Infusion Reactions. 1  Simponi Aria: In the controlled phase of Trial 1 (through week 24), 1.1% of Simponi Aria infusions were associated with an infusion reaction compared with 0.2% of infusions in the control group. Rash was the most common infusion reaction. No serious infusion reactions were reported.
Rats who have high levels of cortisol and chronic stress had fewer neurons overall but a big increase in oligodendrocytes. By blocking the equivalent of cortisol receptors, the researchers discovered the process was tied to the stress hormone.âThis was absolutely not what we were expecting to find,â Kaufer said.he gray matter of the brain is densely packed with nerve cell bodies and is responsible for the brain's higher functions, such as thinking, computing, and decision-making. But gray matter is only half of the brain matter inside our headsâthe other half of brain volume is called white matter.
Cortisol & Adrenal Function. Cortisol is a life sustaining adrenal hormone essential to the maintenance of homeostasis. Called âthe stress hormone,â cortisol influences, regulates or modulates many of the changes that occur in the body in response to stress including, but not limited to: 1  Blood sugar (glucose) levels. 2  Fat, protein and carbohydrate metabolism to maintain blood glucose (gluconeogenesis). 3  Immune responses.