Signs and symptoms of peripheral neuropathy might include: 1  Gradual onset of numbness, prickling or tingling in your feet or hands, which can spread upward into your legs and arms. 2  Sharp, jabbing, throbbing, freezing or burning pain.  Extreme sensitivity to touch.
Clinical Significance. Magnesium measurements are used in the diagnosis and treatment of hypomagnesemia (abnormally low plasma levels of magnesium) and hypermagnesemia (abnormally high plasma levels of magnesium). Magnesium is decreased in chronic nephritis, acute pancreatitis, and alcoholic cirrhosis.
The diagnosis should be confirmed with a repeat serum potassium measurement. Other laboratory tests include serum glucose and magnesium levels, urine electrolyte and creatinine levels, and acid-base balance.