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â¢ Sinus infection involves the sinus cavities of the skull, whereas the cold only involves the mucous membranes. â¢ Sinus infection is mainly due to bacterial, whereas the cold is due to viral agents. â¢ The headache in sinus infection is much heavier than in the cold, with the heaviness aggravating when bending forward.
Breathe Easy. One of the clearest signs your cold is really a sinus infection is whether your symptoms get worse. When you have a cold, you can expect your symptoms to last less than 10 days. In contrast, sinus infections last for over a week, and some symptoms, like headaches and sinus pressure, may actually get worse. If you have treated a cold with over the counter medicine like advil and have not seen an improvement in your symptoms it is time to see a sinus specialist.