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Bone marrow, lymph nodes, spleen, tonsils, thymus and Peyer's patches in the small intestine, the liver, and the appendix are all parts of the lymphatic system.
1 The spleen is the largest organ of the lymphatic system. 2  Its primary function is to filter blood of damaged cells, cellular debris, and pathogens. 3  Like the thymus, the spleen houses and aids in the maturation of lymphocytes. 4  Lymphocytes destroy pathogens and dead cells in the blood. Thymus. 2  The thymus gland is the main organ of the lymphatic system. 3  Its primary function is to promote the development of specific cells of the immune system called T-lymphocytes. 4  Once mature, these cells leave the thymus and are transported via blood vessels to the lymph nodes and spleen.