More common. 1  Headache. 2  hoarseness. 3  lower back or side pain. 4  pain or tenderness around the eyes and cheekbones. 5  painful or difficult urination. 6  stuffy or runny nose.
trazodone oral and linezolid iv both increase affecting serotonin levels in the blood. Too much serotonin is a potentially life-threatening situation. Severe signs and symptoms include high blood pressure and increased heart rate that lead to shock.
Trazodone also may increase directly the action of serotonin. Trazodone is chemically unrelated to the selective serotonin reuptake inhibitors (SSRIs), the tricyclic antidepressants (TCAs) or the monoamine oxidase inhibitors (MAO inhibitors). It is chemically related to nefazodone (Serzone) and shares its actions.