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Overview. 1  Quinine, a bitter tasting powder made from the bark of the cinchona tree, is known mainly for its use in malaria treatment. 2  Tonic water, a bitter liquid sometimes used as a mix for alcoholic drinks, contains only a small amount of quinine compared to quinine medications.
Tonic water was never intended as a cure or preventive for malaria, but malaria is the reason the quinine is in there. Quinine has a bitter taste. To make the stuff palatable when used as an antidote for fevers, legend has it, British colonials in India mixed quinine with gin and lemon or lime.onic water contains less than 20 milligrams of quinine per six fluid ounces. The recommended quinine dosage for treatment of malaria is two or three 200-350 milligram tablets three times a day.