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Rating Newest Oldest. Best Answer: Denaturation is a process in which proteins or nucleic acids lose their structure by application of some external stress or compound. If proteins in a living cell are denatured, this results in disruption of cell activity and possibly cell death. Source(s): http://en.wikipedia.org/wiki/Denaturatio...
denature deÂ·naÂ·ture (dÄ-nÄ'chÉr) v. deÂ·naÂ·tured, deÂ·naÂ·turÂ·ing, deÂ·naÂ·tures. To change the nature or natural qualities of. To render unfit to eat or drink without destroying usefulness in other applications, especially adding methyl alcohol to ethyl alcohol. To alter the chemical structure of a protein, as with heat, alkali, or acid, so that some of its original properties, especially its biological activity, are diminished or eliminated.