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What layer of the skin contains melanin? The epidermis layer of the skin contains melanin producing cells, so I would assume that is the layer with melanin in it. What layer of skin produces melanin? Melanocytes, which produce melanin, are found in the basal layer of the epidermis, also called the stratum basale.
In addition to the keratinocyte, other cells in the epidermis can be observed: 4 Layers and cell types of the epidermis. -Melanocytes: These cells are responsible for the synthesis of melanin, which is responsible for the coloration of the skin.