According to the American Psychiatric Association (APA) Practice Guidelines for the Treatment of Patients with Bipolar Disorder, biochemical hypothyroidism develops in 5% to 35% of patients with bipolar disorder, usually within 6 to 18 months of lithium treatment initiation.
The longest-surviving dynasty in the world is the Imperial House of Japan, the Yamato dynasty, whose reign is traditionally dated to 660 BC.
However, the world's longest-reigning monarch is the king of Thailand, who marked the 69th year of his reign in June. Britain's monarch is nonetheless the world's eldest, after Saudi king Abdullah died in January at the age of 90. Following is a list of the current longest-reigning heads of state: