When Shiga toxin is released from an E. coli O157:H7 bacterium, it can translocate to organs other than the digestive tract such as the kidneys and central nervous system (brain and spinal cord). This can cause hemolytic uremic syndrome (HUS) and/or thrombotic thrombocytopenic purpura (TTP) .
A strategy called dollar-cost averaging can help reduce risks surrounding an asset falling in price. The concept is straightforward - you invest a fixed amount of money in an asset once every fixed time period.
Even if one of the two criteria is met, the company should maximize observable inputs to make an estimate as illustrated in the adjusted market assessment approach and the expected cost plus margin approach. If none of these are appropriate, the residual approach can be used.