Gabapentin enacarbil extended release tablets are available under the trade name HORIZANT (R): -The recommended dosage is 600 mg orally 2 times a day. Therapy should be initiated at a dose of 600 mg orally in the morning for 3 days of therapy, then increased to 600 mg 2 times a day (1200 mg/day) on day four.
Philadelphia's central city was created in the 17th century following the plan by William Penn's surveyor Thomas Holme.
Philadelphia County is one of the three original counties, along with Chester and Bucks counties, created by William Penn in November 1682. Since 1854, the county has been coterminous with the city of Philadelphia, which also serves as its seat.