Clonidine should not be used by people who have a known allergy to this drug. If a person has underlying depression, clonidine should be used with caution and under close physician supervision. Clonidine should not be abruptly withdrawn but rather, slowly decreased over several days to avoid withdrawal symptoms.
Three ways mutations can occur in genes are: 1. Insertion: Extra DNA nucleoties are added to the DNA strand. 2. Deletion: DNA nucleotides are deleted, therefore, changing the â¦ DNA sequence. 3. Translocation: parts of chromosomes are exchanged.or example, this can happen during crossover during the formation of gametes. Substitution mutations happen when one nucleotide (the smallest unit of DNA) is replaced by another. These are caused by a number of chemicals that look like something in between both of those nucleotides.
The two types of single gene mutations are point mutation, where a single point in the DNA sequence is affected, and FRAMESHIFT MUTATION, where a single gene or nitrogen base â¦ is deleted or added from the mRNA (messenger RNA) sequence causing a shift in the reading frame of the genetic message. gene mutation can be acquired throughout life or it is genetic ex sickle cell anemia chromsome mutations have more pronounced effects and are due to a change in the number â¦ of chromosomes or a change in the structural effect that are inherited..