Structure [edit]. The gluteus maximus is the largest of the gluteal muscles and one of the strongest muscles in the human body. It inserts at the iliotibial band and the gluteal tuberosity of the femur.
Causes. Toxic megacolon occurs as a complication of inflammatory bowel disease, such as. and, and infections of the colon. The term toxic means that this complication occurs with infection or inflammation, and is very dangerous.1  ulcerative colitis.2  Crohn's disease.oxic megacolon occurs as a complication of inflammatory bowel disease, such as. and, and infections of the colon. The term toxic means that this complication occurs with infection or inflammation, and is very dangerous. 1  ulcerative colitis.
Epidemiology. 1  One study found that the most common cause of macrocytosis was medication (37%), followed by alcoholism (26%). Serum B12 and/or folate deficiency, bone marrow dysplasia and non-alcoholic liver disease each accounted for 6%. 2  The most common cause of megaloblastic anaemia is pernicious anaemia.