Protein phosphorylation is a reversible post-translational modification of proteins. In eukaryotes, protein phosphorylation functions in cell signaling, gene expression, and differentiation. It is also involved in DNA replication during the cell cycle, and the mechanisms that cope with stress-induced replication blocks.
Cake Doughnut. A single glazed chocolate cake doughnut that is around 3 3/4 inches in diameter can have close to 250 calories. Depending on the recipe, some varieties -- like chocolate-frosted chocolate cake doughnuts -- can have as many as 370 calories.
They may all be high in sugar and fat, but some Krispy Kreme varieties differ hugely when you're counting calories. For example, a glazed original doughnut will cost you just over 200 calories and 13g of fat, while a chocolate-iced and cream-filled version will set you back a whopping 339 calories and 15g of fat. At almost one fifth of an average woman's recommended daily calorie intake, you'd have to really want that one.