In 1841 and 1842, the first two years of the Trail's use by emigrant parties, the overland route ended at Fort Walla Walla, at the mouth of the Walla Walla River. From there, emigrants rafted their wagons down the Columbia River to the Willamette River Valley.
I have been an insulin dependent diabetic for 20 years. I had my first ever cortison injection for a worn out knee. For 5 days after the injection my blood sugar levels ran between 450 and 600. No matter how much fast acting insulin I took, it would not go down.
Effect of long stress on blood glucose levels. It is important to be aware that repeated episodes of stress can cause serious changes in blood sugar levels, making it harder for diabetics to manage their condition and increasing the risk of hypoglycemia (low blood sugar).