A heart attack happens when blood flow to the heart suddenly. becomes blocked and the heart canât get oxygen. quickly, the heart muscle fails to pump and begins to die. disease (CHD), also called coronary artery disease.
A co-receptor is a cell surface receptor that binds a signalling molecule in addition to a primary receptor in order to facilitate ligand recognition and initiate biological processes, such as entry of a pathogen into a host cell.n immunology in particular, the term co-receptor often describes a secondary receptor used by a pathogen to gain access to the cell, or a receptor that works alongside T cell receptors such as CD4, CD8, or CD28 to bind antigens or regulate T cell activity in some way.
G-protein-coupled receptors (GPCRâs): these are the largest of all the cell surface receptors. They activate membrane-bound, trimeric GTP binding proteins (G-proteins) which then activate either an enzyme or an ion channel (effector) in the plasma membrane, initiating a sequence of other effects.ell surface receptors are responsible for the binding of an extracellular signalling molecule and transduction of its messages into one or more intracellular signalling molecules, which changes the cellâs behaviour. A cell surface receptor exists intrinsically embedded in the plasma membrane.