What is the definition of a dominant trait in biology? What is the difference between biology and AP biology? What is the difference between molecular biology and cell biology?
DNA gyrase, often referred to simply as gyrase, is an enzyme that relieves strain while double-strand DNA is being unwound by helicase. It is also known as DNA topoisomerase II. This causes negative supercoiling of the DNA. Bacterial DNA gyrase is the target of many antibiotics, including nalidixic acid, novobiocin, and ciprofloxacin.
32 â¢ The chromosomal DNA in bacteria is negatively supercoiledâIn E. coli, there is one negative supercoil per 40 turns of the double helixâ¢ Negative supercoiling has two major effectsâ 1. Helps in the compaction of the chromosomeâ 2.