This can lead to shortness of breath, as well as possible chest pain, depending on the cause of the effusion. Fever is another possible finding, but is also related to the cause of the effusion. ... Read more
Re: can benzoyl perioxide permanently damage skin??? Yes, BP can cause a dermatitis (permanent skin damage). I had problems with BP, I used it for the spots, but when I applied it my skin went red (it like burned...)on the spots I had applied the BP. I personally don't like BP at all.
1 No permanent tissue damage occurs. 2  Frostbite is freezing of the skin and the tissues under the skin because of temperatures below freezing. 3  Frostbitten skin looks pale or blue and feels cold, numb, and stiff or rubbery to the touch.