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Common simvastatin side effects may include: 1  headache; 2  constipation, nausea, stomach pain; or. 3  cold symptoms such as stuffy nose, sneezing, sore throat.
Effects on cholesterol levels. The effects of rosuvastatin on LDL cholesterol are dose-related. Higher doses were more efficacious in improving the lipid profile of patients with hypercholesterolemia than milligram-equivalent doses of atorvastatin and milligram-equivalent or higher doses of simvastatin and pravastatin.