When incompatible blood is given, antibodies and complement in the recipient plasma attack the antigens on the donor RBC. Hemolysis ensues The antigen-antibody complex activate the Hageman factor (factor XII), which acts on the kinin system to produce bradykinin
Still it is not advisable to take it after the expiry date written on the bottle. This is just for your information to let you know that you are safe. Anyway Saline Nasal spray is not going to do any harm even if you used an expired one. So forget about it.
So, do sprinkles expire? When properly stored, the shelf life of sprinkles past their sell by date or other printed date is ... This is regardless if they are open or unopened, as long as they have been sealed and stored properly. Sprinkles are good for 3 years beyond the code stamped on the bottle. Betty Crocker brand (actually made by Signature Brands) uses a code on the side of the plastic container instead of a use by date.