Acne is the most common skin condition in the United States, affecting up to 50 million Americans annually. 1; Acne often causes significant physical and psychological problems such as permanent scarring, poor self-image, depression and anxiety. 2; See your dermatologist for the successful diagnosis and treatment of acne.
Mechanism of action. It is a phosphodiesterase-4 inhibitor, mainly acting on phosphodiesterase 4B (PDE4B), which causes inflammation. Chemically, crisaborole is a phenoxybenzoxaborole. It contains a boron atom that helps penetrate the skin and is essential for its binding activity.
An overview on the mechanism of action of statins: HMG CoA reductase inhibitors,or statins are widely prescribed drugs. They are indicated for the treatment of hipercholesterolemia, a condition that increases cardiovascular risk. Currently, the drugs of this group that are available are: Atorvastatin. Fluvastatin.