By Carolyn L. Driedger and William E. Scott, USGS -- Republished from USGS fact sheet 2008-3062. 1  Mount Rainier: The flat floor of the Puyallup River valley near Orting, Washington, is formed by deposits of the 500-year-old Electron lahar, which surged down from Mount Rainier (in background).
Substitution mutation. Definition. A type of point mutation in which a single nucleotide is substituted with (or exchanged for) a different nucleotide that may result in an altered sequence of amino acid during translation, which may render the newly synthesized protein ineffective.Supplement.n transversion, purine is substituted with pyrimidine or a pyrimidine with a purine. See also: point mutation. Please contribute to this project, if you have more information about this term feel free to edit this page. This page was last modified on 16 October 2008, at 00:53.This page has been accessed 109,894 times.
This image shows an example of missense mutation. One of the nucleotides (adenine) is replaced by another nucleotide (cytosine) in the DNA sequence. This results in an incorrect amino acid (proline) being incorporated into the protein sequence.In genetics, a missense mutation (a type of nonsynonymous substitution) is a point mutation in which a single nucleotide change results in a codon that codes for a different amino acid.hen an amino acid may be encoded by more than one codon (so-called degenerate coding) a mutation in a codon may not produce any change in translation; this would be a silent mutation (a type of synonymous substitution, which is not always silent) and not a missense mutation.