The syndrome is caused by the misfolding of fibrillin-1, a glycoprotein which forms elastic fibers in connective tissue and contributes to cell signaling activity by binding to and sequestering transforming growth factor beta (TGF-Î²).arfan syndrome is caused by mutations in the FBN1 gene on chromosome 15, which encodes fibrillin-1, a glycoprotein component of the extracellular matrix.
pomegranate meaning, definition, what is pomegranate: a round, thick-skinned fruit containing a mass of red seeds and a lot of juice. Learn more.
In addition to their exotic, one-of-a-kind taste, pomegranates (Punica granatum), which thrive in U.S. Department of Agriculture plant hardiness zones 8 through 11, bear a striking form: a near-hexagonal shape with a crown-like calyx protruding from the blossom end, and a leathery, crimson skin pulled taut around a sac-filled interior.