Full Definition of PERSECUTE. transitive verb. 1. : to harass or punish in a manner designed to injure, grieve, or afflict; specifically: to cause to suffer because of belief.
Note the presence of giant cells. The granulomatous lesions in this disorder are typically non-caseating. This is in constrast to TB granuloma which causes casating granuloma (slides with TB granuloma is uncommon in MRCOphth). A TB granuloma showing central necrosis (caseating granuloma) and the presence of giant cells.n addition, the macrophages may fuse together to form multinucleate giant cells (different types of inciting materials may produce different giant cells). Granulomatous lesion typically occurs when the usual acute inflammatory reaction involving neutrophils could not remove the inciting agent.
Lesion Type (Primary Morphology). Macules are flat, nonpalpable lesions usually 10 mm in diameter. Macules represent a change in color and are not raised or depressed compared to the skin surface. A patch is a large macule.laques are palpable lesions 10 mm in diameter that are elevated or depressed compared to the skin surface. Plaques may be flat topped or rounded. Lesions of psoriasis and granuloma annulare commonly form plaques. Nodules are firm papules or lesions that extend into the dermis or subcutaneous tissue.