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Pericarditis is swelling and irritation of the pericardium, which is the sac that surrounds your heart. Pericarditis usually doesn't cause serious problems. Most people get better in 7 to 10 days. When there are problems, they may include: 1  A buildup of fluid in the pericardial sac (pericardial effusion). 2  Sudden pressure on the heart and sudden difficulty pumping enough blood (called cardiac tamponade). 3  Constrictive pericarditis, which can occur when pericarditis comes back or becomes a longer-term problem.
Complications of Pericarditis Two serious complications of pericarditis are cardiac tamponade and chronic constrictive pericarditis. 1  Cardiac tamponade occurs if too much fluid collects in the pericardium (the sac around the heart). 2  Chronic constrictive pericarditis is a rare disease that develops over time.