Definition and Etiology. Primary sclerosing cholangitis (PSC) is a chronic, progressive, cholestatic liver disease resulting from inflammation, fibrosis, and destruction of the intrahepatic and extrahepatic bile ducts. This leads to multiple areas of stricturing in the biliary tree and eventually to cirrhosis.
Octinoxate is a chemical compound that is found in many different types of cosmetics and personal care products. Manufacturers derive this ingredient from petroleum by-products, then add it to makeup, lotion and moisturizers.unscreen products containing octinoxate may reduce freckles. Octinoxate is used in some lipsticks and other cosmetics to provide protection from the sun. Octinoxate is found in most sunscreen products. Octinoxate is made from methanol and sulfuric acid.
RDX is the organic compound with the formula (O2NNCH2)3. It is a white solid without smell or taste, widely used as an explosive. Chemically, it is classified as a nitramide, chemically similar to HMX. A more energetic explosive than TNT, it was used widely in World War II. It is often used in mixtures with other explosives and plasticizers or phlegmatizers. RDX is stable in storage and is considered one of the most energetic and brisant of the military high explosives.