If served in a state or territory of the United States by a sheriff or United States marshal, or a deputy, by such personâs certificate with a statement as to date, place, and manner of service; 1  If by any other person, by the personâs affidavit thereof, with the same statement;
Colchicine, one 0.5 mg granule three times a day or one 0.6 mg tablet three times daily, should be administered for three days before and three days after surgery.
Doses should be decreased by 0.3 mg daily if side effects occur. DRUG INTERACTIONS: Several drugs reduce the breakdown and elimination of colchicine from the body by reducing the activity of enzymes that breakdown colchicine.