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Sudafed (pseudoephedrine) and other decongestants can cause erectile dysfunction (ED) in some men. If you are having trouble getting or maintaining an erection while taking Sudafed, your doctor or pharmacist can recommend a different medication.
A Dr. Mehmet Oz, MD , Cardiology (Cardiovascular Disease), answered. There are blood pressure medications that do not cause erectile dysfunction (ED). Some older blood pressure medications, especially beta blockers and thiazide diuretics, are the most likely to cause ED as a side effect.