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Sudafed (pseudoephedrine) and other decongestants can cause erectile dysfunction (ED) in some men. If you are having trouble getting or maintaining an erection while taking Sudafed, your doctor or pharmacist can recommend a different medication.
Both pseudoephedrine and phenylephrine can cause side effects. Call your doctor if you have any serious side effects when using these drugs. The chart below lists examples of possible side effects from pseudoephedrine and phenylephrine. Common side effects