Usually there are other reasons for the skin changes, but we do recommend evaluation, especially if these are new, persistent or worsening. Skin changes that cause worry include: 1  Skin puckering or dimpling. 2  Nipple inversion (when nipples indent, or seem to turn inward). 3  Thickened skin tissue, with enlarged pores (known as peau d'orange, French for orange peel, which it resembles). 4  Warmth, pain or redness of the skin.
For example, a fruity breath odor is one of the characteristic symptoms of diabetic ketoacidosis, which can be fatal within hours or days. Another example is a fecal breath odor which can indicate certain types of intestinal blockage.
If you get strong perfume smell it isn't pure tobacco you are smelling. It is an added fragrance - typically an artificial. I never extracted a tobacco that smelled other than an organic woody plant. The fired cured smell like a campfire, the air dried smell very resinous, the flue cured are sweeter etc.