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The list of signs and symptoms mentioned in various sources for Hemoglobin SC includes the 15 symptoms listed below: 1  Proliferative retinopathy. 2  Sudden weakness. 3  Severe joint pain.  Pain in 1  extremities. Abdominal cramps. 2  Fever. Spontaneous blood in the 3  urine. Nosebleed.  Neurological 1  manifestations. 2  Headache. Drowsiness.
Sickle cell disease (SCD) is a group of inherited disorders in which hemoglobin, the protein in red blood cells that carries oxygen, becomes hard and sticky and looks like a sickle. The symptoms of sickle cell disease include abdominal pain, bone pain, shortness of breath, delayed growth, fatigue, fever and chest pain.