Fig. 2b shows an overlay of spectra (mass window from 3,000 to 5,000 Da) resulting from C-specific cleavage of the IGF2/H19 region. Signals representing methylation events at CpGs 6-8, 10-12, 15, and 16 of the IGF2/H19 region are shown.
To calculate the cost of the chromium. contained in this material, remember that chromic oxide is. 68.42% chromium. Consequently, 1 ton of this material then. contains between 0.287 and 0.308 ton of chromium yielding. a unit value of between $325 and $348 per ton of chromium.
Hexavalent chromium is also one of the substances whose use is restricted by the European Restriction of Hazardous Substances Directive. The LD50 for chromium(VI) ranges between 50 and 150 mg/kg.In the body, chromium(VI) is reduced by several mechanisms to chromium(III) already in the blood before it enters the cells.The chromium(III) is excreted from the body, whereas the chromate ion is transferred into the cell by a transport mechanism, one by which sulfate and phosphate ions also enter the cell.ecause of the specific transport mechanisms, only limited amounts of chromium(III) enter the cells. Several in vitro studies indicated that high concentrations of chromium(III) in the cell can lead to DNA damage. Acute oral toxicity ranges between 1900 and 3300 Âµg/kg.