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Kittens are generally vaccinated against FeLV around 8 to 9 weeks of age. A booster vaccination is given 3 to 4 weeks later, according to the vaccine label, followed by boosters each year as long as the risk for exposure remains. Similarly, vaccination against FIV can begin when kittens are around 8 weeks of age. Two additional boosters are given 2 to 3 weeks apart, followed by boosters each year as long as the risk for exposure remains. Cats that go outside are at greater risk for exposure to FeLV and FIV compared with cats that stay indoors.
Kitten shots are phenomenally important, and unvaccinated kittens succumb to feline panleukopenia at high rates. I therefore recommend that all cat owners diligently have their cats vaccinated (with the so-called FVRCP) at 6-8 weeks, 10-12 weeks, and 14-16 weeks. A booster should occur at one year of age. I do not recommend that any cat receive subsequent boosters any more often than every three years; many owners of indoor cats elect a 5-7 year period. The FVRCP is the most important vaccine kittens receive. There are two other vaccines that are in common use.