Clonidine should not be used by people who have a known allergy to this drug. If a person has underlying depression, clonidine should be used with caution and under close physician supervision. Clonidine should not be abruptly withdrawn but rather, slowly decreased over several days to avoid withdrawal symptoms.
Three ways mutations can occur in genes are: 1. Insertion: Extra DNA nucleoties are added to the DNA strand. 2. Deletion: DNA nucleotides are deleted, therefore, changing the â¦ DNA sequence. 3. Translocation: parts of chromosomes are exchanged.or example, this can happen during crossover during the formation of gametes. Substitution mutations happen when one nucleotide (the smallest unit of DNA) is replaced by another. These are caused by a number of chemicals that look like something in between both of those nucleotides.
Altering nucleotide sequences most often results in nonfunctioning proteins. Mutations cause changes in the genetic code that lead to genetic variation and the potential to develop disease. Gene mutations can be generally categorized into two types: point mutations and base-pair insertions or deletions.Point mutations are the most common type of gene mutation.ommon errors that occur during cell division can result in point mutations and frame shift mutations. Mutations during cell division can lead to replication errors which can result in the deletion of genes, translocation of portions of chromosomes, missing chromosomes, and extra copies of chromosomes.