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What layer of the skin contains melanin? The epidermis layer of the skin contains melanin producing cells, so I would assume that is the layer with melanin in it. What layer of skin produces melanin? Melanocytes, which produce melanin, are found in the basal layer of the epidermis, also called the stratum basale.
Layers of the Skin The Epidermis. The epidermis is the outermost layer of the skin, and protects the body from the environment. The thickness of the epidermis varies in different types of skin; it is only .05 mm thick on the eyelids, and is 1.5 mm thick on the palms and the soles of the feet. The epidermis contains the melanocytes (the cells in which melanoma develops), the Langerhans' cells (involved in the immune system in the skin), Merkel cells and sensory nerves.