This began Carle's true career; Soon he was writing and illustrating his own stories. His first books as both author and illustrator were 1, 2, 3 to the Zoo and The Very Hungry Caterpillar (G.P. Putnam's Sons, 1969). Eric Carle's art is distinctive and instantly recognizable.
âKalbitor is the least expensive HAE product on a per-dose basis with a WAC [i.e., wholesale acquisition cost] of $3,117 versus Firazyr of $6,800 versus Berinert of $5,691. The total cost of treating an HAE attack with one of the products indicated for an acute attack will change based the site of service.â.
Acute intravenous toxicity of Berinert was performed in mice at 1500, 3000, and. 6000 IU/kg and in rats at 1000, 2000, and 3000 IU/kg. Berinert was well tolerated and. no signs of toxicity were observed up to the highest dose administered.