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Hedgehog signaling pathway. The Hedgehog signaling pathway is a signaling pathway that transmits information to embryonic cells required for proper cell differentiation. Different parts of the embryo have different concentrations of hedgehog signaling proteins. The pathway also has roles in the adult. Diseases associated with the malfunction of this pathway include basal cell carcinoma. The Hedgehog signaling pathway is one of the key regulators of animal development and is present in all bilaterians. The pathway takes its
At the time when the Hedgehog gene was isolated from vertebrates, Sonic the Hedgehog videogame was popular as I suppose one of the post docs that cloned it had a kid that liked to play Sonic the Hedgehog so that's how Sonic was given its name.n a normal embryo, the patterning of the nervous system happens on a temporal scale from head to tail basically, and it's almost like a zipper being closed. Hedgehog signaling is coming from the notochord to the overlying neurectoderm pattern: the head, then the trunk, then the tail, and so on.