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Medical Definition of degenerative. : of, relating to, involving, or tending to cause degeneration degenerative conditions of the nervous systemâMorris Fishbein degenerative changes a degenerative muscle disorder.
Full Definition of DEGENERATE. 1. a: having declined or become less specialized (as in nature, character, structure, or function) from an ancestral or former state b: having sunk to a condition below that which is normal to a type; especially: having sunk to a lower and usually corrupt and vicious state c: degraded 2.2. 3.ull Definition of DEGENERATE. intransitive verb. 1. : to pass from a higher to a lower type or condition: deteriorate. 2. : to sink into a low intellectual or moral state. 3. 4. : to decline from a condition or from the standards of a species, race, or breed.