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â¢ Sinus infection involves the sinus cavities of the skull, whereas the cold only involves the mucous membranes. â¢ Sinus infection is mainly due to bacterial, whereas the cold is due to viral agents. â¢ The headache in sinus infection is much heavier than in the cold, with the heaviness aggravating when bending forward.
Article Body. It is often difficult to tell if an illness is just a viral cold or if it is complicated by a bacterial infection of the sinuses. Sinusitis is an inflammation of the lining of the nose and sinuses. It is a very common infection in children.1  Viral sinusitis usually accompanies a cold. 2  Allergic sinusitis may accompany allergies such as hay fever. 3  Bacterial sinusitis is a secondary infection caused by the trapping of bacteria in the sinuses during the course of a cold or allergy.rticle Body. It is often difficult to tell if an illness is just a viral cold or if it is complicated by a bacterial infection of the sinuses. Sinusitis is an inflammation of the lining of the nose and sinuses. It is a very common infection in children.