Nucleic acids are linear polymers (chains) of nucleotides. Each nucleotide consists of three components: a purine or pyrimidine nucleobase (sometimes termed nitrogenous base or simply base), a pentose sugar, and a phosphate group. The substructure consisting of a nucleobase plus sugar is termed a nucleoside.
Other studies of Remicade and methotrexate indicate that the two medications together can successfully reduce symptoms of psoriasis and psoriatic arthritis, the researchers report. Studies of Humira and Enbrel in conjunction with methotrexate also revealed the combination to be more effective than the biologic alone.
Methotrexate is a medicine that makes your immune system less active. It is used to treat certain types of cancer. It is also used to treat severe rheumatoid arthritis and psoriasis when other treatments don't help. Rheumatoid arthritis and psoriasis are autoimmune diseases, which means that they are associated with an immune system that is too active. In some cases, methotrexate can help people who have these problems.