According to the American Psychiatric Association (APA) Practice Guidelines for the Treatment of Patients with Bipolar Disorder, biochemical hypothyroidism develops in 5% to 35% of patients with bipolar disorder, usually within 6 to 18 months of lithium treatment initiation.
The longest-surviving dynasty in the world is the Imperial House of Japan, the Yamato dynasty, whose reign is traditionally dated to 660 BC.
The Zhou Dynasty (1045â221 BC). The Zhou dynasty era lasted 800 years until the end of China's bronze age. It was the longest lasting dynasty, but the accounts say that the ruling clan slowly lost power until they became ceremonial figureheads.