The filament in a light bulb is housed in a sealed, oxygen-free chamber to prevent combustion. In the first light bulbs, all the air was sucked out of the bulb to create a near vacuum -- an area with no matter in it. Since there wasn't any gaseous matter present (or hardly any), the material could not combust.
Sertraline is used for a number of conditions including: major depression, obsessive-compulsive disorder (OCD), body dysmorphic disorder (BDD), posttraumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), panic disorder and social phobia (social anxiety disorder).
Plaquenil (hydroxychloroquine) is a medication most known for its original purpose of treating or preventing malaria, (a disease caused by parasites that enter the body through the bite of a mosquito).