Definition of TISSUE PLASMINOGEN ACTIVATOR. : a clot-dissolving enzyme with an affinity for fibrin that is produced naturally in blood vessel linings and is used in a genetically engineered form to prevent damage to heart muscle following a heart attack and reduce neurological damage following ischemic stroke âabbreviation TPA.ADVERTISEMENT. a clot-dissolving enzyme with an affinity for fibrin that is produced naturally in blood vessel linings and is used in a genetically engineered form to prevent damage to heart muscle following a heart attack and reduce neurological damage following ischemic stroke âabbreviation TPA. ADVERTISEMENT.
Causation principle refers to the relation between the cause or an event and the effect or a second event. The second event is the physical result of the first.      â¦ . Torrey Garcia.
When looking at the relationship between two things, correlation and causation are concepts that are often confused. Correlation refers to things that appear to have some form of consistent relationship, i.e. one item increases at the same time the other increases also.