1 Two different mutations in the FGFR3 gene cause more than 99 per cent of cases of achondroplasia. 2  It is a dominant genetic disease so only one copy of the FGFR3 gene needs to be mutated for symptoms to develop. 3  Achondroplasia can be inherited from a parent with the disease.chondroplasia is a genetic disorder affecting bone development that results in short-limb dwarfism. 1  Achondroplasia is the most common form of short-limb dwarfism, a disorder in which bone tissue does not develop properly, especially the long bones of the arms and legs.
Common symptoms include fever, rash, joint pain, and conjunctivitis (redness of the eyes). In Brazil, the viral infection has been linked to birth defects (mainly small head and small brain size, termed microcephaly) in babies (newborns) whose mothers became infected with Zika virus during their pregnancy.
If the infected mosquito lives long enough for the virus to multiply, the mosquito can then bite another person to pass on the virus. People who are infected but who are not sick can still pass the virus on to mosquitoes that bite them. Zika virus can also spread from a mother to her baby during pregnancy or around the time of birth. Zika virus can spread through unprotected sex, such as not using condoms during sex, from a person who has Zika to his or her sex partners, even if the infected person is not sick. The virus can also be spread through blood transfusion. Who gets Zika?