A GSM modem can be an external device or a PC Card / PCMCIA Card. Typically, an external GSM modem is connected to a computer through a serial cable or a USB cable. A GSM modem in the form of a PC Card / PCMCIA Card is designed for use with a laptop computer.
Entresto is supplied as a tablet for oral administration. The recommended starting dose of Entresto is 49/51 mg (sacubitril/valsartan) twice-daily. Double the dose of Entresto after 2 to 4 weeks to the target maintenance dose of 97/103 mg (sacubitril/valsartan) twice-daily, as tolerated by the patient.
Avoid use of ENTRESTO with an ARB, because ENTRESTO contains the angiotensin II receptor blocker valsartan. The concomitant use of ENTRESTO with aliskiren is contraindicated in patients with diabetes [see Contraindications. (4)]. Avoid use with aliskiren in patients with renal impairment (eGFR <60 mL/min/1.73 mÂ²).