Granulomatosis with polyangiitis (formerly known as Wegener granulomatosis) is characterized by necrotizing granulomatous inflammation, small- and medium-sized vessel vasculitis, and focal necrotizing glomerulonephritis, often with crescent formation.
Brand name: Coumadin. Side effects are often related to abnormal bleeding. These include bruising easily, nosebleeds, bleeding from your gums, bleeding from cuts that takes a long time to stop, and heavier than normal menstrual bleeding. Warfarin is used to treat and prevent blood clots that might result in heart attack, stroke, or death.
How Does Warfarin Work? The formation of a clot in the body is a complex process that involves multiple substances called clotting factors. Warfarin decreases the bodyâs ability to form blood clots by blocking the formation of vitamin Kâdependent clotting factors.