The Cavitron Ultrasonic Surgical Aspirator is a unique modality for precise tissue removal which results in increased visibility, reduced bleeding, and shorter operating time when dealing with vascular lesions or organs.
The SOD1 mouse develops an ALS-like disease that researchers hope overlaps enough with human ALS that mouse responses to treatment might predict human responses. SOD1 gene mutations, however, cause a familial (inherited) form of human ALS thatâs present in only 1 percent to 3 percent of ALS cases. For some 90 percent of patients, the disease isnât familial. Its onset is unpredictable (sporadic) and the cause is unknown.
By analyzing brain tissue from patients with ALS or FTD, Dr. Petrucelli and his team discovered that the abnormal protein, which they call C9RANT, is generated as a result of repeat expansions of nucleotides in the noncoding region of the C9ORF72 gene. These expansions are the most common cause of ALS and FTD.