Another important site of histamine storage and release is the enterochromaffin-like (ECL) cell of the stomach. The most important pathophysiologic mechanism of mast cell and basophil histamine release is immunologic. These cells, if sensitized by IgE antibodies attached to their membranes, degranulate when exposed to the appropriate antigen.
Report Abuse. There are 4 seasons in America: Spring, Summer, Fall (Autumn), and Winter. In the Springtime, (February-May) the first season in the year, it is mildly warm and sometimes chilly. In the Summertime, (June-August) the second season of the year, it is hot and sunny.
The American series premiered on April 26, 2011 on the NBC television network. The winner of the first season was Javier Colon, mentored by coach Adam Levine, the finale airing on June 29, 2011. It immediately proved to be a hit for NBC and the network renewed the show for a second season.