Quoted from the NIH: Normally, the immune system helps protect the body, but with Crohn's disease the immune system can't tell the difference between normal body tissue and foreign substances. The result is an overactive immune response that leads to chronic inflammation. I have never heard someone say Crohn's isn't an autoimmune disease.
For the neonate with FMAIT, platelet transfusion is the treatment of choice and should be given to normalise the platelet count in an infant with ICH or to treat severe throbmobocytopaenia in infants without ICH. Platelets used for neonates with FMAIT should be negative for the implicated platelet-specific antigen.
Bacterial contamination of blood products, especially in platelets that are stored at room temperature, is the most common infectious risk of blood transfusion, occurring in approximately 1 of 2000-3000 platelet transfusions. Transfusionâtransmitted sepsis, while less common, can cause severe illness and death. wide variety of organisms, including bacteria, viruses, prions, and parasites can be transmitted through blood transfusions. The use of a standard donor screening questionnaire as well as laboratory tests help to reduce the risk of an infectious organism being transmitted by blood transfusion.