyshidrotic eczema. In this condition, the skin on the palms (or the soles of the feet) becomes irritated, and the initial symptoms are small firm blisters under the skin, about the size of a pinhead, which may be either whitish or clear in appearance.