@Lin_Manuel That's Opetaia & I singing together, he in his language, I in mine. I was just supposed to be the demo vocal but they kept me. â Lin-Manuel Miranda (@Lin_Manuel) November 7, 2016
The pregnenolone steal is a name given to the hormone production deficit of certain hormones when the stress hormones, cortisol and cortisone, are over-produced. All our hormones come from cholesterol, which converts into pregnenolone as the first step.f the body demands more cortisol because of stress, the body will convert more of the pregnenolone to cortisol at the expense of the other hormones (except progesterone, which is on the pathway to cortisol). The lowering of the testosterone and estrogen leg is called pregnenolone steal.
Interestingly, progesterone is made in your body from cholesterol and the progesterone your body produces has an identical molecular structure to the compounded natural bioidentical progesterone. First, your body turns cholesterol into pregnenolone. The Pregnenolone is then converted into progesterone and then your body then makes a cascade of other hormones that it needs from progesterone. Progesterone serves as a precursor not only to DHEA, testosterone and estrogen, but also to cortisol, the stress hormone. It is also the precursor to the sex hormones estrogen and testosterone and is secreted primarily by the ovaries in females and by the testes in men.