The origin of irregardless is not known for certain, but the speculation among references is that it may be a blend, or portmanteau word, of the standard English words irrespective and regardless. The blend creates a word with a meaning not predictable from the meanings of its constituent morphemes.
Tramadol is a Schedule IV Controlled Substance in Ohio Effective September 1. Source: Ohio State Board of Pharmacy. Effective Monday, September 1, tramadol and products containing tramadol will be classified as Schedule IV controlled substances in the state of Ohio pursuant to Ohio Administrative Code 4729-11-03.
Hence, it is classified as a controlled substance in many countries. Internationally, phentermine is a schedule IV drug under the Convention on Psychotropic Substances. In the United States, it is classified as a Schedule IV controlled substance under the Controlled Substances Act. Phentermine, like many other prescription drugs, works with neurotransmitters in the brain.