The source of the album's eventual centrepiece,  Layla , was rooted in Clapton's personal life; he had become infatuated with Pattie Boyd, the wife of his friend George Harrison. who had joined Clapton as a guitarist on Delaney & Bonnie's European tour in December 1969.
EB-1020 is a novel drug in Phase II clinical trials for the treatment of ADHD. It is under development by Neurovance, a spinout from Euthymics Biosciences. The drug is intended to function as a non-stimulant, acting as a triple reuptake inhibitor â preventing the reuptake of dopamine, norepinephrine, and serotonin.
This enzyme provides the rate-limiting step for serotonin synthesis, in the same manner that norepinephrine and dopamine synthesis in adrenergic and dopaminergic neurons is controlled by the ability of the related enzyme, L-tyrosine hydroxylase, to convert L-tyrosine to L-dihydroxyphenylalanine (L-DOPA).