Clonidine should not be used by people who have a known allergy to this drug. If a person has underlying depression, clonidine should be used with caution and under close physician supervision. Clonidine should not be abruptly withdrawn but rather, slowly decreased over several days to avoid withdrawal symptoms.
Three ways mutations can occur in genes are: 1. Insertion: Extra DNA nucleoties are added to the DNA strand. 2. Deletion: DNA nucleotides are deleted, therefore, changing the â¦ DNA sequence. 3. Translocation: parts of chromosomes are exchanged.or example, this can happen during crossover during the formation of gametes. Substitution mutations happen when one nucleotide (the smallest unit of DNA) is replaced by another. These are caused by a number of chemicals that look like something in between both of those nucleotides.
1 Gene mutations that occur after birth. 2  Most gene mutations occur after you're born and aren't inherited. 3  A number of forces can cause gene mutations, such as smoking, radiation, viruses, cancer-causing chemicals (carcinogens), obesity, hormones, chronic inflammation and a lack of exercise.ancer is caused by changes (mutations) to the DNA within cells. The DNA inside a cell is packaged into a large number of individual genes, each of which contains a set of instructions telling the cell what functions to perform, as well as how to grow and divide.