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Sudafed (pseudoephedrine) and other decongestants can cause erectile dysfunction (ED) in some men. If you are having trouble getting or maintaining an erection while taking Sudafed, your doctor or pharmacist can recommend a different medication.
1 Review. Pseudoephedrine is a drug found in numerous prescription and behind-the-counter medications, including Sudafed Congestion (but not Sudafed PE), Zyrtec-D, and Claritin-D.It's used to temporarily relieve nasal congestion from colds, allergies, and hay fever, and temporarily relieve sinus congestion and pressure.Though it can relieve symptoms, pseudoephedrine doesn't treat or speed the recovery of the underlying health condition.t's used to temporarily relieve nasal congestion from colds, allergies, and hay fever, and temporarily relieve sinus congestion and pressure. Though it can relieve symptoms, pseudoephedrine doesn't treat or speed the recovery of the underlying health condition.