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Consequently, the incidence of VTE in the absence of. prophylaxis ranges from 40% to 60% (venographic rates) 7 to 14 days after major orthopedic surgery.1,11 The rate of. DVT during the same period is approximately 50% (Table.
Placement or removal of a spinal catheter should be delayed for at least 12 hr after administration of prophylactic doses (eg, doses used for DVT prevention) Longer delays (24 hr) are appropriate to consider for patients receiving higher therapeutic doses (eg, enoxaparin 1 mg/kg BID or 1.5 mg/kg qDay)