Cause Cause. Intervertebral disc disease (IDD) is a multifactorial disorder, which means that both genetic and environmental factors probably interact to predispose an individual to the condition. It is likely that several factors are needed for development of IDD.
Osteoarthritis Flare-Ups and Management. An osteoarthritis flare-up can be quite painful and debilitating. Osteoarthritis is the most common form of arthritis, and is characterized by the degenerate of the cartilage in the joint.o help a patient with osteoarthritis deal with a flare-up, they are generally prescribed a higher dosage of an NSAID (non-steroidal anti-inflammatory drugs) medication. NSAIDs are used to treat inflammation, and can help reduce the swelling in the affected joint.
Primary osteoarthritis is mostly related to aging. With aging, the water content of the cartilage increases and the protein makeup of cartilage degenerates. Repetitive use of the joints over the years causes damage to the cartilage that leads to joint pain and swelling.rystal deposits in the cartilage can cause cartilage degeneration, and osteoarthritis. Uric acid crystals cause arthritis in gout, while calcium pyrophosphate crystals cause arthritis in pseudogout.