Another important site of histamine storage and release is the enterochromaffin-like (ECL) cell of the stomach. The most important pathophysiologic mechanism of mast cell and basophil histamine release is immunologic. These cells, if sensitized by IgE antibodies attached to their membranes, degranulate when exposed to the appropriate antigen.
Report Abuse. There are 4 seasons in America: Spring, Summer, Fall (Autumn), and Winter. In the Springtime, (February-May) the first season in the year, it is mildly warm and sometimes chilly. In the Summertime, (June-August) the second season of the year, it is hot and sunny.
One model suggests the first season of American Dad! comprises the first 7 episodes, while another model suggests the first season comprises 23 episodes. TBS picked up the series for the 12th season following the final 3 episodes airing on Fox as the 11th season. American Dad!'s TBS run began on October 20, 2014. TBS has also renewed the series for a 22-episode as 13th season, which premiered on January 25, 2016. On August 27, 2015, TBS announced it had picked up American Dad! for a 14th and 15th season of 22 episodes each.