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The main contractile system of all muscular tissue are based on the interactions of two proteins Actin and Myosin. The system of these proteins some times called actin-myosin contractile system. Actin is one of the most condensed forms of protein, which is globular and is a monomeric subunit of microfilament. The thin filaments in actin constitute a major part of it.
Calcium is required by two proteins, troponin and tropomyosin, that regulate muscle contraction by blocking the binding of myosin to filamentous actin. In a resting sarcomere, tropomyosin blocks the binding of myosin to actin.irst, the action of the reaching myosin S1 head uses the energy released after the ATP molecule is broken into ADP and phosphate. Myosin binds actin in this extended conformation. Second, the release of the phosphate empowers the contraction of the myosin S1 region (Figure 4).