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Put the following steps of Koch's postulates in order: a. The suspected infectious agent must be isolated and grown outside the host. b. The suspected infectious agent causes the disease when it is introduced to a healthy, experimental host. c. The suspected infectious agent must be found in every case of the disease.
Because of its intracellular location the parasite has an intimate relationship with its host cell which can be described at the cellular and molecular levels. In particular, the parasite must enter the host cell, and once inside, it modifies the host cell.