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Itching hands and feet may be caused by a reaction to something in the diet or may be due to a more serious condition, such as diabetes. Vitamin toxicity may also cause itching skin in some people.
By Mayo Clinic Staff. Hand numbness is usually caused by damage, irritation or compression of one of the nerves or a branch of one of the nerves in your arm and wrist. Diseases affecting the peripheral nerves, such as diabetes, also can cause numbness, although with diabetes similar symptoms usually occur first in your feet.