In 1841 and 1842, the first two years of the Trail's use by emigrant parties, the overland route ended at Fort Walla Walla, at the mouth of the Walla Walla River. From there, emigrants rafted their wagons down the Columbia River to the Willamette River Valley.
I have been an insulin dependent diabetic for 20 years. I had my first ever cortison injection for a worn out knee. For 5 days after the injection my blood sugar levels ran between 450 and 600. No matter how much fast acting insulin I took, it would not go down.
Re: Prednisone's lasting effect on blood glucose. I haven't had a patient on it in a while but from what I remember the effects of the drug seem to wear off rather quickly. Possibly within 24 hrs of discontinuing it. What gets me is when the professionals administering the drug don't let the person with diabetes know that yes, this will raise your blood sugar.