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Leukemia is a type of cancer that affects the blood and bone marrow. Leukemia begins in a cell in the bone marrow. The cell undergoes a change and becomes a type of leukemia cell. Once the marrow cell undergoes a leukemic change, the leukemia cells may grow and survive better than normal cells.
Eventually, these cells can overwhelm the bone marrow, spill out into the bloodstream and spread to other organs. There are four common types of leukemia based on how quickly the disease develops and the type of white blood cell that is affected. In acute leukemia blood cells are very abnormal, increase rapidly and worsen quickly.