If you smoke on the higher end of the temperature range subtract about 10 minutes per pound. This means a ten-pound pork shoulder can take 15 hours to finish. Many people find it difficult to maintain a good temperature for this long and choose to wrap the pork in foil and place it in the oven.
Non-tropic hormones behave in an opposite manner to tropic hormones. They act on target cells rather than on the endocrine glands. Non-tropic hormones are those that act directly on targeted tissues or cells, and not on other endocrine gland to stimulate release of other hormones. 1  Many hormones act in a chain reaction. Tropic hormones usually act in the beginning of the reaction stimulating other endocrine gland to eventually release non-tropic hormones. These are the ones that act in the end of the chain reaction on other cells that are not part of other endocrine gland.
1. Exocrine glands have ducts to carry hormones, while endocrine glands are ductless. 2. Exocrine hormones are released into the external environment, or outside of the body. Endocrine hormones are released into the internal environment, or inside of the body.