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These diseases and conditions may be more likely causes of Loose stool if the patient has diabetes, is at risk of diabetes, or has a family history of diabetes. 1  Traveler's diarrhea - loose stool.  Urinary tract infections - loose stool.
Diabetic nephropathy -- kidney disease that results from diabetes -- is the number one cause of kidney failure. Almost a third of people with diabetes develop diabetic nephropathy. People with diabetes and kidney disease do worse overall than people with kidney disease alone.