Malignancy is one of the most common causes and must be excluded. Hyperparathyroidism and other causes of hypercalcemia can coexist with malignancy. If calcium levels have been mildly elevated for months or years, malignancy is an unlikely cause. Hypercalcemia from malignancy usually is rapidly progressive; thus, rapidly rising calcium levels should increase suspicion of malignancy.
Kailua-Kona on Hawaiiâs Big Island is the site of Kona Brewing Companyâs brewery and first restaurant. The brewpub opened in November 1998. Prominently featured ohia wood found throughout the pub came from South Kona.
His new orchard in Kainaliu bore 9,000 pounds per acre in 1998-99, when the trees were 2 years and three months old. The same trees a year later will bear approximately 11,000 pounds per acre, he said. Yasuda estimates that healthy mature Kona Coffee trees should bear anywhere from 12,500 pounds per acre to 14,500 pounds per acre, depending on elevation and weather.