Grapefruit varieties are red, pink or white in color and may come with seeds or may be seedless. Its size may vary from four to six inches round. The red and pink colored grapefruits have higher calories compared to the white. Also, the larger fruits have more calories than the smaller ones.
Summary. 1  Loss of appetite can cause fatigue due to low calorie intake and nutrient deficiency. 2  Fatigue means being constantly tired. 3  It may be a sign of an underlying health condition if youâre feeling fatigue, loss of appetite, and other symptoms such as vomiting and bloating.
Some hormone problems may cause overweight and obesity, such as underactive thyroid (hypothyroidism), Cushing's syndrome, and polycystic ovarian syndrome (PCOS). Underactive thyroid is a condition in which the thyroid gland doesn't make enough thyroid hormone. Lack of thyroid hormone will slow down your metabolism and cause weight gain. You'll also feel tired and weak. Cushing's syndrome is a condition in which the body's adrenal glands make too much of the hormone cortisol.