During relaxation of the heart (diastole) the left ventricle of the heart fills with blood returning from the lungs. The left ventricle then contracts and pumps blood into the arteries (systole). The blood pressure in the arteries during contraction of the ventricle (systolic pressure) is higher because blood is being actively ejected into the arteries. It is lower during relaxation of the ventricle (diastolic pressure) when no blood is being ejected into the arteries.
The Premarin family of drugs contains estrogenic compounds that are made from the urine of pregnant mares. Thatâs where the name is derived from: PRE gnant MA resâ ur IN e = Premarin. Any HRT with Prem in the brand name is likely to contain conjugated equine (o)estrogen (CEE).
Estrogen is a female sex hormone produced by the ovaries. Estrogen is necessary for many processes in the body. Premarin is used to treat symptoms of menopause such as hot flashes, and vaginal dryness, burning, and irritation. Other uses include prevention of osteoporosis in postmenopausal women, and replacement of estrogen in women with ovarian failure or other conditions that cause a lack of natural estrogen in the body. Premarin is sometimes used as part of cancer treatment in women and men.