Definition and Etiology. Primary sclerosing cholangitis (PSC) is a chronic, progressive, cholestatic liver disease resulting from inflammation, fibrosis, and destruction of the intrahepatic and extrahepatic bile ducts. This leads to multiple areas of stricturing in the biliary tree and eventually to cirrhosis.
Octinoxate is a chemical compound that is found in many different types of cosmetics and personal care products. Manufacturers derive this ingredient from petroleum by-products, then add it to makeup, lotion and moisturizers.unscreen products containing octinoxate may reduce freckles. Octinoxate is used in some lipsticks and other cosmetics to provide protection from the sun. Octinoxate is found in most sunscreen products. Octinoxate is made from methanol and sulfuric acid.
ZanaflexÂ® (tizanidine hydrochloride) is a central alpha2-adrenergic agonist. Tizanidine HCl is a white to off-white, fine crystalline powder, which is odorless or with a faint characteristic odor.Tizanidine is slightly soluble in water and methanol; solubility in water decreases as the pH increases.anaflexÂ® tablets contain the active ingredient, tizanidine hydrochloride (4.58 mg equivalent to 4 mg tizanidine base), and the inactive ingredients, colloidal silicon dioxide, stearic acid, microcrystalline cellulose and anhydrous lactose.