The source of the album's eventual centrepiece,  Layla , was rooted in Clapton's personal life; he had become infatuated with Pattie Boyd, the wife of his friend George Harrison. who had joined Clapton as a guitarist on Delaney & Bonnie's European tour in December 1969.
EB-1020 is a novel drug in Phase II clinical trials for the treatment of ADHD. It is under development by Neurovance, a spinout from Euthymics Biosciences. The drug is intended to function as a non-stimulant, acting as a triple reuptake inhibitor â preventing the reuptake of dopamine, norepinephrine, and serotonin.
The 5-HT1B receptor as an example of a metabotropic serotonin receptor. The serotonin receptors, also known as 5-hydroxytryptamine receptors or 5-HT receptors, are a group of G protein-coupled receptors (GPCRs) and ligand-gated ion channels (LGICs) found in the central and peripheral nervous systems. They mediate both excitatory and inhibitory neurotransmission.