When incompatible blood is given, antibodies and complement in the recipient plasma attack the antigens on the donor RBC. Hemolysis ensues The antigen-antibody complex activate the Hageman factor (factor XII), which acts on the kinin system to produce bradykinin
Still it is not advisable to take it after the expiry date written on the bottle. This is just for your information to let you know that you are safe. Anyway Saline Nasal spray is not going to do any harm even if you used an expired one. So forget about it.
Label the medication vial with the date and. time opened, the initials of the person. opening the vial, and the expiration date of. the vial, not to exceed 28 days. If the manufacturerâs expiration date occurs. prior to the 28th day, the manufacturerâs. expiration date must be used. Some. medications may indicate an expiration date of. less than 28 days once the vial has been. accessed.