Freebase(0.00 / 0 votes)Rate this definition: Japan is an island nation in East Asia. Located in the Pacific Ocean, it lies to the east of the Sea of Japan, China, North Korea, South Korea and Russia, stretching from the Sea of Okhotsk in the north to the East China Sea and Taiwan in the south.
Signs and symptoms of neuroendocrine cancer. A sign is something that can be observed and recognized by a doctor or healthcare professional (for example, a rash). A symptom is something that only the person experiencing it can feel and know (for example, pain or tiredness).
The signs and symptoms of a brain tumor vary greatly and depend on the brain tumor's size, location and rate of growth. General signs and symptoms caused by brain tumors may include: 1  New onset or change in pattern of headaches. 2  Headaches that gradually become more frequent and more severe.3  Unexplained nausea or vomiting. 4  Vision problems, such as blurred vision, double vision or loss of peripheral vision.he signs and symptoms of a brain tumor vary greatly and depend on the brain tumor's size, location and rate of growth. General signs and symptoms caused by brain tumors may include: 1  New onset or change in pattern of headaches. 2  Headaches that gradually become more frequent and more severe.