The source of the album's eventual centrepiece,  Layla , was rooted in Clapton's personal life; he had become infatuated with Pattie Boyd, the wife of his friend George Harrison. who had joined Clapton as a guitarist on Delaney & Bonnie's European tour in December 1969.
EB-1020 is a novel drug in Phase II clinical trials for the treatment of ADHD. It is under development by Neurovance, a spinout from Euthymics Biosciences. The drug is intended to function as a non-stimulant, acting as a triple reuptake inhibitor â preventing the reuptake of dopamine, norepinephrine, and serotonin.
-DOPA is a precursor for dopamine, which, in turn, is a precursor for the important neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline). Tyrosine hydroxylase catalyzes the rate limiting step in this synthesis of catecholamines.DOPA and the other one is used to hydroxylate the cofactor. Like the other aromatic amino acid hydroxylases (AAAHs), tyrosine hydroxylase use the cofactor tetrahydrobiopterin (BH 4) under normal conditions, although other similar molecules may also work as a cofactor for tyrosine hydroxylase.