Full Definition of PERSECUTE. transitive verb. 1. : to harass or punish in a manner designed to injure, grieve, or afflict; specifically: to cause to suffer because of belief.
Note the presence of giant cells. The granulomatous lesions in this disorder are typically non-caseating. This is in constrast to TB granuloma which causes casating granuloma (slides with TB granuloma is uncommon in MRCOphth). A TB granuloma showing central necrosis (caseating granuloma) and the presence of giant cells.n addition, the macrophages may fuse together to form multinucleate giant cells (different types of inciting materials may produce different giant cells). Granulomatous lesion typically occurs when the usual acute inflammatory reaction involving neutrophils could not remove the inciting agent.
A solitary pulmonary nodule, or âcoin lesion,â is an approximately round lesion that is less than 3 cm in diameter and that is completely surrounded by pulmonary parenchyma, without other abnormalities. Lesions larger than 3 cm are called masses and are often malignant.