Signs and symptoms of peripheral neuropathy might include: 1  Gradual onset of numbness, prickling or tingling in your feet or hands, which can spread upward into your legs and arms. 2  Sharp, jabbing, throbbing, freezing or burning pain.  Extreme sensitivity to touch.
Clinical Significance. Magnesium measurements are used in the diagnosis and treatment of hypomagnesemia (abnormally low plasma levels of magnesium) and hypermagnesemia (abnormally high plasma levels of magnesium). Magnesium is decreased in chronic nephritis, acute pancreatitis, and alcoholic cirrhosis.
Poikilocytosis may be diagnosed during a test called a blood smear. This test may be done during a routine physical exam, or if youâre experiencing unexplained symptoms. During a blood smear, a doctor spreads a thin layer of blood on a microscope slide and stains the blood to help differentiate the cells.