Clonidine should not be used by people who have a known allergy to this drug. If a person has underlying depression, clonidine should be used with caution and under close physician supervision. Clonidine should not be abruptly withdrawn but rather, slowly decreased over several days to avoid withdrawal symptoms.
Three ways mutations can occur in genes are: 1. Insertion: Extra DNA nucleoties are added to the DNA strand. 2. Deletion: DNA nucleotides are deleted, therefore, changing the â¦ DNA sequence. 3. Translocation: parts of chromosomes are exchanged.or example, this can happen during crossover during the formation of gametes. Substitution mutations happen when one nucleotide (the smallest unit of DNA) is replaced by another. These are caused by a number of chemicals that look like something in between both of those nucleotides.
Mutation can result in many different types of change in sequences. Mutations in genes can either have no effect, alter the product of a gene, or prevent the gene from functioning properly or completely. Mutations can also occur in nongenic regions.