Don t play this piece fast. It is never right to play ragtime fast. -- Scott Joplin When I'm dead twenty-five years, people are going to begin to recognize me. -- Scott Joplin Let me see you do the 'rag time dance'... Turn left and do the 'Cake walk prance'... Turn the other way and do the 'Slow drag'... Now take your lady to the world's fair (...) And do the 'rag time dance.'  -- Scott Joplin Because it has such a ragged movement.
When the stress response is ongoing other minerals can actually build up in the body, such as potassium, sodium and phosphorous. This is due to a change in intestinal absorption (since digestion takes a back seat when we are in fight-or-flight mode) and re-absorption by the kidneys of these elements.
Stress causes the release of a hormone called cortisol. Giving rats daily injections of corticosterone (rat cortisol) for several weeks kills certain brain cells. Stressing the rats each day for the same amount of time has an identical effect. Cortisol has been shown to damage and kill cells in the hippocampus (the brain area responsible for your episodic memory) and there is robust evidence that chronic stress causes premature brain aging.