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Best Answer: a normal head of lettuce can weigh between 10oz, and 1 1/2 lbs. I should know I am addicted to lettuce. I eat it every single day. If you put three largish leaves, in your sandwhich the calorie content is small. A 1lb head of lettuce will have around 60 calories. So each leaf is around 5 calories. That is a normal sliced loaf size of bread. If it's a foot long, say at Subway, type thing, you have more lettuce- about five or sixe leaves, but they will be smaller leaves, so at most 30 calories.
For leaf lettuce, start picking the leaves when there is at least 5-6 mature leaves of usable size. Usable size means about 2 long for baby lettuce, and 5-6 long for more mature lettuce. Keep picking until a seed stalk appears or the leaves become bitter.