Nucleic acids are linear polymers (chains) of nucleotides. Each nucleotide consists of three components: a purine or pyrimidine nucleobase (sometimes termed nitrogenous base or simply base), a pentose sugar, and a phosphate group. The substructure consisting of a nucleobase plus sugar is termed a nucleoside.
Other studies of Remicade and methotrexate indicate that the two medications together can successfully reduce symptoms of psoriasis and psoriatic arthritis, the researchers report. Studies of Humira and Enbrel in conjunction with methotrexate also revealed the combination to be more effective than the biologic alone.
1 Methotrexate is one of the most commonly used drugs in the treatment of rheumatoid arthritis. 2  It helps with pain and swelling and also slows the progression of arthritis over time.3  Methotrexate requires careful monitoring to reduce risk of liver injury and infections. Methotrexate is one of the most commonly used drugs in the treatment of rheumatoid arthritis. 2  It helps with pain and swelling and also slows the progression of arthritis over time.