The syndrome is caused by the misfolding of fibrillin-1, a glycoprotein which forms elastic fibers in connective tissue and contributes to cell signaling activity by binding to and sequestering transforming growth factor beta (TGF-Î²).arfan syndrome is caused by mutations in the FBN1 gene on chromosome 15, which encodes fibrillin-1, a glycoprotein component of the extracellular matrix.
pomegranate meaning, definition, what is pomegranate: a round, thick-skinned fruit containing a mass of red seeds and a lot of juice. Learn more.
As the tree matures, it will begin to produce fruit that matures on the tree; generally, fruit needs about six or seven months on the tree to be ready for picking. A pomegranate is mature when it makes a tinny, metallic sound when tapped with a finger.iming. Growing a pomegranate tree that produces fruit requires time and the proper conditions. During its first three years, a young, newly planted tree is unlikely to bear usable fruit, although it may have small fruits that drop before they reach maturity.