Acne is the most common skin condition in the United States, affecting up to 50 million Americans annually. 1; Acne often causes significant physical and psychological problems such as permanent scarring, poor self-image, depression and anxiety. 2; See your dermatologist for the successful diagnosis and treatment of acne.
Mechanism of action. It is a phosphodiesterase-4 inhibitor, mainly acting on phosphodiesterase 4B (PDE4B), which causes inflammation. Chemically, crisaborole is a phenoxybenzoxaborole. It contains a boron atom that helps penetrate the skin and is essential for its binding activity.
Last reviewed on RxList 7/10/2015. Pradaxa (dabigatran) is an anticoagulant that works by blocking the clotting protein thrombin. Pradaxa is used to prevent blood clots from forming because of a certain irregular heart rhythm (atrial fibrillation). Preventing these blood clots helps to reduce the risk of a stroke.ide effects of Pradaxa include bruising and minor bleeding, nausea, abdominal or stomach pain, stomach upset, indigestion, heartburn, nausea, diarrhea, skin rash, or itching. The usual recommended dose of Pradaxa is 150 mg taken orally, twice daily Pradaxa is administered in capsule form.