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Overview. 1  Quinine, a bitter tasting powder made from the bark of the cinchona tree, is known mainly for its use in malaria treatment. 2  Tonic water, a bitter liquid sometimes used as a mix for alcoholic drinks, contains only a small amount of quinine compared to quinine medications.
Quinine is still used to treat malaria today, although doctors typically reserve it for cases when the pathogen responsible for the disease displays resistance to newer drugs. However, you'd have to drink almost 20 liters of today's dilute tonic water daily to achieve the daily dose typically prescribed for malaria.