During relaxation of the heart (diastole) the left ventricle of the heart fills with blood returning from the lungs. The left ventricle then contracts and pumps blood into the arteries (systole). The blood pressure in the arteries during contraction of the ventricle (systolic pressure) is higher because blood is being actively ejected into the arteries. It is lower during relaxation of the ventricle (diastolic pressure) when no blood is being ejected into the arteries.
The Premarin family of drugs contains estrogenic compounds that are made from the urine of pregnant mares. Thatâs where the name is derived from: PRE gnant MA resâ ur IN e = Premarin. Any HRT with Prem in the brand name is likely to contain conjugated equine (o)estrogen (CEE).
When treating symptoms of menopause, your doctor may start you off with 0.3 mg of Premarin each day, then increase the dose to the lowest possible dose that controls your symptoms. Your doctor might tell you to take Premarin every day for 25 days and then stop taking it for the last 5 days in the 30-day cycle. If you have a uterus, your doctor may also have you take progestin for 10 to 14 days during your cycle to help reduce the risk of certain cancers.