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Sudafed (pseudoephedrine) and other decongestants can cause erectile dysfunction (ED) in some men. If you are having trouble getting or maintaining an erection while taking Sudafed, your doctor or pharmacist can recommend a different medication.
Pseudoephedrine is a decongestant found in many different medications. It comes most commonly as either pseudoephedrine sulfate or pseudoephedrine hydrochloride (there are no important differences between the two).Pseudoephedrine is especially useful for the following uses: 1  Relieving nasal congestion due to allergies (such as hay fever) or the common cold.2  Relieving sinus congestion and pressure.t comes most commonly as either pseudoephedrine sulfate or pseudoephedrine hydrochloride (there are no important differences between the two). Pseudoephedrine is especially useful for the following uses: 1  Relieving nasal congestion due to allergies (such as hay fever) or the common cold.