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1 Gonorrhea and chlamydia are the most common causes of epididymitis in young, sexually active men. 2  Other infections. 3  For boys and men who aren't sexually active, epididymitis can be caused by a nonsexually transmitted bacterial infection.
Epididymitis is one such health issue that affects the male reproductive organs. Epididymitis involves the inflammation of the epididymis, or the coiled tube located at the back of the testicle that functions to store and carry sperm. The inflammation associated with epididymitis also causes pain and additional swelling of the region.