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Carpal tunnel: Carpal tunnel syndrome is one of the most common causes of numbness in the hands (palms and fingers). Usually, the thumb, index and middle fingers are involved, but frequently people report numbness in the entire hand. Wearing wrist splints at night usually helps. You may want to try those.
Causes. Numbness in a hand is usually caused by damage, irritation or compression of one of the nerves or a branch of one of the nerves in your arm and wrist. Diseases affecting the peripheral nerves, such as diabetes, also can cause numbness, although this is often preceded by similar symptoms in your feet.Rarely, numbness can be caused by problems in your brain or spinal cord, although this is usually accompanied by weakness or loss of function in your arm or hand.iseases affecting the peripheral nerves, such as diabetes, also can cause numbness, although this is often preceded by similar symptoms in your feet. Rarely, numbness can be caused by problems in your brain or spinal cord, although this is usually accompanied by weakness or loss of function in your arm or hand.