One common cause of hyperprolactinemia is a growth or tumor on the pituitary gland called a prolactinoma. The tumor produces high levels of prolactin. These tumors can be large or small and are usually benign, meaning they are not cancerous. Large tumors can also cause headaches, vision problems, or both.
The most common symptoms of atypical antidepressant withdrawal, including Cymbalta, are anxiety and low mood, such as apathy and rebound depression. Because Cymbalta strongly affects serotonin, after discontinuation it can take several days for the body's own serotonin system to return to normal.
According to Lillyâs own analysis of the Cymbalta studies, after a two week withdrawal period, over 50% of patients were still experiencing withdrawal side effects. Just how long the withdrawal effects lasted for those patients is unknown because Lilly never evaluated the effects of Cymbalta withdrawal beyond two weeks.