The origin of irregardless is not known for certain, but the speculation among references is that it may be a blend, or portmanteau word, of the standard English words irrespective and regardless. The blend creates a word with a meaning not predictable from the meanings of its constituent morphemes.
Tramadol is a Schedule IV Controlled Substance in Ohio Effective September 1. Source: Ohio State Board of Pharmacy. Effective Monday, September 1, tramadol and products containing tramadol will be classified as Schedule IV controlled substances in the state of Ohio pursuant to Ohio Administrative Code 4729-11-03.
The Drug Enforcement Administration (DEA) has officially declared tramadol as a Class IV substance, including its salts, isomers, and salts of isomers. The abuse potential of tramadol is comparable to the schedule IV controlled substance propoxyphene; 2  Tramadol has a currently accepted medical use in treatment in the U.S. Tramadol and other tramadol-containing products are approved for marketing by the FDA to manage moderate to moderately severe pain; and,