Clonidine should not be used by people who have a known allergy to this drug. If a person has underlying depression, clonidine should be used with caution and under close physician supervision. Clonidine should not be abruptly withdrawn but rather, slowly decreased over several days to avoid withdrawal symptoms.
Three ways mutations can occur in genes are: 1. Insertion: Extra DNA nucleoties are added to the DNA strand. 2. Deletion: DNA nucleotides are deleted, therefore, changing the â¦ DNA sequence. 3. Translocation: parts of chromosomes are exchanged.or example, this can happen during crossover during the formation of gametes. Substitution mutations happen when one nucleotide (the smallest unit of DNA) is replaced by another. These are caused by a number of chemicals that look like something in between both of those nucleotides.
Gene mutation is basically the change in the nucleotide sequence while chromosome mutation is the change in several genes. These gene mutations are basically small changes in the gene while chromosome mutation is the alteration that happens on a large scale.. Gene mutation. Gene mutation is considered as the small scale change in a nucleotide sequence. The altering of the genetic material on an organism happens in two ways. Point mutations and frame shift mutations are two bases which play a vital role whenever any change happens in a nucleotide sequence.