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Medical Definition of phthisis bulbi. : wasting and shrinkage of the eyeball following destructive diseases of the eye (as panophthalmitis)
10 hilariously insightful foreign words. The word phthisis, pronounced âTIE-sis,â is an ancient Greek medical term that was used to describe any disease of which the main symptom is atrophy or wasting of some kind.hthisis bulbi describes the shrunken appearance of an eye that has wasted as a result of ocular disease or injury. A wasted eye typically does not function.