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Rating Newest Oldest. Best Answer: Denaturation is a process in which proteins or nucleic acids lose their structure by application of some external stress or compound. If proteins in a living cell are denatured, this results in disruption of cell activity and possibly cell death. Source(s): http://en.wikipedia.org/wiki/Denaturatio...
Once the denaturing agent is removed, the original interactions between amino acids return the protein to its original conformation and it can resume its function. However, denaturation can be irreversible in extreme situations, like frying an egg.