According to the American Psychiatric Association (APA) Practice Guidelines for the Treatment of Patients with Bipolar Disorder, biochemical hypothyroidism develops in 5% to 35% of patients with bipolar disorder, usually within 6 to 18 months of lithium treatment initiation.
The longest-surviving dynasty in the world is the Imperial House of Japan, the Yamato dynasty, whose reign is traditionally dated to 660 BC.
King Bhumibol Adulyadej of Thailand, on the throne for 68 years, is the current longest reigning monarch. Top 10 oldest monarchs in the world, including heads of states within countries. Queen Elizabeth II will overtake Queen Victoria as the longest reigning British monarch in September. King of Malaysia, Abdul Halim.