Freebase(0.00 / 0 votes)Rate this definition: Japan is an island nation in East Asia. Located in the Pacific Ocean, it lies to the east of the Sea of Japan, China, North Korea, South Korea and Russia, stretching from the Sea of Okhotsk in the north to the East China Sea and Taiwan in the south.
Signs and symptoms of neuroendocrine cancer. A sign is something that can be observed and recognized by a doctor or healthcare professional (for example, a rash). A symptom is something that only the person experiencing it can feel and know (for example, pain or tiredness).
Adrenal cancer symptoms The adrenal glands are a production center for regulatory hormones such as adrenaline and cortisone. For this reason, many of the symptoms of adrenal cancer are related to hormonal imbalances resulting from tumors secreting too much or too little of a particular hormone. A large percentage of tumors on the adrenal glands are benign. These tumors may grow very large and put pressure on nearby organs like the stomach, but they do not spread to other parts of the body. In such cases, patients may experience a feeling of fullness and unexplained weight loss.