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There are several potential culprits behind canine urinary incontinence: 1  Bladder infections, stones, polyps or tumors. 2  Overflow incontinence, which occurs when a dog is affected by a medical condition that causes her to drink excessively, such as diabetes and Cushingâs disease. 3  Spinal cord disease.
Larger dogs (over 33 lbs) were about 7 times more likely to develop incontinence after spaying than smaller dogs. See Evaluation of the prevalence of urinary incontinence in spayed female dogs: 566 cases (2003â2008) for more information.] Estrogen responsive incontinence or hormonally responsive incontinence, commonly called spay incontinence, is the most frequent cause of involuntary urination in dogs.