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Consequently, the incidence of VTE in the absence of. prophylaxis ranges from 40% to 60% (venographic rates) 7 to 14 days after major orthopedic surgery.1,11 The rate of. DVT during the same period is approximately 50% (Table.
Prophylactic platelet transfusion should be reserved for patients having major elective nonneuraxial surgery with a platelet count less than 50,000 cells/uL. For neurosurgery, platelets are usually transfused prophylactically for a preprocedure platelet count below 100,000 cells/uL. Prophylactic platelet transfusions are not recommended for patients with normal platelet counts who are undergoing cardiac surgery with cardiopulmonary bypass.