24 yr old: transected median nerve 48 days ago at wrist level - epineural repair. Tinels sign now positive just a more 24 yr old: transected median nerve 48 days ago at wrist level - epineural repair. Tinels sign now positive just an inch below index finger.
Apoptosis (from Ancient Greek á¼ÏÏÏÏÏÏÎ¹Ï falling off) is a process of programmed cell death that occurs in multicellular organisms. Biochemical events lead to characteristic cell changes (morphology) and death. These changes include blebbing, cell shrinkage, nuclear fragmentation, chromatin condensation, chromosomal DNA fragmentation, and global mRNA decay. Between 50 and 70 billion cells die each day due to apoptosis in the average human adult.
For example, Fos63, Myc64 and Nur772are transcription factors that have been implicated in some forms of apoptosis and in growth factor signal transduction pathways. Additionally, the tumour suppressor protein p53 can promote apoptosis6s, and it is known that p53 is a phospho- protein.