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It is believed that itching may worsen at night due to the various changes in the circadian rhythm. The circadian rhythm is the bodyâs âinternal clockâ of sorts where different biological processes seem to correlate with a 24 hour period on a daily basis.
Tweet. There are many reasons for itching. Something is irritating your skin. It could be something you came in contact with or some waste product or toxin trying to work its way out of your body. There could be an infection in the skin. Many people itch when they get too stressed out or worn down. In response to such skin stressors your mast cells may release histamine (an irritant chemical), that magnifies the itching response.