Definition of TISSUE PLASMINOGEN ACTIVATOR. : a clot-dissolving enzyme with an affinity for fibrin that is produced naturally in blood vessel linings and is used in a genetically engineered form to prevent damage to heart muscle following a heart attack and reduce neurological damage following ischemic stroke âabbreviation TPA.ADVERTISEMENT. a clot-dissolving enzyme with an affinity for fibrin that is produced naturally in blood vessel linings and is used in a genetically engineered form to prevent damage to heart muscle following a heart attack and reduce neurological damage following ischemic stroke âabbreviation TPA. ADVERTISEMENT.
Causation principle refers to the relation between the cause or an event and the effect or a second event. The second event is the physical result of the first.      â¦ . Torrey Garcia.
Subtraction in mathematics means you are taking something away from a group or number of things. When you subtract, what is left in the group becomes less. An example of a subtraction problem is the following: 5 - 3 = 2. Notice that there are three parts to the subtraction problem shown. The part you start with is called the minuend.