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The list of signs and symptoms mentioned in various sources for Hemoglobin SC includes the 15 symptoms listed below: 1  Proliferative retinopathy. 2  Sudden weakness. 3  Severe joint pain.  Pain in 1  extremities. Abdominal cramps. 2  Fever. Spontaneous blood in the 3  urine. Nosebleed.  Neurological 1  manifestations. 2  Headache. Drowsiness.
Blood disorders can cause various symptoms in almost any area of the body. Most commonly, symptoms are caused by decreases in the blood components. Decreased red blood cells and hemoglobin can cause symptoms of anemia, such as fatigue, weakness, and shortness of breath (see Overview of Anemia). Decreased white blood cells or immune system proteins can cause recurrent fever and infections (see Fever in Adults).