A mutation is a permanent change in the DNA sequence of a gene. Mutations in a gene's DNA sequence can alter the amino acid sequence of the protein encoded by the gene.
Connectivity Map. This research effort aims to generate a detailed map that links gene patterns associated with disease to corresponding patterns produced by drug candidates and a variety of genetic manipulations.The Connectivity Map is the most comprehensive effort yet for using genomics in a drug-discovery framework.his research effort aims to generate a detailed map that links gene patterns associated with disease to corresponding patterns produced by drug candidates and a variety of genetic manipulations.
A general definition of process mapping is an analysis of the details of the process to see whether or not it is effective. Step 1. Establish the boundaries of the activity or activities that you want to examine. In other words, identify the process that you are analyzing, and explain why.