A mutation is a permanent change in the DNA sequence of a gene. Mutations in a gene's DNA sequence can alter the amino acid sequence of the protein encoded by the gene.
Connectivity Map. This research effort aims to generate a detailed map that links gene patterns associated with disease to corresponding patterns produced by drug candidates and a variety of genetic manipulations.The Connectivity Map is the most comprehensive effort yet for using genomics in a drug-discovery framework.his research effort aims to generate a detailed map that links gene patterns associated with disease to corresponding patterns produced by drug candidates and a variety of genetic manipulations.
The distance between the genes (map units) are equal to the percentage of crossing-over events that occurs between different alleles. Gene mapping, describes the methods used to identify the locus of a gene and the distances between genes.The essence of all genome mapping is to place a collection of molecular markers onto their respective positions on the genome. Molecular markers come in all forms.Genes can be viewed as one special type of genetic markers in the construction of genome maps, and mapped the same way as any other markers.dentification of genes is usually the first step in understanding a genome of a species; mapping of the gene is usually the first step of identification of the gene. Gene mapping is usually the starting point of many important downstream studies.