Full Definition of PERSECUTE. transitive verb. 1. : to harass or punish in a manner designed to injure, grieve, or afflict; specifically: to cause to suffer because of belief.
Note the presence of giant cells. The granulomatous lesions in this disorder are typically non-caseating. This is in constrast to TB granuloma which causes casating granuloma (slides with TB granuloma is uncommon in MRCOphth). A TB granuloma showing central necrosis (caseating granuloma) and the presence of giant cells.n addition, the macrophages may fuse together to form multinucleate giant cells (different types of inciting materials may produce different giant cells). Granulomatous lesion typically occurs when the usual acute inflammatory reaction involving neutrophils could not remove the inciting agent.
Best Answer: Toxic granulation refers to changes in granulocyte cells seen on examination of the peripheral blood film of patients with inflammatory conditions. They are commonly found in patients with sepsis. Toxic granulations are dark coarse granules found in granulocytes, particularly neutrophils. Along with Dohle bodies and cytosolic vacuolation, which are two other findings in the cytoplasm of granulocytes, toxic granulations are a peripheral blood film finding suggestive of an inflammatory process. http://en.wikipedia.org/wiki/Toxic_granu...