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Overview. 1  Quinine, a bitter tasting powder made from the bark of the cinchona tree, is known mainly for its use in malaria treatment. 2  Tonic water, a bitter liquid sometimes used as a mix for alcoholic drinks, contains only a small amount of quinine compared to quinine medications.
In some cases, you may need to take a different medication (such as primaquine) to kill the malaria parasites living in other body tissues. Both drugs may be needed for a complete cure and to prevent the return of infection (relapse). Quinine belongs to a class of drugs known as antimalarials.