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In addition to fatigue, people who are vitamin B-12-deficient can experience a wide range of symptoms. They may have dizziness, headache, shortness of breath, cold extremities, skin discoloration and/or chest pain. Vitamin B-12 deficiency can also lead to weakened bones and difficulty maintaining balance. Confusion, dementia, depression and impacted memory may also occur.
Data on taking vitamin C for hypertension are also mixed. Taking vitamin C with antihypertensive medications may slightly decrease systolic blood pressure, but not diastolic pressure. Supplemental vitamin C -- 500 mg per day taken without antihypertensives -- doesn't seem to reduce systolic or diastolic blood pressure. Type 2 diabetics who supplemented with vitamin C and remained on their antihypertensive medications seemed to have a reduction in blood pressure and arterial stiffness.