From this knowledge management definition we can see that it depends upon the management of the organization's knowledge creation and conversion mechanisms; organizational memory and retrieval facilities; organizational learning; and organizational culture.
A leaky mitral valve, or mitral regurgitation, can develop when the valve flaps (called leaflets) do not close effectively. This can happen either because the valve flaps are scarred or defective, or because the heart has become enlarged, stretching the valve opening so much that the flaps no longer meet in the center.
Mitral valve prolapse (MVP) is a billowing of mitral valve leaflets into the left atrium during systole. The most common cause is idiopathic myxomatous degeneration. MVP is usually benign, but complications include mitral regurgitation, endocarditis, chordal rupture, and possibly thromboembolism.ey Points. MVP is most often caused by idiopathic myxomatous degeneration of the mitral valve and chordae tendineae. Mitral regurgitation (MR) is the most common complication. Heart sounds often include a sharp, mid-systolic click that occurs earlier with the Valsalva maneuver.