Acne is the most common skin condition in the United States, affecting up to 50 million Americans annually. 1; Acne often causes significant physical and psychological problems such as permanent scarring, poor self-image, depression and anxiety. 2; See your dermatologist for the successful diagnosis and treatment of acne.
Mechanism of action. It is a phosphodiesterase-4 inhibitor, mainly acting on phosphodiesterase 4B (PDE4B), which causes inflammation. Chemically, crisaborole is a phenoxybenzoxaborole. It contains a boron atom that helps penetrate the skin and is essential for its binding activity.
For Patients. Effient (prasugrel) is an antiplatelet drug that prevents the platelets in the bloodstream from aggregating and forming blood clots, used to prevent blood clots in people with acute coronary syndrome who are undergoing a procedure after a recent heart attack or stroke, and in people with certain disorders of the heart or blood vessels.