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Leukemia is a type of cancer that affects the blood and bone marrow. Leukemia begins in a cell in the bone marrow. The cell undergoes a change and becomes a type of leukemia cell. Once the marrow cell undergoes a leukemic change, the leukemia cells may grow and survive better than normal cells.
Sometimes, too many myeloid stem cells develop into abnormal red blood cells or platelets. Leukemia can involve tissues outside the bone marrow and blood, including lymph nodes, brain, skin and other parts of the body. AML can happen at any age. But the risk increases with older age. Until age 50, men and women are equally affected.