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Sudafed (pseudoephedrine) and other decongestants can cause erectile dysfunction (ED) in some men. If you are having trouble getting or maintaining an erection while taking Sudafed, your doctor or pharmacist can recommend a different medication.
Pseudoephedrine is in a class of medications called nasal decongestants, which cause smooth muscles around the airway and nasal cavity to relax, allowing more air to flow through. It also causes blood vessels to contract.t's used to temporarily relieve nasal congestion from colds, allergies, and hay fever, and temporarily relieve sinus congestion and pressure. Though it can relieve symptoms, pseudoephedrine doesn't treat or speed the recovery of the underlying health condition.