Binding of PPARÎ³ to coactivators appears to reduce the levels of coactivators available for binding to pro-inflammatory transcription factors such as NF-ÎºB; this causes a decrease in transcription of a number of pro inflammatory genes, including various interleukins and tumour necrosis factors.
Email. Print. The medial collateral ligament (MCL) is a wide, thick band of tissue that runs down the inner part of the knee from the thighbone (femur) to a point on the shinbone (tibia) about four to six inches from the knee.
Where is your LCL? The LCL ligament is found along the outside of the knee and connects the femur to the smaller bone of the leg bone (fibula). The LCL along with the MCL are both collateral ligaments meaning they are found along the sides of the knee. The LCL controls the side to side movement within the knee. Since the LCL does not connect to the meniscus or knee joint capsule, it is more flexible, and less vulnerable to knee injuries. An LCL injury is however very common in contact sports such as football and soccer.