In both sleep laboratory and outpatient studies, elderly patients with insomnia responded to a 5 mg dose with a reduced sleep latency, and thus 5 mg is the recommended dose in this population. During short-term treatment (14 night studies) of elderly patients with Sonata, no adverse event with a frequency of at least 1% occurred at a significantly higher rate with either 5 mg or 10 mg Sonata than with placebo.
As in all other cells, the resting potential of a pacemaker cell (-60mV to -70mV) is caused by a continuous outflow or leak of potassium ions through ion channel proteins in the membrane that surrounds the cells.hese cells form the atrioventricular node (or AV node), which is an area between the left atrium and the right ventricle within the atrial septum, will take over the pacemaker responsibility. The cells of the AV node normally discharge at about 40-60 beats per minute, and are called the secondary pacemaker.
Cancer Cell Properties. Cancer cells have characteristics that differ from normal cells. 1  Cell Reproduction: Cancer cells acquire the ability to reproduce uncontrollably. 2  These cells may have gene mutations or chromosome mutations that affect the reproductive properties of the cells. Normal cells reproduce properly. 2  Except for sex cells, all cells of the body reproduce by mitosis. 3  Sex cells reproduce through a process called meiosis. 4  Cell Communication: Cells communicate with other cells through chemical signals. 5  These signals help normal cells to know when to reproduce and when to stop reproducing.