Full Definition of PERSECUTE. transitive verb. 1. : to harass or punish in a manner designed to injure, grieve, or afflict; specifically: to cause to suffer because of belief.
Note the presence of giant cells. The granulomatous lesions in this disorder are typically non-caseating. This is in constrast to TB granuloma which causes casating granuloma (slides with TB granuloma is uncommon in MRCOphth). A TB granuloma showing central necrosis (caseating granuloma) and the presence of giant cells.n addition, the macrophages may fuse together to form multinucleate giant cells (different types of inciting materials may produce different giant cells). Granulomatous lesion typically occurs when the usual acute inflammatory reaction involving neutrophils could not remove the inciting agent.
Lesion is a broad term, including wounds, sores, ulcers, tumors, cataracts and any other tissue damage. They range from the skin sores associated with eczema to the changes in lung tissue that occur in tuberculosis. Terms describing distribution of lesions. lesion may be described as benign, cancerous, gross, occult, or primary. (1) Any pathological or traumatic discontinuity of tissue or loss of function of a part; a wounded or damaged area; an anatomic or functional tissue defect; an area of abnormal tissue change.