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â¢ Sinus infection involves the sinus cavities of the skull, whereas the cold only involves the mucous membranes. â¢ Sinus infection is mainly due to bacterial, whereas the cold is due to viral agents. â¢ The headache in sinus infection is much heavier than in the cold, with the heaviness aggravating when bending forward.
Differences Between Sinusitis and Allergies. Itâs spring time and you have a stuffy nose, sinus pain, fatigue and reduced sense of smell and taste. You head to the local pharmacy for over the counter medication to treat your allergies. There is only one problem, these are the symptoms of a sinus infection, not allergies. Most allergy patients can't tell the difference, according to a recent survey by the Asthma and Allergy Foundation of America.