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Driving distance from Winston-Salem, NC to Durham, NC. The total driving distance from Winston-Salem, NC to Durham, NC is 80 miles or 129 kilometers. Your trip begins in Winston-Salem, North Carolina. It ends in Durham, North Carolina.
Nearest major airport to Winston-Salem, North Carolina: The closest major airport to Winston-Salem, North Carolina is Piedmont Triad International Airport (GSO / KGSO). This airport is in Greensboro, North Carolina and is 23 miles from the center of Winston-Salem, NC. If you're looking for domestic flights to GSO, check the airlines that fly to GSO. Search for direct flights from your hometown and find hotels near Winston-Salem, NC, or scroll down for more international airports or domestic airports. You can also browse local airports if you're a pilot.