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1 On average, a newborn drinks about 1.5-3 ounces (45-90 milliliters) every 2-3 hours. This amount increases as your baby grows and is able to take more at each feeding.  At about 2 months, your baby may be taking 4-5 ounces (120-150 milliliters) at each feeding and the feedings may be every 3-4 hours.
For example, a 12 pound baby would likely need 24 to 30 ounces in a 24 hour period. To determine how many ounces per bottle, divide those amounts by the number of feedings your baby takes per day. In this example, if your baby is taking 6 bottles in 24 hours, he would need approximately 4 to 5 ounce bottles.