Recent News. Bartolo Colon held the Padres to one hit over seven innings of one-run ball Sunday in the Braves' 9-2 victory. The only hit he allowed was a Ryan Schimpf solo homer in the top of the second inning. Colon struck out six and issued just one walk in the dominant outing, dropping his season ERA from 6.30 to 4.24. He'll carry a 1-1 record into his next start on the road against the Phillies, a very familiar foe. Apr 16 - 5:42 PM. Bartolo Colon was tagged for six runs in four innings by the Marlins on Tuesday.
Rupatadine is a novel substance which, in addition to being an H1 antagonist, is also a potent platelet-activating factor (PAF) inhibitor. It belongs to the N-alkyl pyridine derivates. Animal and human models [2] have shown rupatadine to have dual antihistamine and PAF-antagonist properties.
Bendamustine is a white, water-soluble microcrystalline powder with amphoteric properties. It acts as an alkylating agent causing intra-strand and inter-strand cross-links between DNA bases. After intravenous infusion it is extensively metabolised in the liver by cytochrome p450.More than 95% of the drug is bound to protein-primarily albumin. Only free bendamustine is active. Elimination is biphasic with a half-life of 6â10 minutes and a terminal half-life of approximately 30 minutes.It is eliminated primarily through the kidneys.endamustine is a white, water-soluble microcrystalline powder with amphoteric properties. It acts as an alkylating agent causing intra-strand and inter-strand cross-links between DNA bases. After intravenous infusion it is extensively metabolised in the liver by cytochrome p450.