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Definition of CEREBRAL HEMISPHERE. : either of the two hollow convoluted lateral halves of the cerebrum â see brain illustration.
> Langbrain > Brain > Telencephalon. Telencephalon. The Cerebral Hemispheres. The Telencephalon (the cerebral hemispheres) is the largest of the divisions of the human brain, and it is what subserves language â at least the aspects of language which are of interest to linguistics and most other people.