When incompatible blood is given, antibodies and complement in the recipient plasma attack the antigens on the donor RBC. Hemolysis ensues The antigen-antibody complex activate the Hageman factor (factor XII), which acts on the kinin system to produce bradykinin
Three years. The month and year of expiration is reflected on the individual packets and the outside of the box directly under the âDrug Factsâ section. Due to the high demand, all of our saline has been purchased long before it approaches expiration. more.
Quote from lpnandloveit1 I have always been told that the manufacturers exp date was for sealed unopened vials. Jun 9, '05. All multi-dose vials are marked when opened, usually insulin and such have a 30 day expiration date from date opened, but they never lasted that long on any unit I worked. If there is a change in color, nature, or if nurse feels vial was unsafe they were tossed.