Introduction. The Renaissance refers to the era in Europe from the 14th to the 16th century in which a new style in painting, sculpture and architecture developed after the Gothic.
Sickle cell disease is caused by a genetic abnormality in the gene for hemoglobin, which results in the production of sickle hemoglobin. When oxygen is released from sickle hemoglobin, it sticks together and forms long rods, which damage and change the shape of the red blood cell.eople who inherit only one sickle hemoglobin gene are carriers (sickle cell trait) and do not have anemia or painful sickle cell crises. They may, though, have a slightly higher incidence of certain conditions such as blood in the urine or urinary tract infections. About 2 million Americans have sickle cell trait.
Children with sickle cell disease have two defective hemoglobin S genes, one from each parent. Various forms of sickle cell disorder occur when a person inherits one hemoglobin S gene (sickle cell gene) from one parent and one other type of defective hemoglobin gene from the other parent.hildren with sickle cell disease have two defective hemoglobin S genes, one from each parent. Various forms of sickle cell disorder occur when a person inherits one hemoglobin S gene (sickle cell gene) from one parent and one other type of defective hemoglobin gene from the other parent.