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Definition of computation. 1  1a : the act or action of computing : calculationb : the use or operation of a computer. 2  2 : a system of reckoning. 3  3 : an amount computed.
Computational neuroscience is the study of brain function in terms of the information processing properties of the structures that make up the nervous system. It is an interdisciplinary science that links the diverse fields of neuroscience, cognitive science and psychology with electrical engineering, computer science, mathematics and physics.