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What layer of the skin contains melanin? The epidermis layer of the skin contains melanin producing cells, so I would assume that is the layer with melanin in it. What layer of skin produces melanin? Melanocytes, which produce melanin, are found in the basal layer of the epidermis, also called the stratum basale.
Melanin is found in several areas of the human body including: 1  Skin where it provides skin color. 2  Hair. 3  Pupils or irises of the eyes. 4  Stria vascularis of the inner ear. 5  Areas of the brain, the substantia nigra and locus coeruleus. 6  The medulla and zona reticularis of the adrenal gland.