According to the American Psychiatric Association (APA) Practice Guidelines for the Treatment of Patients with Bipolar Disorder, biochemical hypothyroidism develops in 5% to 35% of patients with bipolar disorder, usually within 6 to 18 months of lithium treatment initiation.
The longest-surviving dynasty in the world is the Imperial House of Japan, the Yamato dynasty, whose reign is traditionally dated to 660 BC.
Queen Victoria Summary. Queen Victoria was the longest-reigning British monarch, ruling the United Kingdom of Great Britain and Ireland for 64 years. She was fiercely independent and although she faced dwindling direct political control, she strengthened the monarchy by redefining its role in British life.