The filament in a light bulb is housed in a sealed, oxygen-free chamber to prevent combustion. In the first light bulbs, all the air was sucked out of the bulb to create a near vacuum -- an area with no matter in it. Since there wasn't any gaseous matter present (or hardly any), the material could not combust.
Sertraline is used for a number of conditions including: major depression, obsessive-compulsive disorder (OCD), body dysmorphic disorder (BDD), posttraumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), panic disorder and social phobia (social anxiety disorder).
Plaquenil, the trade name for hydroxychloroquine, is a medication used for the treatment of malaria and also, in some cases, in the treatment of systemic lupus erythematosus and rheumatoid arthritis. It is not a narcotic.