Causes. The most common causes of megaloblastic anemia are deficiency of either cobalamin (vitamin B12) or folate (vitamin B9). These two vitamins serve as building blocks and are essential for the production of healthy cells such as the precursors to red blood cells.olate, which is also known as folic acid, is a B vitamin that is normally found in green leafy vegetables, citrus fruits, and certain grains and nuts. Folate deficiency can occur in diets that supply insufficient amounts of these foods.
While the Callery pear is popular for its attractive flowers, this tree puts on an autumn display of variegated foliage in red, purple, orange and yellow tones. The best time to prune your flowering pear is in late spring, once the flowers have passed for the year. credit: IT Stock Free/Polka Dot/Getty Images.
The best time of year to prune oak trees is from late fall until the end of March, when oak wilt disease is dormant and there is no risk of infection. If your oak tree is pruned at any other time of the year, some type of sealant should be applied to all pruning wounds to prevent oak wilt infection. Pruning paint is effective along with any latex paint. This same time period is also appropriate for trimming other species of trees, when insects and disease are dormant.