According to the American Psychiatric Association (APA) Practice Guidelines for the Treatment of Patients with Bipolar Disorder, biochemical hypothyroidism develops in 5% to 35% of patients with bipolar disorder, usually within 6 to 18 months of lithium treatment initiation.
The longest-surviving dynasty in the world is the Imperial House of Japan, the Yamato dynasty, whose reign is traditionally dated to 660 BC.
It lasted from 1122-211 BC. The Qin Dynasty was the shortest ruling Chinese dynasty. It lasted only 15 years. Emperor Kangxi, the second emperor of Qing Dynasty, was the longest-reigning emperor in the history of China. He ruled China for 61 years during the years from 1661 to 1722. Emperor Modi of Jin (1234), the last emperor of Jin Dynasty, was the shortest-reigning emperor in the history of China.