About 3%-5% of people become carriers of the bacteria after the acute illness. Others suffer a very mild illness that goes unrecognized. These people may become long-term carriers of the bacteria -- even though they have no symptoms -- and be the source of new outbreaks of typhoid fever for many years.thers suffer a very mild illness that goes unrecognized. These people may become long-term carriers of the bacteria -- even though they have no symptoms -- and be the source of new outbreaks of typhoid fever for many years.
This is the parent strand of DNA which runs in the 3' to 5' direction toward the fork, and it's able to be replicated continuously by DNA polymerase. The other strand is called the lagging strand. This is the parent strand which runs in the 5' to 3' direction toward the fork, and it's replicated discontinuously. Now let's talk about the difference between continuous and discontinuous replication.
To explain how the synthesis of both strands is coordinated, an asymmetric dimer of DNA polymerases and associated factors has been proposed first for prokaryotic DNA replication (McHenry 1988) and subsequently extended for eukaryotes (Tsurimoto and Stillman 1989).nvestigating how the distinct activities required for DNA synthesis are organized within the cell nucleus relates to the larger issue of understanding how DNA replication is regulated on a cellular level. A cell must duplicate its entire genome once and only once every time it divides.