Nucleic acids are linear polymers (chains) of nucleotides. Each nucleotide consists of three components: a purine or pyrimidine nucleobase (sometimes termed nitrogenous base or simply base), a pentose sugar, and a phosphate group. The substructure consisting of a nucleobase plus sugar is termed a nucleoside.
Other studies of Remicade and methotrexate indicate that the two medications together can successfully reduce symptoms of psoriasis and psoriatic arthritis, the researchers report. Studies of Humira and Enbrel in conjunction with methotrexate also revealed the combination to be more effective than the biologic alone.
What is Methotrexate? Methotrexate is an anti-inflammatory agent used to treat rheumatoid arthritis and other inflammatory conditions. It works by suppressing the blood cells that cause inflammation. It is a chemotherapy agent used to treat cancer, but in 1988, the FDA approved it to be used by rheumatoid arthritis patients (in much lower doses).