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What layer of the skin contains melanin? The epidermis layer of the skin contains melanin producing cells, so I would assume that is the layer with melanin in it. What layer of skin produces melanin? Melanocytes, which produce melanin, are found in the basal layer of the epidermis, also called the stratum basale.
Melanocytes produce melanin. Keratinocytes are old and stuck together by lots of desmosomes. Langerhans cells part of the immune system, protects micros. Merkel cells the least amount of cells located in the deepest layer of epidermas, acts as a sensory receptor.