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Driving distance from Winston-Salem, NC to Durham, NC. The total driving distance from Winston-Salem, NC to Durham, NC is 80 miles or 129 kilometers. Your trip begins in Winston-Salem, North Carolina. It ends in Durham, North Carolina.
Travel time is an important point to know with the driving distance. Hence you might also want to know the Travel Time from Charlotte to Winston-Salem. This will help you estimate how much time you will spend travelling for the distance from Charlotte to Winston-Salem.