The cartilage rings are C-shaped because the back of the trachea presses against the esophagus. The cartilage opens at the esophagus and is replaced by connective tissue and muscle. This gives the esophagus space to allow food to be swallowed easily. The rings of the trachea are stacked one on top of the other, with a small space between them.
In 2014, a survey of the Australian working population revealed that the most common carcinogenic exposures in the workplace were solar ultraviolet radiation, diesel engine exhaust, environmental tobacco (second-hand) smoke, benzene, lead and silica.
Breathing of contaminated air is the most common way that workplace chemicals enter the body. Some chemicals, when contacted, can pass through the skin into the blood stream. Less commonly, workplace chemicals may be swallowed accidentally if food or cigarettes (or hands) are contaminated.