According to the American Psychiatric Association (APA) Practice Guidelines for the Treatment of Patients with Bipolar Disorder, biochemical hypothyroidism develops in 5% to 35% of patients with bipolar disorder, usually within 6 to 18 months of lithium treatment initiation.
The longest-surviving dynasty in the world is the Imperial House of Japan, the Yamato dynasty, whose reign is traditionally dated to 660 BC.
Queen Victoria is the longest reigning monarch in UK history. Queen Victoria was only 18 when she came to the throne and she had a lot to learn. Her reign had a rocky start.She thought that, as queen, she could do as she liked, and she quickly had to learn that she couldn't. Queen Victoria's reign spanned sixty four years, from 1837 - 1901.ueen Victoria is the longest reigning monarch in UK history. Queen Victoria was only 18 when she came to the throne and she had a lot to learn. Her reign had a rocky start.