Medulloblastomas: Medulloblastomas (PNETs) are the most common malignant brain tumor in children (20% of all pediatric tumors) and usually occur in children between the ages of 4 and 10 years. Medulloblastomas occur more often in boys than in girls.
Acanthocyte (from the Greek word á¼ÎºÎ±Î½Î¸Î± acantha, meaning 'thorn'), in human biology and medicine, refers to a form of red blood cell that has a spiked cell membrane, due to abnormal thorny projections. A similar term is spur cells.canthocytosis can be seen in: Acute or Chronic Anemia, Hepatitis A,B,C; Hepatorenal syndrome, Hypopitutarism, Malabsorption Syndromes, Malnutrition In malnourishment, such as anorexia nervosa and cystic fibrosis, acanthocytosis remits with resolution of the nutritional deficiency.
Acanthocytes are also found in myxedema, in panhypopituitarism, and in 20-65% of hypothyroidism cases. Serum lipid abnormalities with hypothyroidism are common, and patients with acanthocytes may have more severely abnormal lipids than patients with normal-shaped red cells.his image (magnified X 2000) shows the spiculated thorny RBCs (acanthocytes) as observed in an individual with abetalipoproteinemia. These are indistinguishable from the acanthocytes shown in the next image, which are observed in an individual with spur cell hemolytic anemia.