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Rating Newest Oldest. Best Answer: Denaturation is a process in which proteins or nucleic acids lose their structure by application of some external stress or compound. If proteins in a living cell are denatured, this results in disruption of cell activity and possibly cell death. Source(s): http://en.wikipedia.org/wiki/Denaturatio...
Trending Now. Answers. Best Answer: Denaturation of proteins involves the disruption and possible destruction of both the secondary and tertiary structures. Since denaturation reactions are not strong enough to break the peptide bonds, the primary structure (sequence of amino acids) remains the same after a denaturation process. Denaturation disrupts the normal alpha-helix and beta sheets in a protein and uncoils it into a random shape.