1. the act of perceiving; observation; attention: to escape notice. 2. take notice to pay attention; attend. 3. take no notice of to ignore or disregard. 4. information about a future event; warning; announcement. 5. a displayed placard or announcement giving information.
Nicotine: A Stimulant Nicotine, the chemical that makes addicts out of cigarette smokers, is a stimulant with properties similar to those of cocaine and amphetamine (speed). Nicotine provides the pick-me-up that smokers feel.
Nicotine seems to provide both a stimulant and a depressant effect, and it is likely that the effect it has at any time is determined by the mood of the user, the environment and the circumstances of use. Studies have suggested that low doses have a depressant effect, whilst higher doses have stimulant effect.