Another important site of histamine storage and release is the enterochromaffin-like (ECL) cell of the stomach. The most important pathophysiologic mechanism of mast cell and basophil histamine release is immunologic. These cells, if sensitized by IgE antibodies attached to their membranes, degranulate when exposed to the appropriate antigen.
Report Abuse. There are 4 seasons in America: Spring, Summer, Fall (Autumn), and Winter. In the Springtime, (February-May) the first season in the year, it is mildly warm and sometimes chilly. In the Summertime, (June-August) the second season of the year, it is hot and sunny.
As of November 16, 2016, 73 episodes of American Horror Story have aired, concluding the sixth season. In October 2016, the series was renewed for a seventh season, to premiere in September 2017. In January 2017, the series was renewed for an eighth and ninth season. 1 Series overview.