Features of thanatophoric dysplasia include macrocephaly, narrow bell-shaped thorax, normal trunk length, and severe shortening of the limbs. Other features of this condition include a narrow chest, short ribs, underdeveloped lungs, and an enlarged head with a large forehead and prominent, wide-spaced eyes. Most affected infants die of respiratory failure shortly after birth.
7.2 .2 Explain the process of DNA replication in prokaryotes, including the role of enzymes (helicase, DNA polymerase, RNA primase and DNA ligase), Okazaki fragments and deoxynucleoside triphosphates. The explanation of Okazaki fragments in relation to the direction of DNA polymerase III action is required.
DNA polymerase adds nucleotides onto the 3'OH end of the preceding nucleotide and carries out synthesis in the 5' to 3' direction down the length of the DNA. The result of DNA polymerase function is two copies of DNA that contain one original and one newly synthesized strand of DNA.To unlock this lesson you must be a Study.com Member.he result of DNA polymerase function is two copies of DNA that contain one original and one newly synthesized strand of DNA. To unlock this lesson you must be a Study.com Member.