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Common simvastatin side effects may include: 1  headache; 2  constipation, nausea, stomach pain; or. 3  cold symptoms such as stuffy nose, sneezing, sore throat.
Although the statistical models suggest that the negative effect of simvastatin on these parameters is no longer significant after long-term administration of the drug, further research on the effect of chronic treatment will be needed to probe for longer-term effects.