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The list of signs and symptoms mentioned in various sources for Hemoglobin SC includes the 15 symptoms listed below: 1  Proliferative retinopathy. 2  Sudden weakness. 3  Severe joint pain.  Pain in 1  extremities. Abdominal cramps. 2  Fever. Spontaneous blood in the 3  urine. Nosebleed.  Neurological 1  manifestations. 2  Headache. Drowsiness.
These hemoglobinopathies are inherited single gene disorders. Hemoglobinopathies affect the red blood cells' ability to carry oxygen from the lungs to other parts of the body. An example of hemoglobin disease is sickle cell anemia.