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The mononuclear phagocyte system constitutes macrophage cells spread throughout the human body. The macrophages are long-lived cells that provide a major defense system against hostile elements through phagocytosis and subsequent intracellular destruction of the particle or cell.
Nearly 90% of Americans have antibodies for mononucleosis by age 40. Mono has an incubation period of 30 to 40 days and the symptoms usually last 7 to 14 days but can last for several weeks. The virus can stay alive within the body for several months. The name mononucleosis comes from the fact that the disease distorts the white blood cells, causing them to only have one nucleus.