History in Annapolis. Annapolis is nothing if not historic. Transformative historical icons such as Jefferson, Franklin, and Washington have wandered Annapolisâ brick streets,...
LSD was first made in 1938. The scientist that made it did so using ergot. Ergot is a fungus that grows on grains, especially rye. The LSD was synthesized and then self-tested.Originally, it was thought that the drug could be used to help with circulation.he scientist that made it did so using ergot. Ergot is a fungus that grows on grains, especially rye. The LSD was synthesized and then self-tested. Originally, it was thought that the drug could be used to help with circulation.
LSD stands for  lyserg saeure diaethylamid  in the original German. In English, it is called lysergic acid diethylamide. Dr. Albert Hofmann, a Swiss chemist looking for a new headache treatment, first produced LSD in 1938. He first developed lysergic acid, a derivative of ergot, a fungus that grows on the rye plant. dose the size of a grain of salt can cause effects. LSD inhibits the movement of serotonin in the brain, which influences mood. LSD seems to work in the cerebral cortex of the brain, which is involved in mood, thought, and perception, and in the locus ceruleus of the brain, which coordinates sensory perceptions.