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Arava, also known by its drug name, Leflunomide, is a prescription medication approved by the Food and Drug Administration (FDA) in 1998 to treat joint pain, swelling, and stiffness associated with active rheumatoid arthritis. Arava is also prescribed for people with early-stage psoriatic arthritis. Arava is not appropriate for pregnant women, men or women who plan to conceive a pregnancy in the near future, or people with severe immunodeficiency. Arava should be used with caution by those with a history of liver problems.
Some insurance companies also require psoriasis patients to try an oral medication before starting a biologic, since biologics are far more expensive. The primary oral medications prescribed for psoriasis are methotrexate, cyclosporine, and acitretin. Heres what you should know about the different systemic medications: Methotrexate