Origin. Macrophages come from specific white blood cells called monocytes. Monocytes are born from stem cells in the bone marrow and circulate throughout the blood stream. Once a monocyte leaves the blood, it matures into a wandering macrophage or a fixed macrophage. Wandering macrophages travel throughout both blood and lymph streams to perform their job; fixed macrophages strategically concentrate in specific areas that are more vulnerable to intruders like the lungs or the intestine.
At-large is a designation for members of a governing body who are elected or appointed to represent the whole membership of the body, rather than a subset of that membership. At-large voting is in contrast to voting by electoral districts. If an at-large election is called to choose a single candidate, a single-winner voting system must necessarily be used. If a group of seats must be covered, many electoral systems can be possible, from proportional representation methods to block voting.
Faction definition, a group or clique within a larger group, party, government, organization, or the like: a faction in favor of big business. See more. Dictionary.com