Sense of course of a working life first attested 1803. v. 1590s, to charge at a tournament, from career (n.). The meaning move rapidly, run at full speed (1640s) is from the image of a horse passing a career on the jousting field, etc. Related: Careered; careering.
Contractions of the stomach muscle, called peristaltic waves, grind, crush and mix the food producing a liquefied substance called chyme.. The pyloric sphincter separates the stomach from the duodenum. This valve keeps food and gastric juices in the stomach until liquefied enough to proceed into the duodenum.
1 It is divided into the pyloric antrum which lies next to the body and the pyloric canal which lies next to the duodenum.  The passage of food from the stomach into the duodenum is regulated by the pyloric sphincter.