To generate random floating-point numbers whose lower bound is 0 but upper bound is greater than 1 (or, in the case of negative numbers, whose lower bound is less than -1 and upper bound is 0), multiply the random number by the non-zero bound.
Epigenetic Changes Can Cause Cancer. A transgene designed to attract methylation to the promoter of a tumor-suppressor gene leads to tumorigenesis in a mouse model.By Ashley P. Taylor | July 25, 2014. Changes in gene methylation alone can trigger cancer, according to a mouse study published today (July 25) in the Journal of Clinical Investigation. transgene designed to attract methylation to the promoter of a tumor-suppressor gene leads to tumorigenesis in a mouse model. By Ashley P. Taylor | July 25, 2014. Changes in gene methylation alone can trigger cancer, according to a mouse study published today (July 25) in the Journal of Clinical Investigation.
Unlike genetic changes in cancer, as we have previously discussed, epigenetic changes are potentially reversible. Reactivation of the silencing associated with promoter methylation for critical genes, such as p16, would be a highly desirable goal for reversing many aspects of the cancer cell phenotype.