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The main contractile system of all muscular tissue are based on the interactions of two proteins Actin and Myosin. The system of these proteins some times called actin-myosin contractile system. Actin is one of the most condensed forms of protein, which is globular and is a monomeric subunit of microfilament. The thin filaments in actin constitute a major part of it.
1 Thick filaments consist primarily of the protein myosin, held in place by titin filaments. 2  Myosin is responsible for force generation. 3  It is composed of a globular head with both ATP and actin binding sites, and a long tail involved in its polymerization into myosin filaments. Thin filaments consist primarily of the protein actin, coiled with nebulin filaments. 2  Actin, when polymerized into filaments, forms the ladder along which the myosin filaments climb to generate motion. 3  Thick filaments consist primarily of the protein myosin, held in place by titin filaments.