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In terms of cause and effect, a root cause is the cause of symptoms and a symptom stemming from a root cause is the effect of the root cause. There is no entity disease involved in cause and effect.
Detailed Synonyms for root cause in English. root cause: root cause [the ~] noun. the root cause the root cause; the main reason; the fundamental cause; the principal cause; the main ground; the basic cause root cause [the ~] noun. main reason [the ~] noun. fundamental cause [the ~] noun. principal cause [the ~] noun. main ground [the ~] noun.