In people with type 2 diabetes, NovoLog may be used with another type of insulin or with oral diabetes medicines. Insulin aspart was approved by the FDA in the year 2000 and is manufactured by Novo Nordisk.t's a short-acting, manufactured version of human insulin that lowers sugars in the blood. The medication works by replacing insulin that's normally produced by the body, helping move sugar from the blood into other areas of the body, and stopping the liver from producing more sugar.
WebMD News Archive. June 2, 2010 -- The FDA has approved twice-a-year Prolia (denosumab) injections to treat osteoporosis in patients at high risk of fracture. Prolia is a so-called monoclonal antibody -- a fully human, lab-produced antibody that inactivates the body's bone-breakdown mechanism.
Denosumab (Proliaâ¢, Xgevaâ¢) is a fully human monoclonal antibody against receptor activator of nuclear factor Îº-Î² ligand (RANKL) and inhibits its action on the surface receptors expressed on osteoclasts. Hepatic Impairment: clinical studies have not been conducted to evaluate the effect of hepatic impairment on the pharmacokinetics of denosumab. Drug Availability. â¢ Prolia: single-use prefilled syringe containing 60 mg in a 1 mL solution and single-use vial containing 60 mg in a 1 mL solution.