morphine). Since diffusion across a lipid bilayer requires that a drug be lipid-soluble, the ionized form of a drug cannot cross membranes. Thus, weak acids that are nonprotonated and weak bases that are protonated cannot diffuse across membranes. At a pH that is equal to a drugâs pKa, equal amounts of the protonated and nonprotonated forms are present. Assuming the pH is the same on both sides of a given membrane, the drug will be at equilibrium across the membrane.
Ledyba (Japanese: ã¬ãã£ã Rediba) is a Bug/Flying-type PokÃ©mon introduced in Generation II. Ledyba is a common Bug type PokÃ©mon that resembles a ladybug. It has six legs, that are all wearing gloves.
Dwebble (Japanese: ã¤ã·ãºãã¤ Ishizumai) is a Bug/Rock-type PokÃ©mon introduced in Generation V. Dwebble is a small hermit crab-like PokÃ©mon. Its body is orange, and it carries a gray rocky shell on its back. It has a round head, long eye stalks with round black eyes, and a small mouth. It has a set of four claw-like legs, with large sharp claws on its front legs.