Bearing in mind that HIF-1 is essential for heat acclimation, we tested whether this pathway contributes to the cross-tolerance phenomenon as well. Our findings from this investigation confirmed that heat acclimation induces cross-tolerance to heavy metals (cadmium) and chemical hypoxia in the wild-type C. elegans.
Mic was founded in 2011 by Chris Altchek and Jake Horowitz. We are headquartered in New York with teams in San Francisco, Los Angeles, Chicago, Toronto, Kiev, Stockholm and Berlin. We are a venture-backed company on a mission to inform, empower and inspire our audience.
There is a tiny hole on the edge for the mic, and another hole nearby, on the rear, for noise-canceling. You can test the microphone clarity by making two recordings. Speak into the edge where the mic is located, and speak into the opposite edge. The first recording will be very slightly clearer.