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Driving distance from Mobile, AL to Orlando, FL. The total driving distance from Mobile, AL to Orlando, FL is 498 miles or 801 kilometers. Your trip begins in Mobile, Alabama. It ends in Orlando, Florida. If you are planning a road trip, you might also want to calculate the total driving time from Mobile, AL to Orlando, FL so you can see when you'll arrive at your destination.
Distance to cities nearby Orlando, FL and Tampa, FL. 1  Distance from Orlando, FL to Aloma, FL. 2  Distance from Orlando, FL to Altamonte Springs, FL. 3  Distance from Orlando, FL to Alafaya, FL. 4  Distance from Orlando, FL to Apopka, FL. 5  Distance from Orlando, FL to Altoona, FL. 6  Distance from Tampa, FL to Aloma, FL.