According to the American Psychiatric Association (APA) Practice Guidelines for the Treatment of Patients with Bipolar Disorder, biochemical hypothyroidism develops in 5% to 35% of patients with bipolar disorder, usually within 6 to 18 months of lithium treatment initiation.
The longest-surviving dynasty in the world is the Imperial House of Japan, the Yamato dynasty, whose reign is traditionally dated to 660 BC.
Her 62 years on the throne still leave her some way short of being the worldâs longest-reigning current monarch. That distinction goes to Thailandâs king, Bhumibol Adulyadej, who will celebrate 69 years on the throne in June. He was just 18 when he became king.