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About the time of birth in mammals, a secondary ossification center appears in each end (epiphysis) of long bones. Periosteal buds carry mesenchyme and blood vessels in and the process is similar to that occurring in a primary ossification center.
Place in order the steps involved in endochondral ossification: (1) nutrient artery invades teh periosteum (2) osteoclasts creat a marrow cavity (3) chondrocytes enlarge and secrete alkaline phosphatase (4) secondary ossification centers appear in the epiphysis (5) cartilage matrix becomes mineralized (6)... show more Place in order the steps involved in endochondral ossification: (1) nutrient artery invades teh periosteum. (2) osteoclasts creat a marrow cavity. (3) chondrocytes enlarge and secrete alkaline phosphatase. (4) secondary ossification centers appear in the epiphysis. (5) cartilage matrix becomes mineralized.