NEW YORK (Reuters Health) â Long-term treatment of systemic lupus erythematosus (SLE) with hydroxychloroquine, initiated soon after disease onset, is protective against renal damage, according to study findings presented this week at the American College of Rheumatology Annual Scientific Meeting in San Francisco.
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The lumbar spine (lower back) is a remarkably complex structure. The L4-L5 are the two lowest vertebrae in the lumbar spine, and together with the attached disc, joints, nerves and soft tissues, it provides a variety of functions, including supporting the upper body and allowing motion in multiple directions. The back of the L4-L5 segment has a nerve that passes through it, from inside the spinal canal down through the back of each leg (as part of the sciatic nerve).