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Causes. Ischemic cardiomyopathy is weakness in the muscle of the heart due to coronary artery disease. Individuals with ischemic cardiomyopathy typically have a history of myocardial infarction (heart attack). Nonischemic cardiomyopathy is weakness in the muscle of the heart that is not due to coronary artery disease.ndividuals with ischemic cardiomyopathy typically have a history of myocardial infarction (heart attack). Nonischemic cardiomyopathy is weakness in the muscle of the heart that is not due to coronary artery disease.
Ischemic heart disease is characterized by a reduction in blood supply and oxygen to the heart. Undiagnosed cases of ischemic heart disease can result in massive heart attacks. Ischemic heart disease is defined by deposits of plaque along the walls of the coronary arteries.When patientâs ischemic heart disease is severe, they may opt for a balloon angioplasty.ssentially, you can define ischemic heart disease as deposits of fat or plaque that occur in the walls of the coronary arteries. Because these deposits reduce blood flow to the heart, several things can occur.