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Eighteen male patients with primary syphilis were randomly assigned to one of the following treatment schedules: ceftriaxone (3 g in a single intramuscular [im] injection), ceftriaxone (2 g im daily for two days), ceftriaxone (2 g im daily for five days), and benzathine penicillin (2.4 X 10(6) units in a single im injection).
What causes syphilis? Bacteria cause syphilis. They usually enter the body through the tissues that line the throat, nose, rectum, and vagina. A person with syphilis who has a sore or a rash can pass the infection to others. An infected pregnant woman can also pass syphilis to her baby. Some things increase your chance of getting syphilis. They include: Having unprotected sex (such as not using condoms or not using them correctly). This risk is high among men who have unsafe sex with other men. Having more than one sex partner and living in an area where syphilis is common. Having a sex partner who has syphilis. Having sex with a partner who has many sex partners.