A mutation is a permanent change in the DNA sequence of a gene. Mutations in a gene's DNA sequence can alter the amino acid sequence of the protein encoded by the gene.
Connectivity Map. This research effort aims to generate a detailed map that links gene patterns associated with disease to corresponding patterns produced by drug candidates and a variety of genetic manipulations.The Connectivity Map is the most comprehensive effort yet for using genomics in a drug-discovery framework.his research effort aims to generate a detailed map that links gene patterns associated with disease to corresponding patterns produced by drug candidates and a variety of genetic manipulations.
At a low resolution, DNA can be mapped at the level of banding patterns that roughly show the distance between two genes after a chromosome has been stained with dye. Genetic mapping or linkage mapping can be used to indicate the relative order of genes on a chromosome.