Granulomatosis with polyangiitis (formerly known as Wegener granulomatosis) is characterized by necrotizing granulomatous inflammation, small- and medium-sized vessel vasculitis, and focal necrotizing glomerulonephritis, often with crescent formation.
Brand name: Coumadin. Side effects are often related to abnormal bleeding. These include bruising easily, nosebleeds, bleeding from your gums, bleeding from cuts that takes a long time to stop, and heavier than normal menstrual bleeding. Warfarin is used to treat and prevent blood clots that might result in heart attack, stroke, or death.
As mentioned earlier, warfarin works by preventing the recycling of vitamin K, diminishing levels of the vitamin available to the body, and contributing to weaker bones and increased fractures. 23 This problem is compounded by the fact that many of the people using warfarin are elderly and already have osteoporosis and compromised bone integrity.