In 1841 and 1842, the first two years of the Trail's use by emigrant parties, the overland route ended at Fort Walla Walla, at the mouth of the Walla Walla River. From there, emigrants rafted their wagons down the Columbia River to the Willamette River Valley.
I have been an insulin dependent diabetic for 20 years. I had my first ever cortison injection for a worn out knee. For 5 days after the injection my blood sugar levels ran between 450 and 600. No matter how much fast acting insulin I took, it would not go down.
As a matter of fact about 60 % of diabetics (an ailment that is often characterized with high blood sugar levels that the body has a tough time controlling) also are regularly plagued with constipation. Here's why: Blood Sugar Impact. High blood sugar levels in the body can impact the body's nervous system. This impact on the nervous system means the nerves are less likely to do their job properly and the brain is having a tough time passing on messages to the nerves.