According to the American Psychiatric Association (APA) Practice Guidelines for the Treatment of Patients with Bipolar Disorder, biochemical hypothyroidism develops in 5% to 35% of patients with bipolar disorder, usually within 6 to 18 months of lithium treatment initiation.
The longest-surviving dynasty in the world is the Imperial House of Japan, the Yamato dynasty, whose reign is traditionally dated to 660 BC.
Queen Elizabeth II of the United Kingdom â 64 years. Queen Elizabeth II ascended to the British throne in 1952 following the death of her father George VI, making her the longest-reigning monarch in the world. Last year, the 90-year-old surpassed the reign of her great-great-grandmother, Queen Victoria, which lasted from 1837 to 1901.