24 yr old: transected median nerve 48 days ago at wrist level - epineural repair. Tinels sign now positive just a more 24 yr old: transected median nerve 48 days ago at wrist level - epineural repair. Tinels sign now positive just an inch below index finger.
Apoptosis (from Ancient Greek á¼ÏÏÏÏÏÏÎ¹Ï falling off) is a process of programmed cell death that occurs in multicellular organisms. Biochemical events lead to characteristic cell changes (morphology) and death. These changes include blebbing, cell shrinkage, nuclear fragmentation, chromatin condensation, chromosomal DNA fragmentation, and global mRNA decay. Between 50 and 70 billion cells die each day due to apoptosis in the average human adult.
In other words, when cancer cells become resistant to apoptosis, they become resistant to treatment, metastasize, and proliferate destructively. The concept that the malignancy of cancer is due to its resistance to apoptosis is a relatively new one and is worthy of further study.