According to the American Psychiatric Association (APA) Practice Guidelines for the Treatment of Patients with Bipolar Disorder, biochemical hypothyroidism develops in 5% to 35% of patients with bipolar disorder, usually within 6 to 18 months of lithium treatment initiation.
The longest-surviving dynasty in the world is the Imperial House of Japan, the Yamato dynasty, whose reign is traditionally dated to 660 BC.
Japan's royal family is the longest running royal family in the world....but, that being said, it is questionable whether 8 people out of 10 would be able to pick the Emperor's face out of a lineup. The UK Queen has travelled to the ends of the world and back. Her face would be recognized instantly by many, many more people.