morphine). Since diffusion across a lipid bilayer requires that a drug be lipid-soluble, the ionized form of a drug cannot cross membranes. Thus, weak acids that are nonprotonated and weak bases that are protonated cannot diffuse across membranes. At a pH that is equal to a drugâs pKa, equal amounts of the protonated and nonprotonated forms are present. Assuming the pH is the same on both sides of a given membrane, the drug will be at equilibrium across the membrane.
Ledyba (Japanese: ã¬ãã£ã Rediba) is a Bug/Flying-type PokÃ©mon introduced in Generation II. Ledyba is a common Bug type PokÃ©mon that resembles a ladybug. It has six legs, that are all wearing gloves.
Trivia. 1  Feebas has similarities to Magikarp. Both are known as the Fish PokÃ©mon, both know the same level up moves, both have the same stats, and both evolve into a serpentine PokÃ©mon. 2  Feebas is the first and only PokÃ©mon so far to change its method of evolution from one generation to another.