Origin. Macrophages come from specific white blood cells called monocytes. Monocytes are born from stem cells in the bone marrow and circulate throughout the blood stream. Once a monocyte leaves the blood, it matures into a wandering macrophage or a fixed macrophage. Wandering macrophages travel throughout both blood and lymph streams to perform their job; fixed macrophages strategically concentrate in specific areas that are more vulnerable to intruders like the lungs or the intestine.
At-large is a designation for members of a governing body who are elected or appointed to represent the whole membership of the body, rather than a subset of that membership. At-large voting is in contrast to voting by electoral districts. If an at-large election is called to choose a single candidate, a single-winner voting system must necessarily be used. If a group of seats must be covered, many electoral systems can be possible, from proportional representation methods to block voting.
25 National Convention At-Large delegates are elected by the convention as a whole. The 3 party leaders, the National Committeeman, the National Committeewoman, and the chairman of the Louisiana's Republican Party, will attend the convention as unpledged delegates by virtue of their position.Delegates to the National Convention ... are bound ... on the first ballot only ....5 National Convention At-Large delegates are elected by the convention as a whole. The 3 party leaders, the National Committeeman, the National Committeewoman, and the chairman of the Louisiana's Republican Party, will attend the convention as unpledged delegates by virtue of their position.