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1 Believe it or not, hair loss (alopecia) due to chemotherapy is one of the most distressing side effects of chemo treatments.  Hair loss happens because the chemotherapy affects all cells in the body, not just the cancer cells. The lining of the mouth, stomach, and the hair follicles are especially sensitive because those cells multiply rapidly just like the cancer cells.
Female hormones. Just as pregnancy hormone changes can cause hair loss, so can switching or going off birth-control pills. This can also cause telogen effluvium, and it may be more likely if you have a family history of hair loss. The change in the hormonal balance that occurs at menopause may also have the same result. âThe androgen (male hormone) receptors on the scalp becoming activated,â explains Mark Hammonds, MD, a dermatologist with Scott & White Clinic in Round Rock, Texas.