The origin of irregardless is not known for certain, but the speculation among references is that it may be a blend, or portmanteau word, of the standard English words irrespective and regardless. The blend creates a word with a meaning not predictable from the meanings of its constituent morphemes.
Tramadol is a Schedule IV Controlled Substance in Ohio Effective September 1. Source: Ohio State Board of Pharmacy. Effective Monday, September 1, tramadol and products containing tramadol will be classified as Schedule IV controlled substances in the state of Ohio pursuant to Ohio Administrative Code 4729-11-03.
For those of you who may have missed it, the Drug Enforcement Administration (DEA) has officially scheduled tramadol as a Schedule IV substance within the U.S. under the Controlled Substance Act, which will be effective as of August 18 of this year. The legislation has been in the works by the DEA for over a year now.