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Abstract. Ankylosing spondylitis (AS) is an inflammatory disorder that presents with arthritis of the axial skeleton, including sacroiliac joints. Vitamin D is a secosteroid hormone with a long-established role in calcium and phosphate homeostasis, and in the regulation of bone formation and resorption.bstract. Ankylosing spondylitis (AS) is an inflammatory disorder that presents with arthritis of the axial skeleton, including sacroiliac joints. Vitamin D is a secosteroid hormone with a long-established role in calcium and phosphate homeostasis, and in the regulation of bone formation and resorption.
What is ankylosing spondylitis? Ankylosing spondylitis is a painful and progressive type of arthritis where some or all of the joints and bones of the spine fuse together. Ankylosing spondylitis cannot be cured and the symptoms can range from back pain and stiffness to long-term disability. Ankylosing spondylitis is estimated to affect around 200,000 people in the UK.