A mutation is a permanent change in the DNA sequence of a gene. Mutations in a gene's DNA sequence can alter the amino acid sequence of the protein encoded by the gene.
Connectivity Map. This research effort aims to generate a detailed map that links gene patterns associated with disease to corresponding patterns produced by drug candidates and a variety of genetic manipulations.The Connectivity Map is the most comprehensive effort yet for using genomics in a drug-discovery framework.his research effort aims to generate a detailed map that links gene patterns associated with disease to corresponding patterns produced by drug candidates and a variety of genetic manipulations.
The distance between the genes (map units) are equal to the percentage of crossing-over events that occurs between different alleles. Gene mapping, describes the methods used to identify the locus of a gene and the distances between genes.he distance between the genes (map units) are equal to the percentage of crossing-over events that occurs between different alleles. Gene mapping, describes the methods used to identify the locus of a gene and the distances between genes.