During relaxation of the heart (diastole) the left ventricle of the heart fills with blood returning from the lungs. The left ventricle then contracts and pumps blood into the arteries (systole). The blood pressure in the arteries during contraction of the ventricle (systolic pressure) is higher because blood is being actively ejected into the arteries. It is lower during relaxation of the ventricle (diastolic pressure) when no blood is being ejected into the arteries.
The Premarin family of drugs contains estrogenic compounds that are made from the urine of pregnant mares. Thatâs where the name is derived from: PRE gnant MA resâ ur IN e = Premarin. Any HRT with Prem in the brand name is likely to contain conjugated equine (o)estrogen (CEE).
Interestingly, progesterone is made in your body from cholesterol and the progesterone your body produces has an identical molecular structure to the compounded natural bioidentical progesterone. First, your body turns cholesterol into pregnenolone. The Pregnenolone is then converted into progesterone and then your body then makes a cascade of other hormones that it needs from progesterone. Progesterone serves as a precursor not only to DHEA, testosterone and estrogen, but also to cortisol, the stress hormone. It is also the precursor to the sex hormones estrogen and testosterone and is secreted primarily by the ovaries in females and by the testes in men.