Introduction. Facets is a web application framework that leverages a simple MVC architecture for the server side and a feature-packed Javascript component model for the client. The two pieces are designed to be seemlessly integrated for very dynamic AJAX-style apps.
Histotoxic hypoxia refers to a reduction in ATP production by the mitochondria due to a defect in the cellular usage of oxygen. An example of histotoxic hypoxia is cyanide poisoning.
The main symptoms of acute poisoning by cyanides are due to the interference of cyanide in the assimilation and distribution of oxygen in the body. Whether the cyanide source is HCN or ingestion of food containing a water soluble cyanide such as potassium or sodium salt, the poisoning mechanism is the same.The cyanide ions react irreversibly with the iron, in particular with the iron in the cytochrome c oxidase and hemoglobin.hether the cyanide source is HCN or ingestion of food containing a water soluble cyanide such as potassium or sodium salt, the poisoning mechanism is the same. The cyanide ions react irreversibly with the iron, in particular with the iron in the cytochrome c oxidase and hemoglobin.