The origin of irregardless is not known for certain, but the speculation among references is that it may be a blend, or portmanteau word, of the standard English words irrespective and regardless. The blend creates a word with a meaning not predictable from the meanings of its constituent morphemes.
Tramadol is a Schedule IV Controlled Substance in Ohio Effective September 1. Source: Ohio State Board of Pharmacy. Effective Monday, September 1, tramadol and products containing tramadol will be classified as Schedule IV controlled substances in the state of Ohio pursuant to Ohio Administrative Code 4729-11-03.
In addition, while not the primary reason for taking Tramadol, it has also been successfully used for mild cases of depression. Keep in mind that Tramadol is not a controlled substance like many other medications prescribed for pain today to include Demerol, oxycodone, morphine, methadone, and hydrocodone. That means in the United States, it is not under control of the Federal government.