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Accutane side effects. Get emergency medical help if you have any of these signs of an allergic reaction to Accutane: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. joint stiffness, bone pain or fracture. cracking or peeling skin, itching, rash, changes in your fingernails or toenails.
Infection in the kidneys may also cause pain when urinating. If you have to take antibiotics for a kidney infection or UTI whilst on Accutane, make sure they are NOT tetracyclines which are contra-indicated for use with Accutane. Accutane can cause both kidney and liver problems and you should be having regular blood tests whilst on this medication. Read More.