In mitral valve disease, the mitral valve, which is located between your left heart chambers (left atrium and left ventricle), doesn't work properly. Types of mitral valve disease include:Mitral valve regurgitation. In this condition, the flaps (leaflets) of the mitral valve don't close tightly, causing blood to leak backward into the left atrium of your heart. If not treated, it can result in heart muscle damage.The most common cause of blood leakage is mitral valve prolapse, in which the leaflets bulge back into the left atrium as your heart contracts. 1  Mitral valve stenosis. 2  In this condition, the flaps of the mitral valve become thick or stiff, and they may fuse together. Mitral valve stenosis. 2  In this condition, the flaps of the mitral valve become thick or stiff, and they may fuse together. 3  This results in a narrowed valve opening and reduced blood flow from the left atrium to the left ventricle.
The Cuyahoga River and the industrial flats. The Flats is a mixed-use industrial, entertainment, and increasingly residential area of Cleveland, Ohio, USA. The name reflects its low-lying topography on the banks of the Cuyahoga River.
There are salt flats found around the world but some of the largest examples include the Salar de Uyuni in Bolivia, the Bonneville Salt Flats in the state of Utah and those found in Californiaâs Death Valley National Park.