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There are two basic types of DNA testing that can be done before delivery. These include amniocentesis and CVS, or Chorionic Villus Sampling. An amniocentesis is generally performed during the second trimester of pregnancy. Typically, it would take place between the 14th and the 20th week of pregnancy.
Testing your baby after birth. A PKU test is done a day or two after your baby's birth. The test isn't done before the baby is 24 hours old or before the baby has ingested some protein in the diet to ensure accurate results.1  A nurse or lab technician collects a few drops of blood from your baby's heel or the bend in your baby's arm.ll 50 states in the United States require newborns to be screened for PKU. Many other countries also routinely screen infants for PKU. If you have PKU or a family history of it, your doctor may recommend screening tests before pregnancy or birth.