Nucleic acids are linear polymers (chains) of nucleotides. Each nucleotide consists of three components: a purine or pyrimidine nucleobase (sometimes termed nitrogenous base or simply base), a pentose sugar, and a phosphate group. The substructure consisting of a nucleobase plus sugar is termed a nucleoside.
Other studies of Remicade and methotrexate indicate that the two medications together can successfully reduce symptoms of psoriasis and psoriatic arthritis, the researchers report. Studies of Humira and Enbrel in conjunction with methotrexate also revealed the combination to be more effective than the biologic alone.
Do not use methotrexate to treat psoriasis or rheumatoid arthritis if you have: alcoholism, cirrhosis, or other liver disease; a blood cell disorder such as anemia (lack of red blood cells) or leukopenia (lack of white blood cells); a bone marrow disorder; or. if you are breast-feeding a baby.