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CRESTORÂ® (rosuvastatin calcium) may cause serious side effects, including: Muscle pain, tenderness and weakness (myopathy). Muscle problems, including muscle breakdown, can be serious in some people and rarely cause kidney damage that can lead to death.
A: Crestor (rosuvastatin) is a synthetic lipid-lowering agent. The most common side effects are headache, myalgia (muscle pain), abdominal pain, asthenia (loss or lack of bodily strength; weakness) and nausea. And other side effects include, stomach upset, heartburn, constipation, bloating and gas.ccording to the package insert, the most common side effects of Crestor are headache, muscle pain, abdominal pain, weakness, and nausea. All of the cholesterol-lowering drugs called statins are known to cause varying degrees of muscle pain and muscle weakness.