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Class Summary. All current antiepileptic drugs (AEDs), with the exception of ethosuximide, can be used in the treatment of complex partial seizures. The choice of an AED should be guided by certain general principles. The best-tolerated AED should be selected for the patient on the basis of side effects and drug interactions.
1 Medicine is the primary way in which seizures are controlled and is almost always the first therapy. 2  Different medicines help with different kinds of epilepsy and seizures. 3  Medicine controls seizures for about 7 out of 10 people living with epilepsy.