High PTH levels may be caused by: 1  A parathyroid gland growth (hyperplasia) or a parathyroid tumor. 2  A low level of calcium in the blood. 3  Some types of cancer, such as of the lung, kidney, pancreatic, or ovarian cancer.
MTOR inhibitors What are MTOR inhibitors. Mammalian target of rapamycin (mTOR) inhibitors block the activity of the mammalian target of rapamycin. Mammalian target of rapamycin is a protein kinase, which regulates growth factors that stimulate cell growth and angiogenesis. In certain cancers the mTOR pathway is more active. Mammalian target of rapamycin (mTOR) inhibitors are used in treatment of renal cancer and is being studied for use in other types of cancers.
Entrez Gene Summary for ALK Gene. This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain.ntrez Gene Summary for ALK Gene. This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain.