Another possibility that can explain the pain is pericarditis. It causes chest pain aggravated by laughing yawning and deep breathing and also causes radiation of pain to arms. Again an EKG, heat echo and chest X-ray is required. I think you should discuss these possibilities with your doctor.
This is due to the confering of such atypia to progeny-cells further down the lineage of that cell type. The term atypia is also used dermatologically and can be a precursor to melanoma. The related concept of dysplasia refers to an abnormality of development, and includes abnormalities on larger, histopathologic, scales.
What is Kniest dysplasia? Kniest dysplasia: A rare genetic bone growth disorder characterized by dwarfism, enlarged joints and facial deformities. Kniest dysplasia is listed as a rare disease by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Kniest dysplasia, or a subtype of Kniest dysplasia, affects less than 200,000 people in the US population.