The immune system can distinguish between normal, healthy cells and unhealthy cells by recognizing a variety of danger cues called danger-associated molecular patterns (DAMPs). Cells may be unhealthy because of infection or because of cellular damage caused by non-infectious agents like sunburn or cancer.he immune system can distinguish between normal, healthy cells and unhealthy cells by recognizing a variety of danger cues called danger-associated molecular patterns (DAMPs). Cells may be unhealthy because of infection or because of cellular damage caused by non-infectious agents like sunburn or cancer.
Time-weighted return. The time-weighted return (TWR) (or true time-weighted rate of return (TWRR)) is a method of calculating investment return. To apply the time-weighted return method, combine the return over sub-periods, by compounding them together, resulting in the overall period return. The rate of return over each different sub-period is weighted according to the duration of the sub-period.
As the days grow colder and shorter, it's also time for the annual confusion on when to change our clocks, if we're in a state that observes daylight saving time: When do we do that? Is it forward or back? Daylight saving time ends this year on Sunday, Nov. 6. Officially speaking, clocks should be turned back at 2 a.m., but many people do that before they go to bed Saturday night -- or get up in the morning and find they're an hour early for everything. Spring -- forward. Fall -- back. When in doubt, check your cell phone, which should change automatically. Here are some common questions about daylight saving time and its origins. What is daylight saving time? It's a period of time during the year in which clocks are moved one hour forward. When ...