Nucleic acids are linear polymers (chains) of nucleotides. Each nucleotide consists of three components: a purine or pyrimidine nucleobase (sometimes termed nitrogenous base or simply base), a pentose sugar, and a phosphate group. The substructure consisting of a nucleobase plus sugar is termed a nucleoside.
Other studies of Remicade and methotrexate indicate that the two medications together can successfully reduce symptoms of psoriasis and psoriatic arthritis, the researchers report. Studies of Humira and Enbrel in conjunction with methotrexate also revealed the combination to be more effective than the biologic alone.
1 Methotrexate is a medication which is used to treat cancer and rheumatoid arthritis. 2  It has powerful side effects, including the creation of secondary osteoporosis. 3  Lithium, thyroxine, some hormonal drugs, tacrolimus, and cyclosporine A increase the risk of secondary osteoporosis.