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The list of signs and symptoms mentioned in various sources for Hemoglobin SC includes the 15 symptoms listed below: 1  Proliferative retinopathy. 2  Sudden weakness. 3  Severe joint pain.  Pain in 1  extremities. Abdominal cramps. 2  Fever. Spontaneous blood in the 3  urine. Nosebleed.  Neurological 1  manifestations. 2  Headache. Drowsiness.
BACKGROUND: Methemoglobinemia is a rare, but serious condition in which the amount of oxygen carried through the blood stream is greatly reduced. In the most severe cases, methemoglobinemia can result in death. Patients who develop methemoglobinemia may experience signs and symptoms such as pale, gray or blue colored skin, lips, and nail beds; headache ; lightheadedness; shortness of breath; fatigue; and rapid heart rate.