Freebase(0.00 / 0 votes)Rate this definition: Japan is an island nation in East Asia. Located in the Pacific Ocean, it lies to the east of the Sea of Japan, China, North Korea, South Korea and Russia, stretching from the Sea of Okhotsk in the north to the East China Sea and Taiwan in the south.
Signs and symptoms of neuroendocrine cancer. A sign is something that can be observed and recognized by a doctor or healthcare professional (for example, a rash). A symptom is something that only the person experiencing it can feel and know (for example, pain or tiredness).
Signs and symptoms of uterine cancer are: 1  unusual vaginal bleeding. 2  bleeding that starts after menopause. 3  bleeding between periods in premenopausal women. 4  heavy frequent bleeding before or during menopause. 5  bleeding with intercourse. 6  unusual vaginal discharge. 7  foul smelling.8  pus-like.ate signs and symptoms. Late signs and symptoms occur as the cancer grows larger or spreads to other parts of the body, including other organs. 1  pain. 2  lower abdomen. 3  pelvis. 4  back. 5  legs. 6  change in bladder habits. 7  pain during urination. 8  difficult urination.