The filament in a light bulb is housed in a sealed, oxygen-free chamber to prevent combustion. In the first light bulbs, all the air was sucked out of the bulb to create a near vacuum -- an area with no matter in it. Since there wasn't any gaseous matter present (or hardly any), the material could not combust.
Sertraline is used for a number of conditions including: major depression, obsessive-compulsive disorder (OCD), body dysmorphic disorder (BDD), posttraumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), panic disorder and social phobia (social anxiety disorder).
Hydroxychloroquine (HCQ), sold under the brand names Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine sensitive malaria. Other uses include rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Common side effects include vomiting, headache, changes in vision and muscle weakness.