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autoimmune disease, one of a large group of diseases characterized by altered function of the immune system of the body, resulting in the production of antibodies against the body's own cells.ome autoimmune disorders, such as Hashimoto's disease, are tissue specific, whereas others, such as SLE, affect multiple organs and systems. Both genetic and environmental triggers may contribute to autoimmune disease. About 5-8% of the U.S. population is affected by an autoimmune disease.
Lupus is an autoimmune disease characterized by inflammation of different tissues of the body. Autoimmune diseases happen when the bodyâs immune system attacks its own tissues.The most common type of lupus is systemic lupus erythematosus (SLE), which affects different parts of the body including internal organs.LE is an autoimmune disease in which the immune system makes antibodies to cells in the body leading to widespread inflammation and tissue damage. For an epidemiologic overview of SLE, visit the CDC Arthritis Program's lupus page.