Cardiac action potential. The cardiac action potential is a brief change in voltage (membrane potential) across the cell membrane of heart cells. This is caused by the movement of charged atoms (called ions) between the inside and outside of the cell, through proteins called ion channels.
Smoke's Poutinerie is a Canadian nationwide poutine franchise founded by entrepreneur Ryan Smolkin. Founded in Toronto in 2008, its premiere location was the first poutine-exclusive restaurant in that town. Smolkin was inspired by Montreal restaurant La Banquise, which serves many different kinds of poutine. Smolkin frequents La Banquise whenever he visits Montreal.
In 1611 Rolfe, known as an ardent smoker, decided to experiment with cultivating tobacco in Jamestown. The plant had first been brought to England in 1565, perhaps from Florida by Sir John Hawkins, and by the 1610s there was a ready market in Britain for tobaccoâespecially Spanish tobacco from the West Indies.